A substance used in the prophylaxis or therapy of infectious diseases.
| Member | Definition | Class |
|---|
| acetylcysteine | An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine. | N-acetyl-L-cysteine |
| amdinocillin | A penicillin in which the 6beta substituent is [(azepan-1-yl)methylidene]amino; an extended-spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. | mecillinam |
| amdinocillin pivoxil | A penicillanic acid ester that is the [(2,2-dimethylpropanoyl)oxy]methyl ester and prodrug of mecillinam. | pivmecillinam |
| aminacrine | An aminoacridine that is acridine in which the hydrogen at position 9 is replaced by an amino group. A fluorescent dyd and topical antiseptic agent, it is used (usually as the hydrochloride salt) in eye drops for the treatment of superficial eye infections. | 9-aminoacridine |
| aminocandin | A member of the family of echinocandins that shows broad-spectrum in vitro activity against Aspergillus and Candida spp. | aminocandin |
| benzoylmesaconine | A diterpene alkaloid with formula C31H43NO10 that is isolated from several Aconitum species. | benzoylmesaconine |
| bicozamycin | A commercially important azabicyclic antibiotic obtained from Streptomyces sapporonensis. It inhibits the Rho protein of E. coli. | bicozamycin |
| brodimoprim | An aminopyrimidine that is 2,4-diaminopyrimidine in which the hydrogen at position 5 has been replaced by a 4-bromo-3,5-dimethoxybenzyl group. | brodimoprim |
| cerulenin | An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function. | cerulenin |
| chlorhexidine | A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. | chlorhexidine |
| chlorhexidine | A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge. | chlorhexidine |
| cilofungin | A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycotic agent against Candida albicans. | cilofungin |
| cinoxacin | A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections. | cinoxacin |
| ciprofloxacin | A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. | ciprofloxacin zwitterion; ciprofloxacin |
| ciprofloxacin hydrochloride anhydrous | The anhydrous form of the monohydrochloride salt of ciprofloxacin. | ciprofloxacin hydrochloride (anhydrous) |
| clotrimazole | A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group. | clotrimazole |
| costunolide | A germacranolide with anthelminthic, antiparasitic and antiviral activities. | costunolide |
| cycloguanil | A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil. | cycloguanil |
| cycloserine | A 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and D-alanine--D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis). | D-cycloserine zwitterion; D-cycloserine |
| dapsone | A sulfone that is diphenylsulfone in which the hydrogen atom at the 4 position of each of the phenyl groups is substituted by an amino group. It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. | dapsone |
| emetine | A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties. | emetine |
| fentichlor | An aryl sulfide having two 5-chloro-2-hydroxyphenyl groups attached to sulfur; an antiinfective drug mostly used in veterinary medicine. | fenticlor |
| furazolidone | A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. | furazolidone |
| ganciclovir | An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections. | ganciclovir |
| gatifloxacin | A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes. | gatifloxacin |
| kethoxal | A butanone derivative having two hydroxy substituents at the 1-position and an ethoxy substituent at the 3-position. | 1,1-dihydroxy-3-ethoxy-2-butanone |
| methylamphotericin b | The methyl ester of amphotericin B. | amphotericin B methyl ester |
| micafungin | A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy. | micafungin |
| nifurtoinol | An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group and at position 3 by a hydroxymethyl group. | nifurtoinol |
| nitrofurantoin | An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA. | nitrofurantoin |
| nitroxoline | A monohydroxyquinoline in which the hydroxy group is positioned at C-8 with a nitro group trans to it at C-5. | nitroxoline |
| ornidazole | A C-nitro compound that is 5-nitroimidazole in which the hydrogens at positions 1 and 2 are replaced by 3-chloro-2-hydroxypropyl and methyl groups, respectively. It is used in the treatment of susceptible protozoal infections and for the treatment of anaerobic bacterial infections. | ornidazole |
| oxiconazole | An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and in which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections. | oxiconazole |
| oxolinic acid | A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. | oxolinic acid |
| pefloxacin | A quinolone that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6 and 7 by ethyl, carboxy, fluorine, and 4-methylpiperazin-1-yl groups, respectively. | pefloxacin |
| phenoxyethanol | An aromatic ether that is phenol substituted on oxygen by a 2-hydroxyethyl group. | 2-phenoxyethanol |
| puromycin | An aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome. | puromycin |
| ribavirin | A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses. | ribavirin |
| rosoxacin | A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by an ethyl group at position 1 and by a pyridin-4-yl group at position 7. An antibacterial drug, active against Neisseria gonorrhoeae, it has been used for treating urinary tract infections and certain sexually transmitted diseases. | rosoxacin |
| salicylic acid | A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. | salicylic acid |
| sgd 301-76 | An organic nitrate salt resulting from the reaction of equimolar amounts of oxiconazole and nitric acid. An antifungal agent, it is used in creams and powders for the topical treatment of fungal skin infections. | oxiconazole nitrate |
| solasodine | An oxaspiro compound and steroid alkaloid sapogenin with formula C27H43NO2 found in the Solanum (nightshade) family. It is used as a precursor in the synthesis of complex steroidal compounds such as contraceptive pills. | solasodine |
| sulfacetamide | A sulfonamide that is sulfanilamide acylated on the sulfonamide nitrogen. | sulfacetamide |
| sulfacetamide sodium | An organic sodium salt that is the monohydrate form of sulfacetamide sodium. | sulfacetamide sodium |
| sulfadiazine | A sulfonamide consisting of pyrimidine with a 4-aminobenzenesulfonamido group at the 2-position. | sulfadiazine |
| sulfadimethoxine | A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. | sulfadimethoxine |
| sulfaguanidine | A sulfonamide incorporating a guanidine moiety used to block the synthesis of folic acid; mostly used in veterinary medicine | sulfaguanidine |
| sulfamerazine | A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position. | sulfamerazine |
| sulfameter | A sulfonamide consisting of pyrimidine having a methoxy substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 2-position. | sulfamethoxydiazine |
| sulfamethazine | A sulfonamide consisting of pyrimidine with methyl substituents at the 4- and 6-positions and a 4-aminobenzenesulfonamido group at the 2-position. | sulfamethazine |
