Page last updated: 2024-08-05 15:12:06

insulin-like growth factor receptor 1 antagonist

An antagonist at the insulin-like growth factor receptor 1.

ChEBI ID: 75252

Members (2)

MemberDefinitionClass
aurintricarboxylic acidA member of the class of quinomethanes that is 3-methylidene-6-oxocyclohexa-1,4-diene-1-carboxylic acid in which the methylidene hydrogens are replaced by 4-carboxy-3-hydroxyphenyl groups. The trisodium salt is the biological stain 'chrome violet CG' while the triammonium salt is 'aluminon'.aurintricarboxylic acid
picropodophyllinAn organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing 3,4,5-trimethoxyphenyl and hydroxy substituents.picropodophyllotoxin

Research

Studies (662)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990161 (24.32)18.7374
1990's195 (29.46)18.2507
2000's133 (20.09)29.6817
2010's134 (20.24)24.3611
2020's39 (5.89)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials3 (0.43%)5.53%
Reviews23 (3.32%)6.00%
Case Studies1 (0.14%)4.05%
Observational0 (0.00%)0.25%
Other665 (96.10%)84.16%

Protein Targets (389)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency3.355212
15-lipoxygenase, partialHomo sapiens (human)Potency1.756012
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseLeishmania major strain FriedlinPotency30.131311
67.9K proteinVaccinia virusPotency2.238711
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency28.183812
Alpha-synucleinHomo sapiens (human)Potency4.109511
ATAD5 protein, partialHomo sapiens (human)Potency29.081011
ATP-dependent phosphofructokinaseTrypanosoma brucei brucei TREU927Potency0.049022
Bloom syndrome protein isoform 1Homo sapiens (human)Potency3.310035
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency1.122011
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency26.651412
Chain A, ATP-DEPENDENT DNA HELICASE Q1Homo sapiens (human)Potency6.746635
Chain A, Beta-lactamaseEscherichia coli K-12Potency8.912522
Chain A, Breast cancer type 1 susceptibility proteinHomo sapiens (human)Potency14.219112
Chain A, CruzipainTrypanosoma cruziPotency19.936923
Chain A, Ferritin light chainEquus caballus (horse)Potency39.810711
Chain A, HADH2 proteinHomo sapiens (human)Potency4.807123
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASEHomo sapiens (human)Potency5.039235
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency35.397311
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency0.029125
Chain B, HADH2 proteinHomo sapiens (human)Potency4.807123
chaperonin-containing TCP-1 beta subunit homologHomo sapiens (human)Potency70.794611
chromobox protein homolog 1Homo sapiens (human)Potency50.099822
ClpPBacillus subtilisPotency21.671211
core-binding factor subunit beta isoform 2Homo sapiens (human)Potency4.860822
cytochrome P450 2C19 precursorHomo sapiens (human)Potency25.118911
cytochrome P450 2C9 precursorHomo sapiens (human)Potency15.848911
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency39.810711
Disintegrin and metalloproteinase domain-containing protein 17Homo sapiens (human)Potency19.952611
DNA polymerase betaHomo sapiens (human)Potency0.022411
DNA polymerase eta isoform 1Homo sapiens (human)Potency0.125911
DNA polymerase III, partialBacillus subtilisPotency3.358711
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency39.741412
DNA polymerase kappa isoform 1Homo sapiens (human)Potency0.375112
endonuclease IVEscherichia coliPotency1.473322
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency29.849311
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency0.416413
EWS/FLI fusion proteinHomo sapiens (human)Potency0.100744
eyes absent homolog 2 isoform aHomo sapiens (human)Potency50.118711
flap endonuclease 1Homo sapiens (human)Potency0.353923
Fumarate hydrataseHomo sapiens (human)Potency0.263511
galactokinaseHomo sapiens (human)Potency14.125411
gemininHomo sapiens (human)Potency35.481311
GLS proteinHomo sapiens (human)Potency2.238712
glucokinase regulatory proteinHomo sapiens (human)Potency10.699233
Glutamate receptor 1Rattus norvegicus (Norway rat)Potency0.056211
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency0.056211
Glutamate receptor 3Rattus norvegicus (Norway rat)Potency0.056211
Glutamate receptor 4Rattus norvegicus (Norway rat)Potency0.056211
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1Homo sapiens (human)Potency15.848911
hexokinase-4 isoform 1Homo sapiens (human)Potency10.699233
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency14.762627
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency0.439212
histone-lysine N-methyltransferase 2A isoform 2 precursorHomo sapiens (human)Potency10.000011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency12.589322
Inositol monophosphatase 1Rattus norvegicus (Norway rat)Potency11.904822
Interferon betaHomo sapiens (human)Potency2.336213
lamin isoform A-delta10Homo sapiens (human)Potency22.387211
lethal factor (plasmid)Bacillus anthracis str. A2012Potency7.875822
lethal(3)malignant brain tumor-like protein 1 isoform IHomo sapiens (human)Potency0.035511
LuciferasePhotinus pyralis (common eastern firefly)Potency23.934111
M-phase phosphoprotein 8Homo sapiens (human)Potency0.207812
Microtubule-associated protein tauHomo sapiens (human)Potency31.716824
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency4.466811
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency9.200011
Ornithine decarboxylaseRattus norvegicus (Norway rat)Potency0.158511
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)Potency0.674611
peripheral myelin protein 22 isoform 1Homo sapiens (human)Potency67.455511
phosphoglycerate kinaseTrypanosoma brucei brucei TREU927Potency0.075711
polyproteinZika virusPotency0.263511
polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)Potency11.220211
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency13.948012
PPM1D proteinHomo sapiens (human)Potency2.336212
pyruvate kinase PKM isoform bHomo sapiens (human)Potency0.158522
regulator of G-protein signaling 4Homo sapiens (human)Potency10.621311
RGS12Homo sapiens (human)Potency15.848911
runt-related transcription factor 1 isoform AML1bHomo sapiens (human)Potency4.860822
Single-stranded DNA cytosine deaminaseHomo sapiens (human)Potency79.373524
TDP1 proteinHomo sapiens (human)Potency0.048022
thioredoxin reductaseRattus norvegicus (Norway rat)Potency34.269225
ThrombopoietinHomo sapiens (human)Potency3.162322
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency8.971622
thyroid stimulating hormone receptorHomo sapiens (human)Potency3.162311
ubiquitin carboxyl-terminal hydrolase 2 isoform aHomo sapiens (human)Potency7.371533
USP1 protein, partialHomo sapiens (human)Potency8.912511
vitamin D3 receptor isoform VDRAHomo sapiens (human)Potency8.912511

