Congenital Infection, Toxoplasma gondii

Synonym
Toxoplasma Infections, Congenital
Congenital Toxoplasmosis
Toxoplasmosis, Fetal
Congenital Infection, Toxoplasma gondii
Congenital Toxoplasma Infections
Toxoplasmosis, Prenatal
Congenital Toxoplasma gondii Infection

Excerpt	Reference
"Preventing congenital toxoplasmosis is fundamental, and in France screening tests for primary infection are obligatory for pregnant women."	( Aissi, E; Ajana, F; Camus, D; Fortier, B; Pinto de Sousa, MI, 1991)
"Prevention of congenital toxoplasmosis is obtained by educating pregnant women at risk about how to prevent the infection and by diagnosing acute infection of mother."	( Galanti, B; Russo, M, 1990)
"Congenital toxoplasmosis is still one of the most frequent causes of fetal death."	( Couvreur, J; Derouin, F; Jacqz-Aigrain, E; Leport, C; Thulliez, P, 2000)
"Congenital toxoplasmosis is a potentially serious infection which usually affects infants born to non immune women."	( Baudon, JJ; Ducrocq, S; Gold, F; Lebas, F; Mégier, P; Mucignat, V; Paris, L, 2004)
"Congenital toxoplasmosis is considered a rare but potentially severe infection."	( Basevi, V; D'Amico, R; Di Mario, S; Gagliotti, C; Gori, G; Magrini, N; Spettoli, D, 2009)
"Congenital toxoplasmosis is caused by transplacental contamination of the fetus withToxoplasma gondiifollowing maternal primary infection."	( Dumon, H; Franck, J; Garcia-Méric, P; Piarroux, R, 2010)
"Congenital toxoplasmosis is considered a rare but potentially severe infection."	( Basevi, V; D'Amico, R; Di Mario, S; Gagliotti, C; Gori, G; Magrini, N; Spettoli, D, 2013)
"Question Congenital toxoplasmosis is a dangerous fetal infection."	( Chaudhry, SA; Gad, N; Koren, G, 2014)
"Congenital toxoplasmosis is considered a rare but potentially severe infection."	( Basevi, V; D'Amico, R; Di Mario, S; Gagliotti, C; Gori, G; Magrini, N; Spettoli, D, 2015)
"Congenital toxoplasmosis is caused by in utero infection of the fetus with the intracellular parasite Toxoplasma gondii."	( Chorlton, SD, 2019)

Excerpt	Reference
"Most infants with congenital Toxoplasma gondii infection have no symptoms at birth, but many will have retinal disease or neurologic abnormalities later in life."	( Abroms, I; Eaton, RB; Guerina, NG; Hoff, R; Hsu, HW; Lynfield, R; Maguire, JH; Meissner, HC; Pasternack, MS; Stechenberg, B, 1994)
"Many children with congenital toxoplasmosis have substantial retinal damage at birth and consequent loss of vision."	( Boyer, KM; Holfels, E; Hopkins, J; Luciano, R; Mack, D; McLeod, R; Meier, P; Mets, MB; Patel, D; Remington, JS; Roizen, N; Stein, L; Stein, M; Swisher, CN; Withers, S, 1996)
"Many children with congenital toxoplasmosis have substantial retinal damage at birth and consequent loss of vision."	( Boyer, KM; Holfels, E; Hopkins, J; Luciano, R; Mack, D; McLeod, R; Meier, P; Mets, MB; Patel, D; Remington, JS; Roizen, N; Stein, L; Stein, M; Swisher, CN; Withers, S, 1997)
"Without treatment, congenital toxoplasmosis has recurrent, recrudescent, adverse outcomes."	( Boyer, K; Heydemann, P; Holfels, E; Jalbrzikowski, J; Karrison, T; Kasza, K; Latkany, P; McLeod, R; Meier, P; Mets, M; Noble, AG; Remington, J; Roizen, N; Swisher, C; Withers, S, 2006)