| sulfamethizole | A sulfonamide consisting of a 1,3,4-thiadiazole nucleus with a methyl substituent at C-5 and a 4-aminobenzenesulfonamido group at C-2. | sulfamethizole |
| sulfamethoxazole | An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position. | sulfamethoxazole |
| sulfamethoxypyridazine | A sulfonamide consisting of pyridazine having a methoxy substituent at the 6-position and a 4-aminobenzenesulfonamido group at the 3-position. | sulfamethoxypyridazine |
| sulfapyridine | A sulfonamide consisting of pyridine with a 4-aminobenzenesulfonamido group at the 2-position. | sulfapyridine |
| sulfathiazole | A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position. | sulfathiazole |
| sulfisomidine | A sulfonamide consisting of pyrimidine having methyl substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. | sulfisomidine |
| tazobactam | A member of the class of penicillanic acids that is sulbactam in which one of the exocyclic methyl hydrogens is replaced by a 1,2,3-triazol-1-yl group; used (in the form of its sodium salt) in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. | tazobactam |
| tazobactam sodium | An organic sodium salt having tazobactam(1-) as the counterion; used in combination with ceftolozane sulfate for treatment of complicated intra-abdominal infections and complicated urinary tract infections. | tazobactam sodium |
| tosufloxacin, 4-toluene sulfonate | A racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin tosylate. | tosufloxacin tosylate |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 18.1801 | 1 | 8 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 18.3150 | 1 | 6 |
| 67.9K protein | Vaccinia virus | Potency | 17.4837 | 2 | 9 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 51.3775 | 4 | 17 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 29.1786 | 2 | 16 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 27.9365 | 1 | 18 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 34.5529 | 2 | 4 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 11.2346 | 1 | 4 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 3.1623 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 40.7870 | 12 | 122 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 22.0732 | 2 | 11 |
| arylsulfatase A | Homo sapiens (human) | Potency | 16.0064 | 1 | 5 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 14.4201 | 4 | 6 |
| Ataxin-2 | Homo sapiens (human) | Potency | 18.3264 | 2 | 15 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 29.4439 | 2 | 5 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 21.2387 | 2 | 16 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 14.7582 | 2 | 10 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 28.9421 | 1 | 4 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 43.1690 | 1 | 3 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 27.2567 | 1 | 2 |
| caspase-3 | Homo sapiens (human) | Potency | 43.1690 | 1 | 3 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 27.2567 | 1 | 2 |
| Caspase-7 | Homo sapiens (human) | Potency | 22.1060 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 78.7650 | 3 | 31 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 17.4470 | 2 | 6 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 25.1323 | 1 | 12 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 7.0009 | 2 | 2 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 40.2469 | 2 | 9 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 21.7488 | 2 | 6 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 18.7572 | 2 | 4 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 25.6430 | 2 | 10 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 48.0762 | 1 | 7 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 19.8307 | 2 | 10 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 22.4824 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 26.3672 | 2 | 12 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 25.6430 | 2 | 10 |
| chaperonin-containing TCP-1 beta subunit homolog | Homo sapiens (human) | Potency | 70.7946 | 1 | 1 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 63.9773 | 2 | 12 |
| ClpP | Bacillus subtilis | Potency | 0.7079 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 7.1932 | 1 | 5 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 14.5804 | 1 | 11 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 13.4768 | 1 | 10 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 8.2842 | 1 | 5 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 14.1833 | 1 | 5 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 19.5565 | 2 | 33 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 14.7688 | 2 | 19 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 18.7831 | 1 | 18 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 5.8045 | 1 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 20.4801 | 1 | 4 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 54.6609 | 1 | 8 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 28.1460 | 1 | 3 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 0.0206 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 8.3561 | 2 | 3 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 28.8663 | 12 | 132 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 27.2506 | 3 | 21 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 14.4785 | 10 | 112 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 17.8487 | 1 | 25 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 12.6172 | 4 | 19 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 33.1176 | 5 | 26 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 37.1382 | 1 | 7 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 19.2906 | 1 | 5 |
| G | Vesicular stomatitis virus | Potency | 13.4768 | 1 | 10 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 20.1522 | 1 | 17 |
| geminin | Homo sapiens (human) | Potency | 13.8600 | 3 | 30 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 17.8801 | 3 | 36 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 12.2560 | 1 | 7 |
| GLS protein | Homo sapiens (human) | Potency | 20.8954 | 1 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 25.9042 | 2 | 7 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 22.6435 | 5 | 43 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 36.9076 | 1 | 11 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 28.0835 | 2 | 4 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 43.3314 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 35.3246 | 2 | 20 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 13.3364 | 2 | 49 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 9.1557 | 1 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 41.5010 | 2 | 11 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 13.4768 | 1 | 10 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 11.7796 | 3 | 6 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 28.9115 | 2 | 17 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 10.2613 | 3 | 10 |
| IDH1 | Homo sapiens (human) | Potency | 15.2877 | 1 | 8 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 88.8136 | 1 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 13.4768 | 1 | 20 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 7.9433 | 1 | 1 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 11.9851 | 1 | 4 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 11.9851 | 1 | 4 |
