neuroprotective agent

Any compound that can be used for the treatment of neurodegenerative disorders.

ChEBI ID: 63726

Members (131)

Member	Definition	Class
((5z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4h-imidazol-4-one)	A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a (2-anilino-5-oxo-1,5-dihydro-4H-imidazol-4-ylidene)methyl group at position 5. It is an inhibitor of DYRK1A, DYRK2, CLK1, and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 muM, respectively).	leucettine L41
(3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone	A organic heterotricyclic compound that is 5-methyl-3-(morpholin-4-ylmethyl)-2,3-dihydro[1,4]oxazino[2,3,4-hi]indole substituted at position 6 by a 1-naphthylcarbonyl group.	WIN 55212-2
27-hydroxycholesterol	A 26-hydroxycholesterol in which the 25-position has R-configuration.	(25R)-cholest-5-ene-3beta,26-diol
3-(2,2,2-trimethylhydrazine)propionate	An ammonium betaine that is beta-alaninate in which one of the amino hydrogens is replaced by a trimethylamino group. A clinically used cardioprotective drug that is used for treatment of heart failure, myocardial infarction, arrhythmia, atherosclerosis and diabetes.	meldonium
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione	A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a methyl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta). An experimental compound which was being developed for the potential treatment of Alzheimer's disease.	TDZD-8
4-phenylbutyric acid, sodium salt	The organic sodium salt of 4-phenylbutyric acid. A prodrug for phenylacetate, it is used to treat urea cycle disorders.	sodium phenylbutyrate
5-methoxytryptamine	A member of the class of tryptamines that is the methyl ether derivative of serotonin.	5-methoxytryptamine
5,11-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol	A carbotetracyclic compound that is 5,6,11,12-tetrahydrochrysene substituted by hydroxy groups at positions 2 and 8 and by ethyl groups at positions 5 and 11 (the 5R,11R-stereoisomer). It is an agonist of ER-alpha and antagonist of ER-beta receptors.	(R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol
5,5-dimethyl-1-pyrroline-1-oxide	A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.	5,5-dimethyl-1-pyrroline N-oxide
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	A chromanol that is 6-hydroxychromane which is substituted by a carboxy group at position 2 and by methyl groups at positions 2, 5, 7, and 8. A cell-permeable, water-soluble analogue of vitamin E, it is used as a standard for measuring the antioxidant capacity of complex mixtures.	Trolox
6-methylthiohexyl isothiocyanate	A isothiocyanate that is hexane in which two of the terminal methyl hydrogens at positions 1 and 6 have been replaced by isothiocyanato and methylsulfanyl groups.	1-isothiocyanato-6-(methylsulfanyl)hexane
7-chlorokynurenic acid	A quinolinemonocarboxylic acid that is quinaldic acid which is substituted by a hydroxy group at position 4 and by a chlorine at position 7. It is a potent NMDA glutamate receptor antagonist which antagonizes the strychnine-insensitive glycine site of the NMDA receptor. It also prevents neurodegeneration produced by quinolinic acid.	7-chlorokynurenic acid
7-ketocholesterol	A cholestanoid that consists of cholesterol bearing an oxo substituent at position 7.	7-ketocholesterol
acteoside	A glycoside that is the alpha-L-rhamnosyl-(1->3)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid.	acteoside
albiflorin	A monoterpene glycoside with formula C23H28O11, originally isolated from the roots of Paeonia lactiflora.	albiflorin
amn082	A diamine that is ethane-1,2-diamine in which both amino groups are substituted by diphenylmethyl groups. It is an allosteric agonist of the metabotropic glutamate receptor 7 (mGluR7).	N,N'-bis(diphenylmethyl)ethane-1,2-diamine
anacardic acid	A hydroxybenzoic acid that is salicylic acid substituted by a pentadecyl group at position 6. It is a major component of cashew nut shell liquid and exhibits an extensive range of bioactivities.	anacardic acid
apelin-12 peptide	A 12 amino acid oligopeptide fragment of apelin-13 lacking the terminal L-phenylalanine residue.	apelin-12
apelin-13 peptide	A 13 amino acid oligopeptide which is the ligand for the apelin receptor (also known as the APJ receptor). It exhibits hypotensive and neuroprotective effects, and may be a potential prognostic biomarker for acute ischemic stroke and multiple sclerosis.	apelin-13
arachidonyl-2-chloroethylamide	A fatty amide obtained by the formal condensation of arachidonic acid with 2-chloroethanamine. It is a potent agonist of the CB1 receptor (Ki = 1.4 nM) and also has a low affinity for the CB2 receptor (Ki = 3100 nM).	arachidonyl-2'-chloroethylamide
argon		argon atom; argon(0)
astragaloside IV	A pentacyclic triterpenoid that is cycloastragenol having beta-D-xylopyranosyl and beta-D-glucopyranosyl residues attached at positions O-3 and O-6 respectively. It is isolated from Astragalus membranaceus var mongholicus.	astragaloside IV
astressin	A 30-membered homodetic cyclic peptide comprising the sequence D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Glu-Ala-His-Lys-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2 cyclised by an amide bridge, formed by condensation of the side-chain carboxy group of the Glu residue at position 19 and the side-chain amino group of the Lys residue at position 22.	astressin
aurapten	A member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties.	auraptene
baicalin	The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis.	baicalin
bis(7)-tacrine	A secondary amino compound consisting of two molecules of tacrine that are linked together through their exocyclic amino groups by a heptane-1,7-diyl chain. Bis(7)-tacrine is an acetylcholinesterase (AChE)inhibitor (IC50 0.40 nM, >1,000 times more potent than tacrine). It has also been found to protect against H2O2 -induced apoptosis in rat pheochromocytoma cells.	bis(7)-tacrine
caffeic acid phenethyl ester	An alkyl caffeate ester in which 2-phenylethyl is the alkyl component.	phenethyl caffeate
cannabigerol	A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species.	cannabigerol
carnosine	A dipeptide that is the N-(beta-alanyl) derivative of L-histidine.	carnosine zwitterion; carnosine
cgp 42112a	A hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist.	CGP-42112A
cilostazol	A lactam that is 3,4-dihydroquinolin-2(1H)-one in which the hydrogen at position 6 is substituted by a 4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy group.	cilostazol
creatine	A glycine derivative having methyl and amidino groups attached to the nitrogen.	creatine zwitterion; creatine
curcumin	A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.	curcumin
cyanidin	An anthocyanidin cation that is flavylium substituted at positions 3, 3', 4', 5 and 7 by hydroxy groups.	cyanidin cation
cycloheximide	A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus.	cycloheximide
cytidine diphosphate choline	A member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes.	CDP-choline
cytidine diphosphate choline	A member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes.	CDP-choline
dantrolene	The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.	dantrolene
delta(9)-tetrahydrocannabinolic acid	A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant.	Delta(9)-tetrahydrocannabinolic acid
dihydrolipoic acid	A thio-fatty acid that is reduced form of lipoic acid. A potent antioxidant shown to directly destroy superoxide, hydroperoxy and hydroxyl radicals; also has neuroprotective and anti-tumour effects.	dihydrolipoic acid
dimethyloxalylglycine	A glycine derivative that is the diester obtained by formal condensation of the carboxy groups of N-oxalylglycine with two molecules of methanol.	dimethyloxalylglycine
dizocilpine	An organic heterotetracyclic compound that is 1-methyl-8-azabicyclo[3.2.1]octane ortho-fused to two benzene rings at positions 2-3 and 6-7 (the 5S,10R-stereoisomer). It is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor and affects cognitive function, learning, and memory.	dizocilpine
dizocilpine maleate	A maleate salt obtained by reaction of dizocilpine with one equivalent of maleic acid.	dizocilpine maleate
ebselen	A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.	ebselen
epigallocatechin gallate	A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.	(-)-epigallocatechin 3-gallate
etazolate	A pyrazolopyridine that is 1H-pyrazolo[3,4-b]pyridine which is substituted at positions 1, 4, and 5 by ethyl, 2-isopropylidenehydrazino, and ethoxycarbonyl groups, respectively. A phosphodiesterase IV inhibitor with antidepressant and anxiolytic properties.	etazolate
ethoxyquin	A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.	ethoxyquin
ethylisopropylamiloride	A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group.	ethylisopropylamiloride
fangchinoline	A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from Stephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity.	fangchinoline
fasudil	An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.	fasudil
fasudil hydrochloride	A hydrochloride obtained by reaction of fasudil with one equivalent of hydrochloric acid.	fasudil hydrochloride
felbamate	The bis(carbamate ester) of 2-phenylpropane-1,3-diol. An anticonvulsant, it is used in the treatment of epilepsy.	felbamate
ferrostatin-1	An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.	ferrostatin-1
forapin	A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom.	melittin
galgravin	A member of the class of aryltetrahydrofurans carrying two 3,4-dimethoxyphenyl substituents at positions 2 and 5 as well as two methyl groups at positions 3 and 4.	galgravin
germacrone	A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities.	(E,E)-germacrone
ginsenoside rb1	A ginsenoside found in Panax ginseng and Panax japonicus var. major that is ginsenoside Rd in which the beta-D-glucopyranoside group at position 20 is replaced by a beta-D-glucopyranosyl-beta-D-glucopyranoside group.	ginsenoside Rb1
ginsenoside rb3	A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-xylopyranosyl-(1->6)-beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.	ginsenoside Rb3
ginsenoside rd	A ginsenoside found in Panax ginseng and Panax japonicus var. major that is (20S)-ginsenoside Rg3 in which the hydroxy group at position 20 has been converted to its beta-D-glucopyranoside.	ginsenoside Rd
ginsenoside re	A ginsenoside found in Panax ginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.	ginsenoside Re
ginsenoside rg1	A ginsenoside found in Panax ginseng and Panax japonicus var. major that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position.	ginsenoside Rg1
glu-asp-arg	A tripeptide composed of L-glutamic acid, L-aspartic acid, and L-arginine joined in sequence by peptide linkages.	Glu-Asp-Arg
glycerylphosphorylcholine	A member of the class of phosphocholines that is the choline ester of sn-glycero-3-phosphate. It is one of the major osmolyte in the renal medullary cells.	choline alfoscerate
glycoursodeoxycholic acid	A bile acid glycine conjugate derived from ursoodeoxycholic acid.	glycoursodeoxycholic acid
gossypin	A glycosyloxyflavone that is gossypetin attached to a beta-D-glucopyranosyl residue at position 8 via a glycosidic linkage.	gossypin
hinokiflavone	A biflavonoid that is apigenin substituted by a 4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy group at position 6. A diflavonyl ether, it is isolated from Rhus succedanea and has been found to possess significant cytotoxic potential.	hinokiflavone
huperzine a	A sesquiterpene alkaloid isolated from a club moss Huperzia serrata that has been shown to exhibit neuroprotective activity. It is also an effective inhibitor of acetylcholinesterase and has attracted interest as a therapeutic candidate for Alzheimer's disease.	huperzine A
ilomastat	An N-acyl-amino acid obtained by formal condensation of the carboxy group of (2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoic acid with the amino group of N-methyl-L-tryptophanamide. A cell permeable broad-spectrum matrix metalloproteinase (MMP) inhibitor	ilomastat
