A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.
| Excerpt | Reference |
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| "Leiomyomas are common, estrogen-sensitive, benign neoplasms that decrease in size by 40% to 50% during gonadotropin-releasing hormone agonist treatment." | ( Barbieri, RL; Friedman, AJ; Lobel, SM; Rein, MS, 1990) |
| "Human uterine leiomyoma is a benign tumor and its development is closely related to estrogen." | ( Honjo, H; Kitawaki, J; Naitoh, K; Okada, H; Urabe, M; Yamamoto, T, 1990) |
| "Angioleiomyomas are rare smooth-muscle tumors that occur anywhere in the body." | ( Freedman, AM; Meland, NB, 1989) |
| "Uterine leiomyomas are found in approximately 2% of pregnant women." | ( Dotters, DJ; Droegemeuller, W; Katz, VL, 1989) |
| "Angioleiomyomas are rare tumours that are usually found in the subcutaneous tissue." | ( Duchateau, J; Guelinckx, PJ; Zielonka, E, 1987) |
| "Angioleiomyoma is frequently painful and the cause of the pain is unknown." | ( Geddy, PM; Gray, S; Reid, WA, 1993) |
| "Uterine leiomyoma is the most common female benign pelvic tumor, affecting 20-25% of women during their reproductive years." | ( Marinaccio, M; Paradiso, A; Pinto, V; Reshkin, S, 1994) |
| "Uterine leiomyomas are monoclonal tumors." | ( Barbieri, RL; Friedman, AJ; Rein, MS, 1995) |
| "Uterine leiomyomas are the most common benign neoplasms of the uterus." | ( Austin, DJ; Jain, P; Nowak, RA; Penglase, MD; Stewart, EA, 1996) |
| "Uterine leiomyomas are a major health problem for women of reproductive age." | ( Blin, C; Kahn, A; Leroy, G; Molina, T; Perret, C; Porteux, A; Romagnolo, B; Thomasset, M; Vandewalle, A, 1996) |
| "Uterine leiomyoma is an estrogen-responsive tumor, and the present studies examine the ability of the antiestrogen tamoxifen to modulate leiomyoma cell growth." | ( Ethier, SP; Howe, SR; Matthews, WJ; Pass, HI; Walker, C, 1996) |
| "Uterine leiomyoma is the most frequent gynecologic neoplasm in women." | ( Fuchs-Young, R; Hale, L; Howe, S; Miles, R; Walker, C, 1996) |
| "Uterine leiomyoma is the most common benign smooth muscle cell tumor of the myometrium." | ( Maruo, T; Matsuo, H; Samoto, T, 1997) |
| "Leiomyoma is a benign tumor derived from smooth muscle." | ( Kanzaki, T; Maeda, S; Ohtake, N; Shimoinaba, K, 1997) |
| "Leiomyomas are tumours of uterine smooth muscle tissue that are oestrogen and progesterone dependent." | ( Fujii, S; Horiuchi, A; Iinuma, M; Kobayashi, Y; Nikaido, T; Zhai, YL, 1997) |
| "Because leiomyomas are characterized also by increased cell proliferation and tissue fibrosis, we examined the effects of pirfenidone on cell proliferation and collagen expression in cultured myometrial and leiomyoma smooth muscle cells." | ( Lee, BS; Margolin, SB; Nowak, RA, 1998) |
| "Uterine leiomyoma is the most common smooth muscle cell tumor of the myometrium." | ( Maruo, T; Matsuo, H; Samoto, T; Shimomura, Y, 1998) |
| "Uterine leiomyomas are the most prevalent benign tumor type in women of reproductive age and are one of the most common indications for hysterectomy." | ( Bicknell, R; Hague, S; MacKenzie, IZ; Manek, S; Oehler, MK; Rees, MC; Zhang, L, 2000) |
| "Uterine leiomyoma is a very common benign tumour with unclear pathophysiology in adult women." | ( Adolfsson, PI; Berg, G; Haug, I; Svensson, SP, 2000) |
| "Uterine leiomyomas are monoclonal tumors." | ( Rein, MS, 2000) |
