A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
| Member | Definition | Class |
|---|
| 1-bromopropane | A bromoalkane that is propane carrying a bromo substituent at position 1. | 1-bromopropane |
| 2,2'-thiodiethanol | A diol that is pentane-1,5-diol in which the methylene group at position 3 is replaced by a sulfur atom | thiodiglycol |
| benzotrifluoride | A fluorohydrocarbon that is fluoroform in which the hydrogen is substituted by a phenyl group. | (trifluoromethyl)benzene |
| benzyl alcohol | An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent. | benzyl alcohol |
| bromoethane | A bromoalkane that is ethane carrying a bromo substituent. It is an alkylating agent used as a chemical intermediate in various organic syntheses. | bromoethane |
| chlorobenzene | The simplest member of the class of monochlorobenzenes, that is benzene in which a single hydrogen has been substituted by a chlorine. | chlorobenzene |
| cyclohexanol | An alcohol that consists of cyclohexane bearing a single hydroxy substituent. The parent of the class of cyclohexanols. | cyclohexanol |
| decalin | An ortho-fused bicyclic hydrocarbon that is the decahydro- derivative of naphthalene. | decalin |
| diethylene glycol monomethyl ether | A hydroxypolyether that is the monomethyl ether derivative of diethylene glycol. | 2-(2-methoxyethoxy)ethanol |
| diglyme | A polyether that is the dimethyl ether derivative of diethylene glycol. | diglyme |
| ethylene glycol | A 1,2-glycol compound produced via reaction of ethylene oxide with water. | ethylene glycol |
| formamide | The simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes. | formamide; formimidic acid |
| formic acid | The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects. | formic acid |
| glycerol | A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups. | glycerol |
| isophorone | A cyclic ketone, the structure of which is that of cyclohex-2-en-1-one substituted by methyl groups at positions 3, 5 and 5. | isophorone |
| methyl carbonate | A carbonate ester that is carbonic acid in which both hydrogens are replaced by methyl groups. A flammable, colourless liquid (m.p. 2-4degreeC, b.p. 90degreeC) with a characterstic ester-like odour, it is used as a 'green' methylating agent and as a solvent. | dimethyl carbonate |
| methyl cellosolve | A hydroxyether that is ethanol substituted by a methoxy group at position 2. | 2-methoxyethanol |
| oleic acid | An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry. | oleic acid |
| perfluorodecalin | A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute. | perfluorodecalin |
| perfluorotributylamine | An organofluorine compound that is tributylamine in which all the hydrogens have been replaced by fluorine atoms. | perfluorotributylamine |
| phosphoric acid | A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. | phosphoric acid |
| triacetin | A triglyceride obtained by acetylation of the three hydroxy groups of glycerol. It has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections. | triacetin |
| triglyme | A polyether that consists of dodecane in which the carbon atoms at positions 2, 5, 8 and 11 are replaced by oxygen atoms. | triglyme |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 67.9K protein | Vaccinia virus | Potency | 5.0119 | 1 | 1 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 57.5377 | 3 | 4 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 55.4927 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 28.8752 | 1 | 4 |
| AR protein | Homo sapiens (human) | Potency | 19.7276 | 6 | 9 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 62.6562 | 2 | 6 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 15.4642 | 1 | 2 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 38.0544 | 1 | 5 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 17.9008 | 2 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 89.1251 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 3.1623 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 4.2209 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 17.9008 | 2 | 2 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 79.4328 | 1 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 28.2576 | 1 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 43.9628 | 1 | 4 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 23.7781 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 20.6696 | 8 | 21 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 32.2411 | 3 | 6 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 25.0836 | 5 | 13 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 5.7729 | 2 | 6 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 29.2432 | 3 | 10 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 38.9297 | 3 | 6 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 5.6038 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 49.2971 | 2 | 2 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 108.9313 | 1 | 3 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 32.9838 | 1 | 2 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 42.5486 | 1 | 4 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 0.0398 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 17.9180 | 1 | 2 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 12.5893 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 58.8246 | 2 | 4 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 36.2959 | 4 | 8 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 21.5880 | 1 | 2 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 59.6983 | 1 | 4 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 10.0000 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 30.4793 | 2 | 3 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 16.0996 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 39.3682 | 4 | 5 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 35.4813 | 1 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 24.3312 | 3 | 5 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 234.5639 | 2 | 8 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 562.3410 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 20.2542 | 1 | 4 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 30.6953 | 2 | 8 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 41.3853 | 3 | 20 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 39.5502 | 2 | 10 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 10.6213 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 20.8418 | 1 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 20.8418 | 1 | 2 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 39.8107 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 25.1436 | 2 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 89.1251 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 39.2000 | 3 | 5 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 15.1861 | 1 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 7.7379 | 3 | 10 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 51.5749 | 2 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 14.2102 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 15.6243 | 3 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 5.6038 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 2-dehydropantoate 2-reductase | Escherichia coli K-12 | Ki | 27,000.0000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 32.7000 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| DNA topoisomerase 1 | Homo sapiens (human) | IC50 | 31.0000 | 1 | 1 |
| Fatty acid-binding protein 5 | Homo sapiens (human) | Ki | 0.2480 | 1 | 1 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | IC50 | 26.1000 | 1 | 1 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | Ki | 0.8425 | 2 | 2 |
| Fatty acid-binding protein, liver | Rattus norvegicus (Norway rat) | Ki | 1.5400 | 2 | 2 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | Ki | 6.0000 | 1 | 1 |
| Fe(3+)-Zn(2+) purple acid phosphatase | Phaseolus vulgaris | Ki | 2,000.0000 | 1 | 1 |
| Nociceptin receptor | Mus musculus (house mouse) | Ki | 20,000.0000 | 1 | 1 |
| Ornithine transcarbamylase, mitochondrial | Homo sapiens (human) | Ki | 12,666.6667 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 500.0000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | IC50 | 500.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 40,000.0000 | 2 | 2 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | Ki | 22.0000 | 1 | 1 |
| Sterol O-acyltransferase 1 | Homo sapiens (human) | IC50 | 1,000.0000 | 2 | 2 |
| Sterol O-acyltransferase 1 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 80.0000 | 1 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 2 | 2 |
| Trypsin | Sus scrofa (pig) | IC50 | 200.0000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 6.2000 | 1 | 1 |