Diabetic Coma

A state of unconsciousness as a complication of diabetes mellitus. It occurs in cases of extreme HYPERGLYCEMIA or extreme HYPOGLYCEMIA as a complication of INSULIN therapy.

Synonym
Diabetic Coma

Excerpt	Reference
"The prognosis of diabetic coma is much better than 20 years ago, in particular because of much improved and continuous supervision of the circulation (CVP, ECG, K+ etc."	( Blatter, G; Candinas, R; Froesch, ER; Morell, B; Süsstrunk, H, 1979)
"The diabetic coma is characterized by fundamental metabolic changes."	( Sailer, D, 1984)
"Hyperosmolar diabetic coma is characterised by extreme hyperglycaemia and dehydration."	( Bataille, C, 1980)
"Diabetic coma is an acute complication of DM caused by diabetic ketoacidosis or hyperosmolar hyperglycemic state, which is characterized by extreme hyperglycemia accompanied by coma."	( Choi, JE; Kim, C; Kim, H; Kim, W; Sohn, J, 2018)

Excerpt	Reference
"In the treatment of diabetic coma this regimen of insulin administration has proved simple, safe and effective since 1946."	( Jutzi, E; Menzel, R; Zander, E, 1976)
"Thus treatment of diabetic coma requires appropriate fluid and electrolyte replacement as a life-saving emergency action alongside insulin replacement."	( Bratusch-Marrain, P; Kleinberger, G; Komjati, M; Waldhäusl, W, 1984)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	560 (88.75)	23.3326
1990's	33 (5.23)	12.5806
2000's	21 (3.33)	18.1394
2010's	17 (2.69)	28.8240
2020's	0 (0.00)	9.53