Excerpt	Reference
"In general, prenatal therapy of congenital toxoplasmosis is beneficial in reducing the frequency of infant infection."	( Georgiev, VS, 1994)
"Our current treatment strategy for congenital toxoplasmosis consists of a 24-month course of pyrimethamine-sulfadoxine (Fansidar) combined with folinic acid (Lederfoline)."	( Aubert, D; Bonhomme, A; Chemla, C; Dupouy, D; Guenounou, M; Leroux, B; Pinon, JM; Pluot, M; Quereux, C; Schmit, G; Talmud, M; Trenque, T; Villena, I, 1998)
"Pre- and neonatal screening for congenital toxoplasmosis rests upon the assumption that treatment is beneficial on either acute symptoms or in preventing later reactivation."	( Petersen, E; Schmidt, DR, 2003)
"The treatment of reference of congenital toxoplasmosis combines two folate synthesis inhibitors, pyrimethamine and an antibacterial sulfamide (sulfadiazine or sulfadoxine)."	( Coutty, N; Decocq, J; Delahousse, G; Detourmignies, L; Le Goueff, F; Mubiayi, N, 2004)
"Without treatment, congenital toxoplasmosis has recurrent, recrudescent, adverse outcomes."	( Boyer, K; Heydemann, P; Holfels, E; Jalbrzikowski, J; Karrison, T; Kasza, K; Latkany, P; McLeod, R; Meier, P; Mets, M; Noble, AG; Remington, J; Roizen, N; Swisher, C; Withers, S, 2006)
"Curative treatment of congenital toxoplasmosis is based on the association of pyrimethamine and sulfonamide."	( de Montgolfier, I; Freihuber, C; Genuini, M; Girard, I; Kieffer, F; Mitanchez, D, 2011)
"Regular follow-up revealed congenital toxoplasmosis in both eyes, which was surgically treated, while neurofunctional assessment results were unremarkable."	( Huang, L; Li, J; Ma, D; Shi, J; Wen, Y; Yang, X; Zhao, J, 2021)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	136 (43.17)	23.3326
1990's	61 (19.37)	12.5806
2000's	54 (17.14)	18.1394
2010's	49 (15.56)	28.8240
2020's	15 (4.76)	9.53

Drug	Relationship Strength	Studies	Trials
formaldehyde	low	1	0
urea	low	1	0
cefuroxime	low	1	0
pentetic acid	low	1	0
furosemide	low	1	0
2-propanol	low	1	0
phenobarbital	low	1	0
pyrimethamine	medium	184	4
sulfadiazine	medium	93	3
sulfadimethoxine	low	1	0
sulfamerazine	low	1	0
sulfameter	low	1	0
sulfamethazine	low	3	0
sulfamethoxazole	low	1	0
sulfamethoxypyridazine	low	2	0
sulfanilamide	low	4	0
sulfisomidine	low	1	0
thalidomide	low	2	0
trimethoprim	low	2	0
prednisolone	low	1	0
thymidine	low	2	0
prednisone	low	5	0
lysine	low	1	0
edetic acid	low	1	0
methylene blue	low	7	0
cycloheximide	low	1	0
isoleucine	low	1	0
methylprednisolone	low	2	0
pyrazines	low	1	0
betamethasone	low	1	0
azomycin	low	1	0
erythromycin	low	2	0
pyrithioxin	low	1	0
sulfadoxine	medium	20	1
vidarabine	low	1	0
technetium	low	1	0
phenyl acetate	low	1	0
benzonidazole	low	1	0
4-methoxyamphetamine	low	1	0
propiconazole	low	2	0
fanasil, pyrimethamine drug combination	medium	14	1
delphinidin	low	1	0
buparvaquone	low	1	0
atovaquone	low	4	0
nicotine	low	1	0
nsc-172755	medium	1	1
atropine	low	2	0
cortisone	low	1	0
trimethoprim, sulfamethoxazole drug combination	medium	7	1
arachidonic acid	low	1	0
clindamycin	low	2	0
zithromax	low	4	0
mercaptopurine	low	1	0
curcumin	low	1	0
naphthoquinones	low	1	0
bilirubin	low	1	0
acetylspiramycin	low	1	0
morphine	low	1	0
deamino arginine vasopressin	low	2	0
dizocilpine maleate	low	1	0
neospiramycin	low	1	0
nifurtimox	low	1	0
gadolinium dtpa	low	1	0
indocyanine green	low	1	0
pituitrin	low	1	0
oligonucleotides	low	1	0
cellulose	low	1	0
ro13-9904	low	1	0
sodium ethylxanthate	low	1	0
piperidines	low	1	0
tetracycline	low	1	0
chlortetracycline	low	3	0
oxytetracycline, anhydrous	low	1	0
demeclocycline	low	2	0
exudates	low	2	0
acyclovir	low	2	0
levoleucovorin	medium	31	1
folic acid	low	5	0
ganciclovir	low	1	0
valganciclovir	low	1	0
eye	low	29	0
maltodextrin	low	1	0
concanavalin a	low	1	0

