Cor Pulmonale

Hypertrophy and dilation of the RIGHT VENTRICLE of the heart that is caused by PULMONARY HYPERTENSION. This condition is often associated with pulmonary parenchymal or vascular diseases, such as CHRONIC OBSTRUCTIVE PULMONARY DISEASE and PULMONARY EMBOLISM.

Synonym
Diseases, Pulmonary Heart
Heart Disease, Pulmonary
Heart Diseases, Pulmonary
Cor Pulmonale
Disease, Pulmonary Heart
Pulmonary Heart Diseases
Pulmonary Heart Disease

Excerpt	Reference
"Chronic cor pulmonale is more prevalent in northern India than in the south."	( Arora, R; Padmavati, S, 1976)
"Cor pulmonale is a maladaptive response to pulmonary hypertension."	( Eden, E; Minkin, R; Shujaat, A, 2007)
"Cor pulmonale (pulmonary heart disease) is a chronic progressive complicated disease for which treatment needs to be sustained all the time, creating a great financial burden on individuals and society."	( Chen, S; Huang, Y; Liu, Y; Qin, X; Qu, J; Zhao, C; Zhu, Q, 2014)
"Cor pulmonale is a clinical syndrome associated with pulmonary hypertension, frequently complicated by congestive heart failure, commonly caused by chronic obstructive pulmonary disease (COPD)."	( Arrotti, S; Boriani, G; Coppi, F; Monopoli, DE; Rossi, R; Sgura, FA; Talarico, M, 2023)

Excerpt	Reference
"Most patients with cor pulmonale have tachycardia."	( Arrotti, S; Boriani, G; Coppi, F; Monopoli, DE; Rossi, R; Sgura, FA; Talarico, M, 2023)

Excerpt	Reference
"Ten patients with cor pulmonale complicating severe chronic bronchitis and emphysema have been treated with 2 litres/min of oxygen for prolonged periods in the day, at home, over 12 to 62 months."	( Clancy, L; Cooke, NJ; Flenley, DC; Kirby, BJ; Leggett, RJ; Leitch, AG, 1976)
"After treatment for cor pulmonale theophylline clearance improved; however, with the subsequent onset of fever and pneumonia the clearance decreased again, illustrating the potential lability of theophylline clearance."	( Matthay, MA; Matthay, RA; Weinberger, MM, 1976)
"Captopril administration in chronic cor pulmonale (CCP) stage I and II produced positive objective and subjective responses evident from a significant improvement of right heart myocardial contractility, external respiration which lower systolic pressure in the artery."	( Dobrotvorskaia, TE; Morozova, VT, 1991)
"A group of 36 patients with cor pulmonale chronicum were treated for 12 months with ibopamine, a dopamine-related drug, orally active, suitable for the long-term therapy of congestive heart failure."	( Bianco, L; Cantoni, V; Cicchetti, V; Ghirardi, P; Marchetti, GV; Sabino, F, 1988)
"The pulmonary hypertension of cor pulmonale can be reversed by sustained correction of hypoxia but continuous oxygen treatment poses problems in clinical practice."	( Campbell, IA; Ebejer, MJ; Henderson, AH; Higgins, DA; Singh, H, 1985)
"We conclude that in patients with pulmonary heart disease, the right ventricular ejection fraction is abnormal and improves with digoxin treatment only when the left ventricular ejection fraction also is initially abnormal."	( Campbell, EJ; Mathur, PN; McEwan, MP; Powles, P; Pugsley, SO, 1981)
"40 Patients with chronic cor pulmonale (CCP) were treated with Feiyaning (FYN), a Yiqi Huoxue compound prescription, and ligustrazine (LT) were reported."	( Liu, SM; Tang, TQ, 1994)
"Thirty caseas of cor pulmonale with heart failure were treated with PGE1 at a dose of 200 micrograms."	( Hu, Z; Wang, W; Zhou, SC, 1997)
"PGE1 is effective in therapy of cor pulmonale with heart failure."	( Hu, Z; Wang, W; Zhou, SC, 1997)
"Forty cases of chronic pulmonary heart disease at the acute stage were treated with PGE1 at the dosage of 100 micrograms."	( Huang, CC; Xu, M, 2001)
"Cor pulmonale (pulmonary heart disease) is a chronic progressive complicated disease for which treatment needs to be sustained all the time, creating a great financial burden on individuals and society."	( Chen, S; Huang, Y; Liu, Y; Qin, X; Qu, J; Zhao, C; Zhu, Q, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	970 (78.54)	23.3326
1990's	147 (11.90)	12.5806
2000's	59 (4.78)	18.1394
2010's	44 (3.56)	28.8240
2020's	15 (1.21)	9.53

