Diverticula

A pouch or sac developed from a tubular or saccular organ, such as the GASTROINTESTINAL TRACT.

Synonym
Diverticulosis
Diverticula
Diverticulum

Excerpt	Reference
"The diverticulum is lined on both sides with duodenal mucosa, and its eccentric opening is usually proximal in the sac."	( Carlson, HC; Fleming, CR; Newcomer, AD; Stephens, DH, 1975)
"Ureteral diverticulosis is a rare condition found mostly in men more than 50 years old and generally requires retrograde pyelography for diagnosis."	( Florence, TJ; Schoborg, TW, 1976)
"Congenital bladder diverticula are an uncommon cause of urinary retention in children."	( Fernbach, SK; Maizels, M; Valadez, R, 1987)
"Jugular bulb diverticulum is a rare condition that has never been reported in association with lower cranial nerve palsy."	( Atsuchi, M; Kobanawa, S; Shigeno, T; Tanaka, J, 2000)
"Diverticulosis is a common disease of not completely defined pathogenesis."	( Bianchetti, A; Croci, T; Di Marzo, V; Di Palo, S; Ferla, G; Guagnini, F; Matias, I; Mukenge, S; Valenti, M, 2006)
"Congenital cardiac diverticula are rare forms of cardiac malformations and their echo-Doppler features are herein discussed."	( Di Sessa, TG; Howard, SC; Salim, MA, 2006)
"Jejunal diverticula are rare lesions, and when complications arise, they pose diagnostic difficulties."	( Madankumar, MV; Maheshkumaar, GS; Palanivelu, C; Rajapandian, S; Rangarajan, M, 2008)
"Tracheal diverticulum is a rarely encountered entity characterized by single or multiple invaginations of the tracheal wall."	( Lee, KS; Son, JS, 2009)
"Jejunal diverticulosis is a rare malformation that is often asymptomatic."	( Baudoin, Y; Bourgouin, S; Butin, C; Hornez, E; Monchal, T; Salle, E; Sbardella, F; Thouard, H, 2010)
"Epiphrenic diverticula are outpouchings of the esophagus that retain some or all layers of the esophageal wall."	( Burgos, JD; Dias, A; Garcia, CJ; Hejazi, RA; Huerta, A; Zuckerman, MJ, 2011)
"Duodenal diverticula is a rare cause of upper GI bleeding and can be challenging to diagnose as they often require specialised endoscopy procedures such as endoscopy with a side-viewing scope."	( Andersen, JF; Lauritsen, ML; Wilhelmsen, M, 2014)
"Esophageal diverticulum is a rare condition that requires treatment only when symptoms are present."	( Fan, R; Guan, T; Li, Y; Xu, H; Yang, F; Zhou, J, 2023)

Excerpt	Reference
"Jejunal diverticula have characteristic findings on CT, appearing as discrete round or ovoid, contrast-, fluid-, or air-containing structures outside the expected lumen of the small bowel, with a smooth, barely discernible wall and no recognizable small-bowel folds."	( Fintelmann, F; Levine, MS; Rubesin, SE, 2008)

Excerpt	Reference
"All 10 patients with definite diverticular hemorrhage were treated endoscopically; none had recurrent bleeding or required surgery."	( Jensen, DM; Jutabha, R; Kovacs, TO; Machicado, GA, 2000)
"Cases of perforated large bowel diverticula living in the Norwich postal code region treated between 1995 and 1997 were identified."	( Day, NE; Hart, AR; Kennedy, HJ; Stebbings, WS, 2000)
"Adenocarcinoma of the female urethral diverticulum is rare and has been treated by surgery and/or radiation."	( Awakura, Y; Fukuyama, T; Itoh, N; Maeno, A; Nonomura, M, 2003)
"The treatment of Kommerell's diverticulum continues to evolve given advances in aortic surgery, cardiopulmonary bypass management, and endovascular techniques."	( Chen, EP; Keeling, WB; Kerendi, F, 2010)
"We present five cases of severe diverticular bleeding treated with injection of epinephrine and hemoclips."	( Alonso-Aguirre, P; Couto-Worner, I; Estévez-Prieto, E; González-Conde, B, 2013)
"To review the current treatment of diverticulosis and diverticular disease."	( Danese, S; Papa, A; Tursi, A, 2015)
"Esophageal diverticulum is a rare condition that requires treatment only when symptoms are present."	( Fan, R; Guan, T; Li, Y; Xu, H; Yang, F; Zhou, J, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	264 (56.77)	23.3326
1990's	50 (10.75)	12.5806
2000's	72 (15.48)	18.1394
2010's	63 (13.55)	28.8240
2020's	16 (3.44)	9.53

