Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
| Member | Definition | Class |
|---|
| 2-allylphenol | A member of the class of phenols that is phenol carrying an allyl group at position 2. | 2-allylphenol |
| 2-chloro-n-(4-chlorobiphenyl-2-yl)nicotinamide | A pyridinecarboxamide obtained by formal condensation of the carboxy group of 2-chloronicotinic acid with the amino group of 4'-chlorobiphenyl-2-amine. A fungicide active against a broad range of fungal pathogens including Botrytis spp., Alternaria spp. and Sclerotinia spp. for use on a wide range of crops including fruit, vegetables and ornamentals. | boscalid |
| 2-n-octyl-4-isothiazolin-3-one | A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It is no longer approved for use within the European Union. | octhilinone |
| 2-phenylphenol | A member of the class of hydroxybiphenyls that is biphenyl substituted by a hydroxy group at position 2. It is generally used as a post-harvest fungicide for citrus fruits. | biphenyl-2-ol |
| 3-iodo-2-propynylbutylcarbamate | A carbamate ester that is carbamic acid in which the nitrogen has been substituted by a butyl group and in which the hydrogen of the carboxy group is replaced by a 1-iodoprop-2-yn-3-yl group. A fungicide, it is used as a preservative and sapstain control chemical in wood products and as a preservative in adhesives, paints, latex paper coating, plastic, water-based inks, metal working fluids, textiles, and numerous consumer products. | 3-iodoprop-2-yn-1-yl butylcarbamate |
| 4,5,6,7-tetrachlorophthalide | A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one in which all or the hydrogens attached to the benzene ring are replaced by chlorines. A fungicide used for the control of rice blast, it is not approved for use within the European Union. | 4,5,6,7-tetrachloro-2-benzofuran-1(3H)-one |
| ametoctradin | A member of the class of triazolopyrimidines that is [1,2,4]triazolo[1,5-a]pyrimidin-7-amine carrying additional ethyl and octyl substituents at positions 5 and 6 respectively. A fungicide for the control of late blight and downey mildew on potatoes and other crops including vines. | ametoctradin |
| azaconazole | A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2,4-dichlorophenyl and 1,2,4-triazol-1-ylmethyl groups. A fungicide used mainly in ornamental crops to control canker and other diseases. Azaconazole is moderately toxic to mammals but is not expected to bioaccumulate. It is moderately toxic to birds, fish and aquatic invertebrates. | azaconazole |
| azoxystrobin | An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture. | azoxystrobin |
| benomyl | A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. | benomyl |
| bithionol | An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders. | bithionol |
| bupirimate | A member of the class of aminopyrimidines that is 2-ethylaminopyrimidine carrying methyl, butyl and dimethylaminosulfooxy substituents at posiitons 4, 5 and 6 respectively. | bupirimate |
| captafol | A dicarboximide that captan in which the trichloromethyl group is replaced by a 1,1,2,2-tetrachloroethyl group. A broad-spectrum fungicide used to control diseases in fruit and potatoes, it is no longer approved for use in the European Community. | captafol |
| captan | A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops. | captan |
| carbendazim | A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables. | carbendazim |
| carboxin | An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment. | carboxin |
| carpropamid | A cyclopropylcarboxamide obtained by formal condensation of the carboxy group of 2,2-dichloro-1-ethyl-3-methylcyclopropanecarboxylic acid with the amino group of 1-(4-chlorophenyl)ethylamine. A rice fungicide with specific action against Pyricularia oryzae. It is not highly toxic to mammals but shows a moderate level of toxicity to birds, fish and earthworms. | carpropamid |
| chloroneb | A dimethoxybenzene that is p-dimethoxybenzene which is substituted by chlorines at positions 2 and 5. A fungicide formerly used as a seed treatment, it is not approved for use in the European Union. | chloroneb |
| chloropicrin | A C-nitro compound that is nitromethane in which all three hydrogens are replaced by chlorines. It is a severe irritant, and can cause immediate, severe inflammation of the eyes, nose and throat, and significant injuries to the upper and lower respiratory tract. Formerly stockpiled as a chemical warfare agent, it has been widely used in the US as a soil fumigant, particularly for strawberry crops. It is not approved for use within the European Union. | chloropicrin |
| cyazofamid | A member of the class of imidazoles carrying dimethylsulfamyl, cyano, chloro and 4-tolyl substituents at positions 1, 2, 4 and 5 respectively. A fungicide used mainly for controlling Oomycete and Plasmodiophora diseases on potatoes and tomatoes. It is a skin and eye irritant and is moderately toxic to birds, most aquatic organisms, honeybees and earthworms. | cyazofamid |
| cyprodinil | A member of the class of aminopyrimidine that is N-phenylpyrimidin-2-amine carrying additional cyclopropyl and methyl substituents at positions 4 and 6 respectively. A broad spectrum fungicide used to control a range of pathogens including Tapesia yallundae, Botrytis spp., Alternaria spp. and Rhynchospium secalis. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds as well as most aquatic organisms and earthworms, but it is not considered toxic to honeybees. | cyprodinil |
| dazomet | A dithiocarbamic ester that is 1,3,5-thiadiazinane with a thione moiety at position 2 and in which the hydrogens attached to the nitrogens are replaced by methyl groups. A fungicide, herbicide and nematicide, it is used prior to sowing or planting for the control of soil fungi, nematodes, bacteria and germinating weeds, and as fumigant for poultry litter and eggs to control Salmonella. It is a non-ozone-depleting alternative to methyl bromide. | dazomet |
