"Benorylate is suitable for the treatment of recent rheumatoid arthritis of a low to moderate activity as well as for long-term treatment." | ( Müller-Fassbender, H; Schattenkirchner, M, 1975) |
"Chrysotherapy is beneficial in the treatment of rheumatoid arthritis, but gold-induced aplastic anemia may be fatal." | ( Parker, WA; Shearer, CA, 1978) |
"The drugs were equally effective in the treatment of rheumatoid arthritis while the incidence of indomethacin side-effects was 1." | ( Hearron, MS; Miyara, A; Moxley, TE; Royer, GL; Shenker, BM, 1975) |
"D-Penicillamine treatment in rheumatoid arthritis resulted in a fall in plasma alfa-1-antitrypsin-IgA complexes which was significantly more pronounced among responders than among non-responders." | ( Jeppsson, JO; Laurell, CB; Wollheim, FA, 1979) |
"Apart from the conventional treatment of the rheumatoid arthritis with steroidal and non-steroidal antirheumatic remedies, physiotherapy and balneotherapy as well as orthopaedic and surgical measures the basis therapy is an important factor." | ( , 1977) |
"The use of penicillamine in the treatment of rheumatoid arthritis and scheroderma is reviewed." | ( Baum, J, 1979) |
"For years the treatment of rheumatoid arthritis has been based on the assumption that the autoimmune processes and bone lesions occuring in rheumatic patients are due to inflammatory and immune reactions." | ( Symoens, J, 1977) |
"The drugs mainly used for basical treatment of rheumatoid arthritis are cytostatics, D-penicillamine, gold salts and chloroquine." | ( Müller, AE; Thiele, HG, 1976) |
"Chloroquine treatment of rheumatoid arthritis in the absence of any other disease which may cause retinopathy implies negligible risks in adult patients under 50 years of age." | ( Elman, A; Gullberg, R; Nilsson, E; Rendahl, I; Wachtmeister, L, 1976) |
"Salicylates form the basis of drug treatment in rheumatoid arthritis." | ( Barraclough, DR; Laby, B; Muirden, KD, 1975) |
"Aspirin is still the preferred treatment for rheumatoid arthritis and should be tried before ibuprofen." | ( Biundo, JJ; Gum, OB; Weiss, TE, 1976) |
"The efficacy of naproxen in treating rheumatoid arthritis patients was evaluated in a double-blind clinical trial using aspirin as the control drug." | ( Bowers, DE; Dyer, HR; Fosdick, WM; Keller, KE; Rosenberg, AL; Sussman, P; Vancil, ME, 1975) |
"The use of multiple drugs in treating rheumatoid arthritis is based on the assumption that their effects are additive." | ( Muirden, KD, 1976) |
"The approach to the treatment of rheumatoid arthritis is currently undergoing fundamental change." | ( Jaffe, IA, 1992) |
"Hydroxychloroquine is used for the treatment of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)." | ( Littlejohn, GO; McCloud, PI; Morand, EF, 1992) |
"Gold salts are still a first choice for treatment of rheumatoid arthritis." | ( Beyner, F; Buss, W; Ott, H; Van Linthoudt, D, 1991) |
"Bucillamine is a useful medication for treatment of rheumatoid arthritis (RA) but some patients develop side effects from it." | ( Amasaki, Y; Atsumi, T; Fujisaku, A; Jodo, S; Kobayashi, H; Mukai, M; Nakabayashi, T; Nakagawa, S; Sagawa, A; Watanabe, I, 1991) |
"A 54-year-old woman under treatment for rheumatoid arthritis was admitted because of aggravation of dyspnea on effort and restrictive pulmonary dysfunction." | ( Ichijima, K; Iwata, T; Kobashi, Y; Kohri, Y; Mino, M; Nambu, Y; Oida, K; Taguchi, Y; Tomii, K; Yunoki, Y, 1991) |
"A 53-year male patient, treated for rheumatoid arthritis with sulphasalazine, developed a total agranulocytosis." | ( Jonson, B; Kanerud, L; Palmblad, J, 1990) |
"MTX is an effective treatment of rheumatoid arthritis." | ( Willkens, RF, 1990) |
"Accordingly, we surveyed 393 AZA-treated rheumatoid arthritis (RA) patients, who were recruited and enrolled through a nationwide call to rheumatologists." | ( Fries, JF; Singh, G; Spitz, P; Williams, CA, 1989) |
"We conclude that during treatment of rheumatoid arthritis with gold, penicillamine or sulphasalazine, SAA concentrations can be high when serum CRP and ESR are suppressed." | ( Bacon, PA; Grindulis, KA; McConkey, B; Robinson, MW; Scott, DL, 1985) |
"The drugs used in the treatment of rheumatoid arthritis are divided into two classes: a "first aid" and a "back up" group." | ( Lanciani, P, 1985) |
"Sulphasalazine is an effective treatment for rheumatoid arthritis but the response in any individual is unpredictable." | ( Amos, RS; Bax, DE; Greaves, MS, 1986) |
"Of a large importance in the treatment of the rheumatoid arthritis and of the osteoarthrosis is the method of clinical tests of non-steroidal antirheumatic drugs and of the so-called disease-activity modifying substances." | ( Pavelka, K; Trnavský, K, 1987) |
"Numerous drugs are available for the treatment of rheumatoid arthritis." | ( Pinals, RS, 1988) |
"The majority of patients were being treated for rheumatoid arthritis." | ( Kay, A, 1986) |
"The possibility is raised that gold treatment of rheumatoid arthritis patients induces or enhances the formation of platelet-specific autoantibodies, and that gold-induced thrombocytopenia is a drug-induced autoimmune disease." | ( Helmerhorst, FM; Pegels, JG; van der Plas-van Dalen, CM; van der Stadt, RJ; von dem Borne, AE, 1986) |
"Searching for new long-term treatments of rheumatoid arthritis (RA) is taking now different turns." | ( Crouzet, J, 1988) |
"The efficacy of gold treatment in rheumatoid arthritis is hampered by toxicity, most prevalent in early phases, and unresponsiveness which can only be assessed after more than 6 months on therapy." | ( Wollheim, FA, 1988) |
"Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia." | ( Immesoete, C; Joos, R; Proot, F; Williame, LM, 1987) |
"The effects were studied of one week of treatment of rheumatoid arthritis patients with suprofen or ibuprofen on Na+ and K+ excretion, creatinine clearance, urinary enzymes that are markers for tubular damage, and urinary prostaglandins such as PGE2 and 6-keto PGF1 alpha (a stable metabolite of prostacyclin)." | ( Angelini, M; Baldini, L; Barenghi, L; Borsa, M; Carrabba, M; Ceriotti, F; Malandrino, S; Tonon, GC, 1987) |
"Both drugs were effective in the treatment of rheumatoid arthritis and were well tolerated." | ( Schorn, D, 1985) |
