A disease due to deficiency of NIACIN, a B-complex vitamin, or its precursor TRYPTOPHAN. It is characterized by scaly DERMATITIS which is often associated with DIARRHEA and DEMENTIA (the three D's).
| Excerpt | Reference |
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| "Although pellagra is still common in some parts of the world, it is now rare in North America." | ( DesGroseilliers, JP; Shiffman, NJ, 1976) |
| "A case of pellagra is described that occurred in a patient with an eating disorder and who presented with marked photosensitivity and diarrhoea." | ( Judd, LE; Poskitt, BL, 1991) |
| "Clinical pellagra is a multiple vitamin-deficiency disease." | ( Hendricks, WM, 1991) |
| "Pellagra is a classical disease rarely seen in this country." | ( Degos, CF; Séréni, C, 1990) |
| "Pellagra is the result of increased viscosity of extracellular matrix (ECM)." | ( Stone, OJ, 1993) |
| "Pellagra is caused by a deficiency of nicotinamide or of its precursor tryptophan." | ( Pasmans, SG; Preesman, AH; van Vloten, WA, 1998) |
| "Although pellagra is a recognized complication of isoniazid therapy, the diagnosis may be overlooked or delayed--sometimes with life-threatening consequences." | ( Basarab, T; Darvay, A; McGregor, JM; Russell-Jones, R, 1999) |
| "Pellagra is a systemic disorder caused by severe niacin deficiency." | ( Kombate, K; Pitche, P; Tchangai-Walla, K, 1999) |
| "Pellagra is a nutritional disease with cutaneous, gastrointestinal, and neuropsychiatric manifestations." | ( Kertesz, SG, 2001) |
| "Pellagra is clinically manifested by a photosensitive dermatitis, diarrhea, and dementia." | ( Akpolat, I; Aydin, M; Cantürk, MT; Koca, R; Küçüködük, S; Oztürk, F, 2001) |
| "Pellagra is a nutritional wasting disease attributable to a combined deficiency of tryptophan and niacin (nicotinic acid)." | ( Prousky, JE, 2003) |
| "Diagnosis of pellagra is difficult in the absence of the skin lesions, and is often facilitated by the presence of characteristic ones." | ( Hegyi, J; Hegyi, V; Schwartz, RA, 2004) |
| "Pellagra is caused by nicotinic acid deficiency; it is rarely encountered in developed countries, and it is mainly related to poverty and malnutrition, as well as with chronic alcoholism." | ( Andreou, C; Bascialla, F; Bozikas, VP; Karavatos, A; Pitsavas, S, 2004) |
| "Pellagra is an exceptional disorder in France." | ( Fontès, V; Guitton-Oudet, E; Karsenti, D; Lorette, G; Machet, L; Machet, MC; Wierzbicka, E, 2005) |
| "At present, pellagra is encountered most often in patients with chronic alcoholism, which is called APE." | ( Fukuhara, N; Nakajima, T; Sakai, K, 2006) |
| "Pellagra is a curable dietary illness that unchecked leads to dementia, diarrhoea, dermatitis and death due to lack of the precursors for NAD(H)." | ( Ramsden, DB; Williams, AC, 2007) |
| "Pellagra is a potentially fatal, nutritional disease with cutaneous, gastrointestinal, and neuropsychiatric manifestations." | ( Brzozowska, A; Jagielska, G; Tomaszewicz-Libudzic, EC, 2007) |
| "However, cases of pellagra are recently reported in West Europe, USA, Australia, and Japan in connection with chronic alcoholism, gastrointestinal malabsorption, and some medications." | ( Cholongitas, E; Ioannidou, D; Pipili, C, 2008) |
| "Pellagra is a rare clinical syndrome caused by niacin deficiency, and although most commonly nutritional in origin, may be secondary to carcinoid syndrome." | ( Reichman, O; Sobel, JD, 2009) |
| "Pellagra is a nutritional disease caused by the deficiency of niacin." | ( Azevedo, F; Duarte, AF; Magina, S; Nogueira, A, 2009) |
| "Pellagra is the clinical manifestation of niacin deficiency." | ( Hammond, N, 2011) |
| "Pellagra is characterized by dermatitis, diarrhea, dementia and eventually death occurring as a result of niacin or its precursor tryptophan deficiency." | ( Altun, F; Bilgili, SG; Calka, O; Karadag, AS, 2011) |
| "Pellagra is a nutritional disease caused by the deficiency of niacin." | ( Fernandes, IC; Oliveira, A; Pinto-Almeida, T; Rosmaninho, A; Sanches, M; Selores, M; Vilaça, S, 2012) |
| "Pellagra is the clinical presentation of niacin deficiency comprising cutaneous, gastrointestinal and neuropsychiatric manifestations." | ( Chidlovskii, E; Couturier, P; Deschasse, G; Tahar, A, 2012) |
| "Pellagra is a disease of poverty that is treatable but easily overlooked." | ( Chamdula, A; Frank, GP; Koop, K; van Oosterhout, JJ; Voorend, DM, 2012) |
| "Pellagra is caused by a deficiency of niacin." | ( Balasubramanian, R; Kavitha, B; Kumar, T, 2012) |
| "Pellagra is a nutritional disease caused by the deficiency of niacin." | ( Ahmed, S; Farah, J; Haykel, B; Houcine, M; Khouloud, B; Yacine, BS; Zoubeir, BS, 2013) |
