Page last updated: 2024-09-27

Hallux Valgus

Lateral displacement of the great toe (HALLUX), producing deformity of the first METATARSOPHALANGEAL JOINT with callous, bursa, or BUNION formation over the bony prominence.

Synonyms(1)

Synonym
Hallux Valgus

Research Excerpts

Overview

ExcerptReference
"Hallux valgus is a pathological condition that is typically treated via the Lapidus procedure."( Actis, L; Bumgardner, CH; Li, X; Park, J; Ritz, J; Shen, VC, 2020)

Treatment

ExcerptReference
"The surgical treatment of hallux valgus deformity is connected with significant postoperative pain."( GÄ…dek, A; Liszka, H, 2015)
"For the treatment of hallux valgus commonly distal metatarsal osteotomies are performed."( Calderone, F; Claassen, L; Daniilidis, K; Ettinger, S; Plaass, C; Reifenrath, J; Sonnow, L; Stukenborg-Colsman, C; von Falck, C; Waizy, H; Weizbauer, A; Windhagen, H, 2018)

Research

Studies (166)

TimeframeStudies, This Condition (%)All Conditions %
pre-199035 (21.08)23.3326
1990's12 (7.23)12.5806
2000's30 (18.07)18.1394
2010's70 (42.17)28.8240
2020's19 (11.45)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0medium11
lactic acid0low20
iodine0low10
methanol0low10
nickel0low20
niacin0medium11
pyridoxine0low10
uric acid0low10
acetaminophen0medium54
cefuroxime0low10
celecoxib0medium21
clonidine0medium22
diclofenac0medium44
fentanyl0medium21
gentamicin0low10
ibuprofen0medium11
lidocaine0medium32
indomethacin0medium11
ketoprofen0medium11
ketorolac0medium11
khellin0medium11
meclizine0low10
mepivacaine0medium96
oxyphenbutazone0low10
rofecoxib0medium11
sulfamethoxazole0low10
tolmetin0medium11
trimethoprim0low10
prednisolone0low10
prednisone0low10
sucrose0low10
ethinyl estradiol0low10
norethindrone0low10
ampicillin0low10
isoprene0low20
thiophenes0medium22
ergotamine0low10
isoxazoles0medium11
dexamethasone 21-phosphate0medium11
methysergide0low10
betamethasone0medium11
fluorometholone0low10
dextropropoxyphene0low10
erythromycin0low20
zinc oxide0low10
silver0low10
titanium0medium182
silver nitrate0low10
calcium sulfate0low10
trolamine salicylate0low310
cetylpyridinium chloride anhydrous0low10
tramadol0medium32
sufentanil0medium11
fomesafen0low20
adenosine0low10
zoledronic acid0medium11
ketorolac tromethamine0medium11
nicotine0low10
levobupivacaine0medium76
imipenem, anhydrous0low10
valdecoxib0medium11
mk 06630medium41
n-(2,6-dimethylphenyl)-4-(((diethylamino)acetyl)amino)benzamide0low10
naproxen0medium11
nitinol0low10
fondaparinux0low10
ethisterone0low10
hydrocodone0medium11
naloxone0low10
oxycodone0medium54
morphine0medium54
silicon0low10
pregabalin0medium11
cefotaxime0low10
cilastatin0low10
boldenone undecylenate0low10
cilastatin, imipenem drug combination0low10
tetracycline0low10
minocycline0low20
salicylates0low10
warfarin0low10
rome0medium11
technetium tc 99m medronate0low10
guanine0low10