| "Uterine leiomyomas are responsive to the ovarian steroids, estrogen and progesterone; however, a mechanistic understanding of the role of these hormones in the development of this common gynecologic lesion remains to be elucidated." | ( Burroughs, KD; Davis, B; Fuchs-Young, R; Walker, CL, 2000) |
| "Uterine leiomyomas are the most common tumors of the reproductive tract, afflicting women between the ages of 30--55 yr." | ( Sampath, D; Winneker, RC; Zhang, Z; Zhu, Y, 2001) |
| "Leiomyomas are a significant problem in women's health." | ( Nowak, RA, 2001) |
| "However, uterine leiomyomas are a leading cause of morbidity, infertility, and hysterectomy in women." | ( Li, S; McLachlan, JA, 2001) |
| "Pilar leiomyomas are usually multiple and are commonly found on the extensor aspects of the arm, trunk, and face." | ( Kaur, I; Kumar, B; Radotra, BD; Sahoo, B, 2001) |
| "Uterine leiomyoma is a mesenchymal tumor composed of smooth muscle cells with fibrous tissues and many mast cells." | ( Fujii, S; Fukuhara, K; Kanamori, T; Kariya, M; Kusakari, T; Momma, C; Nikaido, T; Orii, A; Shime, H; Takakura, K; Tsuruta, Y, 2002) |
| "Uterine leiomyomas are prevalent estrogen-responsive clonal tumors, but the specific genetic alterations that contribute to their development have not been elucidated." | ( Catherino, WH; Leppert, PC; Nieman, LK; Payson, M; Potlog-Nahari, C; Segars, JH; Stenmark, MH, 2004) |
| "Uterine leiomyomas are the most common gynecological tumors and are a significant health concern for many women." | ( Cook, JD; Walker, CL, 2004) |
| "Uterine leiomyomas are a common disorder resulting in significant morbidity for women and substantial economic impact on the health care system." | ( Al-Hendy, A; Copland, JA; Young, SL, 2004) |
| "Uterine leiomyomas are the most common benign smooth muscle cell tumours in women." | ( Ben-Bassat, H; Hartzstark, Z; Klein, BY; Laufer, N; Levitzki, R; Rojansky, N; Shlomai, Z; Shushan, A, 2004) |
| "Uterine leiomyoma is the most common benign smooth muscle cell tumor of the myometrium." | ( Kim, CH; Kim, DI; Kim, H; Lee, TK; Lee, YC; Lim, IS, 2005) |
| "Lipoleiomyomas are rare, mixed mesenchymal tumors composed of adipose and smooth muscle cells." | ( Cunha, TM; Félix, A; Vasconcelos, C, 2007) |
| "Uterine fibroids or leiomyoma are a common benign smooth muscle tumor." | ( Bryant, HU; Geiser, AG; Helvering, LM; Kulkarini, NH; N'Cho, M; Onyia, JE; Qian, HR; Shou, J; Su, C; Wei, T, 2007) |
| "Human uterine leiomyomas are very common smooth muscle cell tumors that occur in reproductive-age women and are the leading reason for performing hysterectomies." | ( Al-Hendy, A; Arafa, HM; Hamada, FM; Hassan, MH; Salama, SA, 2007) |
| "Uterine leiomyomas are smooth muscle cell tumors that cause irregular uterine bleeding and pregnancy loss in many reproductive-age women." | ( Bulun, SE; Cheng, YH; Innes, J; Ishikawa, H; Kim, JJ; Lin, Z; Marsh, EE; Reierstad, S; Thung, S; Utsunomiya, H; Xu, E; Xue, Q; Yin, P, 2007) |
| "Leiomyomas are the most common benign tumours and are located frequently in the middle and lower third of the oesophagus." | ( Madankumar, MV; Palanivelu, C; Rangarajan, M; Senthilkumar, R, 2008) |
| "Uterine leiomyomas are clinically significant tumours that may develop due to an altered differentiation pathway." | ( Catherino, WH; Malik, M; Webb, J, 2008) |
| "Uterine leiomyoma is the most common tumour in women with a reported incidence of 25-30%." | ( Bielawski, T; Miltyk, W; Palka, J; Surazynski, A; Wolczynski, S; Zbucka, M, 2007) |