| dichlofluanid | A member of the class of sulfamides that is sulfamide in which the hydrogens attached to one of the nitrogens are replaced by methyl groups, while those attached to the other nitrogen are replaced by a phenyl and a [dichloro(fluoro)methyl]sulfanediyl group. A fungicide introduced in 1965 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union. | dichlofluanid |
| dicloran | A nitroaniline that is 4-nitroaniline in which the hydrogens at positions 2 and 6 are replaced by chlorines. An agricultural fungicide, it is not approved for use in the European Union. | 2,6-dichloro-4-nitroaniline |
| diethofencarb | A carbamate ester that is the isopropyl ester of (3,4-diethoxyphenyl)carbamic acid. A fungicide with strong activity against Botrytis cinerea and benzimidazole-resistant strains of Botryis spp. | diethofencarb |
| difenoconazole | A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms. | difenoconazole |
| dimethomorph | A mixture of (E)- and (Z)-dimethomorph in an unspecified ratio. It is used as a systemic fungicide used on vines, potatoes, and greenhouse crops; only the Z isomer has fungicidal activity. | dimethomorph |
| diphenyl | A benzenoid aromatic compound that consists of two benzene rings connected by a single covalent bond. Biphenyl occurs naturally in coal tar, crude oil, and natural gas. Formerly used as a fungicide for citrus crops. | biphenyl |
| diphenylamine | An aromatic amine containing two phenyl substituents. It has been used as a fungicide for the treatment of superficial scald in apples and pears, but is no longer approved for this purpose within the European Union. | diphenylamine |
| dithianone | A naphthodithiin that is 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiin which is substituted by nitrile groups at positions 2 and 3. It is a broad spectrum fungicide used to control scab, downy mildew, rust, and leaf spot in the commercial growing of grapes and other fruit, citrus, coffee, and vegetables. | dithianon |
| dodine | An acetate salt resulting from the reaction of equimolar amounts of 1-dodecylguanidine and acetic acid. It is used as a fungicide to control black spot and foliar diseases on apples, pears, peaches, nectarines and strawberries. | 1-dodecylguanidine acetate |
| dyrene | A member of the class of triazenes that is dichlorotriazene in which the hydrogen is replaced by an o-chloroanilino group. A fungicide formerly used to control leaf spots and downy mildew, it is no longer approved for use within the European Union. | anilazine |
| edifenphos | An organic thiophosphate that is the O-ethyl-S,S-diphenyl ester of phosphorodithioic acid. Used to control a variety of fungal diseases on rice including blast, ear blight and stem rot. Edifenphos is moderately toxic to mammals and fish but poses more of a risk to aquatic invertebrates. | edifenphos |
| ethirimol | An aminopyrimidine that is 2-ethylaminopyrimidin-4-one carrying butyl and methyl substituents at positions 5 and 6 respectively. A fungicide first marketed in 1970 and used as a seed treatment for diseaases such as damping-off, it is not licensed for use within the European Union. | ethirimol |
| ethoxyquin | A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6. | ethoxyquin |
| etridiazol | A member of the class of thiadiazoles that is 1,2,4-thiadiazole which is substituted at positions 3 and 5 by trichloromethyl and ethoxy groups, respectively. A fungicide, it has been used particularly for the control of Phytophthora and Pythium species in soils. | etridiazole |
| fenamidone | A member of the class of imidazolones that is 3,5-dihydroimidazol-4-one substituted at position 2 by a methylthiogroup, at position 3 by an anilino group and at position 5 by phenyl and methyl groups (the S-enantiomer). A fungicide effective against Oomycete diseases such as downy mildew and certain leaf spot diseases. | fenamidone |
| fenpiclonil | A member of the class of pyrroles carrying cyano and 2,3-dichlorophenyl substituents at positions 3 and 4 respectively. A fungicide used mainly to control seed-borne pathogens in cereal crops. | fenpiclonil |
| fluazinam | A member of the class of aminopyridines that is 2-amino-5-(trifluoromethyl)pyridine in which one of the amino hydrogens is replaced by a 3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl group. A fungicide used to control grey mould, downy mildew and other fungal pathogens. | fluazinam |
| fludioxonil | A member of the class of benzodioxoles that is 2,2-difluoro-1,3-benzodioxole substituted at position 4 by a 3-cyanopyrrol-4-yl group. A fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria. | fludioxonil |
| fluopicolide | A member of the class of benzamides obtained by formal condensation of the carboxy group of 2,6-dichlorobenzoic acid with the amino group of [3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylamine. A fungicide used for the control of a range of diseases including downy mildew and blight. | fluopicolide |
| fluoxastrobin | An oxime O-ether that is the O-methyl oxime of (2-{[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxy}phenyl)(5,6-dihydro-1,4,2-dioxazin-3-yl)methanone. A fungicide used for disease control of potatoes and a wide range of vegetables. | fluoxastrobin |
| fluquinconazole | A member of the class of quinazolines that is 6-fluoroquinazolin-4-one carrying additional 1,2,4-triazol-1-yl and 2,4-dichlorophenyl substituents at positions 2 and 3 respectively. A fungicide used to control Ascomycetes, Deuteromycetes and Basidiomycetes spp. on cereals, beets and fruit. | fluquinconazole |
| flusilazole | An organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by p-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1H-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops. | flusilazole |
| flutolanil | A member of the class of benzamides, obtained by formal condensation of the carboxy group of 2-(trifluoromethyl)benzoic acid with the amino group of 3-(ispropyloxy)aniline. A fungicide used to control a range of pathogens especially Rhizoctonia spp. on rice, turf and other crops. | flutolanil |
