Paraphilias

Disorders that include recurrent, intense sexually arousing fantasies, sexual urges, or behaviors generally involving nonhuman objects, suffering of oneself or partners, or children or other nonconsenting partners. (from DSM-V)

Synonym
Sex Deviations
Paraphilic Disorders
Paraphilias

Excerpt	Reference
"Paraphilic disorders are Axis I psychiatric afflictions."	( Berlin, FS, 1989)
"Paraphilias are psychiatric disorders characterized by deviant and culturally non-sanctioned sexual fantasies, thoughts, and/or behaviors."	( Berlin, FS; Saleh, FM, 2003)
"Paraphilic disorders are psychiatric syndromes primarily characterized by deviant sexual thoughts, cravings, urges, and/or behaviors."	( Berlin, FS; Saleh, FM, 2003)
"Hypersexuality and paraphilias are complications not uncommonly found in patients with PD under dopaminergic treatment."	( Becker, N; Fabiani, G; Munhoz, RP; Teive, HAG, 2009)

Excerpt	Reference
"A patient with multiple paraphilias who had been treated for several years with sex drive reducing agents (cyproterone acetate and medroxyprogesterone acetate) with little effect on sexual activity or fantasy was offered treatment with long-acting leuprolide acetate, on LHRH agonist."	( Dickey, R, 1992)
"We report two cases in which paraphilias responded to treatment with clomipramine."	( Kim, KY; Leo, RJ, 1995)
"Twenty-four men with paraphilias (PA; n = 13) and paraphilia-related disorders (PRD; n = 11) were consecutively treated with sertraline (mean dose, 100 mg/day; mean duration, 17."	( Kafka, MP, 1994)
"Treatment of the paraphilic disorders using behavioral, cognitive, pharmacological, and social interventions has been shown to have limited success with poorly motivated or noncompliant patients."	( Bradford, JM; Curry, S; Greenberg, DM; O'Rourke, A, 1996)
"Hypersexuality and paraphilias are complications not uncommonly found in patients with PD under dopaminergic treatment."	( Becker, N; Fabiani, G; Munhoz, RP; Teive, HAG, 2009)
"The treatment of paraphilias remains a challenge in the mental health field."	( Assumpção, AA; Bradford, JM; Garcia, FD; Garcia, HD; Thibaut, F, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	282 (64.38)	23.3326
1990's	62 (14.16)	12.5806
2000's	58 (13.24)	18.1394
2010's	27 (6.16)	28.8240
2020's	9 (2.05)	9.53

Drug	Relationship Strength	Studies	Trials
ammonium hydroxide	low	2	0
choline	low	1	0
salicylic acid	low	1	0
nitrites	low	1	0
nitrous oxide	low	2	0
toluene	low	1	0
urea	low	1	0
3,4-methylenedioxyamphetamine	low	27	0
alprazolam	low	1	0
amitriptyline	low	1	0
amobarbital	low	2	0
benserazide	low	1	0
bupivacaine	low	1	0
buspirone	low	3	0
carbamazepine	low	1	0
chlordiazepoxide	low	1	0
chlorpromazine	medium	4	2
cimetidine	low	1	0
citalopram	low	1	0
clomipramine	medium	4	1
clonazepam	low	1	0
desipramine	medium	2	1
amphetamine	low	2	0
valproic acid	medium	1	1
droperidol	low	1	0
fenfluramine	low	1	0
fluphenazine	low	3	0
fluoxetine	medium	15	2
flutamide	low	1	0
haloperidol	low	3	0
phenelzine	low	1	0
imipramine	low	1	0
ketamine	low	1	0
mescaline	low	1	0
methylphenidate	medium	3	1
modafinil	low	1	0
nefazodone	medium	1	1
perphenazine	low	1	0
probenecid	low	1	0
risperidone	low	2	0
thioridazine	low	2	0
trazodone	low	1	0
lysergic acid diethylamide	low	12	0
thyroxine	low	1	0
ethinyl estradiol	medium	4	2
apomorphine	low	2	0
levodopa	low	1	0
chloroform	low	2	0
ampicillin	low	3	0
1,1,1-trichloroethane	low	1	0
medroxyprogesterone acetate	medium	36	3
propane	low	4	0
dichlorodifluoromethane	low	1	0
isoprene	low	3	0
4-butyrolactone	low	1	0
butane	low	2	0
1-naphthylamine	medium	2	1
acridines	low	1	0
chlormadinone acetate	low	1	0
cyproterone acetate	medium	29	1
hydantoins	low	1	0
n-pentyl nitrite	low	1	0
medroxyprogesterone	medium	41	3
dihydrotestosterone	low	1	0