Drug	Relationship Strength	Studies	Trials
acetylcarnitine	low	1	0
2,3-diphosphoglycerate	low	1	0
ammonium hydroxide	medium	20	1
bromide	low	1	0
carbon monoxide	low	5	0
chlorine	low	9	0
coumarin	low	1	0
methylmalonic acid	low	1	0
n(g),n(g')-dimethyl-l-arginine	low	1	0
creatine	low	3	0
lactic acid	low	2	0
formaldehyde	low	2	0
hydrogen carbonate	medium	20	1
dalteparin	medium	1	1
histamine	low	5	0
indoleacetic acid	low	2	0
iodine	low	2	0
dihydroxyphenylalanine	low	1	0
thioctic acid	low	1	0
methanol	low	2	0
nickel	low	1	0
niacinamide	low	2	0
niacin	low	12	0
nitrates	low	4	0
nitrous oxide	low	1	0
parathion	low	1	0
pteridines	low	1	0
pyruvic acid	low	1	0
sulfur dioxide	low	3	0
thiamine	low	3	0
uric acid	low	5	0
urea	low	3	0
xanthine	low	1	0
aminopropionitrile	low	1	0
phenytoin	low	2	0
hydroxyindoleacetic acid	low	4	0
acebutolol	low	1	0
acetazolamide	low	18	0
albendazole	low	1	0
albuterol	medium	3	1
theophylline	medium	37	1
amiodarone	low	1	0
amitriptyline	low	1	0
amlodipine	low	1	0
aspirin	low	4	0
azathioprine	low	3	0
bendroflumethiazide	low	1	0
caffeine	low	1	0
verapamil	low	5	0
carvedilol	low	1	0
chlorothiazide	low	10	0
chlorpromazine	low	1	0
chlorthalidone	low	4	0
clofibrate	low	1	0
diazepam	low	2	0
dichlorphenamide	low	3	0
diphenhydramine	low	1	0
dipyridamole	medium	5	1
disopyramide	medium	2	1
racemetirosine	low	1	0
doxapram	low	3	0
dyphylline	medium	1	1
edrophonium	low	1	0
ethacrynic acid	low	13	0
etilefrine	low	1	0
berotek	low	1	0
fleroxacin	medium	1	1
flunitrazepam	low	1	0
fluorouracil	medium	1	1
furosemide	medium	25	2
gentamicin	medium	1	1
guaifenesin	low	7	0
hydralazine	medium	12	2
hydrochlorothiazide	medium	8	2
hydroxyurea	low	1	0
lidocaine	low	4	0
mephentermine	low	1	0
amrinone	low	3	0
indapamide	low	1	0
indomethacin	low	1	0
iomeprol	low	1	0
iothalamic acid	low	1	0
iproniazid	low	1	0
isoniazid	low	4	0
isoproterenol	medium	14	1
khellin	low	2	0
lidoflazine	medium	1	1
losartan	medium	3	1
meperidine	low	3	0
metaproterenol	low	4	0
metformin	low	1	0
methadone	low	2	0
methylphenidate	low	1	0
mexiletine	medium	3	3
milrinone	low	1	0
molsidomine	low	5	0
deoxyepinephrine	low	1	0
apnea	low	8	0
nifedipine	medium	30	4
nitrendipine	medium	2	1
nitroglycerin	medium	17	2
octopamine	low	1	0
papaverine	low	1	0
pentoxifylline	low	2	0
phenindione	low	1	0
phenobarbital	low	3	0
phenylbutazone	low	2	0
pimobendan	medium	1	1
pirbuterol	medium	3	1
potassium chloride	low	3	0
potassium iodide	low	1	0
practolol	low	1	0
praziquantel	low	1	0
prazosin	low	2	0
procaine	low	3	0
promethazine	low	2	0
propranolol	low	4	0
sodium iodide	low	1	0
succinylcholine	low	1	0
sulfanilamide	low	1	0
sulfobromophthalein	low	3	0
terbutaline	low	2	0
krypton	low	3	0
theobromine	low	3	0
thioridazine	low	1	0
nikethamide	low	2	0
tolazamide	low	1	0
tolazoline	low	4	0
triamterene	medium	9	1
trimethoprim	low	1	0
tripelennamine	low	1	0
urapidil	low	1	0
corticosterone	low	1	0
prednisolone	low	8	0
reserpine	low	7	0
cephaloridine	low	1	0
phentolamine	low	6	0
sorbitol	low	2	0
thyroxine	low	3	0
spironolactone	medium	19	1
aldosterone	medium	11	3
penicillamine	low	1	0
prednisone	low	11	0
dehydroepiandrosterone	low	1	0
penicillin g	low	1	0
metaraminol	low	2	0
triiodothyronine	low	2	0
chloramphenicol	low	3	0
aspartic acid	low	3	0
methyltestosterone	low	1	0
galactose	low	3	0
phenylephrine	low	1	0
levodopa	low	1	0
methoxamine	low	1	0
adenosine monophosphate	low	2	0
methylene blue	low	3	0
bretylium tosylate	low	1	0
leucine	low	1	0
methacholine chloride	medium	1	1
methionine	low	1	0
phenylalanine	low	1	0
gallamine triethiodide	low	1	0
strophanthidin	low	1	0
norethynodrel	low	1	0
chlorisondamine	low	3	0
ampicillin	low	3	0
mannitol	low	1	0
arginine	low	2	0
ethane	low	1	0
triamcinolone acetonide	low	1	0
phencyclidine	low	19	0
tromethamine	low	3	0
isoprene	low	1	0
trichloroethylene	low	1	0
dehydrocholic acid	low	1	0
methylprednisolone	low	1	0
syrosingopine	low	1	0
isosorbide dinitrate	medium	10	2
2-methylpentane	low	1	0
pyrroles	low	2	0
heptanol	low	1	0
phenformin	low	1	0
meglumine	low	1	0
diphenhydramine hydrochloride	low	2	0
thiamine pyrophosphate	low	3	0
quinazolines	low	1	0
oxazoles	low	4	0
thiazoles	low	1	0
pyrazines	medium	11	2
ephedrine	low	3	0
monocrotaline	low	20	0
aminophylline	low	33	0
prenylamine	low	1	0
xanthinol niacinate	low	1	0
n-pentyl nitrite	low	1	0
dihydralazine	low	1	0
phenylpropanolamine	low	1	0
medroxyprogesterone	low	1	0
oxophenarsine	low	1	0
malondialdehyde	low	4	0
lucanthone hydrochloride	low	1	0
acetylcysteine	low	1	0
clopamide	medium	6	2
erythromycin	low	1	0
dehydroepiandrosterone sulfate	low	1	0
ethambutol	low	2	0
tetramethylpyrazine	medium	11	2
prothipendyl	low	1	0
d-alpha tocopherol	low	4	0
tocopherols	low	1	0
benperidol	low	1	0
aminorex	low	1	0
streptomycin	low	5	0
carbonates	low	1	0
trimetazidine	low	1	0
mercury	low	1	0
plutonium	low	1	0
tantalum	low	1	0
technetium	low	9	0
cadmium	low	1	0
gold	low	2	0
helium	low	1	0
xenon	low	3	0
ferric chloride	low	1	0
bromine	low	1	0
barium sulfate	low	1	0
calcium phosphate, dibasic, anhydrous	low	1	0
calcium phosphate, monobasic, anhydrous	low	1	0
tricalcium phosphate	low	1	0
chlorine	low	2	0
thallium chloride	low	1	0
ozone	low	1	0
trolamine salicylate	low	3	0
chrysotile	low	1	0
ammonium chloride	low	2	0
urobilinogen	low	1	0
levamisole	low	2	0
cromolyn sodium	low	1	0
deslanoside	low	3	0
paraldehyde	low	1	0
4-methoxyamphetamine	low	4	0
transferrin	low	2	0
cefazolin	medium	1	1
almitrine	medium	6	2
dobutamine	low	3	0
methyldopa	medium	2	1
diltiazem	medium	3	1
nonachlazine	medium	1	1
prenalterol	low	1	0
captopril	medium	10	2
doxofylline	low	1	0
fomesafen	low	2	0
atorvastatin	low	1	0
iopamidol	low	1	0
glucose-1-phosphate	low	1	0
tropodifene	low	1	0
tolafentrine	low	1	0
xenon radioisotopes	low	2	0
1,7-phenanthroline	low	2	0
delphinidin	low	2	0
ibopamine	low	1	0
prethcamide	low	7	0
nicotine	low	1	0
fibrinogen	low	10	0
dextromoramide	low	1	0
monocrotaline pyrrole	low	2	0
imipenem, anhydrous	low	1	0
bosentan anhydrous	low	2	0
dehydroretronecine	low	1	0
perindopril	medium	6	2
1-hexadecyl-2-acetyl-glycero-3-phosphocholine	low	1	0
tadalafil	low	1	0
tanshinone	low	1	0
n,n-dimethylarginine	low	1	0
olmesartan medoxomil	low	1	0
ivabradine	low	1	0
xamoterol	medium	1	1
calcium pyrophosphate	low	1	0
technetium tc 99m pentetate	low	1	0
angiotensin ii	medium	11	1
atropine	low	9	0
cortisone	low	2	0
benzofurans	low	1	0
lanatosides	low	7	0
glycogen	low	1	0
fibrin	low	4	0
elastin	low	2	0
oxytocin	low	1	0
ouabain	low	4	0
inositol 3-phosphate	low	1	0
quinidine	low	5	0
digitoxin	medium	28	2
convallatoxin	medium	4	1
ferulic acid	low	1	0
diethylstilbestrol	low	1	0
cefamandole	low	1	0
riboflavin	low	2	0
glycosides	low	3	0
chalcone	low	1	0
arginine vasopressin	low	1	0
canrenoic acid	medium	1	1
lanatoside c	low	3	0
methimazole	low	1	0
digoxin	medium	58	10
nadp	low	1	0
thiopental	low	2	0
17-ketosteroids	low	5	0
flosequinan	medium	1	1
myelin basic protein	low	1	0
bilirubin	low	6	0
dinoprost	low	1	0
vitamin k semiquinone radical	low	1	0
thromboxane a2	low	3	0
alprostadil	medium	5	1
6-ketoprostaglandin f1 alpha	low	9	0
11-dehydro-thromboxane b2	low	1	0
coenzyme q10	low	1	0
2,3-dinor-6-ketoprostaglandin f1alpha	low	2	0
thromboxane b2	low	9	0
2,3-dinor-thromboxane b2	low	1	0
phenylephrine hydrochloride	low	1	0
acetyldigitoxin	low	1	0
hydromorphone	low	2	0
nalorphine	low	1	0
naloxone	low	1	0
proscillaridin	low	2	0
lobeline	low	1	0
morphine	low	7	0
iloprost	low	2	0
antimony	low	1	0
barium	low	1	0
aluminum	low	1	0
thallium	low	13	0
arsenic	low	1	0
lisinopril	medium	1	1
ramipril	medium	4	1
puerarin	low	1	0
enalapril	medium	7	3
fumarates	low	3	0
beryllium	low	2	0
cysteine	low	1	0
silicon	low	2	0
phosphorus	low	2	0
heroin	low	3	0
oxyfedrine	medium	1	1
triolein	low	1	0
cefotaxime	low	1	0
saralasin	low	1	0
selenium	low	1	0
pregnanediol	low	2	0
limaprost	low	1	0
technetium tc 99m pyrophosphate	low	2	0
beta-escin	medium	3	1
butylscopolammonium bromide	low	1	0
ergoline	low	1	0
losartan potassium	low	3	0
indocyanine green	low	3	0
pituitrin	low	3	0
acid phosphatase	low	2	0
atrial natriuretic factor	medium	9	1
gastrins	low	1	0
glucagon	low	6	0
beta-endorphin	low	1	0
natriuretic peptide, c-type	low	1	0
endothelin-1	medium	10	1
ubiquinone	low	1	0
k-strophanthin-beta	low	1	0
tanshinone ii a sodium sulfonate	low	1	0
sodium pertechnetate tc 99m	low	2	0
sodium ethylxanthate	low	3	0
meglumine cyclic adenylate	low	1	0
cardiovascular agents	low	6	0
piperidines	medium	7	2
interleukin-8	low	1	0
methylcellulose	low	3	0
natriuretic peptide, brain	medium	20	2
heme	low	1	0
ascorbic acid	low	1	0
tetracycline	low	5	0
methacycline	low	1	0
salicylates	low	1	0
warfarin	low	7	0
teriflunomide	low	1	0
mebolazine	low	1	0
transforming growth factor beta	low	2	0
antimony potassium tartrate	low	1	0
hirudin	low	1	0
adrenomedullin	low	2	0
epoetin alfa	low	1	0
vitamin b 12	low	3	0
thromboplastin	low	2	0
cyclic gmp	low	2	0
hypoxanthine	low	1	0
inosine	low	1	0
sapropterin	low	1	0
rifampin	low	5	0
allopurinol	low	1	0
sildenafil citrate	low	3	0
eye	low	1	0
phosphorus radioisotopes	low	1	0

