Osseous Paget's Disease

Synonym
Paget's Disease of Bone
Osseous Paget's Disease
Paget Disease, Bone
Paget Disease of Bone

Excerpt	Reference
"Paget's disease of bone is most commonly seen in the spine; it may either be asymptomatic or may cause pain and neurologic impairment."	( Cooperstein, L; Goodman, M; Helfrich, DJ; Nicholas, JJ, 1989)
"Paget's disease of bone is characterized by the progressive and extensive replacement, in one or several bones, of normal bone tissue by a bone tissue of rough and irregular structure, the excessive and disorderly renewal of which gradually produces hyperdensity and hypertrophy of the bones involved."	( Renier, JC, 1989)
"Paget's disease of bone is now regarded as a slow virus disease of the skeleton presenting with localized manifestation."	( Ziegler, R, 1988)
"Paget's disease of bone is a slowly progressive and frequently disabling disorder of unknown cause."	( Ryan, WG, 1983)
"Paget's disease of bone is a process of increased bone remodeling resulting in architecturally abnormal bone that may affect any area of the skeleton."	( Lane, JM; Merkow, RL, 1984)
"Paget's disease of bone is characterized by focal resorption of existing bone followed by the deposition of woven and lamellar bone in a characteristic pattern."	( Krane, SM, 1980)
"Paget's disease of bone is a disorder of bone remodeling in which excessive production of structurally abnormal bone occurs, with the primary and fundamental abnormality residing in the osteoclast."	( Berná, L; Carrió, I; Díaz, C; Estorch, M; Farrerons, J; Torres, G, 1994)
"Paget's disease of bone is characterized by primary osteoclastic dysfunction and prolonged treatment with conventional medications including calcitonin and etidronate, results in a number of patients becoming refractory to treatment."	( Gunasekera, RD; Wimalawansa, SJ, 1993)
"Paget's disease of bone is a localized progressive disease, characterized by increased bone remodeling, bone hypertrophy, and abnormal bone structure, leading to pain and deformity."	( Meunier, PJ; Vignot, E, 1995)
"Paget's disease of bone is a disease with massive focal increase of bone turnover."	( Grauer, A; Klar, B; Knaus, J; Scharla, SH; Ziegler, R, 1996)
"Paget's disease of bone is characterized by a high bone turnover."	( Devogelaer, JP; Malghem, J; Nagant de Deuxchaisnes, C; Stasse, P, 1997)
"Paget's disease of bone is a chronic skeletal disease with areas of increased bone turnover leading to pain, deformity, and in some cases arthritis."	( Carson, CC; Gold, DT; Krishan, R; Lyles, KW; Newton, RA; Parekh, S; Pieper, CF; Shipp, KM, 1997)
"Paget's disease of bone is common in the elderly and is associated with increased osteoblastic and osteoclastic activity at affected sites in the skeleton."	( Cook, GJ; Fogelman, I; Maisey, MN, 1997)
"Paget's disease of bone is not associated with abnormal [18F]FDG uptake in the majority of patients and, therefore, there is potential for discriminating between benign Paget's disease and associated Paget's sarcoma."	( Cook, GJ; Fogelman, I; Maisey, MN, 1997)
"Paget's disease of bone is an uncommon condition in the Asian population, with only 2 cases reported in medical literature so far."	( Hsu, LF; Rajasoorya, C, 1998)
"Paget's disease of bone is usually asymptomatic."	( Carbonell, J; Gumà, M; Holgado, S; Monfort, J; Olivé, A; Rotés, D; Tena, X, 2002)
"Paget's disease of bone is a common condition with a strong genetic component, characterized by focal increases in bone turnover, affecting one or more bones throughout the skeleton."	( Langston, AL; Ralston, SH, 2004)
"PDB (Paget's disease of bone) is a common condition characterized by focal increases in bone turnover affecting one or more sites throughout the skeleton."	( Daroszewska, A; Ralston, SH, 2005)
"Paget's disease of bone is a common skeletal disorder of the elderly that often results in significant morbidity and disability."	( Maricic, M, 2006)
"Paget's disease of bone is characterized by alterations in skeletal metabolism, affecting a single or multiple bones."	( Blake, GM; Clarke, SE; Fogelman, I; Gnanasegaran, G; Moore, AE; Vijayanathan, S, 2007)
"Paget's disease of bone is characterised by a focal increase in bone resorption and bone formation."	( Devogelaer, JP; Manicourt, DH, 2007)
"Paget's disease of bone is a common skeletal disorder that often results in significant pain and disability."	( Maricic, M, 2007)
"Paget's disease of bone is a common disease characterised by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton."	( Langston, AL; Ralston, SH; Reid, IR, 2008)
"Paget's disease of bone is a common condition characterised by increased and disorganised bone turnover which can affect one or several bones throughout the skeleton."	( Ralston, SH, 2008)
"Paget disease of bone is a disorder of unknown etiology involving disturbances in bone remodeling, typically leading to bone pain and other complications such as skeletal deformities, fractures, hearing loss, and neurologic complications."	( Silverman, SL, 2008)
"Paget's disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain."	( De Paola, V; Gennari, L; Martini, G; Merlotti, D; Mossetti, G; Nuti, R; Rendina, D, 2009)
"Paget's disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, skeletal deformities, and other complications leading to bone pain and significant disability."	( Andrikoula, M; Gkouva, L; Kontogeorgakos, V; Papachristou, DJ; Tsatsoulis, A, 2011)
"Paget disease of bone is the most common metabolic bone disease after osteoporosis, affecting 2-4% of adults over 55 years of age."	( Britton, C; Walsh, J, 2012)
"Paget's disease of bone is a common metabolic bone disease in most of the European countries."	( Butt, R; Butt, ST; Fatima, S; Irfan, J; Jameel, G; Nasir, W, 2012)
"Paget's disease of bone is a common disorder characterized by increased but disorganized bone remodelling."	( Ralston, SH; Tan, A, 2014)
"Paget's disease of bone is a common skeletal disorder of the elderly."	( Al Nofal, AA; Altayar, O; Asi, N; BenKhadra, K; Murad, MH; Nabhan, M; Prokop, LJ; Qasim Agha, OQ; Tebben, P, 2015)
"Paget disease of bone is a chronic metabolic bone disorder characterized by increased bone resorption and new bone formation."	( Adami, G; Braga, V; Fassio, A; Gatti, D; Idolazzi, L; Rossini, M; Tripi, G; Viapiana, O, 2017)
"Paget's disease of bone is characterised by overactive osteoclasts that resorb bone at a higher rate than normal."	( Condon, JR, 2019)
"Familial Paget's disease of bone is inherited as an autosomal-dominant trait and mutations in the sequestosome 1 (SQSTM1) gene have been reported with variable frequency in patients with familial disease."	( Appelman-Dijkstra, NM; Boudin, E; De Ridder, R; Eekhoff, EMW; Hamoen, EC; Papapoulos, SE; Peeters, JJM; Smit, F; Van Hul, W, 2019)
"Paget disease of bone is a benign disorder characterized by focal areas of increased bone turnover in one or more skeletal sites."	( des Bordes, JK; Rianon, NJ, 2020)

Excerpt	Reference
"Its oral use in Paget's disease of bone has proved effective and safe when the drug is administered on a long-term basis."	( Burckhardt, P; Jaeger, P; Thiébaud, D, 1986)
"Control of Paget's disease of bone has been possible through treatment with agents that decrease bone resorption; calcitonins, diphosphonates, and mithramycin."	( Krane, SM, 1982)
"Paget disease of bone has an unknown etiology, having complex pathogenesis leading to increased bone resorption in the first phase and an excess of bone formation with more advanced disease."	( Contreras, AS; Iglesias-Gamarra, A; Patarroyo, PA; Restrepo, JF; Rojas-Villarraga, A, 2006)
"Paget's disease of bone has been described as a few case reports from India."	( Bhadada, S; Bhansali, A; Khadgawat, R; Mithal, A; Saikia, UN; Singh, SK; Unnikrishnan, AG, 2006)

Excerpt	Reference
"Paget's disease of bone affects one or more bones and is characterized by increased bone turnover (remodelling) with hypertrophy and abnormal bone structure with diminished strength leading to deformity and fracture."	( Bijlsma, JW; Huisman, AM; Jacobs, JW; van Paassen, HC, 1999)