"MTX appears to be effective in the treatment of active rheumatoid arthritis but requires close monitoring for toxicity." | ( Alarcón, GS; Billingsley, LM; Guttadauria, M; Luggen, ME; Polisson, RP; Samuelson, CO; Weiner, SR; Williams, HJ; Willkens, RF; Yarboro, C, 1985) |
"Both drugs were effective in the treatment of rheumatoid arthritis and resulted in comparable improvement in efficacy variables." | ( Germain, BF; Meisel, AD, 1985) |
"To assess the benefit of further gold treatment of rheumatoid arthritis (RA) patients who had already received more than 6 g of this metal, 24 such patients were included in a double-blind trial." | ( Cats, A; Dijkmans, BA; Hermans, J; Van der Leeden, H, 1986) |
"The use of D-penicillamine in the treatment of rheumatoid arthritis is known to be complicated by the development of various glomerulonephritides." | ( Johnson, K; Rehan, A, 1986) |
"Cytostatic drugs have been used in the treatment of rheumatoid arthritis but are of limited clinical application due to their severe toxic side-effects." | ( Cunliffe, CJ; Foster, SJ; McCormick, ME, 1983) |
"The effect of this drug in the treatment of rheumatoid arthritis (RA) was evaluated." | ( Goldstein, G; Mielants, H; Newdeck, E; Power, D; Spiro, T; Verbruggen, G; Veys, EM, 1984) |
"In untreated rheumatoid arthritis 20% of the patients has a EOG Lp/Dt ratio lower than the lower 5% limit calculated for normal patients." | ( Broekhuyse, RM; Pinckers, A, 1983) |
"A pilot study evaluated once-daily treatment of rheumatoid arthritis with choline magnesium trisalicylate (CMT) in patients diagnosed as having classical or definite rheumatoid arthritis, with morning stiffness as a major complaint." | ( Boyer, JT; Mann, CC, 1984) |
"Penicillamine treatment of rheumatoid arthritis was compared with gold and other remittive agents by reviewing the literature and studying the patients in our penicillamine clinic with respect to their previous responses to chrysotherapy." | ( Atkins, CJ; Offer, RC; Ruedy, J; Stein, HB, 1984) |
"The cytotoxic agents used to treat rheumatoid arthritis, which likely have nonspecific anti-inflammatory actions and have serious long-term side effects, are also briefly reviewed." | ( Anastassiades, TP, 1980) |
"Our experience with azathioprine in the treatment of rheumatoid arthritis covers ten years, during which 91 rheumatoid patients (66 female and 25 male) received this drug, with a median treatment period of 36 months." | ( Boerbooms, AM; Kruijsen, MW; Speerstra, F; van Beusekom, HJ; van de Putte, LB; Vandenbroucke, JP, 1982) |
"The effectiveness of fenclofenac in the treatment of rheumatoid arthritis was compared in a crossover double-blind study of 30 patients with that of indometacin over a period of two weeks." | ( Bachmann, F, 1980) |
"Two studies of its use in treating rheumatoid arthritis are reported here." | ( Camp, AV, 1981) |
"The place of this new drug in the basic treatment of rheumatoid arthritis requires further study by a double blind test with D-penicillamine, and this is at present in progress." | ( Barbieri, P; Ciompi, ML; Colamussi, V; Mazzoni, MR; Pasero, G; Pellegrini, P, 1980) |
"She had been treated for rheumatoid arthritis for more than ten years using steroids." | ( Hosaka, S; Iida, Y; Morishita, A; Oyama, T; Tsuchiya, K; Uwabe, K, 1995) |
"Cyclosporine may be useful in the treatment of rheumatoid arthritis refractory to other immunosuppressive agents, in doses of less than 10 mg/kg/day to minimize its nephrotoxic potential, that is enhanced with prolonged use or concomitant administration of anti-inflammatory drugs." | ( Figueroa, F; Gutiérrez, F; Jacobelli, S; Martínez, ME; Massardo, L; Rivero, S, 1995) |
"Sulfasalazine is an effective treatment for rheumatoid arthritis (RA), producing improvements in disease parameters similar to those seen with penicillamine, hydroxychloroquine or oral or parenteral gold in comparative clinical trials." | ( Faulds, D; Noble, S; Rains, CP, 1995) |
"Despite the progress in the treatment of rheumatoid arthritis (RA), many patients continue to suffer from persistent and painful synovitis." | ( Aguilera, S; Donoso, I; Pizzi, T, 1994) |
"In recent years we have treated 4 rheumatoid arthritis (RA) patients who developed gold-induced enterocolitis, a well-recognized, although rare, complication of chrysotherapy." | ( Abend, Y; Becker, S; Brautbar, C; Cohen, P; Evron, E; Fenakel, G; Geltner, D; Sthoeger, Z, 1995) |
"Oral glucocorticoids are widely used to treat patients with rheumatoid arthritis, but their effect on joint destruction, as assessed radiologically, is uncertain." | ( Kirwan, JR, 1995) |
"D-penicillamine, a drug used to treat rheumatoid arthritis, Wilson's disease, and cystinuria, can cause myasthenia gravis." | ( Adelman, HM; Mahan, CS; Wallach, PM; Winters, PR, 1995) |
"Sulfasalazine is an efficient treatment for rheumatoid arthritis (RA), but its mode of action is not known." | ( Anaya, JM; Bologna, C; Jorgensen, C; Reme, T; Sany, J, 1993) |
"D-penicillamine has been used in the treatment of rheumatoid arthritis for years." | ( Frey, RA; Keller, F; Michel, BA, 1994) |
"Sulphasalazine a drug used for the treatment of rheumatoid arthritis (RA) shows a wide range of biological activities all of which might contribute to the beneficial clinical effect seen during treatment of RA." | ( Björk, J; Smedegård, G, 1995) |
"In the treatment of rheumatoid arthritis an irreplaceable position is held by so-called disease modifying drugs." | ( Trnavský, K, 1995) |
"The role of corticosteroids in treating rheumatoid arthritis is controversial, but recourse to the available evidence of efficacy should guide patient management decisions." | ( Kirwan, JR; Lim, KK, 1996) |
"Use of methotrexate to treat rheumatoid arthritis is associated with pulmonary adverse effects in 3% to 5% of cases." | ( Cortet, B; Delcambre, B; Duquesnoy, B; Flipo, RM; Lafitte, JJ; Roux, N; Tonnel, AB, 1996) |
"We have reviewed the treatment of rheumatoid arthritis (RA) in pertinent selected literature with a focus on methotrexate (MTX)." | ( Kremer, JM, 1996) |
"They are of value in the treatment of rheumatoid arthritis (RA) and other arthritides with inflammatory characteristics and are frequently used to treat osteoarthritis (OA) when simple analgesics fail to provide relief." | ( Moskowitz, RW, 1996) |
"No alternative therapy recommended to treat acute rheumatoid arthritis in lieu of cortisone proved to be effective." | ( Hetenyi, G; Karsh, J, 1997) |
