Periodontitis, Acute Nonsuppurative

Synonym
Periodontitis, Apical
Periodontitis, Acute Nonsuppurative

Excerpt	Reference
"Apical periodontitis is a chronic inflammatory disorder of periradicular tissues caused by aetiological agents of endodontic origin."	( Nair, PN, 2006)
"Apical periodontitis is caused by a polymicrobial infection, and a calcium hydroxide/chlorhexidine paste is effective in reducing the number of bacteria inside root canals when applied as a root canal dressing."	( Da Silva, LA; Ito, IY; Junior, FM; Leonardo, MR; Nelson-Filho, P; Paula-Silva, FW, 2011)
"Apical periodontitis is an inflammatory disease of the periradicular tissues caused by the host's immune response to infection of the root canal system."	( Bair, E; Chan, LT; Khan, AA; Naqvi, AR; Nares, S; Self-Fordham, J; Zhong, S, 2013)
"Apical periodontitis is an inflammation and destruction of periapical tissues."	( Chen, Z; Sun, Q; Wan, C; Yang, J; Yuan, G; Zhang, J; Zhang, L, 2014)
"Apical periodontitis is an inflammatory response around the root tip of a tooth to microbial infection of the root canal system."	( de Soet, JJ; van der Waal, SV, 2015)
"Periapical periodontitis is a common oral disease caused by bacterial invasion of the tooth pulp, which usually leads to local release of pro-inflammatory cytokines and osteolytic lesion."	( Huang, X; Jiang, Y; Lin, J; Liu, Q; Luo, W; Wang, F; Zhang, F; Zhang, H; Zhang, Y; Zhou, P, 2017)
"Apical periodontitis is an inflammatory disease in the periradicular region of teeth that results from infection by multispecies bacterial biofilm residing in the root canal system."	( Ahn, KB; Han, SH; Kim, AR; Kum, KY; Park, OJ; Perinpanayagam, H; Yoo, YJ; Yun, CH, 2019)
"Apical periodontitis is caused by biofilm-mediated root canal infection."	( Han, SH; Kang, M; Kim, AR; Kum, KY; Perinpanayagam, H; Yoo, YJ; Yun, CH, 2020)
"Persistent apical periodontitis is a critical challenge for endodontists."	( Cheng, L; Guo, X; Lan, F; Li, M; Peng, X; Ren, B; Sun, Y; Wang, H; Wang, S; Wang, Z; Weir, MD; Wu, Y; Xu, HHK; Zhou, X, 2022)
"Chronic apical periodontitis is a prevalent oral disease characterized by bone loss, and its underlying mechanisms remain unclear."	( Jia, T; Li, H; Tao, J; Wang, G; Yuan, F; Zhang, B; Zhang, X, 2023)

Excerpt	Reference
"Human apical periodontitis has yet to be studied for the presence of cGAS."	( Du, J; Huang, D; Ji, X; Liu, L; Wang, L; Yang, F; Zeng, Y; Zhang, L, 2023)

Excerpt	Reference
"The microbiology and treatment of apical periodontitis was studied in 62 patients, followed-up for 1 year."	( Haapasalo, M; Hovi, T; Kerosuo, E; Kontiainen, S; Ranta, H; Ranta, K; Suuronen, R; Valtonen, V, 1988)
"The microbial flora in treatment-resistant apical periodontitis is dominated by E."	( Ellington, MJ; Haapasalo, M; Reynaud Af Geijersstam, AH; Warner, M; Woodford, N, 2006)
"Fifteen teeth with post-treatment apical periodontitis were sampled before (s1) and after (s2) CMP."	( Almeida, JF; Endo, MS; Ferraz, CC; Gomes, BP; Martinho, FC; Zaia, AA, 2012)
"A total of 126 patients requiring treatment of apical periodontitis and pulp necrosis were randomly assigned to 2 groups according to the solution used for irrigation: 5."	( Almeida, G; Cunha, RS; da Silveira Bueno, CE; De Martin, AS; Marques, E; Nowakowski, A, 2012)
"Root canal-treated teeth with apical periodontitis were randomly distributed into 2 groups."	( Enersen, M; Kristoffersen, AK; Mdala, I; Rôças, IN; Rodrigues, RC; Siqueira, JF; Zandi, H; Ørstavik, D, 2016)
"Forty-three teeth with posttreatment apical periodontitis were selected for retreatment."	( Enersen, M; Kristoffersen, AK; Mdala, I; Rôças, IN; Rodrigues, RCV; Siqueira, JF; Zandi, H; Ørstavik, D, 2017)
"Prevention or treatment of apical periodontitis is aimed at disinfecting the root canal system so that the periradicular tissues are not vulnerable to attack from microbiota within the tooth."	( Simon, SR; Tomson, PL, 2016)
"Teeth with failure of the root canal treatment and apical periodontitis, and consequently with high levels of bacteria, PIC, and MMP, may present a better prognosis after a 30 days of a calcium hydroxide-based ICM."	( Arruda-Vasconcelos, R; Barbosa-Ribeiro, M; de Almeida, JFA; de-Jesus-Soares, A; Ferraz, CCR; Gomes, BPFA; Zaia, AA, 2019)
"Sixteen patients with post-treatment apical periodontitis were allocated into two groups according to the intracanal medicament used: calcium hydroxide (CH) and 2% chlorhexidine gluconate gel (CHX) group."	( Ersahan, S; Hepsenoglu, YE, 2023)
"We report the treatment of periapical periodontitis and tooth preservation in a 41-year-old Japanese woman previously diagnosed with ossification of the posterior longitudinal ligament."	( Higashi, T; Ishibashi, Y; Nagata, K; Oosio, T; Tsuru, M; Wada, K, 2022)
"Twenty patients with post-treatment apical periodontitis were allocated into two groups according to the irrigation activation method used: XPF and EA group."	( Ersahan, S; Hepsenoglu, YE, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	33 (5.28)	23.3326
1990's	77 (12.32)	12.5806
2000's	156 (24.96)	18.1394
2010's	266 (42.56)	28.8240
2020's	93 (14.88)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	1	0
acetic acid	low	1	0
adenine	low	3	0
citric acid, anhydrous	medium	7	1
cytosine	medium	3	1
lactic acid	low	1	0
dimethyl sulfoxide	low	1	0
formaldehyde	low	8	0
glycerol	medium	3	1
iodine	medium	3	1
thioctic acid	low	2	0
melatonin	low	5	0
nickel	medium	20	6
nitrites	low	1	0
hydroxide ion	low	1	0
oxalic acid	low	1	0
phosphoric acid	medium	1	1
thiosulfates	low	1	0
thymine	medium	4	1
acetaminophen	medium	3	3
alendronate	low	2	0
pimagedine	low	1	0
aspirin	low	2	0
berberine	low	3	0
bupivacaine	medium	1	1
caffeine	low	1	0
beta-glycerophosphoric acid	low	2	0
camphor, (+-)-isomer	medium	13	1
cefixime	low	1	0
cetyltrimethylammonium ion	low	1	0
ciprofloxacin	medium	23	2
clotrimazole	low	1	0
dequalinium	low	1	0
diclofenac	low	1	0
etidronate	medium	2	1
etodolac	medium	1	1
fluconazole	low	1	0
flucytosine	low	1	0
gentamicin	low	1	0
glutaral	low	1	0
glyphosate	low	1	0
haloperidol	medium	32	5
ibuprofen	medium	13	11
lidocaine	medium	2	2
indomethacin	low	1	0
ketorolac	medium	2	2
metformin	low	3	0
methenamine	medium	3	1
metronidazole	medium	29	3
miconazole	low	1	0
nifedipine	low	1	0
ofloxacin	low	2	0
omeprazole	low	1	0
4-chlorophenol	low	1	0
potassium chloride	medium	4	1
potassium iodide	medium	5	2
propidium	low	2	0
resorcinol	low	1	0
rofecoxib	medium	1	1