| "Uterine leiomyomas are associated with changes in proteins present within the peritoneal fluid." | ( Anserini, P; Ferrero, S; Gillott, DJ; Grudzinskas, JG; Ragni, N; Remorgida, V, 2009) |
| "Uterine leiomyomas are the most common uterine tumors in women." | ( Asada, H; Hattori, N; Matsuoka, A; Ohgane, J; Shiota, K; Sugino, N; Taketani, T; Tamura, H; Yamagata, Y, 2008) |
| "Uterine leiomyomas are the most common benign tumours of the female genital tract, often necessitating hysterectomy." | ( Celik, H; Gurates, B; Kilic, G; Kumru, S; Parmaksiz, C; Simsek, M, 2008) |
| "Cutaneous pilar leiomyomas are rare, benign smooth muscle tumours arising from the arrector pili muscle, which usually appear as red or brown papules < 15 mm in diameter." | ( Gudgeon, PW; Merchant, W; Mitra, A; Shah, M, 2009) |
| "Uterine leiomyomas are widely prevalent and frequently cause menorrhagia." | ( Engman, M; Gemzell-Danielsson, K; Granberg, S; Lalitkumar, PG; Meng, CX; Williams, AR, 2009) |
| "Uterine leiomyoma are the most common benign tumors of the myometrium." | ( De Zen, F; Raymond, MN; Robin, P; Tanfin, Z; Vilain, G, 2009) |
| "Uterine leiomyomas are benign uterine tumors characterized by extracellular matrix remodeling, increased collagen deposition, and increased smooth muscle cell (SMC) proliferation." | ( Bulun, SE; Dyer, SN; Heinrich, DA; Marsh, EE; Mesquita, FS; Nowak, RA, 2010) |
| "Uterine leiomyomas are the most common gynecological benign tumor and greatly affect reproductive health and well-being." | ( Isobe, A; Kimura, T; Miyake, A; Morishige, K; Nishimoto, F; Sakata, M; Takeda, T; Wakabayashi, A, 2009) |
| "Although uterine leiomyomas are the most common gynaecological benign tumour and greatly affect reproductive health and well being, the pathophysiology and epidemiology of uterine leiomyomas are not well known." | ( Isobe, A; Kimura, T; Li, B; Sakata, M; Takeda, T; Tsuiji, K; Wakabayashi, A; Yaegashi, N, 2010) |
| "Uterine leiomyoma is the most common tumor of the female genital tract and the leading cause of hysterectomy." | ( Bulun, SE; Chakravarti, D; Cheng, Y; Coon, JS; Innes, J; Ishikawa, H; Kim, JJ; Lin, Z; Marsh, EE; Pearson, K; Reierstad, S; Wu, J; Yin, P, 2010) |
| "Cutaneous leiomyoma is a benign dermal tumor of smooth muscle." | ( Ghalamkarpour, F; Kani, ZA; Lotfi, S; Qaisari, M; Rahimi, H; Yousefi, M, 2010) |
| "Uterine leiomyomas are highly prevalent and symptomatic tumors of women in their reproductive years." | ( Britten, J; Catherino, WH; Malik, M; McCarthy-Keith, D; Norian, J, 2010) |
| "Leiomyomas are believed to derive from the transformation of myometrial smooth muscle cells/connective tissue fibroblasts." | ( Chegini, N, 2010) |
| "Uterine leiomyomas are highly prevalent and often symptomatic, but current medical therapies are limited." | ( Catherino, WH; Chappel, S; Davis, J; Driggers, P; Malik, M; Segars, J, 2010) |
| "Uterine leiomyomas are the most common gynaecological benign tumour and greatly affect reproductive health and wellbeing." | ( Kimura, T; Kondo, A; Li, B; Takeda, T; Tsuiji, K; Wakabayashi, A; Yaegashi, N, 2011) |
| "Uterine leiomyomas are the most common gynecological benign tumor and greatly affect reproductive health and wellbeing, but the pathophysiology and epidemiology of uterine leiomyoma are poorly understood." | ( Ito, M; Kondo, A; Li, B; Takeda, T; Tsuiji, K; Yaegashi, N, 2010) |
| "Uterine leiomyomas are the most common benign tumors of reproductive age women, but there is no effective medical therapy to data." | ( Ichigo, S; Imai, A; Matsunami, K; Suzuki, N; Takagi, H, 2011) |