jasplakinolide	A cyclodepsipeptide isolated from Jaspis splendens and has been shown to exhibit antineoplastic activity. It is an actin polymerization and stabilization inducer.	jaspamide
kynurenic acid	A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.	kynurenic acid
l 779976	A member of the class of indoles that is (betaS)-beta-methyl-D-tryptophan in which the primary amino group undergoes formal condensation with the carboxy group of 4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylic acid and the carboxy group undegoes formal condensation with the amino group of (1R,3S)-cyclohexane-1,3-diyldimethanamine. It is a selective nonpeptidic agonist of the somatostatin subtype-2 (SST2) receptor with Ki of 0.05 nM.	L-779976
lanthionine ketimine	A member of the class of 1,4-thiazines that is 3,6-dihydro-2H-1,4-thiazine substituted by carboxy groups at positions 3 and 5. It is a natural but non-proteogenic amino acid found in human urine and brain.	lanthionine ketimine
liraglutide	A lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.	liraglutide
loganin	An iridoid monoterpenoid with formula C17H26O10 that is isolated from several plant species and exhibits neuroprotective and anti-inflammatory properties.	loganin
ly 379268	An organic heterobicyclic compound that is (1R,5S)-2-oxabicyclo[3.1.0]hexane carrying amino, carboxy, and carboxy groups at positions 4R, 4R and 6R, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 and mGluR3 (EC50 = 2.69 nM and 4.48 nM, respectively) that exhibits antipsychotic-like action in animal models of schizophrenia.	LY 379268
maysin	A flavone C-glycoside that is luteolin attached to a disaccharide residue at position 6. It has been isolated from natural product Petrorhagia velutina and Zea mays and exhibits insecticidal and neuroprotective activities.	maysin
memantine	A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.	memantine
memantine hydrochloride	A hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.	memantine hydrochloride
menatetrenone	A menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration.	menaquinone-4
methyl 3,4-dihydroxybenzoate	A methyl ester resulting from the formal condensation of the carboxy group of 3,4-dihydroxybenzoic acid with methanol.	methyl 3,4-dihydroxybenzoate
methylene blue	An organic chloride salt having 3,7-bis(dimethylamino)phenothiazin-5-ium as the counterion. A commonly used dye that also exhibits antioxidant, antimalarial, antidepressant and cardioprotective properties.	methylene blue
methylparaben	A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.	methylparaben
methylprednisolone	The 6alpha-stereoisomer of 6-methylprednisolone.	6alpha-methylprednisolone
morin	A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.	morin
n-(4-(n-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide	A sulfonamide that is a 3-methoxypyrazin-2-yl derivative of (E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide. Necrosulfonamide specifically blocks necrosis downstream of the activation of RIP3 (the receptor-interacting serine-threonine kinase 3), a key signalling molecule in the programmed necrosis (necroptosis) pathway.	necrosulfonamide
n-arachidonoyl l-serine	An N-acyl-amino acid resulting from the formal condensation of the carboxy group of arachidonic acid with the amino group of L-serine. It is an endocannabinoid-like lipid isolated from bovine brains.	N-arachidonoyl-L-serine
n-benzylhexadecanamide	A macamide resulting from the formal condensation of the carboxy group of hexadecanoic acid with benzylamine. A moderate inhibitor of fatty acid amide hydrolase.	N-benzylhexadecanamide
n,n'-dibenzhydrylethane-1,2-diamine dihydrochloride	A hydrochloride obtained by combining N,N'-bis(diphenylmethyl)ethane-1,2-diamine with two molar equivalent of hydrochloric acid.	AMN082 dihydrochloride
neriifolin	A cardenolide glycoside that is digitoxigenin in which the hydroxy goup at position 3 has been converted to its (6-deoxy-3-O-methyl-alpha-L-glucopyranoside derivative. Found in the seeds of Cerbera odollamand in Thevetia ahouia and Thevitia neriifolia.	neriifolin
niacinamide	A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.	nicotinamide
nnc 55-0396	The dihydrochloride salt of NNC 55-0396. It is a stable analogue of mibefradil and a highly selective T-type calcium channel blocker.	NNC 55-0396 dihydrochloride
NNC 55-0396 (free base)		NNC 55-0396 (free base)
norvaline	A 2-aminopentanoic acid that has S-configuration.	L-2-aminopentanoic acid zwitterion; L-2-aminopentanoic acid
notoginsenoside r1	A ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position.	notoginsenoside R1
np 031112	A member of the class of thiadiazolidines that is 1,2,4-thiadiazolidine-3,5-dione which is substituted by a naphthalen-1-yl group at position 2 and by a benzyl group at position 4. It is a non-ATP competitive inhibitor of glycogen synthase kinase 3beta (GSK3beta) and has neuroprotective effects. Currently under clinical investigation for the treatment of Alzheimer's disease and progressive supranuclear palsy.	tideglusib
oleuropein aglycone	A secoiridoid that is the methyl ester of 3,4-dihydro-2H-pyran-5-carboxylic acid which is substituted at positions 2, 3, and 4 by hydroxy, ethylidene, and carboxymethyl groups, respectively and in which the carboxylic acid moiety of the carboxymethyl substituent has been converted to the corresponding 3,4-dihydroxyphenethyl ester (the 2R,3E,4S stereoisomer). The most important phenolic compound present in olive cultivars.	oleuropein aglycone
p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe	A thirteen-membered polypeptide consisting of p-Glu, Arg, Pro, Arg, Leu, Ser, His, Lys, Gly, Pro, Met, Pro and Phe residues joined in sequence.	p-Glu-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
palmidrol	An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.	palmitoyl ethanolamide
phenylisopropyladenosine	A hydrocarbyladenosine in which adenosine is substituted at N-6 by a (2R)-1-phenylpropan-2-yl group. It is a potent adenosine A1 receptor agonist that exhibits neuroprotective and antinociceptive properties.	(-)-N(6)-(2-phenylisopropyl)adenosine; (-)-n6-(2-phenylisopropyl)adenosine
pinocembrin	A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea.	pinocembrin
pj-34	A member of the class of phenanthridines that is 5,6-dihydrophenanthridine substituted at positions 2 and 6 by (N,N-dimethylglycyl)amino and oxo groups, respectively. It is a potent inhibitor of poly(ADP-ribose) polymerases PARP1 and PARP2 (IC50 of 110 nM and 86 nM, respectively) and exhibits anti-cancer, cardioprotective and neuroprotective properties.	PJ34
pn 401	An acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity.	uridine triacetate
protectin d1	A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13E,15Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10R,17S-stereoisomer). Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1	protectin D1
pterostilbene	A stilbenol that consists of trans-stilbene bearing a hydroxy group at position 4 as well as two methoxy substituents at positions 3' and 5'.	pterostilbene
pyrrolidine dithiocarbamate	A member of the class of dithiocarbamic acids that is the N-dithiocarboxy derivative of pyrrolidine.	pyrrolidine dithiocarbamate
rasagiline	An indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor.	rasagiline
rhapontin	A rhaponticin in which the double bond adopts a trans-configuration. It possesses a range of pharmacological activities including antitumour, antiinflammatory, antilipemic and neuroprotective activities.	trans-rhaponticin
rifampin	A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei).	rifampicin zwitterion; rifampicin
rivastigmine	A carbamate ester obtained by formal condensation of the carboxy group of ethyl(methyl)carbamic acid with the phenolic OH group of 3-[(1S)-1-(dimethylamino)ethyl]phenol. A reversible cholinesterase inhibitor.	rivastigmine
ro 25-6981	A member of the class of piperidines that is 4-benzylpiperidine substituted by a 3-hydroxy-3-(4-hydroxyphenyl)-2-methylpropyl group at position 1 (the 1R,2S-stereoisomer). It is a potent antagonist of the GluN2B subunit of the N-methyl-D-aspartate (NMDA) receptor.	Ro 25-6981
rubimaillin	A benzochromene that is 2H-benzo[h]chromene which is substituted by two methyl groups at position 2, a methoxycarbonyl group at position 5, and a hydroxy group at position 6. Found in the Chinese medical plant Rubia cordifola, It has an anti-cancer effect by inhibition of TNF-alpha-induced NF-kappaB activation. It is also a dual inhibitor of acyl-CoA:cholesterol acyltransferase 1 and 2 (ACAT1 and ACAT2), but is more selective for the ACAT2 isozyme.	rubimaillin
s-methylthiocitrulline	An L-arginine derivative in which the guanidino NH2 group of L-arginine is replaced by a methylsufanyl group.	S-methyl-L-thiocitrulline
salvianolic acid B	A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza	salvianolic acid B
salvigenin	A trimethoxyflavone that is scutellarein in which the hydroxy groups at positions 4', 6, and 7 are replaced by methoxy groups.	salvigenin
sb 203580	A member of the class of imidazoles carrying 4-methylsulfinylphenyl, 4-pyridyl and 4-fluorophenyl substituents at positions 2, 4 and 5 respectively. An inhibitor of mitogen-activated protein kinase.	SB 203580
sb 415286	A member of the class of maleimides carrying 3-chloro-4-hydroxyphenylamino and 2-nitrophenyl substituents at positions 3 and 4 respectively.	SB 415286
schizandrin b	An organic heterotetracyclic compound that is found in Fructus Schisandrae and Schisandra chinensis.	(+)-schisandrin B; Deoxygomisin A
sdz eaa 494	A member of the class of piperazines that is piperazine substituted by a carboxy group at position 2R and a (1E)-1-phosphonoprop-1-en-3-yl group at position 4. It is an antagonist of N-methyl-D-aspartate receptors (NMDARs) and was in clinical development by Novartis for the treatment of cognition disorders and brain injuries (now discontinued).	midafotel
semaglutide	A polypeptide that contains a linear sequence of 31 amino acids joined together by peptide linkages. It is an agonist of glucagon-like peptide-1 receptors (GLP-1 AR) and used for the treatment of type 2 diabetes.	semaglutide
sesamin	A lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR stereoisomer). Isolated from Cinnamomum camphora, it exhibits cytotoxic activity.	(+)-sesamin
SL-327	A nitrile that is acrylonitrile in which the hydrogen attached to the same carbon as the cyano group has been replaced by an o-(trifluoromethyl)phenyl group, while the remaining hydrogens of the ethenyl group have been replaced by amino and (4-aminophenyl)sulfanyl groups. The configuration of the double bond is not specified. It is an inhibitor of MEK1 and MEK2.	SL-327
su 11248		sunitinib
ta 0910	An oligopeptide comprising of (4S)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid, L-histidine and L-prolinamide joined in sequence by peptide linkages. It is a thyrotropin-releasing hormone (TRH) analog. Its tetrahydrate form is approved in Japan for the treatment of spinal muscular atrophy.	taltirelin
tempol	A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties.	4-hydroxy-TEMPO
tenocyclidine	A tertiary amino compound that consists of cyclohexane having piperidin-1-yl and thiophen-2-yl groups attached at position 1. A dissociative anaesthetic drug with halluccinogenic and stimulant effects. Its effects are similar to those of phencyclidine (PCP, an analogue with the thienyl group replaced by phenyl), but it is rather more potent.	tenocyclidine
tetrahydroxycurcumin	A beta-diketone that is curcumin in which the two methoxy groups have been replaced by hydroxy groups. It is a metabolite of curcumin.	tetrahydroxycurcumin
tetramethylpyrazine	A member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii).	tetramethylpyrazine
theanine	A N(5)-alkylglutamine where the alkyl group is ethyl. It has been isolated from green tea.	N(5)-ethyl-L-glutamine zwitterion; N(5)-ethyl-L-glutamine
tocotrienol, alpha	A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 5, 7 and 8 and a farnesyl chain at position 2. It has been found in palm oil derived from Elaeis guineensis.	alpha-tocotrienol