methoxyhydroxyphenylglycol	low	1	0
methamphetamine	low	1	0
isobutyl nitrite	low	1	0
lithium carbonate	low	3	0
spectinomycin	low	1	0
s,n,n'-tripropylthiocarbamate	low	2	0
pimozide	low	1	0
benperidol	medium	8	2
cephalexin	low	1	0
bromocriptine	low	3	0
phenyl acetate	low	2	0
tetrachloroethylene	low	1	0
4-methoxyamphetamine	low	11	0
calcium oxalate	low	1	0
paroxetine	low	1	0
pergolide	low	4	0
buserelin	low	2	0
fomesafen	low	2	0
fenoxycarb	low	1	0
haloperidol decanoate	low	1	0
triazoles	medium	1	1
sertraline	medium	4	1
melamine phosphate	low	6	0
oxyprothepine decanoate	low	1	0
valerates	low	1	0
pramipexole	low	3	0
atropine	low	1	0
oxytocin	low	1	0
cocaine	low	1	0
diethylstilbestrol	low	7	0
stilbenes	low	1	0
leuprolide	medium	23	1
pica	low	1	0
lithium	low	11	0
freedom	low	2	0
17-ketosteroids	low	4	0
bilirubin	low	1	0
humulene	low	2	0
cyproterone	medium	51	5
goserelin	low	3	0
fluvoxamine	low	2	0
naltrexone	medium	3	1
whewellite	low	1	0
ergoline	low	1	0
pituitrin	low	1	0
id	low	3	0
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ilys-prolyl-alaninamide	low	1	0
sodium oxybate	low	1	0
sodium ethylxanthate	medium	39	1
quetiapine fumarate	low	1	0
trelstar	medium	13	2
tetracycline	low	2	0
warfarin	low	1	0
rome	low	1	0
exudates	low	1	0
clozapine	low	1	0
vardenafil dihydrochloride	low	1	0
carbidopa	low	3	0
ego	low	38	0

Protein Targets (967)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	19	0	0	19
Chain A, HADH2 protein	11	0	0	11
Chain B, HADH2 protein	11	0	0	11
RAR-related orphan receptor gamma	34	0	0	34
GLI family zinc finger 3	36	0	0	36
AR protein	42	0	0	42
aldehyde dehydrogenase 1 family, member A1	22	0	0	22
thyroid stimulating hormone receptor	19	0	0	19
estrogen receptor 2 (ER beta)	20	0	0	20
nuclear receptor subfamily 1, group I, member 3	33	0	0	33
progesterone receptor	31	0	0	31
glucocorticoid receptor [Homo sapiens]	34	0	0	34
retinoic acid nuclear receptor alpha variant 1	37	0	0	37
estrogen-related nuclear receptor alpha	45	0	0	45
pregnane X nuclear receptor	34	0	0	34
estrogen nuclear receptor alpha	50	0	0	50
aryl hydrocarbon receptor	10	0	0	10
thyroid stimulating hormone receptor	20	0	0	20
activating transcription factor 6	11	0	0	11
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	20	0	0	20
v-jun sarcoma virus 17 oncogene homolog (avian)	24	0	0	24
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	8	0	0	8
thyroid hormone receptor beta isoform 2	33	0	0	33
nuclear factor erythroid 2-related factor 2 isoform 1	38	0	0	38
cytochrome P450 3A4 isoform 1	22	0	0	22
Gamma-aminobutyric acid receptor subunit pi	22	5	0	27
Voltage-dependent calcium channel gamma-2 subunit	22	0	0	22
Gamma-aminobutyric acid receptor subunit beta-1	22	5	0	27
Gamma-aminobutyric acid receptor subunit delta	22	5	0	27
Gamma-aminobutyric acid receptor subunit gamma-2	22	5	0	27
Glutamate receptor 2	22	0	0	22
Gamma-aminobutyric acid receptor subunit alpha-5	22	5	0	27
Gamma-aminobutyric acid receptor subunit alpha-3	22	5	0	27
Gamma-aminobutyric acid receptor subunit gamma-1	22	5	0	27
Gamma-aminobutyric acid receptor subunit alpha-2	22	5	0	27
Gamma-aminobutyric acid receptor subunit alpha-4	22	5	0	27
Gamma-aminobutyric acid receptor subunit gamma-3	22	5	0	27
Gamma-aminobutyric acid receptor subunit alpha-6	22	5	0	27
Gamma-aminobutyric acid receptor subunit alpha-1	22	5	0	27
Gamma-aminobutyric acid receptor subunit beta-3	22	5	0	27
Gamma-aminobutyric acid receptor subunit beta-2	22	5	0	27
Kelch-like ECH-associated protein 1	0	0	1	1
GABA theta subunit	22	5	0	27
Gamma-aminobutyric acid receptor subunit epsilon	22	5	0	27
Histone acetyltransferase KAT8	0	1	0	1
5-hydroxytryptamine receptor 2C	0	27	5	32
5-hydroxytryptamine receptor 2A	0	29	6	35
5-hydroxytryptamine receptor 1A	0	36	4	40
Sodium-dependent noradrenaline transporter	0	37	6	43