"Paget's disease of bone affects 10% of those surviving to the eighth decade of life."	( Rothschild, BM, 2000)

Excerpt	Reference
"Its major therapeutic effect is in the treatment of Paget's Disease of bone, in which it has been shown to reduce bone pain, lead to radiological and histological improvement in bone, and to restore abnormal biochemistry towards normal."	( Martin, TJ, 1978)
"Several agents are available for treatment of Paget's disease of bone, but their long-term use may be limited by resistance or adverse effects."	( Mallette, LE, 1989)
"13 patients with polyosseous Paget's disease were treated for a mean period of 7 months with disodium etidronate (EHDP, ethylidene-1-hydroxy-1,1-diphosphonate); the average daily dosage was 5 mg/kg body weight."	( Frühwald, F; Kolbe, H; Kovarik, J; Niebauer, B; Woloszczuk, W, 1985)
"The essential requirement for effective treatment of Paget's disease of bone is that the characteristic abnormality of bone remodelling is predictably corrected without the occurrence of significant side effects."	( Hosking, DJ, 1985)
"In untreated Paget's disease of bone there is a striking increase, which is proportional to the biochemical severity of the disease : total blood flow to the skeleton is approximately doubled at an alkaline phosphatase of 50 KAu/dl (i."	( Green, JR; Reeve, J; Tellez, M; Wootton, R, 1981)
"Calcitonin has been used in the treatment of Paget's disease of bone, and serum alkaline phosphatase level and 24 hr urinary hydroxyproline excretion have been used to follow therapeutic response."	( McKee, D; Siemsen, JK; Singer, FR; Waxman, AD, 1980)
"The ideal treatment for Paget's disease of bone should control turnover irrespective of its initial activity and produce a sustained remission once treatment is withdrawn."	( Hosking, DJ, 1981)
"Pamidronate treatment for Paget's disease of bone leads to a sustained inhibition of elevated bone turnover."	( Grauer, A; Klar, B; Knaus, J; Scharla, SH; Ziegler, R, 1996)
"They are used in the treatment of Paget's disease of bone, hypercalcaemia and osteolytic bone disease of malignancy, primary and secondary hyperparathyroidism, and in osteoporosis."	( Vasikaran, SD, 2001)
"Bisphosphonates are the mainstay of the treatment of Paget's disease of bone (PDB)."	( Abu Tailakh, M; Liel, Y, 2019)
"Early diagnosis of Paget disease of bone remains key to its management because patients generally have a good prognosis if treatment is initiated before major complications arise."	( des Bordes, JK; Rianon, NJ, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	990 (54.70)	23.3326
1990's	357 (19.72)	12.5806
2000's	262 (14.48)	18.1394
2010's	165 (9.12)	28.8240
2020's	36 (1.99)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
ammonium hydroxide	low	1	0
anthranilic acid	low	1	0
choline	low	1	0
citric acid, anhydrous	low	3	0
chlorine	low	4	0
salicylic acid	low	1	0
creatine	medium	4	1
glycine	low	3	0
hydrogen carbonate	low	2	0
iodine	low	2	0
methanol	low	1	0
inositol	low	2	0
nickel	low	2	0
niacinamide	low	1	0
phenol	low	1	0
diphosphoric acid	low	1	0
pyridoxine	low	1	0
uric acid	low	12	0
urea	low	5	0
aminopropionitrile	low	1	0
phenytoin	low	3	0
albuterol	low	1	0
alendronate	medium	53	12
amifostine anhydrous	low	1	0
theophylline	low	2	0
amitriptyline	low	1	0
aspirin	low	10	0
bendroflumethiazide	low	1	0
benzothiazide	low	1	0
bupivacaine	low	1	0
caffeine	low	1	0
chloroquine	low	2	0
chlorthalidone	low	1	0
clofibrate	low	1	0
dapi	low	1	0
dapsone	low	1	0
pentetic acid	low	1	0
etidronate	medium	254	34
flurbiprofen	low	1	0
flutamide	low	1	0
furosemide	low	1	0
indomethacin	low	6	0
ipriflavone	medium	4	1
2-propanol	low	2	0
mefenamic acid	low	1	0
methyclothiazide	medium	2	1
pamidronate	medium	175	27
phenobarbital	low	1	0
phenylbutazone	low	5	0
probenecid	low	1	0
sodium fluoride	low	14	0
risedronic acid	medium	48	9
sulfisoxazole	low	1	0
sulfoxone	low	1	0
thalidomide	low	1	0
urethane	low	1	0
prednisolone	low	3	0
estriol	low	1	0
hydroxyproline	medium	341	44
thyroxine	low	4	0
aldosterone	low	2	0
penicillamine	low	2	0
norethandrolone	low	1	0
prednisone	low	6	0
carbon tetrachloride	low	1	0
aspartic acid	low	1	0
lysine	low	3	0
testosterone propionate	low	1	0
adenosine diphosphate	medium	3	1
galactose	low	2	0
levodopa	low	1	0
edetic acid	low	10	0
tyrosine	low	2	0
adenosine monophosphate	low	2	0
methylene blue	low	1	0
leucine	low	1	0
methionine	low	1	0
phenylalanine	low	2	0
desoxycorticosterone	low	1	0
colchicine	low	7	0
triaziquone	low	1	0
cytarabine	low	2	0
histidine	medium	2	1
tryptophan	low	2	0
arginine	medium	5	1
methylene chloride	low	1	0
2,2-dimethoxypropane	low	1	0
methylprednisolone	low	1	0
tolonium chloride	low	1	0
thiophenes	low	2	0
iodohippuric acid	low	1	0
thiamine pyrophosphate	low	1	0
nitroblue tetrazolium	low	1	0
calcium gluconate	low	1	0
diiodotyrosine	low	1	0
limestone	low	3	0
podophyllotoxin	low	1	0
copper gluconate	low	2	0
acetylcysteine	low	1	0
c.i. 42510	low	2	0
durapatite	low	3	0
thorium dioxide	medium	1	1
carbonates	low	1	0
norleucine	low	1	0
samarium	low	1	0
technetium	low	87	0
thorium	low	1	0
titanium	low	2	0
americium	low	1	0
argon	low	1	0
cadmium	low	1	0
gadolinium	low	1	0
uranium	low	1	0
tricalcium phosphate	low	6	0
silver nitrate	low	2	0
fluorine	low	20	0
thallium chloride	low	1	0
radon	low	1	0
trolamine salicylate	low	44	0
stanozolol	low	1	0
clodronic acid	medium	48	5
ammonium chloride	low	1	0
origen	low	1	0
urobilinogen	low	1	0
levamisole	low	1	0
pizotyline	low	1	0
fluorides	medium	37	2
daunorubicin	low	1	0
cetylpyridinium chloride anhydrous	low	1	0
tobramycin	low	1	0
etoposide	low	1	0
1-carboxyglutamic acid	low	2	0
propiconazole	low	10	0
fomesafen	low	1	0
lovastatin	low	1	0
raloxifene hydrochloride	low	1	0
ibandronic acid	medium	8	2
tiludronic acid	medium	31	14
gallium nitrate	medium	9	3
efavirenz	low	1	0
fluorophosphate	low	1	0
proadifen hydrochloride	low	1	0
5-bromo-4-chloro-3-indoxyl phosphate	low	1	0
xenon radioisotopes	low	1	0
fluorodeoxyglucose f18	low	13	0
zoledronic acid	medium	82	14
6-amino-1-hydroxyhexane-1,1-diphosphonate	medium	9	3
nsc-172755	low	1	0
fibrinogen	low	1	0
sr141716	low	1	0
pyridinoline	medium	22	4
deoxypyridinoline	medium	27	6
deoxyglucose	low	1	0
nitroflurbiprofen	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	12	0
technetium tc 99m etidronate	low	5	0
galactosylhydroxylysine	medium	4	2
succinylglycyl-prolyl-leucyl-glycyl-prolyl-4-methylcoumaryl-7-amide	low	1	0
methotrexate	low	1	0
reveromycin a	low	2	0
xylose	low	1	0
galactosylpyridinoline	low	1	0
proline	medium	10	1
cinacalcet	low	1	0
technetium tc 99m (sn)methylenediphosphonate	low	1	0
organophosphonates	low	32	0
olpadronic acid	medium	8	3
demecolcine	low	1	0
cortisone	low	20	0
bortezomib	low	1	0
n-acetylneuraminic acid	low	2	0
bradykinin	low	2	0
elastin	low	1	0
mevalonic acid	low	1	0
tartaric acid	low	2	0
adenosine 5'-o-(3-thiotriphosphate)	low	1	0
griseofulvin	low	1	0
abacavir	low	1	0
tretinoin	low	1	0
resveratrol	low	1	0
retinol	low	6	0
fluciclovine f-18	low	1	0
dactinomycin	low	14	0
melphalan	low	1	0
tenofovir	low	1	0
bromochloroacetic acid	low	1	0
glycosides	low	4	0
isomethyleugenol	low	1	0
pyrophosphate	medium	17	1
thioguanine anhydrous	low	1	0
digoxin	low	1	0
tamoxifen	low	1	0
lithium	low	2	0
dermatan sulfate	low	1	0
hydroxylysine	medium	12	2
e 7010	low	1	0
ML162	low	1	0
osteoprotegerin	medium	64	1
sphingosine	low	1	0
bilirubin	low	2	0
dinoprostone	low	1	0
calcitriol	medium	38	4
vitamin k semiquinone radical	low	6	0
vitamin d 2	medium	6	1
cholecalciferol	medium	11	1
isotretinoin	low	1	0
sphingosine 1-phosphate	low	1	0
phenylephrine hydrochloride	low	2	0
sirolimus	low	3	0
clobetasol	low	1	0
ciguatoxins	low	1	0
licochalcone a	low	1	0
stilbamidine	low	1	0
lead	low	3	0
tin	low	2	0
barium	low	1	0
aluminum	low	4	0
strontium	low	8	0
bismuth	low	1	0
thallium	low	1	0
arsenic	low	1	0
indium	low	3	0
gallium	medium	10	3