Protein Targets (812)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
RAR-related orphan receptor gamma	20	0	0	20
GLI family zinc finger 3	27	0	0	27
AR protein	30	0	0	30
aldehyde dehydrogenase 1 family, member A1	20	0	0	20
retinoic acid nuclear receptor alpha variant 1	17	0	0	17
retinoid X nuclear receptor alpha	19	0	0	19
estrogen nuclear receptor alpha	31	0	0	31
peroxisome proliferator-activated receptor delta	14	0	0	14
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	13	0	0	13
activating transcription factor 6	9	0	0	9
v-jun sarcoma virus 17 oncogene homolog (avian)	14	0	0	14
Histone H2A.x	12	0	0	12
thyroid hormone receptor beta isoform a	9	0	0	9
heat shock protein beta-1	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	23	0	0	23
lamin isoform A-delta10	15	0	0	15
Voltage-dependent calcium channel gamma-2 subunit	13	0	0	13
Glutamate receptor 2	13	0	0	13
5-hydroxytryptamine receptor 2C	0	2	1	3
5-hydroxytryptamine receptor 2A	0	4	1	5
5-hydroxytryptamine receptor 1A	0	1	1	2
5-hydroxytryptamine receptor 1B	0	1	1	2
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	3	1	4
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	0	1	1
Sodium-dependent serotonin transporter	0	2	0	2
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Ferritin light chain	5	0	0	5
Thymidine kinase	0	3	0	4
thioredoxin reductase	10	0	0	10
phosphopantetheinyl transferase	10	0	0	10
GLS protein	8	0	0	8
TDP1 protein	23	0	0	23
Smad3	7	0	0	7
thyroid stimulating hormone receptor	9	0	0	9
EWS/FLI fusion protein	12	0	0	13
arylsulfatase A	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	18	0	0	18
Bloom syndrome protein isoform 1	7	0	0	7
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Solute carrier family 22 member 1	0	4	0	7
ATP-binding cassette sub-family C member 3	0	15	0	15
Multidrug resistance-associated protein 4	0	15	0	16
Solute carrier family 22 member 6	0	1	0	2
Bile salt export pump	0	2	0	2
Bile salt export pump	0	26	0	26
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	2	0	6
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2C9	0	8	0	8
Cytochrome P450 2J2	0	6	0	6
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Purine nucleoside phosphorylase	0	0	3	3
Solute carrier family 22 member 6	0	0	0	2
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	2
Canalicular multispecific organic anion transporter 1	0	15	0	15
Thymidine kinase	0	1	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	9	0	0	9
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	14	0	0	14
Chain A, Beta-lactamase	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	9	0	0	9
Chain A, Cruzipain	4	0	0	4
15-lipoxygenase, partial	3	0	0	3
USP1 protein, partial	9	0	0	9
Microtubule-associated protein tau	9	0	0	9
thioredoxin glutathione reductase	7	0	0	7
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
cellular tumor antigen p53 isoform a	6	0	0	6
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	6	0	0	6
vitamin D3 receptor isoform VDRA	8	0	0	8
nuclear receptor ROR-gamma isoform 1	6	0	0	6
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
DNA polymerase kappa isoform 1	5	0	0	5
cytochrome P450 3A4 isoform 1	10	0	0	10
histone acetyltransferase KAT2A isoform 1	4	0	0	4
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
caspase-1 isoform alpha precursor	3	0	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	10	0	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15B	6	0	0	6
Prostaglandin G/H synthase 1	0	0	0	1
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Aromatase	0	1	0	1
Tissue factor	0	2	0	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	10	0	0	10
Gamma-aminobutyric acid receptor subunit delta	10	0	0	10
Gamma-aminobutyric acid receptor subunit gamma-2	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-5	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-3	10	0	0	10
Gamma-aminobutyric acid receptor subunit gamma-1	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-4	10	0	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	10	0	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	10	0	0	10
Prostaglandin G/H synthase 2	0	2	1	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Histamine H2 receptor	8	0	0	9
10 kDa heat shock protein, mitochondrial	0	4	0	4
Calmodulin	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	10	0	0	10