Protein Targets (1,763)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	47	0	0	47
Chain A, Cruzipain	13	0	0	13
regulator of G-protein signaling 4	38	0	0	38
Platelet-activating factor receptor	0	2	0	3
Inositol monophosphatase 1	20	0	0	20
geminin	90	0	0	90
lamin isoform A-delta10	83	0	0	83
Guanine nucleotide-binding protein G	12	0	0	12
aldehyde dehydrogenase 1 family, member A1	52	0	0	52
retinoic acid nuclear receptor alpha variant 1	68	0	0	68
retinoid X nuclear receptor alpha	62	0	0	62
estrogen-related nuclear receptor alpha	88	0	0	88
pregnane X nuclear receptor	76	0	0	76
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	30	0	0	30
Luciferase	30	0	0	30
thioredoxin reductase	69	0	0	69
SMAD family member 2	28	0	0	28
SMAD family member 3	28	0	0	28
AR protein	100	0	0	100
progesterone receptor	50	0	0	50
estrogen nuclear receptor alpha	123	0	0	123
peroxisome proliferator-activated receptor delta	40	0	0	40
vitamin D (1,25- dihydroxyvitamin D3) receptor	53	0	0	53
thyroid hormone receptor beta isoform 2	61	0	0	61
serine/threonine-protein kinase PLK1	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 1	73	0	0	73
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial	0	1	0	1
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	0	1	0	1
Gamma-butyrobetaine dioxygenase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	9	1	10
5-hydroxytryptamine receptor 2A	0	12	1	13
5-hydroxytryptamine receptor 1A	0	21	4	26
5-hydroxytryptamine receptor 1B	0	16	1	17
5-hydroxytryptamine receptor 1D	0	3	1	4
5-hydroxytryptamine receptor 1F	0	3	1	4
5-hydroxytryptamine receptor 2B	0	9	1	10
5-hydroxytryptamine receptor 6	0	1	1	2
Sodium-dependent serotonin transporter	0	22	1	23
Sodium-dependent serotonin transporter	0	6	0	6
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 5A	0	1	1	2
5-hydroxytryptamine receptor 5B	0	1	1	2
5-hydroxytryptamine receptor 3A	0	1	1	2
5-hydroxytryptamine receptor 4	0	1	1	2
5-hydroxytryptamine receptor 3B	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	2	0	7
Solute carrier family 22 member 1	0	25	0	31
Beta-2 adrenergic receptor	0	11	15	27
Beta-1 adrenergic receptor	0	14	11	25
Beta-3 adrenergic receptor	0	7	10	17
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	35	0	0	35
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	5	0	5
GALC protein	12	0	0	12
GLI family zinc finger 3	79	0	0	79
nuclear receptor subfamily 1, group I, member 3	57	0	0	57
cytochrome P450 family 3 subfamily A polypeptide 4	57	0	0	57
glucocorticoid receptor [Homo sapiens]	88	0	0	88
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	3	0	3
arylsulfatase A	38	0	0	38
Carbonic anhydrase	0	3	0	3
euchromatic histone-lysine N-methyltransferase 2	96	0	0	96
Bloom syndrome protein isoform 1	31	0	0	31
thyroid hormone receptor beta isoform a	35	0	0	35
peripheral myelin protein 22	40	0	0	40
survival motor neuron protein isoform d	32	0	0	32
muscleblind-like protein 1 isoform 1	20	0	0	20
Gamma-aminobutyric acid receptor subunit pi	39	8	4	51
ATP-binding cassette sub-family C member 3	0	76	0	76
Multidrug resistance-associated protein 4	0	77	0	81
Carbonic anhydrase	0	3	0	3
Solute carrier family 22 member 6	0	11	0	11
Carbonic anhydrase 12	0	14	2	28
Prolyl endopeptidase	0	2	0	2
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	114	0	114
Glycogen phosphorylase, muscle form	0	3	0	3
Renin	0	5	0	5
Carbonic anhydrase 1	0	30	2	48
Carbonic anhydrase 2	0	34	3	54
Carbonic anhydrase 2	0	3	1	4
Cytochrome P450 1A2	0	8	1	9
Carbonic anhydrase 3	0	13	2	22
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	17	1	20
Steryl-sulfatase	0	1	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	5	0	5
Cytochrome P450 2D6	0	13	1	14
Cytochrome P450 2A6	0	4	1	6
Cytochrome P450 2C9	0	25	1	26
Androgen receptor	0	17	0	18
Gamma-aminobutyric acid receptor subunit beta-1	39	8	4	51
Translocator protein	0	3	3	7
Gamma-aminobutyric acid receptor subunit delta	39	8	4	51
Gamma-aminobutyric acid receptor subunit gamma-2	39	8	4	51
Gamma-aminobutyric acid receptor subunit alpha-5	39	8	4	51
Gamma-aminobutyric acid receptor subunit alpha-3	39	8	4	51
Cannabinoid receptor 1	0	2	0	2
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	3	1	4
Carbonic anhydrase 4	0	21	2	33
Carbonic anhydrase 6	0	15	2	27
Gamma-aminobutyric acid receptor subunit gamma-1	39	8	4	51
Gamma-aminobutyric acid receptor subunit alpha-2	39	8	4	51
Carbonic anhydrase 5A, mitochondrial	0	3	0	3
Adenosine receptor A1	0	9	0	14
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	39	8	4	51
Gamma-aminobutyric acid receptor subunit gamma-3	39	8	4	51
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	39	8	4	51
Adenosine receptor A2a	0	12	1	20
Delta-type opioid receptor	0	11	1	15
Cytochrome P450 2C19	0	10	0	10
Delta-type opioid receptor	0	11	5	17
Mu-type opioid receptor	0	12	4	19
Carbonic anhydrase 5A, mitochondrial	0	18	2	32
Carbonic anhydrase	0	9	0	12
Kappa-type opioid receptor	0	7	1	11
Carbonic anhydrase 7	0	13	2	25
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	9	1	0	10
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	2	0	2
Carbonic anhydrase	0	3	0	7
D(2) dopamine receptor	0	8	0	9
Gamma-aminobutyric acid receptor subunit alpha-1	39	9	4	52
Gamma-aminobutyric acid receptor subunit beta-3	39	8	4	51
Gamma-aminobutyric acid receptor subunit beta-2	39	8	4	51
Cholinesterase	0	3	0	3
Carbonic anhydrase	0	2	0	2
Mu-type opioid receptor	0	11	2	13
Fatty-acid amide hydrolase 1	0	4	0	4
Beta-carbonic anhydrase 1	0	4	0	4
Carbonic anhydrase 2	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	5	1	9
Squalene synthase	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	4	2	7
Carbonic anhydrase 9	0	20	2	35
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	4	0	4
Carbonic anhydrase	0	3	0	7
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	3	0	8
Carbonic anhydrase	0	3	0	8
Carbonic anhydrase	0	4	0	4
Sigma intracellular receptor 2	0	3	0	3
Delta carbonic anhydrase	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	3	2	5
Renin	0	1	0	1
Carbonic anhydrase	0	3	0	7
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	6	2	11
GABA theta subunit	39	8	4	51
Canalicular multispecific organic anion transporter 1	0	70	0	70
Carbonic anhydrase 4	0	5	0	7
Carbonic anhydrase 15	0	10	0	14
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	12	0	22
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	39	8	4	51
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 14	0	13	2	26
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	13	2	27
Chain A, JmjC domain-containing histone demethylation protein 3A	18	0	0	18
Chain A, 2-oxoglutarate Oxygenase	30	0	0	30
Chain A, ATP-DEPENDENT DNA HELICASE Q1	13	0	0	13
acetylcholinesterase	30	0	0	30
dopamine D1 receptor	14	0	0	14
15-lipoxygenase, partial	14	0	0	14
pregnane X receptor	11	0	0	11
phosphopantetheinyl transferase	39	0	0	39
RAR-related orphan receptor gamma	72	0	0	72
USP1 protein, partial	42	0	0	42
NFKB1 protein, partial	20	0	0	20
Microtubule-associated protein tau	42	0	0	42
Thrombopoietin	14	0	0	14
farnesoid X nuclear receptor	44	0	0	44
D(1A) dopamine receptor	21	0	0	21
heat shock protein beta-1	26	0	0	26
flap endonuclease 1	19	0	0	19
muscarinic acetylcholine receptor M1	31	0	0	31
Histone deacetylase 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase 1	0	2	0	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	2	0	2
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Ataxin-2	40	0	0	40
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
ATP-dependent phosphofructokinase	45	0	0	45
Chain A, Glycogen Phosphorylase B	0	0	1	1
Chain B, Glycogen Phosphorylase B	0	0	1	1
