Page last updated: 2024-09-27

Barotrauma

Injury following pressure changes; includes injury to the eustachian tube, ear drum, lung and stomach.

Synonyms(1)

Synonym
Barotrauma

Research Excerpts

Overview

ExcerptReference
"Barotrauma is the most effective mechanism inducing acute lung inflammation and GR alpha overexpression."( Bertorelli, G; Bobbio, A; Carbognani, P; Corradi, A; Maria Cantoni, A; Mergoni, M; Pesci, A; Peveri, S; Rusca, M; Tincani, G, 2008)
"Barotrauma is a common complication of diving, typically occurring at depths greater than 30 m (98."( Bridwell, RE; Cibrario, A; Goss, S; Inman, BL; Oliver, JJ, 2022)

Treatment

ExcerptReference
"Among 127 patients with ARDS treated with ECMO, barotrauma occurred in 24 (18."( Bai, Y; Chen, S; Huang, X; Li, M; Xia, J; Zhan, Q; Zhang, Z, 2023)

Research

Studies (220)

TimeframeStudies, This Condition (%)All Conditions %
pre-199052 (23.64)23.3326
1990's49 (22.27)12.5806
2000's46 (20.91)18.1394
2010's60 (27.27)28.8240
2020's13 (5.91)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carnitine0low10
chlorine0low10
hydrogen carbonate0low10
hydrogen0low10
nitrous oxide0low70
n-methyl-3,4-methylenedioxyamphetamine0low10
acetazolamide0low10
albuterol0low10
antipyrine0low30
benzocaine0low10
betahistine0low10
chloral hydrate0low10
chlorpromazine0low10
diazepam0low10
furosemide0low10
gentamicin0medium11
guaifenesin0low10
halothane0low20
lidocaine0low10
isoflurane0low20
isoproterenol0low20
edaravone0low20
methyl parathion0low20
apnea0low120
oxymetazoline0medium32
pantoprazole0low10
potassium chloride0low10
sevoflurane0medium11
sulfinpyrazone0low10
prednisolone0low10
hydroxyproline0low10
thyroxine0low10
spironolactone0low10
methoxamine0low10
methylene blue0low10
methacholine chloride0low10
methylprednisolone0low10
ephedrine0medium43
aminophylline0low10
fluorescein0low10
lanthanum0low10
technetium0low10
titanium0low10
gold0low10
helium0low30
uranium0low10
tricalcium phosphate0low10
zinc phosphate0low20
4-methoxyamphetamine0low10
substance p0low10
propiconazole0low70
fomesafen0low10
remifentanil0low10
xenon radioisotopes0low10
nicotine0low10
fibrinogen0low10
technetium tc 99m hydroxymethylene diphosphonate0low10
heliox0low10
atropine0low10
cortisone0low10
inositol 3-phosphate0low10
oleic acid0low20
cocaine0low30
prinomastat0low10
thiopental0low10
humulene0low10
4-hydroxy-2-nonenal0low10
phenylephrine hydrochloride0low90
silicon0low10
radium0low40
amoxicillin-potassium clavulanate combination0low10
cefdinir0low10
technetium tc 99m exametazime0low10
scopolamine hydrobromide0low10
piperidines0low10
tetracycline0low10
piroxicam0medium11
mobiflex0medium11
transforming growth factor beta0low10
technetium tc 99m sulfur colloid0low10
bassianolide0low30
technetium tc 99m medronate0low10
thromboplastin0low10
deoxyguanosine0low10
sildenafil citrate0low10
8-hydroxy-2'-deoxyguanosine0low10