| "Leiomyomas are the most common benign mesenchymal tumours of the upper gastrointestinal tract." | ( Akkiz, H; Kece, C; Ozdil, B; Sandikci, M, 2010) |
| "Uterine leiomyomas are the most common pelvic tumor, and a frequent indication of the need for gynecologic surgery." | ( Richardson, M; Spruill, L; Sullivan, S; Tarnawa, E; Underwood, P, 2011) |
| "Uterine leiomyomas are benign tumors that originate from the myometrium." | ( Kim, JJ; Sefton, EC, 2012) |
| "Uterine leiomyomas are the most common gynecological benign tumors and greatly affect reproductive health and wellbeing." | ( Kitamura, M; Kondo, A; Li, B; Takeda, T; Tsuiji, K; Wong, TF; Yaegashi, N, 2013) |
| "Uterine leiomyomas are the most common benign tumours in women, which arise from smooth muscle cells of the uterine myometrium and usually are multicentric." | ( Chiantera, V; Darwish, A; Fiebitz, A; Fritsch, M; Mechsner, S; Reichelt, U; Ruester, C; Schneider, A; Vercellino, GF, 2012) |
| "Cutaneous leiomyomas are firm, round to oval, skin-coloured to brownish papules and nodules that may present as a solitary, few discrete or multiple clustered lesions." | ( , 2013) |
| "Uterine leiomyomas are extremely common estrogen and progesterone-dependent tumors of the myometrium and cause irregular uterine bleeding, severe anemia, and recurrent pregnancy loss in 15-30% of reproductive-age women." | ( Brooks, DC; Bulun, SE; Chakravarti, D; Coon, JS; Druschitz, SA; Dyson, MT; Ercan, CM; Gottardi, CJ; Kim, JJ; Kurita, T; Ma, J; Malpani, SS; Maruyama, T; Mittal, N; Monsivais, D; Moravek, MB; Navarro, A; Ono, M; Qiang, W; Serna, VA; Yemelyanov, A; Yin, P, 2013) |
| "Uterine leiomyomas are benign tumors that develop from smooth muscle cells (SMCs)." | ( Bai, J; Hou, P; Li, Y; Luo, F; Song, J; Wang, S; Zhao, L, 2014) |
| "Uterine leiomyomas are highly prevalent benign tumors of premenopausal women and the most common indication for hysterectomy." | ( Castellucci, M; Catherino, WH; Ciarmela, P; Ciavattini, A; Giannubilo, SR; Gray, PC; Islam, MS; Janjusevic, M; Lamanna, P; Petraglia, F; Protic, O; Tranquilli, AL, 2014) |
| "Uterine leiomyoma is the most common benign gynecological tumor in women of reproductive age and represents the single most common indication for hysterectomy." | ( Carrarelli, P; Castellucci, M; Ciarmela, P; Islam, MS; Janjusevic, M; Petraglia, F; Tosti, C; Zupi, E, 2014) |
| "Uterine leiomyomas are benign tumours; recently they have been managed with embolization of the uterine arteries." | ( Agresti, P; Damiani, P; Di Felice, M; Di Giampietro, I; Marasca, E; Menichini, G; Miele, V; Moreschi, E; Pieri, S; Sessa, B; Trinci, M, 2015) |
| "Uterine leiomyoma is the ahead benign tumor of the female genital tract, which resulted in menstrual abnormalities, recurrent pregnancy loss, and other serious gynecological disorders in women." | ( Fu, Z; Ji, C; Ling, J; Wu, J; Wu, X; Xu, Q, 2015) |
| "Leiomyomas are the most common benign tumors of the uterus, frequently associated with abnormal uterine bleeding." | ( Martínez-Uribe, A; Olvera-Maldonado, AJ; Rendón-Macías, ME; Sangines-Martínez, A, 2015) |
| "Uterine leiomyomas are the most common benign tumours in women." | ( Abdel-Hafeez, M; Ali, M; Elnaggar, A; Ismail, AM; Yacoub, M, 2015) |
| "Leiomyoma is a generally benign tumour and common in the uterine smooth muscle." | ( Cordeiro, CP; da Cruz, Jde M; de Araújo, GC; Pozzatti, RR, 2015) |