"During the past few years the treatment of rheumatoid arthritis, the most frequent of the rheumatic inflammatory systemic diseases has improved a great deal." | ( Aeschlimann, AG, 1998) |
"That DMARDs are effective in treating rheumatoid arthritis is beyond question-just how effective they are and what combinations of DMARDs will show improved efficacy will provide data for the next annual review." | ( Brooks, P; Conaghan, PG; Li, E, 1998) |
"To optimize treatment for rheumatoid arthritis (RA) and to define indications for D-penicillamine and methotrexate therapies on an individual basis by taking into account the levels of rheumatoid factor (RF) isotopes circulating in blood." | ( Derevianko, LI; Sivordova, LE; Zavodovskiĭ, BV; Zborovskaia, IA; Zborovskiĭ, AB, 1999) |
"Methotrexate is an effective treatment for rheumatoid arthritis and is fairly well tolerated by patients when used appropriately." | ( Wong, BJ, 1993) |
"Since modern treatment of rheumatoid arthritis (RA) is shifting toward aggressive antirheumatic therapy in an early phase of the disease, diagnostic tests with high specificity are desirable." | ( Breedveld, FC; de Jong, BA; Hazes, JM; Schellekens, GA; van den Hoogen, FH; van Venrooij, WJ; Visser, H, 2000) |
"Leflunomide will find its place in the treatment of rheumatoid arthritis." | ( Andresen, PN; Hansen, G; Hørslev-Petersen, K, 2000) |
"In the treatment of rheumatoid arthritis, one therapy that has been identified as having potential benefit, is herbal medicine (phytotherapy)." | ( Little, C; Parsons, T, 2001) |
"This new concept of immunobiological treatment of rheumatoid arthritis has yielded successful results." | ( Dougados, M; Richard-Miceli, C, 2001) |
"To study the mechanism of treatment of rheumatoid arthritis with Tripterygium wilfordii Hook." | ( Guo, W; Ma, L; Tao, X, 2001) |
"Prior to admission, she had been treated for rheumatoid arthritis with methotrexate 7." | ( Beaman, JM; Hackett, LP; Illett, KF; Luxton, G, 2002) |
"The agent has been developed for the treatment of rheumatoid arthritis, but its multiple immunomodulatory properties may in the future be of interest in the treatment of other rheumatic and immunological diseases." | ( Johnsen, V; Kvien, TK; Rødevand, E, 2001) |
"Bucillamine is used mainly in treating rheumatoid arthritis (RA)." | ( Fujii, K; Kishimoto, N, 2002) |
"The use of TNFalpha blockers in the treatment of rheumatoid arthritis and Crohn's disease, with their dramatic immediate effects, comparable with those of the glucocorticoids but without the side effects of the latter, points us in that direction." | ( Neeck, G, 2002) |
"TNFalpha-antibody treatment for rheumatoid arthritis may compromise the host response to molluscum contagiosum, especially if methotrexate is given additionally." | ( Antoni, C; Cursiefen, C; Dechant, C; Grunke, M; Holbach, LM; Jünemann, A, 2002) |
"We sought to determine the effects of treating rheumatoid arthritis with antirheumatic drugs on these abnormal lipid levels." | ( Choi, HK; Kim, DK; Kim, MY; Lee, SK; Lee, WK; Park, YB; Song, J, 2002) |
"It has also been evaluated for the treatment of rheumatoid arthritis, ankylosing spondylitis and acute 'rheumatic' pain." | ( Fleischmann, R; Iqbal, I; Slobodin, G, 2002) |
"A number of clinical trials for the treatment of rheumatoid arthritis(RA) with infliximab indicated that TNF alpha blockade was effective and well tolerated with the excellent results occurring at 3 and 10 mg/kg in combination with methotrexate." | ( Akahoshi, T; Watabe, H, 2002) |
"Comparisons are made with the treatment of rheumatoid arthritis." | ( Fraser, AG, 2003) |
"We report the case of a female patient treated for rheumatoid arthritis, who had gold salt overdose, and in whom acute cholestatic hepatitis occurred three weeks after beginning of therapy." | ( Basset, C; Denis, J; Poupon, J; Vadrot, J; Zafrani, ES, 2003) |
"Due to these new therapeutic concepts treatment of rheumatoid arthritis with corticoids is experiencing a revival." | ( Kaiser, H, 2003) |
"(1) Low-dose methotrexate, as used to treat rheumatoid arthritis and psoriasis, can cause cutaneous and buccal ulceration." | ( , 2003) |
"Methotrexate (MTX), widely used in the treatment of rheumatoid arthritis (RA), inhibits dihydrofolate reductase (DHFR) and folate-dependent enzymes." | ( Hiyama, K; Kohno, N; Kumagai, K; Maeda, H; Oyama, T, 2003) |
"Precise diagnosis and follow up treatment of rheumatoid arthritis (RA) requires objective quantification, which is still lacking." | ( Bögl, K; Graninger, W; Kainberger, F; Peloschek, P; Smolen, JS; Wick, M, 2003) |
"It has potential for the treatment of rheumatoid arthritis." | ( , 2003) |
"Older disease modifying agents for treating rheumatoid arthritis were limited by long-term toxicity." | ( Finesilver, AG, 2003) |
"Chrysotherapy - the treatment of rheumatoid arthritis (RA) patients with monovalent gold drugs possessing anti-inflammatory and other properties - has been used with some success for more than 70 years; however, the metabolites generated from gold drugs have not been identified positively and the mechanisms of action are not known with certainty." | ( Eisler, R, 2003) |
"A number of clinical trials for the treatment of rheumatoid arthritis with infliximab indicated that TNF alpha blockade was effective and well tolerated, with excellent results occurring at 3 and 10 mg/kg in combination with methotrexate." | ( Budzyńska, R; Zakliczyńska, H, 2004) |
"Etanercept is effective in the treatment of rheumatoid arthritis (RA)when used as monotherapy and in combination with methotrexate(MTX)." | ( Genovese, MC; Kremer, JM, 2004) |
"Anakinra is safe and effective in the treatment of rheumatoid arthritis, both as monotherapy and in combination with other disease-modifying antirheumatic drugs." | ( Cohen, SB, 2004) |
"Anti-TNFalpha treatment in rheumatoid arthritis results in a decrease in the serum titres of RF and anti-CCP antibodies in patients showing clinical improvement, suggesting that these measurements may be a useful adjunct in assessing treatment efficacy." | ( Alessandri, C; Bombardieri, M; Cinquini, M; Magrini, L; Papa, N; Tincani, A; Valesini, G, 2004) |
"MTX is widely used for the treatment of rheumatoid arthritis (RA)." | ( Aarden, LA; de Lathouder, S; Dijkmans, BA; Gerards, AH, 2004) |
"Thus we suggest that for PDT treated rheumatoid arthritis, taking the first 20 min after the injection for outside-the-joint excitation employing HMME maybe a good choice." | ( Dou, XM; Huang, NY; Li, JZ; Yu, CQ; Zhao, HY, 2004) |