| Interferon beta | Homo sapiens (human) | Potency | 20.8350 | 3 | 29 |
| interleukin 8 | Homo sapiens (human) | Potency | 68.8626 | 1 | 8 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 6.1001 | 2 | 24 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 10.1468 | 1 | 5 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 17.7828 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 49.1476 | 2 | 3 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 35.6740 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 19.3456 | 2 | 13 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 22.8987 | 2 | 7 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 10.3410 | 2 | 6 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 12.9259 | 1 | 5 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 6.4776 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 11.4731 | 2 | 6 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 4.3950 | 1 | 6 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 32.1788 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 26.9274 | 4 | 37 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 17.6187 | 1 | 5 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 33.5989 | 2 | 15 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 26.2933 | 1 | 5 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 14.9184 | 2 | 17 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 9.7333 | 1 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 29.1506 | 3 | 41 |
| P53 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 5.0502 | 1 | 4 |
| Parkin | Homo sapiens (human) | Potency | 8.6124 | 2 | 3 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 22.3139 | 2 | 8 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 50.4723 | 1 | 3 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 31.6127 | 5 | 26 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 33.4015 | 5 | 23 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 30.1478 | 1 | 4 |
| PINK1 | Homo sapiens (human) | Potency | 8.3186 | 1 | 2 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.7324 | 1 | 5 |
| polyprotein | Zika virus | Potency | 19.2906 | 1 | 5 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 10.7706 | 1 | 8 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 18.5958 | 1 | 8 |
| PPM1D protein | Homo sapiens (human) | Potency | 25.4391 | 1 | 10 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 23.9265 | 3 | 17 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 48.9052 | 1 | 4 |
| progesterone receptor | Homo sapiens (human) | Potency | 22.5981 | 3 | 18 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 25.1189 | 2 | 3 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 73.5826 | 2 | 3 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 49.8689 | 1 | 3 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 16.3626 | 2 | 44 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 27.5713 | 1 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 20.7810 | 1 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 34.3171 | 3 | 40 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 21.0346 | 4 | 36 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 3.5306 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 26.6795 | 1 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 31.7502 | 2 | 9 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 31.7502 | 2 | 9 |
| Smad3 | Homo sapiens (human) | Potency | 10.7355 | 1 | 5 |
| snurportin-1 | Homo sapiens (human) | Potency | 88.8136 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 21.6968 | 1 | 7 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 19.5699 | 1 | 19 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 12.7058 | 1 | 5 |
| TDP1 protein | Homo sapiens (human) | Potency | 12.3760 | 2 | 56 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 47.7416 | 1 | 3 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 30.0615 | 4 | 15 |
| Thrombopoietin | Homo sapiens (human) | Potency | 18.9338 | 2 | 6 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 12.9407 | 3 | 40 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 27.7978 | 4 | 6 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 25.9886 | 6 | 34 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 24.4526 | 1 | 2 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 33.3781 | 2 | 4 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 25.0320 | 2 | 5 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.7324 | 1 | 5 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.7324 | 1 | 5 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 49.2458 | 2 | 14 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 24.8174 | 2 | 16 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 21.7418 | 4 | 20 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 47.6173 | 1 | 7 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 36.9076 | 1 | 11 |
| Vpr | Human immunodeficiency virus 1 | Potency | 5.6234 | 1 | 1 |
| WRN | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 3.5425 | 5 | 8 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 75.7500 | 4 | 4 |
| 30S ribosomal protein S1 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S10 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S11 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S12 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S13 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S14 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S15 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S16 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S17 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S18 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S19 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S2 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S20 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S21 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S3 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S4 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S5 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S6 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S7 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S8 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 30S ribosomal protein S9 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 14.8731 | 4 | 5 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 6.6476 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 11.6327 | 1 | 2 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 6.6476 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | IC50 | 7.6525 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 3.6000 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | Ki | 2.1862 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 8.1052 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 5.1582 | 1 | 2 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 14.4720 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 7.5810 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 14.4720 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 7.5810 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | IC50 | 6.9410 | 1 | 2 |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | Ki | 2.2097 | 2 | 3 |
