A racemate is an equimolar mixture of a pair of enantiomers.
| Member | Definition | Role |
|---|
| 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine | A racemate comprising equimolar amounts of (R)- and (S)-crizotinib. The active (R)-enantiomer acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer. | 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine; rac-crizotinib |
| bupivacaine hydrochloride | A racemate composed of equimolar amounts of dextrobupivacaine hydrochloride and levobupivacaine hydrochloride. The monohydrate form is commonly used as a local anaesthetic. | 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide hydrochloride; bupivacaine hydrochloride (anhydrous) |
| donepezil | A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. | 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one; donepezil |
| kavain | | DL-kavain |
| ketorolac | A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure. | 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid; ketorolac |
| laudanine | A racemate composed of equimolar amounts of (R)- and (S)-laudanosoline | laudanine; rac-laudanosoline |
| monastrol | A racemate comprising equimolar amounts of R- and S-monastrol. | ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; monastrol |
| oxybutynin | A racemate comprising equimolar amounts of (R)-oxybutynin and esoxybutynin. An antispasmodic used for the treatment of overactive bladder. | 4-(diethylamino)but-2-yn-1-ol; oxybutynin |
| pirmenol | | pirmenol |
| proglumide | A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs. | N(2)-benzoyl-N,N-dipropyl-alpha-glutamine; proglumide |
| tetrindole | A racemate composed of equimolar amounts of (R)- and (S)-tetrindole hydrochloride. | tetrindole hydrochloride |
| tosufloxacin, 4-toluene sulfonate | A racemate comprising equimolar amounts of (R)- and (S)-tosufloxacin tosylate. | tosufloxacin tosylate |