"Modern treatment of rheumatoid arthritis." | ( Surányi, P, 2005) |
"Leflunomide is a new drug for the treatment of rheumatoid arthritis." | ( Antoine, JC; Camu, W; Coudeyre, E; Gabelle, A; Hillaire-Buys, D, 2005) |
"Bucillamine (BCL), a treatment for rheumatoid arthritis, occasionally causes proteinuria." | ( Hara, S; Hoshino, J; Katori, H; Sawa, N; Suwabe, T; Tagami, T; Takaichi, K; Takemoto, F; Ubara, Y, 2006) |
"Therefore, active treatment of rheumatoid arthritis is indispensable." | ( Tłustochowicz, W, 2006) |
"To determine whether drugs used in the treatment of rheumatoid arthritis (RA) contribute to the increased risk of respiratory infection or influence its outcome." | ( Coulson, E; Coyne, P; Hamilton, J; Heycock, C; Kelly, CA; Saravanan, V, 2007) |
"Biologicals have revolutionised the treatment of rheumatoid arthritis (RA)." | ( Boyce, SH; Gay, RE; Gay, S; Huber, LC; Ink, BS; Künzler, P; Michel, BA, 2008) |
"Early aggressive treatment of rheumatoid arthritis is associated with improved disease control, slower radiological progression and improved functional outcomes." | ( Alcorn, N; Capell, H; Dale, J; Madhok, R, 2007) |
"Gene expression of ML3000 treated and untreated rheumatoid arthritis synovial fibroblasts were measured with Affymetrix gene arrays." | ( Gay, RE; Gay, S; Kurowska-Stolarska, M; Laufer, S; Michel, BA; Neidhart, M; Ospelt, C, 2008) |
"Methotrexate (MTX), widely used in the treatment of rheumatoid arthritis (RA), inhibits dihydrofolate reductase and folate-dependent enzymes." | ( Drozdzik, M; Herczynska, M; Kurzawski, M; Pawlik, A; Safranow, K, 2007) |
"There has been a paradigm shift in the treatment of rheumatoid arthritis in recent years." | ( Aggarwal, A; Haroon, N; Misra, R, 2008) |
"During treatment of rheumatoid arthritis by oral tacrolimus therapy, gastrointestinal symptoms were common, early, and dose-dependent." | ( Akimoto, K; Kawai, S; Kusunoki, Y; Nishio, S; Takagi, K, 2008) |
"This paper reviews recent approaches to treatment of early rheumatoid arthritis (RA) with disease-modifying antirheumatic drugs (DMARDs)." | ( Sizova, L, 2008) |
"FMS inhibitors may be useful in treating rheumatoid arthritis and other chronic inflammatory diseases." | ( Chaikin, MA; Chen, Y; Cheng, D; Crysler, CS; DesJarlais, RL; Donatelli, RR; Hu, H; Huang, H; Hutta, DA; Manthey, CL; Parsons, WH; Player, MR; Rinker, JM; Schubert, C; Yurkow, E; Zhou, Z, 2009) |
"The efficacy of abatacept in the treatment of rheumatoid arthritis (RA) has been shown in several clinical phase II and phase III trials, wherein abatacept was used in monotherapy, either in combination with methotrexate (MTX) after MTX-failure, in combination with MTX after failure of anti-TNF-alpha therapy or in combination with TNF-alpha blockers." | ( Dejaco, C; Duftner, C; Schirmer, M; Wipfler, E, 2009) |
"In severe untreated rheumatoid arthritis (RA), reductions in high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol and total cholesterol have been noted; this is in line with findings in other pathologies/conditions associated with inflammation or infection, such as sepsis, cancer, trauma or the postoperative period." | ( Choy, E; Sattar, N, 2009) |
"Clinical squeal of the treatment of rheumatoid arthritis patients with methotrexate (MTX) according to the Japanese government recommended dose of 8 mg/week was evaluated prospectively." | ( Abe, S; Hashiramoto, A; Komai, K; Koyama, K; Murata, M; Nakagawa, N; Saegusa, Y; Sakai, Y; Shiozawa, K; Shiozawa, S; Tanaka, C; Tanaka, Y; Terashima, Y; Tsumiyama, K; Yamane, T; Yoshihara, R, 2009) |
"(1) First-line disease-modifying treatment for rheumatoid arthritis is based on "slow-acting" antirheumatic agents, generally methotrexate." | ( , 2009) |
"Leflunomide was licensed for the treatment of rheumatoid arthritis in 1998." | ( Alcorn, N; Madhok, R; Saunders, S, 2009) |
"Methotrexate is effective in treating rheumatoid arthritis (RA)." | ( Chen, A; Liu, J; Wang, H; Wu, D; Xiang, H, 2012) |
"Early treatment of rheumatoid arthritis (RA) has been shown to retard the development of joint damage for a period of up to 5 years." | ( Blåfield, H; Hannonen, P; Järvenpää, S; Karjalainen, A; Kautiainen, H; Korpela, M; Laasonen, L; Leirisalo-Repo, M; Möttönen, T; Puolakka, K; Rantalaiho, V, 2010) |
"The use of glucocorticoids in the treatment of rheumatoid arthritis has been widely employed, but, owing to their systemic side-effects and also their susceptibility to the first pass metabolism, their use is being discouraged." | ( Dhanaraju, MD; Elizabeth, S; Gunasekaran, T, 2011) |
"Despite improved medical treatment of rheumatoid arthritis, carpal tunnel compression, caput ulnae syndrome and palmar and dorsal tenosynovitis with potential tendon rupture represent urgent surgical indications." | ( Villiger, PM; Vögelin, E, 2011) |
"The early diagnosis and treatment of rheumatoid arthritis (RA) are important goals for rheumatologists." | ( Haraoui, B; Pope, J, 2011) |
"Current treatments for rheumatoid arthritis (RA) have long-term side effects such that new treatments are needed that can safely help manage the disease." | ( Dang, H; Kaufman, DL; Tian, J; Yong, J, 2011) |
"Rituximab is licensed for the treatment of rheumatoid arthritis in combination with methotrexate and in patients who did not respond or cannot tolerate tumour necrosis factor antagonists." | ( Becerra-Fernandez, E; Leandro, MJ, 2011) |
"The primary goal in the treatment of rheumatoid arthritis (RA) is to maintain good quality of life by preventing joint destruction and avoiding disability." | ( Ichikawa, N; Yamanaka, H, 2012) |
"The efficacy of mizoribine (MZR) in treatment of rheumatoid arthritis (RA) was retrospectively investigated in terms of drug survival, improvement in Disease Activity Score-28 (DAS28)-C-reactive protein (CRP), and blood MZR concentration obtained 3 h after dosing (MZR-C3)." | ( Akimoto, M; Arishima, Y; Eiraku, N; Izumihara, T; Matsuda, T; Ohkura, S; Ohtsubo, H; Sunahara, N; Yoshitama, T, 2012) |
"Methotrexate (MTX) has been used to treat rheumatoid arthritis at low doses and leukemia at high doses; however, this drug can produce severe side effects." | ( Anderson, ME; Gu, LC; Majumdar, S; Malefyt, TR; Siahaan, TJ; Xu, CR; Yakovleva, TV, 2012) |