risedronic acid	low	1	0
tinidazole	medium	2	2
tolmetin	medium	1	1
mitomycin	low	1	0
prednisone	low	2	0
penicillin g	medium	1	1
glutamine	low	1	0
sucrose	low	1	0
2,3,4,6-tetrachlorophenol	medium	13	1
edetic acid	medium	24	6
methylene blue	medium	6	2
egtazic acid	low	1	0
chloroform	low	1	0
ampicillin	low	3	0
arginine	low	2	0
iodoform	medium	4	2
triamcinolone acetonide	medium	7	2
tromethamine	medium	1	1
isoprene	low	1	0
methylprednisolone	medium	3	2
penicillin v	medium	5	2
thymol	low	5	0
tolonium chloride	low	1	0
phenothiazine	low	1	0
acrolein	low	1	0
pentane	low	1	0
framycetin	medium	2	1
catechin	low	2	0
acridines	low	1	0
limestone	low	1	0
fusarium	low	1	0
eosine yellowish-(ys)	low	1	0
gentian violet	low	1	0
lithium carbonate	low	1	0
acetylcysteine	low	2	0
erythromycin	medium	2	1
homoserine	low	1	0
norflurane	medium	1	1
calcium citrate	low	1	0
durapatite	low	8	0
zinc oxide	medium	22	4
bisphenol a-glycidyl methacrylate	low	3	0
diallyl disulfide	low	1	0
neodymium	medium	4	1
silver	medium	12	2
technetium	low	2	0
titanium	medium	31	8
yttrium	low	1	0
zirconium	medium	4	1
barium sulfate	low	5	0
calcium phosphate, dibasic, anhydrous	low	2	0
calcium phosphate, monobasic, anhydrous	low	2	0
tricalcium phosphate	low	6	0
sodium thiosulfate	low	1	0
calcium sulfate	medium	3	1
zinc phosphate	low	1	0
ozone	medium	4	3
tricalcium silicate	low	2	0
iodine	low	2	0
cetylpyridinium chloride anhydrous	low	1	0
azides	low	1	0
amoxicillin	medium	10	1
nigericin	low	1	0
substance p	medium	4	2
10-carboxymethyl-9-acridanone	low	1	0
cefmetazole	low	1	0
propiconazole	low	1	0
cefaclor anhydrous	low	2	0
fenoxycarb	low	1	0
simvastatin	low	4	0
raloxifene hydrochloride	low	2	0
glucose, (beta-d)-isomer	low	1	0
epigallocatechin gallate	low	2	0
pyrrolidine dithiocarbamate	low	1	0
cephalosporin c	low	3	0
1,7-phenanthroline	low	1	0
fluorodeoxyglucose f18	low	1	0
zoledronic acid	low	1	0
camphorated parachlorophenol	medium	11	1
1,10-phenanthroline-5,6-dione	low	1	0
oxazolidin-2-one	medium	2	1
c.i. direct red 80	low	1	0
rosiglitazone	low	1	0
ketorolac tromethamine	medium	1	1
clarithromycin	low	1	0
nicotine	low	1	0
fibrinogen	low	2	0
n2 dental cement	low	4	0
c & b metabond	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	medium	1	1
methotrexate	low	1	0
sulbactam	low	1	0
moxifloxacin	low	1	0
calcium pyrophosphate	low	2	0
camphorated phenol	low	1	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	low	1	0
lithium chloride	low	1	0
fibrin	medium	2	1
inositol 3-phosphate	low	4	0
cefoxitin	low	1	0
pentazocine	medium	1	1
bacampicillin	low	2	0
linezolid	medium	2	1
sultamicillin	low	1	0
arachidonic acid	low	1	0
resveratrol	low	1	0
tacrolimus	low	1	0
eicosapentaenoic acid	low	1	0
clindamycin	medium	5	2
fosfomycin	low	1	0
zithromax	low	2	0
sodium bicarbonate	medium	4	1
bromochloroacetic acid	low	2	0
cinnamaldehyde	low	1	0
dimethyl fumarate	low	1	0
leuprolide	low	1	0
curcumin	low	1	0
capsaicin	low	1	0
5-cyano-2,3-ditolyltetrazolium chloride	low	1	0
stattic	low	3	0
lincomycin	medium	1	1
propidium monoazide	low	1	0
oxalylglycine	low	1	0
nitinol	low	2	0
sodium dodecyl sulfate	low	1	0
l 663536	low	1	0
osteoprotegerin	low	31	0
cathepsin g	low	1	0
dinoprostone	low	10	0
leukotriene b4	low	2	0
leukotriene c4	low	1	0
amphotericin b	low	1	0
thromboxane b2	low	1	0
codeine	medium	1	1
phenylephrine hydrochloride	low	1	0
naloxone	medium	1	1
bay 11-7082	low	1	0
barium	low	1	0
bismuth	medium	20	2
sulfur	low	1	0
phosphorus	low	2	0
phytochlorin	medium	1	1
pregabalin	low	1	0
selenium	low	1	0
tytin	low	1	0
cinmethacin	low	1	0
nitrocefin	low	2	0
demycarosylturimycin h	low	1	0
chlorhexidine	medium	80	32
amoxicillin-potassium clavulanate combination	low	4	0
aluminum oxide	low	1	0
odanacatib	low	1	0
dimethylarginine	low	2	0
5s,12r,18r-trihydroxy-6z,8e,10e,14z,16e-eicosapentaenoic acid	low	2	0
resolvin d2	low	1	0
virginiamycin	low	2	0
acid phosphatase	low	11	0
jaw	low	6	0
4-aminobenzoyl-glycyl-prolyl-leucyl-alanine hydroxamic acid	low	1	0
chitosan	low	2	0
sodium hypochlorite	medium	133	36
quinupristin	low	1	0
quinupristin-dalfopristin	low	1	0
interleukin-8	medium	9	1
vasoactive intestinal peptide	medium	3	1
dimethylaminododecyl methacrylate	low	2	0
ascorbic acid	low	1	0
tetracycline	low	3	0
minocycline	medium	17	2
methacycline	medium	1	1
salicylates	medium	9	1
warfarin	low	2	0
metastat	low	1	0
demeclocycline	medium	7	2
ledermix	medium	7	2
epidermal growth factor	low	1	0
gluma	low	1	0
transforming growth factor beta	medium	9	1
glutaminase	low	1	0
caseins	low	1	0
hyaluronoglucosaminidase	low	1	0
adrenomedullin	low	3	0
dalfopristin	low	1	0
talwin nx	medium	1	1
cyclosporine	low	1	0
technetium tc 99m medronate	medium	2	1
exudates	low	2	0
deoxyguanosine	low	1	0
guanine	low	3	0
dacarbazine	low	1	0
pemetrexed	low	1	0
8-hydroxy-2'-deoxyguanosine	low	1	0
cyclic guanosine monophosphate-adenosine monophosphate	low	1	0
lipoteichoic acid	low	13	0
formocresol	medium	6	1

Protein Targets (1,717)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
PAX8	0	0	0	2
glp-1 receptor, partial	13	0	0	13
WRN	1	0	0	1
MSRA protein	0	0	1	1
TDP1 protein	58	0	0	58
Phospholipase C, gamma 1	0	1	0	1
Phospholipase C, beta 3 (phosphatidylinositol-specific)	0	1	0	1
Smad3	11	0	0	11
apical membrane antigen 1, AMA1	9	0	0	9
67.9K protein	16	0	0	16
photoreceptor-specific nuclear receptor	0	2	0	2
green fluorescent protein, partial	0	1	0	1
IDH1	23	0	0	23
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	8	0	0	8
serine/threonine-protein kinase PLK1	8	0	0	8
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Vpr	5	0	0	5
Rap guanine nucleotide exchange factor 3	4	0	0	4
Coagulation factor XII	0	1	0	1
Cholinesterase	0	10	0	10
Acetylcholinesterase	0	17	0	17
Liver carboxylesterase 1	0	1	0	1
Alpha-synuclein	9	4	1	14
RNA-editing ligase 1, mitochondrial	0	1	0	1
TAR DNA-binding protein 43	21	0	0	21
Rap guanine nucleotide exchange factor 4	6	0	0	6
putative polyprotein	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	30	0	0	30
geminin	54	0	0	54
lamin isoform A-delta10	45	0	0	45
Guanine nucleotide-binding protein G	8	0	0	8
Chain A, Putative fructose-1,6-bisphosphate aldolase	15	0	0	15
Chain A, Ferritin light chain	15	0	0	15
acid sphingomyelinase	6	0	0	6
thioredoxin reductase	28	0	0	28
hypoxia-inducible factor 1 alpha subunit	29	0	0	29
SMAD family member 2	22	0	0	22
SMAD family member 3	22	0	0	22
GLI family zinc finger 3	60	0	0	60
AR protein	72	0	0	72
estrogen receptor 2 (ER beta)	27	0	0	27
nuclear receptor subfamily 1, group I, member 3	38	0	0	38