| fluxapyroxad | An aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 3',4',5'-trifluorobiphenyl-2-amine. Used to control a number of cereal fungal pathogens including those belonging to the Ascomycetes, Basidiomycetes and Zygomycetes families. | fluxapyroxad |
| folpet | A member of the class of phthalimides that is phthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethylthio group. An agricultural fungicide, it has been used to control mildew, leaf spot, and other diseases in crops sice the 1950s. | folpet |
| fuberidazole | A ring assembly consisting of benzimidazole substituted at position 2 by a 2-furyl group. A fungicide used as a seed treatment to control Fusarium spp. in cereals. | fuberidazole |
| guazatine | A member of the class of guanidines that is dioctylamine in which a hydrogen from each of the terminal methyl groups is replaced by a guanidino group. Once used as a fungicidal seed dressing, it is no longer approved for use in the European Union. | iminoctadine |
| hexachlorobenzene | A member of the class of chlorobenzenes that is benzene in which all of the hydrogens are replaced by chlorines. An agricultural fungicide introduced in the mid-1940s and formerly used as a seed treatment, its use has been banned since 1984 under the Stockholm Convention on Persistent Organic Pollutants. | hexachlorobenzene |
| hexachlorophene | An organochlorine compound that is diphenylmethane in which each of the phenyl groups is substituted by chlorines at positions 2, 3, and 5, and by a hydroxy group at position 6. An antiseptic that is effective against Gram-positive organisms, it is used in soaps and creams for the treatment of various skin disorders. It is also used in agriculture as an acaricide and fungicide, but is not approved for such use within the European Union. | hexachlorophene |
| hymexazol | A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals. | hymexazol |
| iprodione | An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide. | iprodione |
| isoprothiolane | A malonate ester that is diisopropyl malonate in which the two methylene hydrogens at position 2 are replaced by a 1,3-dithiolan-2-ylidene group. An insecticide and fungicide used to control a range of diseases including Pyricularia oryzae, Helminthosporium sigmoideum and Fusarium nivale. | isoprothiolane |
| kresoxim-methyl | A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops. | kresoxim-methyl |
| liquid crystal polymer | A member of the class of oxolanes carrying 1,2,4-triazol-ylmethyl and 2,4-dichlorophenyl substituents at position 2 as well as a bromo substituent at position 4. A foliar applied conazole fungicide for a range of crops including cereals, fruit, vegetables and vines. | bromuconazole |
| mepanipyrim | A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying additional methyl and 1-propynyl substituents at positions 4 and 6 respectively. A fungicide used to control a wide range of diseases including grey mould on strawberries, tomatoes and cucumabers, and scab on apples and pears. | mepanipyrim |
| metconazole | A member of the class of cyclopentanols carrying 1,2,4-triazol-1-ylmethyl and 4-chlorobenzyl and geminal dimethyl substituents at positions 1, 2 and 5 respectively. Used to control a range of fungal infections including alternaria, rusts, fusarium and septoria diseases. | metconazole |
| metrafenone | A member of the class of benzophenones that is benzophenone in which one of the phenyl groups is substituted by methoxy groups at positions 2, 3, and 4 and by a methyl group at position 6, while the other is substituted at positions 2, 3, and 6 by methyl, bromine, and methoxy groups, respectively. A fungicide with protectant and curative properties, it is used for the control of powdery mildew in cereals and grape vines. | metrafenone |
| n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide | An aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol. | fenhexamid |
| n-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide | A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 4-methyl-1,2,3-thiadiazole-5-carboxylic acid with the amino group of 3-chloro-4-methylaniline. It is a fungicide used particularly for the control of fungal diseases in rice. | tiadinil |
| n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide | A member of the class of sulfamides that is dichlofluanid in which the hydrogen at the para position of the phenyl group is replaced by a methyl group. A fungicide first marketed in 1971 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union. | tolylfluanid |
| nabam | A dithiocarbamate salt that is the disodium salt of ethylenebis(dithiocarbamic acid). A fungicide, algicide and bactericide used on various crops including on cotton, capsicums, onions and rice crops, it is considered to be a carcinogen, so is not licensed for use within the European Union. Mixing nabam with zinc sulfate affords the fungicide zineb. | nabam |
| natamycin | A macrolide antibiotic that has formula C33H47NO13, produced by several Streptomyces species including Streptomyces natalensis. It exhibits broad spectrum antifungal activity and used in eye drops, and as a food preservative, and also as a postharvest biofungicide for citrus and other fruit crops. | natamycin |
| o,o-diisopropyl-s-benzylthiophosphate | An organic thiophosphate that is the S-benzyl O,O-diisopropyl ester of phosphorothioic acid. Used as a rice fungicide to control leaf and ear blast, stem rot and sheath blight. | iprobenfos |
| oryzemate | A member of the class of 1,2-benzothiazoles that is 1,2-benzothiazole 1,1-dioxide substituted at position 3 by an allyloxy group. A fungicide used to control rice blast. | probenazole |
| oxycarboxin | An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-4,4-dioxo-1,4-oxathiine-3-carboxylic acid. A fungicide for the control of rust diseases on ornamentals, cereals and nursery trees as well as fairy rings on turf. | oxycarboxin |