"Recently, TGP is widely used to treat rheumatoid arthritis in China." | ( Dai, SM; Zhang, W, 2012) |
"Although various drugs for the treatment of rheumatoid arthritis (RA) have been used in clinics, RA is not completely curable to date." | ( Che, X; Fan, H; Liu, K; Meng, Q; Xu, H; Yang, M; Zhang, Z, 2012) |
"While medications used to treat rheumatoid arthritis (RA) may affect survival in RA, few studies take into account the propensity for medication use, which may reflect selection bias in treatment allocation in survival models." | ( Dasgupta, A; Fries, JF; Hubert, H; Ward, MM; Wasko, MC, 2013) |
"This era of early aggressive treatment of rheumatoid arthritis (RA) calls for criteria that allow timely classification of patients at risk of persistent erosive disease." | ( van de Laar, MA; Vonkeman, HE, 2013) |
"Early, intensive treatment of rheumatoid arthritis (RA) with the combination of (initially high dose) prednisolone, methotrexate and sulfasalazine (COBRA therapy) considerably lowers disease activity and suppresses radiological progression, but is infrequently prescribed in daily practice." | ( Boers, M; den Uyl, D; Dijkmans, B; Kerstens, P; Lems, W; Nurmohamed, M; Raterman, H; ter Wee, M; van Dillen, N; van Schaardenburg, D; Voskuyl, A, 2014) |
"In the Treatment of Early Rheumatoid Arthritis (TEAR) trial, 755 participants with early, poor-prognosis RA were randomized to receive MTX monotherapy or combination therapy (MTX plus etanercept or MTX plus sulfasalazine plus hydroxychloroquine)." | ( Bridges, SL; Cofield, SS; Curtis, JR; Mikuls, TR; Moreland, LW; O'Dell, JR; Ranganath, VK, 2013) |
"Various medications are used for the treatment of rheumatoid arthritis (RA)." | ( Masuko, K; Matsui, T; Tohma, S, 2013) |
"Drug-based treatment of rheumatoid arthritis (RA) has evolved markedly over the past 2 decades." | ( Hakala, M; Jämsen, E; Kauppi, MJ; Lehto, MU; Malmivaara, A; Virta, LJ, 2013) |
"Methotrexate (MTX) is the anchor treatment for rheumatoid arthritis (RA) and has been very thoroughly studied in many different patient populations, as monotherapy and in combination with various other disease modifying antirheumatic drugs and biologic agents, as they became available." | ( Bata, Y; Yazici, Y, 2013) |
"Prednisone is a well-established treatment option in rheumatoid arthritis." | ( Henness, S; Yang, LP, 2013) |
"Tofacitinib was effective in the treatment of active rheumatoid arthritis in patients with an inadequate response or intolerance to at least one DMARDs." | ( Berhan, A, 2013) |
"To improve treatment for rheumatoid arthritis (RA), rheumatologists have embraced patient-reported outcomes; however, limited data are available on patient perceptions of treatment." | ( Nash, P; Nicholls, D, 2013) |
"To compare the approved treatment of rheumatoid arthritis using rituximab + methotrexate (RTX + MTX) versus the off-label treatment variants of RTX in monotherapy or RTX in combination with leflunomide (RTX + LEF)." | ( Bussmann, A; Herzer, P; Listing, J; Richter, A; Strangfeld, A; Wilden, E; Zink, A, 2014) |
"Use of tocilizumab for treating rheumatoid arthritis can become affordable, if costs of its use become lower." | ( Janković, SM; Jovanović, S; Kostić, M; Milenković, MP; Tomović, M, 2014) |
"Our study showed that treatment of early rheumatoid arthritis with a combination regime of traditional DMARDs is highly effective in controlling disease activity as well as cardiovascular risk." | ( Biswas, M; Chatterjee, S; Ghosh, A; Ghosh, S; Sarkate, P, 2013) |
"Rituximab (RTX) treatment in rheumatoid arthritis (RA) patients severely hampers humoral response after influenza vaccination as determined by haemagglutination inhibition assay (HI)." | ( Bijl, M; de Haan, A; Horst, G; Land, J; van Assen, S; Westra, J; Wilting, KR, 2014) |
"Hand exercises are often part of the treatment of hand rheumatoid arthritis; however, it is still unclear whether and what type of exercises is effective in the treatment of this condition." | ( Bergstra, SA; Caljouw, SR; Murgia, A; Te Velde, AF, 2014) |
"Early diagnosis and treatment of rheumatoid arthritis are associated with improved outcomes but current diagnostic tools such as rheumatoid factor or anti-citrullinated protein antibodies have shown limited sensitivity." | ( Dakna, M; Husi, H; Johnsson, H; Klein, J; McInnes, IB; Mischak, H; Mullen, W; Porter, D; Stalmach, A, 2014) |
"Clinical efficacy in the treatment of rheumatoid arthritis with anti-CD20 (Rituximab)-mediated B-cell depletion has garnered interest in the mechanisms by which B cells contribute to autoimmunity." | ( Cao, Y; Finnegan, A; Hamel, KM; Olalekan, SA, 2015) |
"Optimal outcome of treatment in rheumatoid arthritis (RA) is early clinical remission to delay joint damage." | ( Suwannalai, P; Wacharapornin, P, 2014) |
"Current treatment of rheumatoid arthritis includes systemic administration of glucocorticoids." | ( Boerman, OC; Gerrits, D; Laverman, P; Metselaar, JM; Storm, G; van der Geest, T; van Lent, PL, 2015) |
"Antimalarials have been used for the treatment of rheumatoid arthritis (RA) for several decades." | ( Cusnir, I; Dobing, S; Jones, N; Russell, A, 2015) |
"TAC was approved in Japan for the treatment of rheumatoid arthritis (RA) in 2005." | ( Ishida, K; Shiraki, K; Yoshiyasu, T, 2015) |
"After clinical remission of scabies, treatment of active rheumatoid arthritis with adalimumab was restarted without any complications." | ( Čulo, MI; Gudelj Gračanin, A; Marković, I; Mitrović, J; Morović-Vergles, J; Pukšić, S, 2015) |
"Methotrexate is the first line of treatment of rheumatoid arthritis." | ( Almeida, CR; Bernardes, GJ; Bismuth, G; Burnet, M; Carmo, AM; Cavaco-Paulo, A; Charvet, C; Freitas, J; Gomes, AC; Lager, F; Le Roux, D; Loureiro, A; Machacek, C; Moreira, A; Nogueira, E; Nogueira, P; Ohradanova-Repic, A; Preto, A; Renault, G; Stockinger, H, 2015) |
"Methotrexate is in the centre of the treatment of rheumatoid arthritis." | ( Fiehn, C, 2016) |
"Sulfasalazine (SSZ), a drug used in the treatment of rheumatoid arthritis (RA), inhibits glutamate-cystine transport, and suppressed CD44v-dependent tumor growth and increased sensitivity to cytotoxic drugs in an in vivo study." | ( Kubo, T; Morikawa, A; Morita, T; Nagano, O; Saya, H; Takayama, T, 2016) |
"Recent advance in treatment of rheumatoid arthritis (RA) has been derived by biological disease-modifying antirheumatic drugs (bDMARDs) targeting cytokines." | ( Sonomoto, K; Tanaka, Y, 2015) |