Drug	Relationship Strength	Studies	Trials
quinacrine	low	1	0
methane	low	3	0
citric acid, anhydrous	low	1	0
chlorine	low	3	0
hydrochloric acid	low	2	0
methylmalonic acid	low	1	0
formaldehyde	low	3	0
glycine	low	4	0
histamine	low	2	0
hydrogen	medium	1	1
phytic acid	low	1	0
niacinamide	low	1	0
nitrites	low	1	0
nitrous oxide	low	1	0
pyridoxal phosphate	low	1	0
pyridoxine	low	1	0
taurine	low	2	0
thiamine	low	1	0
uric acid	low	2	0
1-anilino-8-naphthalenesulfonate	low	1	0
3-methylcholanthrene	low	1	0
oxyquinoline	low	1	0
diatrizoic acid	low	3	0
amitriptyline	low	1	0
aspirin	low	7	0
atenolol	low	1	0
azathioprine	low	3	0
cefuroxime	low	1	0
chlorpheniramine	low	1	0
cimetidine	low	1	0
clioquinol	low	1	0
diazepam	low	1	0
diclofenac	low	2	0
pentetic acid	low	3	0
fentanyl	low	1	0
fluorouracil	low	3	0
furosemide	low	4	0
guaifenesin	low	2	0
lidocaine	low	2	0
imipramine	low	1	0
iodixanol	low	1	0
iohexol	low	2	0
iopromide	low	2	0
iothalamic acid	low	2	0
isoproterenol	low	1	0
mebendazole	low	1	0
meperidine	low	5	0
meprobamate	low	1	0
mesalamine	low	8	0
methantheline	low	3	0
methenamine	low	1	0
metoclopramide	low	1	0
metronidazole	low	2	0
midazolam	low	1	0
apnea	low	2	0
nalidixic acid	low	1	0
neostigmine	low	4	0
ofloxacin	low	1	0
omeprazole	low	2	0
pantoprazole	low	1	0
phenacetin	low	1	0
phenylbutazone	low	1	0
potassium chloride	low	1	0
procaine	low	1	0
propantheline	low	3	0
sulfamethoxazole	low	1	0
tranexamic acid	low	1	0
trimethoprim	low	3	0
zinc chloride	low	1	0
zolpidem	low	1	0
oxyphenonium	low	2	0
prednisolone	low	4	0
thyroxine	low	1	0
prednisone	low	2	0
sucrose	low	1	0
edetic acid	low	1	0
methylene blue	low	8	0
lactose	low	1	0
methionine	low	1	0
chloroform	low	1	0
ampicillin	low	3	0
isoprene	low	4	0
alpha-pinene	low	1	0
methylprednisolone	low	1	0
quinoline	low	1	0
2-methylquinoline	low	1	0
tolonium chloride	low	1	0
quinuclidines	low	1	0
framycetin	low	6	0
diatrizoate meglumine	low	1	0
iodohippuric acid	low	1	0
thiazoles	low	1	0
betamethasone	low	1	0
limestone	low	6	0
chenodeoxycholic acid	low	1	0
glycocholic acid	low	1	0
sulfur hexafluoride	low	2	0
enbucrilate	low	1	0
lanthanum	low	1	0
technetium	low	7	0
titanium	low	1	0
argon	low	1	0
gadolinium	low	3	0
holmium	low	1	0
barium sulfate	medium	76	1
calcium phosphate, dibasic, anhydrous	low	1	0
calcium phosphate, monobasic, anhydrous	low	1	0
tricalcium phosphate	low	3	0
trolamine salicylate	low	2	0
ammonium chloride	low	1	0
origen	low	1	0
cephalexin	low	2	0
cromolyn sodium	low	1	0
phenyl acetate	low	1	0
ursodeoxycholic acid	low	1	0
calcium oxalate	low	4	0
amoxicillin	low	2	0
ioxitalamic acid	low	1	0
paclitaxel	low	1	0
substance p	low	2	0
captopril	low	1	0
nicorandil	low	1	0
fomesafen	low	1	0
technetium tc 99m mertiatide	low	2	0
trazodone hydrochloride	low	5	0
iopamidol	low	2	0
tilbroquinol	low	1	0
delphinidin	low	2	0
fluorodeoxyglucose f18	low	11	0
picosulfate sodium	low	1	0
5-methyl-8-hydroxyquinoline	low	1	0
clarithromycin	low	2	0
fibrinogen	low	2	0
sr141716	low	1	0
entonox	low	1	0
sr 140333	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	1	0
methotrexate	low	1	0
xylose	low	2	0
calcium pyrophosphate	low	1	0
technetium tc 99m pentetate	low	5	0
lanthanum carbonate	low	1	0
intetrix	low	1	0
lignin	low	4	0
psyllium	low	1	0
dabigatran	low	1	0
cortisone	low	1	0
glycogen	low	1	0
fibrin	low	1	0
elastin	low	1	0
indican	low	1	0
metrizamide	low	2	0
tretinoin	low	1	0
retinol	low	2	0
pectins	low	2	0
clindamycin	low	1	0
diethylstilbestrol	low	1	0
melphalan	low	1	0
iothalamate meglumine	low	2	0
indigo carmine	low	1	0
digoxin	low	2	0
lincomycin	low	3	0
ranitidine	low	1	0
pica	low	1	0
nitinol	low	1	0
bilirubin	low	5	0
vitamin k semiquinone radical	low	1	0
clavulanic acid	low	1	0
anandamide	low	1	0
glyceryl 2-arachidonate	low	1	0
phenylephrine hydrochloride	low	2	0
morphine	low	8	0
nifuroxazide	low	1	0
lead	low	1	0
barium	low	8	0
bismuth	low	1	0
thallium	low	1	0
germacrene d	low	1	0
phosphorus	low	1	0
ici 118551	low	1	0
tetrodotoxin	low	1	0
nitrofurantoin	low	2	0
butylscopolammonium bromide	low	1	0
gadolinium dtpa	low	4	0
shu 508	low	1	0
amoxicillin-potassium clavulanate combination	low	1	0
sincalide	low	2	0
rivaroxaban	low	2	0
cgp 20712a	low	1	0
apixaban	low	1	0
struvite	low	2	0
edoxaban	low	1	0
lactulose	medium	1	1
technetium tc 99m disofenin	low	3	0
technetium tc 99m mebrofenin	low	1	0
indocyanine green	low	1	0
scopolamine hydrobromide	low	1	0
pituitrin	low	3	0
rifamycins	medium	7	1
clove	low	1	0
ants	low	1	0
nad	low	1	0
cholecystokinin	low	2	0
gastrins	low	1	0
glucagon	low	2	0
neuropeptide y	low	1	0
c-peptide	low	1	0
cellulose	low	18	0
sodium tetradecyl sulfate	low	1	0
sodium pertechnetate tc 99m	low	4	0
sodium ethylxanthate	low	1	0
chiniofon	low	1	0
ethyl cellulose	low	1	0
intrinsic factor	low	4	0
piperidines	low	1	0
methylcellulose	low	2	0
vasoactive intestinal peptide	low	1	0
ascorbic acid	low	1	0
tetracycline	low	17	0
chlortetracycline	low	1	0
salicylates	low	1	0
acenocoumarol	low	1	0
warfarin	low	3	0
phenprocoumon	low	1	0
kaolinite	low	1	0
technetium tc 99m lidofenin	low	1	0
vitamin b 12	low	26	0
ferric ammonium citrate	low	1	0
gallium ga 68 dotatate	low	1	0
technetium tc 99m medronate	low	5	0
exudates	low	5	0
technetium tc 99m dimercaptosuccinic acid	low	1	0
levoleucovorin	low	1	0
folic acid	low	5	0
cholestyramine resin	low	1	0
leptin	low	1	0

