A drug used to treat or prevent microbial infections.
ChEBI ID: 36043
| Member | Definition | Class |
|---|---|---|
| acedapsone | A sulfone that is dapsone in which both of the amino groups been acetylation. An antimicrobial drug, it also has antimalarial activity. | acedapsone |
| streptomycin | A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class | streptomycin |
| sulfabenzamide | A sulfonamide containing a benzamido substituent on nitrogen. An antibacterial/antimicrobial, it is often used in conjunction with sulfathiazole and sulfacetamide as a topical, intravaginal antibacterial preparation. | sulfabenzamide |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 16,833 (83.83) | 18.7374 |
| 1990's | 1,008 (5.02) | 18.2507 |
| 2000's | 920 (4.58) | 29.6817 |
| 2010's | 1,075 (5.35) | 24.3611 |
| 2020's | 244 (1.22) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 371 (1.66%) | 5.53% |
| Reviews | 500 (2.24%) | 6.00% |
| Case Studies | 674 (3.02%) | 4.05% |
| Observational | 3 (0.01%) | 0.25% |
| Other | 20,750 (93.06%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 38.9018 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 3.2643 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 0.2197 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 38.9018 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 6.3096 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 0.7667 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 29.8493 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | IC50 | 1,000.0000 | 2 | 2 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 | 1,800.0000 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | Ki | 560.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | MIC | 11.7400 | 1 | 1 |