| "Uterine leiomyoma are a common benign pelvic tumors composed of modified smooth muscle cells and a large amount of extracellular matrix (ECM)." | ( Barker, NM; Caplan, AI; Carrino, DA; Hurd, WW; Liu, JH; Mesiano, S; Tan, H, 2016) |
| "Uterine leiomyomas are the most common benign tumors of the female reproductive tract." | ( Adur, M; Druschitz, SA; Koohestani, F; Kurita, T; MacNeill, AL; Nowak, RA; Qiang, W; Serna, VA, 2016) |
| "Cutaneous leiomyomas are benign smooth muscle tumors that are occasionally painful." | ( Aiba, S; Kagimoto, Y; Nan, L; Numata, Y; Shimada-Ohmori, R; Yamasaki, K, 2017) |
| "Uterine leiomyomas are highly prevalent benign tumors in reproductive aged women." | ( Battino, M; Capocasa, F; Castellucci, M; Ciarmela, P; Ciavattini, A; Forbes-Hernandez, TY; Gasparrini, M; Giampieri, F; Giannubilo, SR; Greco, S; Islam, MS; Janjusevic, M; Mazzoni, L; Mezzetti, B, 2017) |
| "Uterine leiomyomas are the most common benign smooth muscle cell tumors in women." | ( Branchini, G; Brum, IS; Capp, E; Corleta, HVE; Pizzolato, LS; Sant'Anna, GDS, 2017) |
| "Endotracheal leiomyoma is a rare benign lesion, accounting for approximately 1% of tracheal tumors, and generally occurs in the lower respiratory tract." | ( Hwang, JP; Kwak, JJ; Lee, SW; Park, JM, 2017) |
| "Uterine leiomyomas are common clinical gynecological tumors, which are a major health concern for many women." | ( Hao, T; Li, Y; Liu, H; Sheng, L; Tang, N; Wang, J; Zhang, Y, 2017) |
| "Leiomyomas are estrogen dependent and tend to atrophy and shrink in size after menopause." | ( Al-Zaghal, A; Alavi, A; Høilund-Carlsen, PF; Werner, TJ, 2018) |
| "Uterine leiomyoma is the most common benign tumour in women, and an appropriate animal model for leiomyoma would be useful for exploring new therapeutic strategies." | ( Asahi, M; Ii, M; Ohmichi, M; Saito, T; Suzuki, Y; Tabata, Y; Terai, Y, 2018) |
| "Uterine leiomyoma is a benign tumor that grows within the muscle tissue of the uterus." | ( Baek, J; Cho, C; Ha, E; Kim, J; Lee, JE; Lee, S; Shin, SJ, 2018) |
| "Leiomyomas are prevalent benign smooth muscle tumors in the uterus, displaying variable degrees of FDG uptake on PET/CT." | ( Buchpiguel, CA; Carvalho, FM; Carvalho, JP; Nunes, RF; Queiroz, MA, 2019) |
| "Uterine leiomyoma is the most common benign smooth muscle tumor of uterus in women of reproductive age, with a high lifetime incidence." | ( Cui, S; Feng, Q; Liu, P; Wang, Z; Zhang, L, 2019) |
| "UAE for symptomatic leiomyoma is safe and can be an alternative to surgery in most patients with a low risk of re-intervention." | ( Kim, MD, 2019) |
| "Primary leiomyoma is a rare cause of a mass in the hand, with few reported cases to date." | ( Boczar, D; Broer, PN; Forte, AJ; Huayllani, MT; Manrique, OJ; Oliver, JD; Restrepo, DJ; Sisti, A, 2019) |
| "Leiomyoma is an important consideration when developing a differential diagnosis for primary benign masses in the hand." | ( Boczar, D; Broer, PN; Forte, AJ; Huayllani, MT; Manrique, OJ; Oliver, JD; Restrepo, DJ; Sisti, A, 2019) |
| "Uterine leiomyoma is one of the leading causes of female infertility." | ( Doroha, O; Iarotska, I; Strelko, H; Vitiuk, A, 2019) |
| "Background Uterine leiomyoma is a benign tumour of the uterine smooth muscles associated with an elevated level of inflammatory cytokines." | ( Al-Taie, A; Albasry, Z; Mohammed, NH, 2020) |