| oxyquinoline | A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes. | quinolin-8-ol |
| pencycuron | A member of the class of phenylureas that is urea which is substituted by p-chlorobenzyl and cyclopentyl groups at position 1 and a phenyl group at position 3. A fungicide used to control diseases caused by Rhizoctonia solani and Pellicularia spp. It is not highly toxic to mammals but is moderately toxic to birds, most aquatic organisms, honeybees and earthworms. | pencycuron |
| phentin acetate | An organotin compound that is the O-acetyl derivative of triphenyltin hydroxide. A fungicide used to control blights on potatoes, leaf spot diseases on sugar beet and anthracnose on beans. | fentin acetate |
| picoxystrobin | An enoate ester that is the methyl ester of (2E)-3-methoxy-2-[2-({[6-(trifluoromethyl)pyridin-2-yl]oxy}methyl)phenyl]prop-2-enoic acid. A cereal fungicide used to control a wide range of diseases including brown rust, tan spot, powdery mildew and net blotch. | picoxystrobin |
| potassium bicarbonate | A potassium salt that is the monopotassium salt of carbonic acid. It has fungicidal properties and is used in organic farming for the control of powdery mildew and apple scab. | potassium hydrogencarbonate |
| prochloraz | A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables. | prochloraz |
| propamocarb | A carbamate ester that is the propyl ester of 3-(dimethylamino)propylcarbamic acid. It is a systemic fungicide, used (normally as the hydrochloride salt) for the control of soil, root and leaf diseases caused by oomycetes, particularly Phytophthora and Pythium species. | propamocarb |
| propiconazole | The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds. | propiconazole |
| propineb | A polymeric complex of zinc with the propylene 1,2-bis(dithiocarbamate) anionic ligand. A fungicide, it is used to control a wide range of fungal diseases, including downy mildew, brown rot, black rot, red fire, leaf spot, and blight in crops such as grapes, tomatoes, potatoes, berries, citrus, rice and tea. | propineb |
| pyrachlostrobin | A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres. | pyraclostrobin |
| pyrazophos | A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A profungicide (by hydrolysis of the thionophosphate group to afford the corresponding 2-hydroxypyrazolopyrimidine fungicide), it is used to control Erysiphe, Helminthosporium and Rhynchospium in cereals. | pyrazophos |
| pyrimethanil | A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine. | pyrimethanil |
| quinoxyfen | A member of the class of quinolines carrying two chloro substituents at positions 5 and 7 together with a 4-fluorophenoxy substituent at position 4. A fungicide used mainly to control powdery mildew in cereals. | quinoxyfen |
| quintozene | A C-nitro compound that is nitrobenzene in which every hydrogen has been replaced by a chlorine. A fungicide used on a variety of crops, including cotton, rice and seed grains, it is no longer approved for use within the European Union. | pentachloronitrobenzene |
| s-methyl benzo(1,2,3)thiadiazole-7-carbothioate | A benzothiadiazole that is the S-methyl thioester derivative of acibenzolar. A profungicide (by hydrolysis of the thioester group to give the corresponding carboxylic acid), it is used as a fungicide and plant activator on a variety of crops, including cotton, chili peppers, lettuce, onions, spinach, tobacco, and tomatoes. | acibenzolar-S-methyl |
| spiroxamine | The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powdery mildew in the production of cereals, bananas and grapes. | spiroxamine |
| streptomycin | A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class | streptomycin |
| tecnazene | A C-nitro compound that is nitrobenzene in which the four hydrogens located ortho- and para- to the nitro group have been replaced by chlorines. A fungicide used to control dry rot, it is no longer approved for use within the European Union. | tecnazene |
| tetrachloroisophthalonitrile | A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops. | chlorothalonil |
| thiabendazole | A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium. | thiabendazole |
| thifluzamide | An aromatic amide obtained by formal condensation of the carboxy group of 2-methyl-4-(trifluoromethyl)thiazole-5-carboxylic acid with the amino group of 2,6-dibromo-4-(trifluoromethoxy)aniline. Used to control Rhizoctonia spp. diseases on rice, potatoes, maize, grass and other crops. | thifluzamide |
| thiophanate | A member of the class of thioureas that is the dimethyl ester of (1,2-phenylenedicarbamothioyl)biscarbamic acid. A fungicide effective against a broad spectrum of diseases in fruit, vegetables, turf and other crops including eyespot, scab, powdery mildew and grey mould. | thiophanate-methyl |
| thiram | An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment. | thiram |
| tolclofos-methyl | An organic thiophosphate that is 2,6-dichloro-4-methylphenol in which the hydrogen of the hydroxy group group has been replaced by a dimethoxyphosphorothioyl group. Tolclofos-methyl is a phospholipid biosynthesis inhibitor and fungicide that is used for controlling soil-borne diseases caused by Typhula incarnata, Corticium rolfsii, Typhula ishikariensis, and Rhizoctonia solani. | tolclofos-methyl |
| triadimenol | A member of the class of triazoles that is 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butane-1,2-diol substituted at position O1 by a 4-chlorophenyl group. A fungicide for cereals, beet and brassicas used to control a range of diseases including powdery mildew, rusts, bunts and smuts. | triadimenol |
| tricyclazole | A triazolobenzothiazole that is [1,2,4]triazolo[3,4-b][1,3]benzothiazole which is substituted at position 5 by a methyl group. A fungicide used for the control of rice blast, it is not approved for use within the European Union. | tricyclazole |