"The early diagnosis and treatment of rheumatoid arthritis (RA) is important to reduce joint destruction." | ( Funayama, T; Hara, I; Onishi, S; Ozeki, E; Sakane, M; Tsukanishi, T; Yamazaki, M, 2016) |
"Developing inhibitors of any kinase to treat of rheumatoid arthritis has proved problematic with regard to both efficacy and selectivity." | ( Norman, P, 2016) |
"A 75-year-old female with untreated rheumatoid arthritis presented with two weeks of behavioral changes and cognitive decline." | ( Killory, BD; Nouh, AM; Ollenschleger, MD; Song, X; Stretz, C, 2016) |
"The biologics have revolutionized the treatment of rheumatoid arthritis (RA)." | ( Yamaoka, K, 2016) |
"Proper diagnosis and treatment of rheumatoid arthritis are extremely important to optimize treatment outcomes." | ( Al Faruque, H; Chang, Y; Hong, J; Kang, YM; Kim, EH; Lee, J; Lee, JJ; Park, JW; Sung, S, 2016) |
"Biologics have revolutionized the treatment of rheumatoid arthritis (RA)." | ( Yamaoka, K, 2016) |
"To evaluate subcutaneous SBI-087 to treat rheumatoid arthritis (RA)." | ( Aelion, J; Bhattacharya, I; Damjanov, N; Diehl, A; Gourley, I; Greenwald, M; Menon, S; Peeva, E; Tlustochowicz, M, 2016) |
"They used it successfully in treating rheumatoid arthritis (RA)." | ( Malaviya, AN, 2016) |
"Since prednisolone is used to treat rheumatoid arthritis at a dose ≤10 mg/d, the patients were divided based on the prednisolone dose into the groups treated at >10 and ≤10 mg/d, and the onset time was investigated in each group." | ( Hara, A; Kizu, J; Matsumoto, K; Yokoyama, Y, 2017) |
"It is established that treatment for rheumatoid arthritis can exacerbate latent viral issues, but this has not specifically been reported for vestibular neuritis." | ( Roberts, RA, 2018) |
"Corticosteroids (CSs), used to treat rheumatoid arthritis (RA), confer a risk of adverse events (AEs)." | ( Kishimoto, M; Ohde, S; Okada, M; Suda, M; Tsuda, T, 2018) |
"Optimal targeted treatment in rheumatoid arthritis requires early identification of failure to respond." | ( Chapman, D; DeMasi, R; Fallon, L; Keystone, E; Lee, EB; van Vollenhoven, RF; Wilkinson, B; Zwillich, SH, 2019) |
"While highly efficacious in treating rheumatoid arthritis (RA), the approved Janus kinase (JAK) inhibitor, Tofacitinib (Tofa, CP-690 550), has dose-dependent toxicities that limit its clinical application." | ( Galdamez, J; Goldring, SR; Lele, SM; Liu, Y; Mikuls, TR; Purdue, PE; Soni, DM; Wang, D; Wang, X; Wei, X; Wu, J; Zhao, G, 2018) |
"Medication-based strategies to treat rheumatoid arthritis are crucial in terms of outcome." | ( Alten, R; Baerwald, C; Behrens, F; Braun, J; Burkhardt, H; Burmester, G; Detert, J; Fiehn, C; Frerix, M; Gaubitz, M; Gause, A; Gromnica-Ihle, E; Holle, J; Iking-Konert, C; Kellner, H; Krause, A; Krüger, K; Kuipers, J; Leipe, J; Lorenz, HM; Müller-Ladner, U; Nothacker, M; Nüsslein, H; Rubbert-Roth, A; Schneider, M; Schulze-Koops, H; Seitz, S; Sitter, H; Specker, C; Tony, HP; Wassenberg, S; Weseloh, C; Wollenhaupt, J, 2018) |
"Methotrexate has been used in treatment of rheumatoid arthritis (RA) since the 1980s and to this day is often the first line medication for RA treatment." | ( Cronstein, B; Friedman, B, 2019) |
"The use of methotrexate (MTX) to treat rheumatoid arthritis (RA) is increasing." | ( Kikuchi, N; Koda, M; Kono, M; Murakami, K; Shimizu, T; Tanaka, H; Uesugi, M; Yamazaki, M, 2018) |
"Current guidelines on the treatment of rheumatoid arthritis (RA) recommend early therapy targeting the achievement of low disease activity (LDA) or clinical remission." | ( Abud-Mendoza, C; Borlenghi, CE; De Angelo Andrade, M; Mendez-Patarroyo, P; Pedersen, R; Vlahos, B; Zerbini, CAF, 2018) |
"She had also been treated for rheumatoid arthritis with prednisolone, methotrexate, and tocilizumab (interleukin-6 receptor inhibitor)." | ( Fujii, Y; Goto, Y; Imura, H; Matono, T; Nagano, S; Tobino, K; Yaguchi, T; Yamate, R, 2019) |
"Clinical remission is the treatment target in rheumatoid arthritis (RA)." | ( Cai, YM; Gan, YZ; He, J; Li, J; Li, R; Li, SG; Li, ZG; Liao, H; Liu, JJ; Liu, X; Shi, LJ; Sun, XL; Xu, J; Ye, H; Zhang, RJ; Zhao, JX, 2019) |
"We enrolled six treatment-naive rheumatoid arthritis (RA) patients whose blood samples were collected for phenotypic and molecular studies along with 12-week iguratimod monotherapy." | ( Bao, C; Du, F; Fu, Q; Guo, Q; Hao, P; Liu, M; Liu, Y; Tang, L; Yan, Q; Ye, Y; Zhang, X, 2019) |
"Oral treatment of rheumatoid arthritis (RA) with the immunomodulator, leflunomide (LEF), is associated with systemic side effects namely immunosuppression and hepatotoxicity." | ( Boraie, N; Helmy, MW; Nafee, N; Zewail, M, 2019) |
"Patients with long-term, treated, rheumatoid arthritis (RA) show abnormalities in their circulating CD4+ T-lymphocytes, but whether this occurs in recently diagnosed naïve patients to disease-modifying drugs (DMARDs) is under discussion." | ( Albarrán, F; Álvarez-Mon, M; Bohórquez, C; Chara, L; Díaz, D; Gómez Lahoz, AM; Monserrat, J; Movasat, A; Pérez, A; Ruíz, L; Sánchez, AI; Sanz, I, 2019) |
"We describe the Treatment for Rheumatoid Arthritis and Interstitial Lung Disease 1 (TRAIL1) trial, a multicenter randomized, double-blind, placebo-controlled, phase 2 study of the safety, tolerability and efficacy of pirfenidone in patients with RA-ILD." | ( Chambers, DC; Danoff, SK; Dellaripa, PF; DiFranco, D; Goldberg, HJ; Haynes-Harp, S; Hurwitz, S; Kolb, M; Peters, EB; Rosas, IO; Solomon, JJ; Spino, C; Woodhead, F, 2019) |
"A total of 170 patients who had been treated for rheumatoid arthritis at our hospital from August 2016 and June 2018, were enrolled as research objects." | ( Ji, H; Sun, Q; Tang, Z, 2019) |
"Clinical trials of treating rheumatoid arthritis with Tripterygium Glycosides Tablets published by Meta-analysis were retrieved from EMbase,PubMed,Clinical Trials,Web of Science,Cochrane Library,CNKI,Wanfang,VIP,CBM and Chi CTR,and comprehensively analyzed." | ( Gao, Y; Han, XC; Wang, HL; Wang, HZ; Yang, YZ; Zhu, GZ, 2019) |
"Despite significant progress in treatment of rheumatoid arthritis (RA), a considerable part of patients remains resistant to the current therapy, apparently for the reasons of undefined mechanisms of its pathogenesis." | ( Khomenko, V; Stanislavchuk, M; Zaichko, K; Zaichko, N, 2020) |