progesterone receptor	35	0	0	35
glucocorticoid receptor [Homo sapiens]	49	0	0	49
retinoic acid nuclear receptor alpha variant 1	60	0	0	60
retinoid X nuclear receptor alpha	43	0	0	43
farnesoid X nuclear receptor	39	0	0	39
estrogen nuclear receptor alpha	89	0	0	89
G	22	0	0	22
glucocerebrosidase	9	0	0	9
peroxisome proliferator-activated receptor delta	37	0	0	37
peroxisome proliferator activated receptor gamma	46	0	0	46
vitamin D (1,25- dihydroxyvitamin D3) receptor	35	0	0	35
alpha-galactosidase	7	0	0	7
euchromatic histone-lysine N-methyltransferase 2	55	0	0	55
activating transcription factor 6	20	0	0	20
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	23	0	0	23
v-jun sarcoma virus 17 oncogene homolog (avian)	33	0	0	33
Stimulator of interferon genes protein	0	0	1	1
chromobox protein homolog 1	32	0	0	32
thyroid hormone receptor beta isoform 2	52	0	0	52
heat shock protein beta-1	24	0	0	24
importin subunit beta-1 isoform 1	9	0	0	9
flap endonuclease 1	20	0	0	20
snurportin-1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	58	0	0	58
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
peripheral myelin protein 22	26	0	0	26
Trypsin	0	2	0	4
Interferon beta	27	0	0	27
HLA class I histocompatibility antigen, B alpha chain	22	0	0	22
Cellular tumor antigen p53	52	0	0	52
Stimulator of interferon genes protein	0	0	3	3
Inositol hexakisphosphate kinase 1	22	0	0	22
cytochrome P450 2C9, partial	22	0	0	22
Chain A, HADH2 protein	27	0	0	27
Chain B, HADH2 protein	27	0	0	27
Luciferase	31	0	0	31
interleukin 8	19	0	0	19
RAR-related orphan receptor gamma	56	0	0	56
thyroid stimulating hormone receptor	25	0	0	25
estrogen-related nuclear receptor alpha	64	0	0	64
pregnane X nuclear receptor	43	0	0	43
aryl hydrocarbon receptor	34	0	0	34
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	39	0	0	39
Histone H2A.x	21	0	0	21
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	22	0	0	22
mitogen-activated protein kinase 1	19	0	0	19
Voltage-dependent calcium channel gamma-2 subunit	32	0	0	32
Glutamate receptor 2	33	0	0	33
Nuclear receptor ROR-gamma	26	0	0	26
Peroxisome proliferator-activated receptor alpha	2	2	1	5
ATPase family AAA domain-containing protein 5	22	0	0	22
Ataxin-2	27	0	0	27
Oxysterols receptor LXR-beta	0	1	1	2
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
ATAD5 protein, partial	17	0	0	17
GLS protein	24	0	0	24
Microtubule-associated protein tau	30	0	0	31
aldehyde dehydrogenase 1 family, member A1	44	0	0	44
EWS/FLI fusion protein	30	0	0	31
cytochrome P450 3A4 isoform 1	31	0	0	31
Gamma-aminobutyric acid receptor subunit pi	31	5	0	36
ATP-binding cassette sub-family C member 3	0	39	0	39
Multidrug resistance-associated protein 4	0	39	0	41
Solute carrier family 22 member 6	0	7	0	7
Carbonic anhydrase 12	0	5	0	5
UDP-glucuronosyltransferase 1A9	0	2	0	5
Bile salt export pump	0	6	0	6
Bile salt export pump	0	55	0	55
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	18	0	19
Carbonic anhydrase 2	0	21	2	24
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	11	0	13
Prostaglandin G/H synthase 1	0	11	3	15
Carbonic anhydrase 3	0	4	0	4
Cytochrome P450 3A4	0	24	3	31
Cytochrome P450 2D6	0	9	0	10
Cytochrome P450 2C9	0	21	3	26
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	31	5	0	36
Sulfotransferase 1A1	0	0	0	2
Gamma-aminobutyric acid receptor subunit delta	31	5	0	36
Gamma-aminobutyric acid receptor subunit gamma-2	31	5	1	37
UDP-glucuronosyltransferase 1-6	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	31	5	0	36
Gamma-aminobutyric acid receptor subunit alpha-3	31	5	0	36
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	3	0	4
Carbonic anhydrase 4	0	11	0	11
Prostaglandin G/H synthase 1	0	15	0	15
Carbonic anhydrase 6	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	31	5	0	36
Gamma-aminobutyric acid receptor subunit alpha-2	31	5	0	36
Gamma-aminobutyric acid receptor subunit alpha-4	31	5	0	36
Gamma-aminobutyric acid receptor subunit gamma-3	31	5	0	36
Gamma-aminobutyric acid receptor subunit alpha-6	31	5	0	36
Carbonic anhydrase 5A, mitochondrial	0	7	0	7
Prostaglandin G/H synthase 2	0	20	2	24
Carbonic anhydrase 7	0	4	0	4
Cytochrome P450 2J2	0	11	0	11
Gamma-aminobutyric acid receptor subunit alpha-1	31	7	1	39
Gamma-aminobutyric acid receptor subunit beta-3	31	5	0	36
Gamma-aminobutyric acid receptor subunit beta-2	31	5	1	37
Carbonic anhydrase 9	0	10	1	11
GABA theta subunit	31	5	0	36
Canalicular multispecific organic anion transporter 1	0	37	0	37
Carbonic anhydrase 15	0	7	0	7
Carbonic anhydrase 13	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	31	5	0	36
Carbonic anhydrase 14	0	5	0	5
Carbonic anhydrase 5B, mitochondrial	0	5	0	5
toxin B	0	0	0	1
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	1	1	2
Tyrosine-protein kinase Fyn	0	3	1	4
Fibrinogen C domain-containing protein 1	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	15	0	0	15
Chain A, 2-oxoglutarate Oxygenase	28	0	0	28
Chain A, ATP-DEPENDENT DNA HELICASE Q1	11	0	0	11
acetylcholinesterase	23	0	0	23
dopamine D1 receptor	5	0	0	5
15-lipoxygenase, partial	17	0	0	17
pregnane X receptor	11	0	0	11
phosphopantetheinyl transferase	26	0	0	26
USP1 protein, partial	24	0	0	24
NFKB1 protein, partial	8	0	0	8
Thrombopoietin	5	0	0	5
regulator of G-protein signaling 4	20	0	0	20
arylsulfatase A	15	0	0	15
Bloom syndrome protein isoform 1	21	0	0	21
D(1A) dopamine receptor	9	0	0	9
thyroid hormone receptor beta isoform a	22	0	0	22
survival motor neuron protein isoform d	17	0	0	17
muscarinic acetylcholine receptor M1	12	0	0	12
Histone deacetylase 3	0	4	0	4
Histone deacetylase 4	0	4	0	4
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	4	0	4
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	4	0	4
Histone deacetylase 11	0	4	0	4
Histone deacetylase 8	0	5	0	5
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	4	0	4
Histone deacetylase 5	0	4	0	4
ATP-dependent phosphofructokinase	28	0	0	28
DNA polymerase iota isoform a (long)	25	0	0	25
DNA topoisomerase 2-alpha	0	1	0	6
Transient receptor potential cation channel subfamily A member 1	0	1	7	9
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	30	0	0	30
nuclear factor erythroid 2-related factor 2 isoform 2	17	0	0	17
tumor susceptibility gene 101 protein	2	0	0	2
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	2	0	2
Xanthine dehydrogenase/oxidase	0	3	0	3
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	5	0	6
Farnesyl pyrophosphate synthase	0	6	0	6
Hypoxanthine-guanine phosphoribosyltransferase	0	1	0	1
Farnesyl pyrophosphate synthase	0	5	0	5