| tridemorph | A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a tridecyl group. The configuration at positions 2 and 6 is unknown or unspecified. | 2,6-dimethyl-4-tridecylmorpholine |
| trifloxystrobin | The methyl ester of (2E)-(methoxyimino)[2-({[(E)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetic acid. A foliar applied fungicide for cereals which is particularly active against Ascomycetes, Deuteromycetes and Oomycetes | trifloxystrobin |
| triforine | A member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust. | triforine |
| triphenyltin chloride | An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a chloro group. A fungicide used to control blights on potatoes, leaf spot diseases on sugar beet and anthracnose on beans. | fentin chloride |
| uniconazole-p | A (1E)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol that has S configuration at the chiral centre. It is the enantiomer of (R)-uniconazole; the fungicide and plant growth retardant uniconazole is the racemic mixture comprising (R)-uniconazole and uniconazole-P. | uniconazole P |
| validamycin a | A member of the class of validamycins that is (1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol in which the hydroxy group at position 1 has been converted to its beta-D-glucoside and in which one of the hydrogens attached to the nitrogen is replaced by a (1R,4R,5R,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl group. It is the major validamycin produced by Streptomyces hygroscopicus. | validamycin A |
| zinc dibutyldithiocarbamate | A dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid. | zinc dibutyldithiocarbamate |
| zineb | A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU. | zineb |
| ziram | A dithiocarbamate salt that is the zinc salt of dimethyldithiocarbamic acid. It is a broad-spectrum fungicide and bird and animal repellent that is also used to accelerate the vulcanisation of rubber. | ziram |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 13.4413 | 1 | 14 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 9.2295 | 1 | 10 |
| 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase | Arabidopsis thaliana (thale cress) | Potency | 84.0575 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 10.2430 | 2 | 9 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 51.0389 | 4 | 64 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 34.8632 | 2 | 55 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Potency | 39.8107 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 22.0258 | 1 | 20 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 5.5030 | 1 | 8 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 15.4700 | 1 | 5 |
| AR protein | Homo sapiens (human) | Potency | 25.8805 | 11 | 542 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 27.3953 | 3 | 91 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 13.7838 | 11 | 18 |
| Ataxin-2 | Homo sapiens (human) | Potency | 30.3075 | 1 | 37 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 22.6888 | 2 | 4 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 29.2223 | 2 | 53 |
| beta-2 adrenergic receptor | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 34.7393 | 1 | 4 |
| BRCA1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 58.2469 | 1 | 6 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 19.0148 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 18.6952 | 1 | 21 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 22.0244 | 1 | 13 |
| caspase-3 | Homo sapiens (human) | Potency | 18.6952 | 1 | 21 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 22.0244 | 1 | 13 |
| Caspase-7 | Homo sapiens (human) | Potency | 31.6228 | 1 | 2 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 33.0205 | 3 | 138 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 20.8611 | 2 | 9 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 27.4077 | 1 | 7 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 35.0554 | 1 | 4 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 35.6892 | 2 | 6 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 29.1522 | 2 | 10 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 30.1056 | 1 | 5 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 17.1982 | 2 | 23 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 54.3208 | 1 | 4 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 136.6077 | 1 | 6 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 19.7710 | 3 | 8 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 33.2289 | 1 | 6 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 17.1982 | 2 | 23 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 92.1395 | 1 | 4 |
| ClpP | Bacillus subtilis | Potency | 31.6228 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 3.9967 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 1.9953 | 1 | 1 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 8.5449 | 1 | 7 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 29.3070 | 1 | 10 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 6.2560 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 15.9985 | 2 | 20 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 14.8085 | 2 | 13 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 20.8600 | 1 | 77 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 1.7586 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 2.6875 | 1 | 3 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 16.9041 | 1 | 3 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 41.8450 | 1 | 7 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 25.2105 | 1 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 31.6228 | 1 | 1 |
