Page last updated: 2024-08-05 11:19:31

quaternary ammonium salt

Derivatives of ammonium compounds, (NH4(+))Y(-), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups.

ChEBI ID: 35273

Members (35)

MemberDefinitionRole
4-diphenylacetoxy-n-methylpiperidine methiodideA quaternary ammonium salt obtained by combining equimolar amounts of 4-diphenylacetoxy-N-methylpiperidine and iodomethane.4-DAMP methiodide
acetylcholine bromideThe bromide salt of acetylcholine.acetylcholine bromide
acetylcholine chlorideThe chloride salt of acetylcholine, and a parasympatomimetic drug.acetylcholine chloride
aclidinium bromideA quaternary ammonium salt that is the bromide salt of aclidinium. A muscarinic acetylcholine M3 receptor antagonist, for the long-term maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD).aclidinium bromide
ambenonium chlorideA symmetrical oxalamide-based bis-quaternary ammonium salt having ethyl and 2-chlorobenzyl groups attached to the nitrogens.ambenonium chloride
atracurium besylateThe bisbenzenesulfonate salt of atracurium.atracurium besylate
benzethonium chlorideA (synthetic) quaternary ammonium salt that is benzyldimethylamine in which the nitrogen is quaternised by a 2-{2-[p-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl group, with chloride as the counter-ion. An antiseptic and disinfectant, it is active against a broad spectrum of bacteria, fungi, moulds and viruses.benzethonium chloride
Betaine Aldehyde ChlorideBetaine Aldehyde Chloride
bethanechol chlorideThe chloride salt of bethanechol. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.bethanechol chloride
bretylium tosylateThe tosylate salt of bretylium. It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.bretylium tosylate
cetrimonium bromideThe organic bromide salt that is the bromide salt of cetyltrimethylammonium; one of the components of the topical antiseptic cetrimide.cetyltrimethylammonium bromide
choline chlorideA quaternary ammonium salt with choline cation and chloride anion.choline chloride
clomipramineA quaternary ammonium salt that is the tetrakis(N,N,N-trimethylmethammonium) salt of 5-({[4-(13-{4-[({3-carboxy-4-[(2,7-dichloro-6-hydroxy-3-oxo-3H-xanthen-9-yl)methyl]phenyl}carbonyl)amino]-2,5-bis(methyloxy)phenyl}-1,4,10-trioxa-7,13-diazacyclopentadecan-7-yl)-2-hydroxy-5-(methyloxy)phenyl]amino}carbonyl)-2-(2,7-dichloro-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid.sodium green
decamethoxinedecamethoxine
didecyldimethylammoniumDidecyldimethylammonium
dimethyldodecylbenzylammoniumThe organic bromide salt of benzododecinium. It is a cationic surfactant that has antispetic and disinfectant properties.benzododecinium bromide
dimethylphenylpiperazinium iodide1,1-dimethyl-4-phenylpiperazinium iodide
dioctyldimethyl ammonium chlorideDioctyldimethylammonium chloride
diphemanil methylsulfateThe alkene resulting from the formal Wittig olefination of benzophenone and 1,1-dimethyl-4-bromopiperidinium methylsulfate. A quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids, saliva and sweat, It is used topically in the treatment of hyperhidorsis (excessive sweating).diphemanil methylsulfate
diponium bromideDiponium bromide
dodecyltrimethylammonium bromideA quarternary ammonium cation having one dodecyl and three methyl substituents around the central nitrogen.dodecyltrimethylammonium bromide
echothiophate iodideThe iodide salt of ecothiopate. An irreversible acetylcholinesterase inhibitor, it is used an ocular antihypertensive in the treatment of open-angle glaucoma, particularly when other drugs have proved inadequate.ecothiopate iodide
edrophonium chlorideThe chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.edrophonium chloride
fm1 43FM 1-43 dye
glycopyrrolateA quaternary ammonium salt composed of 3-{[cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidin-1-ium and bromide ions in a 1:1 ratio.glycopyrronium bromide
hexafluoreniumhexafluronium
hexamethoniumHexamethonium
methacholine chloridemethacholine chloride
octotropine methylbromideA quaternary ammonium salt resulting from the reaction of the amino group of anisotropine with methyl bromide.anisotropine methylbromide
propyromazineAn organic bromide salt of propyromazine. It is a muscarinic antagonist which has antispasmodic potential.propyromazine bromide
rocuronium bromideThe organic bromide salt of a 5alpha androstane compound having 3alpha-hydroxy-, 17beta-acetoxy-, 2beta-morpholino- and 16beta-N-allyllyrrolidinium substituents.rocuronium bromide
tetraethylammonium chlorideA quarternary ammonium chloride salt in which the cation has four ethyl substituents around the central nitrogen.tetraethylammonium chloride
tiquizium bromideA organic bromide salt of tiquizium. It is an antispasmodic drug used for the treatment of convulsion and hypermobility in gastritis, gastric ulcer, duodenal ulcer, enteritis, irritable bowel syndrome, gallbladder disease, biliary tract disease and urolithiasis.tiquizium bromide
vecuronium bromideThe organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium substituents.vecuronium bromide
yo-pro 1An unsymmetrical C1 cyanine dye having 1,3-benzoxazol-2-yl and quinolinium-4-yl substituents.Yo-Pro-1

Research

Studies (12,779)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19903,779 (29.57)18.7374
1990's3,976 (31.11)18.2507
2000's2,839 (22.22)29.6817
2010's1,808 (14.15)24.3611
2020's377 (2.95)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials1,984 (14.35%)5.53%
Reviews444 (3.21%)6.00%
Case Studies621 (4.49%)4.05%
Observational33 (0.24%)0.25%
Other10,748 (77.72%)84.16%