Protein Targets (1,395)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	6	0	0	6
thioredoxin reductase	26	0	0	26
USP1 protein, partial	26	0	0	26
TDP1 protein	54	0	0	54
vitamin D3 receptor isoform VDRA	20	0	0	20
importin subunit beta-1 isoform 1	8	0	0	8
flap endonuclease 1	14	0	0	14
serine/threonine-protein kinase PLK1	4	0	0	4
snurportin-1	8	0	0	8
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	9	0	0	9
GTP-binding nuclear protein Ran isoform 1	6	0	0	6
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	21	0	0	21
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
geminin	54	0	0	54
DNA polymerase kappa isoform 1	17	0	0	17
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	2	0	2
Transthyretin	0	1	2	6
Fatty acid-binding protein, intestinal	0	2	1	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	4	4	8
Cyclin-dependent kinase 2	0	1	2	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	6	0	0	6
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
glucocorticoid receptor [Homo sapiens]	47	0	0	47
peroxisome proliferator-activated receptor delta	31	0	0	31
peroxisome proliferator activated receptor gamma	37	0	0	37
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	14	0	0	14
Cytochrome P450 1A2	0	3	1	6
Cytochrome P450 2A6	0	1	0	1
Neutrophil cytosol factor 1	0	2	0	2
Cytochrome P450 2A5	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Luciferase	26	0	0	26
pregnane X receptor	10	0	0	10
phosphopantetheinyl transferase	22	0	0	22
RAR-related orphan receptor gamma	48	0	0	48
SMAD family member 2	14	0	0	14
SMAD family member 3	14	0	0	14
Microtubule-associated protein tau	23	0	0	23
AR protein	62	0	0	62
caspase 7, apoptosis-related cysteine protease	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	42	0	0	42
nuclear receptor subfamily 1, group I, member 3	43	0	0	43
retinoic acid nuclear receptor alpha variant 1	46	0	0	46
estrogen-related nuclear receptor alpha	57	0	0	57
farnesoid X nuclear receptor	32	0	0	32
pregnane X nuclear receptor	47	0	0	47
estrogen nuclear receptor alpha	71	0	0	71
caspase-3	7	0	0	7
euchromatic histone-lysine N-methyltransferase 2	53	0	0	53
aryl hydrocarbon receptor	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	31	0	0	31
activating transcription factor 6	20	0	0	20
thyroid hormone receptor beta isoform a	14	0	0	14
heat shock protein beta-1	19	0	0	19
nuclear factor erythroid 2-related factor 2 isoform 1	48	0	0	48
Voltage-dependent calcium channel gamma-2 subunit	23	0	0	23
Cellular tumor antigen p53	44	0	0	44
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	4	0	4
Aldo-keto reductase family 1 member B1	0	10	0	10
Adenosine receptor A3	0	8	0	8
Alpha-1B adrenergic receptor	0	16	1	17
Glutamate receptor 2	23	0	1	24
Acetylcholinesterase	0	7	0	7
Sodium-dependent noradrenaline transporter	0	12	1	13
Aryl hydrocarbon receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	18	1	19
hypoxia-inducible factor 1 alpha subunit	19	0	0	19
GLI family zinc finger 3	48	0	0	48
estrogen receptor 2 (ER beta)	28	0	0	28
progesterone receptor	31	0	0	31
retinoid X nuclear receptor alpha	35	0	0	35
vitamin D (1,25- dihydroxyvitamin D3) receptor	35	0	0	35
thyrotropin-releasing hormone receptor	4	0	0	4
Histone H2A.x	26	0	0	26
thyroid hormone receptor beta isoform 2	39	0	0	39
huntingtin isoform 2	8	0	0	8
nuclear receptor ROR-gamma isoform 1	13	0	0	13
Catechol O-methyltransferase	0	3	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	23	0	0	23
G	22	0	0	22
thyroid stimulating hormone receptor	19	0	0	19
chromobox protein homolog 1	29	0	0	29
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	10	0	0	10
muscleblind-like protein 1 isoform 1	11	0	0	11
Interferon beta	27	0	0	27
HLA class I histocompatibility antigen, B alpha chain	22	0	0	22
Inositol hexakisphosphate kinase 1	22	0	0	22
cytochrome P450 2C9, partial	22	0	0	22
thyroid stimulating hormone receptor	20	0	0	20
mitogen-activated protein kinase 1	11	0	0	11
Nuclear receptor ROR-gamma	13	2	2	17
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	18	0	0	18
acetylcholinesterase	18	0	0	18
ATAD5 protein, partial	17	0	0	17
Fumarate hydratase	11	0	0	11
NFKB1 protein, partial	6	0	0	6
PPM1D protein	8	0	0	8
Thrombopoietin	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
EWS/FLI fusion protein	27	0	0	27
cytochrome P450 2D6	22	0	0	22
polyprotein	11	0	0	11
v-jun sarcoma virus 17 oncogene homolog (avian)	26	0	0	26
cytochrome P450 2D6 isoform 1	9	0	0	9
cellular tumor antigen p53 isoform a	8	0	0	8
cytochrome P450 2C9 precursor	5	0	0	5
D(1A) dopamine receptor	8	0	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
peripheral myelin protein 22	28	0	0	28
survival motor neuron protein isoform d	15	0	0	15
cytochrome P450 3A4 isoform 1	20	0	0	20
muscarinic acetylcholine receptor M1	14	0	0	14
lethal factor (plasmid)	13	0	0	13
lamin isoform A-delta10	43	0	0	43
Gamma-aminobutyric acid receptor subunit pi	20	7	2	29
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	0	0	9
ATP-binding cassette sub-family C member 3	0	45	0	45
Multidrug resistance-associated protein 4	0	47	0	49
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Solute carrier organic anion transporter family member 1A4	0	2	0	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