Protein Targets (992)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma210021
ATAD5 protein, partial7007
GLS protein7007
Microtubule-associated protein tau100010
Smad35005
aldehyde dehydrogenase 1 family, member A1150015
thyroid stimulating hormone receptor9009
nuclear receptor subfamily 1, group I, member 3130013
progesterone receptor190019
EWS/FLI fusion protein120012
retinoic acid nuclear receptor alpha variant 1200020
retinoid X nuclear receptor alpha150015
estrogen-related nuclear receptor alpha240024
estrogen nuclear receptor alpha370037
peroxisome proliferator activated receptor gamma130013
aryl hydrocarbon receptor120012
chromobox protein homolog 1120012
thyroid hormone receptor beta isoform 2180018
peripheral myelin protein 229009
cytochrome P450 3A4 isoform 1100010
Gamma-aminobutyric acid receptor subunit pi102012
ATP-binding cassette sub-family C member 3020020
Multidrug resistance-associated protein 4020020
Solute carrier family 22 member 60808
Carbonic anhydrase 120404
UDP-glucuronosyltransferase 1A90103
Bile salt export pump0303
Voltage-dependent calcium channel gamma-2 subunit120012
Bile salt export pump029029
Cytochrome P450 2B10102
Cytochrome P450 1A10001
Carbonic anhydrase 10909
Carbonic anhydrase 2010111
Myoglobin0101
Cytochrome P450 1A10214
Cytochrome P450 1A20405
Prostaglandin G/H synthase 1012013
Carbonic anhydrase 30303
Cytochrome P450 3A409110
Cytochrome P450 2D60505
Cytochrome P450 2C9 015117
Polyunsaturated fatty acid lipoxygenase ALOX150202
Gamma-aminobutyric acid receptor subunit beta-1102012
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta102012
Gamma-aminobutyric acid receptor subunit gamma-2102113
UDP-glucuronosyltransferase 1-60203
Glutamate receptor 2120012
Gamma-aminobutyric acid receptor subunit alpha-5102012
Gamma-aminobutyric acid receptor subunit alpha-3102012
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0305
Carbonic anhydrase 40303
Prostaglandin G/H synthase 1012013
Carbonic anhydrase 60303
Gamma-aminobutyric acid receptor subunit gamma-1102012
Gamma-aminobutyric acid receptor subunit alpha-2102012
Gamma-aminobutyric acid receptor subunit alpha-4102012
Gamma-aminobutyric acid receptor subunit gamma-3102012
Gamma-aminobutyric acid receptor subunit alpha-6102012
Carbonic anhydrase 5A, mitochondrial0303
Prostaglandin G/H synthase 2016220
Carbonic anhydrase 70303
Nuclear receptor ROR-gamma6006
Cytochrome P450 2J2010010
Gamma-aminobutyric acid receptor subunit alpha-1104115
Gamma-aminobutyric acid receptor subunit beta-3102012
Gamma-aminobutyric acid receptor subunit beta-2102113
Carbonic anhydrase 90819
GABA theta subunit102012
Canalicular multispecific organic anion transporter 1020020
Carbonic anhydrase 150303
Carbonic anhydrase 130202
Gamma-aminobutyric acid receptor subunit epsilon102012
Carbonic anhydrase 140404
Carbonic anhydrase 5B, mitochondrial0303
toxin B0001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE110011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein300030
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 47007
glucocorticoid receptor [Homo sapiens]190019
NPYLR7B0011
arylsulfatase A7007
IDH18008
Histone H2A.x8008
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 16006
flap endonuclease 17007
nuclear receptor ROR-gamma isoform 16006
survival motor neuron protein isoform d6006
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Rap guanine nucleotide exchange factor 32002
Purine nucleoside phosphorylase0303
Epidermal growth factor receptor0404
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30629
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A10516
Adenosine receptor A30101
Adenosine receptor A2a0326
Adenosine receptor A2b0012
Adenosine receptor A2b0123
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10326
Adenosine receptor A2a0426
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Chain A, Mutant Al2 6e7p9g0011
Chain A, Beta-lactamase6006
Chain A, 2-oxoglutarate Oxygenase6006
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Chain A, Cruzipain5005
Beta-lactamase 0103
acid sphingomyelinase2002
GLI family zinc finger 3210021
apical membrane antigen 1, AMA11001
farnesoid X nuclear receptor100010
Beta-lactamase 0103