Chain A, ADP-dependent glucokinase	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, phosphodiesterase-nucleotide pyrophosphatase	0	1	0	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain B, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
Chain A, GLYCOGEN PHOSPHORYLASE B	0	0	1	1
v-jun sarcoma virus 17 oncogene homolog (avian)	39	0	0	39
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	1	1
Transient receptor potential cation channel subfamily M member 2	0	1	0	1
Alcohol dehydrogenase E chain	0	2	0	2
Alcohol dehydrogenase S chain	0	2	0	2
L-lactate dehydrogenase A chain	0	1	1	2
Adenylate kinase isoenzyme 1	0	0	0	1
Fructose-1,6-bisphosphatase 1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	6	0	7
Fructose-1,6-bisphosphatase 1	0	1	0	1
2-dehydropantoate 2-reductase	0	1	1	2
Inosine-5'-monophosphate dehydrogenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Amine oxidase [flavin-containing] B	0	3	0	3
5'-nucleotidase	0	0	0	1
Choline O-acetyltransferase	0	1	0	1
Adenylate kinase 2, mitochondrial	0	1	0	2
GTP:AMP phosphotransferase AK3, mitochondrial	0	0	0	1
Adenosine receptor A1	0	10	3	17
Adenylate kinase isoenzyme 1	0	1	0	2
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	0	1
Glycine--tRNA ligase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Adenosine deaminase-like protein	0	0	0	1
Protease	0	2	1	3
P2Y purinoceptor 11	0	0	1	1
Histamine H3 receptor	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
5'-AMP-activated protein kinase subunit beta-1	0	0	2	2
glp-1 receptor, partial	30	0	0	30
hypoxia-inducible factor 1 alpha subunit	22	0	0	22
ATAD5 protein, partial	35	0	0	35
Fumarate hydratase	17	0	0	17
TDP1 protein	81	0	0	81
caspase 7, apoptosis-related cysteine protease	11	0	0	11
polyprotein	17	0	0	17
67.9K protein	25	0	0	25
peroxisome proliferator activated receptor gamma	53	0	0	53
caspase-3	11	0	0	11
IDH1	36	0	0	36
aryl hydrocarbon receptor	38	0	0	38
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	37	0	0	37
nuclear receptor subfamily 1, group I, member 2	10	0	0	10
Histone H2A.x	27	0	0	27
cellular tumor antigen p53 isoform a	17	0	0	17
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	17	0	0	17
chromobox protein homolog 1	59	0	0	59
nuclear factor erythroid 2-related factor 2 isoform 2	22	0	0	23
transcriptional regulator ERG isoform 3	7	0	0	7
histone deacetylase 9 isoform 3	7	0	0	7
mitogen-activated protein kinase 1	27	0	0	27
urokinase-type plasminogen activator precursor	15	0	0	15
plasminogen precursor	15	0	0	15
urokinase plasminogen activator surface receptor precursor	15	0	0	15
Vif	0	1	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	1	0	5
neuropeptide S receptor isoform A	14	0	0	14
Voltage-dependent calcium channel gamma-2 subunit	28	0	0	28
Interferon beta	50	0	0	50
Cellular tumor antigen p53	63	0	0	63
Integrin beta-3	13	1	0	14
Integrin alpha-IIb	13	1	0	14
Methionine aminopeptidase	0	1	0	1
Glutamate receptor 2	30	0	0	30
ATPase family AAA domain-containing protein 5	26	0	0	26
GLS protein	46	0	0	46
NPYLR7B	0	0	4	4
thyroid stimulating hormone receptor	29	0	0	29
60 kDa chaperonin	0	4	0	4
60 kDa heat shock protein, mitochondrial	0	6	0	6
10 kDa heat shock protein, mitochondrial	0	6	0	6
Thiosulfate sulfurtransferase	0	6	0	6
Beta-2 adrenergic receptor	0	1	6	11
60 kDa chaperonin	0	6	0	6
10 kDa chaperonin	0	6	0	6
Beta-2 adrenergic receptor	0	6	7	15
Sex hormone-binding globulin	0	0	5	5
Corticosteroid-binding globulin	0	5	0	5
Mineralocorticoid receptor	0	5	4	10
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	7
interleukin 8	16	0	0	16
thyroid stimulating hormone receptor	38	0	0	38
estrogen receptor 2 (ER beta)	39	0	0	39
ras-related protein Rab-9A	12	0	0	12
Polyphenol oxidase 2	0	7	0	9
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	8	6	16
Xanthine dehydrogenase/oxidase	0	3	0	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	6
Purine nucleoside phosphorylase	0	0	1	1
TAR DNA-binding protein 43	21	0	0	21
Shiga toxin subunit A	0	1	0	1
Histamine H3 receptor	0	2	0	6
Thromboxane-A synthase	0	5	0	5
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostacyclin receptor	0	4	3	7
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	2	0	5
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Lysyl oxidase homolog 2	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
PPM1D protein	10	0	0	10
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	24	0	0	24
EWS/FLI fusion protein	38	0	0	38
G	37	0	0	37
cytochrome P450 2D6	44	0	0	44
cytochrome P450 2D6 isoform 1	21	0	0	21
cytochrome P450 2C9 precursor	17	0	0	17
potassium voltage-gated channel subfamily H member 2 isoform d	30	0	0	30
huntingtin isoform 2	11	0	0	11
serine/threonine-protein kinase mTOR isoform 1	15	0	0	15
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	21	0	0	21
nuclear receptor ROR-gamma isoform 1	26	0	0	26
cytochrome P450 3A4 isoform 1	39	0	0	39
lethal factor (plasmid)	20	0	0	20
Polyunsaturated fatty acid lipoxygenase ALOX15B	13	0	0	13
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	10
Solute carrier organic anion transporter family member 1A4	0	5	0	10
Voltage-dependent L-type calcium channel subunit alpha-1F	0	15	0	15
5-hydroxytryptamine receptor 4	0	26	1	27
Lysine-specific demethylase PHF2	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	37	0	0	37
Thyroid hormone receptor alpha	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	2	0	2
Tyrosine-protein kinase Fyn	0	7	0	7
ATP-dependent translocase ABCB1	0	8	0	8
Aldo-keto reductase family 1 member B1	0	18	0	18
Muscarinic acetylcholine receptor M2	0	18	2	24
Muscarinic acetylcholine receptor M4	0	14	1	18
ATP-dependent translocase ABCB1	0	25	2	40
Muscarinic acetylcholine receptor M5	0	14	1	18
Alpha-2A adrenergic receptor	0	24	5	33
Adenosine receptor A3	0	10	1	11
Thyroid hormone receptor alpha	0	3	3	6
Thyroid hormone receptor beta	0	3	3	6
Muscarinic acetylcholine receptor M1	0	17	2	23
D(2) dopamine receptor	0	18	1	20
Alpha-1B adrenergic receptor	0	21	5	26
Lethal factor	0	1	0	1
Alpha-2B adrenergic receptor	0	21	3	28
Thyroid hormone receptor beta	0	3	0	3
Muscarinic acetylcholine receptor M3	0	17	2	22
ATP-dependent translocase ABCB1	0	8	0	9
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	16	1	18
D(4) dopamine receptor	0	10	0	11
Carnitine O-palmitoyltransferase 2, mitochondrial	0	2	0	2
Sodium-dependent noradrenaline transporter	0	20	1	21
Histamine H2 receptor	0	13	2	15
Endothelin-1 receptor	0	6	1	7
5-hydroxytryptamine receptor 2A	0	24	1	25
5-hydroxytryptamine receptor 2C	0	26	1	27
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	4	1	7
Melanocortin receptor 4	0	4	0	4
C-8 sterol isomerase	0	2	0	2
Melanocortin receptor 5	0	4	0	4
Mu-type opioid receptor	0	18	5	25
D(3) dopamine receptor	0	22	0	23
Sodium channel protein type 1 subunit alpha	0	9	0	9
Sodium channel protein type 4 subunit alpha	0	9	0	10
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	15	3	20
Kappa-type opioid receptor	0	17	5	24
5-hydroxytryptamine receptor 2B	0	26	1	27
C-C chemokine receptor type 2	0	4	0	4
Melanocortin receptor 3	0	4	0	4
Alpha-1A adrenergic receptor	0	23	5	28
Histamine H2 receptor	24	1	2	30
5-hydroxytryptamine receptor 6	0	18	1	19
Carnitine O-palmitoyltransferase 1, liver isoform	0	2	0	2
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	41	2	2	45
Sodium channel protein type 7 subunit alpha	0	7	0	7
Voltage-dependent L-type calcium channel subunit alpha-1D	0	15	0	15
Sodium-dependent dopamine transporter	0	18	0	18
Potassium voltage-gated channel subfamily H member 2	0	39	0	39
Voltage-dependent L-type calcium channel subunit alpha-1S	0	15	0	15
Voltage-dependent L-type calcium channel subunit alpha-1C	0	20	0	21
Sodium channel protein type 5 subunit alpha	0	16	0	16