Drug	Relationship Strength	Studies	Trials
2,3-diphosphoglycerate	low	2	0
acetoacetic acid	low	1	0
gamma-aminobutyric acid	low	2	0
acetone	low	22	0
adenine	low	1	0
ammonium hydroxide	low	1	0
carnitine	low	1	0
chlorine	low	21	0
3-hydroxybutyric acid	low	2	0
creatine	low	1	0
cytosine	low	1	0
lactic acid	low	9	0
glycine	low	2	0
glycerol	low	5	0
hydrogen carbonate	low	59	0
iodine	low	4	0
pyruvaldehyde	low	1	0
methanol	low	1	0
inositol	low	1	0
niacin	low	1	0
parathion	low	1	0
pyrazinamide	low	1	0
pyruvic acid	low	3	0
thiamine	low	3	0
toluene	low	1	0
uric acid	low	3	0
urea	low	14	0
vanilmandelic acid	low	1	0
1-anilino-8-naphthalenesulfonate	low	3	0
homovanillic acid	low	1	0
phenytoin	low	2	0
hydroxyindoleacetic acid	low	5	0
acetohexamide	low	2	0
diatrizoic acid	low	1	0
amoxapine	low	1	0
aspirin	low	2	0
azathioprine	low	1	0
bendroflumethiazide	low	1	0
buformin	low	1	0
caffeine	low	1	0
chloroquine	low	1	0
chlorothiazide	low	1	0
chlorpromazine	low	1	0
chlorpropamide	low	12	0
chlorthalidone	low	6	0
clofibrate	low	1	0
clotiazepam	low	1	0
dantrolene	low	1	0
diazoxide	low	3	0
diphenhydramine	low	1	0
ethacrynic acid	low	1	0
ether	low	1	0
berotek	low	1	0
fentanyl	low	1	0
flucytosine	low	1	0
flumazenil	low	1	0
fluorouracil	low	1	0
furosemide	low	8	0
gliclazide	low	1	0
glutethimide	low	1	0
glyburide	low	9	0
guaifenesin	low	1	0
halothane	low	2	0
hydralazine	low	1	0
hydrochlorothiazide	low	4	0
lidocaine	low	1	0
isoniazid	low	1	0
isoproterenol	low	3	0
lorazepam	low	1	0
loxapine	low	1	0
metformin	low	3	0
methylphenidate	low	1	0
metolazone	low	1	0
apnea	low	2	0
octopamine	low	1	0
oxazepam	low	1	0
papaverine	low	1	0
phenobarbital	low	4	0
phenylbutazone	low	1	0
piracetam	low	1	0
potassium chloride	low	11	0
probenecid	low	1	0
propranolol	low	5	0
sibutramine	low	1	0
sulfadiazine	low	1	0
succinylcholine	low	1	0
sulfanilamide	low	1	0
nikethamide	low	1	0
tolbutamide	low	23	0
hydrocortisone acetate	low	1	0
prednisolone	low	6	0
reserpine	low	2	0
phentolamine	low	2	0
sorbitol	low	3	0
alloxan	low	4	0
thyroxine	low	4	0
spironolactone	low	1	0
aldosterone	low	1	0
prednisone	low	10	0
penicillin g	low	1	0
triiodothyronine	low	4	0
biguanides	low	11	0
carbon tetrachloride	low	1	0
ethinyl estradiol	low	1	0
adenosine diphosphate	low	1	0
levodopa	low	1	0
tyrosine	low	3	0
ampicillin	low	1	0
mannitol	medium	9	1
ornithine	low	1	0
valine	low	1	0
tryptophan	low	4	0
ethyl chloride	low	1	0
tromethamine	low	5	0
methylprednisolone	low	2	0
xylitol	low	1	0
phenformin	low	6	0
meglumine	medium	1	1
dydrogesterone	low	1	0
thiamine pyrophosphate	low	9	0
carbutamide	low	5	0
betamethasone	low	1	0
sodium carbonate	low	1	0
metahexamide	low	1	0
ethambutol	low	1	0
streptomycin	low	1	0
carbonates	low	2	0
n-methylaspartate	low	1	0
technetium	low	1	0
chromium	low	2	0
chlorine	low	1	0
ammonium chloride	low	1	0
phenyl acetate	low	2	0
4-methoxyamphetamine	low	3	0
tramadol	low	1	0
tobramycin	low	1	0
diltiazem	low	1	0
propiconazole	low	2	0
captopril	low	2	0
potassium phosphate	low	1	0
glucose, (beta-d)-isomer	low	1	0
1,5-anhydroglucitol	low	2	0
nicotine	low	1	0
fibrinogen	low	4	0
cgp 35348	low	1	0
deoxyglucose	low	2	0
caprylates	low	1	0
cyclic adp-ribose	low	1	0
methotrexate	low	1	0
atropine	low	2	0
cortisone	low	2	0
hydroxydione	low	2	0
glycogen	low	9	0
fibrin	low	2	0
strychnine	low	1	0
acetyl coenzyme a	low	1	0
tacrolimus	low	1	0
sodium bicarbonate	low	4	0
arginine vasopressin	low	1	0
methimazole	low	1	0
D-fructopyranose	low	13	0
lithium	low	1	0
nitrogen dioxide	low	1	0
quinine	low	1	0
17-ketosteroids	low	1	0
icodextrin	low	1	0
amphotericin b	low	3	0
humulene	low	3	0
acitretin	low	1	0
naloxone	low	2	0
deamino arginine vasopressin	low	1	0
cysteine	low	1	0
phosphorus	low	4	0
nitrofurantoin	low	1	0
phosphocreatine	low	1	0
dapagliflozin	low	1	0
losartan potassium	low	1	0
indocyanine green	low	1	0
pituitrin	low	8	0
acid phosphatase	low	2	0
nad	low	2	0
cosyntropin	low	1	0
glucagon	medium	34	2
insulin detemir	low	1	0
c-peptide	low	6	0
sodium salicylate	low	1	0
insulin, isophane	low	2	0
heme	medium	1	1
tetracycline	low	1	0
salicylates	low	1	0
warfarin	low	2	0
insulin glargine	low	2	0
cyclosporine	low	1	0
guanine	low	1	0
rifampin	low	1	0
olanzapine	low	1	0
allopurinol	low	1	0
reamberin	medium	1	1