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
10 kDa chaperonin Escherichia coliIC500.735022
10 kDa heat shock protein, mitochondrialHomo sapiens (human)IC503.200011
60 kDa chaperoninEscherichia coli K-12IC50250.000011
60 kDa chaperonin Escherichia coliIC500.735022
60 kDa heat shock protein, mitochondrialHomo sapiens (human)IC503.200011
Complement component C9Homo sapiens (human)IC500.500011
CruzipainTrypanosoma cruziIC5040.500022
Cystathionine beta-synthaseHomo sapiens (human)IC50181.800044
Cystathionine gamma-lyaseHomo sapiens (human)IC5094.50001010
Cystathionine gamma-lyaseMus musculus (house mouse)IC5043.200011
Cystathionine gamma-lyaseHomo sapiens (human)Ki0.600011
Cysteine protease ATG4BHomo sapiens (human)IC5010.475044
Delta-type opioid receptorRattus norvegicus (Norway rat)IC501.800011
DNA polymerase etaHomo sapiens (human)IC500.075011
DNA polymerase iotaHomo sapiens (human)IC500.075011
DNA repair protein RAD52 homologHomo sapiens (human)IC505.000011
DNA-(apurinic or apyrimidinic site) endonucleaseHomo sapiens (human)IC503.370033
DNA-3-methyladenine glycosylaseHomo sapiens (human)IC500.200011
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)IC5014.060011
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)IC505.400011
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)IC50282.900011
large T antigenBetapolyomavirus macacaeIC501.930011
Mu-type opioid receptorRattus norvegicus (Norway rat)IC503.300011
Myc proto-oncogene proteinHomo sapiens (human)IC5014.060011
Thiosulfate sulfurtransferaseHomo sapiens (human)IC50100.000011
Tyrosyl-DNA phosphodiesterase 1Homo sapiens (human)IC500.017022