Farnesyl pyrophosphate synthase	0	3	0	3
Chain A, Beta-lactamase	13	0	0	13
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	4
Beta-lactamase	0	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
DNA polymerase eta isoform 1	7	0	0	7
urokinase-type plasminogen activator precursor	11	0	0	11
plasminogen precursor	11	0	0	11
urokinase plasminogen activator surface receptor precursor	11	0	0	11
DNA polymerase kappa isoform 1	24	0	0	24
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	1	0	3
Beta-lactamase	0	1	0	5
Kappa-type opioid receptor	0	5	1	8
Solute carrier family 15 member 1	0	9	0	9
Solute carrier family 15 member 1	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Chain A, Cruzipain	12	0	0	12
tumor necrosis factor	4	0	0	4
vitamin D3 receptor isoform VDRA	29	0	0	29
Cytochrome P450 2C19	0	7	0	9
Potassium voltage-gated channel subfamily H member 2	0	18	0	20
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	6	0	7
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	3
Metallo-beta-lactamase VIM-11	0	0	0	4
Metallo-beta-lactamase VIM-2	0	0	0	4
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
DNA polymerase beta	12	0	0	12
60 kDa heat shock protein, mitochondrial	0	6	0	6
Beta-lactamase OXA-7	0	0	0	2
Spike glycoprotein	28	0	0	28
10 kDa heat shock protein, mitochondrial	0	6	0	6
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	1	0	3
Thiosulfate sulfurtransferase	0	6	0	6
Metallo-beta-lactamase VIM-13	0	1	0	3
Efflux transporter	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	3
Class D beta-lactamase	0	1	0	3
60 kDa chaperonin	0	6	0	6
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
Beta-lactamase	0	0	0	3
10 kDa chaperonin	0	6	0	6
Metallo-b-lactamase	0	0	0	5
Carbapenem-hydrolyzing beta-lactamase KPC	0	1	0	5
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	0	5
Beta-lactamase VIM-1	0	1	0	3
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	21	0	0	21
thioredoxin glutathione reductase	8	0	0	8
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	13	0	0	13
cellular tumor antigen p53 isoform a	14	0	0	14
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
nuclear receptor ROR-gamma isoform 1	31	0	0	31
lethal(3)malignant brain tumor-like protein 1 isoform I	4	0	0	4
histone acetyltransferase KAT2A isoform 1	16	0	0	16
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	2	0	6
caspase-1 isoform alpha precursor	5	0	0	5
Fatty-acid amide hydrolase 1	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	17	0	0	17
Prostaglandin G/H synthase 1	0	6	0	8
Coagulation factor VII	0	2	0	2
60 kDa chaperonin	0	5	0	5
Aromatase	0	8	0	8
Tissue factor	0	3	0	3
Fatty acid-binding protein, adipocyte	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Histamine H2 receptor	21	0	0	22
Calmodulin	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	1	0	4
Prostaglandin G/H synthase 2	0	10	0	11
Solute carrier organic anion transporter family member 2A1	0	0	0	3
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Lanosterol 14-alpha demethylase	0	6	1	7
Solute carrier organic anion transporter family member 1B3	0	5	0	6
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	2	1	3
Solute carrier organic anion transporter family member 1B1	0	7	0	7
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
cytochrome P450 2C19 precursor	7	0	0	7
lethal factor (plasmid)	16	0	0	16
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	2	0	3
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	3	0	4
Nitric oxide synthase, inducible	0	1	1	4
Cationic amino acid transporter 3	0	1	0	1
Chain A, Hyaluronidase, phage associated	0	1	0	1
Polyphenol oxidase 2	0	6	0	9
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	3	1	5
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	4	0	4
Alpha-2B adrenergic receptor	0	8	1	9
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	1	0	2
Egl nine homolog 1	0	2	1	4
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	2	0	3
Solute carrier family 23 member 1	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	7	0	0	7
cytochrome P450 2D6	26	0	0	26
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 2	0	4	0	5
Epidermal growth factor receptor	0	6	0	6
Fatty acid-binding protein, liver	0	5	0	5
Integrin beta-3	13	1	0	14
Myeloperoxidase	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Integrin alpha-IIb	13	1	0	14
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	1	8	0	10
Adenosine receptor A2a	0	8	0	10
Substance-P receptor	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	2	0	2
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	5	1	6
Sigma non-opioid intracellular receptor 1	0	3	1	4
Carbonic anhydrase	0	4	0	4
Fumarate hydratase	14	0	0	14
polyprotein	14	0	0	14
Parkin	9	0	0	9
Replicase polyprotein 1ab	0	2	0	2
NPC intracellular cholesterol transporter 1 precursor	5	0	0	5
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
ras-related protein Rab-9A	8	0	0	8
serine/threonine-protein kinase mTOR isoform 1	7	0	0	7
Amyloid-beta precursor protein	3	5	1	10
Replicase polyprotein 1ab	0	10	2	12
Nuclear factor NF-kappa-B p105 subunit	0	3	0	3
Nuclear factor NF-kappa-B p100 subunit	0	3	0	3
Transcription factor p65	0	3	0	3
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Class A sortase SrtA	0	1	0	1
PPM1D protein	8	0	0	8
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	15	0	0	15
cytochrome P450 2D6 isoform 1	10	0	0	10
Telomerase reverse transcriptase	0	2	0	2
Acetylcholinesterase	0	6	0	6
Lysine-specific histone demethylase 1A	0	5	0	5
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	3
Aldo-keto reductase family 1 member C3	0	4	0	4
Prolyl endopeptidase	0	2	0	2
Aldo-keto reductase family 1 member C2	0	2	0	2
Cholinesterase	0	5	0	5
Inositol monophosphatase 1	13	0	0	13
Cytochrome P450 1B1	0	6	0	6
Eyes absent homolog 2	0	2	0	2
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
Chain A, Estrogen-related receptor gamma	0	0	1	1
GALC protein	3	0	0	3
caspase 7, apoptosis-related cysteine protease	14	0	0	14
caspase-3	14	0	0	14
thyroid stimulating hormone receptor	24	0	0	24
potassium voltage-gated channel subfamily H member 2 isoform d	15	0	0	15
GTPase KRas	0	0	1	1
Estrogen receptor	0	6	1	7
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	5	0	5
Aldo-keto reductase family 1 member B1	0	15	0	15
Androgen receptor	0	3	1	4
Androgen receptor	0	11	0	11
Sodium-dependent noradrenaline transporter	0	14	3	17
Sodium-dependent serotonin transporter	0	8	0	8
5-hydroxytryptamine receptor 6	0	7	0	7