Beta-lactamase 0003
Metallo-beta-lactamase type 20003
Metallo-beta-lactamase VIM-11 0003
euchromatic histone-lysine N-methyltransferase 2160016
Metallo-beta-lactamase VIM-20003
Beta-lactamase 0003
Metallo-beta-lactamase0003
Beta-lactamase 0103
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
DNA polymerase beta2002
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)5005
geminin160016
DNA polymerase kappa isoform 14004
60 kDa heat shock protein, mitochondrial0202
Beta-lactamase OXA-70001
Solute carrier family 15 member 10303
Solute carrier family 15 member 10101
Spike glycoprotein9009
10 kDa heat shock protein, mitochondrial0202
Angiopoietin-1 receptor0011
Beta-lactamase 0003
Beta-lactamase 0003
Beta-lactamase 0003
Solute carrier family 15 member 20202
Thiosulfate sulfurtransferase0202
Metallo-beta-lactamase VIM-130003
Efflux transporter 0001
Beta-lactamase 0003
Beta-lactamase Toho-10002
Beta-lactamase 0001
Class D beta-lactamase0001
60 kDa chaperonin 0202
Metallo-beta-lactamase0003
Solute carrier family 15 member 20202
Beta-lactamase 0003
Beta-lactamase 0002
10 kDa chaperonin 0202
Metallo-b-lactamase 0003
Carbapenem-hydrolyzing beta-lactamase KPC0003
Histamine H3 receptor0003
Beta-lactamase class B VIM-2 0003
Beta-lactamase VIM-1 0003
ATP-dependent phosphofructokinase5005
pregnane X receptor4004
cytochrome P450 family 3 subfamily A polypeptide 4180018
pregnane X nuclear receptor190019
vitamin D (1,25- dihydroxyvitamin D3) receptor150015
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a140014
nuclear receptor subfamily 1, group I, member 24004
thyroid hormone receptor beta isoform a7007
nuclear factor erythroid 2-related factor 2 isoform 26006
galanin receptor type 30101
nuclear factor erythroid 2-related factor 2 isoform 1140014
Glucocorticoid receptor014221
Glycine receptor subunit alpha-1014014
Glycine receptor subunit beta014014
Glycine receptor subunit alpha-2014014
Glycine receptor subunit alpha-3014014
ORF730011
Potassium channel subfamily K member 30404
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Potassium channel subfamily K member 90101
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0102
Metallo-beta-lactamase VIM-19 0002
Beta-lactamase 0001
Albumin06713
Beta-lactamase SHV-10001
Beta-lactamase SHV-10002
Beta-lactamase0002
Kappa-type opioid receptor07110
B2 metallo-beta-lactamase 0002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20002
Beta-lactamase 0001
Solute carrier family 22 member 60809
Solute carrier family 22 member 70203
Beta-lactamase 0001
BlaVIM-1 0002
Beta-lactamase 0002
Beta-lactamase 0001
Solute carrier family 22 member 80708
Beta-lactamase 0002
Solute carrier family 22 member 110102
Solute carrier family 22 member 80202
Solute carrier family 22 member 70102
Chain A, Carbonic anhydrase II0101
Carbonic anhydrase 0002
Carbonic anhydrase 0202
GTP-binding protein (rab7)0033
ras protein, partial0033
glp-1 receptor, partial6006
hypoxia-inducible factor 1 alpha subunit9009
SMAD family member 29009
USP1 protein, partial7007
PPM1D protein4004
SMAD family member 39009
TDP1 protein180018
caspase 7, apoptosis-related cysteine protease4004
estrogen receptor 2 (ER beta)100010
G130013
cytochrome P450 2D6140014
Carbonic anhydrase 0202
Carbonic anhydrase 0202
67.9K protein6006
peroxisome proliferator-activated receptor delta6006
Carbonic anhydrase0202
Rac1 protein0033
caspase-34004
cell division cycle 42 (GTP binding protein, 25kDa), partial0033
thyroid stimulating hormone receptor5005
activating transcription factor 69009
thyrotropin-releasing hormone receptor3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)110011
Caspase-72002
interferon gamma precursor0001
prostaglandin E2 receptor EP2 subtype0001
potassium voltage-gated channel subfamily H member 2 isoform d3003
caspase-32002
heat shock protein beta-16006
lamin isoform A-delta10140014
Prostaglandin E synthase0202
Histone deacetylase 30202
3-phosphoinositide-dependent protein kinase 10101
Prostaglandin G/H synthase 1 0506
Prostaglandin G/H synthase 2 0405
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Cytochrome c oxidase subunit 10202
Cytochrome c oxidase subunit 20101
Catechol O-methyltransferase0101
Cytochrome c oxidase subunit 20505