Protein Targets (1,405)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	4	0	0	4
thioredoxin reductase	38	0	0	38
USP1 protein, partial	22	0	0	22
TDP1 protein	55	0	0	55
vitamin D3 receptor isoform VDRA	18	0	0	18
importin subunit beta-1 isoform 1	7	0	0	7
flap endonuclease 1	18	0	0	18
serine/threonine-protein kinase PLK1	5	0	0	5
snurportin-1	7	0	0	7
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
DNA polymerase eta isoform 1	8	0	0	8
DNA polymerase iota isoform a (long)	17	0	0	17
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
geminin	55	0	0	55
DNA polymerase kappa isoform 1	15	0	0	15
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	2	0	2
Transthyretin	0	1	1	4
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	1	2	3
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	8	0	0	8
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Protein skinhead-1	0	1	0	1
Monocarboxylate transporter 2	0	3	0	3
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
5-hydroxytryptamine receptor 2C	0	7	1	9
5-hydroxytryptamine receptor 2A	0	6	1	7
5-hydroxytryptamine receptor 1A	0	9	2	12
5-hydroxytryptamine receptor 1B	0	5	1	6
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	5	1	6
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	16	1	17
Sodium-dependent serotonin transporter	0	3	0	3
5-hydroxytryptamine receptor 7	0	2	1	3
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
Monocarboxylate transporter 4	0	0	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	15	0	0	15
Chain A, Beta-lactamase	13	0	0	13
phosphopantetheinyl transferase	25	0	0	25
RAR-related orphan receptor gamma	37	0	0	37
GLS protein	33	0	0	33
aldehyde dehydrogenase 1 family, member A1	40	0	0	40
thyroid stimulating hormone receptor	34	0	0	34
farnesoid X nuclear receptor	23	0	0	23
estrogen nuclear receptor alpha	68	0	0	68
G	18	0	0	18
glucocerebrosidase	6	0	0	6
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	55	0	0	55
aryl hydrocarbon receptor	19	0	0	19
Bloom syndrome protein isoform 1	19	0	0	19
thyroid hormone receptor beta isoform a	22	0	0	22
nuclear factor erythroid 2-related factor 2 isoform 1	46	0	0	46
histone acetyltransferase KAT2A isoform 1	16	0	0	16
muscarinic acetylcholine receptor M1	21	0	0	21
lamin isoform A-delta10	54	0	0	54
Interferon beta	23	0	0	23
HLA class I histocompatibility antigen, B alpha chain	18	0	0	18
Inositol hexakisphosphate kinase 1	18	0	0	18
cytochrome P450 2C9, partial	18	0	0	18
glucocorticoid receptor [Homo sapiens]	51	0	0	51
estrogen-related nuclear receptor alpha	47	0	0	47
thyroid hormone receptor beta isoform 2	36	0	0	36
N-alpha-acetyltransferase 50	0	0	1	1
Luciferase	16	0	0	16
Microtubule-associated protein tau	21	0	0	21
AR protein	57	0	0	57
peroxisome proliferator activated receptor gamma	27	0	0	27
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	24	0	0	24
eyes absent homolog 2 isoform a	1	0	0	1
peripheral myelin protein 22	26	0	0	26
survival motor neuron protein isoform d	18	0	0	18
ATP-binding cassette sub-family C member 3	0	56	0	56
Multidrug resistance-associated protein 4	0	56	0	57
Bile salt export pump	0	20	0	20
Bile salt export pump	0	72	0	72
Rap guanine nucleotide exchange factor 3	5	0	0	5
Cellular tumor antigen p53	33	0	0	33
Rap guanine nucleotide exchange factor 4	1	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	25	0	0	25
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear receptor subfamily 1, group I, member 3	35	0	0	35
cytochrome P450 family 3 subfamily A polypeptide 4	32	0	0	32
pregnane X nuclear receptor	39	0	0	39
nuclear factor erythroid 2-related factor 2 isoform 2	13	0	0	13
heat shock protein beta-1	9	0	0	9
tumor susceptibility gene 101 protein	1	0	0	1
Voltage-dependent calcium channel gamma-2 subunit	21	0	0	21
Cyclin-dependent kinase 1	0	1	0	1
Heat shock protein HSP 90-beta	0	2	1	4
Glutamate receptor 2	21	1	0	24
Xanthine dehydrogenase/oxidase	0	4	0	4
TAR DNA-binding protein 43	16	0	0	16
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	0	2
ATPase family AAA domain-containing protein 5	11	0	0	11
Ataxin-2	19	0	0	19
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
regulator of G-protein signaling 4	21	0	0	21
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	12	5	18
Delta-type opioid receptor	0	8	3	12
Kappa-type opioid receptor	0	10	4	15
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	9	0	0	9
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	4	0	4
Mineralocorticoid receptor	0	5	3	9
Androgen receptor	0	10	0	11
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	3	0	4
interleukin 8	10	0	0	10
estrogen receptor 2 (ER beta)	19	0	0	19
progesterone receptor	26	0	0	26
IDH1	16	0	0	16
transcriptional regulator ERG isoform 3	8	0	0	8
ras-related protein Rab-9A	5	0	0	5
Polyphenol oxidase 2	0	5	0	8