Protein Targets (931)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Microtubule-associated protein tau160016
vitamin D3 receptor isoform VDRA9009
Transient receptor potential cation channel subfamily A member 10011
5-hydroxytryptamine receptor 2C0628
5-hydroxytryptamine receptor 2A0628
5-hydroxytryptamine receptor 1A09413
5-hydroxytryptamine receptor 1B07310
5-hydroxytryptamine receptor 1D0336
5-hydroxytryptamine receptor 1F0336
5-hydroxytryptamine receptor 2B0628
5-hydroxytryptamine receptor 60123
Sodium-dependent serotonin transporter0628
Sodium-dependent serotonin transporter0618
5-hydroxytryptamine receptor 7 0224
5-hydroxytryptamine receptor 5A0123
5-hydroxytryptamine receptor 5B0123
5-hydroxytryptamine receptor 3A0123
5-hydroxytryptamine receptor 4 0123
5-hydroxytryptamine receptor 3B0123
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase3003
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
thioredoxin reductase170017
GALC protein3003
GLI family zinc finger 3190019
nuclear receptor subfamily 1, group I, member 3200020
cytochrome P450 family 3 subfamily A polypeptide 4140014
glucocorticoid receptor [Homo sapiens]200020
retinoic acid nuclear receptor alpha variant 1190019
retinoid X nuclear receptor alpha130013
estrogen-related nuclear receptor alpha240024
Carbonic anhydrase 0101
Carbonic anhydrase 0101
arylsulfatase A6006
Carbonic anhydrase0101
euchromatic histone-lysine N-methyltransferase 2180018
Bloom syndrome protein isoform 18008
thyroid hormone receptor beta isoform a7007
nuclear factor erythroid 2-related factor 2 isoform 1200020
geminin200020
peripheral myelin protein 229009
survival motor neuron protein isoform d7007
muscleblind-like protein 1 isoform 14004
Gamma-aminobutyric acid receptor subunit pi114116
ATP-binding cassette sub-family C member 3017017
Multidrug resistance-associated protein 4017017
Carbonic anhydrase0101
Solute carrier family 22 member 60303
Carbonic anhydrase 120318
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump024024
Glycogen phosphorylase, muscle form0101
Renin0202
Carbonic anhydrase 106113
Carbonic anhydrase 206112
Carbonic anhydrase 20202
Cytochrome P450 1A20213
Carbonic anhydrase 30317
Cathepsin B0101
Cytochrome P450 3A40505
Steryl-sulfatase0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80101
Cytochrome P450 2D60416
Cytochrome P450 2A60415
Cytochrome P450 2C9 0707
Androgen receptor0607
Gamma-aminobutyric acid receptor subunit beta-1114116
Translocator protein0315
Gamma-aminobutyric acid receptor subunit delta114116
Gamma-aminobutyric acid receptor subunit gamma-2114116
Gamma-aminobutyric acid receptor subunit alpha-5114116
Gamma-aminobutyric acid receptor subunit alpha-3114116
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60101
Carbonic anhydrase 406110
Carbonic anhydrase 60317
Gamma-aminobutyric acid receptor subunit gamma-1114116
Gamma-aminobutyric acid receptor subunit alpha-2114116
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10303
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-4114116
Gamma-aminobutyric acid receptor subunit gamma-3114116
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-6114116
Adenosine receptor A2a0101
Delta-type opioid receptor0202
Cytochrome P450 2C190202
Delta-type opioid receptor0213
Mu-type opioid receptor0303
Carbonic anhydrase 5A, mitochondrial0419
Carbonic anhydrase0303
Kappa-type opioid receptor0101
Carbonic anhydrase 70317
Carbonic anhydrase0101
D(1A) dopamine receptor2103
Corticosteroid 11-beta-dehydrogenase isozyme 10202
Carbonic anhydrase0101
D(2) dopamine receptor0416
Gamma-aminobutyric acid receptor subunit alpha-1114116
Gamma-aminobutyric acid receptor subunit beta-3114116
Gamma-aminobutyric acid receptor subunit beta-2114116
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0202
Fatty-acid amide hydrolase 10202
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0314
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70427
Carbonic anhydrase 90419
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase 30101
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0101
Sigma intracellular receptor 20101
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10303
Renin0101
Carbonic anhydrase 0101
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130214
GABA theta subunit114116
Canalicular multispecific organic anion transporter 1016016
Carbonic anhydrase 40202
Carbonic anhydrase 150304
Acidic mammalian chitinase0101
Carbonic anhydrase 130306
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon114116
Carbonic anhydrase 0101
