Page last updated: 2024-09-27

Dysplastic Nevus Syndrome

Clinically atypical nevi (usually exceeding 5 mm in diameter and having variable pigmentation and ill defined borders) with an increased risk for development of non-familial cutaneous malignant melanoma. Biopsies show melanocytic dysplasia. Nevi are clinically and histologically identical to the precursor lesions for melanoma in the B-K mole syndrome. (Stedman, 25th ed)

Synonyms(1)

Synonym
Dysplastic Nevus Syndrome

Research

Studies (70)

TimeframeStudies, This Condition (%)All Conditions %
pre-19908 (11.43)23.3326
1990's25 (35.71)12.5806
2000's16 (22.86)18.1394
2010's17 (24.29)28.8240
2020's4 (5.71)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low30
formaldehyde0low20
dihydroxyphenylalanine0low20
candesartan0low10
eflornithine0low10
fluorouracil0low20
hydrochlorothiazide0low10
2-propanol0low30
4-nitroquinoline-1-oxide0low20
tyrosine0low10
methylene blue0medium11
valine0low10
arsenic trioxide0low10
silver0low10
gold0low10
transferrin0low10
glutamic acid0low10
substance p0low10
imiquimod0low10
5-methylcytosine0low10
5-hydroxymethylcytosine0low10
calpeptin0low10
melanotan-ii0low20
pyrimidine dimers0low30
perindopril0low10
imatinib mesylate0low10
singlet oxygen0low10
tretinoin0medium43
bromochloroacetic acid0low10
enclomiphene0low10
ranitidine0low10
beta carotene0medium21
isotretinoin0low10
arsenic0low10
enalapril0low10
mart-1 antigen0low50
cysteinyldopa0low20
atrial natriuretic factor0low10
oligonucleotides0low10
calpain0low10
plx40320medium41
interleukin-80low10
tetracycline0medium11
transforming growth factor beta0low10
cyclin d10low30
transforming growth factor alpha0low30
cyclosporine0low10
eye0low10