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	10	0	10
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	2	0	2
Inositol hexakisphosphate kinase 1	37	0	0	37
Sodium channel protein type 2 subunit alpha	0	9	0	9
Sigma non-opioid intracellular receptor 1	0	19	1	20
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	1	2
Sodium channel protein type 3 subunit alpha	0	10	0	10
Sodium channel protein type 11 subunit alpha	0	7	0	7
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	7	0	7
Sodium channel protein type 10 subunit alpha	0	7	0	7
cytochrome P450 2C9, partial	37	0	0	37
Chain A, HADH2 protein	28	0	0	28
Chain B, HADH2 protein	28	0	0	28
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
Albumin	0	0	5	5
High affinity nerve growth factor receptor	0	1	2	3
Muscarinic acetylcholine receptor M1	0	9	3	14
Muscarinic acetylcholine receptor M3	0	8	3	13
Muscarinic acetylcholine receptor M4	0	9	3	14
Muscarinic acetylcholine receptor M5	0	8	3	13
Muscarinic acetylcholine receptor M2	0	8	3	14
Angiotensin-converting enzyme	0	20	0	21
Alpha-2C adrenergic receptor	0	20	4	28
D(1B) dopamine receptor	0	2	0	3
UDP-glucuronosyltransferase 1A4	0	2	0	4
Alpha-1D adrenergic receptor	0	21	4	30
Histamine H1 receptor	0	6	1	7
Histamine H1 receptor	0	15	2	17
UDP-glucuronosyltransferase 1A3	0	0	0	2
5-hydroxytryptamine receptor 7	0	12	0	12
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	14	0	14
Histamine H3 receptor	0	3	2	5
Chain A, Ferritin light chain	18	0	0	18
acid sphingomyelinase	4	0	0	4
Smad3	26	0	0	26
NEDD8-activating enzyme E1 regulatory subunit isoform a	0	1	0	1
NEDD8-conjugating enzyme Ubc12	0	1	0	1
histone acetyltransferase KAT2A isoform 1	32	0	0	32
Potassium channel subfamily K member 2	0	5	4	9
Alpha-2B adrenergic receptor	0	12	5	17
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
Alpha-2C adrenergic receptor	0	12	5	17
Alpha-2A adrenergic receptor	0	12	5	17
Alpha-1A adrenergic receptor	0	7	7	21
Alpha-1B adrenergic receptor	0	6	5	16
Potassium channel subfamily K member 2	0	2	0	2
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	1	0	4
apical membrane antigen 1, AMA1	8	0	0	8
Beta-lactamase	0	1	0	5
Beta-lactamase	0	0	0	4
Metallo-beta-lactamase type 2	0	1	1	6
Metallo-beta-lactamase VIM-11	0	0	0	4
Metallo-beta-lactamase VIM-2	0	0	0	4
Beta-lactamase	0	0	0	4
Metallo-beta-lactamase	0	0	0	4
Beta-lactamase	0	1	0	5
DNA polymerase beta	10	0	0	10
DNA polymerase eta isoform 1	11	0	0	11
DNA polymerase iota isoform a (long)	31	0	0	31
DNA polymerase kappa isoform 1	23	0	0	23
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	10	0	10
Solute carrier family 15 member 1	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	5	0	5
Metallo-beta-lactamase VIM-13	0	0	0	4
Efflux transporter	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase Toho-1	0	0	0	4
Beta-lactamase	0	0	0	3
Class D beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	5	0	5
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-b-lactamase	0	0	0	5
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	5
Beta-lactamase class B VIM-2	0	1	1	7
Beta-lactamase VIM-1	0	0	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	19	0	0	19
MPI protein	0	1	0	1
thioredoxin glutathione reductase	17	0	0	17
hypothetical protein, conserved	6	0	0	6
alpha-galactosidase	7	0	0	7
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
cytochrome P450 2C19 precursor	12	0	0	12
perilipin-5	0	4	0	4
vitamin D3 receptor isoform VDRA	30	0	0	30
perilipin-1	0	4	0	4
importin subunit beta-1 isoform 1	13	0	0	13
snurportin-1	13	0	0	13
GTP-binding nuclear protein Ran isoform 1	9	0	0	9
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	4	0	4
caspase-1 isoform alpha precursor	7	0	0	7
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	7	0	7
Aurora kinase A	0	2	0	2
Rap guanine nucleotide exchange factor 3	11	0	0	11
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	10	0	10
Dual specificity protein kinase TTK	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	6	0	6
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	6	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	8	0	8
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	7	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	10	0	10
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	11	0	11
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	8	0	8
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	12	0	12
Aurora kinase B	0	2	0	2
Inner centromere protein	0	2	0	2
glucocerebrosidase	11	0	0	11
Atrial natriuretic peptide receptor 3	0	2	0	2
Type-1A angiotensin II receptor	0	6	4	10
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	7	1	8
Type-1 angiotensin II receptor	0	7	5	14
Type-2 angiotensin II receptor	0	7	1	8
Type-2 angiotensin II receptor	0	5	0	5
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	1	3
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Vasopressin V2 receptor	0	3	2	6
Oxytocin receptor	0	3	3	6
Vasopressin V1a receptor	0	1	3	4
Vasopressin V1a receptor	0	6	3	9
Vasopressin V1b receptor	0	2	2	4
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	2	1	4
Translocator protein	0	1	0	2
Oxytocin receptor	0	2	1	3
Vasopressin V2 receptor	0	2	1	3
Chain A, Hyaluronidase, phage associated	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	4	0	0	4
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	2	0	4
Glutamate receptor ionotropic, NMDA 1	0	4	1	8
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	4	1	8
Glutamate receptor ionotropic, NMDA 2C	0	4	1	9
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, NMDA 2D	0	4	1	8
Glutamate receptor ionotropic, NMDA 3B	0	4	1	8
Glutamate receptor ionotropic, NMDA 3A	0	4	1	8
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	4
Prostaglandin G/H synthase 2	0	3	0	4
Epidermal growth factor receptor	0	11	0	11
Fatty acid-binding protein, liver	0	4	1	5
Myeloperoxidase	0	3	0	3
Prostaglandin G/H synthase 1	0	4	0	5
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	7	0	7
Substance-P receptor	0	2	0	4
Prostaglandin G/H synthase 2	0	9	1	10
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	14	1	1	16
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	4	1	5
Caspase-7	6	0	0	6
caspase-3	6	0	0	6
Solute carrier organic anion transporter family member 2B1	0	4	0	5
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Insulin receptor	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	11	0	16
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	13	1	15
Solute carrier organic anion transporter family member 1B1	0	14	0	20
Atrial natriuretic peptide receptor 1	0	1	1	2
Atrial natriuretic peptide receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	2	2
Muscarinic acetylcholine receptor M1	0	0	1	3
Muscarinic acetylcholine receptor M4	0	2	1	4
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
P53	2	0	0	2
activating transcription factor 6	32	0	0	32
peripheral myelin protein 22 isoform 1	22	0	0	22
hemoglobin subunit beta	3	0	0	3
M-phase phosphoprotein 8	20	0	0	20
Bile salt export pump	0	20	0	20
Protein-arginine deiminase type-4	0	5	0	5
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	15	0	0	15
beta-2 adrenergic receptor	6	0	0	6
Caspase-7	6	0	0	6
Nuclear receptor subfamily 1 group I member 2	0	1	5	6
Endothelin receptor type B	1	1	0	2
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	1	2	1	4
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
Endothelin-1 receptor	0	1	0	1
Angiotensin-converting enzyme	0	8	1	10
B2 bradykinin receptor	0	1	0	1
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	9	0	0	9
Cholinesterase	0	9	0	9
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	7	2	9