sulfur	low	1	0
cysteine	low	1	0
phosphorus	medium	58	5
strontium radioisotopes	low	9	0
25-hydroxyvitamin d 2	low	2	0
radium	low	2	0
oxalates	low	1	0
24,25-dihydroxyvitamin d 3	low	7	0
everolimus	low	1	0
gadolinium dtpa	medium	3	1
1,25-dihydroxyergocalciferol	medium	1	1
tei 9647	low	3	0
technetium tc 99m diphosphonate	low	4	0
ripasudil	low	1	0
dactolisib	low	1	0
podophyllin	low	2	0
dihydrotachysterol	low	2	0
acid phosphatase	medium	41	3
jaw	low	15	0
nad	low	1	0
calcitonin	medium	35	2
glucagon	medium	22	1
beta-endorphin	medium	1	1
c-peptide	low	1	0
cellulose	low	1	0
endothelin-1	low	2	0
cnf 2024	low	1	0
n,n'-bis(2-hydroxy-5-(ethylene-beta-carboxy)benzyl)ethylenediamine n,n'-diacetic acid	low	1	0
technetium tc 99m sestamibi	low	2	0
sodium pertechnetate tc 99m	low	1	0
piperidines	low	1	0
interleukin-8	low	1	0
pf-4708671	low	1	0
chondroitin	low	2	0
ascorbic acid	low	3	0
tetracycline	low	3	0
chlortetracycline	low	1	0
oxytetracycline, anhydrous	low	1	0
salicylates	low	2	0
warfarin	low	2	0
epidermal growth factor	low	2	0
transforming growth factor beta	low	2	0
agar	low	1	0
technetium tc 99m sulfur colloid	low	2	0
nitrophenols	low	1	0
oxyntomodulin	low	1	0
transforming growth factor alpha	low	1	0
calcitonin, salmon, gly(8)-	low	1	0
gallium ga 68 dotatate	low	1	0
technetium tc 99m medronate	low	68	0
lutetium lu 177 dotatate	low	1	0
exudates	low	1	0
technetium tc 99m dimercaptosuccinic acid	low	1	0
cyclic gmp	low	2	0
inosine	low	1	0
rifampin	low	1	0
allopurinol	low	2	0
rifapentine	low	1	0
inosine pranobex	low	1	0
nms-e973	low	1	0
eye	low	7	0
carbidopa	low	1	0

Protein Targets (1,975)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	25	0	0	25
RAR-related orphan receptor gamma	61	0	0	61
GLI family zinc finger 3	55	0	0	55
AR protein	80	0	0	80
aldehyde dehydrogenase 1 family, member A1	42	0	0	42
retinoic acid nuclear receptor alpha variant 1	60	0	0	60
retinoid X nuclear receptor alpha	50	0	0	50
estrogen nuclear receptor alpha	84	0	0	84
peroxisome proliferator-activated receptor delta	40	0	0	40
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	39	0	0	39
activating transcription factor 6	25	0	0	25
v-jun sarcoma virus 17 oncogene homolog (avian)	31	0	0	31
Histone H2A.x	20	0	0	20
thyroid hormone receptor beta isoform a	26	0	0	26
heat shock protein beta-1	22	0	0	22
nuclear factor erythroid 2-related factor 2 isoform 1	64	0	0	64
lamin isoform A-delta10	40	0	0	40
Voltage-dependent calcium channel gamma-2 subunit	39	0	0	39
Glutamate receptor 2	39	0	0	39
Geranylgeranyl pyrophosphate synthase	0	8	0	9
Farnesyl pyrophosphate synthase	0	14	0	14
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	30	0	0	30
Chain A, HADH2 protein	20	0	0	20
Chain B, HADH2 protein	20	0	0	20
Chain A, ATP-DEPENDENT DNA HELICASE Q1	10	0	0	10
Chain A, Ferritin light chain	22	0	0	22
Chain A, Cruzipain	14	0	0	14
endonuclease IV	9	0	0	9
thioredoxin reductase	30	0	0	30
USP1 protein, partial	39	0	0	39
regulator of G-protein signaling 4	19	0	0	19
estrogen-related nuclear receptor alpha	64	0	0	64
euchromatic histone-lysine N-methyltransferase 2	63	0	0	63
Bloom syndrome protein isoform 1	25	0	0	25
cytochrome P450 2D6 isoform 1	6	0	0	6
cytochrome P450 2C19 precursor	8	0	0	8
cytochrome P450 2C9 precursor	11	0	0	11
D(1A) dopamine receptor	6	0	0	6
chromobox protein homolog 1	33	0	0	33
potassium voltage-gated channel subfamily H member 2 isoform d	19	0	0	19
DNA polymerase beta	8	0	0	8
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
DNA polymerase eta isoform 1	9	0	0	9
DNA polymerase iota isoform a (long)	27	0	0	27
geminin	68	0	0	68
DNA polymerase kappa isoform 1	16	0	0	16
cytochrome P450 3A4 isoform 1	26	0	0	26
M-phase phosphoprotein 8	15	0	0	15
histone acetyltransferase KAT2A isoform 1	18	0	0	18
Gamma-aminobutyric acid receptor subunit pi	26	1	0	27
Gamma-aminobutyric acid receptor subunit beta-1	26	1	0	27
Gamma-aminobutyric acid receptor subunit delta	26	1	0	27
Gamma-aminobutyric acid receptor subunit gamma-2	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-5	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-3	26	1	0	27
Gamma-aminobutyric acid receptor subunit gamma-1	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-2	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-4	26	1	0	27
Gamma-aminobutyric acid receptor subunit gamma-3	26	1	0	27
Gamma-aminobutyric acid receptor subunit alpha-6	26	1	0	27
Histamine H2 receptor	21	1	0	23
Gamma-aminobutyric acid receptor subunit alpha-1	26	2	0	28
Gamma-aminobutyric acid receptor subunit beta-3	26	1	0	27
Gamma-aminobutyric acid receptor subunit beta-2	26	1	0	27
GABA theta subunit	26	1	0	27
Gamma-aminobutyric acid receptor subunit epsilon	26	1	0	27
ATP-dependent phosphofructokinase	25	0	0	25
Luciferase	23	0	0	23
cytochrome P450 family 3 subfamily A polypeptide 4	46	0	0	46
cytochrome P450 2D6	28	0	0	28
peripheral myelin protein 22	33	0	0	33
Albumin	0	4	4	8
ATP-dependent translocase ABCB1	0	13	1	20
Replicase polyprotein 1ab	0	5	2	7
Replicase polyprotein 1ab	0	7	2	9
Reverse transcriptase/RNaseH	0	6	3	16
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	7	1	10
Chain A, JmjC domain-containing histone demethylation protein 3A	12	0	0	12
Chain A, 2-oxoglutarate Oxygenase	23	0	0	23
acetylcholinesterase	16	0	0	16
dopamine D1 receptor	5	0	0	5
15-lipoxygenase, partial	14	0	0	14
pregnane X receptor	14	0	0	14
phosphopantetheinyl transferase	29	0	0	29
NFKB1 protein, partial	4	0	0	4
Microtubule-associated protein tau	30	0	0	30
Thrombopoietin	2	0	0	2
glucocorticoid receptor [Homo sapiens]	69	0	0	69
farnesoid X nuclear receptor	39	0	0	39
vitamin D (1,25- dihydroxyvitamin D3) receptor	39	0	0	39
arylsulfatase A	15	0	0	15
thyroid hormone receptor beta isoform 2	54	0	0	54
flap endonuclease 1	16	0	0	16
survival motor neuron protein isoform d	24	0	0	24
muscarinic acetylcholine receptor M1	13	0	0	13
Histone deacetylase 3	0	3	0	3
Solute carrier family 22 member 6	0	6	0	6
Histone deacetylase 4	0	2	0	2
Guanine nucleotide-binding protein G	6	0	0	6
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	4	0	4
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Ataxin-2	34	0	0	34
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	6	0	6
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	63	0	0	63
nuclear receptor subfamily 1, group I, member 3	40	0	0	40
pregnane X nuclear receptor	53	0	0	53
nuclear factor erythroid 2-related factor 2 isoform 2	26	0	0	26
importin subunit beta-1 isoform 1	6	0	0	6
snurportin-1	6	0	0	6
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Bile salt export pump	0	61	0	61
Cyclin-dependent kinase 1	0	1	4	5
Heat shock protein HSP 90-beta	0	5	4	11
Xanthine dehydrogenase/oxidase	0	4	0	4
TAR DNA-binding protein 43	15	0	0	15
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	30	0	0	30
Chain A, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	2	2
Chain D, DNA polymerase III subunit gamma	0	0	2	2
Mu-type opioid receptor	0	2	2	4
Delta-type opioid receptor	0	2	2	4
Kappa-type opioid receptor	0	2	2	4
P2Y purinoceptor 2	0	0	3	3
P2X purinoceptor 1	0	0	2	2
P2Y purinoceptor 1	0	0	3	3
P2X purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	2	2
P2X purinoceptor 4	0	0	2	2
P2X purinoceptor 5	0	0	2	2
P2X purinoceptor 6	0	0	2	2
P2X purinoceptor 3	0	0	2	2
P2Y purinoceptor 11	0	0	3	3
P2Y purinoceptor 12	0	1	2	3
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	4	3	9
2-dehydropantoate 2-reductase	0	2	2	4
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	1	1	2
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	1	0	2
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	3	0	3
Endoplasmin	0	2	1	3
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2Y purinoceptor 1	0	0	2	2
Inositol monophosphatase 1	10	0	0	10
Heat shock protein 75 kDa, mitochondrial	0	3	0	3
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	2
Transient receptor potential cation channel subfamily M member 2	0	2	0	2
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	2
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	7	0	8