"RESULTS Treatment of rheumatoid arthritis with RT-Pt(II) significantly reduced the levels of IL‑1ß, IL-6, IL-8, MMP-1, and MMP-13 in synovial fluid of mice in a dose-dependent manner." | ( Cao, L; Cui, L; Cui, Z; Lin, Y; Liu, Y, 2020) |
"Glucocorticoids (GCs) show powerful treatment effect on rheumatoid arthritis (RA)." | ( Cai, L; Chen, X; Feng, Y; Li, C; Li, H; Mei, Z; Wang, Y; Yan, F; Zhong, Z, 2020) |
"Up to 3% of methotrexate (MTX)-treated rheumatoid arthritis (RA) patients might develop liver fibrosis or cirrhosis, requiring effective screening algorithms." | ( Ayonrinde, OT; Keen, HI; Olsson-White, DA; Olynyk, JK; Paramalingam, S, 2022) |
"To identify the optimal treatment for rheumatoid arthritis (RA) after the regression of lymphoproliferative disorders (LPDs)." | ( Fujii, T; Harigai, M; Kaneko, Y; Kuramoto, N; Nakano, K; Saito, K; Saito, R; Saito, S; Sasaki, S; Sugimoto, N; Suzuki, Y; Takada, H; Tanaka, M; Tanaka, Y, 2022) |
"Even though new drugs for the treatment of rheumatoid arthritis (RA) have been developed, methotrexate (MTX) remains a commonly used drug for RA management." | ( Abdulah, R; Destiani, DP; Dewi, S; Naja, S; Rahmadi, AR; Sulaiman, SAS, 2021) |
"Patients aged 18 years and older with treatment naive rheumatoid arthritis, symptom duration less than 24 months, moderate to severe disease activity, and rheumatoid factor or anti-citrullinated protein antibody positivity, or increased C reactive protein." | ( Baecklund, E; Bakland, G; Brodin, E; Cagnotto, G; Ellingsen, T; Faustini, F; Grondal, G; Grøn, KL; Gudbjornsson, B; Haavardsholm, EA; Heiberg, MS; Hendricks, O; Hetland, ML; Hultgård Ekwall, AK; Husmark, T; Hyldstrup, LH; Hørslev-Petersen, K; Just, SA; Kapetanovic, M; Krabbe, S; Lampa, J; Larsson, P; Laurberg, TB; Lend, K; Lindqvist, J; Ljoså, MA; Lorenzen, T; Nordström, D; Nurmohamed, M; Olsen, IC; Olsson, ÅR; Rizk, M; Rudin, A; Söderbergh, A; Sokka-Isler, T; Stevens, DJ; Tuompo, R; Twisk, J; Uhlig, T; Uhrenholt, L; van Vollenhoven, R; Vedder, D; Østergaard, M, 2020) |
"Cortisone was introduced in the treatment of rheumatoid arthritis (RA) in 1948 by Hench and colleagues at the Mayo Clinic which resulted in dramatic improvement of inflammation, function and sense of well-being." | ( Conn, DL, 2021) |
"Tocilizumab is widely used in treating rheumatoid arthritis and has the potential to reduce the mortality rate among severe COVID-19 patients." | ( Huang, KY; Kuo, MH; Lai, NS; Lee, CH; Lu, MC; Tseng, CW; Tseng, KC; Tung, CH, 2021) |
"Methotrexate, which had been used to treat her rheumatoid arthritis, could subsequently be administered in a reduced dose." | ( Horimoto, Y; Murakami, F; Saito, M; Shimizu, H; Tada, K; Tamura, N; Yamaji, K, 2021) |
"In the treatment of rheumatoid arthritis (RA), Janus kinase inhibitors (jakinibs) represent an emerging class of targeted therapies in addition to biologics." | ( Kavanaugh, A; McInnes, IB; Tanaka, Y; Wicklund, J, 2022) |
"Thus, MTX-PEC demonstrated potential to treat rheumatoid arthritis, with the possibility of decreasing the systemic exposure to the drug." | ( Agostini, SBN; Bassi da Silva, J; Bruschi, ML; Carvalho, FC; de Oliveira, MK; Dos Santos, RS; Elisei, LS; Freitas, JTJ; Galdino, G; Giusto, LADR; Lino, MES; Malta, IHS; Moraes, TR; Nogueira, DA; Novaes, RD; Pereira, GR; Rodrigues, RF; Santos, AMD, 2021) |
"Tofacitinib tablet is approved for the treatment of rheumatoid arthritis (RA)." | ( Li, Y; Sun, Y; Wei, S; Zhang, L; Zong, S, 2021) |
"One of the treatments for rheumatoid arthritis (RA) was methotrexate which a disease modifying antirheumatic drug therapy." | ( Achmad, A; Putra Suryana, BP; Rahmayanti, TY, 2021) |
"Sinomenine (SIN) is a clinical drug for treating rheumatoid arthritis (RA) in China." | ( Dong, Y; Du, Q; Ke, J; Lai, H; Liu, J; Liu, L; Lv, Y; Peng, C; Wang, P; Yi, L; Zhi, Y; Zhou, H, 2021) |
"Methotrexate (MTX) is the first line treatment of rheumatoid arthritis (RA), and methylation changes in bulk T cells have been reported after treatment with MTX." | ( Andreassen, BK; Evenrød, IM; Flåm, ST; Franke, A; Franzenburg, S; Gervin, K; Guderud, K; Lie, BA; Mjaavatten, MD; Mæhlen, MT; Norli, ES; Rayner, S; Sunde, LH, 2021) |
"a current standards-of-care for treating flares in rheumatoid arthritis patients)." | ( Bijlsma, JWJ; Bos, R; Kothekar, M; Lammers, T; Metselaar, JM; Middelink, LM; Raut, A; van Laar, JM; Vonkeman, HE; Westhovens, R; Wortel, CH; Yao, SL, 2022) |
"Abatacept (CTLA4-Ig) is used for the treatment of Rheumatoid arthritis." | ( Kadu, P; Kale, P; Kulkarni, D; Naik, J; Pandya, A, 2022) |
"Methotrexate (MTX) is the first-line treatment for rheumatoid arthritis (RA)." | ( Cao, Z; Huang, Q; Li, C; Liu, R; Liu, Y; Lu, A; Lu, C; Song, Y; Xue, Z; Yu, L; Zhang, Z; Zhu, D, 2022) |
"Current treatment for Rheumatoid arthritis (RA) utilizes Disease-modifying antirheumatic drugs, non-steroidal anti-inflammatory drugs or its combination, to decrease joint inflammation." | ( Babasahib, SK; Born, RW; Raghavendra, NM, 2022) |
"Hydroxychloroquine, when used to treat patients with rheumatoid arthritis or systemic lupus erythematosus, has been found to reduce cardiovascular disease (CVD)." | ( Porter, M; Weidman-Evans, E, 2022) |
"Rituximab is used for the treatment of active rheumatoid arthritis." | ( Avgoustidis, N; Bertsias, A; Bertsias, G; Flouri, I; Kalogiannaki, E; Kougkas, N; Papalopoulos, I; Repa, A; Sidiropoulos, P, 2022) |
"Whereas in the treatment of rheumatoid arthritis much evidence exists on the effects of current pharmacologic treatment on clinical outcomes, little is known about the effects on patient-reported outcomes." | ( de Jong, PHP; Hazes, JMW; Kok, MR; Kuijper, TM; Lopes-Barreto, D; Luurssen-Masurel, N; van den Dikkenberg, M; Weel-Koenders, AEAM, 2023) |
"It is widely used for the treatment of rheumatoid arthritis in clinic." | ( Dai, Y; Huang, D; Lin, L; Lin, W; Shao, S; Wang, Y; Xia, Y, 2022) |
"Sulfasalazine has been widely used in treatment of rheumatoid arthritis and spondyloarthritis." | ( David, R; Jayachandran, M; Koshy, V; Marwaha, V; Mithun, CB; Nair, AS; Padmanabhan, DS; Palatty, PL; Santhakumari, V; Singh, SK; Singhal, A; Suman, SK; Surendran, S; Tiwari, A; Yadav, P, 2022) |
"New evidence for the treatment of rheumatoid arthritis (RA) has emerged during the last year." | ( Adinolfi, A; Bortoluzzi, A; Filippou, G; Garaffoni, C; Giollo, A; Sakellariou, G; Scirè, CA; Silvagni, E; Sirotti, S; Ughi, N, 2022) |