Protein Targets (866)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit5005
RAR-related orphan receptor gamma9009
GLI family zinc finger 39009
AR protein130013
aldehyde dehydrogenase 1 family, member A19009
retinoic acid nuclear receptor alpha variant 1110011
retinoid X nuclear receptor alpha9009
estrogen nuclear receptor alpha170017
peroxisome proliferator-activated receptor delta6006
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x4004
thyroid hormone receptor beta isoform a5005
heat shock protein beta-14004
nuclear factor erythroid 2-related factor 2 isoform 19009
lamin isoform A-delta107007
Voltage-dependent calcium channel gamma-2 subunit7007
Glutamate receptor 282111
TDP1 protein150015
glucocorticoid receptor [Homo sapiens]120012
peroxisome proliferator activated receptor gamma7007
nuclear receptor subfamily 1, group I, member 21001
thyroid hormone receptor beta isoform 2100010
Cellular tumor antigen p53100010
Atrial natriuretic peptide receptor 10011
Atrial natriuretic peptide receptor 1 0011
core protein, partial0101
geminin120012
peripheral myelin protein 228008
histone acetyltransferase KAT2A isoform 15005
Bile salt export pump011011
Solute carrier organic anion transporter family member 1B30202
Solute carrier organic anion transporter family member 1B10303
nuclear receptor subfamily 1, group I, member 3100010
thyroid stimulating hormone receptor5005
Nuclear receptor ROR-gamma2114
PPM1D protein2002
Microtubule-associated protein tau7007
regulator of G-protein signaling 45005
vitamin D3 receptor isoform VDRA4004
survival motor neuron protein isoform d6006
Calpain-90101
Interferon beta4004
Calpain-1 catalytic subunit0202
Procathepsin L0101
Cathepsin B0101
Replicase polyprotein 1ab0101
Replicase polyprotein 1ab0101
Cathepsin K0101
acetylcholinesterase6006
USP1 protein, partial5005
cytochrome P450 family 3 subfamily A polypeptide 46006
estrogen-related nuclear receptor alpha8008
pregnane X nuclear receptor8008
cytochrome P450 2D64004
potassium voltage-gated channel subfamily H member 2 isoform d2002
Epidermal growth factor receptor0516
Receptor tyrosine-protein kinase erbB-20202
Aldo-keto reductase family 1 member B10404
Cytochrome P450 3A40214
60 kDa chaperonin0202
Adenosine receptor A30808
60 kDa heat shock protein, mitochondrial0303
Cytochrome P450 2C9 0213
Beta-3 adrenergic receptor0404
Alpha-1B adrenergic receptor010010
Alpha-2B adrenergic receptor0606
5-hydroxytryptamine receptor 1A0202
Sodium-dependent noradrenaline transporter 0415
Thromboxane-A synthase 0101
Type-1A angiotensin II receptor 0011
Type-1 angiotensin II receptor0203
Type-1 angiotensin II receptor0101
Alpha-1A adrenergic receptor010010
Type-2 angiotensin II receptor0101
10 kDa heat shock protein, mitochondrial0303
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Leukotriene B4 receptor 20011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
endonuclease IV3003
15-lipoxygenase, partial1001
Bloom syndrome protein isoform 14004
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
mitogen-activated protein kinase 13003
DNA polymerase kappa isoform 14004
Glutamate receptor 11214
Glutamate receptor 31214
Glutamate receptor 41214
Caspase-71001
euchromatic histone-lysine N-methyltransferase 28008
chromobox protein homolog 15005
Ornithine decarboxylase0102
Mitochondrial 2-oxodicarboxylate carrier0101
farnesoid X nuclear receptor6006
Angiotensin-converting enzyme 0202
Angiotensin-converting enzyme0101
Type-2 angiotensin II receptor0101
Succinyl-diaminopimelate desuccinylase0101
Solute carrier family 15 member 10101
Solute carrier organic anion transporter family member 1A10001
Angiotensin-converting enzyme0101
Solute carrier family 15 member 10101
Multidrug and toxin extrusion protein 10101
Angiotensin-converting enzyme 2 0101
Chain A, Beta-lactamase4004
Chain A, JmjC domain-containing histone demethylation protein 3A2002
glp-1 receptor, partial5005
chaperonin-containing TCP-1 beta subunit homolog3003
phosphopantetheinyl transferase4004
Smad32002
bromodomain adjacent to zinc finger domain 2B3003
IDH15005
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0002
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
nuclear receptor ROR-gamma isoform 14004
5-hydroxytryptamine receptor 40202
Estrogen receptor0202
Tyrosine-protein kinase Fyn0112
Muscarinic acetylcholine receptor M20303
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Cytochrome P450 2D60112
Muscarinic acetylcholine receptor M10202
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
Substance-K receptor0404
Prostaglandin G/H synthase 10202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Sodium-dependent serotonin transporter0202
C-8 sterol isomerase0101
D(3) dopamine receptor0202
Alpha-synuclein2204
5-hydroxytryptamine receptor 2B0606
5-hydroxytryptamine receptor 60202
Sodium-dependent dopamine transporter 0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sigma non-opioid intracellular receptor 10202
Chain A, Uracil Phosphoribosyltransferase0101
Luciferase5005
interleukin 81001
Skn7p0001
thioredoxin reductase6006
pregnane X receptor3003
ATAD5 protein, partial4004
Thrombopoietin1001
thyroid stimulating hormone receptor2002
estrogen receptor 2 (ER beta)7007
progesterone receptor4004
EWS/FLI fusion protein4004
nonstructural protein 12002
67.9K protein2002
arylsulfatase A2002
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta1001
nuclear factor erythroid 2-related factor 2 isoform 24004
huntingtin isoform 22002
flap endonuclease 12002
serine/threonine-protein kinase mTOR isoform 13003
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Vpr2002
muscleblind-like protein 1 isoform 12002
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 40808
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1203
Thymidylate synthase0101
Aromatase0101
Canalicular multispecific organic anion transporter 10808
ATPase family AAA domain-containing protein 55005
Ataxin-25005
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
ATP-dependent phosphofructokinase5005
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
GLS protein3003
beta-2 adrenergic receptor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0304
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Carbonic anhydrase 10406
Carbonic anhydrase 20507
Integrin beta-30011
Integrin alpha-IIb0011
ATP-citrate synthase 0101
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0214
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, NMDA 2A 0214
Glutamate receptor ionotropic, NMDA 2B0214
Glutamate receptor ionotropic, NMDA 2C0214
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0214
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0214
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0214
Carbonic anhydrase 0101
Hsf1 protein0011
G3003
Carbonic anhydrase 0101
cytochrome P450 2C9 precursor1001
Solute carrier family 22 member 60202
Carbonic anhydrase 120203
HLA class I histocompatibility antigen, B alpha chain 3003
Albumin0202
Carbonic anhydrase 30203
Carbonic anhydrase 40203
Carbonic anhydrase 60203
Delta-type opioid receptor0101
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Carbonic anhydrase 5A, mitochondrial0203
Carbonic anhydrase 70203
Histamine H2 receptor1001
Cytochrome P450 2J20101
Spike glycoprotein5005
Guanine nucleotide-binding protein G2002
Mu-type opioid receptor0101
Carbonic anhydrase 90203
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Inositol hexakisphosphate kinase 13003
Carbonic anhydrase 130202