Fructose-1,6-bisphosphatase 1	0	1	0	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Cytochrome P450 2C9	0	15	1	17
Proto-oncogene tyrosine-protein kinase Src	0	2	4	6
Amine oxidase [flavin-containing] B	0	1	0	1
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	7	3	14
Adenylate kinase isoenzyme 1	0	1	0	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	6	7
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
Adenylate kinase 2, mitochondrial	0	0	4	6
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	6	7
Adenosine deaminase-like protein	0	0	0	1
Protease	0	2	1	4
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	5	6
5'-AMP-activated protein kinase subunit beta-1	0	0	2	3
glp-1 receptor, partial	14	0	0	14
GLS protein	20	0	0	20
NPYLR7B	0	0	1	1
thyroid stimulating hormone receptor	23	0	0	23
ATP-binding cassette sub-family C member 3	0	41	0	41
Multidrug resistance-associated protein 4	0	42	0	45
Beta-2 adrenergic receptor	0	2	2	4
Beta-1 adrenergic receptor	0	2	2	4
60 kDa chaperonin	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	5	0	5
Beta-3 adrenergic receptor	0	2	1	3
Delta-type opioid receptor	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	5	0	5
Thiosulfate sulfurtransferase	0	5	0	5
Beta-2 adrenergic receptor	0	0	1	3
60 kDa chaperonin	0	5	0	5
10 kDa chaperonin	0	5	0	5
Beta-2 adrenergic receptor	0	1	2	3
Canalicular multispecific organic anion transporter 1	0	44	0	45
Sex hormone-binding globulin	0	0	4	4
Corticosteroid-binding globulin	0	5	0	5
Mineralocorticoid receptor	0	3	3	6
Androgen receptor	0	14	0	14
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	4
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Acetylcholinesterase	0	5	0	5
Hypoxanthine-guanine phosphoribosyltransferase	0	3	0	3
Farnesyl pyrophosphate synthase	0	6	0	6
Farnesyl pyrophosphate synthase	0	3	0	3
interleukin 8	12	0	0	12
thyroid stimulating hormone receptor	21	0	0	21
estrogen receptor 2 (ER beta)	36	0	0	36
progesterone receptor	39	0	0	39
IDH1	25	0	0	25
transcriptional regulator ERG isoform 3	8	0	0	8
ras-related protein Rab-9A	10	0	0	10
Polyphenol oxidase 2	0	4	0	8
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Cellular tumor antigen p53	50	0	0	50
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	6	4	12
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Purine nucleoside phosphorylase	0	0	1	1
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	1	0	1
D(3) dopamine receptor	0	6	0	6
Spike glycoprotein	23	1	2	26
ATAD5 protein, partial	16	0	0	16
Lysyl oxidase homolog 2	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	6	0	0	6
Solute carrier family 22 member 1	0	2	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	0	0	10
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
5-hydroxytryptamine receptor 4	0	4	1	5
Albumin	0	0	2	2
High affinity nerve growth factor receptor	0	2	5	7
Aldo-keto reductase family 1 member B1	0	10	0	10
Muscarinic acetylcholine receptor M2	0	6	0	6
Muscarinic acetylcholine receptor M4	0	5	0	5
Muscarinic acetylcholine receptor M1	0	1	1	2
Muscarinic acetylcholine receptor M3	0	1	1	2
Muscarinic acetylcholine receptor M4	0	1	1	2
5-hydroxytryptamine receptor 2C	0	2	0	3
Muscarinic acetylcholine receptor M5	0	1	1	2
Muscarinic acetylcholine receptor M5	0	5	0	5
Alpha-2A adrenergic receptor	0	5	0	5
Muscarinic acetylcholine receptor M2	0	1	1	2
Muscarinic acetylcholine receptor M1	0	6	0	6
Angiotensin-converting enzyme	0	4	0	4
D(2) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	2	0	2
Alpha-2B adrenergic receptor	0	7	1	8
Alpha-2C adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 1A	0	6	0	8
Muscarinic acetylcholine receptor M3	0	5	0	5
D(1A) dopamine receptor	0	4	0	4
D(1B) dopamine receptor	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	2
Sodium-dependent noradrenaline transporter	0	10	2	12
Histamine H2 receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	5	0	5
5-hydroxytryptamine receptor 2A	0	5	0	5
5-hydroxytryptamine receptor 2C	0	5	0	5
5-hydroxytryptamine receptor 1B	0	4	0	4
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	7	1	8
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Histamine H1 receptor	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 4 subunit alpha	0	2	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	9	0	9
Alpha-1A adrenergic receptor	0	13	0	13
D(1A) dopamine receptor	4	0	0	4
5-hydroxytryptamine receptor 6	0	7	0	7
5-hydroxytryptamine receptor 7	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Sodium-dependent dopamine transporter	0	6	0	6
Potassium voltage-gated channel subfamily H member 2	0	11	0	11
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	1	2
5-hydroxytryptamine receptor 4	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	4	0	4
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	5	1	6
5-hydroxytryptamine receptor 3B	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	3	0	3
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Nuclear receptor ROR-gamma	17	3	2	22
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
alpha-galactosidase	8	0	0	8
lethal factor (plasmid)	15	0	0	15
Cytochrome P450 3A4	0	16	2	20
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	14	0	0	14
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	20	0	0	20
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	20	0	29
Carbonic anhydrase 2	0	21	1	31
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	2
Glutamate receptor ionotropic, NMDA 1	0	5	1	12
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	11
Glutamate receptor ionotropic, NMDA 2B	0	4	1	11
Glutamate receptor ionotropic, NMDA 2C	0	4	1	11
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	6
Glutamate receptor ionotropic, NMDA 2D	0	4	1	11
Glutamate receptor ionotropic, NMDA 3B	0	4	1	11
Carbonic anhydrase 4	0	0	0	2
Glutamate receptor ionotropic, NMDA 3A	0	4	1	11
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	3	0	0	3
EWS/FLI fusion protein	30	0	0	30
glucocerebrosidase	7	0	0	7
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	11	0	0	11
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	3
Prostaglandin G/H synthase 2	0	2	0	3
Epidermal growth factor receptor	0	5	4	9
Fatty acid-binding protein, liver	0	4	1	5
Integrin beta-3	7	1	0	8
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	9	1	11
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	7	1	0	8
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	10	0	10
Adenosine receptor A1	0	7	0	13
Adenosine receptor A2a	0	6	0	14
Substance-P receptor	0	3	0	3
Prostaglandin G/H synthase 2	0	11	1	12
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	5	0	5
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	5	0	5
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	14	0	0	14
G	30	0	0	30
bromodomain adjacent to zinc finger domain 2B	11	0	0	11
pyruvate kinase PKM isoform a	2	0	0	2
Interferon beta	47	0	0	47
HLA class I histocompatibility antigen, B alpha chain	30	0	0	30
Inositol hexakisphosphate kinase 1	30	0	0	30
cytochrome P450 2C9, partial	30	0	0	30
vitamin D3 receptor isoform VDRA	26	0	0	26
caspase-1 isoform alpha precursor	4	0	0	4
Caspase-7	3	0	0	3
Solute carrier organic anion transporter family member 1B3	0	9	0	12
Solute carrier organic anion transporter family member 1B1	0	9	0	12
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
Fumarate hydratase	13	0	0	13
PPM1D protein	19	0	0	19
caspase 7, apoptosis-related cysteine protease	16	0	0	16
polyprotein	13	0	0	13
peroxisome proliferator activated receptor gamma	45	0	0	45
caspase-3	16	0	0	16
nuclear receptor subfamily 1, group I, member 2	13	0	0	13
Caspase-7	9	0	0	9
caspase-3	9	0	0	9
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	8	0	15
Prothrombin	0	1	0	2
Chymotrypsinogen A	0	2	0	2
Carbonic anhydrase 3	0	6	0	11
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	2	0	2
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	10	0	17
Carbonic anhydrase 6	0	7	0	14
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
Carbonic anhydrase 5A, mitochondrial	0	6	0	13