Gamma-aminobutyric acid receptor subunit beta-3	10	0	0	10
Gamma-aminobutyric acid receptor subunit beta-2	10	0	0	10
Prostaglandin G/H synthase 2	0	1	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	3	0	3
Lanosterol 14-alpha demethylase	0	2	0	2
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
GABA theta subunit	10	0	0	10
Gamma-aminobutyric acid receptor subunit epsilon	10	0	0	10
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	4	0	5
SMAD family member 2	5	0	0	5
SMAD family member 3	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	14	0	0	14
estrogen-related nuclear receptor alpha	22	0	0	22
pregnane X nuclear receptor	19	0	0	19
peroxisome proliferator activated receptor gamma	10	0	0	10
IDH1	10	0	0	10
aryl hydrocarbon receptor	11	0	0	11
Dihydroorotate dehydrogenase	0	1	0	1
cytochrome P450 2C9 precursor	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
transcriptional regulator ERG isoform 3	6	0	0	6
thyroid hormone receptor beta isoform 2	17	0	0	17
geminin	26	0	0	26
Vpr	2	0	0	2
peripheral myelin protein 22	7	0	0	7
Cytochrome b	0	1	0	1
Cellular tumor antigen p53	16	0	0	16
Integrin beta-3	4	0	0	4
Integrin alpha-IIb	4	0	0	4
Dihydroorotate dehydrogenase (fumarate)	0	1	0	1
Spike glycoprotein	7	0	1	8
Guanine nucleotide-binding protein G	4	0	0	4
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	2
TAR DNA-binding protein 43	8	0	0	8
Dihydroorotate dehydrogenase	0	2	0	2
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
nuclear receptor subfamily 1, group I, member 3	18	0	0	18
glucocorticoid receptor [Homo sapiens]	17	0	0	17
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	5	0	0	5
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	2	0	2
Muscarinic acetylcholine receptor M2	0	3	1	7
Muscarinic acetylcholine receptor M4	0	2	1	5
Muscarinic acetylcholine receptor M1	0	4	1	7
Muscarinic acetylcholine receptor M3	0	4	1	7
Muscarinic acetylcholine receptor M4	0	5	1	8
Muscarinic acetylcholine receptor M5	0	4	1	7
Muscarinic acetylcholine receptor M5	0	2	1	5
Muscarinic acetylcholine receptor M2	0	4	1	8
Muscarinic acetylcholine receptor M1	0	2	1	6
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M3	0	2	1	5
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 7	0	3	0	3
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	2
Glyceraldehyde-3-phosphate dehydrogenase	0	1	0	1
Cytochrome P450 1A2	0	2	0	2
Cytochrome P450 3A4	0	6	1	7
Cytochrome P450 2D6	0	1	0	1
Cytochrome P450 2C19	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	6	0	6
Aurora kinase B	0	1	0	1
pregnane X receptor	7	0	0	7
progesterone receptor	14	0	0	14
farnesoid X nuclear receptor	13	0	0	13
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	8	0	0	8
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
ORF73	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Caspase-7	2	0	0	2
Inositol monophosphatase 1	3	0	0	3
Fumarate hydratase	8	0	0	8
estrogen receptor 2 (ER beta)	11	0	0	11
G	4	0	0	4
polyprotein	8	0	0	8
Interferon beta	8	0	0	8
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
M-phase inducer phosphatase 2	0	1	0	1
Inositol hexakisphosphate kinase 1	4	0	0	4
cytochrome P450 2C9, partial	4	0	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	9	0	9
endonuclease IV	4	0	0	4
dopamine D1 receptor	3	0	0	3
regulator of G-protein signaling 4	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
peripheral myelin protein 22 isoform 1	2	0	0	2
chromobox protein homolog 1	12	0	0	12
flap endonuclease 1	6	0	0	6
survival motor neuron protein isoform d	8	0	0	8
M-phase phosphoprotein 8	3	0	0	3
muscarinic acetylcholine receptor M1	2	0	0	2
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	3	0	3
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
Luciferase	5	0	0	5
interleukin 8	7	0	0	7
acetylcholinesterase	6	0	0	6
Nrf2	1	0	0	1
ATAD5 protein, partial	4	0	0	4
alkaline phosphatase, intestinal	0	1	0	1
apical membrane antigen 1, AMA1	3	0	0	3
caspase 7, apoptosis-related cysteine protease	3	0	0	3
PINK1	1	0	0	1
glucocerebrosidase	2	0	0	2
Parkin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
toll-like receptor 9	0	1	0	1
caspase-3	3	0	0	3
TPA: protein transporter TIM10	0	1	0	1
thyroid stimulating hormone receptor	6	0	0	6
thyrotropin-releasing hormone receptor	2	0	0	2
lysosomal alpha-glucosidase preproprotein	3	0	0	3