| enteropeptidase precursor | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 30.1788 | 12 | 582 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 28.7467 | 3 | 92 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 25.0015 | 10 | 466 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 22.8761 | 1 | 13 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 21.3349 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 37.8641 | 5 | 125 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 45.8577 | 1 | 2 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 63.0957 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 16.2135 | 1 | 4 |
| G | Vesicular stomatitis virus | Potency | 8.5449 | 1 | 7 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| galactokinase | Homo sapiens (human) | Potency | 30.4625 | 2 | 2 |
| GALC protein | Homo sapiens (human) | Potency | 1.4219 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 15.9985 | 1 | 10 |
| geminin | Homo sapiens (human) | Potency | 12.9568 | 2 | 24 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 16.6929 | 3 | 155 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 21.3300 | 2 | 6 |
| GLS protein | Homo sapiens (human) | Potency | 26.6449 | 1 | 5 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 34.2741 | 5 | 154 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 24.8655 | 1 | 67 |
| glyceraldehyde-3-phosphate dehydrogenase isoform 1 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 13.6996 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 29.0717 | 2 | 3 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 15.1039 | 1 | 4 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 26.7377 | 2 | 76 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 12.2475 | 2 | 19 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 23.0865 | 1 | 10 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 18.8728 | 2 | 34 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 34.5753 | 2 | 52 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 8.5449 | 1 | 7 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 10.1205 | 1 | 6 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 20.6958 | 1 | 5 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 21.1916 | 2 | 69 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 22.5792 | 3 | 12 |
| IDH1 | Homo sapiens (human) | Potency | 10.1233 | 1 | 5 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 8.5449 | 1 | 14 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 21.4509 | 1 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 6.9906 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 6.9906 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 12.5877 | 2 | 9 |
| interleukin 8 | Homo sapiens (human) | Potency | 67.1531 | 1 | 11 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 7.0578 | 2 | 9 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 9.7659 | 1 | 9 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 39.6848 | 3 | 55 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 14.4753 | 2 | 10 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 15.5142 | 3 | 9 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 0.1084 | 3 | 3 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 14.1087 | 1 | 8 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 3.3552 | 1 | 2 |
| Nrf2 | Homo sapiens (human) | Potency | 24.0682 | 1 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 33.3182 | 4 | 218 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 19.2764 | 1 | 4 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 51.8781 | 1 | 13 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 28.5802 | 2 | 48 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 13.2728 | 1 | 14 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 7.9114 | 2 | 44 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 13.8914 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 22.3899 | 3 | 228 |
| P53 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 59.9973 | 1 | 3 |
| Parkin | Homo sapiens (human) | Potency | 2.6651 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 14.7138 | 2 | 8 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 30.6419 | 5 | 167 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 81.1111 | 1 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 30.6399 | 5 | 164 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 39.8107 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 19.0000 | 3 | 9 |
| PINK1 | Homo sapiens (human) | Potency | 2.6651 | 1 | 2 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 8.7983 | 1 | 5 |
| polyprotein | Zika virus | Potency | 16.2135 | 1 | 4 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 15.2887 | 1 | 7 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 14.1698 | 1 | 8 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 33.7273 | 1 | 11 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 38.8178 | 3 | 129 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 36.2313 | 1 | 47 |
| progesterone receptor | Homo sapiens (human) | Potency | 28.6728 | 2 | 86 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 31.6228 | 2 | 3 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 14.1254 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 56.5018 | 2 | 4 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 14.0479 | 2 | 140 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 23.9459 | 3 | 192 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 28.3682 | 4 | 183 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 14.8289 | 1 | 5 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 31.1423 | 3 | 56 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 31.1423 | 3 | 56 |
| Smad3 | Homo sapiens (human) | Potency | 6.5157 | 1 | 8 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 14.0567 | 2 | 7 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 17.1736 | 1 | 11 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 10.5374 | 1 | 6 |
| TDP1 protein | Homo sapiens (human) | Potency | 15.6971 | 2 | 57 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 89.1251 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 32.7279 | 2 | 6 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 21.4757 | 3 | 174 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 42.5040 | 4 | 51 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 32.1665 | 7 | 139 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 21.5892 | 2 | 29 |