Estrogen-related receptor gamma	0	1	0	1
Sodium-dependent dopamine transporter	0	10	0	10
GTP-binding protein Rheb	0	0	1	1
Estrogen receptor beta	0	4	1	5
TSHR protein	2	0	0	2
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	3	5
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	6	1	7
Adenosine receptor A3	0	11	0	11
Amine oxidase [flavin-containing] A	0	9	0	9
Amine oxidase [flavin-containing] B	0	8	0	8
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2a	0	9	1	11
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	8	1	11
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	2	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	2	4
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	2
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	1	0	2
transient receptor potential cation channel subfamily V member 1	2	0	0	2
Transient receptor potential cation channel subfamily V member 1	0	3	1	4
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	6	0	6
Cannabinoid receptor 1	0	6	0	6
Cannabinoid receptor 2	0	2	0	2
D(2) dopamine receptor	0	2	2	4
Potassium voltage-gated channel subfamily A member 1	0	2	1	3
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	1	1	2
peripheral myelin protein 22 isoform 1	12	0	0	12
neuropeptide S receptor isoform A	8	0	0	8
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	1	2
Sucrase-isomaltase, intestinal	0	2	0	2
Mu-type opioid receptor	0	15	4	22
Delta-type opioid receptor	0	10	2	15
Kappa-type opioid receptor	0	13	3	19
Melatonin receptor type 1A	0	2	2	4
Melatonin receptor type 1B	0	2	2	4
Death-associated protein kinase 1	0	1	0	1
Beta-secretase 1	0	3	0	3
Carbonic anhydrase 3	0	4	0	4
Dihydroorotate dehydrogenase	0	2	0	2
bromodomain adjacent to zinc finger domain 2B	14	0	0	14
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
streptokinase A precursor	0	0	10	10
Estrogen receptor	0	1	4	5
Estrogen receptor beta	0	1	4	5
Solute carrier family 22 member 8	0	4	0	7
Solute carrier family 22 member 8	0	4	0	5
Insulin-degrading enzyme	0	1	0	1
Metallo-beta-lactamase VIM-19	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
BlaVIM-1	0	0	0	2
thyrotropin-releasing hormone receptor	7	0	0	7
Caspase-2	0	0	1	1
interferon gamma precursor	0	0	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	6	1	7
30S ribosomal protein S7	0	6	1	7
50S ribosomal protein L15	0	6	1	7
50S ribosomal protein L10	0	6	1	7
50S ribosomal protein L11	0	6	1	7
50S ribosomal protein L7/L12	0	6	1	7
50S ribosomal protein L19	0	6	1	7
50S ribosomal protein L1	0	6	1	7
50S ribosomal protein L20	0	6	1	7
50S ribosomal protein L27	0	6	1	7
50S ribosomal protein L28	0	6	1	7
50S ribosomal protein L29	0	6	1	7
50S ribosomal protein L31	0	6	1	7
50S ribosomal protein L31 type B	0	6	1	7
50S ribosomal protein L32	0	6	1	7
50S ribosomal protein L33	0	6	1	7
50S ribosomal protein L34	0	6	1	7
50S ribosomal protein L35	0	6	1	7
50S ribosomal protein L36	0	6	1	7
30S ribosomal protein S10	0	6	1	7
30S ribosomal protein S11	0	6	1	7
30S ribosomal protein S12	0	6	1	7
30S ribosomal protein S13	0	6	1	7
30S ribosomal protein S16	0	6	1	7
30S ribosomal protein S18	0	6	1	7
30S ribosomal protein S19	0	6	1	7
30S ribosomal protein S20	0	6	1	7
30S ribosomal protein S2	0	6	1	7
30S ribosomal protein S3	0	6	1	7
30S ribosomal protein S4	0	6	1	7
30S ribosomal protein S5	0	6	1	7
30S ribosomal protein S8	0	6	1	7
30S ribosomal protein S9	0	6	1	7
50S ribosomal protein L13	0	6	1	7
50S ribosomal protein L14	0	6	1	7
50S ribosomal protein L16	0	6	1	7
50S ribosomal protein L23	0	6	1	7
30S ribosomal protein S15	0	6	1	7
50S ribosomal protein L17	0	6	1	7
50S ribosomal protein L21	0	6	1	7
50S ribosomal protein L30	0	6	1	7
50S ribosomal protein L6	0	6	1	7
30S ribosomal protein S14	0	6	1	7
30S ribosomal protein S17	0	6	1	7
30S ribosomal protein S1	0	6	1	7
50S ribosomal protein L18	0	6	1	7
50S ribosomal protein L2	0	6	1	7
50S ribosomal protein L3	0	6	1	7
50S ribosomal protein L24	0	6	1	7
50S ribosomal protein L4	0	6	1	7
50S ribosomal protein L22	0	6	1	7
50S ribosomal protein L5	0	6	1	7
30S ribosomal protein S21	0	6	1	7
50S ribosomal protein L25	0	6	1	7
50S ribosomal protein L36 2	0	6	1	7
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
PINK1	3	0	0	3
heat shock protein 90	0	0	3	3
calcineurin A1, putative	0	0	3	3
hepatocyte nuclear factor 4-alpha isoform 2	0	2	0	2
cytochrome P450 2C9 precursor	9	0	0	9
perilipin-5	0	4	0	4
perilipin-1	0	4	0	4
transcriptional regulator ERG isoform 3	6	0	0	6
huntingtin isoform 2	11	0	0	11
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	6	0	1	7
protein AF-9 isoform a	0	0	0	2
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	2
bcl-2-related protein A1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	4	0	4
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	2	2
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 1	0	6	0	9
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Glutathione reductase, mitochondrial	0	4	0	6
72 kDa type IV collagenase	0	4	0	4
Matrix metalloproteinase-9	0	4	0	4
Trypanothione reductase	0	1	0	1
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Multidrug and toxin extrusion protein 1	0	7	0	7
Spermine oxidase	0	1	0	1
shiga toxin 1 variant A subunit	1	0	0	1
shiga toxin 1 B subunit	1	0	0	1
Cell division protein FtsZ	0	1	0	3
Transient receptor potential cation channel subfamily A member 1	0	0	3	3
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	2	0	3
DNA gyrase subunit A	0	4	0	8
DNA gyrase subunit B	0	4	0	8
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	2	0	3
DNA gyrase subunit A	0	2	0	3
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	3	0	5
DNA gyrase subunit A	0	3	0	5
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	2	0	2
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	3	0	3
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	3	0	3
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
ATP-dependent translocase ABCB1	0	17	0	19
Protein-arginine deiminase type-4	0	6	0	6
endonuclease IV	4	0	0	4
isocitrate dehydrogenase 1, partial	2	0	0	2
nonstructural protein 1	9	0	0	9
pyruvate kinase	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	11	0	0	11
Caspase-7	3	0	0	3
beta-2 adrenergic receptor	2	0	1	3
caspase-3	3	0	0	3
heat shock protein HSP 90-alpha isoform 2	0	1	0	5
M-phase phosphoprotein 8	10	0	0	10
Intermediate conductance calcium-activated potassium channel protein 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
5-hydroxytryptamine receptor 4	0	10	0	10
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Chymotrypsinogen A	0	5	0	5