Carbonic anhydrase 140318
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0318
glp-1 receptor, partial9009
GLS protein7007
regulator of G-protein signaling 44004
estrogen nuclear receptor alpha280028
NPYLR7B0022
thyroid stimulating hormone receptor8008
flap endonuclease 16006
Beta-2 adrenergic receptor0449
Beta-1 adrenergic receptor0235
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Beta-3 adrenergic receptor0123
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
Beta-2 adrenergic receptor 0125
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Beta-2 adrenergic receptor0246
ATP-dependent phosphofructokinase8008
USP1 protein, partial100010
lamin isoform A-delta10150015
Solute carrier family 22 member 30101
Phenylethanolamine N-methyltransferase0202
Substance-P receptor0303
Cytochrome P450 2A50202
Sodium-dependent dopamine transporter0516
Sigma non-opioid intracellular receptor 10101
ATAD5 protein, partial9009
67.9K protein7007
peroxisome proliferator-activated receptor delta120012
chromobox protein homolog 1110011
nuclear factor erythroid 2-related factor 2 isoform 25005
Cytochrome P450 2J20606
Nicotinate phosphoribosyltransferase0202
TDP1 protein240024
D(1A) dopamine receptor3003
neuropeptide S receptor isoform A2002
Chain A, 2-oxoglutarate Oxygenase8008
AR protein220022
pregnane X nuclear receptor180018
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0304
5-hydroxytryptamine receptor 40606
Muscarinic acetylcholine receptor M206110
Muscarinic acetylcholine receptor M408111
Muscarinic acetylcholine receptor M107110
Muscarinic acetylcholine receptor M30518
Muscarinic acetylcholine receptor M40619
Muscarinic acetylcholine receptor M50518
Muscarinic acetylcholine receptor M507110
Muscarinic acetylcholine receptor M206211
Muscarinic acetylcholine receptor M106110
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30518
Alpha-1D adrenergic receptor0629
5-hydroxytryptamine receptor 2C0606
Muscarinic acetylcholine receptor M40202
Histamine H2 receptor5017
5-hydroxytryptamine receptor 70202
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0112
RAR-related orphan receptor gamma200020
G120012
aryl hydrocarbon receptor120012
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a120012
nuclear receptor ROR-gamma isoform 17007
cytochrome P450 3A4 isoform 1110011
Voltage-dependent calcium channel gamma-2 subunit8008
Interferon beta130013
HLA class I histocompatibility antigen, B alpha chain 120012
Glutamate receptor 28008
TAR DNA-binding protein 437007
Inositol hexakisphosphate kinase 1120012
ATPase family AAA domain-containing protein 57007
Ataxin-29009
cytochrome P450 2C9, partial120012
Histamine H3 receptor0101
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
cytochrome P450 2D68008
thyroid hormone receptor beta isoform 2130013
Cellular tumor antigen p53160016
Proteasome subunit beta type-110001
acetylcholinesterase7007
phosphopantetheinyl transferase8008
Fumarate hydratase2002
NFKB1 protein, partial2002
Thrombopoietin1001
Smad36006
caspase 7, apoptosis-related cysteine protease3003
estrogen receptor 2 (ER beta)100010
progesterone receptor120012
NADPH oxidase 10101
farnesoid X nuclear receptor9009
polyprotein2002
peroxisome proliferator activated receptor gamma160016
vitamin D (1,25- dihydroxyvitamin D3) receptor130013
Snq2p0001
caspase-33003
IDH17007
Adenylate cyclase type 1 0202
v-jun sarcoma virus 17 oncogene homolog (avian)8008
Histone H2A.x7007
Caspase-71001
Spike glycoprotein0112
Replicase polyprotein 1ab0112
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a2002
potassium voltage-gated channel subfamily H member 2 isoform d6006
caspase-31001
histone deacetylase 9 isoform 32002
heat shock protein beta-19009
mitogen-activated protein kinase 15005
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 12002
DNA polymerase kappa isoform 17007
M-phase phosphoprotein 82002
histone acetyltransferase KAT2A isoform 17007
muscarinic acetylcholine receptor M15005
lethal factor (plasmid)3003
Proteasome subunit alpha type-70001
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Transmembrane protease serine 20112
Glutamate receptor ionotropic, NMDA 2D0101
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Bile salt export pump0303
Potassium channel subfamily K member 20202
Epidermal growth factor receptor0101
Albumin0225
Albumin0022
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Integrin beta-32002
Tyrosine-protein kinase Fyn0101
Procathepsin L0112
Aldo-keto reductase family 1 member B10202
ATP-dependent translocase ABCB10305