5-hydroxytryptamine receptor 4	0	8	0	8
Lysine-specific demethylase PHF2	0	1	0	1
Bile salt export pump	0	71	0	72
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Integrin beta-3	6	2	0	8
ATP-dependent translocase ABCB1	0	5	0	5
Muscarinic acetylcholine receptor M2	0	8	0	8
Muscarinic acetylcholine receptor M4	0	8	0	8
ATP-dependent translocase ABCB1	0	12	2	19
Integrin alpha-IIb	6	1	0	7
Beta-1 adrenergic receptor	0	8	3	11
Muscarinic acetylcholine receptor M5	0	7	0	7
Alpha-2A adrenergic receptor	0	15	2	17
Cytochrome P450 2C8	0	3	0	3
Thyroid hormone receptor alpha	0	1	1	2
Thyroid hormone receptor beta	0	1	1	2
Muscarinic acetylcholine receptor M1	0	10	0	10
Beta-3 adrenergic receptor	0	3	2	5
D(2) dopamine receptor	0	12	0	12
Androgen receptor	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	20	7	2	29
Lethal factor	0	2	0	2
Alpha-2B adrenergic receptor	0	10	2	12
Thyroid hormone receptor beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	20	7	2	29
Gamma-aminobutyric acid receptor subunit gamma-2	20	7	2	29
Gamma-aminobutyric acid receptor subunit alpha-5	20	7	2	29
Gamma-aminobutyric acid receptor subunit alpha-3	20	7	2	29
Muscarinic acetylcholine receptor M3	0	9	0	9
ATP-dependent translocase ABCB1	0	6	0	6
Substance-K receptor	0	8	0	8
D(1A) dopamine receptor	0	7	0	7
D(4) dopamine receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	20	7	2	29
Gamma-aminobutyric acid receptor subunit alpha-2	20	7	2	29
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Histamine H2 receptor	0	9	2	11
Endothelin-1 receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	12	0	12
5-hydroxytryptamine receptor 2C	0	9	0	9
Gamma-aminobutyric acid receptor subunit alpha-4	20	7	2	29
Gamma-aminobutyric acid receptor subunit gamma-3	20	7	2	29
Lysine-specific demethylase 5A	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	20	7	2	29
B2 bradykinin receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	10	0	10
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	4	0	4
Mu-type opioid receptor	0	9	3	13
D(3) dopamine receptor	0	12	0	12
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	4	0	4
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	11	2	14
Kappa-type opioid receptor	0	9	1	11
5-hydroxytryptamine receptor 2B	0	10	0	10
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Histamine H2 receptor	13	4	3	21
D(1A) dopamine receptor	5	0	0	5
5-hydroxytryptamine receptor 6	0	7	0	7
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	24	0	1	25
Gamma-aminobutyric acid receptor subunit alpha-1	20	8	2	30
Gamma-aminobutyric acid receptor subunit beta-3	20	7	2	29
Gamma-aminobutyric acid receptor subunit beta-2	20	7	2	29
Sodium channel protein type 7 subunit alpha	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Sodium-dependent dopamine transporter	0	7	0	7
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
Sodium channel protein type 5 subunit alpha	0	4	0	4
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	5	0	5
Lysine-specific demethylase 7A	0	1	0	1
GABA theta subunit	20	7	2	29
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	42	0	42
Sodium channel protein type 2 subunit alpha	0	3	0	3
Ataxin-2	26	0	0	26
Sigma non-opioid intracellular receptor 1	0	9	1	10
Gamma-aminobutyric acid receptor subunit epsilon	20	7	2	29
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	1	2
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	3	0	3
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	3	0	3
Sodium channel protein type 10 subunit alpha	0	3	0	3
ATP-dependent phosphofructokinase	16	0	0	16
Chain A, HADH2 protein	22	0	0	22
Chain B, HADH2 protein	22	0	0	22
GLS protein	15	0	0	15
cytochrome P450 family 3 subfamily A polypeptide 4	39	0	0	39
arylsulfatase A	11	0	0	11
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
Solute carrier family 22 member 1	0	12	0	14
Albumin	0	0	4	4
High affinity nerve growth factor receptor	0	1	2	3
Muscarinic acetylcholine receptor M1	0	6	0	6
Muscarinic acetylcholine receptor M3	0	4	0	4
Muscarinic acetylcholine receptor M4	0	4	0	4
5-hydroxytryptamine receptor 2C	0	5	0	6
Muscarinic acetylcholine receptor M5	0	5	0	5
Muscarinic acetylcholine receptor M2	0	5	1	6
Angiotensin-converting enzyme	0	4	0	5
5-hydroxytryptamine receptor 2A	0	7	1	8
Alpha-2C adrenergic receptor	0	10	1	11
5-hydroxytryptamine receptor 1A	0	8	2	10
D(1B) dopamine receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	5	0	7
Alpha-1D adrenergic receptor	0	7	1	8
5-hydroxytryptamine receptor 1B	0	4	0	4
5-hydroxytryptamine receptor 1D	0	3	0	3
5-hydroxytryptamine receptor 1F	0	3	0	3
5-hydroxytryptamine receptor 2B	0	5	0	5
5-hydroxytryptamine receptor 6	0	2	0	2
Histamine H1 receptor	0	4	1	5
5-hydroxytryptamine receptor 7	0	2	0	2
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 5B	0	2	0	2
Histamine H1 receptor	0	9	2	11
UDP-glucuronosyltransferase 1A3	0	0	0	4
5-hydroxytryptamine receptor 3A	0	4	0	4
5-hydroxytryptamine receptor 7	0	5	0	5
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	1	3
5-hydroxytryptamine receptor 4	0	3	0	4
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
5-hydroxytryptamine receptor 3B	0	4	0	4
Histamine H3 receptor	0	2	2	4
Chain A, Beta-lactamase	15	0	0	15
Chain A, 2-oxoglutarate Oxygenase	25	0	0	25
