Page last updated: 2024-08-05 13:03:43
peptide antibiotic
A chemically diverse class of peptides that exhibit antimicrobial properties.
ChEBI ID: 25903
Members (8)
Member | Definition | Role |
---|---|---|
aglucovancomycin b | A peptide antibiotic that is vancomycin lacking the disaccharide moiety. | vancomycin aglycone zwitterion; vancomycin aglycone |
althiomycin | A peptide antibiotic isolated from soil and enteric bacteria. It is a protein synthesis inhibitor which exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria. | althiomycin |
complestatin | A heterodetic cyclic peptide consisting of N-acylated trytophan, 3,5-dichloro-4-hydroxyphenylglycine, 4-hydroxyphenylglycine, 3,5-dichloro-4-hydroxyphenylglycyl, tyrosine and 4-hydroxyphenylglycine residues joined in sequence and in which the side-chain of the central 4-hydroxyphenylglycine residue is attached to the side-chain of the tryptophan via a C3-C6 bond and to the side-chain of the tyrosine via an ether bond from C5. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity. | chloropeptin II; isocomplestatin |
lugdunin | A thiazolidine-containing homodetic cyclic peptide that is isolated from human nasal bacteria. Exhibits bactericidal activity against many major pathogens including methicillin-resistant Staphylococcus aureus (MRSA). | lugdunin |
teixobactin | A cyclodepsipeptide that is isolated from the previously unculturable bacterial species Eleftheria terrae and is active against gram-positive bacteria. | teixobactin |
tyrocidine | A homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Phe, D-Phe, L-Asn, L-Gln, L-Tyr, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail. | tyrocidine A |
viomycin | A cyclic peptide antibiotic produced by the actinomycete Streptomyces puniceus, used in the treatment of tuberculosis. | viomycin |
zwittermicin a | The (+)-enantiomer of zwittermicin A. It is a water-soluble natural antibiotic from the fermentation of the soil-borne bacterium Bacillus cereus and shows significant activity against phytopathogenic fungi. | (+)-zwittermicin A |
Research
Studies (915)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 655 (71.58) | 18.7374 |
1990's | 40 (4.37) | 18.2507 |
2000's | 81 (8.85) | 29.6817 |
2010's | 112 (12.24) | 24.3611 |
2020's | 27 (2.95) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 8 (0.82%) | 5.53% |
Reviews | 42 (4.29%) | 6.00% |
Case Studies | 3 (0.31%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 925 (94.58%) | 84.16% |