Integrin alpha-IIb2002
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0415
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0112
Polyunsaturated fatty acid lipoxygenase ALOX150202
Angiotensin-converting enzyme0202
D(2) dopamine receptor0304
Alpha-1B adrenergic receptor0606
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0404
D0303
D(3) dopamine receptor0202
Alpha-2B adrenergic receptor0617
D(2) dopamine receptor0101
Proteasome subunit beta type-10001
Substance-K receptor0404
D(1A) dopamine receptor0304
D(4) dopamine receptor0304
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0617
UDP-glucuronosyltransferase 1A40001
Alpha-2A adrenergic receptor0617
Alpha-1D adrenergic receptor0707
Sodium-dependent noradrenaline transporter 0628
Histamine H2 receptor0202
D(1B) dopamine receptor0202
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A0404
Trypanothione reductase0202
D(4) dopamine receptor0202
Histamine H1 receptor0112
Melanocortin receptor 40202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0202
Mu-type opioid receptor0202
Glutamate receptor ionotropic, NMDA 1 1214
D(3) dopamine receptor0304
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0202
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0404
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0707
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
5-hydroxytryptamine receptor 60404
Gastrin/cholecystokinin type B receptor0101
Spike glycoprotein7119
Proteasome subunit alpha type-60012
Calmodulin 0112
Aldehyde oxidase 10101
Glutamate receptor ionotropic, NMDA 2A 0213
Glutamate receptor ionotropic, NMDA 2C0213
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Sodium-dependent dopamine transporter 0617
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10101
Aldehyde oxidase0202
Potassium voltage-gated channel subfamily H member 20505
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0202
Glutamate receptor ionotropic, NMDA 2C0101
Sodium channel protein type 9 subunit alpha0202
Glutamate receptor ionotropic, NMDA 2D0213
Nuclear receptor subfamily 3 group C member 3 0202
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0213
D0101
Sodium channel protein type 2 subunit alpha0101
Proteasome subunit beta type-70001
Sigma non-opioid intracellular receptor 10404
Angiotensin-converting enzyme 2 0112
Sodium channel protein type 3 subunit alpha0202
Glutamate receptor ionotropic, NMDA 3A0213
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0101
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit delta0303
Amyloid-beta precursor protein0404
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10325
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit gamma-20314
Liver carboxylesterase 10001
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30314
Gamma-aminobutyric acid receptor subunit alpha-50325
Gamma-aminobutyric acid receptor subunit alpha-30314
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20314
Gamma-aminobutyric acid receptor subunit beta-20314
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit epsilon0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60303
Sodium-dependent dopamine transporter0202
Gamma-aminobutyric acid receptor subunit gamma-10303
Gamma-aminobutyric acid receptor subunit gamma-30303
Leukotriene B4 receptor 20101
Gamma-aminobutyric acid receptor subunit theta0303
Transporter0315
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
endonuclease IV1001
dopamine D1 receptor2002
pregnane X receptor4004
aldehyde dehydrogenase 1 family, member A1100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
peripheral myelin protein 22 isoform 11001
atrial natriuretic peptide receptor 1 precursor1001
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10505
activating transcription factor 67007
importin subunit beta-1 isoform 11001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
Rap guanine nucleotide exchange factor 34004
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Thymidine kinase, cytosolic0102
Deoxycytidine kinase0001
AAA family ATPase 0001
Sterol O-acyltransferase 10101
Gamma-aminobutyric acid 0101
Fatty acid-binding protein, liver0303
Alpha-1-acid glycoprotein 10001
Gamma-aminobutyric acid receptor subunit alpha-10203
Gamma-aminobutyric acid receptor subunit beta-10203
Neuronal acetylcholine receptor subunit alpha-42328
Gamma-aminobutyric acid receptor subunit alpha-20203
Gamma-aminobutyric acid receptor subunit alpha-30203
Neuronal acetylcholine receptor subunit beta-22328