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	6	0	13
26S proteasome regulatory subunit 6B	0	1	4	5
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	2	0	2
Nuclear factor NF-kappa-B p100 subunit	0	2	0	2
Transcription factor p65	0	2	0	2
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	8	0	15
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	3	0	5
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	8	0	13
Carbonic anhydrase 14	0	7	0	14
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	6	0	13
Angiotensin-converting enzyme	0	2	0	3
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	4	1	7
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	1	4	5
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	0	3	3
Potassium channel subfamily K member 9	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	5	0	0	5
nuclear receptor ROR-gamma isoform 1	27	0	0	27
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Adenosine receptor A3	0	12	0	12
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	5	0	5
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2b	0	2	0	4
Adenosine receptor A2b	0	3	0	5
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	6	2	8
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	3	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	1	4
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	2	0	2
Serine-protein kinase ATM	0	2	0	2
Serine/threonine-protein kinase ATR	0	1	1	2
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	2	0	2
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	2	0	2
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Beta-lactamase	15	0	0	15
Vitamin D3 receptor	0	0	1	1
mitogen-activated protein kinase 1	12	0	0	12
Vitamin D-binding protein	0	0	1	1
Cytochrome P450 1A2	0	3	1	5
Androgen receptor	0	6	1	8
Cytochrome P450 2D6	0	5	2	7
Vitamin D3 receptor	0	3	3	10
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	5	7
Cytochrome P450 2C19	0	8	1	9
Kappa-type opioid receptor	0	1	1	3
Vitamin D3 receptor	0	0	2	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Cytochrome P450 2E1	0	2	0	2
Carbonic anhydrase	0	6	0	11
SMAD family member 2	20	0	0	20
SMAD family member 3	20	0	0	20
67.9K protein	20	0	0	20
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	5	0	0	5
thyrotropin-releasing hormone receptor	5	0	0	5
Caspase-2	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	2	3
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	0	8	1	9
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	2	2	4
Replicase polyprotein 1a	0	1	2	3
Replicase polyprotein 1ab	0	1	2	3
Spike glycoprotein	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	3	5	8
DNA ligase 1	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	2	2	4
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	4	0	4
Smad3	15	0	0	15
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Carbonic anhydrase 13	0	4	0	10
Glycine receptor subunit alpha-1	0	0	3	3
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	0	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	2	3	0	5
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	3	0	5
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	3	0	4
PINK1	2	0	0	2
Parkin	7	0	0	7
huntingtin isoform 2	8	0	0	8
Extracellular calcium-sensing receptor	0	0	1	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
aryl hydrocarbon receptor	25	0	0	25
Type IV secretion-like conjugative transfer relaxase protein TraI	0	2	0	2
72 kDa type IV collagenase	0	5	0	5
Stromelysin-1	0	3	1	4
Matrix metalloproteinase-9	0	3	0	3
Macrophage metalloelastase	0	1	0	1
GALC protein	5	0	0	5
peripheral myelin protein 22 isoform 1	12	0	0	12
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor alpha	1	0	1	2
Chain A, Heat shock protein HSP 90-alpha	0	1	0	1
PAX8	0	0	0	6
nuclear receptor subfamily 0 group B member 1	0	3	0	3
cellular tumor antigen p53 isoform a	8	0	0	8
steroidogenic factor 1	0	3	0	3
muscleblind-like protein 1 isoform 1	13	0	0	13
neuropeptide S receptor isoform A	8	0	0	8
Solute carrier family 22 member 3	0	1	0	1
Tubulin alpha-1A chain	0	5	2	7
Tubulin beta chain	0	5	2	7
Plasma kallikrein	0	0	0	6
Tubulin beta-4A chain	0	5	3	10
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	5	3	10
Tubulin alpha-3C chain	0	5	3	10
Serine/threonine-protein kinase pim-1	0	2	4	6
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin alpha-1B chain	0	5	3	10
Tubulin alpha-4A chain	0	5	3	10
Tubulin beta-4B chain	0	5	3	10
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	5	3	10
Tubulin beta-2A chain	0	5	3	10
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	5	3	10
Tubulin beta-2B chain	0	7	0	7
Tubulin alpha-3E chain	0	5	3	10
Tubulin alpha-1A chain	0	5	3	10
Similar to alpha-tubulin isoform 1	0	5	0	5
Similar to alpha-tubulin isoform 1	0	5	0	5
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	5	3	10
Tubulin beta-6 chain	0	5	3	10
Tubulin beta-2B chain	0	5	3	10
Tubulin beta-1 chain	0	5	3	10
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	15	0	0	15
Glucocorticoid receptor	0	13	2	20
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	3	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	5	0	6
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	4	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	4	0	4
nuclear receptor coactivator 3 isoform a	0	4	0	4
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	2	0	3
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	4	5
Probable deoxycytidylate deaminase	0	0	0	1
Cytidine deaminase	0	2	0	3
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Thymidine kinase	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	17	0	0	17
RAD51	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	4	5
Growth factor receptor-bound protein 2	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	4	4
Membrane-associated progesterone receptor component 1	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	0	4	4
ATP-dependent RNA helicase DDX3X	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	0	1
Pyridoxal kinase	0	0	4	5
Citron Rho-interacting kinase	0	0	4	4
Serine/threonine-protein kinase Chk1	0	1	4	5
Aurora kinase A	0	1	4	5
Cyclin-G-associated kinase	0	0	4	4
Ephrin type-B receptor 6	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 3	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 2	0	0	4	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	4	4
Dynamin-like 120 kDa protein, mitochondrial	0	0	4	4
Eukaryotic translation initiation factor 5B	0	0	4	4
Rho-associated protein kinase 2	0	2	4	6
Serine/threonine-protein kinase ULK1	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	4	4
Ribosomal protein S6 kinase alpha-5	0	0	4	4
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	4	4
Ribosomal protein S6 kinase alpha-4	0	0	4	4
Serine/threonine-protein kinase 16	0	0	4	4
Serine/threonine-protein kinase 10	0	0	4	4
Serine/threonine-protein kinase D3	0	1	4	5
Structural maintenance of chromosomes protein 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 6	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	4	4
Serine/threonine-protein kinase LATS1	0	0	4	4
Serine/threonine-protein kinase PAK 4	0	1	4	5
Tyrosine-protein kinase ABL1	0	2	5	8
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	3	3
ADP/ATP translocase 2	0	0	4	4
Protein kinase C beta type	0	2	4	6
Insulin receptor	0	1	4	5
Tyrosine-protein kinase Lck	0	4	4	8
Tyrosine-protein kinase Fyn	0	2	4	6
Glycogen phosphorylase, liver form	0	0	4	4
Tyrosine-protein kinase Fes/Fps	0	0	4	4
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	0	4	4
Tyrosine-protein kinase Lyn	0	0	4	4
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	4	5
Insulin-like growth factor 1 receptor	0	1	4	5
Signal recognition particle receptor subunit alpha	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	4	4
Hepatocyte growth factor receptor	0	1	4	5
Tyrosine-protein kinase HCK	0	0	4	4
Platelet-derived growth factor receptor beta	0	1	4	5
Serine/threonine-protein kinase A-Raf	0	0	4	4
Glycogen phosphorylase, brain form	0	0	4	4