| "Although uterine leiomyomas are the most common benign uterine tumors in women, there is no effective therapy that can also preserve the uterus and maintain fertility." | ( Choi, HJ; Hwang, WY; Jung, MH; Kim, EJ; Kim, KS; Lee, JW, 2020) |
| "Rectal leiomyoma is an exceedingly rare benign lesion." | ( He, Y; Li, C; Shen, Y; Tian, Y; Wen, B, 2021) |
| "Pilar leiomyoma is the most common subtype originating from arrector pili muscles of pilosebaceous unit." | ( Arık, D; Boyuk, E; Saracoğlu, ZN, 2020) |
| "Uterine leiomyoma is the most widespread benign tumor affecting women of childbearing age." | ( Aleksandrovych, V; Gil, A; Wrona, A, 2020) |
| "Uterine leiomyoma is the most common benign pelvic tumor and the primary indication for hysterectomy." | ( Abo El-Maaty, AM; Ali, MG; Aly, MA; El Badry, SM; Mamoon, RS; Mawas, AS; Youssef, AM, 2021) |
| "Uterine leiomyoma is a benign tumor with unclear pathogenesis and inaccurate treatment." | ( Carbajo-García, MC; Cervelló, I; Corachán, A; Escrig, J; Faus, A; Ferrero, H; Monleón, J; Pellicer, A; Segura-Benitez, M, 2021) |
| "Leiomyoma is the most common benign tumor of the esophagus." | ( Bretagnol, F; Do, ML; Fingerhut, A; Leroy, J; Nguyen, ND; Nguyen, XH; Pham, DH; Quach, VK, 2022) |
| "Uterine leiomyomas are the most common neoplasm affecting women and frequently cause heavy menstrual bleeding and pain." | ( Hoshiai, H; Kudou, K; Kusumoto, T; Seki, Y; Tanimoto, M, 2021) |
| "Uterine leiomyomas are benign, estrogen-sensitive, fibrotic smooth muscle cell tumors occurring in the uterine myometrium." | ( Amitrano, AM; Bhagavath, B; DiMauro, A; Hammes, SR; Kottman, RM; Kumar, D; Minor, B; Okeke, I; Rackow, AR; Seger, C; Taya, M, 2022) |
| "Uterine leiomyomas are complex tumours with limited medical treatment options." | ( Afrin, S; Borahay, MA; El Sabeh, M; Kilic, GS; Motamedi, M; Ozpolat, B; Saada, J; Vincent, KL; Yang, J, 2022) |
| "Uterine leiomyoma is the most common benign gynecological tumor in women of reproductive age." | ( Alset, D; Butenko, EV; Pokudina, IO; Shkurat, TP, 2022) |
| "Uterine leiomyoma is one of the most common benign tumors in females." | ( Chen, J; Ma, J; Wang, Q; Yang, Z; Zhang, B; Zhang, H; Zhang, R; Zhang, Y, 2022) |
| "Cutaneous leiomyomas are known to arise from three locations viz, arrector pili muscle, dartos muscle in the scrotal sac, and smooth muscle layer of blood vessels." | ( Chandak, M; Ganjre, S; Madke, B; Pendam, M; Singh, AL, 2022) |
| "Leiomyomas are benign tumors that commonly arise from the uterus." | ( Iwamoto, S; Takeda, K; Yasumatsu, R, 2023) |
| "Leiomyomas are benign mesenchymal tumors that consist of smooth muscle cells and varying amounts of fibrous stroma." | ( Chen, M; Chi, Y; Li, Y; Xia, E, 2023) |
| "Extrauterine leiomyomas are rare and often occur in broad ligament or fallopian tube." | ( Cheng, W; Huo, L; Liu, M; Wang, P, 2023) |
| "Uterine leiomyomas are the most common benign tumors of the female reproductive system." | ( Afrin, S; Begum, UAM; Borahay, MA; Ramaiyer, M, 2023) |
| "Uterine leiomyomas are the most common benign tumors in women of childbearing age." | ( Choi, SH; Choi, SY; Han, K; Kim, JJ; Kim, MJ; Kim, S; Yang, SY; Yim, JY, 2023) |
| "Uterine leiomyomas are common hormone-responsive neoplasms that frequently cause heavy menstrual bleeding, anemia, pelvic pressure, pain, and adverse reproductive outcomes." | ( Neblett, MF; Stewart, EA, 2023) |
| "Leiomyomas are the most common benign tumors of smooth muscle origin in women." | ( Jagasyk, A; Kotowski, K; Małyszczak, P; Murawski, M; Sozański, R; Towarek, M, 2023) |