ursodoxicoltaurine	A bile acid taurine conjugate derived from ursoodeoxycholic acid.	tauroursodeoxycholic acid
valproic acid	A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.	valproic acid

Research

Studies (178,307)

Timeframe	Studies, Drugs with This Role(%)	All Drugs %
pre-1990	36,328 (20.37)	18.7374
1990's	26,803 (15.03)	18.2507
2000's	38,010 (21.32)	29.6817
2010's	56,892 (31.91)	24.3611
2020's	20,274 (11.37)	2.80

Study Types

Publication Type	Studies, Drugs with this Role (%)	All Drugs (%)
Trials	11,667 (6.07%)	5.53%
Reviews	13,130 (6.83%)	6.00%
Case Studies	16,270 (8.47%)	4.05%
Observational	565 (0.29%)	0.25%
Other	150,487 (78.33%)	84.16%

Protein Targets (1,460)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	Homo sapiens (human)	Potency	23.2702	1	25
15-lipoxygenase, partial	Homo sapiens (human)	Potency	17.2427	1	13
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	Leishmania major strain Friedlin	Potency	3.7928	1	2
67.9K protein	Vaccinia virus	Potency	12.6741	2	7
acetylcholinesterase	Homo sapiens (human)	Potency	24.2214	4	21
acid sphingomyelinase	Homo sapiens (human)	Potency	26.7449	1	4
activating transcription factor 6	Homo sapiens (human)	Potency	36.2178	2	13
Adenosine receptor A1	Rattus norvegicus (Norway rat)	Potency	10.0000	1	1
aldehyde dehydrogenase 1 family, member A1	Homo sapiens (human)	Potency	23.8117	1	30
alpha-galactosidase	Homo sapiens (human)	Potency	28.0048	5	9
Alpha-synuclein	Homo sapiens (human)	Potency	11.5355	1	11
Amyloid-beta precursor protein	Homo sapiens (human)	Potency	22.7265	1	2
apical membrane antigen 1, AMA1	Plasmodium falciparum 3D7	Potency	11.4622	1	7
AR protein	Homo sapiens (human)	Potency	17.2591	12	98
aryl hydrocarbon receptor	Homo sapiens (human)	Potency	24.9302	3	26
arylsulfatase A	Homo sapiens (human)	Potency	13.4847	1	7
ATAD5 protein, partial	Homo sapiens (human)	Potency	13.9937	4	18
Ataxin-2	Homo sapiens (human)	Potency	18.5019	2	15
ATP-dependent phosphofructokinase	Trypanosoma brucei brucei TREU927	Potency	8.8146	5	17
ATPase family AAA domain-containing protein 5	Homo sapiens (human)	Potency	20.9901	2	15
atrial natriuretic peptide receptor 1 precursor	Homo sapiens (human)	Potency	14.7637	1	3
atrial natriuretic peptide receptor 2 precursor	Homo sapiens (human)	Potency	26.1216	1	2
beta-2 adrenergic receptor	Homo sapiens (human)	Potency	11.4012	2	2
Bloom syndrome protein isoform 1	Homo sapiens (human)	Potency	12.5921	2	15
BRCA1	Homo sapiens (human)	Potency	17.7828	1	1
bromodomain adjacent to zinc finger domain 2B	Homo sapiens (human)	Potency	46.8458	1	14
C-terminal-binding protein 1	Homo sapiens (human)	Potency	16.9469	1	1
caspase 7, apoptosis-related cysteine protease	Homo sapiens (human)	Potency	19.1717	1	2
caspase-1 isoform alpha precursor	Homo sapiens (human)	Potency	29.0941	1	3
caspase-3	Cricetulus griseus (Chinese hamster)	Potency	72.8099	1	3
caspase-3	Homo sapiens (human)	Potency	19.1717	1	2
Caspase-7	Cricetulus griseus (Chinese hamster)	Potency	72.8099	1	3
Caspase-7	Homo sapiens (human)	Potency	14.2191	1	2
Cellular tumor antigen p53	Homo sapiens (human)	Potency	25.9997	3	24
cellular tumor antigen p53 isoform a	Homo sapiens (human)	Potency	17.1765	2	7
Chain A, 2-oxoglutarate Oxygenase	Homo sapiens (human)	Potency	25.6977	1	26
Chain A, ATP-DEPENDENT DNA HELICASE Q1	Homo sapiens (human)	Potency	20.2224	2	7
Chain A, Beta-lactamase	Escherichia coli K-12	Potency	22.5455	2	9
Chain A, Breast cancer type 1 susceptibility protein	Homo sapiens (human)	Potency	5.0119	1	3
Chain A, Cruzipain	Trypanosoma cruzi	Potency	30.0335	2	6
Chain A, Ferritin light chain	Equus caballus (horse)	Potency	26.5076	2	13
Chain A, HADH2 protein	Homo sapiens (human)	Potency	17.9864	2	32
Chain A, JmjC domain-containing histone demethylation protein 3A	Homo sapiens (human)	Potency	57.9438	1	14
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	Homo sapiens (human)	Potency	16.4640	2	24
Chain A, Putative fructose-1,6-bisphosphate aldolase	Giardia intestinalis	Potency	21.4513	3	16
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	Homo sapiens (human)	Potency	16.5252	2	21
Chain B, HADH2 protein	Homo sapiens (human)	Potency	17.9864	2	32
chaperonin GroEL	Methanococcus maripaludis S2	Potency	100.0000	1	1
chaperonin-containing TCP-1 beta subunit homolog	Homo sapiens (human)	Potency	22.3872	1	1
chromobox protein homolog 1	Homo sapiens (human)	Potency	34.9093	2	20
CREB-binding protein	Homo sapiens (human)	Potency	5.4415	3	3
cytochrome P450 2C19 precursor	Homo sapiens (human)	Potency	12.8640	1	9
cytochrome P450 2C9 precursor	Homo sapiens (human)	Potency	17.5202	1	11
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	12.1309	1	9
cytochrome P450 2D6	Homo sapiens (human)	Potency	11.9654	1	7
cytochrome P450 2D6 isoform 1	Homo sapiens (human)	Potency	17.4859	1	9
cytochrome P450 3A4 isoform 1	Homo sapiens (human)	Potency	15.3207	2	48
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	11.4590	1	8
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	Homo sapiens (human)	Potency	18.5490	1	14
D(1A) dopamine receptor	Homo sapiens (human)	Potency	10.4436	3	11
D(1A) dopamine receptor	Sus scrofa (pig)	Potency	10.7469	1	3
Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)	Potency	25.1189	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	Homo sapiens (human)	Potency	26.2564	1	5
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	Homo sapiens (human)	Potency	27.2454	2	3
DNA polymerase beta	Homo sapiens (human)	Potency	12.9714	1	8
DNA polymerase eta isoform 1	Homo sapiens (human)	Potency	52.9872	1	6
DNA polymerase III, partial	Bacillus subtilis	Potency	11.8160	1	2
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	52.6760	2	17
DNA polymerase kappa isoform 1	Homo sapiens (human)	Potency	25.2048	1	17
dopamine D1 receptor	Homo sapiens (human)	Potency	13.8373	1	3
endonuclease IV	Escherichia coli	Potency	13.7521	1	3
Endothelin receptor type B	Rattus norvegicus (Norway rat)	Potency	22.3872	1	1
Endothelin-1 receptor	Rattus norvegicus (Norway rat)	Potency	22.3872	1	1
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	22.6219	11	94
estrogen receptor 2 (ER beta)	Homo sapiens (human)	Potency	13.6866	2	6
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	14.0075	10	68
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	15.4611	1	45
EWS/FLI fusion protein	Homo sapiens (human)	Potency	18.7629	4	28
eyes absent homolog 2 isoform a	Homo sapiens (human)	Potency	8.4936	1	1
farnesoid X nuclear receptor	Homo sapiens (human)	Potency	35.0795	4	13
flap endonuclease 1	Homo sapiens (human)	Potency	39.4580	2	16
fructose-bisphosphate aldolase A	Oryctolagus cuniculus (rabbit)	Potency	74.1396	1	2
Fumarate hydratase	Homo sapiens (human)	Potency	26.1931	1	5
G	Vesicular stomatitis virus	Potency	12.1309	1	9
GABA theta subunit	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
galactokinase	Homo sapiens (human)	Potency	10.0000	1	1
GALC protein	Homo sapiens (human)	Potency	0.7079	1	2
Gamma-aminobutyric acid receptor subunit alpha-1	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit beta-1	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit beta-2	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit beta-3	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit delta	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit epsilon	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit gamma-1	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit gamma-2	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit gamma-3	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
Gamma-aminobutyric acid receptor subunit pi	Rattus norvegicus (Norway rat)	Potency	15.4282	1	25
geminin	Homo sapiens (human)	Potency	14.1043	4	48
GLI family zinc finger 3	Homo sapiens (human)	Potency	15.5458	3	36
glp-1 receptor, partial	Homo sapiens (human)	Potency	10.3004	1	11
GLS protein	Homo sapiens (human)	Potency	10.9099	2	22
glucocerebrosidase	Homo sapiens (human)	Potency	30.3112	1	14
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	45.6556	4	31
glucokinase regulatory protein	Homo sapiens (human)	Potency	20.4297	2	4
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	20.4755	1	8
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Glycoprotein hormones alpha chain	Homo sapiens (human)	Potency	0.5012	1	1
GTP-binding nuclear protein Ran isoform 1	Homo sapiens (human)	Potency	22.2175	1	4
Guanine nucleotide-binding protein G	Homo sapiens (human)	Potency	12.1897	2	5
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	Homo sapiens (human)	Potency	12.5893	1	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	Homo sapiens (human)	Potency	11.7350	2	9
heat shock protein beta-1	Homo sapiens (human)	Potency	46.2502	2	10
hemoglobin subunit beta	Homo sapiens (human)	Potency	39.8107	1	1
hexokinase-4 isoform 1	Homo sapiens (human)	Potency	20.4297	2	4
Histamine H2 receptor	Cavia porcellus (domestic guinea pig)	Potency	14.0566	2	63
histone acetyltransferase KAT2A isoform 1	Homo sapiens (human)	Potency	13.1993	1	8
histone deacetylase 9 isoform 3	Homo sapiens (human)	Potency	18.5888	2	5
Histone H2A.x	Cricetulus griseus (Chinese hamster)	Potency	31.9662	2	12
histone-lysine N-methyltransferase 2A isoform 2 precursor	Homo sapiens (human)	Potency	39.1902	1	6
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	12.1309	1	9
huntingtin isoform 2	Homo sapiens (human)	Potency	22.5284	1	6
hypothetical protein, conserved	Trypanosoma brucei	Potency	19.9534	4	10
hypoxia-inducible factor 1 alpha subunit	Homo sapiens (human)	Potency	42.0152	2	10
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	Homo sapiens (human)	Potency	11.4922	2	14
IDH1	Homo sapiens (human)	Potency	16.1018	1	12
importin subunit beta-1 isoform 1	Homo sapiens (human)	Potency	28.0621	2	7
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	12.1309	1	18
Inositol monophosphatase 1	Rattus norvegicus (Norway rat)	Potency	7.4763	1	6
Integrin alpha-IIb	Homo sapiens (human)	Potency	27.8298	1	2
Integrin beta-3	Homo sapiens (human)	Potency	27.8298	1	2
Interferon beta	Homo sapiens (human)	Potency	14.8817	3	34
interleukin 8	Homo sapiens (human)	Potency	75.3096	1	3
isocitrate dehydrogenase 1, partial	Homo sapiens (human)	Potency	50.7856	1	3
lamin isoform A-delta10	Homo sapiens (human)	Potency	9.2025	2	15
lethal factor (plasmid)	Bacillus anthracis str. A2012	Potency	10.9167	1	14
lethal(3)malignant brain tumor-like protein 1 isoform I	Homo sapiens (human)	Potency	23.7358	1	2
Luciferase	Photinus pyralis (common eastern firefly)	Potency	26.9489	4	19
luciferase	Photuris pensylvanica (Pennsylania firefly)	Potency	16.7324	3	6
luteinizing hormone receptor	Homo sapiens (human)	Potency	84.9214	1	1
lysosomal alpha-glucosidase preproprotein	Homo sapiens (human)	Potency	13.2997	2	7
M-phase phosphoprotein 8	Homo sapiens (human)	Potency	30.3448	1	11
Microtubule-associated protein tau	Homo sapiens (human)	Potency	12.8271	2	35
mitogen-activated protein kinase 1	Homo sapiens (human)	Potency	19.2701	2	17
muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	Potency	6.9975	2	12
muscleblind-like protein 1 isoform 1	Homo sapiens (human)	Potency	30.3093	1	7
neuropeptide S receptor isoform A	Homo sapiens (human)	Potency	6.1802	3	9
NFKB1 protein, partial	Homo sapiens (human)	Potency	8.2084	2	14
nonstructural protein 1	Influenza A virus (A/WSN/1933(H1N1))	Potency	7.4542	1	9
NPC intracellular cholesterol transporter 1 precursor	Homo sapiens (human)	Potency	27.0829	1	5
Nrf2	Homo sapiens (human)	Potency	20.8964	2	6
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	66.9046	4	40
nuclear factor erythroid 2-related factor 2 isoform 2	Homo sapiens (human)	Potency	9.2785	2	8
nuclear factor NF-kappa-B p105 subunit isoform 1	Homo sapiens (human)	Potency	21.5933	1	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	Homo sapiens (human)	Potency	37.1337	1	3
Nuclear receptor ROR-gamma	Homo sapiens (human)	Potency	28.5731	1	5
nuclear receptor ROR-gamma isoform 1	Mus musculus (house mouse)	Potency	16.0509	2	51
nuclear receptor subfamily 1, group I, member 2	Rattus norvegicus (Norway rat)	Potency	1.5849	1	1
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	20.8267	3	33
Ornithine decarboxylase	Rattus norvegicus (Norway rat)	Potency	5.0050	1	2