Breakpoint cluster region protein	0	1	4	6
Fibroblast growth factor receptor 1	0	1	4	5
DNA topoisomerase 2-alpha	0	1	4	11
Cyclin-dependent kinase 4	0	0	4	4
ADP/ATP translocase 3	0	0	4	4
Inosine-5'-monophosphate dehydrogenase 2	0	0	4	4
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	4	4
Serine/threonine-protein kinase B-raf	0	0	4	4
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	4	4
Tyrosine-protein kinase Fer	0	0	4	4
Protein kinase C alpha type	0	1	5	6
cAMP-dependent protein kinase catalytic subunit alpha	0	0	4	4
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	4	4
Casein kinase II subunit alpha'	0	0	4	4
Ras-related protein Rab-6A	0	0	4	4
Ephrin type-A receptor 1	0	0	4	4
Multifunctional protein ADE2	0	0	4	4
cAMP-dependent protein kinase catalytic subunit gamma	0	0	3	3
cAMP-dependent protein kinase catalytic subunit beta	0	0	4	4
Ferrochelatase, mitochondrial	0	0	4	4
Tyrosine-protein kinase JAK1	0	1	4	5
Cyclin-dependent kinase 2	0	1	5	6
Beta-adrenergic receptor kinase 1	0	0	4	4
Probable ATP-dependent RNA helicase DDX6	0	0	4	4
Mitogen-activated protein kinase 3	0	1	4	5
MAP/microtubule affinity-regulating kinase 3	0	0	4	4
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	1	2
Mitogen-activated protein kinase 1	0	3	4	7
Ephrin type-A receptor 2	0	0	4	4
Ephrin type-B receptor 2	0	0	4	4
Non-receptor tyrosine-protein kinase TYK2	0	1	4	5
UMP-CMP kinase	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	3	3
Wee1-like protein kinase	0	0	4	4
Heme oxygenase 2	0	0	4	4
S-adenosylmethionine synthase isoform type-2	0	0	4	4
DnaJ homolog subfamily A member 1	0	0	4	4
RAC-alpha serine/threonine-protein kinase	0	1	4	5
RAC-beta serine/threonine-protein kinase	0	0	4	4
Dual specificity protein kinase TTK	0	1	4	5
DNA replication licensing factor MCM4	0	0	4	4
Myosin-10	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 2	0	0	4	4
Receptor-type tyrosine-protein kinase FLT3	0	1	4	5
Bone morphogenetic protein receptor type-1A	0	0	4	4
Activin receptor type-1B	0	0	4	4
TGF-beta receptor type-1	0	0	4	4
TGF-beta receptor type-2	0	0	3	3
Electron transfer flavoprotein subunit beta	0	0	3	3
Tyrosine-protein kinase CSK	0	0	4	4
Glycine--tRNA ligase	0	0	4	4
Protein kinase C iota type	0	1	4	5
Exosome RNA helicase MTR4	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Tyrosine-protein kinase Tec	0	0	4	4
Tyrosine-protein kinase ABL2	0	1	4	5
Tyrosine-protein kinase FRK	0	0	4	4
Tyrosine-protein kinase SYK	0	1	4	5
Mitogen-activated protein kinase 8	0	0	4	4
Mitogen-activated protein kinase 9	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 3	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	3	3
Casein kinase I isoform alpha	0	0	4	4
Casein kinase I isoform delta	0	0	4	4
MAP kinase-activated protein kinase 2	0	1	4	5
Elongation factor Tu, mitochondrial	0	0	4	4
Choline-phosphate cytidylyltransferase A	0	0	3	3
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	4	4
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	4	4
Dual specificity protein kinase CLK1	0	0	3	3
Dual specificity protein kinase CLK2	0	0	3	3
Glycogen synthase kinase-3 alpha	0	0	4	4
Glycogen synthase kinase-3 beta	0	1	4	5
Cyclin-dependent kinase 7	0	0	4	4
Cyclin-dependent kinase 9	0	0	4	4
Ras-related protein Rab-27A	0	0	4	4
Interleukin-1 receptor-associated kinase 1	0	0	4	4
Ribosomal protein S6 kinase alpha-3	0	0	4	4
Serine/threonine-protein kinase Nek2	0	0	4	4
Serine/threonine-protein kinase Nek3	0	0	4	4
Tyrosine-protein kinase JAK3	0	2	0	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	4	4
LIM domain kinase 1	0	0	4	4
LIM domain kinase 2	0	0	4	4
Tyrosine--tRNA ligase, cytoplasmic	0	0	3	3
Ephrin type-B receptor 3	0	0	4	4
Ephrin type-A receptor 5	0	0	4	4
Ephrin type-B receptor 4	0	0	4	4
Ephrin type-A receptor 4	0	0	4	4
Adenosine kinase	0	0	4	4
Ras-related protein Rab-10	0	0	4	4
Actin-related protein 3	0	0	4	4
Actin-related protein 2	0	0	4	4
GTP-binding nuclear protein Ran	0	0	4	4
Cyclin-dependent kinase 3	0	0	3	3
Cyclin-dependent kinase 6	0	0	4	4
Cyclin-dependent-like kinase 5	0	0	4	4
Cyclin-dependent kinase 16	0	0	4	4
Cyclin-dependent kinase 17	0	0	4	4
ATP-dependent 6-phosphofructokinase, platelet type	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 1	0	0	4	4
DNA topoisomerase 2-beta	0	1	5	12
Protein kinase C theta type	0	1	3	4
Activin receptor type-1	0	0	4	4
Macrophage-stimulating protein receptor	0	0	4	4
Focal adhesion kinase 1	0	1	4	5
Protein kinase C zeta type	0	1	3	4
Protein kinase C delta type	0	1	4	5
Tyrosine-protein kinase BTK	0	0	4	4
Activated CDC42 kinase 1	0	1	4	5
Epithelial discoidin domain-containing receptor 1	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	4	4
Serine/threonine-protein kinase 4	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 5	0	0	4	4
Mitogen-activated protein kinase 7	0	0	4	4
Serine/threonine-protein kinase PAK 2	0	0	3	3
Serine/threonine-protein kinase 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 1	0	0	4	4
Integrin-linked protein kinase	0	0	4	4
Rho-associated protein kinase 1	0	1	4	5
Non-receptor tyrosine-protein kinase TNK1	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	4	4
Activin receptor type-2B	0	0	4	4
Bone morphogenetic protein receptor type-2	0	0	4	4
Protein-tyrosine kinase 6	0	1	4	5
cGMP-dependent protein kinase 1	0	0	4	4
Cyclin-dependent kinase 13	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	4	4
Protein-tyrosine kinase 2-beta	0	0	4	4
Maternal embryonic leucine zipper kinase	0	1	4	5
Structural maintenance of chromosomes protein 1A	0	0	4	4
Chromodomain-helicase-DNA-binding protein 4	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 1	0	0	4	4
Serine/threonine-protein kinase 38	0	0	1	1
Ephrin type-A receptor 7	0	0	2	2
Delta(24)-sterol reductase	0	0	4	4
Ribosomal protein S6 kinase alpha-1	0	0	4	4
Dual specificity testis-specific protein kinase 1	0	0	4	4
Myosin light chain kinase, smooth muscle	0	0	4	4
Mitogen-activated protein kinase 11	0	0	4	4
Serine/threonine-protein kinase STK11	0	0	4	4
Serine/threonine-protein kinase N1	0	0	4	4
Serine/threonine-protein kinase N2	0	0	4	4
Mitogen-activated protein kinase 14	0	2	4	6
Calcium/calmodulin-dependent protein kinase type IV	0	0	4	4
Mitogen-activated protein kinase kinase kinase 11	0	0	4	4
MAP kinase-activated protein kinase 3	0	0	1	1
AP2-associated protein kinase 1	0	0	4	4
Myosin light chain kinase 3	0	0	4	4
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	4	4
Rab-like protein 3	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	3	3
Serine/threonine-protein kinase MRCK gamma	0	0	4	4
Acyl-CoA dehydrogenase family member 10	0	0	4	4
Serine/threonine-protein kinase N3	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	4	4
Uncharacterized protein FLJ45252	0	0	4	4
Acyl-CoA dehydrogenase family member 11	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	4	4
Serine/threonine-protein kinase MARK2	0	0	4	4
Serine/threonine-protein kinase TAO1	0	0	4	4
STE20-related kinase adapter protein alpha	0	0	3	3
Myosin-14	0	0	4	4
AarF domain-containing protein kinase 1	0	0	4	4
ATP-dependent RNA helicase DDX42	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	4	4
MAP kinase-activated protein kinase 5	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	3	3
Regulatory-associated protein of mTOR	0	3	0	3
Misshapen-like kinase 1	0	0	3	3
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	4	4
Mitogen-activated protein kinase 15	0	0	3	3
Serine/threonine-protein kinase Nek9	0	0	4	4
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
ATP-dependent RNA helicase DDX1	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	4	4
Aurora kinase B	0	1	4	5
MAP/microtubule affinity-regulating kinase 4	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	4	4
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	4	4
EKC/KEOPS complex subunit TP53RK	0	0	4	4
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 5	0	0	4	4
Mitogen-activated protein kinase kinase kinase 3	0	0	4	4
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	4	4
Target of rapamycin complex subunit LST8	0	3	0	3
