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monohydroxypyridine

A hydroxypyridine carrying a single hydroxy substituent.

ChEBI ID: 38182

Members (19)

MemberDefinitionRole
2-amino-3-hydroxypyridine2-amino-3-hydroxypyridine
2-hydroxypyridineA monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2.pyridin-2-ol
2-methyl-3-hydroxypyridine-5-carboxylic acidThe 5-hydroxy-6-methyl derivative of nicotinic acid.5-hydroxy-6-methylpyridine-3-carboxylic acid
3-hydroxypicolinic acidA monohydroxypyridine that is picolinic acid in which the hydrogen at position 3 is replaced by a hydroxy group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of oligonucleotides.3-hydroxypicolinic acid
3-hydroxypyridineA monohydroxypyridine that is pyridine in which the hydrogen at position 3 has been replaced by a hydroxy group. It has been detected as a thermal degradation product from the smoke of the burning leaves of Salvia divinorum, a Mexican psychoactive plant.3-pyridinol
4-deoxypyridoxineA pyridine ring substituted with methyl groups at positions 2 and 4, a hydroxyl at position 3, and a hydroxymethyl group at position 5.4-deoxypyridoxine
4-hydroxypyridineA monohydroxypyridine that is pyridine in which the hydrogen at position 4 has been replaced by a hydroxy group.4-hydroxypyridine; 4-pyridone
6-hydroxynicotine6-hydroxynicotine
6-hydroxynicotinic acidA monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid.6-hydroxynicotinic acid
ilicicolin hAn aromatic ketone in which the ketone carbonyl group is attached to a (1R,2R,4aS,7S,8aR)-4,7-dimethyl-1-[(1E)-prop-1-en-1-yl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-2-yl group and a 4-hydroxy-5-(4-hydroxyphenyl)-2-oxo-1,2-dihydropyridin-3-yl group. Isolated from the from the "imperfect" fungus Cylindrocladium iliciola strain MFC-870.ilicicolin H
piericidin aA member of the class of monohydroxypyridines that acts as an irreversible mitochondrial Complex I inhibitor that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of NADH:ubiquinone oxidoreductasepiericidin A
pyridoxalA pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.pyridoxal
pyridoxal phosphateThe monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.pyridoxal 5'-phosphate
pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acidAn arenesulfonic acid that is pyridoxal 5'-phosphate carrying an additional 2,4-disulfophenylazo substituent at position 6.5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid
pyridoxamineA monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy.pyridoxamine
pyridoxamine phosphateA vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine.pyridoxamine 5'-phosphate
pyridoxic acidA methylpyridine that is 2-methylpyridine substituted by a hydroxy group at C-3, a carboxy group at C-4, and a hydroxymethyl group at C-5. It is the catabolic product of vitamin B6 and is excreted in the urine.4-pyridoxic acid
pyridoxineA hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.pyridoxine
pyrithioneA pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.pyrithione

Research

Studies (14,252)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19908,002 (56.15)18.7374
1990's2,157 (15.13)18.2507
2000's1,992 (13.98)29.6817
2010's1,547 (10.85)24.3611
2020's554 (3.89)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials664 (3.71%)5.53%
Reviews1,113 (6.22%)6.00%
Case Studies760 (4.25%)4.05%
Observational10 (0.06%)0.25%
Other15,351 (85.77%)84.16%