P53	Homo sapiens (human)	Potency	28.1838	1	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	Homo sapiens (human)	Potency	78.1522	1	8
Parkin	Homo sapiens (human)	Potency	27.2873	2	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	Potency	59.7050	2	6
peripheral myelin protein 22	Rattus norvegicus (Norway rat)	Potency	21.8286	2	7
peripheral myelin protein 22 isoform 1	Homo sapiens (human)	Potency	58.1560	1	7
peroxisome proliferator activated receptor gamma	Homo sapiens (human)	Potency	62.6405	5	29
peroxisome proliferator-activated receptor delta	Homo sapiens (human)	Potency	29.4753	5	16
phosphoglycerate kinase	Trypanosoma brucei brucei TREU927	Potency	20.8584	2	2
phosphopantetheinyl transferase	Bacillus subtilis	Potency	40.5054	3	24
PINK1	Homo sapiens (human)	Potency	35.6221	1	3
plasminogen precursor	Mus musculus (house mouse)	Potency	6.2058	1	8
polyprotein	Zika virus	Potency	26.1931	1	5
polyunsaturated fatty acid lipoxygenase ALOX12	Homo sapiens (human)	Potency	16.3715	1	8
Polyunsaturated fatty acid lipoxygenase ALOX15B	Homo sapiens (human)	Potency	10.2468	1	15
potassium voltage-gated channel subfamily H member 2 isoform d	Homo sapiens (human)	Potency	16.1367	1	10
PPM1D protein	Homo sapiens (human)	Potency	15.7059	1	14
pregnane X nuclear receptor	Homo sapiens (human)	Potency	26.3093	3	13
pregnane X receptor	Rattus norvegicus (Norway rat)	Potency	124.4425	1	7
progesterone receptor	Homo sapiens (human)	Potency	29.7102	3	16
putative alpha-glucosidase	Oryza sativa Japonica Group (Japanese rice)	Potency	39.8107	1	1
pyruvate kinase	Leishmania mexicana mexicana	Potency	16.8088	5	7
pyruvate kinase PKM isoform a	Homo sapiens (human)	Potency	16.4427	4	10
pyruvate kinase PKM isoform b	Homo sapiens (human)	Potency	5.0050	2	4
Rap guanine nucleotide exchange factor 3	Homo sapiens (human)	Potency	67.5438	2	4
RAR-related orphan receptor gamma	Mus musculus (house mouse)	Potency	20.1912	2	18
ras-related protein Rab-9A	Homo sapiens (human)	Potency	32.3304	1	6
regulator of G-protein signaling 4	Homo sapiens (human)	Potency	9.9653	1	11
relaxin receptor 1 isoform 1	Homo sapiens (human)	Potency	8.3558	2	2
relaxin receptor 2 isoform 1	Homo sapiens (human)	Potency	43.6206	1	1
retinoic acid nuclear receptor alpha variant 1	Homo sapiens (human)	Potency	25.7628	3	34
retinoid X nuclear receptor alpha	Homo sapiens (human)	Potency	20.2463	4	31
RGS12	Homo sapiens (human)	Potency	12.5893	1	1
serine-protein kinase ATM isoform a	Homo sapiens (human)	Potency	14.8981	4	5
serine/threonine-protein kinase mTOR isoform 1	Homo sapiens (human)	Potency	14.1874	3	13
serine/threonine-protein kinase PLK1	Homo sapiens (human)	Potency	22.4850	1	4
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	Potency	5.7988	1	1
SMAD family member 2	Homo sapiens (human)	Potency	33.2578	3	8
SMAD family member 3	Homo sapiens (human)	Potency	33.2578	3	8
Smad3	Homo sapiens (human)	Potency	18.3652	1	15
snurportin-1	Homo sapiens (human)	Potency	28.0621	2	7
Sodium channel protein type 1 subunit alpha	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Sodium channel protein type 2 subunit alpha	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Sodium channel protein type 3 subunit alpha	Rattus norvegicus (Norway rat)	Potency	5.7988	1	1
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	Potency	34.3555	1	6
survival motor neuron protein isoform d	Homo sapiens (human)	Potency	13.1627	1	15
T cell receptor, partial	Homo sapiens (human)	Potency	6.2841	1	1
TAR DNA-binding protein 43	Homo sapiens (human)	Potency	19.4563	1	10
TDP1 protein	Homo sapiens (human)	Potency	15.3825	2	94
thioredoxin glutathione reductase	Schistosoma mansoni	Potency	36.4499	1	7
thioredoxin reductase	Rattus norvegicus (Norway rat)	Potency	25.9686	4	35
Thrombopoietin	Homo sapiens (human)	Potency	6.2308	2	12
thyroid hormone receptor beta isoform 2	Rattus norvegicus (Norway rat)	Potency	26.2518	3	35
thyroid hormone receptor beta isoform a	Homo sapiens (human)	Potency	33.3458	4	10
thyroid stimulating hormone receptor	Homo sapiens (human)	Potency	20.8871	7	39
thyrotropin-releasing hormone receptor	Homo sapiens (human)	Potency	27.7247	1	1
transcriptional regulator ERG isoform 3	Homo sapiens (human)	Potency	15.8489	1	1
transient receptor potential cation channel subfamily V member 1	Homo sapiens (human)	Potency	25.7877	1	2
TSHR protein	Homo sapiens (human)	Potency	15.5035	2	2
tumor susceptibility gene 101 protein	Homo sapiens (human)	Potency	19.9526	1	1
tyrosine-protein kinase Yes	Homo sapiens (human)	Potency	5.4792	1	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	Homo sapiens (human)	Potency	21.8058	2	2
urokinase plasminogen activator surface receptor precursor	Mus musculus (house mouse)	Potency	6.2058	1	8
urokinase-type plasminogen activator precursor	Mus musculus (house mouse)	Potency	6.2058	1	8
USP1 protein, partial	Homo sapiens (human)	Potency	43.4111	2	18
v-jun sarcoma virus 17 oncogene homolog (avian)	Homo sapiens (human)	Potency	19.6715	2	16
vasopressin V1b receptor	Homo sapiens (human)	Potency	21.8621	1	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	Homo sapiens (human)	Potency	40.1969	5	15
vitamin D3 receptor isoform VDRA	Homo sapiens (human)	Potency	37.7717	1	15
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	20.4755	1	8
Vpr	Human immunodeficiency virus 1	Potency	25.3621	1	3

Inhibition Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
[tau protein] kinase	Oryctolagus cuniculus (rabbit)	IC50	2.0000	1	1
[Tau protein] kinase	Sus scrofa (pig)	IC50	2.9350	4	4
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	Homo sapiens (human)	IC50	5.9775	2	4
10 kDa chaperonin	Escherichia coli	IC50	27.5800	4	8
10 kDa heat shock protein, mitochondrial	Homo sapiens (human)	IC50	30.4000	2	4
17-beta-hydroxysteroid dehydrogenase type 2	Homo sapiens (human)	IC50	1.7300	1	1
3-oxoacyl-[acyl-carrier-protein] reductase	Plasmodium falciparum 3D7	IC50	0.3200	1	1
3-oxoacyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	1.3000	1	2
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	Homo sapiens (human)	IC50	7.2833	1	6
4-hydroxyphenylpyruvate dioxygenase	Arabidopsis thaliana (thale cress)	IC50	73.0000	1	1
5-hydroxytryptamine receptor 1A	Homo sapiens (human)	Ki	0.0032	1	1
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	Ki	0.0048	5	5
5-hydroxytryptamine receptor 1B	Homo sapiens (human)	Ki	0.0035	1	1
5-hydroxytryptamine receptor 1B	Rattus norvegicus (Norway rat)	Ki	0.2015	3	4
5-hydroxytryptamine receptor 1D	Homo sapiens (human)	Ki	0.0054	1	1
5-hydroxytryptamine receptor 1D	Rattus norvegicus (Norway rat)	Ki	0.0020	1	1
5-hydroxytryptamine receptor 1F	Rattus norvegicus (Norway rat)	Ki	0.0020	1	1
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	Ki	0.1524	2	2
5-hydroxytryptamine receptor 2A	Rattus norvegicus (Norway rat)	Ki	0.5571	7	7
5-hydroxytryptamine receptor 2B	Rattus norvegicus (Norway rat)	Ki	0.5571	7	7
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	Ki	0.0450	1	1
5-hydroxytryptamine receptor 2C	Rattus norvegicus (Norway rat)	Ki	0.5500	8	8
5-hydroxytryptamine receptor 4	Homo sapiens (human)	Ki	0.1362	2	2
5-hydroxytryptamine receptor 6	Homo sapiens (human)	Ki	0.0465	3	3
5-hydroxytryptamine receptor 7	Cavia porcellus (domestic guinea pig)	IC50	27.2000	1	2
5-hydroxytryptamine receptor 7	Homo sapiens (human)	IC50	200.0000	1	1
5-hydroxytryptamine receptor 7	Homo sapiens (human)	Ki	0.0035	2	2
5-hydroxytryptamine receptor 7	Rattus norvegicus (Norway rat)	Ki	0.0009	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	IC50	0.1580	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	IC50	0.0617	1	1
6-phosphogluconate dehydrogenase, decarboxylating	Homo sapiens (human)	IC50	0.7200	1	1
60 kDa chaperonin	Escherichia coli K-12	IC50	250.0000	1	3
60 kDa chaperonin	Escherichia coli	IC50	27.5800	4	8
60 kDa heat shock protein, mitochondrial	Homo sapiens (human)	IC50	30.4000	2	4
72 kDa type IV collagenase	Homo sapiens (human)	IC50	2.6670	15	20
72 kDa type IV collagenase	Homo sapiens (human)	Ki	0.0004	3	3
A disintegrin and metalloproteinase with thrombospondin motifs 4	Homo sapiens (human)	IC50	0.4800	1	1
A disintegrin and metalloproteinase with thrombospondin motifs 5	Homo sapiens (human)	IC50	0.5000	1	1
Acetylcholine receptor subunit epsilon	Rattus norvegicus (Norway rat)	IC50	9.0000	1	1
Acetylcholinesterase	Electrophorus electricus (electric eel)	IC50	43.6823	45	51
Acetylcholinesterase	Homo sapiens (human)	IC50	60.4402	69	74
Acetylcholinesterase	Mus musculus (house mouse)	IC50	4.5904	5	5
Acetylcholinesterase	Rattus norvegicus (Norway rat)	IC50	3.9418	27	30
Acetylcholinesterase	Tetronarce californica (Pacific electric ray)	IC50	187.2000	1	1
Acetylcholinesterase	Homo sapiens (human)	Ki	0.0016	2	4
Acetylcholinesterase	Mus musculus (house mouse)	Ki	5.6800	1	1
Acetylcholinesterase	Bos taurus (cattle)	IC50	0.3600	2	2
Acetylcholinesterase	Bos taurus (cattle)	Ki	0.0013	4	4
Acyl carrier protein, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
Acyl-CoA desaturase 1	Rattus norvegicus (Norway rat)	IC50	1.7100	1	1
Adenosine receptor A1	Homo sapiens (human)	IC50	1.8900	2	2
Adenosine receptor A1	Rattus norvegicus (Norway rat)	IC50	0.0294	4	5
Adenosine receptor A1	Bos taurus (cattle)	Ki	0.0082	3	3
Adenosine receptor A1	Homo sapiens (human)	Ki	0.5538	4	4
Adenosine receptor A1	Rattus norvegicus (Norway rat)	Ki	0.0248	18	21
Adenosine receptor A2a	Homo sapiens (human)	IC50	6.0680	1	1
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	IC50	0.2898	2	4
Adenosine receptor A2a	Homo sapiens (human)	Ki	1.6852	4	4
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	Ki	2.4882	12	13
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	IC50	0.2899	2	4
Adenosine receptor A2b	Homo sapiens (human)	Ki	1.7000	1	1
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	Ki	2.6838	11	12
Adenosine receptor A3	Rattus norvegicus (Norway rat)	IC50	0.0497	1	2
Adenosine receptor A3	Homo sapiens (human)	Ki	8.5083	4	4
Adenosine receptor A3	Rattus norvegicus (Norway rat)	Ki	0.0166	5	5
Adenylate cyclase type 5	Rattus norvegicus (Norway rat)	Ki	0.0087	1	2
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	Homo sapiens (human)	IC50	21.8000	1	1
Aldo-keto reductase family 1 member A1	Bos taurus (cattle)	IC50	57.4000	1	1
Aldo-keto reductase family 1 member A1	Homo sapiens (human)	IC50	50.0500	2	2
Aldo-keto reductase family 1 member A1	Rattus norvegicus (Norway rat)	IC50	53.1000	2	2
Aldo-keto reductase family 1 member B1	Homo sapiens (human)	IC50	2.0650	2	2
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	IC50	47.3812	6	6
Aldo-keto reductase family 1 member B1	Homo sapiens (human)	Ki	0.9500	1	1
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	Ki	3.7560	1	1
Aldo-keto reductase family 1 member B10	Homo sapiens (human)	IC50	0.1833	3	3
Aldo-keto reductase family 1 member B10	Homo sapiens (human)	Ki	0.0460	1	1
Aldo-keto reductase family 1 member B7	Rattus norvegicus (Norway rat)	IC50	56.1000	1	1
Aldo-keto reductase family 1 member C1	Homo sapiens (human)	IC50	21.1200	2	2
Aldo-keto reductase family 1 member C2	Homo sapiens (human)	IC50	15.8800	2	2
Aldo-keto reductase family 1 member C3	Homo sapiens (human)	IC50	2.7050	2	2
Aldo-keto reductase family 1 member C4	Homo sapiens (human)	IC50	5.2750	2	2
ALK tyrosine kinase receptor	Homo sapiens (human)	IC50	1.1773	2	2
alkaline phosphatase, germ cell type preproprotein	Homo sapiens (human)	IC50	100.0000	1	1
alkaline phosphatase, intestinal	Homo sapiens (human)	IC50	100.0000	1	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	Homo sapiens (human)	IC50	100.0000	1	1
Alpha-(1,3)-fucosyltransferase 7	Homo sapiens (human)	IC50	7.2833	1	6
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	2.9500	1	2
Alpha-1A adrenergic receptor	Homo sapiens (human)	Ki	0.1800	1	1
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	Ki	0.0210	1	1
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	2.9500	1	2
Alpha-1B adrenergic receptor	Homo sapiens (human)	Ki	0.1800	1	1
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	IC50	2.9500	1	2
Alpha-1D adrenergic receptor	Homo sapiens (human)	Ki	0.1800	1	1
Alpha-amylase 1A	Homo sapiens (human)	IC50	1,400.0000	1	1
Alpha-synuclein	Homo sapiens (human)	IC50	46.0640	4	5
Amine oxidase [flavin-containing] A	Homo sapiens (human)	IC50	59.4436	45	46
