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steroid saponin

Any saponin derived from a hydroxysteroid.

ChEBI ID: 61655

Members (19)

MemberDefinitionRole
alpha-chaconinealpha-Chaconine
alpha-solanineA glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It is a trisccharide derivative of solanidine [(22beta)-solanid-5-en-3beta-ol].solanine
avenacoside bA steroid saponin obtained from grain and leaves of oats (Avena sativa) that is nuatigenin in which the hydroxy group at position 26 is converted to its beta-D-glucoside and in which the hydroxy group at position 3 is converted into its methyl alpha-L-rhamnopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)-beta-D-glucopyranosyl-(1->4)]-beta-D-glucopyranoside derivative.avenacoside B
beta-solamarineBeta-Solamarine
chinenoside iiChinenoside II
digoxigenin-mono(digitoxoside)A steroid saponin that consists of digoxigenin having a digitoxosyl residue attached at position 3.digoxigenin monodigitoxoside
digoxinA cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.digoxin
esculeoside aA steroid saponin that is spirosolane-3,23,27-triol in which the hydroxy group at position 23 is acetylated and the hydroxy groups at positions 3 and 27 are glycosylated by lycotetraosyl and a beta-D-glucopyranosyl moieties respectively. Isolated from the fruits of Lycopersicon esculentum, it exhibits cytotoxic activity.esculeoside A
estriol 17-glucuronide16alpha,17beta-Estriol 17-(beta-D-glucuronide)
estriol 3-sulfate 16-glucuronideEstriol 3-sulfate 16-glucuronide
furostanol iA spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of 26-(beta-D-glucopyranosyloxy)-3beta,22-dihydroxyfurost-5-ene via a glycosidic linkage. Found in several plant species including yams, asparagus and funugreek.protodioscin
lyonisideA steroid saponin that is sitosterol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has bee isolated from Panax japonicus var. major and Breynia fruticosa.daucosterol
oleandrinA steroid saponin that consists of oleandrigenin having a 2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl residue attached to the oxygen function at position 3.oleandrin
ophiopogonin bOphiopogonin B
ophiopogonin dOphiopogonin D
prosapogenin aProsapogenin A
stigmasterol 3-o-beta-d-glucopyranosideA steroid saponin that is (3beta,22E)-stigmasta-5,22-dien-3-ol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It is isolated from Symplocos lancifolia.stigmasterol 3-O-beta-D-glucoside
timosaponin b-iiMelongoside N
tuberosideTuberoside

Research

Studies (11,188)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19906,111 (54.62)18.7374
1990's1,826 (16.32)18.2507
2000's1,545 (13.81)29.6817
2010's1,331 (11.90)24.3611
2020's375 (3.35)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials966 (8.04%)5.53%
Reviews1,037 (8.63%)6.00%
Case Studies1,185 (9.86%)4.05%
Observational33 (0.27%)0.25%
Other8,799 (73.20%)84.16%