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit alpha-40203
Gamma-aminobutyric acid receptor subunit gamma-20203
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
SMAD family member 27007
SMAD family member 37007
thyroid stimulating hormone receptor3003
glucocerebrosidase2002
lysosomal alpha-glucosidase preproprotein3003
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
DNA polymerase iota isoform a (long)5005
replicative DNA helicase0002
recombinase A0022
UDP-glucuronosyltransferase 1A90002
UDP-glucuronosyltransferase 2B170001
UDP-glucuronosyltransferase 2B70001
UDP-glucuronosyltransferase 1-60001
UDP-glucuronosyltransferase 1A1 0102
UDP-glucuronosyltransferase 1A70001
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain5005
hypoxia-inducible factor 1 alpha subunit7007
thyrotropin-releasing hormone receptor3003
Luciferase6006
EWS/FLI fusion protein8008
Glucose-6-phosphate 1-dehydrogenase0101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Sodium/bile acid cotransporter0101
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Chain A, Cruzipain3003
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Neuronal acetylcholine receptor subunit beta-20314
Neuronal acetylcholine receptor subunit alpha-70325
Beta-1 adrenergic receptor 0012
beta-2 adrenergic receptor2002
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0214
Beta-2 adrenergic receptor0011
Beta-adrenergic receptor kinase 10011
Beta-3 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Vasopressin V1a receptor0011
Beta-1 adrenergic receptor0112
Alpha-1A adrenergic receptor0124
Alpha-1B adrenergic receptor0124
Beta-2 adrenergic receptor0101
Taste receptor type 2 member 380011
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310022
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600022
Oxytocin receptor0011
Taste receptor type 2 member 420011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140022
Taste receptor type 2 member 130022
Taste receptor type 2 member 100011
Taste receptor type 2 member 90022
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40022
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Chymotrypsinogen A0101
Potassium channel subfamily K member 30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
galanin receptor type 30101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
nuclear factor NF-kappa-B p105 subunit isoform 11001
Chain E, Fibrin beta chain0101
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, JmjC domain-containing histone demethylation protein 3A4004
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
PPM1D protein2002
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase2002
hypothetical protein, conserved1001
isocitrate dehydrogenase 1, partial2002
luciferase1001
bromodomain adjacent to zinc finger domain 2B4004
serine-protein kinase ATM isoform a2002
neutrophil cytosol factor 10101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
caspase-9 isoform alpha precursor0101
huntingtin isoform 21001
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Vpr3003
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Amine oxidase [flavin-containing] A0101
Cruzipain0101
Alpha-synuclein2204
Guanine nucleotide-binding protein G2002
Inositol monophosphatase 12002
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
nonstructural protein 13003
nuclear receptor subfamily 1, group I, member 23003
Nuclear receptor subfamily 1 group I member 20022
Nuclear receptor subfamily 1 group I member 20011
cytochrome P450 2C9 precursor3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
Prostaglandin G/H synthase 10303
Disintegrin and metalloproteinase domain-containing protein 173104
Aldo-keto reductase family 1 member B10101
Trace amine-associated receptor 10011
5-hydroxytryptamine receptor 3E0101
interleukin 82002
Neuronal acetylcholine receptor subunit alpha-40213
Transient receptor potential cation channel subfamily A member 10011
5-hydroxytryptamine receptor 3B0101
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-30225
Acetylcholine receptor subunit gamma0213
Neuronal acetylcholine receptor subunit alpha-40101
Acetylcholine receptor subunit beta0213
Neuronal acetylcholine receptor subunit alpha-20225
Neuronal acetylcholine receptor subunit beta-30225
Neuronal acetylcholine receptor subunit beta-40225
Neuronal acetylcholine receptor subunit alpha-50225
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50011
Neuronal acetylcholine receptor subunit beta-40213
Neuronal acetylcholine receptor subunit alpha-30213
Neuronal acetylcholine receptor subunit alpha-60225