Sodium-dependent dopamine transporter	0	24	1	25
5-hydroxytryptamine receptor 1B	0	32	4	36
5-hydroxytryptamine receptor 1D	0	14	4	18
5-hydroxytryptamine receptor 1F	0	14	4	18
5-hydroxytryptamine receptor 2B	0	26	5	31
5-hydroxytryptamine receptor 6	0	7	4	11
Sodium-dependent serotonin transporter	0	45	9	54
Sodium-dependent serotonin transporter	0	19	3	23
5-hydroxytryptamine receptor 7	0	14	4	18
5-hydroxytryptamine receptor 5A	0	7	4	11
5-hydroxytryptamine receptor 5B	0	7	4	11
5-hydroxytryptamine receptor 3A	0	8	4	12
Sodium-dependent dopamine transporter	0	35	4	39
5-hydroxytryptamine receptor 4	0	7	4	11
5-hydroxytryptamine receptor 3B	0	8	4	12
retinoid X nuclear receptor alpha	25	0	0	25
peroxisome proliferator-activated receptor delta	22	0	0	22
Gonadotropin-releasing hormone receptor	0	2	1	3
Chain A, Ferritin light chain	5	0	0	5
thioredoxin reductase	18	0	0	18
TDP1 protein	37	0	0	37
Microtubule-associated protein tau	16	0	0	16
Smad3	8	0	0	8
alpha-galactosidase	4	0	0	4
flap endonuclease 1	2	0	0	2
DNA polymerase iota isoform a (long)	11	0	0	11
DNA topoisomerase 2-alpha	0	0	0	1
Acetylcholinesterase	0	10	1	12
peroxisome proliferator activated receptor gamma	26	0	0	26
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	27	0	0	27
nuclear receptor ROR-gamma isoform 1	12	0	0	12
lamin isoform A-delta10	31	0	0	31
Bromodomain-containing protein 4	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	1	7
Gamma-aminobutyric acid receptor subunit gamma-2	0	6	0	6
Cholecystokinin receptor type A	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-3	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	6	1	7
Gamma-aminobutyric acid receptor subunit beta-2	0	5	0	5
Cholecystokinin receptor type A	0	3	0	3
ATPase family AAA domain-containing protein 5	12	0	0	12
Ataxin-2	24	0	0	24
USP1 protein, partial	17	0	0	17
NFKB1 protein, partial	10	0	0	10
GLS protein	19	0	0	19
cytochrome P450 family 3 subfamily A polypeptide 4	26	0	0	26
cytochrome P450 2D6	27	0	0	27
arylsulfatase A	14	0	0	14
cytochrome P450 2D6 isoform 1	18	0	0	18
D(1A) dopamine receptor	23	0	0	23
chromobox protein homolog 1	25	0	0	25
atrial natriuretic peptide receptor 2 precursor	11	0	0	11
serine/threonine-protein kinase mTOR isoform 1	15	0	0	15
muscarinic acetylcholine receptor M1	18	0	0	18
Solute carrier family 22 member 1	0	14	0	15
Polyunsaturated fatty acid lipoxygenase ALOX15B	12	0	0	12
ATP-binding cassette sub-family C member 3	0	28	0	28
Multidrug resistance-associated protein 4	0	28	0	28
Voltage-dependent L-type calcium channel subunit alpha-1F	0	10	0	10
5-hydroxytryptamine receptor 4	0	34	0	34
Bile salt export pump	0	42	0	42
Albumin	0	0	10	10
High affinity nerve growth factor receptor	0	1	2	3
Aldo-keto reductase family 1 member B1	0	27	0	27
Muscarinic acetylcholine receptor M2	0	22	2	27
Muscarinic acetylcholine receptor M4	0	22	2	26
Muscarinic acetylcholine receptor M1	0	10	1	13
Muscarinic acetylcholine receptor M3	0	9	1	12
Muscarinic acetylcholine receptor M4	0	9	1	12
Muscarinic acetylcholine receptor M5	0	10	1	13
Muscarinic acetylcholine receptor M5	0	23	1	26
Alpha-2A adrenergic receptor	0	31	0	31
Muscarinic acetylcholine receptor M2	0	9	1	13
Muscarinic acetylcholine receptor M1	0	26	2	31
Angiotensin-converting enzyme	0	27	0	27
D(2) dopamine receptor	0	39	8	55
Alpha-2B adrenergic receptor	0	32	0	32
Alpha-2C adrenergic receptor	0	30	0	30
Muscarinic acetylcholine receptor M3	0	24	2	28
D(1A) dopamine receptor	0	27	3	35
D(1B) dopamine receptor	0	10	0	14
UDP-glucuronosyltransferase 1A4	0	0	0	5
Histamine H2 receptor	0	21	2	23
Alpha-1D adrenergic receptor	0	32	0	32
5-hydroxytryptamine receptor 2A	0	40	4	46
5-hydroxytryptamine receptor 2C	0	38	3	41
Histamine H1 receptor	0	9	0	9
Histamine H1 receptor	0	27	3	32
D(3) dopamine receptor	0	35	4	46