| "Uterine leiomyoma is the most common benign tumor in females of reproductive age." | ( Chen, L; Guo, S; Liu, Y; Qu, Y; Wu, H, 2023) |
| "Renal leiomyoma is a rare benign mesenchymal tumor of the kidney, which mainly originates from the renal capsule or pelvis." | ( Chen, Y; Lan, L; Liu, Y; Qiu, L; Zhang, S, 2023) |
| Excerpt | Reference |
|---|
| "However, if we may treat leiomyomas with drugs, the definite diagnosis of uterine leiomyoma is essential." | ( Fujii, S, 1992) |
| "In untreated leiomyomata, there was no significant difference between VEGF mRNA levels in the proliferative and secretory phases of the cycle." | ( Charnock-Jones, DS; Harrison-Woolrych, ML; Sharkey, AM; Smith, SK, 1995) |
| "The LA-treated leiomyomas had myxoid change (n = 2; 1." | ( Biscotti, CV; Easley, KA; Hart, WR; Prayson, RA; Sreenan, JJ; Thornton, MH, 1996) |
| "Sixty-one GnRH analogue pretreated leiomyomata and 28 untreated leiomyomata were analysed." | ( Callies, R; Kato, K; Regidor, PA; Schindler, AE; Schmidt, M, 1995) |
| "The GnRH analogue pretreated leiomyomata group showed higher levels of estrogen and progesterone receptors than the untreated group (37." | ( Callies, R; Kato, K; Regidor, PA; Schindler, AE; Schmidt, M, 1995) |
| "If pretreated leiomyomata are not removed surgically immediately after the therapy, a rapid regrowth can occur and again cause clinical symptoms." | ( Callies, R; Kato, K; Regidor, PA; Schindler, AE; Schmidt, M, 1995) |
| "The decrease in size of the treated leiomyomata occurs as an accelerated postmenopausal shrinkage because of the antiestrogenic effect of the therapy." | ( Altchek, A; Deligdisch, L; Hirschmann, S, 1997) |
| "After 12 weeks of mifepristone treatment, the leiomyoma volume decreased to 41." | ( Li, K; Yang, Y; Zheng, S, 1996) |
| "In addition, it has been used in the treatment of leiomyomata, endometriosis, advanced breast cancer, and meningioma." | ( London, SN; Mahajan, DK, 1997) |
| "It has also been used to treat leiomyomata, endometriosis, advanced breast cancer, and meningioma." | ( London, SN; Mahajan, DK, 1997) |
| "Results of this study show that LA treatment of leiomyomas results in a decrease in number of cycling cells." | ( Greenspan, DL; Kurman, RJ; Vu, K; Wu, TC; Zacur, HA, 1998) |
| "Traditional treatment for leiomyomas has been surgical removal through either hysterectomy or myomectomy." | ( Nowak, RA, 1999) |
| "Unfortunately the only effective treatments for leiomyomas and the associated abnormal uterine bleeding are surgical, involving either hysterectomy, myomectomy, or hysteroscopic removal of the tumors." | ( Nowak, RA, 2000) |
| "After 90 days of mifepristone treatment, the leiomyoma volume decreased by (37." | ( Jin, J; Wang, H, 2000) |
| "The LA effect made drug-treated leiomyomas produce less Fas and caspases 7, 9, and 10 as compared with nontreated leiomyomas." | ( Cheng, YM; Chou, CY; Hsu, KF; Huang, SC; Tang, MJ, 2002) |
| "At baseline and after treatment, uterine, leiomyoma and non-leiomyoma sizes, and leiomyoma-related symptoms were evaluated for each woman." | ( Colao, A; Lombardi, G; Nappi, C; Orio, F; Palomba, S; Panici, PL; Russo, T; Tauchmanovà, L; Zullo, F; Zupi, E, 2002) |
| "At entry and at the end of the treatment the leiomyoma volume was measured ultrasonografically and the volume change was calculated." | ( Baytur, YB; Cilaker, S; Koyuncu, FM; Kurtul, O; Lacin, S; Oruc, S; Ozbilgin, K, 2007) |
