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ChEBI ID: 49302
| Member | Definition | Role |
|---|---|---|
| 2-hydroxybutyric acid | A hydroxybutyric acid having a single hydroxyl group located at position 2; urinary secretion of 2-hydroxybutyric acid is increased with alcohol ingestion or vigorous physical exercise and is associated with lactic acidosis and ketoacidosis in humans and diabetes in animals. | 2-hydroxybutyric acid |
| 2-hydroxyisobutyric acid | A 2-hydroxy monocarboxylic acid that is isobutyric acid bearing a hydroxy substituent at position 2. It is a metabolite of methyl tertiary-butyl ether. | 2-hydroxyisobutyric acid |
| 2-hydroxyisovaleric acid | A valine derivative that is valine in which the amino group has been replaced by a hydroxy group. | 2-hydroxy-3-methylbutyric acid |
| 3-chlorolactate | A 2-hydroxy monocarboxylic acid that is lactic acid in which one of the methyl hydrogens is replaced by a chloro group. | 3-chlorolactic acid |
| 3-dehydroquinic acid | A 4-oxo monocarboxylic acid derived from quinic acid by oxidation of the hydroxy group at position 3 to the corresponding keto group. | 3-dehydroquinic acid |
| 3-hydroxymandelic acid | A 2-hydroxy monocarboxylic acid that is mandelic acid substituted by a hydroxy group at position 3'. | 3-hydroxymandelic acid |
| 3-phenyllactic acid | A 2-hydroxy monocarboxylic acid that is lactic acid in which one of the methyl hydrogens is substituted by a phenyl group. | 3-phenyllactic acid |
| 3,4-dihydroxymandelic acid | A catechol that is the 3,4-dihydroxy derivative of mandelic acid; a metabolite of L-dopa. | 3,4-dihydroxymandelic acid |
| 3,4-dihydroxyphenyllactic acid | 3-(3,4-dihydroxyphenyl)lactic acid | |
| atrolactic acid | atrolactic acid | |
| glycolic acid | A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated. | glycolic acid |
| lactic acid | A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group. | 2-hydroxypropanoic acid |
| mandelic acid | A 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups. | mandelic acid |
| tartronate semialdehyde | 2-hydroxy-3-oxopropanoic acid | |
| vanilmandelic acid | An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid. | vanillylmandelic acid |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6,731 (14.01) | 18.7374 |
| 1990's | 7,318 (15.23) | 18.2507 |
| 2000's | 12,467 (25.95) | 29.6817 |
| 2010's | 17,012 (35.41) | 24.3611 |
| 2020's | 4,509 (9.39) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 3,529 (6.98%) | 5.53% |
| Reviews | 2,253 (4.46%) | 6.00% |
| Case Studies | 1,190 (2.35%) | 4.05% |
| Observational | 419 (0.83%) | 0.25% |
| Other | 43,170 (85.38%) | 84.16% |