Page last updated: 2024-08-05 15:27:11

hyperglycemic agent

A drug which increases the blood glucose level.

ChEBI ID: 76916

Members (1)

MemberDefinitionClass
alloxanA member of the class of pyrimidones, the structure of which is that of perhydropyrimidine substituted at C-2, -4, -5 and -6 by oxo groups.alloxan

Research

Studies (2,982)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19901,648 (55.26)18.7374
1990's316 (10.60)18.2507
2000's407 (13.65)29.6817
2010's489 (16.40)24.3611
2020's122 (4.09)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials6 (0.18%)5.53%
Reviews52 (1.60%)6.00%
Case Studies2 (0.06%)4.05%
Observational0 (0.00%)0.25%
Other3,199 (98.16%)84.16%

Protein Targets (14)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Bloom syndrome protein isoform 1Homo sapiens (human)Potency39.810711
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency2.818411
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency39.810711
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency15.811411
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency10.000011
Microtubule-associated protein tauHomo sapiens (human)Potency2.665122
phosphopantetheinyl transferaseBacillus subtilisPotency14.125411
TDP1 proteinHomo sapiens (human)Potency1.636011
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency10.000011
USP1 protein, partialHomo sapiens (human)Potency89.125111
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency3.162311

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Chain A, XcogtXanthomonas campestrisKd1,000.000013