"Methotrexate, the cornerstone treatment of rheumatoid arthritis, initiated at the pre-arthritis stage of symptoms and subclinical inflammation, did not prevent the development of clinical arthritis, but modified the disease course as shown by sustained improvement in MRI-detected inflammation, related symptoms, and impairments compared with placebo." | ( Allaart, CF; Boer, AC; Böhringer, S; Burgers, LE; Dakkak, YJ; de Jong, PHP; de Witt-Luth, ME; Huizinga, TWJ; Kok, MR; Krijbolder, DI; Molenaar, ETH; Niemantsverdriet, E; Park, YJ; van der Helm-van Mil, AHM; van Dijk, BT; Verstappen, M; Visser, K, 2022) |
"Gold salts have been used to treat rheumatoid arthritis (RA) since the 1940s, and, with advances in nanotechnology, the use of nanogold provides multiple options for anti-inflammatory therapies." | ( Carrasco-Hernández, AR; Castellanos-Ponce, I; Duarte-Moller, JA; Esparza-Ponce, HE; Espino-Solís, GP; González-Chávez, SA; López-Loeza, SM; Neri-Flores, MÁ; Pacheco-Tena, C; Ruvalcaba-Ontiveros, RI; Vázquez-Olvera, G, 2022) |
"Filgotinib has been approved for the treatment of rheumatoid arthritis (RA) in adults who respond inadequately to disease-modifying antirheumatic drugs (DMARDs) in Europe and Japan." | ( Chu, T; Liu, B; Liu, Z; Lu, L; Ma, D; Pan, L; Ren, J; Wang, Y; Yu, L, 2022) |
"The most used drug for the treatment of rheumatoid arthritis (RA) remains methotrexate (MTX)." | ( Chang, JS; Chang, MJ; Cheng, T; Li, XF; Liu, GY; Qiao, J; Song, S; Zhang, JQ; Zhang, SX; Zhao, R, 2023) |
"Leflunomide is a commonly used treatment for rheumatoid arthritis." | ( Aicha, BT; Hana, S; Ines, M; Issam, S; Kawther, BA; Leila, A; Leila, M; Lobna, BA; Mouna, BS; Olfa, S; Rawdha, T; Selma, B; Takoua, BB, 2023) |
"bulbifera in the treatment of rheumatoid arthritis, which laid a theoretical and experimental foundation for further development and application of the medicinal plant." | ( Chen, SY; Chen, Y; Gong, ZP; Huang, Y; Lan, YY; Li, YT; Tang, J; Wang, YL; Wu, D; Zhang, Q; Zheng, L, 2022) |
"With the in-depth research on treatment drugs of rheumatoid arthritis (RA), a variety of disease modifying anti-rheumatic drugs (DMARDs) have been approved for the treatment of RA." | ( Dai, LY; Zhao, JX, 2022) |
"Baricitinib (BARI) is approved for the treatment of rheumatoid arthritis (RA) after failure of conventional synthetic and biologic disease modifying anti-rheumatic drugs (cs/bDMARDs) in combination with methotrexate (MTX) or as monotherapy." | ( Bayat, S; Bohr, D; Hartmann, F; Kleyer, A; Knitza, J; Krönke, G; Schett, G; Simon, D; Tascilar, K, 2022) |
"Baricitinib (BARI) is approved for the treatment of rheumatoid arthritis (RA) after failure of conventional synthetic and biologic disease modifying anti-rheumatic drugs (cs/bDMARDs) in combination with methotrexate (MTX) or as monotherapy." | ( Bayat, S; Bohr, D; Hartmann, F; Kleyer, A; Knitza, J; Krönke, G; Schett, G; Simon, D; Tascilar, K, 2022) |
"Baricitinib (BARI) is approved for the treatment of rheumatoid arthritis (RA) after failure of conventional synthetic and biologic disease modifying anti-rheumatic drugs (cs/bDMARDs) in combination with methotrexate (MTX) or as monotherapy." | ( Bayat, S; Bohr, D; Hartmann, F; Kleyer, A; Knitza, J; Krönke, G; Schett, G; Simon, D; Tascilar, K, 2022) |
"Methotrexate (MTX) is a first-line treatment for rheumatoid arthritis (RA), but its clinical use is greatly limited by the adverse effects and poor patient compliance caused by traditional oral administration or injection." | ( Ma, Z; Tao, X; Wang, Q; Yang, J; Zhao, W; Zheng, L, 2023) |
"Glucocorticoids are used in the treatment of rheumatoid arthritis since many decades." | ( van der Goes, MC, 2022) |
"Recently, transdermal treatment of rheumatoid arthritis (RA) has received increasing attention due to the advantages of improving patient compliance and avoiding gastrointestinal side effects." | ( Li, Y; Ma, T; Wang, Q; Yang, J; Zhang, Y; Zhao, W; Zheng, L, 2023) |
"Abatacept (Orencia) is a drug used to treat patients with rheumatoid arthritis." | ( Mohamed Ahamada, M; Wu, X, 2023) |
"To compare the features of difficult-to-treat rheumatoid arthritis (D2TRA) patients using two different definitions according to the previous failure of targeted therapies." | ( Allanore, Y; Avouac, J; Combier, A; Hecquet, S; Miceli-Richard, C; Molto, A; Pons, M; Steelandt, A; Wendling, D, 2023) |
"They are widely used in China to treat rheumatoid arthritis (RA), but proof of their use as an evidence-based medicine is little." | ( Fang, J; Hu, J; Huang, Z; Li, W; Liu, C; Liu, M; Lv, L; Ma, Y; Wang, H; Wang, Y; Zheng, X; Zhu, H; Zhu, Z, 2023) |
"As significant advances in the field of treatment for rheumatoid arthritis (RA), there is a great need to identify the healthcare outcomes such as treatment satisfaction and health-related quality of life (HRQoL) of patients with various treatment options." | ( Choe, JY; Jeon, JY; Kim, SK; Lee, SH; Sun, J; Yoo, HJ, 2023) |
"However, its potential mechanism in the treatment of rheumatoid arthritis (RA) remains unknown." | ( Bao, TR; Gao, XX; He, XL; Jia, JM; Sun, XD; Wang, AH; Wang, Y; Yan, H; Yang, YC; Zhao, L; Zhu, SY, 2023) |
"A 56-year-old woman was treated for rheumatoid arthritis for 17 years with methotrexate (MTX)." | ( Kato, H; Kohsaka, H; Misumi, K; Suzuki, M, 2023) |
"The optimal first-line treatment in early rheumatoid arthritis (RA) is debated." | ( Aga, AB; Back, J; Bakland, G; Bay Laurbjerg, T; Brodin, E; Bøyesen, P; Faustini, F; Giovanni, C; Gjertsson, I; Glinatsi, D; Grenholm, E; Grondal, G; Gudbjornsson, B; Haavardsholm, EA; Heiberg, MS; Hendricks, O; Hetland, ML; Hørslev-Petersen, K; Just, SA; Kapetanovic, MC; Kastbom, A; Krabbe, S; Lampa, J; Larsson, P; Lend, K; Lindegaard, H; Lindqvist, J; Ljoså, MK; Lorenzen, T; Nordström, DC; Nurmohamed, MT; Olsen, IC; Parmanne, P; Rannio, T; Rizk, M; Rudin, A; Söderbergh, A; Sokka, T; Stevens, DJ; Uhlig, T; Uhrenholt, L; van Vollenhoven, RF; Vedder, D; Ørnbjerg, LM; Østergaard, M, 2023) |
"In the clinical treatment of rheumatoid arthritis, we should focus on improving the blood lipid indexes such as TC and HDL-C, and explore more targeted individualized administration, so as to achieve better and faster treatment effect in patients with rheumatoid arthritis." | ( Chen, K; Huang, X; Wang, Y; Xie, H; Yao, G; Zhu, Y, 2023) |
"Methotrexate is used in treatment of rheumatoid arthritis." | ( Jingzhou, Z; Xin, KQ; Xiong, Z, 2023) |