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	2
Bile salt export pump	0	9	0	9
Beta-lactamase SHV-1	0	1	0	3
Beta-lactamase SHV-1	0	2	0	5
Cytochrome P450 2C9	0	14	1	16
Beta-lactamase	0	1	0	4
Kappa-type opioid receptor	0	4	0	7
Solute carrier family 15 member 1	0	6	0	6
Solute carrier family 15 member 1	0	4	0	4
Cytochrome P450 2J2	0	11	0	11
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Solute carrier family 15 member 2	0	3	0	4
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	2
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
Chain A, Cruzipain	9	0	0	9
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	1	2	6
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	17	0	0	17
DNA polymerase beta	5	0	0	5
Carbonic anhydrase 1	0	12	0	15
Carbonic anhydrase 2	0	13	2	19
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-lactamase OXA-7	0	0	0	2
10 kDa heat shock protein, mitochondrial	0	5	0	5
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Thiosulfate sulfurtransferase	0	5	0	5
Metallo-beta-lactamase VIM-13	0	1	0	4
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	3
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	1	0	3
60 kDa chaperonin	0	7	0	7
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	1	3
10 kDa chaperonin	0	7	0	7
Metallo-b-lactamase	0	0	0	4
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	5
Histamine H3 receptor	0	1	0	4
Beta-lactamase class B VIM-2	0	1	2	7
Beta-lactamase VIM-1	0	1	0	4
Chain A, Ferritin light chain	13	0	0	13
Bloom syndrome protein isoform 1	12	0	0	12
Fatty-acid amide hydrolase 1	0	3	0	3
Fatty-acid amide hydrolase 1	0	1	0	2
Potassium channel subfamily K member 3	0	2	0	2
Fatty acid-binding protein, liver	0	3	0	3
Glutamate receptor 1	0	0	1	1
Glutamate receptor 3	0	0	1	1
Glutamate receptor 4	0	0	1	1
Cannabinoid receptor 1	0	4	3	12
Cannabinoid receptor 2	0	4	2	10
Cannabinoid receptor 1	0	4	1	5
Cannabinoid receptor 2	0	1	1	2
Fatty-acid amide hydrolase 1	0	4	0	5
Corticotropin-releasing factor receptor 2	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Potassium channel subfamily K member 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	0	1	2
Cannabinoid receptor 2	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)	0	1	0	1
Coagulation factor X	0	1	0	1
Prothrombin	0	5	0	5
Coagulation factor X	0	7	0	7
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Trypsin-3	0	2	0	2
neuropeptide S receptor isoform A	6	0	0	6
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	11	0	0	11
IDH1	20	0	0	20
nuclear factor erythroid 2-related factor 2 isoform 2	14	0	0	14
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Polyphenol oxidase 2	0	1	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	2	0	2
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
interleukin 8	14	0	0	14
hypothetical protein, conserved	2	0	0	2
glucocerebrosidase	6	0	0	6
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	7	0	7
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	4	0	4
Fatty acid-binding protein, liver	0	5	0	5
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	5	0	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	5	0	5
Adenosine receptor A1	0	1	0	2
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	3	0	3
Prostaglandin G/H synthase 2	0	7	0	7
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	1	3
regulator of G-protein signaling 4	14	0	0	14
Beta-1 adrenergic receptor	0	0	2	3
Beta-2 adrenergic receptor	0	6	4	11
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
TAR DNA-binding protein 43	12	0	0	12
Beta-2 adrenergic receptor	0	1	3	4
P53	1	0	0	1
peripheral myelin protein 22 isoform 1	6	0	0	6
hemoglobin subunit beta	2	0	0	2
M-phase phosphoprotein 8	10	0	0	10
ATPase family AAA domain-containing protein 5	21	0	0	21
Protein-arginine deiminase type-4	0	9	0	9
nuclear receptor subfamily 1, group I, member 2	7	0	0	7
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	12	3	20
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	4	0	0	4
Inositol monophosphatase 1	4	0	0	4
Solute carrier organic anion transporter family member 1B3	0	6	0	10
Solute carrier organic anion transporter family member 1B1	0	6	0	9
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
15-lipoxygenase, partial	10	0	0	10
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	3	1	4
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Beta-lactamase TEM	0	3	0	5
Mu-type opioid receptor	0	7	1	8
Beta-lactamase	0	3	0	4
Beta-lactamase	0	3	0	3
Angiotensin-converting enzyme 2	0	1	1	2
bromodomain adjacent to zinc finger domain 2B	10	0	0	10
Solute carrier family 22 member 8	0	3	0	3
Smad3	9	0	0	9
mu-type opioid receptor isoform MOR-1	0	0	2	2
D(3) dopamine receptor isoform e	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	2	2
Caspase-7	7	0	0	7
caspase-3	7	0	0	7
Vitamin D3 receptor	0	2	2	4
Retinoic acid receptor RXR-alpha	0	1	3	4
Ileal sodium/bile acid cotransporter	0	2	0	2
Bile acid receptor	0	0	1	1
G-protein coupled bile acid receptor 1	0	1	3	4
Bile acid receptor	0	1	2	3
streptokinase A precursor	0	0	5	5
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	3	0	3
30S ribosomal protein S7	0	3	0	3
50S ribosomal protein L15	0	3	0	3
Cytochrome P450 3A4	0	10	2	13
50S ribosomal protein L10	0	3	0	3