Replicase polyprotein 1ab	0	13	3	16
Amine oxidase [flavin-containing] A	0	4	0	4
Acetylcholinesterase	0	13	0	13
Amine oxidase [flavin-containing] B	0	5	0	5
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2b	0	3	0	5
Adenosine receptor A2b	0	5	0	7
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	3	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	4	1	5
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	3	0	3
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Prothrombin	0	1	1	2
Neprilysin	0	1	0	1
Neprilysin	0	2	0	2
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	4	0	4
Angiotensin-converting enzyme	0	4	0	4
Beta-lactamase TEM	0	2	0	5
Beta-lactamase	0	2	0	4
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	4	2	6
bromodomain adjacent to zinc finger domain 2B	22	0	0	22
lysosomal alpha-glucosidase preproprotein	10	0	0	10
histone-lysine N-methyltransferase 2A isoform 2 precursor	8	0	0	8
Toll-like receptor 4	0	1	0	1
Solute carrier family 22 member 2	0	7	0	9
Amyloid-beta precursor protein	1	4	0	5
Neuronal acetylcholine receptor subunit alpha-4	5	4	2	12
Neuronal acetylcholine receptor subunit beta-2	5	4	2	12
UDP-glucuronosyltransferase 1A1	0	4	0	5
Potassium channel subfamily K member 10	0	1	0	1
Cytochrome P450 1B1	0	3	0	3
Multidrug and toxin extrusion protein 1	0	15	0	15
Solute carrier family 22 member 6	0	6	0	8
Solute carrier family 22 member 7	0	3	0	5
Solute carrier family 22 member 8	0	8	0	10
Solute carrier family 22 member 11	0	4	0	7
Solute carrier family 22 member 8	0	5	0	6
Solute carrier family 22 member 7	0	3	0	5
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	3
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase VIM-19	0	0	0	3
Beta-lactamase	0	0	0	3
Albumin	0	5	9	16
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	4
Beta-lactamase	0	0	0	4
B2 metallo-beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
BlaVIM-1	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 22 member 5	0	1	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase OXA-10	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	3
Beta-lactamase IMP-1	0	0	0	3
Beta-lactamase	0	0	0	3
nonstructural protein 1	16	0	0	16
pyruvate kinase	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	7	0	0	7
DNA dC->dU-editing enzyme APOBEC-3F isoform a	4	0	0	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Dihydrofolate reductase	0	6	0	6
Pancreatic triacylglycerol lipase	0	1	0	1
Pancreatic alpha-amylase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tumor necrosis factor receptor superfamily member 1A	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Quinone oxidoreductase	0	0	0	2
Stromal cell-derived factor 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Sortase A	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	29	0	0	29
streptokinase A precursor	0	0	4	4
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	3	1	4
30S ribosomal protein S7	0	3	1	4
50S ribosomal protein L15	0	3	1	4
50S ribosomal protein L10	0	3	1	4
50S ribosomal protein L11	0	3	1	4
50S ribosomal protein L7/L12	0	3	1	4
50S ribosomal protein L19	0	3	1	4
50S ribosomal protein L1	0	3	1	4
50S ribosomal protein L20	0	3	1	4
50S ribosomal protein L27	0	3	1	4
50S ribosomal protein L28	0	3	1	4
50S ribosomal protein L29	0	3	1	4
50S ribosomal protein L31	0	3	1	4
50S ribosomal protein L31 type B	0	3	1	4
50S ribosomal protein L32	0	3	1	4
50S ribosomal protein L33	0	3	1	4
50S ribosomal protein L34	0	3	1	4
50S ribosomal protein L35	0	3	1	4
50S ribosomal protein L36	0	3	1	4
30S ribosomal protein S10	0	3	1	4
30S ribosomal protein S11	0	3	1	4
30S ribosomal protein S12	0	3	1	4
30S ribosomal protein S13	0	3	1	4
30S ribosomal protein S16	0	3	1	4
30S ribosomal protein S18	0	3	1	4
30S ribosomal protein S19	0	3	1	4
30S ribosomal protein S20	0	3	1	4
30S ribosomal protein S2	0	3	1	4
30S ribosomal protein S3	0	3	1	4
30S ribosomal protein S4	0	3	1	4
30S ribosomal protein S5	0	3	1	4
30S ribosomal protein S8	0	3	1	4
30S ribosomal protein S9	0	3	1	4
50S ribosomal protein L13	0	3	1	4
50S ribosomal protein L14	0	3	1	4
50S ribosomal protein L16	0	3	1	4
50S ribosomal protein L23	0	3	1	4
30S ribosomal protein S15	0	3	1	4
50S ribosomal protein L17	0	3	1	4
50S ribosomal protein L21	0	3	1	4
50S ribosomal protein L30	0	3	1	4
50S ribosomal protein L6	0	3	1	4
30S ribosomal protein S14	0	3	1	4
30S ribosomal protein S17	0	3	1	4
30S ribosomal protein S1	0	3	1	4
50S ribosomal protein L18	0	3	1	4
50S ribosomal protein L2	0	3	1	4
50S ribosomal protein L3	0	3	1	4
50S ribosomal protein L24	0	3	1	4
50S ribosomal protein L4	0	3	1	4
50S ribosomal protein L22	0	3	1	4
50S ribosomal protein L5	0	3	1	4
30S ribosomal protein S21	0	3	1	4
50S ribosomal protein L25	0	3	1	4
50S ribosomal protein L36 2	0	3	1	4
Methionine--tRNA ligase, mitochondrial	0	0	1	1
ORF73	0	0	1	1
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	3
Adenylate cyclase type 1	0	2	0	2
Spike glycoprotein	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	2	2	4
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Major prion protein	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Major prion protein	0	0	1	1
Procathepsin L	0	3	2	5
5-hydroxytryptamine receptor 1A	0	5	0	5
Replicase polyprotein 1a	0	5	2	7
Replicase polyprotein 1ab	0	3	2	5
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	3	1	4
Polyunsaturated fatty acid lipoxygenase ALOX15	0	13	0	13
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	4	0	4
D(3) dopamine receptor	0	6	0	6
D(2) dopamine receptor	0	1	0	1
Proteasome subunit beta type-1	0	0	0	1
Adenylate cyclase type 3	0	2	0	2
Alpha-1D adrenergic receptor	0	16	5	22
Sodium-dependent dopamine transporter	0	6	0	6
D(1B) dopamine receptor	0	3	0	3
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	4	0	4
D(4) dopamine receptor	0	3	0	3
Histamine H1 receptor	0	2	3	6
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
5-hydroxytryptamine receptor 7	0	3	1	4
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Cytochrome P450 2J2	0	14	0	14
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	2	3
Calmodulin	0	1	3	4
Aldehyde oxidase 1	0	1	0	1
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Aldehyde oxidase	0	3	0	5
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
D	0	1	0	1
Proteasome subunit beta type-7	0	0	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	2
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	0	6	6
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Hypoxia-inducible factor 1-alpha	0	1	2	3
Endothelial PAS domain-containing protein 1	0	1	2	3
Solute carrier family 22 member 3	0	3	0	5
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 1	0	10	0	14
Solute carrier family 22 member 2	0	9	0	10
endonuclease IV	15	0	0	15
Glucocorticoid receptor	0	20	3	28
Glycine receptor subunit alpha-1	0	20	0	20
Glycine receptor subunit beta	0	20	0	20
Glycine receptor subunit alpha-2	0	20	0	20
Glycine receptor subunit alpha-3	0	20	0	20
Potassium voltage-gated channel subfamily A member 1	0	2	1	3
glycogen synthase kinase-3 alpha	0	0	0	1
Exportin-1	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	2	0	4
Aldo-keto reductase family 1 member B1	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	4
UDP-glucuronosyltransferase 1-6	0	2	0	2
Cytochrome P450 2A5	0	1	0	2
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	3	0	3
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
UDP-glucuronosyltransferase 2B10	0	2	0	2
Beta-secretase 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Zn finger protein	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	3
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	1	2	3