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	2
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	5	3	9
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	2	1	4
Purine nucleoside phosphorylase	0	0	1	1
Canalicular multispecific organic anion transporter 1	0	55	0	55
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	1	0	3
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
Chain A, 2-oxoglutarate Oxygenase	18	0	0	18
Chain A, ATP-DEPENDENT DNA HELICASE Q1	4	0	0	4
Chain A, Xcogt	0	0	1	1
Chain A, Xcogt	0	0	1	1
Chain A, Xcogt	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Disintegrin and metalloproteinase domain-containing protein 17	5	0	0	5
Chain A, Ferritin light chain	11	0	0	11
endonuclease IV	8	0	0	8
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
Fumarate hydratase	9	0	0	9
NFKB1 protein, partial	8	0	0	8
GLI family zinc finger 3	43	0	0	43
Thrombopoietin	8	0	0	8
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
isocitrate dehydrogenase 1, partial	2	0	0	2
EWS/FLI fusion protein	24	0	0	24
retinoic acid nuclear receptor alpha variant 1	37	0	0	37
cytochrome P450 2D6	17	0	0	17
polyprotein	9	0	0	9
67.9K protein	10	0	0	10
activating transcription factor 6	13	0	0	13
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
v-jun sarcoma virus 17 oncogene homolog (avian)	20	0	0	20
cytochrome P450 2D6 isoform 1	11	0	0	11
peripheral myelin protein 22 isoform 1	13	0	0	13
cellular tumor antigen p53 isoform a	7	0	0	7
D(1A) dopamine receptor	12	0	0	12
atrial natriuretic peptide receptor 1 precursor	8	0	0	8
chromobox protein homolog 1	38	0	0	38
potassium voltage-gated channel subfamily H member 2 isoform d	19	0	0	19
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
cytochrome P450 3A4 isoform 1	21	0	0	21
M-phase phosphoprotein 8	15	0	0	15
transient receptor potential cation channel subfamily V member 1	2	0	0	2
neuropeptide S receptor isoform A	10	0	0	10
Gamma-aminobutyric acid receptor subunit pi	21	6	2	29
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
5-hydroxytryptamine receptor 4	0	14	1	15
Aldo-keto reductase family 1 member B1	0	12	0	12
Muscarinic acetylcholine receptor M2	0	12	2	17
Muscarinic acetylcholine receptor M4	0	11	1	14
5-hydroxytryptamine receptor 1A	0	4	1	5
Muscarinic acetylcholine receptor M5	0	11	1	14
Alpha-2A adrenergic receptor	0	10	3	15
Cytochrome P450 2D6	0	9	1	10
Muscarinic acetylcholine receptor M1	0	12	3	18
D(2) dopamine receptor	0	11	1	13
Gamma-aminobutyric acid receptor subunit beta-1	21	6	2	29
Alpha-2B adrenergic receptor	0	11	2	15
Gamma-aminobutyric acid receptor subunit delta	21	6	2	29
Gamma-aminobutyric acid receptor subunit gamma-2	21	6	3	30
Alpha-2C adrenergic receptor	0	10	3	15
Gamma-aminobutyric acid receptor subunit alpha-5	21	6	2	29
Gamma-aminobutyric acid receptor subunit alpha-3	21	6	2	29
Muscarinic acetylcholine receptor M3	0	12	2	16
D(1A) dopamine receptor	0	8	1	10
D(4) dopamine receptor	0	9	0	10
Gamma-aminobutyric acid receptor subunit gamma-1	21	6	2	29
Gamma-aminobutyric acid receptor subunit alpha-2	21	6	2	29
Sodium-dependent noradrenaline transporter	0	15	0	15
Alpha-1D adrenergic receptor	0	10	3	14
5-hydroxytryptamine receptor 2A	0	14	1	15
5-hydroxytryptamine receptor 2C	0	14	1	15
Gamma-aminobutyric acid receptor subunit alpha-4	21	6	2	29
Gamma-aminobutyric acid receptor subunit gamma-3	21	6	2	29
Gamma-aminobutyric acid receptor subunit alpha-6	21	6	2	29
5-hydroxytryptamine receptor 7	0	4	1	5
Histamine H1 receptor	0	10	1	11
D(3) dopamine receptor	0	9	0	10
5-hydroxytryptamine receptor 2B	0	12	1	13
Histamine H2 receptor	12	0	1	15
D(1A) dopamine receptor	3	0	0	3
Sulfotransferase 1A1	0	3	1	5
5-hydroxytryptamine receptor 6	0	9	1	10
Gamma-aminobutyric acid receptor subunit alpha-1	21	7	3	31
Gamma-aminobutyric acid receptor subunit beta-3	21	6	2	29
Gamma-aminobutyric acid receptor subunit beta-2	21	6	3	30
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Sulfotransferase 2A1	0	1	0	1
GABA theta subunit	21	6	2	29
Gamma-aminobutyric acid receptor subunit epsilon	21	6	2	29
Histamine H4 receptor	0	3	1	4
ATP-dependent phosphofructokinase	24	0	0	24
Chain A, HADH2 protein	14	0	0	14
Chain B, HADH2 protein	14	0	0	14
Chain A, Cruzipain	5	0	0	5
peroxisome proliferator-activated receptor delta	23	0	0	23
vitamin D (1,25- dihydroxyvitamin D3) receptor	21	0	0	21
tumor necrosis factor	1	0	0	1
Cytochrome P450 1A2	0	4	1	5
Cytochrome P450 3A4	0	11	0	12
Cytochrome P450 2C9	0	16	1	17
Cytochrome P450 2C19	0	5	0	5
Nuclear receptor ROR-gamma	11	0	0	11
Potassium voltage-gated channel subfamily H member 2	0	20	0	20
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	8	0	9
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	0	0	2
apical membrane antigen 1, AMA1	5	0	0	5
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	1	1	4