Carbonic anhydrase 140203
Carbonic anhydrase 5B, mitochondrial0203
cytochrome P450 2C9, partial3003
SMAD family member 22002
SMAD family member 32002
aryl hydrocarbon receptor4004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
DNA polymerase iota isoform a (long)4004
DNA repair protein RAD52 homolog isoform a0002
Tyrosine-protein kinase ABL10123
Cytochrome P450 2C80001
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0022
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50102
DNA polymerase beta2002
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
Adenosine receptor A2a0202
7,8-dihydro-8-oxoguanine triphosphatase0101
Toll-like receptor 80011
Toll-like receptor 70011
Chain A, Ferritin light chain4004
Chain A, Cruzipain2002
Parkin2002
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
Caspase-72002
caspase-32002
serine/threonine-protein kinase PLK11001
DNA polymerase eta isoform 12002
Ornithine decarboxylase0002
Retinoic acid receptor alpha0224
Retinoic acid receptor gamma0224
Retinoic acid receptor beta0224
Cellular retinoic acid-binding protein 20022
Mitogen-activated protein kinase 10213
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10203
Cellular retinoic acid-binding protein 10022
Mitogen-activated protein kinase 140112
Rap guanine nucleotide exchange factor 41001
Olfactory receptor 51E20101
Solute carrier organic anion transporter family member 2A10101
HLA class I histocompatibility antigen, A alpha chain 0101
5-hydroxytryptamine receptor 2C0101
5-hydroxytryptamine receptor 2A0101
5-hydroxytryptamine receptor 2B0101
Gastrin/cholecystokinin type B receptor0101
Melanocortin receptor 40213
Melanocortin receptor 50112
Melanocortin receptor 30011
Melanocortin receptor 50011
Melanocortin receptor 30213
Urotensin-2 receptor0011
Melanocortin receptor 40011
Melanocyte-stimulating hormone receptor0213
Melanocyte-stimulating hormone receptor0011
Chain E, Fibrin beta chain0101
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
Fumarate hydratase1001
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase3003
caspase 7, apoptosis-related cysteine protease1001
hypothetical protein, conserved1001
isocitrate dehydrogenase 1, partial1001
polyprotein1001
luciferase1001
caspase-31001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
caspase-9 isoform alpha precursor0101
histone deacetylase 9 isoform 31001
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
neuropeptide S receptor isoform A1001
Glutathione reductase0101
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Amine oxidase [flavin-containing] A0101
Alpha-1D adrenergic receptor0303
Cruzipain0101
Inositol monophosphatase 11001
TAR DNA-binding protein 431001
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
Chain A, AKAP9-BRAF fusion protein0101
tyrosine-protein kinase Yes1001
Bone morphogenetic protein receptor type-1B0011
Membrane-associated progesterone receptor component 10011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pirin0101
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
GTPase KRas0101
RAF proto-oncogene serine/threonine-protein kinase0113
High affinity nerve growth factor receptor0011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Cyclin-dependent kinase 10011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0112
Glycogen phosphorylase, brain form0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0124
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Cyclin-dependent kinase 20011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Serine/threonine-protein kinase B-raf 0101
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
DNA replication licensing factor MCM40011
Myosin-100011
Vascular endothelial growth factor receptor 20101
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30011
Dual specificity mitogen-activated protein kinase kinase 40011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10012
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
Heat shock factor protein 10101
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10112
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Aspartyl/asparaginyl beta-hydroxylase0101
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Serine/threonine-protein kinase ATR0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Cyclin-dependent kinase 100011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Serine/threonine-protein kinase Nek10011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Phenylalanine--tRNA ligase beta subunit0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200112
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20012
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Long-chain-fatty-acid--CoA ligase 50011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase 38-like0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
Glucocorticoid receptor0213
Glycine receptor subunit alpha-10202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
NFKB1 protein, partial1001
cytochrome P450 2C19 precursor1001
muscarinic acetylcholine receptor M11001
Histamine H4 receptor0101
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20103
5'-AMP-activated protein kinase subunit beta-20001
Bile salt export pump0101
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Cystathionine gamma-lyase0101
Prostaglandin G/H synthase 20101
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 80102
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150102
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit beta-10001
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0112
Substance-P receptor0213
Neuromedin-K receptor0112
Substance-P receptor0101
Substance-K receptor0101
D(2) dopamine receptor0011
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Mas-related G-protein coupled receptor member X20011
Nuclear receptor subfamily 1 group I member 20011
UDP-glucuronosyltransferase 2B70001
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
72 kDa type IV collagenase0101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Neutrophil collagenase0101
Collagenase 30101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
P2Y purinoceptor 120101
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Solute carrier family 22 member 70001
Chain A, Nuclear Receptor ROR-beta0101
thyrotropin-releasing hormone receptor1001
cytochrome P450 3A4 isoform 11001
M-phase phosphoprotein 81001
Gamma-aminobutyric acid receptor subunit pi1001
Cytochrome P450 1A20011
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor gamma 0227
Gamma-aminobutyric acid receptor subunit beta-11001
Alpha-1A adrenergic receptor0101
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Retinoic acid receptor RXR-alpha0224
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Retinoic acid receptor RXR-beta0224
Indoleamine 2,3-dioxygenase 10101
Gamma-aminobutyric acid receptor subunit alpha-61001
Cytochrome P450 2C190011
Nuclear receptor ROR-alpha0101
Retinoic acid receptor RXR-gamma0224
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Indoleamine 2,3-dioxygenase 20101
GABA theta subunit1001
Nuclear receptor ROR-beta0101
Gamma-aminobutyric acid receptor subunit epsilon1001
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Plasma kallikrein0001
Adenosine receptor A10001
Adenosine receptor A2a0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10202
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Chain A, Arginase 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]