Phosphodiesterase	0	5	0	5
Multidrug resistance-associated protein 5	0	1	0	2
Glutathione S-transferase P	0	2	0	2
Alpha-tocopherol transfer protein	0	0	1	1
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Alpha-synuclein	4	4	0	8
G-protein coupled bile acid receptor 1	0	0	2	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	4
Multidrug resistance-associated protein 1	0	3	1	6
Solute carrier organic anion transporter family member 1A2	0	1	0	5
Solute carrier organic anion transporter family member 1A3	0	1	0	4
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Vascular endothelial growth factor receptor 2	0	2	0	2
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	1	1	0	2
phosphoglycerate kinase	4	0	0	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	3	0	0	3
Gamma-aminobutyric acid	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	6	0	6
Gamma-aminobutyric acid receptor subunit delta	0	6	0	6
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	7	4	11
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	7	2	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	7	1	8
Translocator protein	0	1	0	1
Translocator protein	0	2	0	2
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-3	0	7	1	8
Gamma-aminobutyric acid receptor subunit alpha-2	0	7	1	8
Gamma-aminobutyric acid receptor subunit beta-2	0	7	2	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	6	0	6
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit theta	0	6	0	6
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
high affinity choline transporter 1 isoform a	0	1	0	1
Estrogen receptor	0	6	2	8
Estrogen-related receptor gamma	0	0	1	1
Disintegrin and metalloproteinase domain-containing protein 17	6	0	0	6
UDP-glucose 4-epimerase	0	2	0	2
Mitogen-activated protein kinase 14	0	1	0	1
Estrogen receptor beta	0	5	2	7
Cysteinyl leukotriene receptor 1	0	2	0	2
STAT3, partial	0	3	0	3
NPC intracellular cholesterol transporter 1 precursor	7	0	0	7
signal transducer and activator of transcription 1-alpha/beta isoform alpha	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	5	0	6
Sodium/potassium-transporting ATPase subunit beta-1	0	5	0	6
Sodium/potassium-transporting ATPase subunit alpha-3	0	3	0	4
Sodium/potassium-transporting ATPase subunit beta-2	0	3	0	4
Sodium/potassium-transporting ATPase subunit alpha-2	0	5	0	6
Sodium/potassium-transporting ATPase subunit alpha-1	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-3	0	3	0	4
Sodium/potassium-transporting ATPase subunit gamma	0	3	0	4
Sodium/potassium-transporting ATPase subunit alpha-4	0	3	0	4
Solute carrier organic anion transporter family member 4C1	0	2	0	5
PAX8	0	0	0	3
tumor necrosis factor	4	0	0	4
Sodium/potassium-transporting ATPase subunit alpha-2	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-3	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-1	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-4	0	3	0	3
Solute carrier organic anion transporter family member 4C1	0	0	0	2
Solute carrier organic anion transporter family member 1A4	0	0	0	1
ADP-ribose glycohydrolase MACROD2	0	1	0	1
Aspartate aminotransferase, cytoplasmic	0	2	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Glutamate receptor 1	2	0	0	2
Glutamate receptor 3	2	0	0	2
Glutamate receptor 4	2	0	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Thromboxane A2 receptor	0	2	1	4
Prostaglandin E2 receptor EP1 subtype	0	1	3	4
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	1	3
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	1	2	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin D2 receptor	0	1	2	3
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	2	0	2
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Histamine H4 receptor	0	2	2	4
eyes absent homolog 2 isoform a	3	0	0	3
Chain A, Breast cancer type 1 susceptibility protein	3	0	0	3
RGS12	1	0	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
DNA polymerase III, partial	1	0	0	1
isocitrate dehydrogenase 1, partial	3	0	0	3
LANA	0	0	0	1
thyrotropin-releasing hormone receptor	6	0	0	6
serine-protein kinase ATM isoform a	3	0	0	3
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	2	0	2
tumor susceptibility gene 101 protein	2	0	0	2
kelch-like ECH-associated protein 1	0	0	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	5	0	5
cGMP-specific 3',5'-cyclic phosphodiesterase	0	7	1	8
3',5'-cyclic-AMP phosphodiesterase	0	4	0	4
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	2	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	2	0	2
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	2	0	2
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	2	0	2
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	3	0	3
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	2	0	2
Exopolyphosphatase PRUNE1	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Rap guanine nucleotide exchange factor 4	2	0	0	2
Equilibrative nucleoside transporter 1	0	4	0	4
Single-stranded DNA cytosine deaminase	2	0	0	2
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	2	0	2
Phosphodiesterase	0	3	0	3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	3	0	4
mu-type opioid receptor isoform MOR-1	0	0	2	2
5-hydroxytryptamine receptor 2A	0	0	2	2
Tyrosine-protein kinase Lck	0	2	0	2
POU domain, class 2, transcription factor 1	0	0	0	5
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 9	0	1	0	1
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Lanosterol 14-alpha demethylase	0	3	0	3
Chain A, GLUTATHIONE TRANSFERASE A1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain B, Glutathione S-transferase P1-1	0	1	0	1
Nrf2	1	0	0	1
WRN	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
Hematopoietic prostaglandin D synthase	0	2	0	2
Glutathione S-transferase A1	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 6	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
14 kDa phosphohistidine phosphatase	0	2	0	2
large T antigen	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
Pantothenate synthetase	0	2	0	2
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
galanin receptor type 3	0	2	0	2
D(3) dopamine receptor isoform e	1	0	0	1
ClpP	2	0	0	2
Acetylcholinesterase	0	3	0	3
Pyruvate kinase PKM	0	1	0	1
Alpha-glucosidase MAL12	0	1	0	1
Hyaluronidase-1	0	1	0	1
Integrase	0	2	0	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Vpr	5	0	0	5
Solute carrier family 22 member 8	0	1	0	3
Thymidylate synthase	0	1	0	1
Aromatase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Beta-galactosidase	0	1	0	1
Lipopolysaccharide heptosyltransferase 1	0	1	0	1
PA-I galactophilic lectin	0	0	1	1
Jacalin	0	0	1	1
Liver carboxylesterase 1	0	2	0	4
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Plasma kallikrein	0	0	0	3
Macrophage migration inhibitory factor	0	5	0	5
Metabotropic glutamate receptor 5	0	2	1	3
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Parkin	7	0	0	7
pyruvate kinase PKM isoform b	2	0	0	2
N-glycosylase/DNA lyase	0	2	0	2
Ornithine decarboxylase	2	0	0	2
Lactoperoxidase	0	1	0	1
Hsf1 protein	0	0	3	3
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Stromelysin-1	0	1	1	2
Urease subunit alpha	0	2	0	2
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Urease subunit beta	0	2	0	2
Chain A, Purine-nucleoside Phosphorylase	0	1	0	1
Chain C, Xanthine dehydrogenase/oxidase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Prostacyclin receptor	0	1	1	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Peptide deformylase 1A, chloroplastic/mitochondrial	0	1	0	1
Peptide deformylase	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Androgen receptor	0	5	2	7
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	2	0	3