| TSHR protein | Homo sapiens (human) | Potency | 2.1331 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 74.9780 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 10.2538 | 3 | 3 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 8.7983 | 1 | 5 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 8.7983 | 1 | 5 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 41.1036 | 2 | 9 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 26.2014 | 2 | 69 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 29.4200 | 5 | 132 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 30.9711 | 1 | 14 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 24.8655 | 1 | 67 |
| Vpr | Human immunodeficiency virus 1 | Potency | 20.0636 | 1 | 3 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 5.8500 | 2 | 4 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.0500 | 1 | 2 |
| 26S proteasome non-ATPase regulatory subunit 14 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 5.5150 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 3.1520 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | IC50 | 5.5150 | 1 | 1 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 3.1520 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 6.2418 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 3.9720 | 1 | 2 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | IC50 | 6.6921 | 1 | 2 |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | Ki | 3.5054 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | IC50 | 6.6921 | 1 | 2 |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | Ki | 3.5054 | 1 | 2 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 201.5000 | 1 | 2 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 5.8500 | 2 | 4 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 2.0500 | 1 | 2 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 130.0000 | 1 | 1 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 1.5574 | 2 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 1.3904 | 1 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 0.7805 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | IC50 | 0.7340 | 1 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 0.4146 | 1 | 2 |
| Aldehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 0.3200 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 1.2350 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | Ki | 1.2250 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.7340 | 1 | 2 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.4146 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 0.7340 | 1 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.4146 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | IC50 | 4.6602 | 1 | 2 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 1.7476 | 1 | 2 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | IC50 | 1.2260 | 1 | 1 |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | Ki | 0.5600 | 1 | 1 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | IC50 | 5.6837 | 1 | 2 |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | Ki | 0.8258 | 1 | 2 |
| Androgen receptor | Rattus norvegicus (Norway rat) | IC50 | 4.9753 | 1 | 1 |
| Androgen receptor | Rattus norvegicus (Norway rat) | Ki | 3.3169 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 207.0000 | 1 | 1 |
| bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase | Mycobacterium tuberculosis H37Rv | IC50 | 89.3200 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 738.6000 | 4 | 5 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Botulinum neurotoxin type A | Clostridium botulinum | IC50 | 16.9500 | 2 | 2 |
| BZLF2 | Human herpesvirus 4 type 2 (Epstein-Barr virus type 2) | IC50 | 5.9700 | 1 | 1 |
| calpain II, partial | Sus scrofa (pig) | IC50 | 4.2424 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Catechol O-methyltransferase | Homo sapiens (human) | IC50 | 2.3736 | 2 | 2 |
| Catechol O-methyltransferase | Rattus norvegicus (Norway rat) | IC50 | 21.3796 | 1 | 1 |
| Chain A, Bacterial leucyl aminopeptidase | Vibrio proteolyticus | Ki | 0.5800 | 1 | 1 |
| Chain A, Methionine aminopeptidase | Escherichia coli | Ki | 0.4000 | 1 | 1 |
| Chain C, Cytochrome b | Bos taurus (cattle) | IC50 | 0.0112 | 1 | 2 |
| Cholinesterase | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Cycloeucalenol cycloisomerase | Zea mays | IC50 | 0.4000 | 1 | 1 |
| Cytochrome b | Sus scrofa (pig) | Ki | 0.1535 | 1 | 3 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 54.0378 | 2 | 3 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 1.2265 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 5.4433 | 2 | 3 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 245.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 2.3500 | 3 | 4 |
| D(3) dopamine receptor | Homo sapiens (human) | IC50 | 4.2180 | 1 | 1 |
| D(3) dopamine receptor | Homo sapiens (human) | Ki | 1.4330 | 1 | 1 |
| Delta | Zea mays | IC50 | 25.0000 | 1 | 1 |
| Deoxyhypusine synthase | Rattus norvegicus (Norway rat) | IC50 | 3.5000 | 1 | 1 |
| Endoplasmic reticulum chaperone BiP | Homo sapiens (human) | IC50 | 9.1000 | 3 | 3 |
| envelope glycoprotein | Human immunodeficiency virus 1 | IC50 | 5.1400 | 3 | 4 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 0.6813 | 1 | 2 |
| Estrogen receptor 1 | Homo sapiens (human) | IC50 | 3.0512 | 1 | 2 |
| estrogen receptor beta isoform 1 | Homo sapiens (human) | IC50 | 39.1488 | 2 | 3 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 17.9374 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 17.9374 | 1 | 1 |
| exodeoxyribonuclease V subunit RecB | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| exodeoxyribonuclease V subunit RecC | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| exodeoxyribonuclease V subunit RecD | Escherichia coli str. K-12 substr. MG1655 | IC50 | 53.3440 | 1 | 1 |