Amine oxidase [flavin-containing] A	Mus musculus (house mouse)	IC50	0.0000	1	1
Amine oxidase [flavin-containing] A	Homo sapiens (human)	Ki	4.5300	5	7
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)	IC50	80.6986	4	5
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)	Ki	0.0142	1	1
Amine oxidase [flavin-containing] B	Homo sapiens (human)	IC50	3.8622	57	59
Amine oxidase [flavin-containing] B	Mus musculus (house mouse)	IC50	0.3000	2	2
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)	IC50	1.9798	6	8
Amine oxidase [flavin-containing] B	Bos taurus (cattle)	Ki	0.5000	1	1
Amine oxidase [flavin-containing] B	Homo sapiens (human)	Ki	4.4222	8	10
Amine oxidase [flavin-containing] B	Mus musculus (house mouse)	Ki	0.5000	1	1
Amine oxidase [flavin-containing] B	Rattus norvegicus (Norway rat)	Ki	0.1739	3	3
Aminopeptidase N	Homo sapiens (human)	IC50	15.5000	1	1
Aminopeptidase N	Sus scrofa (pig)	IC50	15.5000	1	1
Amyloid-beta precursor protein	Homo sapiens (human)	IC50	12.2806	39	40
Androgen receptor	Rattus norvegicus (Norway rat)	IC50	226.6300	2	2
Androgen receptor	Rattus norvegicus (Norway rat)	Ki	17.7860	1	1
Angiopoietin-1 receptor	Homo sapiens (human)	IC50	10.0090	2	2
Angiotensin-converting enzyme 2	Homo sapiens (human)	IC50	1.1100	1	2
Anthrax toxin receptor 2	Homo sapiens (human)	IC50	300.0000	1	1
AP2-associated protein kinase 1	Homo sapiens (human)	IC50	0.0462	2	2
Apelin receptor	Homo sapiens (human)	IC50	0.0012	1	1
Apelin receptor	Homo sapiens (human)	Ki	0.0007	6	6
Apelin receptor	Rattus norvegicus (Norway rat)	Ki	0.0003	1	1
Apoptosis regulator Bcl-2	Homo sapiens (human)	IC50	0.4500	1	1
Apoptosis regulator Bcl-2	Homo sapiens (human)	Ki	0.3622	2	2
Apoptotic peptidase activating factor 1	Homo sapiens (human)	IC50	57.7500	2	2
Arginase	Leishmania amazonensis	Ki	0.7000	1	1
Arginase-1	Bos taurus (cattle)	IC50	285.0000	1	1
Aromatase	Homo sapiens (human)	IC50	2.1795	2	4
Arrestin, beta 1	Homo sapiens (human)	IC50	1.5240	1	1
Arylacetamide deacetylase	Homo sapiens (human)	Ki	300.0000	1	1
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	IC50	111.6667	1	3
ATP-dependent translocase ABCB1	Homo sapiens (human)	IC50	14.0822	3	3
Aurora kinase A	Homo sapiens (human)	IC50	1.8370	1	1
Aurora kinase B	Homo sapiens (human)	IC50	7.3675	2	4
Bcl-2-like protein 1	Homo sapiens (human)	IC50	0.5900	1	1
Bcl-2-like protein 10	Homo sapiens (human)	IC50	0.3600	1	1
Bcl-2-like protein 2	Homo sapiens (human)	IC50	2.3300	1	1
Bcl-2-related protein A1	Homo sapiens (human)	IC50	1.7900	1	1
Bcl2-associated agonist of cell death	Homo sapiens (human)	Ki	0.4900	1	1
Beta lactamase (plasmid)	Pseudomonas aeruginosa	IC50	7.7510	1	1
Beta-adrenergic receptor kinase 1	Bos taurus (cattle)	IC50	130.0000	1	1
Beta-casein	Bos taurus (cattle)	IC50	100.0000	1	3
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	2.8100	2	3
Beta-secretase 1	Homo sapiens (human)	IC50	68.5497	10	11
BH3-interacting domain death agonist	Homo sapiens (human)	IC50	1.0733	6	6
Bifunctional epoxide hydrolase 2	Homo sapiens (human)	IC50	2.2590	6	6
Bifunctional epoxide hydrolase 2	Mus musculus (house mouse)	IC50	0.4220	1	1
Bifunctional epoxide hydrolase 2	Rattus norvegicus (Norway rat)	IC50	0.3700	1	1
Bile acid receptor	Homo sapiens (human)	IC50	49.8550	2	2
Bile salt export pump	Homo sapiens (human)	IC50	432.4689	6	18
Bile salt export pump	Rattus norvegicus (Norway rat)	IC50	678.2333	1	3
Bile salt export pump	Rattus norvegicus (Norway rat)	Ki	11.9000	1	1
Breakpoint cluster region protein	Homo sapiens (human)	IC50	10.0000	1	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	IC50	26.1260	5	5
C-C chemokine receptor type 2	Homo sapiens (human)	IC50	35.0000	2	2
C-C motif chemokine 2	Homo sapiens (human)	IC50	6.9183	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	Homo sapiens (human)	IC50	1,000.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	Homo sapiens (human)	Ki	60.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Homo sapiens (human)	IC50	1,000.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	Homo sapiens (human)	Ki	60.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	Homo sapiens (human)	IC50	1,000.0000	1	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	Homo sapiens (human)	Ki	60.0000	1	1
cAMP-dependent protein kinase catalytic subunit alpha	Bos taurus (cattle)	IC50	21.4434	2	15
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	IC50	27.2900	2	2
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Ki	0.4600	1	1
cAMP-dependent protein kinase catalytic subunit alpha	Mus musculus (house mouse)	Ki	0.4950	1	2
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	IC50	27.2900	2	2
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Ki	0.4600	1	1
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	IC50	27.2900	2	2
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Ki	0.4600	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	IC50	0.3900	1	1
Canalicular multispecific organic anion transporter 1	Homo sapiens (human)	IC50	106.3333	1	3
Canalicular multispecific organic anion transporter 1	Rattus norvegicus (Norway rat)	Ki	7.9500	1	1
Cannabinoid receptor 1	Homo sapiens (human)	IC50	0.4579	9	9
Cannabinoid receptor 1	Homo sapiens (human)	Ki	1.3418	73	82
Cannabinoid receptor 1	Mus musculus (house mouse)	Ki	0.0186	4	4
Cannabinoid receptor 1	Rattus norvegicus (Norway rat)	Ki	152,001.9136	6	6
Cannabinoid receptor 2	Mus musculus (house mouse)	Ki	0.0060	1	1
Cannabinoid receptor 2	Homo sapiens (human)	IC50	0.5820	6	6
Cannabinoid receptor 2	Homo sapiens (human)	Ki	0.9041	72	81
Carbonic anhydrase 1	Homo sapiens (human)	Ki	9.5850	2	6
Carbonic anhydrase 12	Homo sapiens (human)	Ki	0.8900	1	2
Carbonic anhydrase 14	Homo sapiens (human)	Ki	2.4950	1	2
Carbonic anhydrase 2	Homo sapiens (human)	Ki	9.6967	2	6
Carbonic anhydrase 3	Bos taurus (cattle)	Ki	13.5500	1	4
Carbonic anhydrase 4	Homo sapiens (human)	Ki	13.5500	1	4
Carbonic anhydrase 7	Homo sapiens (human)	Ki	0.7950	1	2
Carbonic anhydrase 9	Homo sapiens (human)	Ki	3.1450	1	2
Carboxylic ester hydrolase	Equus caballus (horse)	IC50	0.3333	3	3
Carboxylic ester hydrolase	Rattus norvegicus (Norway rat)	IC50	14.7998	12	12
Carboxylic ester hydrolase	Equus caballus (horse)	Ki	0.0020	3	3
Casein kinase I isoform alpha	Homo sapiens (human)	IC50	0.0010	1	1
Casein kinase I isoform delta	Homo sapiens (human)	IC50	0.4147	3	3
Casein kinase I isoform epsilon	Homo sapiens (human)	IC50	1.0000	1	1
Casein kinase II subunit alpha	Homo sapiens (human)	IC50	24.1660	5	5
Casein kinase II subunit alpha 3	Homo sapiens (human)	IC50	5.2550	2	2
Casein kinase II subunit alpha'	Homo sapiens (human)	IC50	24.1660	5	5
Casein kinase II subunit beta	Homo sapiens (human)	IC50	24.1660	5	5
Caspase-1	Homo sapiens (human)	IC50	6.1795	2	2
caspase-3 isoform a preproprotein	Homo sapiens (human)	IC50	17.0000	1	1
caspase-9 isoform alpha precursor	Homo sapiens (human)	IC50	17.0000	1	1
Cationic trypsin	Bos taurus (cattle)	IC50	110.8000	1	1
CDGSH iron-sulfur domain-containing protein 1	Homo sapiens (human)	IC50	2.3600	1	1
CDGSH iron-sulfur domain-containing protein 1	Homo sapiens (human)	Ki	0.1010	1	1
Cell division control protein 42 homolog	Homo sapiens (human)	IC50	6.5000	2	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	IC50	0.3285	4	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	Ki	12.0000	1	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	IC50	0.4367	3	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	Ki	12.0000	1	1
cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	IC50	11.4760	1	1
Chain A, Acetylcholinesterase	Tetronarce californica (Pacific electric ray)	Ki	0.2500	1	1
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	Bos taurus (cattle)	IC50	2.2800	1	5
Chain A, Erk2	Homo sapiens (human)	Ki	0.0004	1	1
Chain A, Exotoxin A	Pseudomonas aeruginosa	Ki	0.1400	1	1
Chain A, NAD-dependent deacetylase	Thermotoga maritima	IC50	1,000.0000	1	1
Chain A, POLYMERASE PA	Influenza A virus	IC50	1.9000	1	1
Chain A, Polymerase Pa	Influenza A virus (A/California/04/2009(H1N1))	IC50	1.9000	1	4
Chain A, Rho-associated protein kinase 1	Homo sapiens (human)	Ki	0.5300	1	3
Chain B, Rho-associated protein kinase 1	Homo sapiens (human)	Ki	0.5300	1	1
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit	Mus musculus (house mouse)	Ki	0.5300	1	1
Chain E, Fibrin beta chain	Homo sapiens (human)	IC50	46.2655	2	2
Chain I, cAMP-dependent protein kinase inhibitor alpha	synthetic construct	IC50	2.2800	1	2
Chain I, cAMP-dependent protein kinase inhibitor, alpha form	synthetic construct	Ki	0.5300	1	1
Cholecystokinin receptor type A	Homo sapiens (human)	Ki	0.3020	1	1
Cholesteryl ester transfer protein	Homo sapiens (human)	IC50	0.0400	1	1
Cholinesterase	Canis lupus familiaris (dog)	IC50	5,003.1350	1	2
Cholinesterase	Equus caballus (horse)	IC50	14.3796	30	31
Cholinesterase	Homo sapiens (human)	IC50	193.2368	49	53
Cholinesterase	Mus musculus (house mouse)	IC50	0.5557	3	3
Cholinesterase	Equus caballus (horse)	Ki	0.0020	1	1
Cholinesterase	Homo sapiens (human)	Ki	0.0002	1	1
Citron Rho-interacting kinase	Homo sapiens (human)	IC50	1.0000	1	1
Class A sortase SrtA	Staphylococcus aureus	IC50	20.0560	5	5
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	Homo sapiens (human)	IC50	7.2833	1	6
Coagulation factor VII	Homo sapiens (human)	Ki	8,000.0000	1	1
Cocaine esterase	Homo sapiens (human)	Ki	7,900.0000	1	1
Collagenase 3	Homo sapiens (human)	IC50	0.0036	3	3
Complex I intermediate-associated protein 30, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
Corticotropin-releasing factor receptor 2	Homo sapiens (human)	Ki	5.0000	1	1
COUP transcription factor 2 isoform a	Homo sapiens (human)	IC50	1.3150	1	1
CPG DNA methylase	Spiroplasma monobiae	Ki	0.0280	1	1
CREB-binding protein	Homo sapiens (human)	IC50	33.3333	6	6
Cruzipain	Trypanosoma cruzi	IC50	89.5000	2	4
Cyclin-A1	Homo sapiens (human)	IC50	15.1900	2	2
Cyclin-A2	Homo sapiens (human)	IC50	13.4600	3	3
Cyclin-dependent kinase 1	Homo sapiens (human)	IC50	60.7514	4	7
Cyclin-dependent kinase 2	Homo sapiens (human)	IC50	42.5950	4	4
Cyclin-dependent kinase 5 activator 1	Homo sapiens (human)	IC50	13.4700	3	3
Cyclin-dependent kinase 7	Homo sapiens (human)	IC50	10.0000	1	1
Cyclin-dependent kinase 9	Homo sapiens (human)	IC50	14.0000	2	2
Cyclin-dependent-like kinase 5	Homo sapiens (human)	IC50	13.4700	3	3
Cyclin-G-associated kinase	Homo sapiens (human)	IC50	0.4133	3	3
Cyclin-H	Homo sapiens (human)	IC50	10.0000	1	1
Cyclin-T1	Homo sapiens (human)	IC50	14.0000	2	2
Cysteine protease	Trypanosoma brucei rhodesiense	IC50	7.7500	1	1
Cytochrome c oxidase subunit NDUFA4	Homo sapiens (human)	IC50	14.5000	2	2
Cytochrome P450 1A1	Homo sapiens (human)	IC50	7.9060	1	1
Cytochrome P450 1A1	Homo sapiens (human)	Ki	0.5700	1	2
Cytochrome P450 1A2	Homo sapiens (human)	IC50	1.7455	2	2
Cytochrome P450 1B1	Homo sapiens (human)	IC50	1.6790	1	1
Cytochrome P450 1B1	Homo sapiens (human)	Ki	0.9100	1	1
Cytochrome P450 2A6	Homo sapiens (human)	Ki	9,150.0000	1	1
Cytochrome P450 2C19	Homo sapiens (human)	IC50	0.4027	2	2
Cytochrome P450 2C19	Homo sapiens (human)	Ki	0.0020	1	1
Cytochrome P450 2C8	Homo sapiens (human)	IC50	0.1400	1	1
Cytochrome P450 2C9	Homo sapiens (human)	IC50	4.1254	2	3
Cytochrome P450 2D6	Homo sapiens (human)	IC50	2.0000	1	1
Cytochrome P450 3A4	Homo sapiens (human)	IC50	0.0527	4	5
Cytochrome P450 3A5	Homo sapiens (human)	IC50	40.0000	1	1
D-amino-acid oxidase	Sus scrofa (pig)	IC50	1.0700	2	2
Death-associated protein kinase 1	Homo sapiens (human)	IC50	54.2000	2	3
Dehydrogenase/reductase SDR family member 9	Homo sapiens (human)	IC50	1,000.0000	1	1
Delta-type opioid receptor	Mus musculus (house mouse)	IC50	18.0087	3	3
Delta-type opioid receptor	Homo sapiens (human)	Ki	26.0000	1	1
Diacylglycerol lipase-alpha	Homo sapiens (human)	IC50	63.6500	1	2
Dihydrolipoyl dehydrogenase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	1,000.0000	1	1
Dihydrolipoyl dehydrogenase, mitochondrial	Sus scrofa (pig)	IC50	1,000.0000	1	1
Dipeptidyl peptidase 3	Homo sapiens (human)	IC50	85.0000	1	1
Dipeptidyl peptidase 4	Homo sapiens (human)	IC50	117.6050	2	2
Disintegrin and metalloproteinase domain-containing protein 10	Homo sapiens (human)	IC50	0.1356	2	2
Disintegrin and metalloproteinase domain-containing protein 12	Homo sapiens (human)	IC50	0.0059	1	1
