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monohydroxypyridine
A hydroxypyridine carrying a single hydroxy substituent.
ChEBI ID: 38182
Members (19)
| Member | Definition | Role |
|---|---|---|
| 2-amino-3-hydroxypyridine | 2-amino-3-hydroxypyridine | |
| 2-hydroxypyridine | A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2. | pyridin-2-ol |
| 2-methyl-3-hydroxypyridine-5-carboxylic acid | The 5-hydroxy-6-methyl derivative of nicotinic acid. | 5-hydroxy-6-methylpyridine-3-carboxylic acid |
| 3-hydroxypicolinic acid | A monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides. | 3-hydroxypicolinic acid |
| 3-hydroxypyridine | A monohydroxypyridine that is pyridine in which the hydrogen at position 3 has been replaced by a hydroxy group. It has been detected as a thermal degradation product from the smoke of the burning leaves of Salvia divinorum, a Mexican psychoactive plant. | 3-pyridinol |
| 4-deoxypyridoxine | A pyridine ring substituted with methyl groups at positions 2 and 4, a hydroxyl at position 3, and a hydroxymethyl group at position 5. | 4-deoxypyridoxine |
| 4-hydroxypyridine | A monohydroxypyridine that is pyridine in which the hydrogen at position 4 has been replaced by a hydroxy group. | 4-hydroxypyridine; 4-pyridone |
| 6-hydroxynicotine | 6-hydroxynicotine | |
| 6-hydroxynicotinic acid | A monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid. | 6-hydroxynicotinic acid |
| ilicicolin h | An aromatic ketone in which the ketone carbonyl group is attached to a (1R,2R,4aS,7S,8aR)-4,7-dimethyl-1-[(1E)-prop-1-en-1-yl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-2-yl group and a 4-hydroxy-5-(4-hydroxyphenyl)-2-oxo-1,2-dihydropyridin-3-yl group. Isolated from the from the "imperfect" fungus Cylindrocladium iliciola strain MFC-870. | ilicicolin H |
| piericidin a | A member of the class of monohydroxypyridines that acts as an irreversible mitochondrial Complex I inhibitor that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of NADH:ubiquinone oxidoreductase | piericidin A |
| pyridoxal | A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxal |
| pyridoxal phosphate | The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal. | pyridoxal 5'-phosphate |
| pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid | An arenesulfonic acid that is pyridoxal 5'-phosphate carrying an additional 2,4-disulfophenylazo substituent at position 6. | 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid |
| pyridoxamine | A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. | pyridoxamine |
| pyridoxamine phosphate | A vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine. | pyridoxamine 5'-phosphate |
| pyridoxic acid | A methylpyridine that is 2-methylpyridine substituted by a hydroxy group at C-3, a carboxy group at C-4, and a hydroxymethyl group at C-5. It is the catabolic product of vitamin B6 and is excreted in the urine. | 4-pyridoxic acid |
| pyridoxine | A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. | pyridoxine |
| pyrithione | A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent. | pyrithione |
Research
Studies (14,252)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8,002 (56.15) | 18.7374 |
| 1990's | 2,157 (15.13) | 18.2507 |
| 2000's | 1,992 (13.98) | 29.6817 |
| 2010's | 1,547 (10.85) | 24.3611 |
| 2020's | 554 (3.89) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 664 (3.71%) | 5.53% |
| Reviews | 1,113 (6.22%) | 6.00% |
| Case Studies | 760 (4.25%) | 4.05% |
| Observational | 10 (0.06%) | 0.25% |
| Other | 15,351 (85.77%) | 84.16% |