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 4 subunit alpha	0	7	0	8
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 2B	0	36	1	37
Alpha-1A adrenergic receptor	0	27	2	29
Histamine H2 receptor	16	6	1	27
D(1A) dopamine receptor	13	2	0	15
5-hydroxytryptamine receptor 6	0	29	0	30
5-hydroxytryptamine receptor 7	0	10	0	10
Voltage-dependent N-type calcium channel subunit alpha-1B	0	4	0	4
Sodium channel protein type 7 subunit alpha	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1D	0	10	0	10
Potassium voltage-gated channel subfamily H member 2	0	37	0	37
Voltage-dependent L-type calcium channel subunit alpha-1S	0	10	0	10
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	10
Sodium channel protein type 5 subunit alpha	0	9	0	9
Sodium channel protein type 9 subunit alpha	0	7	0	7
Sigma non-opioid intracellular receptor 1	0	5	1	6
Nuclear receptor subfamily 3 group C member 3	0	26	0	26
Canalicular multispecific organic anion transporter 1	0	28	0	28
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	33	0	33
Sodium channel protein type 3 subunit alpha	0	5	0	5
Sodium channel protein type 11 subunit alpha	0	5	0	5
Sodium channel protein type 8 subunit alpha	0	5	0	5
Histamine H3 receptor	0	7	0	7
Sodium channel protein type 10 subunit alpha	0	5	0	5
farnesoid X nuclear receptor	18	0	0	18
Solute carrier family 22 member 3	0	3	0	3
Phenylethanolamine N-methyltransferase	0	2	0	2
Cytochrome P450 2A6	0	2	0	2
Substance-P receptor	0	1	0	1
Cytochrome P450 2A5	0	1	0	1
Beta-2 adrenergic receptor	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	10	0	10
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	10	0	0	10
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Cruzipain	5	0	0	5
Beta-lactamase	0	0	0	1
acid sphingomyelinase	1	0	0	1
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
euchromatic histone-lysine N-methyltransferase 2	33	0	0	33
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
DNA polymerase beta	5	0	0	5
DNA polymerase eta isoform 1	3	0	0	3
geminin	29	0	0	29
DNA polymerase kappa isoform 1	7	0	0	7
Carbonic anhydrase 1	0	8	0	10
Carbonic anhydrase 2	0	8	1	11
60 kDa heat shock protein, mitochondrial	0	1	0	1
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	5	0	5
Solute carrier family 15 member 1	0	2	0	2
Spike glycoprotein	25	2	3	30
10 kDa heat shock protein, mitochondrial	0	1	0	1
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	1	0	1
Metallo-b-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
ATP-dependent phosphofructokinase	19	0	0	19
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	12	0	0	12
Chain A, Putative fructose-1,6-bisphosphate aldolase	6	0	0	6
Luciferase	13	0	0	13
acetylcholinesterase	15	0	0	15
phosphopantetheinyl transferase	11	0	0	11
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
regulator of G-protein signaling 4	14	0	0	14
Histone H2A.x	15	0	0	15
cellular tumor antigen p53 isoform a	8	0	0	8
cytochrome P450 2C19 precursor	8	0	0	8
cytochrome P450 2C9 precursor	7	0	0	7
vitamin D3 receptor isoform VDRA	14	0	0	14
potassium voltage-gated channel subfamily H member 2 isoform d	22	0	0	22
mitogen-activated protein kinase 1	16	0	0	16
peripheral myelin protein 22	25	0	0	25
lethal factor (plasmid)	12	0	0	12
Cellular tumor antigen p53	24	0	0	24
Integrin beta-3	7	0	0	7
Integrin alpha-IIb	7	0	0	7
5-hydroxytryptamine receptor 1A	0	15	7	22
Tryptophan 5-hydroxylase 1	0	6	0	6
Alpha-1B adrenergic receptor	0	25	2	27
D	0	19	0	19
D(3) dopamine receptor	0	17	1	18
Alpha-2B adrenergic receptor	0	17	1	18
D(2) dopamine receptor	0	9	0	9
D(4) dopamine receptor	0	18	3	27
Alpha-2C adrenergic receptor	0	17	1	18
Alpha-2A adrenergic receptor	0	17	1	18
Alpha-1D adrenergic receptor	0	18	2	20
D(1B) dopamine receptor	0	15	0	15
D(4) dopamine receptor	0	15	1	16
D(2) dopamine receptor	0	27	5	33