Disintegrin and metalloproteinase domain-containing protein 17	Homo sapiens (human)	IC50	5.3344	4	4
Disintegrin and metalloproteinase domain-containing protein 9	Homo sapiens (human)	IC50	0.0286	2	2
DNA (cytosine-5)-methyltransferase 1	Homo sapiens (human)	IC50	0.5000	1	1
DNA gyrase subunit A	Mycobacterium tuberculosis H37Rv	IC50	50.0000	1	1
DNA gyrase subunit B	Mycobacterium tuberculosis H37Rv	IC50	50.0000	1	1
DNA repair protein RAD52 homolog	Homo sapiens (human)	IC50	2.5108	5	5
DNA topoisomerase 1	Homo sapiens (human)	IC50	250.0000	1	4
DNA topoisomerase 2-alpha	Homo sapiens (human)	IC50	250.0000	1	4
DNA-3-methyladenine glycosylase	Homo sapiens (human)	IC50	2.6000	1	1
DNA-dependent protein kinase catalytic subunit	Homo sapiens (human)	IC50	50.0000	1	1
DNA-directed RNA polymerase subunit beta	Escherichia coli O127:H6 str. E2348/69	IC50	511.3333	3	3
DNA-directed RNA polymerase subunit beta	Mycobacterium tuberculosis H37Rv	IC50	0.0100	1	1
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	IC50	61.0000	1	1
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	IC50	61.0000	1	1
Dual specificity protein kinase CLK1	Homo sapiens (human)	IC50	0.0710	1	1
Dual specificity protein kinase CLK1	Mus musculus (house mouse)	IC50	0.0360	4	4
Dual specificity protein kinase CLK2	Mus musculus (house mouse)	IC50	0.3900	3	3
Dual specificity protein kinase CLK3	Mus musculus (house mouse)	IC50	6.0500	4	4
Dual specificity protein kinase CLK4	Mus musculus (house mouse)	IC50	0.0393	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	IC50	1.3531	11	11
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Rattus norvegicus (Norway rat)	IC50	0.1050	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	IC50	0.0550	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	IC50	0.0855	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 3	Homo sapiens (human)	IC50	0.4167	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 4	Homo sapiens (human)	IC50	0.5200	1	1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	Homo sapiens (human)	IC50	10.3000	1	1
Endothelial PAS domain-containing protein 1	Homo sapiens (human)	IC50	0.0360	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	Mycobacterium tuberculosis H37Rv	IC50	0.0300	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	Escherichia coli K-12	IC50	10.0000	2	2
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	1.8167	2	3
Enoyl-acyl-carrier protein reductase	Plasmodium falciparum (malaria parasite P. falciparum)	Ki	0.0910	3	3
Ephrin type-B receptor 2	Homo sapiens (human)	IC50	7.8000	1	1
Ephrin type-B receptor 4	Homo sapiens (human)	IC50	50.0000	1	1
Epidermal growth factor receptor	Homo sapiens (human)	IC50	61.2223	18	20
Estrogen receptor	Homo sapiens (human)	IC50	7.9120	1	1
Estrogen receptor	Homo sapiens (human)	Ki	2.2600	1	1
estrogen receptor beta isoform 1	Homo sapiens (human)	IC50	2.9272	1	2
Eukaryotic initiation factor 4A-I	Homo sapiens (human)	IC50	0.1390	4	4
eukaryotic translation initiation factor 4 gamma 1 isoform 4	Homo sapiens (human)	IC50	1.1500	1	1
eukaryotic translation initiation factor 4E isoform 1	Mus musculus (house mouse)	IC50	1.1500	1	1
Fatty acid synthase	Gallus gallus (chicken)	IC50	68.0000	3	3
Fatty acid synthase	Homo sapiens (human)	IC50	51.9700	1	1
Fatty-acid amide hydrolase 1	Homo sapiens (human)	IC50	250.4500	2	2
Fatty-acid amide hydrolase 1	Rattus norvegicus (Norway rat)	IC50	4.1559	2	2
Fatty-acid amide hydrolase 1	Rattus norvegicus (Norway rat)	Ki	0.0269	1	1
Fibroblast growth factor receptor 1	Homo sapiens (human)	IC50	4.5190	4	6
Focal adhesion kinase 1	Homo sapiens (human)	IC50	1.6000	1	1
G protein-coupled receptor kinase 5	Homo sapiens (human)	IC50	0.8300	1	1
G-protein coupled receptor 35	Homo sapiens (human)	IC50	20.3000	2	2
G-protein coupled receptor 35	Homo sapiens (human)	Ki	137.0000	1	1
G2/mitotic-specific cyclin-B1	Homo sapiens (human)	IC50	60.7514	4	7
G2/mitotic-specific cyclin-B2	Homo sapiens (human)	IC50	36.9667	2	3
G2/mitotic-specific cyclin-B3	Homo sapiens (human)	IC50	36.9667	2	3
GABA theta subunit	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit alpha-1	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit alpha-1	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit alpha-2	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Ki	35.2184	3	4
Gamma-aminobutyric acid receptor subunit alpha-3	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit alpha-3	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit alpha-4	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit alpha-4	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit alpha-5	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit alpha-5	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit alpha-5	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit alpha-6	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit alpha-6	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit alpha-6	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit beta-1	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit beta-1	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit beta-1	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit beta-2	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit beta-2	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit beta-2	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit beta-3	Homo sapiens (human)	IC50	1,453.0000	2	2
Gamma-aminobutyric acid receptor subunit beta-3	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit beta-3	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit delta	Homo sapiens (human)	IC50	6.0000	1	1
Gamma-aminobutyric acid receptor subunit delta	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit delta	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit epsilon	Homo sapiens (human)	IC50	6.0000	1	1
Gamma-aminobutyric acid receptor subunit epsilon	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit epsilon	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit gamma-1	Homo sapiens (human)	IC50	6.0000	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit gamma-2	Homo sapiens (human)	IC50	6.0000	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit gamma-2	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit gamma-3	Homo sapiens (human)	IC50	6.0000	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit pi	Homo sapiens (human)	IC50	6.0000	1	1
Gamma-aminobutyric acid receptor subunit pi	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-aminobutyric acid receptor subunit pi	Rattus norvegicus (Norway rat)	Ki	33.3355	2	3
Gamma-aminobutyric acid receptor subunit theta	Homo sapiens (human)	IC50	6.0000	1	1
Gamma-aminobutyric acid receptor subunit theta	Homo sapiens (human)	Ki	77.6247	1	1
Gamma-butyrobetaine dioxygenase	Homo sapiens (human)	IC50	10.9517	6	6
Gamma-butyrobetaine dioxygenase	Homo sapiens (human)	Ki	16.0000	1	1
Gastrin/cholecystokinin type B receptor	Homo sapiens (human)	Ki	0.3020	1	1
Genome polyprotein	Zika virus	IC50	87.0000	1	1
Glucagon-like peptide 1 receptor	Homo sapiens (human)	IC50	0.0024	2	2
Glucagon-like peptide 1 receptor	Homo sapiens (human)	Ki	0.0054	2	2
Glucocorticoid receptor	Homo sapiens (human)	IC50	0.0110	1	1
Glucocorticoid receptor	Homo sapiens (human)	Ki	0.0050	1	1
Glucose transporter	Leishmania mexicana	IC50	0.2420	1	1
Glucose-6-phosphate 1-dehydrogenase	Saccharomyces cerevisiae S288C	IC50	0.2500	1	1
glucose-6-phosphate 1-dehydrogenase isoform b	Homo sapiens (human)	IC50	13.2000	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	Plasmodium berghei	IC50	15.0867	3	3
Glutamate receptor 1	Rattus norvegicus (Norway rat)	IC50	118.0000	2	3
Glutamate receptor 2	Rattus norvegicus (Norway rat)	IC50	118.0000	2	3
Glutamate receptor 3	Rattus norvegicus (Norway rat)	IC50	118.0000	2	3
Glutamate receptor 4	Rattus norvegicus (Norway rat)	IC50	118.0000	2	3
Glutamate receptor ionotropic, kainate 1	Rattus norvegicus (Norway rat)	IC50	820.0000	2	5
Glutamate receptor ionotropic, kainate 2	Rattus norvegicus (Norway rat)	IC50	820.0000	2	5
Glutamate receptor ionotropic, kainate 3	Rattus norvegicus (Norway rat)	IC50	820.0000	2	5
Glutamate receptor ionotropic, kainate 4	Rattus norvegicus (Norway rat)	IC50	820.0000	2	5
Glutamate receptor ionotropic, kainate 5	Rattus norvegicus (Norway rat)	IC50	820.0000	2	5
Glutamate receptor ionotropic, NMDA 1	Homo sapiens (human)	IC50	3.5675	17	17
Glutamate receptor ionotropic, NMDA 1	Homo sapiens (human)	Ki	0.2637	6	8
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	IC50	29.4422	31	37
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	Ki	0.5349	8	12
Glutamate receptor ionotropic, NMDA 2A	Homo sapiens (human)	IC50	7.6094	12	12
Glutamate receptor ionotropic, NMDA 2A	Homo sapiens (human)	Ki	0.1833	4	6
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	IC50	33.7748	26	31
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	Ki	0.0926	7	11
Glutamate receptor ionotropic, NMDA 2B	Homo sapiens (human)	IC50	3.0328	12	12
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	IC50	28.4272	29	35
Glutamate receptor ionotropic, NMDA 2B	Homo sapiens (human)	Ki	0.2536	7	9
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	Ki	0.0926	7	11
Glutamate receptor ionotropic, NMDA 2C	Homo sapiens (human)	IC50	5.0040	3	3
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	IC50	35.4515	23	28
Glutamate receptor ionotropic, NMDA 2C	Homo sapiens (human)	Ki	0.1833	4	6
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	Ki	0.1432	7	12
Glutamate receptor ionotropic, NMDA 2D	Homo sapiens (human)	IC50	5.0040	3	3
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	IC50	35.4515	23	28
Glutamate receptor ionotropic, NMDA 2D	Homo sapiens (human)	Ki	0.1833	4	6
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	Ki	0.0926	7	11
Glutamate receptor ionotropic, NMDA 3A	Homo sapiens (human)	IC50	5.0040	3	3
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	IC50	35.4515	23	28
Glutamate receptor ionotropic, NMDA 3A	Homo sapiens (human)	Ki	0.1833	4	6
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	Ki	0.0926	7	11
Glutamate receptor ionotropic, NMDA 3B	Homo sapiens (human)	IC50	5.0040	3	3
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	IC50	35.4515	23	28
Glutamate receptor ionotropic, NMDA 3B	Homo sapiens (human)	Ki	0.1833	4	6
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	Ki	0.0926	7	11
Glutathione reductase	Plasmodium falciparum 3D7	IC50	6.4000	1	1
Glutathione reductase, mitochondrial	Homo sapiens (human)	IC50	16.2000	2	2
Glutathione S-transferase omega-1	Homo sapiens (human)	IC50	75.0000	1	1
Glutathione S-transferase P	Homo sapiens (human)	IC50	69.0000	1	1
Glycine receptor subunit alpha-1	Rattus norvegicus (Norway rat)	IC50	0.0110	1	1
Glycine receptor subunit alpha-1	Rattus norvegicus (Norway rat)	Ki	0.0050	1	1
Glycine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	IC50	0.0110	1	1
Glycine receptor subunit alpha-2	Rattus norvegicus (Norway rat)	Ki	0.0050	1	1
Glycine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	IC50	0.0110	1	1
Glycine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	Ki	0.0050	1	1
Glycine receptor subunit beta	Rattus norvegicus (Norway rat)	IC50	0.0110	1	1
Glycine receptor subunit beta	Rattus norvegicus (Norway rat)	Ki	0.0050	1	1
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	IC50	1.5870	5	6
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Ki	0.0308	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	IC50	4.4879	31	36
Glycogen synthase kinase-3 beta	Rattus norvegicus (Norway rat)	IC50	0.0660	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Ki	0.0240	1	1
Glycogen synthase kinase-3 beta	Sus scrofa (pig)	IC50	2.9350	4	4
Heat shock protein HSP 90-beta	Homo sapiens (human)	IC50	155.0000	1	1
Heme oxygenase 1	Rattus norvegicus (Norway rat)	IC50	14.0000	2	2
Heme oxygenase 2	Rattus norvegicus (Norway rat)	IC50	14.0000	2	2
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	7.4287	7	7
Hepatocyte growth factor receptor	Homo sapiens (human)	Ki	3.3000	1	1
hexokinase	Trypanosoma brucei brucei TREU927	IC50	0.9009	1	1
Hexose transporter 1	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	0.3100	1	1
high affinity choline transporter 1 isoform a	Homo sapiens (human)	IC50	1.8613	2	2