| 50S ribosomal protein L1 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L10 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L11 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L13 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L14 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L15 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L16 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L17 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L18 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L19 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L2 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L20 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L21 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L22 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L23 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L24 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L25 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L27 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L28 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L29 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L3 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L30 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L31 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L31 type B | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L32 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L33 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L34 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L35 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L36 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L36 2 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L4 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L5 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L6 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 50S ribosomal protein L7/L12 | Escherichia coli K-12 | IC50 | 0.9000 | 1 | 1 |
| 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase | Plasmodium berghei | IC50 | 12.4100 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 75.7500 | 4 | 4 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 7.6300 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 123.3522 | 2 | 3 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 13.4200 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 7.5500 | 3 | 3 |
| Adenosine receptor A1 | Mus musculus (house mouse) | Ki | 4.4300 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 12.7110 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 7.2730 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 2.6932 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 3.4849 | 2 | 3 |
| Albumin | Homo sapiens (human) | Ki | 5,888,440,000.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 4.9232 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 4.8822 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.6932 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.5223 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 2.6932 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.5223 | 1 | 2 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | IC50 | 15.0120 | 1 | 1 |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | Ki | 7.3790 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 5.3356 | 1 | 3 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 2.0007 | 1 | 3 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 5.9045 | 1 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 2.6956 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 2.1733 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.3156 | 1 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 26.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 112.0000 | 1 | 1 |
| Aminopeptidase N | Homo sapiens (human) | IC50 | 41.0000 | 1 | 1 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 100.0000 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 11.5860 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 7.7240 | 1 | 1 |
| Angiotensin-converting enzyme | Rattus norvegicus (Norway rat) | IC50 | 48.0000 | 1 | 4 |
| Aromatase | Homo sapiens (human) | IC50 | 0.0018 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 12 |
| ATP-dependent 6-phosphofructokinase | Trypanosoma brucei brucei | IC50 | 57.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 52.4000 | 10 | 10 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 4.1500 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 36.9600 | 2 | 2 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | Ki | 21.7000 | 2 | 2 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| B2 bradykinin receptor | Cavia porcellus (domestic guinea pig) | IC50 | 4.8000 | 1 | 1 |
| bcl-2-related protein A1 | Mus musculus (house mouse) | IC50 | 20.0000 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | IC50 | 11.2790 | 1 | 1 |
| Beta-1 adrenergic receptor | Homo sapiens (human) | Ki | 6.5130 | 1 | 1 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | IC50 | 5.9764 | 1 | 2 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Ki | 4.4824 | 1 | 2 |
| Beta-lactamase | Bacillus licheniformis | IC50 | 0.5100 | 1 | 1 |
| Beta-lactamase | Citrobacter freundii | IC50 | 0.9300 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 22.3179 | 19 | 19 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 54.7136 | 11 | 11 |
| Beta-lactamase | Morganella morganii | IC50 | 0.1900 | 1 | 1 |
| Beta-lactamase | Pseudomonas aeruginosa PAO1 | IC50 | 10.8825 | 4 | 4 |
| Beta-lactamase | Staphylococcus aureus | IC50 | 8.7039 | 7 | 7 |
| Beta-lactamase | Enterobacter cloacae | Ki | 170.0000 | 1 | 1 |
| Beta-lactamase | Burkholderia cenocepacia | IC50 | 0.5000 | 1 | 1 |
| Beta-lactamase | Citrobacter freundii | IC50 | 0.0960 | 1 | 1 |
| Beta-lactamase | Citrobacter gillenii | IC50 | 0.0400 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 15.0771 | 7 | 7 |
| Beta-lactamase | Escherichia coli | IC50 | 42.8130 | 4 | 4 |
| Beta-lactamase | Klebsiella pneumoniae | IC50 | 0.0800 | 1 | 1 |
| Beta-lactamase | Pseudomonas aeruginosa | IC50 | 1.3533 | 3 | 3 |
| Beta-lactamase | Pseudomonas luteola | IC50 | 0.0400 | 1 | 1 |
| Beta-lactamase | Salmonella enterica subsp. enterica serovar Westhampton | IC50 | 0.0022 | 1 | 1 |
| Beta-lactamase | Serratia fonticola | IC50 | 6.9000 | 1 | 1 |
| Beta-lactamase | Shouchella clausii | IC50 | 0.0040 | 1 | 1 |
| Beta-lactamase OXA-1 | Escherichia coli | IC50 | 4.8000 | 1 | 1 |
| Beta-lactamase SHV-1 | Escherichia coli | IC50 | 0.2220 | 1 | 1 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | IC50 | 0.1100 | 1 | 1 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | Ki | 0.2200 | 1 | 1 |
| Beta-lactamase TEM | Escherichia coli | IC50 | 0.0785 | 11 | 11 |
| Beta-lactamase TEM | Escherichia coli | Ki | 0.1900 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | IC50 | 24.9733 | 6 | 6 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | IC50 | 0.0170 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | Ki | 0.4362 | 17 | 19 |
