Page last updated: 2024-08-05 11:37:55

3beta-hydroxy steroid

A 3-hydroxy steroid in which the 3-hydroxy substituent is in the beta-position.

ChEBI ID: 36836

Members (29)

MemberDefinitionRole
24-methylene cycloartanolA pentacyclic triterpenoid that is (9beta)-24-methylene-9,19-cyclolanostane which carries a hydroxy group at position 3beta. It is isolated from several plant species including Euphorbia, Epidendrum, Psychotria and Sideritis.24-methylenecycloartanol
5 alpha-androstane-3 beta,17 beta-diolAn androstane-3,17-diol that is 5alpha-androstane substituted by beta-hydroxy groups at positions 3 and 17. It is a metabolite of dihydrotestosterone.5alpha-androstane-3beta,17beta-diol
bufalinA 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the skin of the toad Bufo bufo.bufalin
cerevisterolAn ergostanoid that is (22E)-ergosta-7,22-diene substituted by hydroxy groups at positions 3, 5 and 6 (the 3beta,5alpha,6beta stereoisomer). It has been isolated from the fungus, Xylaria species.cerevisterol
cholest-8(14)-en-3-ol-15-oneA 3beta-hydroxysteroid consisting of 3beta-hydroxy-5alpha-cholest-8(14)-ene having an additional oxo group at the 15-position.3beta-hydroxy-5alpha-cholest-8(14)-en-15-one
cholestane-3,5,6-triol, (3beta, 5alpha, 6beta)-isomer5alpha-cholestane-3beta,5,6beta-triol
cholesterol alpha-oxide5,6alpha-epoxy-5alpha-cholestan-3beta-ol
cyasteronecyasterone
cyclolaudenolA pentacyclic triterpenoid that is (24S)-methyl-9beta,19-cyclolanost-25-ene which carries a hydroxy group at position 3beta. It is isolated from several plant species inclduing Turraeanthus and Tillandsia.cyclolaudenol
digitoxigeninA 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22).digitoxigenin
digoxigeninA hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.digoxigenin
epiandrosteroneA 3beta-hydroxy steroid that is (5alpha)-androstane substituted by a beta-hydroxy group at position 3 and an oxo group at position 17.epiandrosterone
epietiocholanoloneA 3beta-hydroxy steroid that is 5beta-androstane substituted by a hydroxy group at position 3beta and an oxo group at position 17. It is a metabolite of testosterone.epietiocholanolone
ethynodiolethynodiol
ginsenoside f1A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.ginsenoside F1
ginsenoside m1A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.ginsenoside C-K
ginsenoside reA ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.ginsenoside Re
ginsenoside rfA ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.ginsenoside Rf
ginsenoside rg2A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy group at position 6 has been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.ginsenoside Rg2
ginsenoside rh1A tetracyclic triterpenoid that is (20S)-protopanaxadiol which is substituted by beta-D-glucoside at the 6alpha position.(20S)-ginsenoside Rh1
gitoxigeningitoxigenin
gypenoside LXXVA ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position.gypenoside LXXV
notoginsenoside r1A ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.notoginsenoside R1
oleandrigeninA steroid ester that is the 16-acetyl derivative of gitoxigenin.oleandrigenin
ouabageninA hexahydroxy steroidal lactone obtained by hydrolysis of ouabain.ouabagenin
ponasterone aponasterone A
protopanaxatriolA tetracyclic triterpenoid sapogenin (isolated from ginseng and notoginseng) that is that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions and in which a double bond has been introduced at the 24-25 position.protopanaxatriol
strophanthidinstrophanthidin
tomatidineA 3beta-hydroxy steroid resulting from the substitution of the 3beta-hydrogen of tomatidane by a hydroxy group.tomatidine

Research

Studies (3,656)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990706 (19.31)18.7374
1990's1,053 (28.80)18.2507
2000's698 (19.09)29.6817
2010's876 (23.96)24.3611
2020's323 (8.83)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials19 (0.48%)5.53%
Reviews108 (2.73%)6.00%
Case Studies18 (0.46%)4.05%
Observational0 (0.00%)0.25%
Other3,807 (96.33%)84.16%