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
perilipin-5	0	1	0	1
intestinal alkaline phosphatase precursor	0	1	0	1
perilipin-1	0	1	0	1
huntingtin isoform 2	2	0	0	2
importin subunit beta-1 isoform 1	2	0	0	2
pyruvate kinase PKM isoform a	2	0	0	2
mitogen-activated protein kinase 1	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
snurportin-1	2	0	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	7	0	0	7
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
muscleblind-like protein 1 isoform 1	4	0	0	4
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
lethal factor (plasmid)	5	0	0	5
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
neuropeptide S receptor isoform A	2	0	0	2
Prostaglandin E synthase	0	1	0	1
Histone deacetylase 3	0	1	0	1
Acetylcholinesterase	0	2	0	2
Lysine-specific histone demethylase 1A	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Amyloid-beta precursor protein	0	3	0	4
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Cholinesterase	0	2	0	2
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	3
Replicase polyprotein 1ab	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Microtubule-associated protein tau	0	2	1	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tyrosinase	0	1	0	1
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Alpha-1B adrenergic receptor	0	3	0	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Acetylcholinesterase	0	2	0	2
Heme oxygenase 2	0	1	0	1
Alpha-1D adrenergic receptor	0	3	0	3
Amine oxidase [flavin-containing] B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Alpha-synuclein	4	3	1	8
Alpha-1A adrenergic receptor	0	3	0	3
Glycogen synthase kinase-3 beta	0	1	0	1
Nuclear receptor ROR-gamma	6	0	0	6
Histone deacetylase 4	0	1	0	1
Beta-secretase 1	0	1	0	1
Cholinesterase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	2	0	2
Serine/threonine-protein kinase PAK 1	0	1	0	1
Histone deacetylase 1	0	2	0	2
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	1	1
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	2	0	2
CREB-binding protein	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
ATPase family AAA domain-containing protein 5	9	0	0	9
Ataxin-2	9	0	0	9
Histone deacetylase 8	0	2	0	2
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
glp-1 receptor, partial	8	0	0	8
PPM1D protein	4	0	0	4
67.9K protein	4	0	0	4
P53	1	0	0	1
RPL19A	0	0	1	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
COUP transcription factor 2 isoform a	0	1	0	1
Transmembrane protease serine 2	0	0	1	1
Glucose transporter	0	1	0	1
Hexose transporter 1	0	1	0	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Eukaryotic initiation factor 4A-I	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	0	2
Peptidyl-prolyl cis-trans isomerase FKBP3	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP4	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP14	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	0	1	0	1
heat shock protein 90, putative	0	0	0	2
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Epidermal growth factor receptor	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
ATP-dependent phosphofructokinase	4	0	0	4
Glutamate receptor ionotropic, NMDA 1	0	1	0	2
Glutamate receptor ionotropic, NMDA 2A	0	1	0	2
Glutamate receptor ionotropic, NMDA 2B	0	1	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	1	0	2
Eyes absent homolog 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Motilin receptor	0	0	1	1
acid sphingomyelinase	2	0	0	2
low molecular weight phosphotyrosine protein phosphatase isoform c	0	2	0	2
serine/threonine-protein kinase PLK1	2	0	0	2
streptokinase A precursor	0	0	3	3
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
Albumin	0	1	2	3
ATP-dependent translocase ABCB1	0	3	0	3
ATP-dependent translocase ABCB1	0	3	0	3
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
Chitinase B	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Low molecular weight phosphotyrosine protein phosphatase	0	2	0	2
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
Cytochrome P450 1B1	0	1	0	1
50S ribosomal protein L36 2	0	3	1	4
Chain A, Dihydrofolate reductase	0	0	1	1
alpha-galactosidase	1	0	0	1
Thymidylate synthase	0	3	0	3
Thymidylate synthase	0	1	0	2
Dihydrofolate reductase	0	4	2	7
Aldo-keto reductase family 1 member B1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Carbonic anhydrase 12	0	2	0	4