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
DNA polymerase beta	5	0	0	5
Carbonic anhydrase 1	0	20	0	27
Carbonic anhydrase 2	0	22	2	31
60 kDa heat shock protein, mitochondrial	0	3	0	3
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	4	0	4
Solute carrier family 15 member 1	0	3	0	3
Spike glycoprotein	15	2	2	19
10 kDa heat shock protein, mitochondrial	0	3	0	3
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	3	0	3
Metallo-beta-lactamase VIM-13	0	0	0	2
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	4	0	4
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
10 kDa chaperonin	0	4	0	4
Metallo-b-lactamase	0	0	0	2
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	2
Beta-lactamase class B VIM-2	0	1	1	4
Beta-lactamase VIM-1	0	0	0	2
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
ATAD5 protein, partial	20	0	0	20
arylsulfatase A	19	0	0	19
Translocator protein	0	1	1	2
Vasopressin V2 receptor	0	3	2	6
Oxytocin receptor	0	1	2	3
Vasopressin V1a receptor	0	0	3	3
Vasopressin V1a receptor	0	3	3	6
Vasopressin V1b receptor	0	2	2	4
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	2	0	3
Oxytocin receptor	0	1	1	2
Vasopressin V2 receptor	0	2	2	4
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	2	0	0	2
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
lethal factor (plasmid)	11	0	0	11
Prostaglandin-H2 D-isomerase	0	1	0	1
Solute carrier family 22 member 6	0	8	0	8
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	4	0	4
Fatty acid-binding protein, liver	0	4	1	5
Integrin beta-3	4	1	0	5
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Integrin alpha-IIb	4	1	0	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Adenosine receptor A1	0	4	0	7
Adenosine receptor A2a	0	3	1	8
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	5	0	5
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	9	1	10
Sigma non-opioid intracellular receptor 1	0	2	1	3
retinoid X nuclear receptor alpha	30	0	0	30
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	11	0	13
Muscarinic acetylcholine receptor M1	0	5	2	9
Muscarinic acetylcholine receptor M3	0	5	2	9
Muscarinic acetylcholine receptor M4	0	6	2	10
Muscarinic acetylcholine receptor M5	0	5	2	9
Muscarinic acetylcholine receptor M2	0	5	2	10
Muscarinic acetylcholine receptor M1	0	0	0	1
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 7	0	5	0	5
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
acetylcholinesterase	14	0	0	14
SMAD family member 2	10	0	0	10
SMAD family member 3	10	0	0	10
thioredoxin glutathione reductase	8	0	0	8
P53	1	0	0	1
thyroid stimulating hormone receptor	11	0	0	11
Histone H2A.x	10	0	0	10
hemoglobin subunit beta	3	0	0	3
muscleblind-like protein 1 isoform 1	11	0	0	11
Protein-arginine deiminase type-4	0	5	0	5
glp-1 receptor, partial	13	0	0	13
beta-2 adrenergic receptor	2	0	0	2
Beta-2 adrenergic receptor	0	5	4	10
Beta-2 adrenergic receptor	0	3	4	8
pregnane X receptor	10	0	0	10
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	14	3	22
Glycine receptor subunit alpha-1	0	15	0	15
Glycine receptor subunit beta	0	14	0	14
Glycine receptor subunit alpha-2	0	14	0	14
Glycine receptor subunit alpha-3	0	14	0	14
ORF73	0	0	2	2
Solute carrier family 22 member 1	0	7	0	11
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
nuclear receptor ROR-gamma isoform 1	14	0	0	14
Potassium channel subfamily K member 2	0	4	4	8
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	2	0	2
Cholinesterase	0	2	1	3
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	4	2	6
Adenosine receptor A3	0	4	1	5
Replicase polyprotein 1ab	0	3	2	5
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	4	0	4
Amine oxidase [flavin-containing] B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Adenosine receptor A1	0	4	1	7
Vasopressin V2 receptor	0	0	0	1
Serine/threonine-protein kinase mTOR	0	3	0	3
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	2	0	3
Chain A, Beta-lactoglobulin	0	0	1	1
Chain A, Beta-lactoglobulin	0	0	1	1
UDP-3-O-acyl-N-acetylglucosamine deacetylase	0	0	1	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
15-lipoxygenase, partial	6	0	0	6
Prothrombin	0	1	1	2
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	2	1	3
Angiotensin-converting enzyme	0	9	0	10
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Beta-lactamase TEM	0	2	0	3
Mu-type opioid receptor	0	7	2	9
Beta-lactamase	0	2	0	3
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	3	2	5
Cytochrome P450 2E1	0	1	0	1
Carbonic anhydrase 4	0	11	0	17
Carbonic anhydrase	0	6	0	9
Carbonic anhydrase 15	0	4	0	7
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
PPM1D protein	6	0	0	6
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	2	2	4
Replicase polyprotein 1ab	0	2	2	4
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	2	2	4
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	2	2