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	3	0	3
D	0	9	0	9
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	2	2
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	2	1	3
glp-1 receptor, partial	10	0	0	10
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	9	0	0	9
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	8	0	0	8
Rap guanine nucleotide exchange factor 3	6	0	0	6
EWS/FLI fusion protein	13	0	0	13
M-phase phosphoprotein 8	12	0	0	12
Zinc finger protein mex-5	0	0	1	1
POsterior Segregation	0	0	1	1
Genome polyprotein	0	1	0	1
Replicase polyprotein 1ab	0	4	3	7
Hexokinase-2	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Inositol monophosphatase 1	8	0	0	8
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Solute carrier organic anion transporter family member 1B1	0	2	0	4
Genome polyprotein	0	1	1	2
dopamine D1 receptor	4	0	0	4
ATAD5 protein, partial	17	0	0	17
Fumarate hydratase	12	0	0	12
G	19	0	0	19
polyprotein	12	0	0	12
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
Interferon beta	25	0	0	25
HLA class I histocompatibility antigen, B alpha chain	19	0	0	19
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	11	0	15
Beta-1 adrenergic receptor	0	5	0	5
Cytochrome P450 3A4	0	13	0	16
Androgen receptor	0	20	1	21
ATP-dependent translocase ABCB1	0	3	0	3
Alpha-synuclein	3	4	0	7
Inositol hexakisphosphate kinase 1	19	0	0	19
cytochrome P450 2C9, partial	19	0	0	19
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	5	4	9
Potassium channel subfamily K member 9	0	1	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	24	0	0	24
Solute carrier family 22 member 2	0	8	0	10
Bile salt export pump	0	9	0	9
Beta-2 adrenergic receptor	0	5	0	5
Angiotensin-converting enzyme	0	1	0	1
Beta-1 adrenergic receptor	0	4	0	4
Beta-3 adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 7	0	10	0	10
5-hydroxytryptamine receptor 3A	0	4	0	4
Alpha-2A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Multidrug and toxin extrusion protein 2	0	6	0	6
Multidrug and toxin extrusion protein 1	0	6	0	6
Lysosomal alpha-glucosidase	0	1	0	1
IDH1	12	0	0	12
thyroid hormone receptor beta isoform a	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
Vpr	3	0	0	3
Major prion protein	0	0	4	4
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	2	0	2
Cytochrome P450 2C9	0	13	0	14
UDP-glucuronosyltransferase 2B7	0	2	0	5
Cytochrome P450 2B6	0	1	1	2
Cytochrome P450 2J2	0	10	0	11
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
Solute carrier family 22 member 6	0	6	0	6
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	5	0	5
Gastrin/cholecystokinin type B receptor	0	2	0	2
SMAD family member 2	6	0	0	6
SMAD family member 3	6	0	0	6
thioredoxin glutathione reductase	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
transcriptional regulator ERG isoform 3	5	0	0	5
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
survival motor neuron protein isoform d	14	0	0	14
neuropeptide S receptor isoform A	5	0	0	5
Glucocorticoid receptor	0	13	1	15
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Cytochrome P450 2C19	0	8	0	10
interleukin 8	8	0	0	8
Nuclear receptor ROR-gamma	9	0	0	9
Proteasome subunit beta type-11	0	0	0	1
Thrombopoietin	7	0	0	7
caspase 7, apoptosis-related cysteine protease	11	0	0	11
NADPH oxidase 1	0	3	0	3
67.9K protein	8	0	0	8
Snq2p	0	0	0	5
caspase-3	11	0	0	11
Adenylate cyclase type 1	0	4	0	4
Caspase-7	7	0	0	7
Spike glycoprotein	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
caspase-3	7	0	0	7
histone deacetylase 9 isoform 3	2	0	0	2
heat shock protein beta-1	8	0	0	8
ras-related protein Rab-9A	9	0	0	9
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	2	3	5
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Epidermal growth factor receptor	0	4	0	4
Albumin	0	2	3	5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	3	0	3