50S ribosomal protein L11	0	3	0	3
50S ribosomal protein L7/L12	0	3	0	3
50S ribosomal protein L19	0	3	0	3
50S ribosomal protein L1	0	3	0	3
50S ribosomal protein L20	0	3	0	3
50S ribosomal protein L27	0	3	0	3
50S ribosomal protein L28	0	3	0	3
50S ribosomal protein L29	0	3	0	3
50S ribosomal protein L31	0	3	0	3
50S ribosomal protein L31 type B	0	3	0	3
50S ribosomal protein L32	0	3	0	3
50S ribosomal protein L33	0	3	0	3
50S ribosomal protein L34	0	3	0	3
50S ribosomal protein L35	0	3	0	3
50S ribosomal protein L36	0	3	0	3
30S ribosomal protein S10	0	3	0	3
30S ribosomal protein S11	0	3	0	3
30S ribosomal protein S12	0	3	0	3
30S ribosomal protein S13	0	3	0	3
30S ribosomal protein S16	0	3	0	3
30S ribosomal protein S18	0	3	0	3
30S ribosomal protein S19	0	3	0	3
30S ribosomal protein S20	0	3	0	3
30S ribosomal protein S2	0	3	0	3
30S ribosomal protein S3	0	3	0	3
30S ribosomal protein S4	0	3	0	3
30S ribosomal protein S5	0	3	0	3
30S ribosomal protein S8	0	3	0	3
30S ribosomal protein S9	0	3	0	3
50S ribosomal protein L13	0	3	0	3
50S ribosomal protein L14	0	3	0	3
50S ribosomal protein L16	0	3	0	3
50S ribosomal protein L23	0	3	0	3
30S ribosomal protein S15	0	3	0	3
50S ribosomal protein L17	0	3	0	3
50S ribosomal protein L21	0	3	0	3
50S ribosomal protein L30	0	3	0	3
50S ribosomal protein L6	0	3	0	3
30S ribosomal protein S14	0	3	0	3
30S ribosomal protein S17	0	3	0	3
30S ribosomal protein S1	0	3	0	3
50S ribosomal protein L18	0	3	0	3
50S ribosomal protein L2	0	3	0	3
50S ribosomal protein L3	0	3	0	3
50S ribosomal protein L24	0	3	0	3
50S ribosomal protein L4	0	3	0	3
50S ribosomal protein L22	0	3	0	3
50S ribosomal protein L5	0	3	0	3
30S ribosomal protein S21	0	3	0	3
50S ribosomal protein L25	0	3	0	3
50S ribosomal protein L36 2	0	3	0	3
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Carbonic anhydrase 4	0	5	0	8
Carbonic anhydrase	0	3	0	4
Carbonic anhydrase 15	0	3	0	4
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
MBT domain-containing protein 1	0	1	0	1
Solute carrier family 22 member 1	0	6	0	7
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Solute carrier family 22 member 2	0	6	0	7
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	3	0	3
alpha-galactosidase	5	0	0	5
cytochrome P450 2C19 precursor	9	0	0	9
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	5	0	7
Solute carrier family 22 member 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Cytochrome P450 2D6	0	6	2	8
Potassium-transporting ATPase alpha chain 1	0	2	0	2
Histamine H1 receptor	0	1	4	5
Potassium-transporting ATPase subunit beta	0	2	0	2
Aldehyde oxidase	0	3	0	3
Solute carrier family 22 member 6	0	3	0	5
Multidrug and toxin extrusion protein 2	0	4	0	4
Solute carrier family 22 member 8	0	4	0	7
Multidrug and toxin extrusion protein 1	0	9	0	9
Histamine H4 receptor	0	3	2	5
Solute carrier family 22 member 11	0	1	0	3
Solute carrier family 22 member 4	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	4	0	4
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Neutrophil elastase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Cytochrome P450 2B6	0	4	0	4
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
glp-1 receptor, partial	11	0	0	11
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	3	0	3
nonstructural protein 1	9	0	0	9
LAP4	0	0	1	1
MEP2	0	0	1	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	7	0	0	7
heat shock protein HSP 90-alpha isoform 2	0	3	0	4
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Histone deacetylase 3	0	1	0	1
Carbonic anhydrase 12	0	1	0	4
Amyloid-beta precursor protein	1	5	0	6
Carbonic anhydrase 3	0	1	0	3
Botulinum neurotoxin type A	0	3	0	3
Spike glycoprotein	0	1	0	1
Carbonic anhydrase 6	0	3	0	6
Alpha-1D adrenergic receptor	0	9	1	10
Carbonic anhydrase 5A, mitochondrial	0	3	0	6
Alpha-synuclein	7	4	0	11
Carbonic anhydrase 7	0	2	0	5
Histone deacetylase 4	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Histone deacetylase 1	0	1	0	1
Carbonic anhydrase 9	0	5	1	9
Beta-galactosidase	0	0	1	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	1	2
Carbonic anhydrase 13	0	2	0	5
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Carbonic anhydrase 14	0	1	0	4
Histone deacetylase 5	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	1
Liver carboxylesterase 1	0	0	0	2
Cytochrome P450 2C19	0	5	1	8
Rap guanine nucleotide exchange factor 4	1	0	0	1
endonuclease IV	4	0	0	4
dopamine D1 receptor	4	0	0	4
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	1	2	3
Plasminogen	0	3	1	4
Coagulation factor XII	0	2	0	2
Tissue-type plasminogen activator	0	1	0	1
Vitamin K-dependent protein C	0	1	0	1
Serine protease hepsin	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	0	2
Vascular endothelial growth factor receptor 2	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Hsf1 protein	0	0	2	2
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	2	7	10
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	2	1	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	3	6
Translocator protein	0	3	2	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	3	1	4
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	3	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-2	0	3	2	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Aldo-keto reductase family 1 member B10	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Dihydrofolate reductase	0	5	0	6