Nucleolar GTP-binding protein 1	0	0	3	3
Serine/threonine-protein kinase D2	0	0	4	4
NUAK family SNF1-like kinase 2	0	0	3	3
RNA cytidine acetyltransferase	0	0	4	4
Serine/threonine-protein kinase SIK2	0	0	4	4
STE20-like serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase TAO3	0	0	4	4
dCTP pyrophosphatase 1	0	0	4	4
Dual specificity protein kinase CLK4	0	0	3	3
Casein kinase I isoform gamma-1	0	0	4	4
Serine/threonine-protein kinase PAK 6	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	4	4
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
BMP-2-inducible protein kinase	0	0	4	4
Obg-like ATPase 1	0	0	3	3
Midasin	0	0	4	4
Interleukin-1 receptor-associated kinase 4	0	0	4	4
Mitogen-activated protein kinase kinase kinase 20	0	0	4	4
Cyclin-dependent kinase 12	0	0	4	4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	3	3
Serine/threonine-protein kinase 26	0	1	4	5
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	4	4
Serine/threonine-protein kinase NLK	0	0	4	4
Serine/threonine-protein kinase TBK1	0	0	4	4
Septin-9	0	0	4	4
Ribosomal protein S6 kinase alpha-6	0	0	4	4
TRAF2 and NCK-interacting protein kinase	0	0	4	4
Serine/threonine-protein kinase TAO2	0	0	4	4
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase 38-like	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 2	0	0	4	4
Thyroid hormone receptor-associated protein 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 3	0	0	4	4
Serine/threonine-protein kinase MRCK beta	0	0	4	4
Interleukin-1 receptor-associated kinase 3	0	0	4	4
Serine/threonine-protein kinase 24	0	0	3	3
Casein kinase I isoform gamma-3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 4	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	1
Prothrombin	0	2	0	2
Glandular kallikrein	0	1	0	1
Cell division protein FtsZ	0	0	1	2
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Bile salt export pump	0	10	0	10
Dihydrofolate reductase	0	3	0	3
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Transthyretin	0	2	1	4
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	1	0	0	1
Glutamate receptor 3	1	0	0	1
Glutamate receptor 4	1	0	0	1
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	5	0	7
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
urokinase-type plasminogen activator precursor	10	0	0	10
plasminogen precursor	10	0	0	10
urokinase plasminogen activator surface receptor precursor	10	0	0	10
Solute carrier family 22 member 3	0	1	0	1
STAT3, partial	0	1	1	2
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
tumor necrosis factor	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	12	0	0	12
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	1	1	2
Solute carrier organic anion transporter family member 1A4	0	3	0	5
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 1A4	0	0	0	1
RGS12	1	0	0	1
WRN	3	0	0	3
eyes absent homolog 2 isoform a	2	0	0	2
C-terminal-binding protein 1	1	0	0	1
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier family 22 member 6	0	5	0	9
Solute carrier family 22 member 7	0	1	0	4
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 8	0	6	0	10
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	2	0	5
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	2	0	4
Ornithine transcarbamylase, mitochondrial	0	1	0	1
Nociceptin receptor	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
Eyes absent homolog 2	0	2	0	2
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, POL POLYPROTEIN	0	1	0	1
Chain B, POL POLYPROTEIN	0	1	0	1
Chain A, Pol Polyprotein	0	1	0	1
Chain B, Pol Polyprotein	0	1	0	1
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Cytochrome P450 2B6	0	2	1	4
Acetylcholinesterase	0	0	0	1
Cannabinoid receptor 1	0	5	1	6
Microsomal triglyceride transfer protein large subunit	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	1	0	2
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120	0	1	0	1
Fructose-1,6-bisphosphatase 1	0	0	0	1
Reverse transcriptase	0	1	1	2
Cholesterol 24-hydroxylase	0	0	1	1
Endothelin-1 receptor	0	3	0	3
Estrogen receptor	0	10	1	12
Polyunsaturated fatty acid lipoxygenase ALOX15	0	5	0	5
UDP-glucuronosyltransferase 2B7	0	0	0	2
Alpha-synuclein	4	5	0	9
Lanosterol 14-alpha demethylase	0	0	1	1
UDP-glucuronosyltransferase 1A10	0	1	0	2
acid sphingomyelinase	3	0	0	3
apical membrane antigen 1, AMA1	7	0	0	7
Regulatory protein E2	0	0	2	2
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2	0	0	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	4
Serum paraoxonase/arylesterase 1	0	4	0	4
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Integrase	0	2	0	2
Cell division cycle 7-related protein kinase	0	1	2	3
Tyrosine-protein kinase Fgr	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Ribosomal protein S6 kinase beta-1	0	2	3	5
G protein-coupled receptor kinase 6	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	2	3
Mitogen-activated protein kinase 10	0	0	3	3
Casein kinase I isoform gamma-2	0	0	3	3
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	3	3
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
histone deacetylase 9 isoform 3	6	0	0	6
Acid-sensing ion channel 3	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Aldo-keto reductase family 1 member C4	0	3	0	3
Aldo-keto reductase family 1 member C3	0	5	0	5
Aldo-keto reductase family 1 member C2	0	4	0	4
Acid-sensing ion channel 1	0	1	0	1
Aldo-keto reductase family 1 member C1	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Prostaglandin G/H synthase 1	0	3	0	3
nonstructural protein 1	9	0	0	9
Cocaine esterase	0	1	0	2
Arylacetamide deacetylase	0	1	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Cytochrome P450 2J2	0	5	0	5
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	8	0	9
Serine racemase	0	1	0	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	1	0	5
Heme oxygenase 1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Lanosterol 14-alpha demethylase	0	3	0	3
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Carbonic anhydrase	0	0	0	5
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	1	0	6
Carbonic anhydrase	0	0	0	5
Carbonic anhydrase	0	1	0	6
Carbonic anhydrase	0	0	0	5
Glutamine synthetase	0	1	0	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	3	0	4
Aldo-keto reductase family 1 member B1	0	2	0	2
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	1	0	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	2	0	2
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Lactoylglutathione lyase	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain A, ADENOSINE DEAMINASE	0	1	0	1
Chain A, ADENOSINE DEAMINASE	0	1	0	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Purine nucleoside phosphorylase	0	0	0	1
Adenosylhomocysteinase	0	1	0	2
Adenosine deaminase	0	1	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Peptidylglycine alpha-amidating monooxygenase	0	0	0	1
BRCA1	2	0	0	2
SUMO-1-specific protease	0	1	0	1
SUMO1/sentrin specific peptidase 7	0	1	0	1
lysosomal alpha-glucosidase preproprotein	4	0	0	4
caspase-3 isoform a preproprotein	0	2	0	2
sentrin-specific protease 8	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
serine/threonine-protein kinase PLK1	3	0	0	3
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Alpha-1B adrenergic receptor	0	12	0	12
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
Rap guanine nucleotide exchange factor 4	4	0	0	4
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	5	0	5
Phospholipase A-2-activating protein	0	5	0	5
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
pyruvate kinase	2	0	0	2
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Solute carrier family 15 member 1	0	1	0	1
SLC16A10 protein	0	0	0	4
Monocarboxylate transporter 10	0	0	0	4
phosphoglycerate kinase	3	0	0	3
Isocitrate dehydrogenase [NADP] cytoplasmic	0	1	1	2
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	5
Chain A, Antigen Cd11a (p180)	0	1	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
bcl-2-related protein A1	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Insulin receptor	0	1	0	1