| Bile acid receptor | Homo sapiens (human) | IC50 | 3.2400 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 485.4806 | 5 | 36 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 4 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 21.0000 | 1 | 1 |
| Bromodomain-containing protein 4 | Homo sapiens (human) | IC50 | 0.9800 | 2 | 2 |
| C-C chemokine receptor type 4 | Homo sapiens (human) | IC50 | 1.6000 | 1 | 1 |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | IC50 | 6.7731 | 3 | 6 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 12 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | IC50 | 0.3720 | 2 | 2 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | Ki | 74.0000 | 1 | 1 |
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 324.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 91.7624 | 2 | 7 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 144.6394 | 6 | 21 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 161.7929 | 2 | 14 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 165.9500 | 2 | 14 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 164.7214 | 2 | 14 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 7.2000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 99.1600 | 4 | 9 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 149.9537 | 6 | 21 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 32.8520 | 1 | 4 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 224.3786 | 2 | 14 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 161.9571 | 2 | 14 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 209.5929 | 2 | 14 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 186.5214 | 2 | 14 |
| Carbonic anhydrase 6 | Homo sapiens (human) | IC50 | 13.7228 | 1 | 6 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 248.4004 | 4 | 19 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 167.0286 | 2 | 14 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 160.9133 | 3 | 15 |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | IC50 | 19.9526 | 1 | 1 |
| Cathepsin B | Homo sapiens (human) | Ki | 155.2333 | 6 | 6 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 19.1000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.8160 | 1 | 1 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | IC50 | 5.8000 | 1 | 1 |
| Chain A, N-methyl-D-aspartate Receptor Subunit 1 | Rattus norvegicus (Norway rat) | Ki | 241.0000 | 1 | 3 |
| Chain B, Cathepsin B | Homo sapiens (human) | Ki | 154.4000 | 1 | 1 |
| Chymotrypsinogen A | Bos taurus (cattle) | IC50 | 85.0000 | 1 | 1 |
| Class D beta-lactamase | Brachyspira pilosicoli | IC50 | 0.1600 | 1 | 1 |
| Cystathionine gamma-lyase | Homo sapiens (human) | IC50 | 56.1750 | 3 | 4 |
| cysteine protease ATG4B isoform a | Homo sapiens (human) | IC50 | 11.0000 | 1 | 1 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | IC50 | 33.1720 | 1 | 1 |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | Ki | 16.5860 | 1 | 1 |
| Cystine/glutamate transporter | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 2B6 | Homo sapiens (human) | IC50 | 0.1100 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 16.6853 | 2 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 22.6854 | 3 | 4 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 25.5000 | 2 | 2 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 92.3931 | 8 | 10 |
| D-alanine--D-alanine ligase | Enterococcus faecalis V583 | IC50 | 262.0000 | 1 | 1 |
| D(1A) dopamine receptor | Homo sapiens (human) | IC50 | 6.5765 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Ki | 3.2880 | 1 | 2 |
| D(2) dopamine receptor | Homo sapiens (human) | IC50 | 12.1860 | 1 | 1 |
| D(2) dopamine receptor | Homo sapiens (human) | Ki | 4.0620 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 2.3204 | 1 | 2 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 0.7880 | 1 | 2 |
| D(4) dopamine receptor | Homo sapiens (human) | IC50 | 19.9190 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 6.9850 | 1 | 1 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 5.1430 | 1 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | Ki | 1.8131 | 1 | 2 |
| Dihydrofolate reductase | Escherichia coli K-12 | IC50 | 10.4565 | 2 | 2 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 18.0000 | 1 | 1 |
| Dihydrofolate reductase | Pneumocystis carinii | IC50 | 0.5202 | 4 | 4 |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | IC50 | 0.0625 | 2 | 2 |
| Dihydrofolate reductase | Escherichia coli K-12 | Ki | 0.5103 | 2 | 2 |
| Dihydrofolate reductase | Gallus gallus (chicken) | Ki | 14.4762 | 2 | 2 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 14.4885 | 3 | 3 |
| Dihydrofolate reductase | Lacticaseibacillus casei | Ki | 5.8139 | 3 | 3 |
| Dihydrofolate reductase | Pneumocystis carinii | Ki | 36.3776 | 3 | 3 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 | 22.0000 | 1 | 1 |
| Dihydrofolate reductase | Salmonella enterica subsp. enterica serovar Typhi | Ki | 0.0066 | 1 | 1 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 1,037.0000 | 1 | 2 |
| Dihydropteroate synthase | Escherichia coli K-12 | IC50 | 3.6000 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | IC50 | 46.5300 | 1 | 1 |
| DNA gyrase subunit A | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 6.3000 | 1 | 1 |
| DNA gyrase subunit A | Escherichia coli K-12 | IC50 | 5.2296 | 26 | 28 |
| DNA gyrase subunit A | Mycobacterium tuberculosis H37Rv | IC50 | 23.2876 | 6 | 6 |
| DNA gyrase subunit A | Staphylococcus aureus | IC50 | 103.4485 | 20 | 20 |
| DNA gyrase subunit B | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 6.3000 | 1 | 1 |
| DNA gyrase subunit B | Escherichia coli K-12 | IC50 | 0.5577 | 21 | 23 |
| DNA gyrase subunit B | Mycobacterium tuberculosis H37Rv | IC50 | 24.1628 | 2 | 2 |
| DNA gyrase subunit B | Staphylococcus aureus | IC50 | 57.9980 | 15 | 15 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 169.8667 | 3 | 3 |
| DNA topoisomerase 4 subunit A | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 1.7000 | 1 | 1 |
| DNA topoisomerase 4 subunit A | Escherichia coli K-12 | IC50 | 51.0000 | 1 | 1 |
| DNA topoisomerase 4 subunit A | Staphylococcus aureus | IC50 | 5.2191 | 10 | 11 |
| DNA topoisomerase 4 subunit B | Bacillus subtilis subsp. subtilis str. 168 | IC50 | 1.7000 | 1 | 1 |
| DNA topoisomerase 4 subunit B | Staphylococcus aureus | IC50 | 6.4850 | 6 | 6 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | IC50 | 0.0965 | 2 | 2 |
| Endothelin-1 receptor | Homo sapiens (human) | IC50 | 69.0000 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | IC50 | 184.7500 | 3 | 4 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 69.4210 | 1 | 1 |
| exodeoxyribonuclease V subunit RecB | Escherichia coli str. K-12 substr. MG1655 | IC50 | 93.8370 | 2 | 4 |
| exodeoxyribonuclease V subunit RecC | Escherichia coli str. K-12 substr. MG1655 | IC50 | 93.8370 | 2 | 4 |
| exodeoxyribonuclease V subunit RecD | Escherichia coli str. K-12 substr. MG1655 | IC50 | 93.8370 | 2 | 4 |
| Fatty acid synthase | Gallus gallus (chicken) | IC50 | 13.0000 | 1 | 1 |
| Fatty acid synthase | Homo sapiens (human) | IC50 | 9.5460 | 5 | 5 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 50.2050 | 2 | 4 |
