Page last updated: 2024-08-05 14:43:40

insect repellent

An insecticide that acts as a repellent to insects.

ChEBI ID: 71692

Members (8)

MemberDefinitionClass
2-pentylfuranA member of the class of furans that is furan in which the hydrogen at position 2 is replaced by a pentyl group. It is found in many heat-processed foods and drinks.2-pentylfuran
4-anisaldehydeA member of the class of benzaldehydes consisting of benzaldehyde itself carrying a methoxy substituent at position 4.p-methoxybenzaldehyde
cuminolA member of the class of benzyl alcohols in which the hydrogen at position 4 on the phenyl ring of benzyl alcohol has been replaced by an isopropyl group.4-isopropylbenzyl alcohol
deetA monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.N,N-diethyl-m-toluamide
nootkatoneA sesquiterpenoid that is 4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one which is substituted by methyl groups at positions 4 and 4a, and by an isopropenyl group at position 6 (the 4R,4aS,6R stereoisomer).(+)-nootkatone
piperonalAn arenecarbaldehyde that is 1,3-benzodioxole substituted by a formyl substituent at position 5. It has been isolated from Piper nigrum.piperonal
terpinoleneA p-menthadiene with double bonds at positions 1 and 4(8).terpinolene
thiamine hydrochlorideA hydrochloride obtained by combining thiamine chloride with one molar equivalent of hydrochloric acid.thiamine hydrochloride

Research

Studies (1,261)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990129 (10.23)18.7374
1990's155 (12.29)18.2507
2000's362 (28.71)29.6817
2010's419 (33.23)24.3611
2020's196 (15.54)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials31 (2.29%)5.53%
Reviews74 (5.48%)6.00%
Case Studies31 (2.29%)4.05%
Observational0 (0.00%)0.25%
Other1,215 (89.93%)84.16%

Protein Targets (49)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency19.622212
activating transcription factor 6Homo sapiens (human)Potency32.212913
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency11.034412
AR proteinHomo sapiens (human)Potency25.488389
aryl hydrocarbon receptorHomo sapiens (human)Potency60.509411
Cellular tumor antigen p53Homo sapiens (human)Potency47.852525
Chain A, Beta-lactamaseEscherichia coli K-12Potency7.943311
Chain A, Ferritin light chainEquus caballus (horse)Potency15.848911
Chain A, HADH2 proteinHomo sapiens (human)Potency39.810711
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency2.407213
Chain B, HADH2 proteinHomo sapiens (human)Potency39.810711
chromobox protein homolog 1Homo sapiens (human)Potency89.125113
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency21.510413
estrogen nuclear receptor alphaHomo sapiens (human)Potency39.7390814
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency21.608423
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency26.803744
farnesoid X nuclear receptorHomo sapiens (human)Potency54.390311
gemininHomo sapiens (human)Potency0.157223
GLI family zinc finger 3Homo sapiens (human)Potency25.559926
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency31.918711
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency53.763211
heat shock protein beta-1Homo sapiens (human)Potency35.813311
histone acetyltransferase KAT2A isoform 1Homo sapiens (human)Potency8.912511
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency19.944022
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency37.595637
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency1.122011
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency18.224812
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency39.283122
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency44.597412
pregnane X nuclear receptorHomo sapiens (human)Potency38.167825
progesterone receptorHomo sapiens (human)Potency24.355622
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency32.848523
retinoid X nuclear receptor alphaHomo sapiens (human)Potency12.154625
TAR DNA-binding protein 43Homo sapiens (human)Potency35.481311
thioredoxin glutathione reductaseSchistosoma mansoniPotency50.118711
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency39.446835
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency8.895412
thyroid stimulating hormone receptorHomo sapiens (human)Potency0.006911
USP1 protein, partialHomo sapiens (human)Potency39.810711
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency53.763211
VprHuman immunodeficiency virus 1Potency28.183811

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
4-aminobutyrate aminotransferase, mitochondrialHomo sapiens (human)IC501,000.000011
Cytochrome P450 1A2Homo sapiens (human)IC50270.000011
Cytochrome P450 2A5Mus musculus (house mouse)IC505.230011
Cytochrome P450 2A6Homo sapiens (human)IC505.150011
Succinate-semialdehyde dehydrogenase, mitochondrialHomo sapiens (human)IC501,000.000011
TyrosinaseHomo sapiens (human)IC50320.000011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Chain A, Odorant binding proteinAnopheles gambiae (African malaria mosquito)Kd31.300011
Chain B, Odorant binding proteinAnopheles gambiae (African malaria mosquito)Kd31.300011