Beta-lactamase	0	4	0	4
Glucocorticoid receptor	0	12	2	19
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	3	0	3
Histidine-rich protein PFHRP-II	0	1	0	1
Heme oxygenase 1	0	5	0	5
ATP-dependent translocase ABCB1	0	8	0	8
Epoxide hydrolase 1	0	0	0	2
Glycine receptor subunit alpha-1	0	12	0	12
Muscarinic acetylcholine receptor M2	0	8	0	9
Muscarinic acetylcholine receptor M4	0	7	0	8
Beta-1 adrenergic receptor	0	4	0	4
Alpha-2A adrenergic receptor	0	9	1	10
Muscarinic acetylcholine receptor M1	0	8	0	9
Beta-3 adrenergic receptor	0	4	0	4
D(2) dopamine receptor	0	8	1	11
Alpha-1B adrenergic receptor	0	15	0	15
Potassium-transporting ATPase subunit beta	0	2	0	2
Potassium-transporting ATPase alpha chain 1	0	2	0	2
5-hydroxytryptamine receptor 1A	0	7	0	8
Muscarinic acetylcholine receptor M3	0	7	0	8
Glycine receptor subunit beta	0	12	0	12
ATP-dependent translocase ABCB1	0	8	0	8
Substance-K receptor	0	8	0	8
D(1A) dopamine receptor	0	8	0	9
D(4) dopamine receptor	0	6	1	9
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Glycine receptor subunit alpha-2	0	12	0	12
Heme oxygenase 2	0	5	0	5
Glycine receptor subunit alpha-3	0	12	0	12
Thromboxane-A synthase	0	5	0	5
Histamine H2 receptor	0	8	0	8
C-X-C chemokine receptor type 1	0	2	0	2
Alpha-1D adrenergic receptor	0	8	0	8
Substance-P receptor	0	6	1	7
Platelet-activating factor receptor	0	2	0	3
5-hydroxytryptamine receptor 2A	0	8	0	8
5-hydroxytryptamine receptor 2C	0	10	0	10
5-hydroxytryptamine receptor 1B	0	5	0	5
Indoleamine 2,3-dioxygenase 1	0	4	0	4
Vasopressin V2 receptor	0	1	0	1
Histamine H1 receptor	0	4	0	4
D(3) dopamine receptor	0	8	1	11
Malate dehydrogenase, cytoplasmic	0	3	0	3
5-hydroxytryptamine receptor 2B	0	6	0	6
Alpha-1A adrenergic receptor	0	16	0	16
C-C chemokine receptor type 4	0	1	0	1
Transitional endoplasmic reticulum ATPase	0	1	0	1
Cytochrome P450 144	0	0	3	3
Steroid C26-monooxygenase	0	0	3	3
Cytochrome P450 130	0	0	1	1
Cytochrome P450 130	0	0	1	1
Steroid C26-monooxygenase	0	0	3	3
Mycocyclosin synthase	0	0	3	3
Lanosterol 14-alpha demethylase	0	0	3	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	8
Nuclear receptor subfamily 1 group I member 3	0	2	0	2
Sterol 14-alpha demethylase	0	0	2	2
Indoleamine 2,3-dioxygenase 2	0	3	0	3
Bile acid receptor	0	1	0	1
14-alpha sterol demethylase	0	0	2	2
Cysteinyl leukotriene receptor 1	0	2	1	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	4
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	3	0	8
Delta-type opioid receptor	0	5	1	8
Kappa-type opioid receptor	0	4	1	7
Mu-type opioid receptor	0	4	1	8
Cytochrome P450 2D4	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	3	3
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Nrf2	2	0	0	2
alkaline phosphatase, intestinal	0	1	0	1
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
lysosomal alpha-glucosidase preproprotein	6	0	0	6
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
hemoglobin subunit beta	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
intestinal alkaline phosphatase precursor	0	1	0	1
pyruvate kinase PKM isoform a	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	8	0	0	8
muscleblind-like protein 1 isoform 1	11	0	0	11
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Prostaglandin E synthase	0	4	0	4
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Microtubule-associated protein tau	0	5	1	7
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Alpha-1D adrenergic receptor	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Proteasome subunit beta type-5	0	2	0	2
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Glycogen synthase kinase-3 beta	0	2	1	3
Caspase-7	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Lactoylglutathione lyase	0	3	0	3
Histone acetyltransferase p300	0	2	0	2
Serine/threonine-protein kinase PAK 1	0	3	0	3
5-hydroxytryptamine receptor 4	0	1	1	2
Sodium/bile acid cotransporter	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	3	5
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Interferon regulatory factor 3	0	0	1	1
Stimulator of interferon genes protein	0	1	2	3
Deoxycytidine kinase	0	0	0	1
Isocitrate lyase	0	1	0	1
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Thymidine kinase, cytosolic	0	1	0	2
Deoxycytidine kinase	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
D(1A) dopamine receptor	4	1	0	5
Single-stranded DNA cytosine deaminase	1	0	0	1
Fatty acid synthase	0	2	0	2
Aldo-keto reductase family 1 member B10	0	1	0	1
Dihydrofolate reductase	0	8	0	10
Cytochrome c oxidase subunit 2	0	3	0	3
Transthyretin	0	0	3	5
Albumin	0	5	8	13
Interleukin-8	0	3	0	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	0	1
Fatty acid-binding protein, intestinal	0	3	1	4
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	4
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Prostaglandin G/H synthase 2	0	5	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	3
UDP-glucuronosyltransferase 2B10	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Prostaglandin G/H synthase 2	0	4	0	5
Solute carrier family 22 member 6	0	4	0	6
Prostaglandin G/H synthase 1	0	5	0	6
Carbonic anhydrase 4	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Kelch-like ECH-associated protein 1	0	0	1	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Solute carrier family 22 member 11	0	0	0	3
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	2	1	3
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Angiotensin-converting enzyme	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	2	4	7
Oxoeicosanoid receptor 1	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	2	0	2
galactokinase	1	0	0	1
POsterior Segregation	0	0	3	3
Polycomb protein EED	0	0	1	1
NAD kinase	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
Tissue-type plasminogen activator	0	1	0	1
Polymerase acidic protein	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Neutrophil elastase	0	2	0	2
Hepatocyte growth factor receptor	0	2	0	2
Matrilysin	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Apoptosis regulator Bcl-2	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
CPG DNA methylase	0	1	0	1
Lethal factor	0	2	0	2
Phosphoglycerate mutase 1	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Dipeptidyl peptidase 4	0	4	0	4
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Fatty acid synthase	0	3	0	3
Matrix metalloproteinase-14	0	2	0	2
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
BH3-interacting domain death agonist	0	1	0	1
Lactoperoxidase	0	0	0	1