| Genome polyprotein | Human rhinovirus sp. | IC50 | 2,500.0000 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | IC50 | 3.2580 | 1 | 1 |
| Glucocorticoid receptor | Homo sapiens (human) | Ki | 1.4810 | 1 | 1 |
| Glucose transporter | Leishmania mexicana | IC50 | 0.0810 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 4.8350 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 2.3000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 192.0000 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 3.2580 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 1.4810 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 3.2580 | 1 | 1 |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 1.4810 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 3.2580 | 1 | 1 |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 1.4810 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | IC50 | 3.2580 | 1 | 1 |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | Ki | 1.4810 | 1 | 1 |
| Heme oxygenase 1 | Rattus norvegicus (Norway rat) | IC50 | 67.5000 | 1 | 2 |
| Heme oxygenase 2 | Rattus norvegicus (Norway rat) | IC50 | 67.5000 | 1 | 2 |
| hepatocyte nuclear factor 4-alpha isoform 2 | Homo sapiens (human) | IC50 | 26.3363 | 2 | 3 |
| hexokinase HKDC1 | Homo sapiens (human) | IC50 | 44.4950 | 2 | 2 |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0900 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | IC50 | 29.4060 | 1 | 1 |
| Histamine H1 receptor | Homo sapiens (human) | Ki | 3.4160 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | IC50 | 5.1650 | 1 | 1 |
| Histamine H2 receptor | Homo sapiens (human) | Ki | 5.0790 | 1 | 1 |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 2,500,000.0000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 0.0965 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 28.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | IC50 | 51.6000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | IC50 | 5.9000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 100.0000 | 1 | 1 |
| Intermediate conductance calcium-activated potassium channel protein 4 | Homo sapiens (human) | IC50 | 0.1667 | 3 | 3 |
| Kappa-type opioid receptor | Homo sapiens (human) | IC50 | 6.3030 | 1 | 1 |
| Kappa-type opioid receptor | Homo sapiens (human) | Ki | 2.5210 | 1 | 1 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | IC50 | 0.1300 | 1 | 1 |
| Malate dehydrogenase, cytoplasmic | Homo sapiens (human) | IC50 | 35.0000 | 1 | 1 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 7.6300 | 1 | 1 |
| melanocortin receptor 4 | Homo sapiens (human) | IC50 | 1.9970 | 1 | 1 |
| Metallo-beta-lactamase L1 type 3 | Stenotrophomonas maltophilia | IC50 | 2,100.0000 | 2 | 2 |
| Metallo-beta-lactamase type 2 | Bacillus cereus | IC50 | 200.0000 | 1 | 1 |
| Metallo-beta-lactamase type 2 | Bacteroides fragilis | IC50 | 2,260.0000 | 5 | 5 |
| Methionine aminopeptidase 1 | Homo sapiens (human) | IC50 | 15.0000 | 1 | 1 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 0.0550 | 2 | 2 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 1.8020 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | IC50 | 6.0000 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 0.7310 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 250.3500 | 1 | 2 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 0.5000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 123.6583 | 1 | 12 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | IC50 | 5.8027 | 1 | 2 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 1.3973 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | IC50 | 14.5310 | 1 | 1 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | Ki | 5.1670 | 1 | 1 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | IC50 | 7.2295 | 1 | 2 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | Ki | 1.5322 | 1 | 2 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | IC50 | 11.7560 | 1 | 1 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | Ki | 1.6400 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 0.4200 | 1 | 1 |
| Nicotinate phosphoribosyltransferase | Homo sapiens (human) | Ki | 0.0002 | 1 | 1 |
| nonstructural protein 1 | Influenza A virus (A/California/07/2009(H1N1)) | IC50 | 4.7230 | 1 | 1 |
| Nuclear receptor subfamily 1 group I member 3 | Homo sapiens (human) | IC50 | 0.2900 | 3 | 3 |
| Nuclear receptor subfamily 1 group I member 3 | Homo sapiens (human) | Ki | 0.1000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 2.2083 | 2 | 3 |
| perilipin-5 | Homo sapiens (human) | IC50 | 4.0045 | 4 | 6 |
| Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | Homo sapiens (human) | Ki | 0.3250 | 1 | 2 |
| phospholipase A2 precursor | Homo sapiens (human) | IC50 | 15.2000 | 1 | 1 |
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | IC50 | 8.9620 | 1 | 1 |
| Platelet-activating factor receptor | Homo sapiens (human) | IC50 | 35.0380 | 1 | 1 |
| Platelet-activating factor receptor | Homo sapiens (human) | Ki | 22.6350 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 3,160.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 100.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily A member 3 | Homo sapiens (human) | IC50 | 6.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 371.9964 | 10 | 16 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Potassium-transporting ATPase alpha chain 1 | Sus scrofa (pig) | IC50 | 5.2000 | 1 | 1 |
| Potassium-transporting ATPase subunit beta | Sus scrofa (pig) | IC50 | 5.2000 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 2,300.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 270.0000 | 2 | 2 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 40.8980 | 2 | 2 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 2.5000 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | Ki | 0.0101 | 1 | 1 |
| Protein arginine N-methyltransferase 6 | Homo sapiens (human) | IC50 | 430.0000 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 | 10,000.0000 | 1 | 2 |
| Prothrombin | Homo sapiens (human) | Ki | 0.0950 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 4,400.0000 | 1 | 1 |
| Puromycin-sensitive aminopeptidase | Homo sapiens (human) | IC50 | 6.0750 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 66.4050 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 0.4450 | 2 | 2 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | Ki | 35.0000 | 1 | 1 |
| Serine hydrolase RBBP9 | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Serum paraoxonase/arylesterase 1 | Homo sapiens (human) | Ki | 86.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 4.1182 | 1 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 3.2719 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 4.9232 | 1 | 2 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 4.8822 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 3.2800 | 1 | 2 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 1.7426 | 1 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | IC50 | 0.1080 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 6.0900 | 2 | 2 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 43.8258 | 1 | 2 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | IC50 | 0.4100 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | IC50 | 280.0000 | 1 | 1 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 144.7720 | 1 | 2 |