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
26S proteasome regulatory subunit 6BHomo sapiens (human)Kd30.000011
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)Kd30.000011
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)Kd30.000011
5'-AMP-activated protein kinase subunit gamma-2Homo sapiens (human)Kd30.000011
AarF domain-containing protein kinase 1Homo sapiens (human)Kd30.000011
Actin-related protein 2Homo sapiens (human)Kd30.000011
Actin-related protein 3Homo sapiens (human)Kd30.000011
Activated CDC42 kinase 1Homo sapiens (human)Kd30.000011
Activin receptor type-1Homo sapiens (human)Kd30.000011
Activin receptor type-1BHomo sapiens (human)Kd30.000011
Activin receptor type-2BHomo sapiens (human)Kd30.000011
Adenine phosphoribosyltransferaseHomo sapiens (human)Kd30.000011
Adenosine kinaseHomo sapiens (human)Kd30.000011
Adenylate kinase 2, mitochondrialHomo sapiens (human)Kd30.000011
ADP/ATP translocase 2Homo sapiens (human)Kd30.000011
ADP/ATP translocase 3Homo sapiens (human)Kd30.000011
AP2-associated protein kinase 1Homo sapiens (human)Kd30.000011
ATP-dependent 6-phosphofructokinase, platelet typeHomo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX1Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX3XHomo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX42Homo sapiens (human)Kd30.000011
Atypical kinase COQ8A, mitochondrialHomo sapiens (human)Kd30.000011
Aurora kinase AHomo sapiens (human)Kd30.000011
Aurora kinase BHomo sapiens (human)Kd30.000011
Beta-adrenergic receptor kinase 1Homo sapiens (human)Kd30.000011
BMP-2-inducible protein kinaseHomo sapiens (human)Kd30.000011
Bone morphogenetic protein receptor type-1AHomo sapiens (human)Kd30.000011
Bone morphogenetic protein receptor type-1BHomo sapiens (human)Kd30.000011
Bone morphogenetic protein receptor type-2Homo sapiens (human)Kd30.000011
Breakpoint cluster region proteinHomo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase type II-alpha regulatory subunitHomo sapiens (human)Kd30.000011
Casein kinase I isoform alphaHomo sapiens (human)Kd30.000012
Casein kinase I isoform deltaHomo sapiens (human)Kd30.000011
Casein kinase I isoform epsilonHomo sapiens (human)Kd30.000011
Casein kinase I isoform gamma-1Homo sapiens (human)Kd30.000011
Casein kinase I isoform gamma-2Homo sapiens (human)Kd30.000011
Casein kinase I isoform gamma-3Homo sapiens (human)Kd30.000011
Casein kinase II subunit alpha'Homo sapiens (human)Kd30.000011
Cell division cycle 7-related protein kinaseHomo sapiens (human)Kd30.000011
cGMP-dependent protein kinase 1 Homo sapiens (human)Kd30.000012
Chromodomain-helicase-DNA-binding protein 4Homo sapiens (human)Kd30.000011
Citron Rho-interacting kinaseHomo sapiens (human)Kd30.000011
Cyclin-dependent kinase 1Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 10Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 12Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 16Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 17Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 2Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 3Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 4Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 6Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 7Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 9Homo sapiens (human)Kd30.000011
Cyclin-dependent-like kinase 5 Homo sapiens (human)Kd30.000011
Cyclin-G-associated kinaseHomo sapiens (human)Kd30.000011
Cystathionine gamma-lyaseHomo sapiens (human)Kd3.400011
Cysteine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Cytochrome c1, heme protein, mitochondrialHomo sapiens (human)Kd30.000011
dCTP pyrophosphatase 1Homo sapiens (human)Kd30.000011
Delta(24)-sterol reductaseHomo sapiens (human)Kd30.000011
Deoxycytidine kinaseHomo sapiens (human)Kd30.000011
Discoidin domain-containing receptor 2Homo sapiens (human)Kd30.000011
DNA replication licensing factor MCM4Homo sapiens (human)Kd30.000011
DNA topoisomerase 2-alphaHomo sapiens (human)Kd0.486011
DNA topoisomerase 2-betaHomo sapiens (human)Kd30.000011
DnaJ homolog subfamily A member 1Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)Kd30.000011
Dual specificity protein kinase TTKHomo sapiens (human)Kd30.000011
Dual specificity testis-specific protein kinase 1Homo sapiens (human)Kd30.000011
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)Kd30.000011
Dynamin-like 120 kDa protein, mitochondrialHomo sapiens (human)Kd30.000012
EKC/KEOPS complex subunit TP53RKHomo sapiens (human)Kd30.000011
Electron transfer flavoprotein subunit betaHomo sapiens (human)Kd30.000012
Elongation factor Tu, mitochondrialHomo sapiens (human)Kd30.000011
Ephrin type-A receptor 1Homo sapiens (human)Kd30.000011
Ephrin type-A receptor 2Homo sapiens (human)Kd30.000011
Ephrin type-A receptor 4Homo sapiens (human)Kd30.000011
Ephrin type-A receptor 5Homo sapiens (human)Kd30.000011
Ephrin type-A receptor 7Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 2Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 3Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 4Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 6Homo sapiens (human)Kd30.000011