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Major prion protein	0	0	1	1
Cytochrome P450 1A2	0	1	1	3
Tyrosine-protein kinase Fyn	0	5	0	5
Procathepsin L	0	2	3	5
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Cytochrome P450 2D6	0	14	1	17
Polyunsaturated fatty acid lipoxygenase ALOX15	0	5	0	5
Sphingomyelin phosphodiesterase	0	2	0	2
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	6	0	6
Adenylate cyclase type 3	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	4	0	4
Adenylate cyclase type 4	0	4	0	4
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	6	0	6
Histamine H1 receptor	0	3	1	4
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	6	0	6
Pleiotropic ABC efflux transporter of multiple drugs	0	5	0	10
Mu-type opioid receptor	0	15	3	20
Glutamate receptor ionotropic, NMDA 1	0	6	0	7
Adenylate cyclase type 8	0	4	0	4
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	10	2	14
Kappa-type opioid receptor	0	13	1	17
Melanocortin receptor 3	0	2	0	2
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Gastrin/cholecystokinin type B receptor	0	3	0	3
Proteasome subunit alpha type-6	0	0	3	4
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	6	0	7
Glutamate receptor ionotropic, NMDA 2B	0	7	0	8
Glutamate receptor ionotropic, NMDA 2C	0	6	0	7
Adenylate cyclase type 6	0	4	0	4
Adenylate cyclase type 5	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Aldehyde oxidase	0	6	0	8
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	6	0	7
Adenylyl cyclase 7	0	4	0	4
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	6	0	7
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	2	3	5
Glutamate receptor ionotropic, NMDA 3A	0	6	0	7
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Solute carrier family 22 member 1	0	7	0	9
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	6	0	8
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
Potassium-transporting ATPase subunit beta	0	1	0	1
Solute carrier family 22 member 6	0	4	0	4
Solute carrier family 22 member 8	0	5	0	7
Histamine H4 receptor	0	4	2	6
Solute carrier family 22 member 11	0	3	0	4
Solute carrier family 22 member 4	0	2	0	2
NPC intracellular cholesterol transporter 1 precursor	7	0	0	7
Sodium-dependent noradrenaline transporter	0	4	0	4
Aldo-keto reductase family 1 member B1	0	2	0	2
Aromatase	0	1	0	1
Sigma intracellular receptor 2	0	6	0	6
Sodium-dependent serotonin transporter	0	4	0	4
Sodium-dependent dopamine transporter	0	6	0	6
Transporter	0	17	0	17
PPM1D protein	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Trypanothione reductase	0	1	0	1
Envelope glycoprotein	0	0	4	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	4	0	4
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	0	4
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
Chain A, JmjC domain-containing histone demethylation protein 3A	7	0	0	7
5-hydroxytryptamine receptor 3E	0	2	0	2
Beta-1 adrenergic receptor	0	1	0	1
glucocerebrosidase	4	0	0	4
Bloom syndrome protein isoform 1	4	0	0	4
peripheral myelin protein 22 isoform 1	7	0	0	7
transient receptor potential cation channel subfamily V member 1	3	0	0	3
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Adenosine receptor A1	0	4	0	5
5-hydroxytryptamine receptor 2C	0	4	0	4
Alpha-1A adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	3	0	3
Alpha-1B adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 5A	0	3	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
D(2) dopamine receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
D(2) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	0	2
Transporter	0	5	0	5
5-hydroxytryptamine receptor 1A	0	2	0	2
5-hydroxytryptamine receptor 3D	0	2	0	2
5-hydroxytryptamine receptor 3C	0	2	0	2