Bcl-2-like protein 1	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Mitogen-activated protein kinase 14	0	2	0	2
Bcl-2-related protein A1	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	5	0	5
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
MAP kinase-activated protein kinase 5	0	1	0	1
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
Zinc finger protein mex-5	0	0	3	3
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
unnamed protein product	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Lanosterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
likely tRNA 2'-phosphotransferase	0	1	0	1
Skn7p	0	0	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0	1	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	2	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	2	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	2	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
alpha synuclein, partial	1	0	0	1
luciferase	3	0	0	3
histone deacetylase 9 isoform 3	8	0	0	8
Muscarinic acetylcholine receptor M5	0	4	0	5
Alpha-2C adrenergic receptor	0	5	0	5
Glutamate receptor ionotropic, kainate 1	1	0	0	1
Glutamate receptor ionotropic, kainate 2	1	0	0	1
Glutamate receptor ionotropic, kainate 3	1	0	0	1
Fatty-acid amide hydrolase 1	1	1	0	2
Glutamate receptor ionotropic, kainate 4	1	0	0	1
Leukotriene B4 receptor 1	1	2	0	4
Glutamate receptor ionotropic, kainate 5	1	0	0	1
Leukotriene B4 receptor 2	1	1	0	3
Asialoglycoprotein receptor 1	0	1	1	2
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Amino acid transporter	0	1	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
Purine nucleoside phosphorylase	0	2	0	2
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Shiga toxin subunit A	0	1	0	1
Adenylate cyclase type 1	0	1	0	1
Cocaine esterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
Albumin	0	0	3	3
Major prion protein	0	0	1	1
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	2	2
Integrin beta-1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	5	1	6
Muscarinic acetylcholine receptor M3	0	5	1	6
Muscarinic acetylcholine receptor M4	0	6	1	7
5-hydroxytryptamine receptor 1A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	3	0	4
Muscarinic acetylcholine receptor M5	0	5	1	6
Beta-2 adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M2	0	5	1	6
Angiotensin-converting enzyme	0	1	0	1
Integrin alpha-4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
Carbonyl reductase [NADPH] 1	0	0	0	1
Beta-1 adrenergic receptor	0	1	0	1
D	0	2	0	2
D(3) dopamine receptor	0	3	0	3
Alpha-2B adrenergic receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
D(1B) dopamine receptor	0	2	0	3
Adenylate cyclase type 3	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
D(1B) dopamine receptor	0	2	0	2
Beta-3 adrenergic receptor	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
D(4) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
C-8 sterol isomerase	0	1	0	1
Delta-type opioid receptor	0	7	3	11
Mu-type opioid receptor	0	9	3	15
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Kappa-type opioid receptor	0	5	3	9
Alpha-1A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	3	0	3
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
5-hydroxytryptamine receptor 2B	0	1	0	1
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	4	0	4
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	3	0	3
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	2	0	2
Sigma intracellular receptor 2	0	3	0	3
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Protease	0	3	0	3
Adenylyl cyclase 7	0	1	0	1
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Sodium channel protein type 10 subunit alpha	0	2	0	2
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	4	0	7
Prostaglandin G/H synthase 1	0	3	0	3
Caspase-1	0	2	0	3
Caspase-3	0	2	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Caspase-4	0	2	0	2
Caspase-5	0	2	0	2
Caspase-9	0	2	0	2
Acid-sensing ion channel 1	0	1	0	1
Mu-type opioid receptor	0	8	1	9
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Phospholipase A2, major isoenzyme	0	1	0	1
Procathepsin L	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-4	1	4	2	8
Neuronal acetylcholine receptor subunit beta-2	1	4	2	8
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	4	0	4
C-X-C chemokine receptor type 3	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
tyrosine-protein kinase Yes	2	0	0	2
Leukotriene C4 synthase	0	1	0	1
Macrophage-expressed gene 1 protein	0	1	0	1
Leukotriene C4 synthase	0	0	0	1
Prostaglandin E synthase 2	0	1	0	1
Cysteinyl leukotriene receptor 2	0	0	1	1
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Renin	0	1	0	1
inositol monophosphatase 1	2	0	0	2
Cholecystokinin receptor type A	1	0	0	1
Gastrin/cholecystokinin type B receptor	1	0	0	1
ClpP	4	0	0	4
Cytochrome P450 1A2	0	2	0	2
Cytochrome P450 2C11	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	4	1	5
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	2	0	2
Nociceptin receptor	0	2	0	2
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
Solute carrier family 22 member 1	0	1	0	2
Multidrug transporter MdfA	0	3	0	3
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	2	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Thymidylate synthase	0	3	0	3
Tyrosine-protein kinase ABL1	0	1	1	3
Thymidylate synthase	0	4	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	3	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	3	2	5
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	2	0	2
Dihydrofolate reductase	0	3	0	3
Histidine decarboxylase	0	1	2	3
Trifunctional purine biosynthetic protein adenosine-3	0	3	0	3
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	4	0	4
Reduced folate transporter	0	3	0	3
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	3	0	4
Multidrug resistance associated protein	0	1	0	2
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
caspase-3 isoform a preproprotein	0	1	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Cruzipain	0	2	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
phosphoglycerate kinase	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Metabotropic glutamate receptor 6	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Aromatase	0	0	1	1
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
Beta-lactamase TEM	0	4	0	5
Calcium release-activated calcium channel protein 1	0	1	0	1
methionyl-tRNA synthetase, putative	0	1	0	1
Stromelysin-1	0	2	0	2
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Translocator protein	0	1	1	2