Interferon beta150015
HLA class I histocompatibility antigen, B alpha chain 130013
Cellular tumor antigen p53130013
Procathepsin L0202
Aldo-keto reductase family 1 member B10606
Seed linoleate 13S-lipoxygenase-10303
Neuronal acetylcholine receptor subunit alpha-435312
Polyunsaturated fatty acid 5-lipoxygenase0202
Quinolone resistance protein NorA0101
Neuronal acetylcholine receptor subunit beta-235312
Beta-3 adrenergic receptor0202
Alpha-1B adrenergic receptor0707
Calpain-2 catalytic subunit0202
Alpha-2B adrenergic receptor0819
5-hydroxytryptamine receptor 1A0707
D(1A) dopamine receptor0606
Prostaglandin G/H synthase 10404
Sodium-dependent noradrenaline transporter 0819
Cruzipain0202
Sodium/hydrogen exchanger 10101
Indoleamine 2,3-dioxygenase 10202
Sodium-dependent serotonin transporter0606
Sodium-dependent serotonin transporter0224
Delta-type opioid receptor010113
Delta-type opioid receptor011315
Mu-type opioid receptor012419
Bifunctional epoxide hydrolase 20303
Prostaglandin G/H synthase 2 0608
Carbonic anhydrase0202
Alpha-1A adrenergic receptor0718
Urotensin-2 receptor0101
Carbonic anhydrase0202
Histone deacetylase 40202
Ras-related protein Rab-2A0033
D(2) dopamine receptor0202
Prostaglandin G/H synthase 2011011
Carbonic anhydrase 0202
Mu-type opioid receptor015116
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20202
Sodium-dependent dopamine transporter 0404
Prostaglandin G/H synthase 20506
Histone deacetylase 10202
Mitogen-activated protein kinase 140202
Carbonic anhydrase, alpha family 0202
Carbonic anhydrase 0202
Carbonic anhydrase0202
Carbonic anhydrase0202
Carbonic anhydrase 0202
Sigma intracellular receptor 20202
Delta carbonic anhydrase0202
Prostaglandin G/H synthase 1 0608
Carbonic anhydrase 0202
Prostaglandin G/H synthase 10101
Carbonic anhydrase 130202
Cyclooxygenase-2 0101
Histone deacetylase 70202
Rap guanine nucleotide exchange factor 41001
Inositol hexakisphosphate kinase 1130013
Histone deacetylase 20202
Carbonic anhydrase 40505
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
ATPase family AAA domain-containing protein 55005
Ataxin-26006
Histone deacetylase 80202
P2Y purinoceptor 120303
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
cytochrome P450 2C9, partial130013
Chain A, Ferritin light chain4004
acetylcholinesterase8008
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
vitamin D3 receptor isoform VDRA5005
Caspase-20011
Inositol monophosphatase 16006
phosphopantetheinyl transferase3003
Beta-2 adrenergic receptor0101
Beta-1 adrenergic receptor0101
Dipeptidase 10101
Beta-3 adrenergic receptor0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
Beta-1 adrenergic receptor 0011
Alpha-1B adrenergic receptor 0011
cytochrome P450 2D6 isoform 14004
cytochrome P450 2C19 precursor3003
cytochrome P450 2C9 precursor2002
muscarinic acetylcholine receptor M13003
Membrane primary amine oxidase 0101
Solute carrier family 22 member 1 011013
5-hydroxytryptamine receptor 3A0011
Solute carrier family 22 member 30202
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0628
Alpha-1A adrenergic receptor0011
Alpha-2C adrenergic receptor0415
D0101
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0202
Amine oxidase [flavin-containing] A0303
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0303
Alpha-1D adrenergic receptor0415
D(1B) dopamine receptor0101
Amine oxidase [flavin-containing] B0202
5-hydroxytryptamine receptor 1B0606
Alpha-2B adrenergic receptor0001
D(4) dopamine receptor0101
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0112
Histamine H2 receptor2002
5-hydroxytryptamine receptor 70303
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Alpha-2A adrenergic receptor0101
Nischarin0202
Solute carrier family 22 member 10202
Multidrug and toxin extrusion protein 10707
Nischarin0101
GALC protein2002
Cytochrome P450 2A60314
Cytochrome P450 2A50202
Mas-related G-protein coupled receptor member X20033
Aldo-keto reductase family 1 member B100101
Transient receptor potential cation channel subfamily A member 10022
Dihydrofolate reductase0505
Fatty acid-binding protein, liver0404
Transthyretin0013
Interleukin-80303
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Fatty acid-binding protein, intestinal0415