| "Although endemic pellagra is virtually eradicated in Western countries, it continues to present as pellagrous encephalopathy in patients with risk factors for malnutrition such as chronic alcohol intake, homelessness, or AIDS." | ( Ivkovic, A; Oldham, MA, 2012) |
| "Pellagra is a rare condition that has been known for many years to be related to niacin deficiency." | ( Belghith, I; Ben Osman, A; El Euch, D; Fillali, A; Karoui, S; Mokni, M; Zaraa, I, 2013) |
| "Pellagra is a complex systemic disease resulting from inadequate dietary intake of coenzyme precursors nicotinamide and tryptophan." | ( Cavanna, AE; Nani, A; Williams, AC, 2013) |
| "Pellagra is caused by deficiency of niacin or its precursor tryptophan." | ( Aydin, F; Cengiz, N; Onar, MK; Pancar Yuksel, E; Sen, N; Sen, S; Senturk, N, 2014) |
| "In addition, pellagra is mediated through prostaglandin E₂-EP4 (PGE₂-EP4) signaling via reactive oxygen species (ROS) production in keratinocytes." | ( Ikenouchi-Sugita, A; Sugita, K, 2015) |
| "Pellagra is a disorder characterized by dermatitis, diarrhea, dementia and eventually death, resulting from a deficiency of niacin or its precursor tryptophan." | ( Gupta, Y; Shah, I, 2015) |
| "The conquest of pellagra is commonly associated with one name: Joseph Goldberger of the US Public Health Service, who in 1914 went south, concluded within 4 months that the cause was inadequate diet, spent the rest of his life researching the disease, and--before his death from cancer in 1929--found that brewer's yeast could prevent and treat it at nominal cost." | ( Bryan, CS; Mull, SR, 2015) |
| "AbstractPellagra is a deficiency of niacin or its amino acid precursor, tryptophan, which presents with the classic four Ds: the characteristic dermatitis, diarrhea, dementia, and eventually death if left untreated." | ( Dunn, SH; Matapandeu, G; Pagels, P, 2017) |
| "Pellagra is a nutrient deficiency disease caused by insufficient niacin levels." | ( Izaki, S; Kanazawa, N; Miyagi, T; Sogabe, Y; Takahashi, K; Uezato, H; Utani, A; Yamaguchi, S; Yasuda, M, 2017) |
| "Pellagra is an acute medical condition, frequently encountered in the context of alcohol dependence and poverty." | ( Benegal, V; Chand, PK; Ganesh, S; Kandasamy, A; Mukherjee, D; Murthy, P; Narasimha, VL; Reddy, S; Shukla, L, 2019) |
| "Pellagra is a type of dietary deficiency disease caused by an insufficiency of niacin or tryptophan." | ( Yamamoto, Y, 2019) |
| "Pellagra is a nutritional disorder of niacin deficiency which is characterized by triad of dermatitis, diarrhea and dementia." | ( Chinyere, A; Emmanuel, P; Hirayama, K; Manchan, DB; Onimisi, OE; Usman, AB; Yakubu, M, 2019) |
| "Pellagra is a clinical syndrome caused by a deficiency of niacin (nicotinic acid) and/or its precursor tryptophan." | ( Dawe, RS; Mponda, K; Prabhu, D, 2021) |
| "Introduction: pellagra is a systemic disease due to deficiency of vitamin B3 or tryptophan, its precursor." | ( López, D; Otero, G, 2021) |
| "Pellagra is a nutritional deficiency disease associated with niacin (vitamin B3) deficiency." | ( Bipath, P; Tosh, C; Viljoen, M, 2021) |
| "Pellagra is characterized by "dermatitis - diarrhea - dementia - death"." | ( Flamm, H, 2021) |
| "Pellagra is a rare disease caused by niacin deficiency or a disruption of its metabolism." | ( Hołubiec, P; Jaworek, AK; Leończyk, M; Staszewski, F; Wojas-Pelc, A; Łazarczyk, A, 2021) |
| "Pellagra is caused by niacin (vitamin B3) deficiency and patients with pellagra present with a characteristic rash." | ( Auld, AF; Buono, N; Chilikutali, L; Chisuwo, L; Chiwaula, MJ; da Silva, R; Girma, B; Gunde, LJ; Gutreuter, S; Jahn, A; Kalua, T; Kaunda, E; Kim, EJ; Kumwenda, T; Maida, A; Maphosa, T; Marshall, RE; Mbewe, K; Mekonnen, TF; Melgar, M; Mhango, V; Moffitt, A; Mponda, K; Mtoto, F; Muula, AS; Mwamale, S; Mwenyeheri, G; Nabity, SA; Nagoli, E; Ngongonda, D; Nyirenda, R; Odo, M; Oeltmann, JE; Sharma, AJ; Sunguti, J; Surie, D; Williams, AM; Woelk, G; Zimba, SB, 2022) |
| "Pellagra is rarely manifested as a full 3D spectrum, with only one or two characteristics, which lack diagnostic specificity, especially in individuals with alcoholism." | ( Chen, X; Du, C; Jiang, G; Yang, C, 2022) |
| "Pellagra is a nutritional disease resulting from a deficiency of vitamin B3 (niacin) primarily due to corn consumption, especially in developing countries, but in developed countries, it can occur secondarily as a consequence of chronic alcoholism, malabsorption, certain drugs, and bariatric surgery." | ( Hassan, HS; Pandu, SM; Said, SS, 2023) |
| "Pellagra is a nutritional disease resulting from a deficiency of vitamin B3 (niacin) primarily due to corn consumption, especially in developing countries, but in developed countries, it can occur secondarily as a consequence of chronic alcoholism, malabsorption, certain drugs, and bariatric surgery." | ( Hassan, HS; Pandu, SM; Said, SS, 2023) |