| "Compared with untreated controls, treatment of rat leiomyoma (ELT3) cells with 2-MeOHE(2) (0." | ( Al-Hendy, A; Dubey, RK; Nasr, AB; Salama, SA, 2006) |
| "TRAIL contents in untreated cultured leiomyoma cells were significantly (P < 0." | ( Chwalisz, K; DeManno, DA; Maruo, T; Ohara, N; Sasaki, H; Wang, J; Xu, Q; Yoshida, S, 2007) |
| "The reduced survival of ciglitizone treated leiomyoma cells resulted from a mechanism that involved the Fas receptor-mediated apoptosis signaling cascade." | ( Bae, I; Cha, SD; Cho, CH; Jeon, DS; Kwon, KY; Kwon, SH; Nam, DH; Ramachandran, S; Shin, SJ; Song, DK, 2007) |
| "Notably, expression levels in treated leiomyoma cells approached those found in myometrial cells." | ( Catherino, WH; Malik, M; Webb, J, 2008) |
| "In an effort to treat large uterine leiomyoma in symptomatic patients in the Gynecology Clinics of the Alzahra Teaching Hospital of Tabriz University of Medical Sciences, Tabriz, Iran, from September 2007 to November 2008, 60 candidates randomized to receive Diphereline 3." | ( Dastranj-Tabrizi, A; Farzadi, L; Gatrehsamani, F; Kazemi-Shishvan, M; Morteza, G; Ouladesahebmadarek, E; Sayyah-Melli, M; Tehrani-Gadim, S, 2009) |
| "In order not to over treat uterine leiomyoma and to avoid overlooking uterine leiomyosarcoma, a highly reliable diagnostic method has been thought." | ( Han, JY; Hyun, IY; Lee, BI; Moon, YS; Park, JH, 2010) |
| "The mean baseline volume of treated leiomyomata was 336." | ( Baik, JH; Jacobs, MA; Kim, HS; Pham, LD, 2011) |
| "Leuprolide treatment of leiomyoma cells at high concentrations (10(-5) M) did not result in an increase in protein production." | ( Britten, JL; Catherino, WH; Levy, G; Malik, M; Mendoza, M, 2012) |
| "Compared with control-treated leiomyoma cells, gestrinone significantly reduced both the expression of ERα (P<0." | ( Cao, L; Cao, Y; Guo, X; Tu, R; Xie, S; Zhang, T; Zhou, J; Zhou, X; Zhu, Y, 2012) |
| "After strawberry treatment, leiomyoma cells showed a significant decreased rate of ECAR, while OCR was unchanged in both myometrial and leiomyoma cells." | ( Battino, M; Capocasa, F; Castellucci, M; Ciarmela, P; Ciavattini, A; Forbes-Hernandez, TY; Gasparrini, M; Giampieri, F; Giannubilo, SR; Greco, S; Islam, MS; Janjusevic, M; Mazzoni, L; Mezzetti, B, 2017) |
| "Ulipristal acetate (UPA) is used to treat leiomyomas, and its effect on the endometrium has been studied in biopsy material." | ( Bergeron, C; Chamorro-Santos, C; Crespo-Lora, V; Cruz-Viruel, N; Nogales, FF, 2018) |
| "Increased MMP2 and decreased MMP9 in treated patient leiomyomas indicate both degradation of the matrix and inhibition of the pathway involved in matrix production." | ( Britten, J; Catherino, WH; Cox, J; Lewis, T; Malik, M, 2018) |
| "Among medical treatments used for leiomyoma, Selective progesterone receptor modulators (SPRM) and, in particular, Ulipristal Acetate (UPA) have been proved to be effective in the management of bleeding and myoma size reduction." | ( Benedetti Panici, P; Del Negro, V; Di Donato, V; Fischetti, M; Fracassi, A; Muzii, L; Palaia, I; Schiavi, M, 2020) |
| "From the fifteen non-treated leiomyoma group, five rats were sacrificed after Doppler ultrasound assessment (Leiomyoma), another five rats were sacrificed with the 4S group (Leiomyoma 1Wk recovery), and the last five rats were sacrificed with the recovered 4S group (Recovered leiomyoma)." | ( Abo El-Maaty, AM; Ali, MG; Aly, MA; El Badry, SM; Mamoon, RS; Mawas, AS; Youssef, AM, 2021) |