Any compound used to suppress premature labour and immature birth by suppressing uterine contractions.
ChEBI ID: 66993
| Member | Definition | Class |
|---|---|---|
| bambuterol | A carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline. | bambuterol |
| berotek | A member of the class resorcinols that is 5-(1-hydroxyethyl)benzene-1,3-diol in which one of the methyl hydrogens is replaced by a 1-(4-hydroxyphenyl)propan-2-amino group. A beta2-adrenergic agonist, it is used (as the hydrobromide salt) as a bronchodilator in the management of reversible airway obstruction. | fenoterol |
| magnesium sulfate | A magnesium salt having sulfate as the counterion. | magnesium sulfate |
| nifedipine | nifedipine | |
| nitroglycerin | A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain. | nitroglycerin |
| sulindac | A monocarboxylic acid that is 1-benzylidene-1H-indene which is substituted at positions 2, 3, and 5 by methyl, carboxymethyl, and fluorine respectively, and in which the phenyl group of the benzylidene moiety is substituted at the para position by a methylsulfinyl group. It is a prodrug for the corresponding sulfide, a non-steroidal anti-inflammatory drug, used particularly in the treatment of acute and chronic inflammatory conditions. | sulindac |
| terbutaline | A member of the class of phenylethanolamines that is catechol substituted at position 5 by a 2-(tert-butylamino)-1-hydroxyethyl group. | terbutaline |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 14,772 (39.60) | 18.7374 |
| 1990's | 10,215 (27.38) | 18.2507 |
| 2000's | 6,771 (18.15) | 29.6817 |
| 2010's | 4,426 (11.86) | 24.3611 |
| 2020's | 1,121 (3.00) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 7,224 (17.73%) | 5.53% |
| Reviews | 2,582 (6.34%) | 6.00% |
| Case Studies | 2,735 (6.71%) | 4.05% |
| Observational | 75 (0.18%) | 0.25% |
| Other | 28,136 (69.04%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 18.4176 | 1 | 3 |
| 67.9K protein | Vaccinia virus | Potency | 13.1335 | 2 | 6 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 21.3138 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 20.6532 | 1 | 9 |
| AR protein | Homo sapiens (human) | Potency | 48.0332 | 9 | 11 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 15.1437 | 2 | 8 |
| arylsulfatase A | Homo sapiens (human) | Potency | 32.3938 | 1 | 2 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 12.2892 | 3 | 3 |
| Ataxin-2 | Homo sapiens (human) | Potency | 16.4661 | 2 | 2 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 0.4406 | 1 | 4 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 24.0084 | 2 | 2 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 13.0918 | 1 | 1 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 14.7704 | 2 | 3 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 1.9906 | 2 | 4 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 10.6928 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 51.0755 | 1 | 2 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 21.9621 | 1 | 7 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 2.6834 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 19.8162 | 2 | 6 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 1.1220 | 1 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 12.7415 | 1 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 39.3099 | 1 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 19.8162 | 2 | 6 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 43.4452 | 2 | 4 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 9.1453 | 1 | 4 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 20.0203 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 16.2190 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 38.9018 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.9836 | 2 | 10 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 23.8054 | 1 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 47.6313 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 17.1078 | 2 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 29.4335 | 8 | 14 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 37.5944 | 4 | 6 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 14.9999 | 1 | 8 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 10.6928 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 19.9418 | 3 | 3 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 16.2190 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.9836 | 1 | 5 |
| geminin | Homo sapiens (human) | Potency | 17.3039 | 3 | 11 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 26.4436 | 3 | 6 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 9.2600 | 1 | 2 |
| GLS protein | Homo sapiens (human) | Potency | 15.1202 | 1 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 29.7322 | 3 | 4 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 17.2465 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 7.0795 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 58.4789 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 49.0441 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 18.1985 | 2 | 11 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 44.9647 | 1 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 16.2190 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 16.7058 | 2 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 51.9973 | 1 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 0.6675 | 2 | 6 |
| IDH1 | Homo sapiens (human) | Potency | 5.1735 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 16.2190 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 10.4510 | 1 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 16.2190 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 7.8383 | 1 | 3 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 39.9800 | 1 | 1 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 38.7482 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 14.0759 | 2 | 14 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 21.6565 | 2 | 3 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 34.7650 | 1 | 3 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 11.2202 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 63.0957 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 48.5236 | 4 | 5 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 38.9571 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 66.8242 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 18.1101 | 2 | 11 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 39.0413 | 3 | 8 |
| Parkin | Homo sapiens (human) | Potency | 20.7328 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 18.1056 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 80.3039 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 36.5363 | 3 | 3 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 34.0421 | 4 | 6 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 37.2746 | 2 | 7 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 1.2589 | 1 | 1 |
| polyprotein | Zika virus | Potency | 35.4813 | 1 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 27.0050 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 10.0000 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 38.9620 | 2 | 2 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 70.7946 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 24.0357 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 40.3464 | 2 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 27.0728 | 1 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 40.8347 | 3 | 4 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 40.0255 | 3 | 5 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 16.4816 | 1 | 1 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 17.3396 | 1 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 24.3456 | 2 | 4 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 24.3456 | 2 | 4 |
| Smad3 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 39.8107 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 17.9199 | 1 | 3 |