Aldo-keto reductase family 1 member B10303
UDP-glucuronosyltransferase 2B70104
UDP-glucuronosyltransferase 1A40101
Sodium- and chloride-dependent GABA transporter 10303
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
UDP-glucuronosyltransferase 1A30004
UDP-glucuronosyltransferase 2B10 0101
Sodium- and chloride-dependent betaine transporter0303
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Adenylate cyclase 0101
5-hydroxytryptamine receptor 40404
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
ATP-dependent translocase ABCB10404
Beta-2 adrenergic receptor0202
ATP-dependent translocase ABCB10707
Beta-1 adrenergic receptor0202
D(2) dopamine receptor0505
ATP-dependent translocase ABCB10404
Sodium-dependent dopamine transporter0303
Thromboxane-A synthase 0202
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
D(3) dopamine receptor0505
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 60404
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0101
serine/threonine-protein kinase PLK12002
streptokinase A precursor0011
Motilin receptor0112
30S ribosomal protein S60213
30S ribosomal protein S70213
50S ribosomal protein L150213
60 kDa chaperonin0101
50S ribosomal protein L100213
50S ribosomal protein L110213
50S ribosomal protein L7/L120213
50S ribosomal protein L190213
50S ribosomal protein L10213
50S ribosomal protein L200213
50S ribosomal protein L270213
50S ribosomal protein L280213
50S ribosomal protein L290213
50S ribosomal protein L310213
50S ribosomal protein L31 type B0213
50S ribosomal protein L320213
50S ribosomal protein L330213
50S ribosomal protein L340213
50S ribosomal protein L350213
50S ribosomal protein L360213
30S ribosomal protein S100213
30S ribosomal protein S110213
30S ribosomal protein S120213
30S ribosomal protein S130213
30S ribosomal protein S160213
30S ribosomal protein S180213
30S ribosomal protein S190213
30S ribosomal protein S200213
30S ribosomal protein S20213
30S ribosomal protein S30213
30S ribosomal protein S40213
30S ribosomal protein S50213
30S ribosomal protein S80213
30S ribosomal protein S90213
50S ribosomal protein L130213
50S ribosomal protein L140213
50S ribosomal protein L160213
50S ribosomal protein L230213
30S ribosomal protein S150213
50S ribosomal protein L170213
50S ribosomal protein L210213
50S ribosomal protein L300213
50S ribosomal protein L60213
30S ribosomal protein S140213
30S ribosomal protein S170213
30S ribosomal protein S10213
50S ribosomal protein L180213
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0101
50S ribosomal protein L20213
50S ribosomal protein L30213
50S ribosomal protein L240213
50S ribosomal protein L40213
50S ribosomal protein L220213
50S ribosomal protein L50213
30S ribosomal protein S210213
50S ribosomal protein L250213
Potassium voltage-gated channel subfamily H member 2011011
Cytochrome P450 1B10202
Lanosterol 14-alpha demethylase0101
50S ribosomal protein L36 20213
Luciferase120012
interleukin 86006
Fumarate hydratase5005
polyprotein5005
lysosomal alpha-glucosidase preproprotein3003
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Vpr2002
Solute carrier family 22 member 20101
Estrogen receptor0617
Sex hormone-binding globulin0033
Androgen receptor0909
Cytochrome P450 2B60101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Mu-type opioid receptor013823
Kappa-type opioid receptor011417
Sulfotransferase 1A10214
Aldehyde oxidase0101
TAR DNA-binding protein 438008
Nuclear receptor subfamily 1 group I member 3 0101
Multidrug and toxin extrusion protein 20101
Estrogen receptor beta0314
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Polyphenol oxidase 20202
Guanine nucleotide-binding protein G5005
Nuclear receptor subfamily 1 group I member 20022
D(4) dopamine receptor0101
Kappa-type opioid receptor06310
Histamine H1 receptor0101
Delta-type opioid receptor08313
Mu-type opioid receptor05210
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10516
Sigma non-opioid intracellular receptor 10213
huntingtin isoform 23003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Nuclear receptor subfamily 1 group I member 20011
Coagulation factor X0101
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