Amyloid-beta precursor protein	1	3	0	4
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	2	2	4
Replicase polyprotein 1a	0	3	2	5
Replicase polyprotein 1ab	0	3	2	5
Spike glycoprotein	0	1	0	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
DNA ligase 1	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Beta-secretase 1	0	1	0	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
nonstructural protein 1	9	0	0	9
Proteasome subunit beta type-11	0	0	0	1
Smad3	7	0	0	7
caspase 7, apoptosis-related cysteine protease	5	0	0	5
NADPH oxidase 1	0	1	0	1
Snq2p	0	0	0	1
caspase-3	5	0	0	5
Adenylate cyclase type 1	0	2	0	2
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
histone deacetylase 9 isoform 3	3	0	0	3
mitogen-activated protein kinase 1	8	0	0	8
Proteasome subunit alpha type-7	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Albumin	0	5	7	12
Albumin	0	0	3	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Major prion protein	0	0	1	1
Tyrosine-protein kinase Fyn	0	2	0	2
ATP-dependent translocase ABCB1	0	10	0	13
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	7	0	7
Alpha-1B adrenergic receptor	0	12	3	15
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	3	0	3
D(3) dopamine receptor	0	5	0	5
Alpha-2B adrenergic receptor	0	7	3	10
D(2) dopamine receptor	0	1	0	1
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	2	0	2
D(1B) dopamine receptor	0	1	0	2
Adenylate cyclase type 3	0	2	0	2
Alpha-2C adrenergic receptor	0	7	3	10
UDP-glucuronosyltransferase 1A4	0	1	0	5
Alpha-2A adrenergic receptor	0	7	3	10
Alpha-1D adrenergic receptor	0	10	3	14
Sodium-dependent dopamine transporter	0	4	0	4
Histamine H2 receptor	0	2	0	2
D(1B) dopamine receptor	0	2	0	2
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	3	0	3
Histamine H1 receptor	0	2	1	4
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 5	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Glutamate receptor ionotropic, NMDA 1	0	5	3	12
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	4	0	5
Adenylate cyclase type 8	0	2	0	2
Proteasome subunit beta type-10	0	0	0	1
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	12	3	15
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
Cytochrome P450 2J2	0	8	0	8
Gastrin/cholecystokinin type B receptor	0	1	0	1
Proteasome subunit alpha type-6	0	0	1	2
D(2) dopamine receptor	0	4	0	5
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	5	3	12
Glutamate receptor ionotropic, NMDA 2B	0	5	3	12
Glutamate receptor ionotropic, NMDA 2C	0	5	3	12
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Sodium-dependent dopamine transporter	0	9	0	9
Adenylate cyclase type 6	0	2	0	2
Adenylate cyclase type 5	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Aldehyde oxidase	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Sodium channel protein type 5 subunit alpha	0	6	0	6
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	4	0	4
Glutamate receptor ionotropic, NMDA 2D	0	5	3	12
Nuclear receptor subfamily 3 group C member 3	0	7	0	7
Adenylyl cyclase 7	0	2	0	2
Proteasome subunit alpha-type 8	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	5	3	12
D	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	4	0	4
Proteasome subunit beta type-7	0	0	0	1
Sodium channel protein type 3 subunit alpha	0	5	0	5
Glutamate receptor ionotropic, NMDA 3A	0	5	3	12
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	2	0	2
cytochrome P450 2C19 precursor	5	0	0	5
Lanosterol 14-alpha demethylase	0	4	0	4
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	2
Carbonic anhydrase 12	0	7	0	13
Carbonic anhydrase 3	0	5	0	8
Carbonic anhydrase 6	0	8	0	14
Carbonic anhydrase 5A, mitochondrial	0	9	0	16
Carbonic anhydrase 7	0	5	0	11
Carbonic anhydrase 9	0	10	0	16
Carbonic anhydrase 13	0	5	0	10
Carbonic anhydrase 14	0	5	0	11
Carbonic anhydrase 5B, mitochondrial	0	7	0	14
GALC protein	1	0	0	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	5	6
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
dopamine D1 receptor	6	0	0	6
Potassium voltage-gated channel subfamily A member 1	0	1	1	2
Multidrug and toxin extrusion protein 1	0	7	0	7
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	3	0	3
Deoxycytidine kinase	0	0	0	1
Sodium/glucose cotransporter 1	0	1	1	2
Sodium/glucose cotransporter 2	0	1	1	2
Sodium/glucose cotransporter 2	0	0	1	1
Sodium/myo-inositol cotransporter 2	0	2	0	2
Solute carrier family 5 member 4	0	1	0	1
Coagulation factor VII	0	1	0	1
Tissue factor	0	1	0	1
Glutamate receptor 1	0	1	0	3
Glutamate receptor 3	0	1	0	3
Glutamate receptor 4	0	1	0	3
Nicotinamide phosphoribosyltransferase	0	0	1	1
ATP-binding cassette sub-family C member 8	0	2	1	3
ATP-sensitive inward rectifier potassium channel 11	0	2	1	3
huntingtin isoform 2	4	0	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	1	0	1