Histone acetyltransferase KAT2B	Homo sapiens (human)	IC50	32.9667	6	6
Histone acetyltransferase KAT5	Homo sapiens (human)	IC50	68.0000	3	3
Histone acetyltransferase KAT8	Homo sapiens (human)	IC50	43.0000	1	1
Histone acetyltransferase KAT8	Homo sapiens (human)	Ki	64.0000	1	1
Histone acetyltransferase p300	Homo sapiens (human)	IC50	18.4292	11	12
Histone deacetylase 1	Homo sapiens (human)	IC50	1,020.8011	8	9
Histone deacetylase 1	Homo sapiens (human)	Ki	207.0433	2	3
Histone deacetylase 11	Homo sapiens (human)	IC50	2,807.3333	3	3
Histone deacetylase 11	Homo sapiens (human)	Ki	285.1700	1	2
Histone deacetylase 2	Homo sapiens (human)	IC50	1,547.7900	6	6
Histone deacetylase 2	Homo sapiens (human)	Ki	222.6700	2	3
Histone deacetylase 3	Homo sapiens (human)	IC50	1,569.6117	6	6
Histone deacetylase 3	Homo sapiens (human)	Ki	285.1700	1	2
Histone deacetylase 4	Homo sapiens (human)	IC50	2,284.4000	5	5
Histone deacetylase 4	Homo sapiens (human)	Ki	285.1700	1	2
Histone deacetylase 5	Homo sapiens (human)	IC50	1,904.2333	6	6
Histone deacetylase 5	Homo sapiens (human)	Ki	285.1700	1	2
Histone deacetylase 6	Homo sapiens (human)	IC50	1,295.1789	9	9
Histone deacetylase 6	Homo sapiens (human)	Ki	285.1700	1	2
Histone deacetylase 7	Homo sapiens (human)	IC50	2,605.5000	4	4
Histone deacetylase 7	Homo sapiens (human)	Ki	285.1700	1	2
Histone deacetylase 8	Homo sapiens (human)	IC50	1,741.8600	5	5
Histone deacetylase 8	Homo sapiens (human)	Ki	211.7733	2	3
Histone deacetylase 9	Homo sapiens (human)	IC50	2,085.1400	5	5
Histone deacetylase 9	Homo sapiens (human)	Ki	285.1700	1	2
Histone-lysine N-methyltransferase EHMT1	Homo sapiens (human)	IC50	0.7300	1	1
Histone-lysine N-methyltransferase EHMT2	Homo sapiens (human)	IC50	0.4000	1	1
Histone-lysine N-methyltransferase SETD7	Homo sapiens (human)	IC50	6.0200	1	1
hypothetical protein SA1422	Staphylococcus aureus subsp. aureus N315	IC50	42.9000	2	2
Hypoxia-inducible factor 1-alpha	Homo sapiens (human)	IC50	0.0360	1	1
Ileal sodium/bile acid cotransporter	Homo sapiens (human)	Ki	28.0000	1	1
Indoleamine 2,3-dioxygenase 1	Homo sapiens (human)	Ki	0.0940	3	3
Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens (human)	IC50	0.9200	1	1
Inhibin alpha chain	Homo sapiens (human)	IC50	5.2000	1	1
Insulin receptor	Homo sapiens (human)	IC50	3.2000	1	1
Insulin-degrading enzyme	Homo sapiens (human)	IC50	33.3520	3	3
Integrase	Human immunodeficiency virus 1	IC50	29.1179	10	10
integrase, partial	Human immunodeficiency virus 1	IC50	17.9040	2	4
Interstitial collagenase	Homo sapiens (human)	IC50	0.4064	12	12
Interstitial collagenase	Homo sapiens (human)	Ki	0.0004	1	1
intestinal alkaline phosphatase precursor	Mus musculus (house mouse)	IC50	18.7000	1	1
Islet amyloid polypeptide	Homo sapiens (human)	IC50	7.8000	1	1
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)	IC50	168.3452	3	6
L-lactate dehydrogenase A chain	Homo sapiens (human)	Ki	6.5000	1	1
Lactoylglutathione lyase	Homo sapiens (human)	Ki	15.1022	2	2
Lanosterol 14-alpha demethylase	Homo sapiens (human)	IC50	30.0000	1	1
large T antigen	Betapolyomavirus macacae	IC50	34.6700	1	2
lens epithelium-derived growth factor p75	Homo sapiens (human)	IC50	17.9040	2	4
Lethal factor	Bacillus anthracis	IC50	0.0970	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	0.0215	2	2
Liver carboxylesterase 1	Homo sapiens (human)	Ki	363.0000	1	1
Low molecular weight phosphotyrosine protein phosphatase	Bos taurus (cattle)	IC50	10.0000	1	1
Lysine-specific histone demethylase 1A	Homo sapiens (human)	IC50	3.2317	6	6
Lysosomal Pro-X carboxypeptidase	Homo sapiens (human)	IC50	0.0126	1	2
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	IC50	0.0888	4	4
Macrophage metalloelastase	Homo sapiens (human)	IC50	0.0057	7	7
Macrophage migration inhibitory factor	Homo sapiens (human)	IC50	2.4000	1	1
Macrophage migration inhibitory factor	Homo sapiens (human)	Ki	0.5700	2	2
MAP kinase-activated protein kinase 5	Homo sapiens (human)	IC50	1.0000	1	1
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	GI50	0.1986	53	53
Mast/stem cell growth factor receptor Kit	Mus musculus (house mouse)	GI50	0.0030	1	1
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	IC50	0.2639	18	18
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Ki	0.0040	1	1
Matrilysin	Homo sapiens (human)	IC50	7.2487	4	9
Matrix metalloproteinase-14	Homo sapiens (human)	IC50	0.6275	11	11
Matrix metalloproteinase-15	Homo sapiens (human)	IC50	0.0060	2	2
Matrix metalloproteinase-16	Homo sapiens (human)	IC50	0.0080	2	2
Matrix metalloproteinase-17	Homo sapiens (human)	IC50	0.0034	1	1
Matrix metalloproteinase-26	Homo sapiens (human)	IC50	0.0170	2	2
Matrix metalloproteinase-9	Homo sapiens (human)	IC50	0.0034	12	12
Matrix metalloproteinase-9	Homo sapiens (human)	Ki	0.0004	2	2
Mcl-1	Homo sapiens (human)	IC50	2.9883	1	1
Melatonin receptor type 1A	Homo sapiens (human)	Ki	1.9000	1	1
Metabotropic glutamate receptor 1	Homo sapiens (human)	Ki	100.0000	1	1
Metabotropic glutamate receptor 2	Homo sapiens (human)	Ki	0.4135	3	5
Metabotropic glutamate receptor 3	Homo sapiens (human)	Ki	0.2141	3	5
Metabotropic glutamate receptor 4	Homo sapiens (human)	Ki	21.0000	1	1
Metabotropic glutamate receptor 5	Homo sapiens (human)	Ki	100.0000	1	1
Metabotropic glutamate receptor 6	Homo sapiens (human)	Ki	0.4000	1	1
Metabotropic glutamate receptor 7	Homo sapiens (human)	Ki	100.0000	1	1
Metabotropic glutamate receptor 8	Homo sapiens (human)	Ki	1.7000	1	1
Methionine aminopeptidase 2	Homo sapiens (human)	IC50	2.4300	1	1
microphthalmia-associated transcription factor isoform 9	Homo sapiens (human)	IC50	6.3810	3	3
Microtubule-associated protein tau	Homo sapiens (human)	IC50	28.7778	7	9
Mitogen-activated protein kinase 1	Homo sapiens (human)	IC50	0.6860	1	1
Mitogen-activated protein kinase 1	Rattus norvegicus (Norway rat)	IC50	343.3493	2	3
Mitogen-activated protein kinase 10	Homo sapiens (human)	IC50	8.0560	4	5
Mitogen-activated protein kinase 10	Homo sapiens (human)	Ki	0.0900	1	1
Mitogen-activated protein kinase 11	Homo sapiens (human)	IC50	0.2646	26	27
Mitogen-activated protein kinase 11	Homo sapiens (human)	Ki	1,300.0000	1	1
Mitogen-activated protein kinase 12	Homo sapiens (human)	IC50	0.2329	21	22
Mitogen-activated protein kinase 12	Homo sapiens (human)	Ki	1,300.0000	1	1
Mitogen-activated protein kinase 13	Homo sapiens (human)	IC50	0.2329	21	22
Mitogen-activated protein kinase 13	Homo sapiens (human)	Ki	1,300.0000	1	1
Mitogen-activated protein kinase 14	Homo sapiens (human)	IC50	15.2565	75	79
Mitogen-activated protein kinase 14	Homo sapiens (human)	Ki	433.3583	3	3
Mitogen-activated protein kinase 14	Mus musculus (house mouse)	IC50	0.0560	1	3
Mitogen-activated protein kinase 2	Pneumocystis carinii	IC50	0.1050	1	1
Mitogen-activated protein kinase 9	Homo sapiens (human)	IC50	2.3871	7	7
MO15-related protein kinase Pfmrk	Plasmodium falciparum (malaria parasite P. falciparum)	IC50	500.0000	1	1
MPI protein	Homo sapiens (human)	IC50	0.2905	2	2
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)	IC50	0.0180	1	1
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	Ki	100.0000	1	1
Multidrug resistance-associated protein 4	Homo sapiens (human)	IC50	33.1567	1	3
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	IC50	10.6660	1	1
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	Ki	2.5690	1	1
Muscarinic acetylcholine receptor M1	Rattus norvegicus (Norway rat)	Ki	100.0000	1	1
Muscarinic acetylcholine receptor M2	Rattus norvegicus (Norway rat)	Ki	100.0000	1	1
Muscarinic acetylcholine receptor M3	Rattus norvegicus (Norway rat)	Ki	100.0000	1	1
Muscarinic acetylcholine receptor M4	Rattus norvegicus (Norway rat)	Ki	100.0000	1	1
Muscarinic acetylcholine receptor M5	Homo sapiens (human)	IC50	0.0020	1	1
Muscarinic acetylcholine receptor M5	Rattus norvegicus (Norway rat)	Ki	100.0000	1	1
Myeloperoxidase	Homo sapiens (human)	Ki	0.0460	2	2
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	IC50	12.6000	2	2
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Ki	36.0000	1	1
Myotonin-protein kinase	Homo sapiens (human)	IC50	4.5000	2	2
N-acylethanolamine-hydrolyzing acid amidase	Homo sapiens (human)	IC50	75.0000	1	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	Homo sapiens (human)	Ki	0.0500	1	1
NACHT, LRR and PYD domains-containing protein 3	Homo sapiens (human)	IC50	24.2000	1	1
NACHT, LRR and PYD domains-containing protein 3	Mus musculus (house mouse)	IC50	10.0000	1	1
NAD kinase	Homo sapiens (human)	IC50	0.9600	1	1
NAD kinase	Homo sapiens (human)	Ki	3.2800	1	1
NAD-dependent histone deacetylase SIR2	Saccharomyces cerevisiae S288C	IC50	50.0000	1	1
NAD-dependent protein deacetylase	Schistosoma mansoni	IC50	221.5500	2	2
NAD-dependent protein deacetylase HST2	Saccharomyces cerevisiae S288C	IC50	91.0000	1	1
NAD-dependent protein deacetylase sirtuin-1	Homo sapiens (human)	IC50	130.9500	12	12
NAD-dependent protein deacetylase sirtuin-2	Homo sapiens (human)	IC50	34.5200	15	15
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	Homo sapiens (human)	IC50	78.4571	7	7
NAD-dependent protein deacetylase sirtuin-6	Homo sapiens (human)	IC50	173.3500	4	4
NAD-dependent protein deacylase sirtuin-5, mitochondrial	Homo sapiens (human)	IC50	68.6500	4	4
NAD(+) hydrolase SARM1	Homo sapiens (human)	IC50	43.8000	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] 1 subunit C2	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase chain 1	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase chain 2	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase chain 3	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase chain 4	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase chain 4L	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase chain 5	Homo sapiens (human)	IC50	14.5000	2	2
NADH-ubiquinone oxidoreductase chain 6	Homo sapiens (human)	IC50	14.5000	2	2
Neuraminidase	Influenza A virus (A/Wilson-Smith/1933(H1N1))	IC50	63.8000	1	1
Neuronal acetylcholine receptor subunit alpha-3	Rattus norvegicus (Norway rat)	IC50	6.0000	1	1
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	IC50	0.8200	1	1
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	Ki	0.0900	1	1
Neuronal acetylcholine receptor subunit alpha-6	Rattus norvegicus (Norway rat)	IC50	6.0000	1	1
Neuronal acetylcholine receptor subunit alpha-7	Homo sapiens (human)	IC50	7.0000	1	1
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	IC50	0.8200	1	1
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	Ki	0.0900	1	1
Neuronal acetylcholine receptor subunit beta-4	Rattus norvegicus (Norway rat)	IC50	6.0000	1	1
Neuronal proto-oncogene tyrosine-protein kinase Src	Mus musculus (house mouse)	IC50	2.2000	1	1
Neutrophil collagenase	Homo sapiens (human)	IC50	0.0054	2	2
Neutrophil collagenase	Homo sapiens (human)	Ki	0.0002	2	2
neutrophil cytosol factor 1	Homo sapiens (human)	IC50	0.3900	1	2
Neutrophil cytosol factor 1	Homo sapiens (human)	Ki	125.0000	3	3
Neutrophil elastase	Homo sapiens (human)	IC50	6.4125	2	2
NH(3)-dependent NAD(+) synthetase	Bacillus subtilis subsp. subtilis str. 168	IC50	1.0000	1	1
Nitric oxide synthase, brain	Homo sapiens (human)	IC50	0.0600	1	1
Nitric oxide synthase, brain	Homo sapiens (human)	Ki	0.0500	1	1
Nitric oxide synthase, brain	Rattus norvegicus (Norway rat)	IC50	0.0600	1	1
Nitric oxide synthase, brain	Rattus norvegicus (Norway rat)	Ki	0.0500	1	1
Nitric oxide synthase, endothelial	Homo sapiens (human)	IC50	0.4000	1	1
Nitric oxide synthase, endothelial	Rattus norvegicus (Norway rat)	IC50	2.9000	1	1
Nitric oxide synthase, inducible	Homo sapiens (human)	IC50	0.3000	1	1
NUAK family SNF1-like kinase 1	Homo sapiens (human)	IC50	0.0480	1	1
Nuclear factor NF-kappa-B p100 subunit	Homo sapiens (human)	IC50	35.8500	2	2
Nuclear factor NF-kappa-B p105 subunit	Homo sapiens (human)	IC50	35.8500	2	2
P2X purinoceptor 7	Homo sapiens (human)	IC50	5.0000	1	1
P2X purinoceptor 7	Rattus norvegicus (Norway rat)	IC50	30.0000	1	1
P2Y purinoceptor 12	Homo sapiens (human)	Ki	36.4000	1	1
Pancreatic triacylglycerol lipase	Sus scrofa (pig)	IC50	100.0000	1	1
Peptidyl-prolyl cis-trans isomerase FKBP14	Homo sapiens (human)	Ki	76.2000	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	Homo sapiens (human)	IC50	3.6000	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	Homo sapiens (human)	Ki	3.4000	1	1