Neuronal acetylcholine receptor subunit alpha-90225
Neuronal acetylcholine receptor subunit alpha-40213
5-hydroxytryptamine receptor 3A0101
Neuronal acetylcholine receptor subunit alpha-70202
Nuclear receptor ROR-gamma3003
Acetylcholine-binding protein0112
Acetylcholine receptor subunit epsilon0011
Neuronal acetylcholine receptor subunit beta-30112
Acetylcholine receptor subunit delta0213
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130112
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
Solute carrier family 22 member 10101
5-hydroxytryptamine receptor 3D0101
Transient receptor potential cation channel subfamily A member 10011
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
5-hydroxytryptamine receptor 3C0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-100225
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, BCL-2-RELATED PROTEIN A10011
putative potassium channel subunit0011
serine/threonine-protein kinase PLK12002
bcl-2-like protein 11 isoform 10011
Fatty-acid amide hydrolase 10101
Prostaglandin G/H synthase 1 0202
Sterol O-acyltransferase 10101
Trypsin0101
Fatty acid-binding protein, liver0011
Seed linoleate 13S-lipoxygenase-10101
Coagulation factor VII0101
DNA topoisomerase 10101
Aromatase0101
Tissue factor0101
Fatty acid-binding protein, adipocyte0202
Protein kinase C alpha type0001
Tyrosine-protein phosphatase non-receptor type 10101
Sterol O-acyltransferase 10101
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin G/H synthase 20101
Fatty acid-binding protein 50101
Peroxisome proliferator-activated receptor delta0001
Peroxisome proliferator-activated receptor alpha1012
Rap guanine nucleotide exchange factor 41001
Transient receptor potential cation channel subfamily V member 20101
cytochrome P450 2C19 precursor2002
chaperonin GroEL1001
Alpha-1A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
Alpha-2A adrenergic receptor0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Nischarin0101
15-lipoxygenase, partial3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
Solute carrier family 22 member 20101
Solute carrier family 22 member 30101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Indoleamine 2,3-dioxygenase 10101
Fatty acid synthase0202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Multidrug and toxin extrusion protein 20101
Indoleamine 2,3-dioxygenase 20101
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Parkin1001
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 10101
Polyunsaturated fatty acid 5-lipoxygenase0101
Prostaglandin G/H synthase 20202
Prostaglandin G/H synthase 2 0101
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0101
Solute carrier family 22 member 80102
Solute carrier family 22 member 110102
Sodium/potassium/calcium exchanger 40112
Sodium/potassium/calcium exchanger 20112
luciferase0001
Estrogen receptor0415
Progesterone receptor0416
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0416
Androgen receptor0415
Glutamine synthetase0011
Nociceptin receptor0011
Estrogen receptor beta0314
Interstitial collagenase0203
72 kDa type IV collagenase0304
Stromelysin-10303
Matrilysin0202
Matrix metalloproteinase-90101
Neutrophil collagenase0202
Collagenase 30304
Melatonin receptor type 1A0101
Melatonin receptor type 1C0101
Matrix metalloproteinase-140101
Melatonin receptor type 1B0101
heat shock protein HSP 90-alpha isoform 20102
heat shock protein 90, putative0001
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Neuromedin-K receptor0011
Substance-K receptor0112
Substance-P receptor0213
Neuromedin-K receptor0112
Substance-P receptor0101
Substance-K receptor0101
Substance-K receptor0101
Growth hormone secretagogue receptor type 10011
Mas-related G-protein coupled receptor member X20011
polyunsaturated fatty acid lipoxygenase ALOX121001
fMet-Leu-Phe receptor0101
Multidrug resistance-associated protein 50101
fMet-Leu-Phe receptor0101
Lanosterol 14-alpha demethylase0101
Solute carrier family 22 member 120101
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Tetracycline resistance protein, class B0001
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
Multidrug transporter MdfA0101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
Cannabinoid receptor 10101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Integrase 0101
P2Y purinoceptor 120101
Protein-arginine deiminase type-40101
Solute carrier family 22 member 70001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
apical membrane antigen 1, AMA11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]