Epidermal growth factor receptorHomo sapiens (human)Kd30.000011
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)Kd30.000012
Eukaryotic translation initiation factor 2-alpha kinase 1Homo sapiens (human)Kd30.000011
Exosome RNA helicase MTR4Homo sapiens (human)Kd30.000011
Ferrochelatase, mitochondrialHomo sapiens (human)Kd30.000011
Fibroblast growth factor receptor 1Homo sapiens (human)Kd30.000011
Focal adhesion kinase 1Homo sapiens (human)Kd30.000011
General transcription and DNA repair factor IIH helicase subunit XPDHomo sapiens (human)Kd30.000011
Glycine--tRNA ligaseHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, brain formHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, liver formHomo sapiens (human)Kd30.000011
Glycogen synthase kinase-3 alphaHomo sapiens (human)Kd30.000011
Glycogen synthase kinase-3 betaHomo sapiens (human)Kd30.000011
GTP-binding nuclear protein RanHomo sapiens (human)Kd30.000011
Guanine nucleotide-binding protein G(i) subunit alpha-2Homo sapiens (human)Kd30.000011
Heme oxygenase 2Homo sapiens (human)Kd30.000011
Hepatocyte growth factor receptorHomo sapiens (human)Kd30.000011
High affinity nerve growth factor receptorHomo sapiens (human)Kd30.000011
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)Kd30.000011
Inosine-5'-monophosphate dehydrogenase 2Homo sapiens (human)Kd30.000011
Insulin receptorHomo sapiens (human)Kd30.000011
Insulin-like growth factor 1 receptorHomo sapiens (human)Kd30.000011
Integrin-linked protein kinaseHomo sapiens (human)Kd30.000011
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)Kd30.000011
Interleukin-1 receptor-associated kinase 3Homo sapiens (human)Kd30.000011
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)Kd30.000011
Isoleucine--tRNA ligase, mitochondrialHomo sapiens (human)Kd30.000011
LIM domain kinase 1Homo sapiens (human)Kd30.000011
LIM domain kinase 2Homo sapiens (human)Kd30.000011
Long-chain-fatty-acid--CoA ligase 5Homo sapiens (human)Kd30.000011
Macrophage-stimulating protein receptorHomo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 2Homo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 5Homo sapiens (human)Kd30.000011
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)Kd30.000012
Maternal embryonic leucine zipper kinaseHomo sapiens (human)Kd30.000011
Membrane-associated progesterone receptor component 1Homo sapiens (human)Kd30.000011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseHomo sapiens (human)Kd30.000011
MidasinHomo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 1Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 10Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 11Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 14Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 15Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 3 Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 7Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 8Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 9Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)Kd30.000012
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 20Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 4Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 2Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)Kd30.000012
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)Kd30.000011
Mitotic checkpoint serine/threonine-protein kinase BUB1Homo sapiens (human)Kd30.000011
Multifunctional protein ADE2Homo sapiens (human)Kd30.000011
Myosin light chain kinase 3Homo sapiens (human)Kd30.000011
Myosin light chain kinase, smooth muscleHomo sapiens (human)Kd30.000011
Myosin-10Homo sapiens (human)Kd30.000011
Myosin-14Homo sapiens (human)Kd30.000011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13Homo sapiens (human)Kd30.000011
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)Kd30.000011
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)Kd30.000011
NUAK family SNF1-like kinase 2Homo sapiens (human)Kd30.000011
Nucleolar GTP-binding protein 1Homo sapiens (human)Kd30.000011
Obg-like ATPase 1Homo sapiens (human)Kd30.000011
Peroxisomal acyl-coenzyme A oxidase 1Homo sapiens (human)Kd30.000011
Peroxisomal acyl-coenzyme A oxidase 3Homo sapiens (human)Kd30.000011
Phenylalanine--tRNA ligase beta subunitHomo sapiens (human)Kd30.000011
Phosphatidylethanolamine-binding protein 1Homo sapiens (human)Kd30.000011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaHomo sapiens (human)Kd30.000012
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaHomo sapiens (human)Kd30.000011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)Kd30.000011
Platelet-derived growth factor receptor betaHomo sapiens (human)Kd30.000011
Probable ATP-dependent RNA helicase DDX6Homo sapiens (human)Kd30.000011
Protein kinase C alpha typeHomo sapiens (human)Kd30.000011
Protein kinase C beta typeHomo sapiens (human)Kd30.000011
Protein kinase C delta typeHomo sapiens (human)Kd30.000011
Protein kinase C iota typeHomo sapiens (human)Kd30.000011
Protein kinase C theta typeHomo sapiens (human)Kd30.000011
Protein-tyrosine kinase 2-betaHomo sapiens (human)Kd30.000012
Protein-tyrosine kinase 6Homo sapiens (human)Kd30.000011
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)Kd30.000011