thioredoxin reductase6006
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B4004
Bloom syndrome protein isoform 14004
D(1A) dopamine receptor3003
transcriptional regulator ERG isoform 32002
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
histone acetyltransferase KAT2A isoform 14004
neuropeptide S receptor isoform A3003
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Gamma-aminobutyric acid receptor subunit alpha-60112
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0011
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Gamma-aminobutyric acid type B receptor subunit 10011
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid type B receptor subunit 10101
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0102
NFKB1 protein, partial2002
nonstructural protein 11001
importin subunit beta-1 isoform 12002
snurportin-12002
muscleblind-like protein 1 isoform 12002
Acid-sensing ion channel 30101
Solute carrier organic anion transporter family member 1A40101
Albumin0102
Albumin0022
Cholinesterase0101
Polyunsaturated fatty acid 5-lipoxygenase0307
Acetylcholinesterase0101
Caspase-10405
Substance-P receptor0202
Aldo-keto reductase family 1 member C30404
Caspase-30404
Solute carrier organic anion transporter family member 1A10101
Caspase-40404
4-aminobutyrate aminotransferase, mitochondrial0101
Caspase-50404
Caspase-90404
Acid-sensing ion channel 10101
Fatty-acid amide hydrolase 10101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Dehydrogenase/reductase SDR family member 90101
Beta-lactamase 0001
Beta-lactamase0001
Metallo-beta-lactamase type 20001
Beta-lactamase TEM0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase IMP-1 0001
Beta-lactamase 0001
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
glucocerebrosidase1001
Parkin2002
peripheral myelin protein 22 isoform 12002
ras-related protein Rab-9A3003
serine/threonine-protein kinase mTOR isoform 11001
M-phase phosphoprotein 81001
Prostaglandin-H2 D-isomerase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Phospholipase A2, major isoenzyme0101
Androgen receptor0213
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40202
Serum paraoxonase/arylesterase 10202
Nitric oxide synthase, inducible0101
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
C-X-C chemokine receptor type 30202
Aldo-keto reductase family 1 member C2 0202
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30202
Lactoylglutathione lyase0303
Aldo-keto reductase family 1 member C10202
Uracil nucleotide/cysteinyl leukotriene receptor0101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Dehydrogenase/reductase SDR family member 90101
Solute carrier organic anion transporter family member 1B30202
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10202
histone deacetylase 9 isoform 34004
cellular tumor antigen p53 isoform a3003
Integrin beta-32002
Integrin alpha-IIb2002
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
NPC intracellular cholesterol transporter 1 precursor1001
Cell division control protein 42 homolog0101
Ras-related C3 botulinum toxin substrate 10101
Serine/threonine-protein kinase PAK 10101
GTP-binding nuclear protein Ran isoform 11001
Cytochrome P450 2C190101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
Liver carboxylesterase 10001
Kappa-type opioid receptor0428
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain E, Fibrin beta chain0101
Chain A, JmjC domain-containing histone demethylation protein 3A3003
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase3003
hypothetical protein, conserved2002
isocitrate dehydrogenase 1, partial1001
luciferase1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain1001
Amyloid-beta precursor protein0202
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Alpha-synuclein1102
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
endonuclease IV2002
dopamine D1 receptor2002
DNA polymerase III, partial1001
alpha-galactosidase1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Stromelysin-10202
Matrilysin0101
Multidrug transporter MdfA0202
Matrix metalloproteinase-90202
Protein mono-ADP-ribosyltransferase PARP150101
Protein-arginine deiminase type-40505
Opioid receptor, delta 1b 0101