Integrin alpha-L	0	1	1	2
Substance-K receptor	0	4	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Aldo-keto reductase family 1 member B10	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	3	4
Dihydrofolate reductase	0	5	0	6
Beta-lactamase	0	1	0	1
Myc proto-oncogene protein	0	2	0	3
Malate dehydrogenase, cytoplasmic	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	3	0	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	3
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
luciferase	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
protein AF-9 isoform a	0	0	0	1
Vpr	2	0	0	2
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
POsterior Segregation	0	0	2	2
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	2	0	0	2
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	3	1	4
Alpha-1D adrenergic receptor	0	3	0	3
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	2	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	2
Nrf2	1	0	0	1
fatty acid synthase	0	1	0	1
melanocortin receptor 4	0	1	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Bcl-2-like protein 11	0	0	0	1
Phospholipid hydroperoxide glutathione peroxidase	0	0	1	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	1	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	1	4
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	1	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Eukaryotic elongation factor 2 kinase	0	1	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	0	2
Tyrosine-protein kinase JAK2	0	1	1	2
Mast/stem cell growth factor receptor Kit	0	1	0	1
Cyclin-A2	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Tyrosine-protein kinase ZAP-70	0	1	0	1
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
Serine/threonine-protein kinase haspin	0	1	0	1
Serine/threonine-protein kinase Nek6	0	1	0	1
Eukaryotic translation initiation factor 2-alpha kinase 3	0	1	0	1
Serine/threonine-protein kinase pim-2	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Rap guanine nucleotide exchange factor 3	6	0	0	6
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Lysozyme	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Endolysin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Cannabinoid receptor 1	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 3	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Regulatory protein E2	0	0	1	1
Regulatory protein E2	0	0	1	1
Calcium-activated potassium channel subunit alpha-1	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	3	0	4
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	5	1	6
Cytochrome P450 2B1	0	1	0	1
Cytochrome P450 1A1	0	1	0	1
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Cytochrome P450 4B1	0	1	0	1
Cytochrome P450 2A7	0	1	0	1
Cytochrome P450 3A7	0	1	0	1
Cytochrome P450 2F1	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
Cytochrome P450 4F8	0	1	0	1
Cytochrome P450 4A11	0	1	0	1
Cytochrome P450 4F3	0	1	0	1
Cytochrome P450 1B1	0	3	0	3
Cytochrome P450 2A13	0	1	0	1
Cytochrome P450 4A22	0	1	0	1
Vitamin D 25-hydroxylase	0	1	0	1
Cytochrome P450 2U1	0	1	0	1
Cytochrome P450 2W1	0	1	0	1
Cytochrome P450 2S1	0	1	0	1
Cytochrome P450 3A43	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
UDP-glucuronosyltransferase 1A7	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 8	0	2	0	2
Glutamate 5-kinase	0	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
Chain A, dATP pyrophosphohydrolase	0	1	0	1
Chain A, Adenylate cyclase type 5	0	1	0	1
Chain B, Adenylate cyclase type 2	0	1	0	1
Prolyl 4-hydroxylase, beta polypeptide	0	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	1	2
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Estrogen receptor	0	1	2	4
Gastric inhibitory polypeptide receptor	0	1	0	1
Estrogen receptor beta	0	1	2	4
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
P53	1	0	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Vif	0	1	0	1
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	2
Acetylcholinesterase	0	2	0	2
Lysine-specific histone demethylase 1A	0	1	0	1
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Leukotriene A-4 hydrolase	0	1	0	1
Tyrosinase	0	2	0	2
Aromatase	0	2	0	2
Ornithine decarboxylase	0	1	0	1
Estrogen receptor	0	0	1	2
Endothelin receptor type B	1	0	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Endothelin-1 receptor	1	1	0	2
Dipeptidyl peptidase 4	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
Cholinesterase	0	1	0	1
Squalene synthase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	4
Bcl-2-like protein 1	0	2	0	2
Serine/threonine-protein kinase PAK 1	0	1	0	1
Nuclear factor erythroid 2-related factor 2	0	0	1	2
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	2
Lysosomal alpha-glucosidase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	1	0	1
Prenyltransferase homolog	0	0	0	1
large T antigen	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	2
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Cyclin-dependent kinase-like 5	0	0	2	2
Butyrophilin subfamily 3 member A1	0	0	2	3
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
H	0	2	0	2
Phosphotransferase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Programmed cell death protein 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	2	0	2
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
streptokinase A precursor	0	0	2	2
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	2	0	2
Protein kinase C delta type	0	2	0	2
Protein kinase C epsilon type	0	2	0	2
Protein kinase C zeta type	0	2	0	2
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	2	0	2
Protein kinase C beta type	0	2	0	2
Protein kinase C eta type	0	2	0	2
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	2	0	2
Sphingosine 1-phosphate receptor 2	0	1	1	2
Sphingosine 1-phosphate receptor 4	0	1	1	2
Sphingosine 1-phosphate receptor 1	0	1	1	2
Sphingosine 1-phosphate receptor 3	0	1	1	2
Sphingosine 1-phosphate receptor 5	0	1	1	2
Orexin receptor type 1	0	0	0	1
Cathepsin B	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Cannabinoid receptor 1	0	2	2	8
Cannabinoid receptor 2	0	2	1	6
Cannabinoid receptor 2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
N-arachidonyl glycine receptor	0	1	0	1
G-protein coupled bile acid receptor 1	0	1	0	1
G-protein coupled receptor 55	0	0	1	1
Protein arginine N-methyltransferase 5	0	1	0	1
RmtA	0	1	0	1
Histone-arginine methyltransferase CARM1	0	1	0	1
Protein arginine N-methyltransferase 6	0	1	0	1
Protein arginine N-methyltransferase 1	0	2	0	2
Chain A, CES1 protein	0	1	0	1
DNA polymerase III, partial	1	0	0	1
interferon gamma precursor	0	0	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
D(4) dopamine receptor	0	2	0	2
Protein kinase C eta type	0	1	0	1
Substance-P receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Chain A, Prostatic Acid Phosphatase	0	1	0	1
Capsid protein	0	0	1	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Androgen receptor	0	0	1	1
Neuropeptide FF receptor 2	0	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	3	0	3
Collagenase 3	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	4	1	6
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
hemoglobin subunit beta	1	0	0	1
Apoptosis regulator Bcl-2	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Matrix metalloproteinase-14	0	2	0	2
Protein Rev	0	0	1	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Cytidine Deaminase	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Sodium/nucleoside cotransporter 2	0	2	0	2
Equilibrative nucleoside transporter 2	0	2	0	2
Equilibrative nucleoside transporter 1	0	2	0	2
Uridine-cytidine kinase 1	0	0	0	1
Solute carrier family 28 member 3	0	2	0	2
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Hsf1 protein	0	0	1	1
Farnesyl diphosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(4)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (1,810)

Protein Targets (1,975)

Osseous Paget's Disease

Synonyms(4)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (1,810)

Drugs Studied (323)

Protein Targets (1,975)