| fatty acid synthase | Homo sapiens (human) | IC50 | 6.7350 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 44.6684 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 6.8240 | 1 | 3 |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | IC50 | 2.2900 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 23.5400 | 5 | 5 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 59.3000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 38.7167 | 3 | 3 |
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | IC50 | 208.0000 | 1 | 1 |
| heat shock 70kDa protein 1A | Homo sapiens (human) | IC50 | 19.3500 | 2 | 2 |
| heat shock cognate 71 kDa protein isoform 1 | Homo sapiens (human) | IC50 | 27.4000 | 1 | 1 |
| heat shock cognate 71 kDa protein isoform 2 | Homo sapiens (human) | IC50 | 27.4000 | 1 | 1 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 0.5500 | 1 | 1 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | IC50 | 750.0000 | 1 | 1 |
| Janus kinase 2 (a protein tyrosine kinase) | Homo sapiens (human) | IC50 | 0.2230 | 1 | 1 |
| Lanosterol 14-alpha demethylase | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 35.1000 | 1 | 2 |
| Lysyl oxidase homolog 2 | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Lysyl oxidase homolog 3 | Homo sapiens (human) | IC50 | 0.1100 | 1 | 1 |
| Lysyl oxidase homolog 4 | Homo sapiens (human) | IC50 | 0.1800 | 1 | 1 |
| M1-family alanyl aminopeptidase | Plasmodium falciparum 3D7 | IC50 | 50.4350 | 1 | 2 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 6.0000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 5.5500 | 2 | 2 |
| Mcl-1 | Homo sapiens (human) | IC50 | 14.6524 | 2 | 5 |
| Methionine aminopeptidase | Escherichia coli K-12 | IC50 | 6.8240 | 1 | 3 |
| Methionine aminopeptidase 1 | Homo sapiens (human) | IC50 | 24.3000 | 3 | 4 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 13.4000 | 3 | 4 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 0.2905 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 0.2028 | 1 | 2 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | IC50 | 2.4844 | 1 | 1 |
| Monoglyceride lipase | Homo sapiens (human) | IC50 | 0.9772 | 1 | 1 |
| Monoglyceride lipase | Rattus norvegicus (Norway rat) | IC50 | 0.0880 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | IC50 | 5.5070 | 1 | 1 |
| Mu-type opioid receptor | Homo sapiens (human) | Ki | 2.2360 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 252.6000 | 1 | 2 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 6.6000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 18.8433 | 1 | 12 |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | IC50 | 18.8433 | 1 | 9 |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | IC50 | 18.8433 | 1 | 9 |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | IC50 | 18.8433 | 1 | 9 |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | IC50 | 18.8433 | 1 | 9 |
| N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | Homo sapiens (human) | IC50 | 1.6000 | 1 | 1 |
| N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | Mus musculus (house mouse) | IC50 | 11.0000 | 1 | 1 |
| Plasminogen activator inhibitor 1 | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Polyamine oxidase 1 | Zea mays | Ki | 0.0075 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 50.1187 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 0.6443 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 | 1,800.0000 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | Ki | 560.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 1.0400 | 1 | 1 |
| Pup--protein ligase | Mycobacterium tuberculosis H37Rv | IC50 | 15.9000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 2.7329 | 1 | 2 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 46.0000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | Ki | 4.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 10.0000 | 1 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 9.7267 | 4 | 6 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 17.6100 | 1 | 2 |
| Retinal dehydrogenase 1 | Homo sapiens (human) | IC50 | 0.0200 | 1 | 1 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 14.6000 | 1 | 1 |
| small ubiquitin-related modifier 2 isoform b precursor | Homo sapiens (human) | IC50 | 12.1450 | 2 | 2 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 2.1810 | 1 | 1 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 1.7330 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 1.2350 | 1 | 1 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 1.2250 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 4.3494 | 1 | 1 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 2.3106 | 1 | 1 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 3.0650 | 2 | 2 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 1.9000 | 1 | 1 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | IC50 | 5.5000 | 1 | 1 |
| Sterol-8,7-isomerase | Zea mays | IC50 | 0.4000 | 1 | 1 |
| Substance-K receptor | Homo sapiens (human) | IC50 | 4.3991 | 1 | 2 |
| Substance-K receptor | Homo sapiens (human) | Ki | 1.4663 | 1 | 2 |
| SUMO-1 | Homo sapiens (human) | IC50 | 22.2500 | 2 | 2 |
| Thermolysin | Bacillus thermoproteolyticus | IC50 | 350.0000 | 1 | 2 |
| Thermolysin | Bacillus thermoproteolyticus | Ki | 214.0000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 75.5000 | 1 | 2 |
| Thromboxane-A synthase | Homo sapiens (human) | IC50 | 2.4635 | 1 | 2 |
| Tissue-type plasminogen activator | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | IC50 | 2.7000 | 2 | 2 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 3.4780 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 2.3438 | 1 | 2 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | IC50 | 3.8000 | 1 | 1 |
| Valosin-containing protein | Homo sapiens (human) | IC50 | 27.7440 | 2 | 2 |