Acetylcholinesterase0202
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Muscarinic acetylcholine receptor M10303
Muscarinic acetylcholine receptor M30303
Muscarinic acetylcholine receptor M40404
Muscarinic acetylcholine receptor M50303
Muscarinic acetylcholine receptor M20303
Translocator protein0112
Histidine decarboxylase0022
Proteinase-activated receptor 10224
Nociceptin receptor0101
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0202
Mu-type opioid receptor0101
UDP-glucuronosyltransferase 1A80001
Hormone-sensitive lipase0101
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
5-hydroxytryptamine receptor 3E0101
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3B0101
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-30225
Acetylcholine receptor subunit gamma0213
Neuronal acetylcholine receptor subunit alpha-40101
Acetylcholine receptor subunit beta0213
Neuronal acetylcholine receptor subunit alpha-20225
Neuronal acetylcholine receptor subunit beta-30225
Neuronal acetylcholine receptor subunit beta-40225
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-50225
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Muscarinic acetylcholine receptor M40101
Neuronal acetylcholine receptor subunit alpha-30213
Neuronal acetylcholine receptor subunit alpha-70224
Neuronal acetylcholine receptor subunit alpha-60225
Neuronal acetylcholine receptor subunit alpha-90225
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3A0101
Neuronal acetylcholine receptor subunit alpha-70202
Acetylcholine-binding protein0112
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Neuronal acetylcholine receptor subunit alpha-70225
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
5-hydroxytryptamine receptor 3D0101
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-100225
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Transporter0113
Estrogen receptor0011
Progesterone receptor0427
Estrogen receptor beta0011
Nrf21001
Microphthalmia-associated transcription factor0001
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
caspase recruitment domain family, member 150101
glucose-6-phosphate 1-dehydrogenase isoform b0101
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Beta lactamase (plasmid)0101
Nuclear receptor subfamily 4 group A member 20101
luciferase0001
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Voltage-dependent calcium channel subunit alpha-2/delta-10102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Pyridoxal kinase0001
inositol monophosphatase 11001
Prostaglandin G/H synthase 20101
Cytochrome c oxidase subunit 10101
Transporter0101
Sodium-dependent serotonin transporter0101
Sphingosine kinase 20202
Sphingosine kinase 10101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
5-hydroxytryptamine receptor 2A0202
Dihydrofolate reductase0304
Endothelin-1 receptor0101
Protease 0213
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
heat shock protein HSP 90-alpha isoform 20101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
Tetracycline resistance protein, class B0001
Muscarinic acetylcholine receptor M20101
72 kDa type IV collagenase0202
Neutrophil collagenase0202
Collagenase 30101
Cannabinoid receptor 10101
Integrase 0101
P2Y purinoceptor 120101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
lethal factor (plasmid)1001
Dihydrofolate reductase 0102
Dihydrofolate reductase0101
Dihydrofolate reductase 0101
Dihydrofolate reductase0202
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
NH(3)-dependent NAD(+) synthetase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Dihydrofolate reductase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2B0101
Metabotropic glutamate receptor 50101
Dihydrofolate reductase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Chain A, Carbonic anhydrase II0101
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
Butyrophilin subfamily 3 member A10012
Geranylgeranyl pyrophosphate synthase0203
Farnesyl pyrophosphate synthase0202
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Farnesyl pyrophosphate synthase 0202
Geranylgeranyl pyrophosphate synthase0202
Farnesyl pyrophosphate synthase 0101
H0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]