| TDP1 protein | Homo sapiens (human) | Potency | 15.0265 | 2 | 15 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 26.9749 | 3 | 7 |
| Thrombopoietin | Homo sapiens (human) | Potency | 1.5849 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 27.8707 | 2 | 4 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 42.5913 | 3 | 4 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 10.5909 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 1.2589 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 1.2589 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 28.2956 | 2 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 28.8828 | 2 | 2 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 47.4991 | 3 | 4 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 12.9282 | 5 | 25 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 17.2465 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 8.3760 | 2 | 2 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | Rattus norvegicus (Norway rat) | IC50 | 1.1200 | 1 | 1 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | Rattus norvegicus (Norway rat) | IC50 | 1.1200 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.0010 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 18.2730 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 9.5720 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 18.2730 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 9.5720 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 100.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 25.0000 | 4 | 4 |
| Acetylcholinesterase | Rattus norvegicus (Norway rat) | IC50 | 30.0000 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | IC50 | 7.7010 | 1 | 1 |
| Adenosine receptor A1 | Homo sapiens (human) | Ki | 4.4920 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 96.1333 | 3 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 14.1000 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 7.2140 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 7.6645 | 3 | 4 |
| Albumin | Homo sapiens (human) | Ki | 26,302,700,000.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | IC50 | 0.2930 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 2.6900 | 1 | 1 |
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | IC50 | 2.6900 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 7.2140 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.0780 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 7.2140 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 4.0780 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 3 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 292.5000 | 2 | 2 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.0600 | 1 | 1 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Ki | 0.1260 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 182.5491 | 5 | 11 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 66.4500 | 1 | 2 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 50.5000 | 1 | 1 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | IC50 | 2.1910 | 1 | 1 |
| C-C chemokine receptor type 2 | Homo sapiens (human) | Ki | 0.8470 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 2 |
| Carboxylic ester hydrolase | Rattus norvegicus (Norway rat) | IC50 | 0.0030 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 0.1193 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 0.0033 | 4 | 4 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 3.0600 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 3.0600 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 28.4947 | 2 | 2 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 23.4000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | Ki | 17.4000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Mus musculus (house mouse) | IC50 | 46.0000 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 2 | Mus musculus (house mouse) | IC50 | 1.5000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 108.4500 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 94.2000 | 1 | 3 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | IC50 | 2.0200 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 9.6190 | 1 | 1 |
| perilipin-5 | Homo sapiens (human) | IC50 | 7.1330 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 15.1010 | 1 | 1 |
| Potassium channel subfamily K member 2 | Bos taurus (cattle) | IC50 | 8.2000 | 1 | 1 |
| Potassium voltage-gated channel subfamily A member 1 | Homo sapiens (human) | IC50 | 96.0000 | 1 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | IC50 | 6.1000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 125.9125 | 6 | 6 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 16.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 8.8000 | 1 | 1 |
| Retinoic acid receptor RXR-alpha | Homo sapiens (human) | IC50 | 82.9000 | 1 | 1 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 37.0000 | 1 | 1 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 18.5940 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 0.0429 | 3 | 9 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 3.6995 | 6 | 6 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 0.0385 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | Ki | 0.0102 | 2 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | Ki | 0.0038 | 2 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | Ki | 0.0039 | 2 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 5.8550 | 4 | 4 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | Ki | 0.0147 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 7.3567 | 3 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | Ki | 0.0147 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 7.3567 | 3 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Mus musculus (house mouse) | IC50 | 1.2000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | Ki | 0.0147 | 1 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | Ki | 0.0038 | 2 | 4 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Beta-1 adrenergic receptor | Homo sapiens (human) | Kd | 101.3852 | 1 | 4 |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | EC50 | 0.0185 | 2 | 2 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | EC50 | 3.1623 | 1 | 1 |
| Beta-2 adrenergic receptor | Homo sapiens (human) | Kd | 51.3502 | 4 | 8 |
| Beta-2 adrenergic receptor | Bos taurus (cattle) | Kd | 3.9800 | 1 | 1 |
| Beta-3 adrenergic receptor | Homo sapiens (human) | Kd | 101.3853 | 1 | 4 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 7.4000 | 1 | 1 |
| Complement C5 | Homo sapiens (human) | Kd | 0.5700 | 1 | 1 |
| Glycine receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 0.3800 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | EC50 | 22.6500 | 1 | 1 |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | Kd | 100.0000 | 1 | 1 |
| Potassium channel subfamily K member 2 | Homo sapiens (human) | EC50 | 8.1800 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Mus musculus (house mouse) | EC50 | 0.4000 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | ID50 | 0.0100 | 1 | 1 |
| Beta-2 adrenergic receptor | Bos taurus (cattle) | Concentration | 1,000,000.0000 | 1 | 1 |
| Beta-2 adrenergic receptor | Bos taurus (cattle) | KD app | 4.4800 | 1 | 1 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | ID50 | 0.0100 | 1 | 1 |
| Leukotriene B4 receptor 2 | Homo sapiens (human) | ID50 | 0.0100 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | ID50 | 700,000.0050 | 2 | 2 |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | ID50 | 700,000.0050 | 2 | 2 |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | ID50 | 700,000.0050 | 2 | 2 |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | ID50 | 700,000.0050 | 2 | 2 |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | ID50 | 700,000.0050 | 2 | 2 |
| Phospholipase A2, membrane associated | Homo sapiens (human) | ID50 | 0.0100 | 1 | 1 |
| Platelet-activating factor receptor | Homo sapiens (human) | ID50 | 0.0100 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | ID50 | 0.0100 | 1 | 2 |