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)Kd30.000011
Putative heat shock protein HSP 90-beta 2Homo sapiens (human)Kd30.000011
Pyridoxal kinaseHomo sapiens (human)Kd30.000011
Rab-like protein 3Homo sapiens (human)Kd30.000011
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
Ras-related protein Rab-10Homo sapiens (human)Kd30.000011
Ras-related protein Rab-27AHomo sapiens (human)Kd30.000011
Ras-related protein Rab-6AHomo sapiens (human)Kd30.000011
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd30.000011
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000011
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)Kd30.000011
Rho-associated protein kinase 1Homo sapiens (human)Kd30.000012
Rho-associated protein kinase 2Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)Kd30.000012
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase beta-1Homo sapiens (human)Kd30.000011
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)Kd30.000011
RNA cytidine acetyltransferaseHomo sapiens (human)Kd30.000011
S-adenosylmethionine synthase isoform type-2Homo sapiens (human)Kd30.000011
Septin-9Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 10Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 16Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 24Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 26Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 38Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 4Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase A-RafHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase B-rafHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Chk1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase D2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase D3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase ICKHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase LATS1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MARK2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase N1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase N2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek9Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase NLKHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PAK 2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PAK 4Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase pim-1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase pim-2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PLK4Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase SIK2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase SIK3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase STK11Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase TAO1Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase TAO2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase TAO3Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase TBK1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase ULK3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase/endoribonuclease IRE2Homo sapiens (human)Kd30.000011
Signal recognition particle receptor subunit alphaHomo sapiens (human)Kd30.000011
STE20-like serine/threonine-protein kinase Homo sapiens (human)Kd30.000011
STE20-related kinase adapter protein alphaHomo sapiens (human)Kd30.000011
Structural maintenance of chromosomes protein 1AHomo sapiens (human)Kd30.000011
Structural maintenance of chromosomes protein 2Homo sapiens (human)Kd30.000011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrialHomo sapiens (human)Kd30.000011
TGF-beta receptor type-1Homo sapiens (human)Kd30.000011
TGF-beta receptor type-2Homo sapiens (human)Kd30.000011
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)Kd30.000011
Tyrosine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)Kd30.000011
Tyrosine-protein kinase ABL2Homo sapiens (human)Kd30.000011
Tyrosine-protein kinase BTKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase CSKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase FerHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase FRKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase FynHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase HCKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase JAK1Homo sapiens (human)Kd30.000011
Tyrosine-protein kinase LckHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase LynHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase SYKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase TecHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase YesHomo sapiens (human)Kd30.000011
U5 small nuclear ribonucleoprotein 200 kDa helicaseHomo sapiens (human)Kd30.000011
UMP-CMP kinase Homo sapiens (human)Kd30.000012
Uncharacterized protein FLJ45252Homo sapiens (human)Kd30.000011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrialHomo sapiens (human)Kd30.000011
Wee1-like protein kinaseHomo sapiens (human)Kd30.000011

Other Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Cell death-related nuclease 4Caenorhabditis elegansINH100.000011
Cystathionine gamma-lyaseHomo sapiens (human)alphaKi4.200011
Ribonuclease TEscherichia coli K-12INH10.000011