Carbonic anhydrase 1	0	4	0	7
Carbonic anhydrase 2	0	4	1	8
Carbonic anhydrase 3	0	2	0	3
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Carbonic anhydrase 4	0	2	0	4
Carbonic anhydrase 6	0	4	0	6
Serum paraoxonase/arylesterase 1	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	3	0	6
Carbonic anhydrase 7	0	2	0	4
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Carbonic anhydrase 9	0	3	0	5
Carbonic anhydrase 13	0	2	0	4
G-protein coupled receptor 35	0	1	1	2
Carbonic anhydrase 14	0	2	0	4
Carbonic anhydrase 5B, mitochondrial	0	2	0	5
ClpP	1	0	0	1
NFKB1 protein, partial	2	0	0	2
Transitional endoplasmic reticulum ATPase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	3
Proton-coupled amino acid transporter 1	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Cationic amino acid transporter 3	0	1	0	1
cytochrome P450 2D6	5	0	0	5
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
hypothetical protein, conserved	1	0	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
caspase-9 isoform alpha precursor	0	1	0	1
histone deacetylase 9 isoform 3	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
DNA polymerase eta isoform 1	2	0	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Albumin	0	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Sodium-dependent noradrenaline transporter	0	0	1	1
Cruzipain	0	1	0	1
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
phosphoglycerate kinase	2	0	0	2
nonstructural protein 1	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Androgen receptor	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Alpha-2A adrenergic receptor	0	0	1	1
Translocator protein	0	1	1	2
Histidine decarboxylase	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Delta-type opioid receptor	0	3	0	4
Delta-type opioid receptor	0	4	1	6
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	4	1	8
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	4
UDP-glucuronosyltransferase 1A3	0	0	0	1
Delta-type opioid receptor	0	2	1	4
Kappa-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	1	4
Mu-type opioid receptor	0	2	1	5
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	5	0	5
Beta-2 adrenergic receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
D(1A) dopamine receptor	1	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	2	2	6
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	1	2	2	6
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	1	1	3
Trypanothione reductase	0	1	0	1
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
GALC protein	2	0	0	2
cytochrome P450 2C19 precursor	3	0	0	3
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Plasma kallikrein	0	0	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
Adenosine receptor A1	0	0	0	1
Adenosine receptor A2a	0	0	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 13	0	1	0	2
Monocarboxylate transporter 10	0	0	0	1
Carbonic anhydrase 15	0	1	0	2
Phospholipase A-2-activating protein	0	1	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	2	2
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
cytochrome P450 2D6 isoform 1	1	0	0	1
dual specificity protein phosphatase 3	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Dihydrofolate reductase	0	4	0	4
Dihydrofolate reductase	0	2	0	2
Estrogen receptor	0	0	1	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	5	0	6
Substance-K receptor	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dipeptidyl peptidase 4	0	3	0	3
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Trace amine-associated receptor 5	0	0	2	2
Estrogen receptor beta	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
Aurora kinase A	0	1	0	1
5-hydroxytryptamine receptor 6	0	2	0	2
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protease	0	1	1	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Protein argonaute-2	0	0	2	2
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Adenosylhomocysteinase	0	1	0	1
Adenosine deaminase	0	0	0	1
RNA-directed RNA polymerase	0	1	1	2
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Congenital Infection, Toxoplasma gondii

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (315)

Protein Targets (812)

Congenital Infection, Toxoplasma gondii

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (315)

Drugs Studied (96)

Protein Targets (812)