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
C-X-C chemokine receptor type 3	0	2	0	2
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain A, ADENOSINE DEAMINASE	0	1	0	1
Chain A, ADENOSINE DEAMINASE	0	1	0	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Purine nucleoside phosphorylase	0	0	0	1
Adenosylhomocysteinase	0	1	0	2
Adenosine deaminase	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Beta-1 adrenergic receptor	0	1	3	6
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
Beta-2 adrenergic receptor	0	4	1	7
Beta-1 adrenergic receptor	0	5	3	11
Beta-2 adrenergic receptor	0	1	1	2
Beta-adrenergic receptor kinase 1	0	0	3	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Beta-1 adrenergic receptor	0	2	1	3
Beta-2 adrenergic receptor	0	2	1	3
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	2	2
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	2	2
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	2	2
Taste receptor type 2 member 13	0	0	2	2
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	2	2
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	2	2
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2	0	0	1	1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	0	0	1	1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	0	0	1	1
Cytochrome P450 1A1	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Intestinal-type alkaline phosphatase	0	4	0	4
Large neutral amino acids transporter small subunit 1	0	4	0	5
Phospholipase A-2-activating protein	0	4	0	4
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
5'-nucleotidase	0	2	0	2
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
SLC16A10 protein	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Potassium channel subfamily K member 3	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 2 subunit alpha	0	5	0	5
Sodium channel protein type 3 subunit alpha	0	4	0	4
Potassium voltage-gated channel subfamily A member 5	0	3	0	3
Potassium voltage-gated channel subfamily D member 2	0	2	0	2
Potassium channel subfamily K member 18	0	1	0	1
Type-1 angiotensin II receptor	0	2	1	3
Platelet glycoprotein VI	0	1	1	3
Type-1 angiotensin II receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	1	0	1
PINK1	1	0	0	1
Kappa-type opioid receptor	0	5	1	9
Mu-type opioid receptor	0	5	1	10
Multidrug transporter MdfA	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldehyde oxidase 1	0	1	0	1
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	2
estrogen receptor beta isoform 1	0	3	0	3
Cystathionine gamma-lyase	0	2	0	2
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
TSHR protein	2	0	0	2
Apoptotic peptidase activating factor 1	0	1	0	1
luciferase	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Glutathione reductase	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	4
Glycoprotein hormones alpha chain	2	0	0	2
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	2	0	3
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Serine racemase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	3	3
Proteinase-activated receptor 1	0	1	1	2
Kappa-type opioid receptor	0	4	4	9
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	3	3
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	1	1	3
Phospholipase A2, membrane associated	0	0	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
C-terminal-binding protein 1	1	0	0	1
Leukotriene B4 receptor 1	0	0	0	1
Myosin light chain kinase, smooth muscle	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Leukotriene B4 receptor 2	0	0	0	1
Sodium/iodide cotransporter	0	1	0	1
G-protein coupled receptor 55	0	1	0	1
Platelet-activating factor receptor	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)	0	1	0	1
Chain L, Igg2b-kappa 40-50 Fab (light Chain)	0	1	0	1
Chain A, Na, K-ATPase alpha subunit	0	0	1	1
Kruppel-like factor 5	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Oxytocin receptor	0	0	1	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
Vascular endothelial growth factor receptor 1	0	1	0	1
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
vasopressin V1b receptor	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Tumor necrosis factor	0	1	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Cytochrome P450 2D26	0	2	0	2
Cytochrome P450 2D3	0	2	0	2
Cytochrome P450 2D4	0	2	0	2
Alpha-1A adrenergic receptor	0	1	2	3
Alpha-1A adrenergic receptor	0	3	1	4
Alpha-1B adrenergic receptor	0	4	0	4
Nischarin	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Alpha-1B adrenergic receptor	0	0	1	1
Alpha-2B adrenergic receptor	0	1	0	2
Alpha-2C adrenergic receptor	0	1	0	2
Alpha-2A adrenergic receptor	0	1	0	2
Phenylethanolamine N-methyltransferase	0	0	0	1
Dihydrofolate reductase	0	2	0	2
Sodium/potassium/calcium exchanger 4	0	1	1	2
Sodium/potassium/calcium exchanger 2	0	1	1	2
Renin	0	1	0	1
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
interferon gamma precursor	0	0	0	1
Beta-casein	0	1	0	1
Interstitial collagenase	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
5-hydroxytryptamine receptor 1B	0	4	1	5
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
luciferase	0	0	0	1
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Chloroquine resistance transporter	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Nuclear receptor subfamily 2 group E member 1	0	0	3	3
Monocarboxylate transporter 4	0	1	0	2
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Multidrug resistance protein 1a	0	0	0	1
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	0	2
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
Riboflavin-binding protein	0	1	1	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
BRCA1	2	0	0	2
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Protein argonaute-2	0	0	1	1
Prolyl 4-hydroxylase, beta polypeptide	0	0	0	1
interleukin-8 isoform 1 precursor	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	1	2
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Acetylcholinesterase	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
RAD51	0	1	0	1
Cocaine esterase	0	2	0	2
Lysine-specific histone demethylase 1A	0	1	0	1
Polycomb protein EED	0	1	0	1
Estrogen receptor	0	0	1	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
Polycomb protein SUZ12	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
Estrogen receptor beta	0	0	1	1
Protease	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	2	1	3
Stromal interaction molecule 1	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
Dihydroorotate dehydrogenase (quinone), mitochondrial	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
hexokinase	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Tat	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Tryptophan 5-hydroxylase 1	0	1	0	1
Cathepsin D	0	1	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Transthyretin	0	1	0	3
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
chaperonin GroEL	1	0	0	1
Trace amine-associated receptor 1	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, PAPAIN	1	0	0	1
putative alpha-glucosidase	1	0	0	1
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
Cathepsin G	0	1	0	1
Cyclin-dependent kinase 4	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Casein kinase I isoform alpha	0	1	0	1
Casein kinase I isoform delta	0	1	0	1
Casein kinase I isoform epsilon	0	1	0	1
Pteridine reductase 1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
Ricin	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,235)

Protein Targets (1,763)

Cor Pulmonale

Synonyms(7)

Research Excerpts

Overview

Context

Treatment

Research

Studies (1,235)

Drugs Studied (446)

Protein Targets (1,763)