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hemiaminal

Any organic amino compound that has an amino group and a hydroxy group attached to the same carbon atom. Hemiaminals are intermediates in the formation of imines by addition of an amine to an aldehyde or ketone; those derived from primary amines are particularly unstable.

ChEBI ID: 73080

Members (6)

MemberDefinitionRole
ecteinascidin 743A tetrahydroisoquinoline alkaloid obtained from a Caribbean tunicate Ecteinascidia turbinata. Used for the treatment of soft tissue sarcoma and relapsed ovarian cancer.trabectedin
kt 5720An organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of hexyl (3S)-3-hydroxy-2-methyltetrahydrofuran-3-carboxylate (the 2R,3S,5S product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling to positions 3 and 4 of 1,5-dihydro-2H-pyrrol-2-one.KT 5720
kt 5823An organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of methyl (3R)-3-methoxy-2-methyltetrahydrofuran-3-carboxylate (the 2S,3R,5R product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling to positions 3 and 4 of 1-methyl-1,5-dihydro-2H-pyrrol-2-one.KT 5823
kt 5926An organic heterooctacyclic compound that is 5-propoxy-1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of methyl (3R)-3-hydroxy-2-methyltetrahydrofuran-3-carboxylate (the 2S,3R,5R product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling to positions 3 and 4 of 1,5-dihydro-2H-pyrrol-2-one.KT 5926
sibiromycinAn aminoglycoside antibiotic produced by Streptosporangium sibiricum that also exhibits antitumour properties.sibiromycin
vincaminevincamine

Research

Studies (1,656)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990189 (11.41)18.7374
1990's246 (14.86)18.2507
2000's576 (34.78)29.6817
2010's529 (31.94)24.3611
2020's116 (7.00)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials130 (7.45%)5.53%
Reviews174 (9.97%)6.00%
Case Studies67 (3.84%)4.05%
Observational6 (0.34%)0.25%
Other1,369 (78.41%)84.16%