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Amyloid-beta precursor protein	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
pregnane X receptor	7	0	0	7
Progesterone receptor	0	4	2	6
Androgen receptor	0	8	4	14
Adenosine receptor A2b	0	1	0	1
Adenosine receptor A2a	0	1	0	2
ORF73	0	0	1	1
huntingtin isoform 2	5	0	0	5
Solute carrier family 22 member 3	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Histamine H3 receptor	0	1	0	1
15-lipoxygenase, partial	5	0	0	5
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
serine/threonine-protein kinase PLK1	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
high affinity choline transporter 1 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	1	1	2
Estrogen receptor	0	7	4	12
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Adenosine receptor A3	0	6	0	6
Prostaglandin G/H synthase 1	0	3	0	3
Thromboxane-A synthase	0	1	0	1
Adenosine receptor A2a	0	4	0	4
Adenosine receptor A1	0	2	0	2
Vasopressin V1a receptor	0	4	1	5
Estrogen-related receptor gamma	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
TAR DNA-binding protein 43	5	0	0	5
UDP-glucose 4-epimerase	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Estrogen receptor beta	0	5	4	10
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
Cysteinyl leukotriene receptor 1	0	2	0	2
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
thyrotropin-releasing hormone receptor	1	0	0	1
Plasma kallikrein	0	1	0	2
Sex hormone-binding globulin	0	1	4	5
Progesterone receptor	0	1	0	1
Glucocorticoid receptor	0	1	0	1
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	2	0	2
Sex hormone-binding globulin	0	1	0	1
Aromatase	0	2	0	3
Androgen receptor	0	1	2	3
Mineralocorticoid receptor	0	1	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Angiotensin-converting enzyme	0	0	1	1
Cannabinoid receptor 2	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Neuropeptide FF receptor 2	0	0	0	1
ALK tyrosine kinase receptor	0	1	0	1
N-acetyltransferase Eis	0	3	0	3
endonuclease IV	4	0	0	4
GALC protein	4	0	0	4
nonstructural protein 1	5	0	0	5
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
urokinase-type plasminogen activator precursor	4	0	0	4
plasminogen precursor	4	0	0	4
urokinase plasminogen activator surface receptor precursor	4	0	0	4
Steryl-sulfatase	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 1	0	2	0	3
Mu-type opioid receptor	0	4	2	6
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Mu-type opioid receptor	0	3	2	6
Cytochrome P450 1B1	0	2	0	2
Ghrelin O-acyltransferase	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
Cytochrome P450 2B1	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	5
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Cytochrome P450 2C8	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Beta-3 adrenergic receptor	0	3	0	3
muscleblind-like protein 1 isoform 1	1	0	0	1
Cocaine esterase	0	3	0	4
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Cytochrome P450 1A2	0	1	0	1
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	3	0	3
Acetylcholinesterase	0	2	0	2
Cholinesterase	0	2	0	2
Vascular endothelial growth factor receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Delta-type opioid receptor	0	4	1	6
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Acetylcholinesterase	0	1	0	1
Kappa-type opioid receptor	0	5	0	6
Prolyl endopeptidase	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Cholinesterase	0	3	0	3
Carboxylic ester hydrolase	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
UDP-glucuronosyltransferase 1A9	0	2	0	4
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
C-8 sterol isomerase	0	1	0	1
Delta-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	3	1	4
5-hydroxytryptamine receptor 2A	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Protease	0	3	0	3