Proteinase-activated receptor 1	0	1	1	2
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	3
Mu-type opioid receptor	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	1	1	3
eyes absent homolog 2 isoform a	1	0	0	1
Phospholipase A2, membrane associated	0	0	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
C-C chemokine receptor type 2	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Beta-lactamase	0	1	0	3
Beta-lactamase	0	2	0	4
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	1
Imipenem-hydrolyzing beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
Beta-lactamase VIM-4	0	0	0	1
Cathepsin L2	0	1	0	1
Cathepsin B	0	1	0	1
Pro-cathepsin H	0	1	0	1
Cathepsin S	0	1	0	1
Cathepsin K	0	2	0	2
Cathepsin K	0	1	0	1
Dipeptidyl peptidase 1	0	1	0	1
Cathepsin Z	0	1	0	1
Cathepsin F	0	1	0	1
STE24	0	0	0	1
Mcl-1	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Bifunctional cytochrome P450/NADPH--P450 reductase	0	0	1	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Bombesin receptor subtype-3	0	0	1	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 2	0	0	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Chain A, Pyruvate kinase, M2 isozyme	0	1	0	1
Chain A, Phosphonopyruvate hydrolase	0	1	0	1
Chain A, Phosphoenolpyruvate-protein phosphotransferase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Lysine-specific demethylase 6B	0	1	0	1
Kynurenine 3-monooxygenase	0	1	0	1
Lysine-specific demethylase 4A	0	1	0	1
Lysine-specific demethylase 5A	0	1	0	1
Lysine-specific demethylase 5C	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Peptidyl-prolyl cis-trans isomerase A	0	1	0	1
Methylcytosine dioxygenase TET2	0	1	0	1
Lysine-specific demethylase 7A	0	1	0	1
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	0	1	0	1
Lysine-specific demethylase 5D	0	1	0	1
Lysine-specific demethylase 4C	0	1	0	1
Lysine-specific demethylase 5B	0	1	0	1
Histone lysine demethylase PHF8	0	1	0	1
Lysine-specific demethylase 2A	0	1	0	1
Lysine-specific demethylase 3A	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Serine hydroxymethyltransferase, cytosolic	0	1	1	2
Thymidylate synthase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase IMP-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Endolysin	0	0	1	1
Cannabinoid receptor 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	2	0	2
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Replicase polyprotein 1a	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
Ornithine transcarbamylase, mitochondrial	0	1	0	1
2-dehydropantoate 2-reductase	0	1	0	1
Fe(3+)-Zn(2+) purple acid phosphatase	0	1	0	1
Complement C1s subcomponent	0	1	0	1
Nitric oxide synthase, endothelial	0	1	0	1
Collagenase 3	0	2	0	2
Nitric oxide synthase, inducible	0	1	0	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Acetylcholinesterase	0	1	0	1
Prolyl 4-hydroxylase, beta polypeptide	0	0	0	1
Gastric inhibitory polypeptide receptor	0	1	0	1
Chain A, Bacterial regulatory proteins, tetR family	0	0	1	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
BRCA1	1	0	0	1
P53	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Vif	0	2	0	2
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Myc proto-oncogene protein	0	1	0	2
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Breakpoint cluster region protein	0	1	0	2
Tyrosinase	0	2	0	2
Ornithine decarboxylase	0	1	0	1
Protein kinase C alpha type	0	0	1	1
Estrogen receptor	0	0	1	1
Endothelin receptor type B	1	0	0	1
Endothelin-1 receptor	1	0	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Alpha-glucosidase MAL12	0	1	0	1
Squalene synthase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	0	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	2
Tubulin beta-2B chain	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	2	1	3
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-1	0	0	1	3
Prenyltransferase homolog	0	0	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
large T antigen	0	1	0	1
Butyrophilin subfamily 3 member A1	0	0	2	3
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
H	0	2	0	2
Phosphotransferase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Cytochrome c oxidase subunit 1	0	1	0	1
Calpain-2 catalytic subunit	0	1	0	1
Transporter	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	1	0	1
Free fatty acid receptor 1	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	1	1
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Cytochrome P450 3A5	0	1	1	2
Amine oxidase [flavin-containing] A	0	1	0	1
Catechol O-methyltransferase	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	1	1	2
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Cannabinoid receptor 2	0	0	1	1
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	2	1	3
Glutamate receptor ionotropic, NMDA 1	0	0	1	1
ATP-binding cassette sub-family C member 8	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	1	1
Glutamate receptor ionotropic, NMDA 2B	0	0	1	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	1	1
Thrombin	0	0	1	1
CDGSH iron-sulfur domain-containing protein 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	1	1
Neuraminidase	0	2	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
L-lactate dehydrogenase A chain	0	1	0	1
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Mitogen-activated protein kinase 10	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Signal transducer and activator of transcription 3	0	1	1	2
Hypoxia-inducible factor 1-alpha	0	1	0	1
Thioredoxin glutathione reductase	0	1	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Beta-lactamase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Neutrophil collagenase	0	2	0	2
P2Y purinoceptor 12	0	1	0	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Thymidine phosphorylase	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain B, Odorant-binding Protein	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Chain A, ODORANT-BINDING PROTEIN	0	1	0	1
Secreted chorismate mutase	0	1	0	1
Heat sensitive channel TRPV3	0	0	1	1
Transient receptor potential cation channel subfamily M member 8	0	1	1	2
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
Farnesyl diphosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Periodontitis, Acute Nonsuppurative

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (625)

Protein Targets (1,717)

Periodontitis, Acute Nonsuppurative

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (625)

Drugs Studied (286)

Protein Targets (1,717)