| Solute carrier family 22 member 6 | Rattus norvegicus (Norway rat) | Ki | 1,113.6667 | 3 | 3 |
| Solute carrier family 22 member 8 | Homo sapiens (human) | Ki | 1,020.0000 | 1 | 1 |
| Spermine oxidase | Homo sapiens (human) | Ki | 0.3250 | 1 | 2 |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Homo sapiens (human) | Ki | 0.0815 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 6.6859 | 1 | 2 |
| Substance-K receptor | Homo sapiens (human) | Ki | 2.2284 | 1 | 2 |
| Substance-P receptor | Homo sapiens (human) | IC50 | 16.0370 | 1 | 1 |
| Substance-P receptor | Homo sapiens (human) | Ki | 8.7470 | 1 | 1 |
| Synaptojanin-1 | Homo sapiens (human) | IC50 | 15.9000 | 2 | 2 |
| Synaptojanin-2 | Homo sapiens (human) | IC50 | 10.0000 | 3 | 3 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 0.3157 | 1 | 2 |
| Thymidine kinase | Macacine alphaherpesvirus 1 | IC50 | 800.0000 | 1 | 1 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | IC50 | 6.3570 | 1 | 1 |
| Transcriptional activator Myb | Gallus gallus (chicken) | IC50 | 30.6751 | 1 | 2 |
| Transcriptional activator protein LasR | Pseudomonas aeruginosa PAO1 | IC50 | 9.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily M member 2 | Homo sapiens (human) | IC50 | 3.0000 | 2 | 2 |
| Transitional endoplasmic reticulum ATPase | Homo sapiens (human) | IC50 | 4.9000 | 3 | 3 |
| Trypanothione reductase | Trypanosoma cruzi | Ki | 20.0000 | 2 | 2 |
| Trypsin-1 | Homo sapiens (human) | Ki | 1.3500 | 1 | 1 |
| Trypsin-2 | Homo sapiens (human) | Ki | 1.3500 | 1 | 1 |
| Trypsin-3 | Homo sapiens (human) | Ki | 1.3500 | 1 | 1 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 31.8510 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Ki | 19,400.0000 | 1 | 1 |
| Tyrosine-protein phosphatase YopH | Yersinia pseudotuberculosis IP 32953 | Ki | 1,000.0000 | 1 | 1 |
| Tyrosyl-DNA phosphodiesterase 1 | Homo sapiens (human) | IC50 | 18,000.0000 | 1 | 1 |
| ubiquitin-conjugating enzyme E2 N | Homo sapiens (human) | IC50 | 2.6045 | 2 | 2 |
| Ubiquitin-like domain-containing CTD phosphatase 1 | Homo sapiens (human) | IC50 | 66,000.0000 | 1 | 1 |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Escherichia coli K-12 | IC50 | 50.0000 | 1 | 2 |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase | Pseudomonas aeruginosa PAO1 | IC50 | 50.0000 | 1 | 2 |
| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | Staphylococcus epidermidis RP62A | IC50 | 300.0000 | 1 | 1 |
| Uracil-DNA glycosylase | Vaccinia virus WR | IC50 | 38.5000 | 1 | 1 |
| Vasopressin V2 receptor | Homo sapiens (human) | IC50 | 9.0402 | 2 | 4 |
| Vif | Human immunodeficiency virus 1 | IC50 | 46.5300 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 0.5900 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 311.5450 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 0.5900 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 622.5000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 622.5000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 622.5000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Ki | 100,000.0000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 14-alpha sterol demethylase | Aspergillus fumigatus | Kd | 0.1030 | 1 | 1 |
| amino acid transporter AGP1 | Saccharomyces cerevisiae S288C | EC50 | 5.9800 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 36.5217 | 1 | 3 |
| bcl-2-like protein 11 isoform 1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| beta-2 adrenergic receptor | Homo sapiens (human) | EC50 | 4.6900 | 1 | 1 |
| calcineurin A1, putative | Candida dubliniensis CD36 | EC50 | 180.0000 | 1 | 3 |
| Chain A, BCL-2-RELATED PROTEIN A1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| citrate synthase 2, partial | Saccharomyces cerevisiae (brewer's yeast) | EC50 | 14,600.0000 | 1 | 2 |
| Cytochrome P450 130 | Mycobacterium tuberculosis CDC1551 | Kd | 9.7000 | 1 | 2 |
| Cytochrome P450 130 | Mycobacterium tuberculosis H37Rv | Kd | 10.9000 | 2 | 3 |
| Cytochrome P450 144 | Mycobacterium tuberculosis CDC1551 | Kd | 3.1567 | 1 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Kd | 0.0730 | 1 | 1 |
| Dihydrofolate reductase | Escherichia coli K-12 | Kd | 11.7700 | 1 | 1 |
| Estrogen receptor | Rattus norvegicus (Norway rat) | EC50 | 150.0000 | 1 | 4 |
| Estrogen receptor beta | Rattus norvegicus (Norway rat) | EC50 | 150.0000 | 1 | 4 |
| Genome polyprotein | Human enterovirus 71 (strain BRCR) | EC50 | 100.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | EC50 | 2.9500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | EC50 | 2.9500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | EC50 | 2.9500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | EC50 | 10.5250 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | EC50 | 2.9500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | EC50 | 2.9500 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | EC50 | 2.9500 | 1 | 1 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 300.0000 | 1 | 1 |
| heat shock protein 90 | Candida albicans | EC50 | 84.9684 | 3 | 11 |
| High mobility group protein B1 | Homo sapiens (human) | Kd | 1.0000 | 2 | 2 |
| Lanosterol 14-alpha demethylase | Mycobacterium tuberculosis H37Rv | Kd | 0.2000 | 1 | 1 |
| LAP4 | Saccharomyces cerevisiae (brewer's yeast) | EC50 | 2.6430 | 2 | 3 |
| Multidrug resistance protein MdtK | Escherichia coli K-12 | Kd | 90.9000 | 1 | 1 |
| Mycocyclosin synthase | Mycobacterium tuberculosis H37Rv | Kd | 0.0730 | 1 | 1 |
| NPYLR7B | Aedes aegypti (yellow fever mosquito) | EC50 | 20.0000 | 1 | 1 |
| NS5 | Zika virus | EC50 | 6.9539 | 3 | 3 |
| Polymerase acidic protein | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | EC50 | 78.4500 | 4 | 4 |
| Polymerase basic protein 2 | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | EC50 | 20.0000 | 2 | 2 |
| Procathepsin L | Homo sapiens (human) | EC50 | 36.5217 | 1 | 3 |
| Protease | Human immunodeficiency virus 1 | Kd | 0.5770 | 1 | 1 |
| Protein argonaute-2 | Homo sapiens (human) | Kd | 26.6500 | 1 | 2 |
| Purine nucleoside phosphorylase | Mycobacterium tuberculosis H37Rv | Kd | 15.8489 | 1 | 1 |
| recombinase A | Mycobacterium tuberculosis H37Rv | EC50 | 19.7150 | 2 | 2 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 36.5217 | 1 | 3 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 36.5217 | 1 | 3 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 36.5217 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 36.5217 | 1 | 3 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 36.5217 | 1 | 3 |
| RNA-directed RNA polymerase catalytic subunit | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | EC50 | 21.2667 | 3 | 3 |
| RPL19A | Saccharomyces cerevisiae (brewer's yeast) | EC50 | 25.3600 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 36.5217 | 1 | 3 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 36.5217 | 1 | 3 |
| Steroid C26-monooxygenase | Mycobacterium tuberculosis CDC1551 | Kd | 4.7925 | 2 | 8 |
| Sterol 14-alpha demethylase | Aspergillus fumigatus Af293 | Kd | 4.7900 | 1 | 1 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 44.9929 | 2 | 7 |
| Stromelysin-1 | Homo sapiens (human) | Kd | 25,000.0000 | 1 | 1 |
