A group of heterocyclic compounds with a core structure containing a benzene ring fused to a diazepine ring.
| Member | Definition | Role |
|---|
| 11-[2-[4-(2-aminoethyl)-1-piperazinyl]-1-oxoethyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one | | 11-[2-[4-(2-aminoethyl)-1-piperazinyl]-1-oxoethyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| 2-ethyl-4-[[(3-methyl-2-benzofuranyl)-oxomethyl]amino]-1H-1,5-benzodiazepine-3-carboxylic acid ethyl ester | | 2-ethyl-4-[[(3-methyl-2-benzofuranyl)-oxomethyl]amino]-1H-1,5-benzodiazepine-3-carboxylic acid ethyl ester |
| 2-methyl-3-phenyl-3H-1,5-benzodiazepin-4-amine | | 2-methyl-3-phenyl-3H-1,5-benzodiazepin-4-amine |
| 2,4-bis(4-methoxyphenyl)-4-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepine | | 2,4-bis(4-methoxyphenyl)-4-methyl-1,2,3,5-tetrahydro-1,5-benzodiazepine |
| 4-(2-hydroxyphenyl)-8,9-dimethyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one | | 4-(2-hydroxyphenyl)-8,9-dimethyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one |
| 4-[(2-chloro-6-fluorophenyl)-oxomethyl]-7-methyl-5-phenyl-3,5-dihydro-1H-1,4-benzodiazepin-2-one | | 4-[(2-chloro-6-fluorophenyl)-oxomethyl]-7-methyl-5-phenyl-3,5-dihydro-1H-1,4-benzodiazepin-2-one |
| 4-methyl-1-piperazinecarbodithioic acid [2-[(2-methyl-3-phenyl-3H-1,5-benzodiazepin-4-yl)amino]-2-oxoethyl] ester | | 4-methyl-1-piperazinecarbodithioic acid [2-[(2-methyl-3-phenyl-3H-1,5-benzodiazepin-4-yl)amino]-2-oxoethyl] ester |
| 4-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one | | 4-Methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one |
| 4,7,8-Trimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one | | 4,7,8-Trimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one |
| 4,8-dimethyl-1-(phenylmethyl)-3H-1,5-benzodiazepin-2-one | | 4,8-dimethyl-1-(phenylmethyl)-3H-1,5-benzodiazepin-2-one |
| 7-acetamidonitrazepam | | 7-Acetamidonitrazepam |
| 7-aminoclonazepam | | 7-Aminoclonazepam |
| 7-aminonitrazepam | | 7-Aminonitrazepam |
| 7-chloro-4-[(2-fluorophenyl)-oxomethyl]-5-phenyl-3,5-dihydro-1H-1,4-benzodiazepin-2-one | | 7-chloro-4-[(2-fluorophenyl)-oxomethyl]-5-phenyl-3,5-dihydro-1H-1,4-benzodiazepin-2-one |
| 7-chloro-5-(4-fluorophenyl)-4-(1-oxopropyl)-3,5-dihydro-1H-1,4-benzodiazepin-2-one | | 7-chloro-5-(4-fluorophenyl)-4-(1-oxopropyl)-3,5-dihydro-1H-1,4-benzodiazepin-2-one |
| 7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one | | 7-chloro-5,10-dihydrothieno[3,4-b][1,5]benzodiazepin-4-one |
| 7-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one | | 7-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one |
| 7,8-dimethyl-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-phenyl-3H-1,5-benzodiazepin-2-one | | 7,8-dimethyl-1-[2-oxo-2-(1-pyrrolidinyl)ethyl]-4-phenyl-3H-1,5-benzodiazepin-2-one |
| afdx 116 | | 11-[2-[2-(diethylaminomethyl)-1-piperidinyl]-1-oxoethyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| afdx 384 | | N-[2-[2-[(dipropylamino)methyl]-1-piperidinyl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide |
| aq-ra 741 | | 11-[2-[4-[4-(diethylamino)butyl]-1-piperidinyl]-1-oxoethyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| aszonalenin | | (2R,3S,11R)-aszonalenin zwitterion |
| auranthine | | Auranthine |
| bms 214662 | A member of the class of benzodiazepines that is 2,3,4,5-tetrahydro-1H-1,4-benzodiazepine substituted by (1H-imidazol-5-yl)methyl, benzyl, (thiophen-2-yl)sulfonyl, and cyano groups at positions 1, 3R, 4 and 7, respectively. It is a potent inhibitor of farnesyltransferase (IC50 = 1.35nM) which was under clinical development for the treatment of solid tumors. | BMS-214662 |
| cfm 2 | | 1-(4-aminophenyl)-7,8-dimethoxy-3,5-dihydro-2,3-benzodiazepin-4-one |
| chlordesmethyldiazepam | | delorazepam |
| chlordiazepoxide | | 7-chloro-4-hydroxy-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-imine |
| clozapine | A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia. | clozapine |
| cm 7116 | | desalkylflurazepam |
| cycloanthranilylproline | | (S)-(+)-2,3-Dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione |
| desmethylolanzapine | | 4'-N-desmethylolanzapine |
| doxefazepam | | Doxefazepam |
| flumezapine | | Flumezapine |
| gsk525762a | | 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide |
| gv 150013x | | GV 150013X |
| gyki 52466 | | GYKI 52466 |
| ketazolam | | ketazolam |
| l 364373 | | R-L3 |
| l 365260 | | L-365260 |
| lorazepam | | Lorazepam |
| metaclazepam | | metaclazepam |
| N-[2-[[11-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepin-8-yl]sulfonylamino]ethyl]carbamic acid tert-butyl ester | | N-[2-[[11-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepin-8-yl]sulfonylamino]ethyl]carbamic acid tert-butyl ester |
| N-[3-(4-chlorophenyl)-2-methyl-3H-1,5-benzodiazepin-4-yl]benzamide | | N-[3-(4-chlorophenyl)-2-methyl-3H-1,5-benzodiazepin-4-yl]benzamide |
| n-desmethylclobazam | | N-Desmethylclobazam |
| olanzapine | A benzodiazepine that is 10H-thieno[2,3-b][1,5]benzodiazepine substituted by a methyl group at position 2 and a 4-methylpiperazin-1-yl group at position 4. | olanzapine |
| pinazepam | | pinazepam |
| prazepam | | Prazepam |
| ro 20-1815 | | 7-Aminoflunitrazepam |
| ro 24-7429 | | 7-chloro-N-methyl-5-(1H-pyrrol-2-yl)-3H-1,4-benzodiazepin-2-amine |
| sch 16134 | | Quazepam |
| telenzepine | | 1-methyl-10-[2-(4-methyl-1-piperazinyl)-1-oxoethyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one |
| temazepam | | Temazepam |
| tetrazepam | | tetrazepam |
| tifluadom | | Tifluadom |