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Solute carrier family 22 member 2	0	6	0	6
Chain A, GLUTATHIONE TRANSFERASE A1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain A, Glutathione S-transferase P1-1	0	1	0	1
Chain B, Glutathione S-transferase P1-1	0	1	0	1
Nrf2	1	0	0	1
WRN	2	0	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
serine-protein kinase ATM isoform a	1	0	0	1
cytochrome P450 2C9 precursor	7	0	0	7
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	7	0	0	7
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Glutathione S-transferase A1	0	1	0	1
Glutathione S-transferase P	0	1	0	1
60 kDa chaperonin	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 6	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
UDP-glucose 4-epimerase	0	1	0	1
14 kDa phosphohistidine phosphatase	0	2	0	2
large T antigen	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Pantothenate synthetase	0	2	0	2
lysosomal alpha-glucosidase preproprotein	4	0	0	4
Vpr	4	0	0	4
Solute carrier family 22 member 2	0	4	0	5
Cytochrome P450 2B1	0	1	0	1
Estrogen receptor	0	8	2	10
Neuronal acetylcholine receptor subunit alpha-4	2	3	2	8
Neuronal acetylcholine receptor subunit beta-2	2	3	2	8
Cytochrome P450 2B6	0	1	1	2
UDP-glucuronosyltransferase 1A1	0	4	0	5
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Estrogen receptor beta	0	4	2	6
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Delta-type opioid receptor	0	7	1	9
Delta-type opioid receptor	0	8	2	10
Mu-type opioid receptor	0	10	3	13
Kappa-type opioid receptor	0	3	2	5
Kappa-type opioid receptor	0	4	1	6
Mu-type opioid receptor	0	2	0	3
Sigma non-opioid intracellular receptor 1	0	4	1	5
Skn7p	0	0	0	2
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	2	6
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	2	6
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-7	0	3	2	6
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	4
Thymidylate synthase	0	3	0	3
Aromatase	0	1	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	6	0	6
Gamma-aminobutyric acid	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	2
Hsf1 protein	0	0	4	5
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit delta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	1	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Histone deacetylase 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	1	2
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Histone deacetylase 1	0	1	0	1
Sterol O-acyltransferase 1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Gamma-aminobutyric acid receptor subunit pi	0	1	1	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	1	2
Histone deacetylase 6	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	0	1	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Asialoglycoprotein receptor 1	0	1	1	2
Parkin	3	0	0	3
ATP-binding cassette sub-family C member 9	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	3
Chymotrypsinogen A	0	1	0	1
ATP synthase subunit beta, mitochondrial	0	1	0	1
ATP synthase subunit delta, mitochondrial	0	1	0	1
ATP synthase subunit gamma, mitochondrial	0	1	0	1
ATP synthase subunit epsilon, mitochondrial	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Solute carrier family 22 member 7	0	2	0	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	4	0	7
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Glycine receptor subunit alpha-1	0	2	1	3
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	5	0	5
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	2	2
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Purine nucleoside phosphorylase	0	2	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
ClpP	3	0	0	3
Solute carrier family 22 member 8	0	3	0	5
pyruvate kinase	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
N-glycosylase/DNA lyase	0	2	0	2
Ornithine decarboxylase	1	0	0	1
Aspartate aminotransferase, cytoplasmic	0	1	0	1
Lactoperoxidase	0	1	0	1
Single-stranded DNA cytosine deaminase	1	0	0	1
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
alpha-galactosidase	3	0	0	3
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	3	1	4
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
NPYLR7B	0	0	1	1
Beta-1 adrenergic receptor	0	1	2	5
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
Beta-1 adrenergic receptor	0	4	2	6
Beta-2 adrenergic receptor	0	4	1	6
Beta-3 adrenergic receptor	0	3	2	5
Beta-1 adrenergic receptor	0	4	2	8
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Beta-1 adrenergic receptor	0	2	1	3
Alpha-1A adrenergic receptor	0	4	4	9
Alpha-1B adrenergic receptor	0	3	3	7
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	2	2
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	2	2
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	2	2
Beta-2 adrenergic receptor	0	1	1	2