Cytochrome c oxidase subunit 2	0	1	0	1
Interleukin-8	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	3
UDP-glucuronosyltransferase 2B7	0	5	0	6
UDP-glucuronosyltransferase 1-6	0	6	0	6
UDP-glucuronosyltransferase 1A1	0	7	0	7
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	5	0	5
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase 4	0	1	0	2
P2Y purinoceptor 12	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
67.9K protein	9	0	0	9
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	1	3	4
Estrogen receptor	0	4	1	5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Vasopressin V1a receptor	0	2	0	2
Estrogen-related receptor gamma	0	0	1	1
UDP-glucose 4-epimerase	0	1	0	1
Estrogen receptor beta	0	4	1	5
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	0	5
Cysteinyl leukotriene receptor 1	0	2	0	2
PAX8	0	0	0	1
STAT3, partial	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
tumor necrosis factor	1	0	0	1
ras-related protein Rab-9A	4	0	0	4
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	4	0	4
Sodium/potassium-transporting ATPase subunit beta-1	0	4	0	4
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Replicase polyprotein 1ab	0	2	1	3
Sodium/potassium-transporting ATPase subunit alpha-3	0	3	0	3
Sodium/potassium-transporting ATPase subunit beta-2	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	4	0	4
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	3	0	3
Sodium/potassium-transporting ATPase subunit gamma	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-4	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
Eyes absent homolog 2	0	1	0	1
NS5	0	0	1	1
Parkin	4	0	0	4
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Glucose transporter	0	1	0	1
Serine hydrolase RBBP9	0	1	0	1
Hexose transporter 1	0	1	0	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	2
Dihydroorotate dehydrogenase	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Delta-type opioid receptor	0	4	0	5
Delta-type opioid receptor	0	5	1	7
Mu-type opioid receptor	0	5	3	11
Kappa-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	4	1	7
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Vpr	3	0	0	3
Solute carrier family 22 member 8	0	0	0	1
Thymidylate synthase	0	4	0	4
Aromatase	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Thymidylate synthase	0	5	0	5
Dihydrofolate reductase	0	4	3	7
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	4
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Serum paraoxonase/arylesterase 1	0	3	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	3	0	3
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
CDGSH iron-sulfur domain-containing protein 1	0	6	0	6
Carbonic anhydrase 5B, mitochondrial	0	2	0	4
histone acetyltransferase KAT2A isoform 1	16	0	0	16
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	4	2	7
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	2	7
Glutamate receptor ionotropic, NMDA 2B	0	4	2	7
Glutamate receptor ionotropic, NMDA 2C	0	4	2	7
Large neutral amino acids transporter small subunit 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	4	2	7
Proton-coupled amino acid transporter 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	4	2	7
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Glutamate receptor ionotropic, NMDA 3A	0	4	2	7
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Sodium/bile acid cotransporter	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Bile salt export pump	0	0	0	1
Rap guanine nucleotide exchange factor 3	3	0	0	3
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	7	0	0	7
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Solute carrier family 22 member 3	0	3	0	4
Plasma kallikrein	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
5-hydroxytryptamine receptor 1D	0	0	0	1
Metabotropic glutamate receptor 5	0	2	1	3
Carbonic anhydrase	0	0	0	2
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Snq2p	0	0	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
Major prion protein	0	0	2	2
5-hydroxytryptamine receptor 1A	0	1	0	1
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	6	0	6
Alpha-2A adrenergic receptor	0	6	0	6
Sodium-dependent dopamine transporter	0	2	1	3
D(1B) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	5	0	5
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(2) dopamine receptor	0	3	1	4
Envelope glycoprotein	0	0	1	1
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	3	0	3
histone deacetylase 9 isoform 3	4	0	0	4
Peptidylglycine alpha-amidating monooxygenase	0	0	0	1
NPYLR7B	0	0	2	2
beta-2 adrenergic receptor	3	0	0	3
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	4
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	1	1	2
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	2	2
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	2	2
Oxytocin receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	2	2
Taste receptor type 2 member 13	0	0	2	2
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	2	2
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	2	2
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Tyrosine-protein kinase ABL1	0	3	1	4