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Protein cereblon	0	2	0	2
Gonadotropin-releasing hormone receptor	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
Polyphenol oxidase 2	0	1	0	3
Carbonic anhydrase 12	0	3	0	5
Tyrosine-protein kinase Lck	0	1	0	1
Carbonic anhydrase 3	0	2	0	3
Tyrosinase	0	1	0	1
Carbonic anhydrase 4	0	3	0	5
Carbonic anhydrase 6	0	2	0	4
Carbonic anhydrase 5A, mitochondrial	0	2	1	5
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase 7	0	2	0	4
Carbonic anhydrase	0	1	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase 9	0	3	0	5
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Monocarboxylate transporter 10	0	0	0	1
Carbonic anhydrase 15	0	3	0	4
Carbonic anhydrase 13	0	2	0	4
Carbonic anhydrase 14	0	2	0	4
Carbonic anhydrase 5B, mitochondrial	0	2	0	4
phosphoglycerate kinase	1	0	0	1
Beta-2 adrenergic receptor	0	2	0	2
Catechol O-methyltransferase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1E	0	2	0	2
Sodium-dependent dopamine transporter	0	1	0	1
PINK1	2	0	0	2
Parkin	3	0	0	3
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Histidine decarboxylase	0	0	1	1
Kappa-type opioid receptor	0	2	1	3
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A8	0	0	0	1
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	2	2	4
Vasopressin V1a receptor	0	1	0	1
Vasopressin V1b receptor	0	1	1	2
Vasopressin V1b receptor	0	1	0	1
Oxytocin receptor	0	1	0	1
Oxytocin receptor	0	0	1	1
Vasopressin V2 receptor	0	1	0	1
Myeloperoxidase	0	1	0	1
Quinolone resistance protein NorA	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	1	2
Substance-P receptor	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
P2X purinoceptor 4	0	1	0	1
Rhodopsin kinase GRK1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
bcl-2-related protein A1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Aldehyde oxidase 1	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Aldehyde oxidase 1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Aldehyde oxidase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Amine oxidase [flavin-containing] A	0	2	0	2
Amine oxidase [flavin-containing] B	0	2	0	2
Membrane primary amine oxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
DNA polymerase III, partial	1	0	0	1
XBP1	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
DNA damage-inducible transcript 3 protein	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Ubiquitin carboxyl-terminal hydrolase 1	0	1	0	1
Glycine receptor subunit alpha-1	0	0	2	2
WD repeat-containing protein 48	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Solute carrier family 22 member 8	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	2
Solute carrier family 22 member 7	0	1	0	2
Canalicular multispecific organic anion transporter 1	0	1	0	1
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 7	0	2	0	3
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	1	1	2
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Transcriptional activator protein LuxR	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Free fatty acid receptor 3	0	0	1	1
Tyrosinase	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein-arginine deiminase type-4	0	1	0	1
Cathepsin D	0	1	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Retinoic acid receptor RXR-alpha	0	0	2	2
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
Endolysin	0	0	1	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 4	0	2	0	2
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Carbonic anhydrase	0	1	0	1
Histone deacetylase 3	0	2	0	2
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Histone deacetylase 1	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (438)

Protein Targets (967)

Paraphilias

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (438)

Drugs Studied (136)

Protein Targets (967)