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	2	3
Taste receptor type 2 member 13	0	0	2	2
Taste receptor type 2 member 10	0	0	2	3
Taste receptor type 2 member 9	0	0	2	2
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	2	2
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
Plasma kallikrein	0	0	0	3
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosinase	0	1	0	1
Carbonic anhydrase	0	1	0	4
SLC16A10 protein	0	0	0	3
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase-like protein, putative	0	0	0	3
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Carbonic anhydrase	0	1	0	4
Monocarboxylate transporter 10	0	0	0	3
phosphoglycerate kinase	1	0	0	1
Potassium channel subfamily K member 3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Translocator protein	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Histamine H1 receptor	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Cannabinoid receptor 1	0	2	0	2
Dihydrofolate reductase	0	6	0	7
Dipeptidyl peptidase 4	0	1	0	1
Dopamine beta-hydroxylase	0	2	0	2
Lactoperoxidase	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	3	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
caspase-1 isoform alpha precursor	2	0	0	2
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Caspase-7	3	0	0	3
Solute carrier organic anion transporter family member 1A3	0	0	0	3
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	2	0	4
Canalicular multispecific organic anion transporter 1	0	2	0	3
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	5	0	7
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier organic anion transporter family member 1B3	0	2	0	5
Solute carrier family 22 member 11	0	2	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	0	1
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Kappa-type opioid receptor	0	1	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
5-hydroxytryptamine receptor 3E	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	2	2
5-hydroxytryptamine receptor 3B	0	2	0	2
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Transporter	0	2	1	4
streptokinase A precursor	0	0	2	2
Estrogen receptor	0	0	1	1
Estrogen receptor beta	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Trace amine-associated receptor 1	0	0	1	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Transporter	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Chain A, ARGINASE 1	0	1	0	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE	0	1	0	1
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Vascular endothelial growth factor receptor 1	0	1	0	1
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
CREB-binding protein	1	0	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Cytochrome P450 2D26	0	2	0	2
Cytochrome P450 2D3	0	2	0	2
Cytochrome P450 2D4	0	2	0	2
estrogen receptor beta isoform 1	0	2	0	2
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Nischarin	0	1	0	1
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
Sodium/potassium/calcium exchanger 4	0	1	1	2
Sodium/potassium/calcium exchanger 2	0	1	1	2
luciferase	0	0	0	1
Progesterone receptor	0	4	1	6
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Androgen receptor	0	5	1	6
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	4	0	6
UDP-glucuronosyltransferase 1A9	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	2	0	2
Pannexin-1	0	1	0	1
Solute carrier family 22 member 12	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	2	0	2
UDP-glucuronosyltransferase 1A7	0	1	0	1
UDP-glucuronosyltransferase 1A10	0	1	0	1
Pannexin-1	0	1	0	1
Solute carrier family 22 member 7	0	2	0	3
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
Endothelin-1 receptor	0	1	1	2
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Prolyl 4-hydroxylase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Alpha-synuclein	0	2	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	3
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Glycine receptor subunit beta	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
Aurora kinase A	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Protein argonaute-2	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
Cytochrome P450 3A5	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	2	0	2
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Acetylcholinesterase	0	1	0	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Protein Rev	0	0	1	1
UDP-glucuronosyltransferase 2B10	0	1	0	1
Endolysin	0	0	1	1
Thyroid hormone receptor beta	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	2
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (631)

Protein Targets (1,405)

Diabetic Coma

Synonyms(1)

Research Excerpts

Overview

Treatment

Research

Studies (631)

Drugs Studied (232)

Protein Targets (1,405)