Methionine aminopeptidase	0	1	0	1
Calmodulin-domain protein kinase 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Kappa-type opioid receptor	0	3	1	5
Metallo-beta-lactamase VIM-19	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	0	0	1
Tumor necrosis factor	0	1	0	1
Neuraminidase	0	1	0	1
60 kDa chaperonin	0	3	0	3
Platelet-activating factor receptor	1	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Cystine/glutamate transporter	0	1	0	1
Hydroxyacid oxidase 1	0	1	0	1
large T antigen	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	5	0	5
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	5	0	6
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Reduced folate transporter	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	2	0	3
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	2	0	0	2
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	3
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	3	1	4
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	1	0	0	1
tumor susceptibility gene 101 protein	2	0	0	2
Serine racemase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
5-hydroxytryptamine receptor 3E	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
D(2) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Lactoperoxidase	0	1	0	1
5-hydroxytryptamine receptor 3D	0	0	1	1
5-hydroxytryptamine receptor 3C	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	2	0	2
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	2	2
Mu-type opioid receptor	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit A	0	3	0	4
DNA gyrase subunit B	0	3	0	4
Pyruvate kinase PKM	0	1	0	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	2	0	3
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Cholinesterase	0	3	0	3
Cholinesterase	0	2	0	2
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Microphthalmia-associated transcription factor	0	0	0	1
PINK1	1	0	0	1
Signal transducer and activator of transcription 3	0	0	1	1
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
DNA topoisomerase 4 subunit A	0	1	0	1
Multidrug resistance protein MdtK	0	0	1	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
Mcl-1	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	2	0	2
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Chain A, Bacterial leucyl aminopeptidase	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Thermolysin	0	2	0	3
72 kDa type IV collagenase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	0	1
Genome polyprotein	0	1	0	1
Tubulin alpha-1A chain	0	0	1	2
Tubulin beta chain	0	0	1	1
Tubulin beta-4A chain	0	1	1	3
Integrin alpha-V	0	1	0	1
Tubulin beta chain	0	1	1	3
Tubulin alpha-3C chain	0	1	1	3
Apoptosis regulator Bcl-2	0	1	0	1
Fibroblast growth factor receptor 1	0	1	0	1
Cholecystokinin receptor type A	0	4	2	6
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	0	1
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	1	1	3
Beta-tubulin	0	1	0	1
Tubulin beta-8 chain	0	1	1	3
Tubulin beta-2B chain	0	0	1	3
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
Similar to alpha-tubulin isoform 1	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	0	2
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Cytochrome P450 1A2	0	0	0	2
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Protease	0	4	1	5
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)	0	1	0	1
Chain A, Beta-arrestin 1	0	0	1	1
Beta-lactamase	0	0	0	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	1	0	1
P2X purinoceptor 4	0	0	1	1
Trans-sialidase	0	1	0	1
Trans-sialidase	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Pyridoxal kinase	0	0	0	1
N	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
Riboflavin-binding protein	0	1	1	2
Major prion protein	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
DNA-directed RNA polymerase subunit alpha	0	1	0	1
DNA-directed RNA polymerase subunit omega	0	1	0	1
DNA-directed RNA polymerase subunit beta'	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Phospholipase A2, membrane associated	0	1	0	1
Acidic phospholipase A2 2	0	1	0	1
Trypanothione reductase	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Nicotinamide N-methyltransferase	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, Activated Factor Xa Heavy Chain	0	1	0	1
Suppressor of tumorigenicity 14 protein	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	2	2	4
Gastrin/cholecystokinin type B receptor	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Orexin receptor type 1	0	0	0	1
Cathepsin B	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
N-arachidonyl glycine receptor	0	1	0	1
G-protein coupled receptor 55	0	0	1	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Stromelysin-1	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Integrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	2	4	6
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Urokinase-type plasminogen activator	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase 2	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Context

Treatment

Research

Studies (465)

Protein Targets (1,395)

Diverticula

Synonyms(3)

Research Excerpts

Overview

Context

Treatment

Research

Studies (465)

Drugs Studied (266)

Protein Targets (1,395)