| Taste receptor type 2 member 46 | Homo sapiens (human) | EC50 | 8.6000 | 1 | 1 |
| Trace amine-associated receptor 5 | Mus musculus (house mouse) | EC50 | 10.0000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 36.5217 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 30S ribosomal protein S1 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S10 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S11 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S12 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S13 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S14 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S15 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S16 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S17 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S18 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S19 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S2 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S20 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S21 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S3 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S4 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S5 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S6 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S7 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S8 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 30S ribosomal protein S9 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-2 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit gamma-3 | Homo sapiens (human) | A0.5 | 1,000.0000 | 1 | 1 |
| 50S ribosomal protein L1 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L10 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L11 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L13 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L14 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L15 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L16 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L17 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L18 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L19 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L2 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L20 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L21 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L22 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L23 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L24 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L25 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L27 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L28 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L29 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L3 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L30 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L31 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L31 type B | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L32 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L33 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L34 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L35 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L36 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L36 2 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L4 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L5 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L6 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| 50S ribosomal protein L7/L12 | Escherichia coli K-12 | Km | 234.0000 | 1 | 1 |
| Adenosylhomocysteinase | Homo sapiens (human) | Kinact | 266.0000 | 1 | 1 |
| Adenosylhomocysteinase | Homo sapiens (human) | KR | 407.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Km | 6.0000 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | Km | 300.0000 | 1 | 1 |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | Km | 875.0000 | 1 | 1 |
| Beta-lactamase OXA-1 | Escherichia coli | Kinact | 380.0000 | 1 | 1 |
| CAAX prenyl protease | Saccharomyces cerevisiae S288C | AC50 | 5.6940 | 1 | 1 |
| Caspase 6, apoptosis-related cysteine peptidase | Homo sapiens (human) | AC50 | 14.8600 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | K | 30.0000 | 1 | 1 |
| DNA gyrase subunit A | Escherichia coli K-12 | Activity | 10.7200 | 4 | 4 |
| DNA gyrase subunit A | Staphylococcus aureus | CC50 | 56.9500 | 3 | 6 |
| DNA gyrase subunit A | Escherichia coli K-12 | EC | 1.2000 | 1 | 1 |
| DNA gyrase subunit B | Escherichia coli K-12 | Activity | 0.4000 | 1 | 1 |
| DNA gyrase subunit B | Staphylococcus aureus | CC50 | 2.8500 | 1 | 2 |
| DNA gyrase subunit B | Escherichia coli K-12 | EC | 1.2000 | 1 | 1 |
| DNA repair protein RAD52 homolog isoform a | Homo sapiens (human) | AC50 | 1.7000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Activity | 104.0000 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | CC50 | 150.0000 | 1 | 2 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | EC2 | 150.0000 | 1 | 1 |
| DNA topoisomerase 4 subunit A | Staphylococcus aureus | CC50 | 0.3000 | 1 | 2 |
| DNA topoisomerase 4 subunit B | Staphylococcus aureus | CC50 | 0.3000 | 1 | 2 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | MIC | 0.3000 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | MIC | 5.4850 | 2 | 2 |
| Epoxide hydrolase 1 | Rattus norvegicus (Norway rat) | E100 | 6.2000 | 1 | 1 |
| Estrogen receptor | Mus musculus (house mouse) | Kis | 19,400.0000 | 1 | 4 |
| Estrogen receptor beta | Mus musculus (house mouse) | Kis | 19,400.0000 | 1 | 4 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki' | 210.0000 | 1 | 1 |
| glycogen synthase kinase-3 alpha | Homo sapiens (human) | AC50 | 162.8000 | 1 | 1 |
| heat shock protein 90, putative | Plasmodium falciparum 3D7 | AC50 | 1.6393 | 1 | 3 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | AC50 | 1.7677 | 1 | 3 |
| HSP40, subfamily A [Plasmodium falciparum 3D7] | Plasmodium falciparum 3D7 | AbsAC1000_uM | 0.3870 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | MIC | 0.3000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | INH | 1,000.0000 | 1 | 1 |
| Metallo-b-lactamase | Pseudomonas aeruginosa | Km | 3,500.0000 | 1 | 1 |
| MSH | Drosophila melanogaster (fruit fly) | AC50 | 48.6900 | 1 | 1 |
| PAX8 | Homo sapiens (human) | AC50 | 18.6860 | 5 | 5 |
| Polyphenol oxidase 2 | Agaricus bisporus | ID50 | 3,900.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | INH | 18.0000 | 1 | 1 |
| POU domain, class 2, transcription factor 2 | Homo sapiens (human) | Km | 264.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC60 | 6.9000 | 1 | 1 |
| protein AF-9 isoform a | Homo sapiens (human) | AC50 | 5.2700 | 1 | 1 |
| replicative DNA helicase | Mycobacterium tuberculosis H37Rv | AC50 | 8.2775 | 2 | 2 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Km | 516.2000 | 1 | 1 |
| Solute carrier family 22 member 6 | Homo sapiens (human) | Km | 895.5000 | 1 | 1 |
| Solute carrier family 22 member 7 | Rattus norvegicus (Norway rat) | Km | 85.0000 | 2 | 2 |
| Transcription factor p65 | Homo sapiens (human) | IC100 | 50.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Activity | 19,400.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | Kis | 19,400.0000 | 1 | 1 |