Peptidyl-prolyl cis-trans isomerase FKBP3	Homo sapiens (human)	Ki	124.0000	1	1
Peptidyl-prolyl cis-trans isomerase FKBP4	Homo sapiens (human)	Ki	24.2000	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	IC50	20.0000	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	Ki	200.0000	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4	Homo sapiens (human)	Ki	187.0000	1	1
perilipin-1	Homo sapiens (human)	IC50	6.2885	1	2
perilipin-5	Homo sapiens (human)	IC50	5.6665	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	IC50	11.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	IC50	50.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	IC50	12.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	IC50	13.0000	1	1
phosphoethanolamine/phosphocholine phosphatase isoform 1	Homo sapiens (human)	IC50	0.1110	1	1
Phosphoglycerate mutase 1	Homo sapiens (human)	IC50	0.4900	2	2
Phospholipase A2	Homo sapiens (human)	IC50	11.1000	1	1
phosphomannomutase 2	Homo sapiens (human)	IC50	0.6720	1	1
Plasminogen activator inhibitor 1	Homo sapiens (human)	IC50	0.0910	1	1
Platelet-activating factor receptor	Cavia porcellus (domestic guinea pig)	IC50	4.5000	1	1
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	GI50	0.3305	2	2
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50	0.0610	4	4
Platelet-derived growth factor receptor alpha	Mus musculus (house mouse)	IC50	0.0186	7	7
Platelet-derived growth factor receptor beta	Homo sapiens (human)	GI50	0.1140	1	1
Platelet-derived growth factor receptor beta	Homo sapiens (human)	IC50	12.8953	22	24
Platelet-derived growth factor receptor beta	Mus musculus (house mouse)	IC50	0.0186	7	7
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Ki	0.0080	1	1
Poly [ADP-ribose] polymerase 1	Homo sapiens (human)	IC50	54.6213	17	24
Poly [ADP-ribose] polymerase 2	Homo sapiens (human)	IC50	0.1687	3	5
Poly [ADP-ribose] polymerase 2	Mus musculus (house mouse)	IC50	64.7825	1	4
Poly [ADP-ribose] polymerase tankyrase-1	Homo sapiens (human)	IC50	1.1077	4	6
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	IC50	1.2683	3	5
Polyamine deacetylase HDAC10	Homo sapiens (human)	IC50	2,807.3333	3	3
Polyamine deacetylase HDAC10	Homo sapiens (human)	Ki	285.1700	1	2
Polymerase acidic protein	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50	5.8600	1	1
Polyphenol oxidase 2	Agaricus bisporus	IC50	200.0000	1	1
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	IC50	8.9460	5	5
Polyunsaturated fatty acid 5-lipoxygenase	Homo sapiens (human)	Ki	24.2000	1	2
Polyunsaturated fatty acid lipoxygenase ALOX15	Homo sapiens (human)	IC50	12.0150	2	2
Polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus (rabbit)	IC50	2.9490	1	1
Potassium voltage-gated channel subfamily D member 3	Homo sapiens (human)	IC50	50.1187	1	1
Potassium voltage-gated channel subfamily E member 1	Homo sapiens (human)	IC50	63.0957	1	1
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	IC50	3.8389	5	5
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	Ki	25.1189	1	1
Potassium voltage-gated channel subfamily KQT member 1	Homo sapiens (human)	IC50	63.0957	1	1
Probable linoleate 9S-lipoxygenase 5	Solanum tuberosum (potato)	IC50	43.0000	1	1
Procathepsin L	Homo sapiens (human)	IC50	1.1100	1	2
Programmed cell death 1 ligand 1	Homo sapiens (human)	IC50	100.0000	1	1
Programmed cell death protein 1	Homo sapiens (human)	IC50	100.0000	1	1
Prolyl endopeptidase	Homo sapiens (human)	IC50	12.1500	2	2
Prolyl endopeptidase	Sus scrofa (pig)	IC50	0.0060	1	1
Prostaglandin E synthase	Homo sapiens (human)	IC50	1.8000	3	4
Prostaglandin G/H synthase 1	Homo sapiens (human)	IC50	20,021.7403	7	9
Prostaglandin G/H synthase 1	Ovis aries (sheep)	IC50	63.8350	1	2
Prostaglandin G/H synthase 1	Bos taurus (cattle)	IC50	1.0503	2	2
Prostaglandin G/H synthase 2	Homo sapiens (human)	IC50	15,027.9675	6	8
Prostaglandin G/H synthase 2	Ovis aries (sheep)	IC50	11.3000	1	1
Prostaglandin G/H synthase 2	Bos taurus (cattle)	IC50	0.0006	1	1
Proteasome subunit beta type-5	Homo sapiens (human)	IC50	7.8172	5	5
Protein delta homolog 1	Homo sapiens (human)	Ki	0.0063	1	1
Protein E6	Human papillomavirus 16	IC50	4.0000	1	1
Protein kinase C alpha type	Homo sapiens (human)	IC50	42.1500	2	2
Protein kinase C alpha type	Rattus norvegicus (Norway rat)	IC50	36.5170	4	4
Protein kinase C alpha type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein kinase C beta type	Homo sapiens (human)	IC50	75.0000	1	1
Protein kinase C beta type	Rattus norvegicus (Norway rat)	IC50	49.2136	5	5
Protein kinase C beta type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein kinase C delta type	Homo sapiens (human)	IC50	75.0000	1	1
Protein kinase C delta type	Rattus norvegicus (Norway rat)	IC50	36.5170	4	4
Protein kinase C delta type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein kinase C epsilon type	Homo sapiens (human)	IC50	27.0000	3	3
Protein kinase C epsilon type	Rattus norvegicus (Norway rat)	IC50	36.5170	4	4
Protein kinase C epsilon type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein kinase C eta type	Homo sapiens (human)	IC50	75.0000	1	1
Protein kinase C eta type	Rattus norvegicus (Norway rat)	IC50	36.5170	4	4
Protein kinase C eta type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein kinase C gamma type	Homo sapiens (human)	IC50	75.0000	1	1
Protein kinase C gamma type	Rattus norvegicus (Norway rat)	IC50	36.5170	4	4
Protein kinase C gamma type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein kinase C iota type	Homo sapiens (human)	IC50	75.0000	1	1
Protein kinase C theta type	Homo sapiens (human)	IC50	75.0000	1	1
Protein kinase C theta type	Rattus norvegicus (Norway rat)	IC50	36.5170	4	4
Protein kinase C theta type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein kinase C zeta type	Homo sapiens (human)	IC50	75.0000	1	1
Protein kinase C zeta type	Rattus norvegicus (Norway rat)	IC50	36.5170	4	4
Protein kinase C zeta type	Rattus norvegicus (Norway rat)	Ki	25.0000	2	2
Protein mono-ADP-ribosyltransferase PARP10	Homo sapiens (human)	IC50	6.3123	2	4
Protein mono-ADP-ribosyltransferase PARP12	Homo sapiens (human)	IC50	0.2269	1	2
Protein mono-ADP-ribosyltransferase PARP14	Homo sapiens (human)	IC50	4.1843	1	2
Protein mono-ADP-ribosyltransferase PARP15	Homo sapiens (human)	IC50	10.9708	2	3
Protein mono-ADP-ribosyltransferase PARP3	Homo sapiens (human)	IC50	1.4377	1	2
Protein mono-ADP-ribosyltransferase PARP4	Homo sapiens (human)	IC50	0.7586	1	1
Prothrombin	Homo sapiens (human)	IC50	0.2500	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	IC50	0.3500	5	5
Proto-oncogene tyrosine-protein kinase Src	Gallus gallus (chicken)	IC50	0.5550	1	1
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50	1.8509	3	3
Proton-coupled amino acid transporter 1	Homo sapiens (human)	Ki	24,600.0000	1	2
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	IC50	10.0000	1	1
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	IC50	2.6060	5	5
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	IC50	10.1125	1	2
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	IC50	1.0359	7	8
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50	0.1042	27	27
Receptor-type tyrosine-protein phosphatase S	Homo sapiens (human)	IC50	4.3000	1	1
Renin	Homo sapiens (human)	Ki	0.0006	1	1
Replicase polyprotein 1a	Severe acute respiratory syndrome-related coronavirus	IC50	1.1100	1	2
Replicase polyprotein 1ab	Betacoronavirus England 1	IC50	7.4600	2	7
Replicase polyprotein 1ab	Human coronavirus 229E	IC50	1.1100	1	2
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	IC50	3.8727	20	38
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	IC50	8.5578	2	9
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	IC50	31.3650	2	2
Rho-associated protein kinase 1	Homo sapiens (human)	IC50	1.0502	10	10
Rho-associated protein kinase 1	Homo sapiens (human)	Ki	0.4300	6	7
Rho-associated protein kinase 2	Bos taurus (cattle)	IC50	1.8042	1	12
Rho-associated protein kinase 2	Homo sapiens (human)	IC50	1.3060	14	14
Rho-associated protein kinase 2	Rattus norvegicus (Norway rat)	IC50	1.9000	1	1
Rho-associated protein kinase 2	Homo sapiens (human)	Ki	0.3300	1	1
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	IC50	0.1313	1	1
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	IC50	0.1839	1	1
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	IC50	5.0000	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	IC50	5.1000	1	1
RNA polymerase beta subunit (EC 2.7.7.6), partial	Escherichia coli	IC50	11.6872	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)	IC50	7.5000	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)	Ki	5.8000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	Homo sapiens (human)	IC50	7.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	Homo sapiens (human)	Ki	53.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	Rattus norvegicus (Norway rat)	Ki	5.8000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	Homo sapiens (human)	IC50	7.0000	1	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	Homo sapiens (human)	Ki	8.6000	1	1
Seed linoleate 13S-lipoxygenase-1	Glycine max (soybean)	IC50	51.9000	1	1
Serine/threonine-protein kinase 36	Homo sapiens (human)	IC50	1.0000	1	1
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	IC50	1.0000	1	1
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	IC50	0.0773	1	1
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	IC50	0.0168	1	1
Serine/threonine-protein kinase D1	Homo sapiens (human)	IC50	75.0000	1	1
Serine/threonine-protein kinase D3	Homo sapiens (human)	IC50	75.0000	1	1
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	IC50	50.0000	1	1
Serine/threonine-protein kinase N1	Homo sapiens (human)	IC50	1.7000	1	1
Serine/threonine-protein kinase N2	Homo sapiens (human)	IC50	1.8533	3	3
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	IC50	12.0000	1	1
Serine/threonine-protein kinase NLK	Homo sapiens (human)	IC50	1.0000	1	1
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	IC50	16.0000	1	1
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	IC50	0.5692	2	2
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Ki	0.5000	1	1
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	IC50	37.1467	5	6
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	IC50	8.7367	3	3
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Ki	12.4000	1	4
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	IC50	0.2200	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	IC50	1.3000	1	1
Sigma non-opioid intracellular receptor 1	Cavia porcellus (domestic guinea pig)	IC50	10.0000	1	1
Sigma non-opioid intracellular receptor 1	Rattus norvegicus (Norway rat)	IC50	0.9700	1	2
Sigma non-opioid intracellular receptor 1	Cavia porcellus (domestic guinea pig)	Ki	10.0000	1	1
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	Ki	59.1670	1	2
Sigma non-opioid intracellular receptor 1	Rattus norvegicus (Norway rat)	Ki	59.1670	1	1
Signal transducer and activator of transcription 3	Homo sapiens (human)	IC50	14.0000	1	1
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	IC50	27.8298	2	2
Sodium- and chloride-dependent creatine transporter 1	Homo sapiens (human)	IC50	5.0000	1	1
Sodium-dependent dopamine transporter	Rattus norvegicus (Norway rat)	IC50	1,000.0000	1	1
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	IC50	3.7870	1	1
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	Ki	3.7560	1	1
Sodium-dependent serotonin transporter	Homo sapiens (human)	IC50	1.0000	1	1
Sodium-dependent serotonin transporter	Rattus norvegicus (Norway rat)	IC50	0.5050	2	2
Sodium/hydrogen exchanger	Amphiuma tridactylum (three-toed salamander)	IC50	8.7000	1	1
Sodium/hydrogen exchanger 1	Homo sapiens (human)	IC50	0.8000	1	1
Sodium/hydrogen exchanger 1	Oryctolagus cuniculus (rabbit)	IC50	0.0200	1	1
Sodium/hydrogen exchanger 1	Rattus norvegicus (Norway rat)	IC50	0.0100	1	1
Sodium/hydrogen exchanger 1	Oryctolagus cuniculus (rabbit)	Ki	0.0200	2	2
Sodium/hydrogen exchanger 1	Rattus norvegicus (Norway rat)	Ki	0.0100	2	2
Sodium/hydrogen exchanger 2	Oryctolagus cuniculus (rabbit)	IC50	0.5000	1	1
Sodium/hydrogen exchanger 2	Oryctolagus cuniculus (rabbit)	Ki	0.5000	2	2
Sodium/hydrogen exchanger 2	Rattus norvegicus (Norway rat)	Ki	0.0800	2	2
Sodium/hydrogen exchanger 3	Rattus norvegicus (Norway rat)	IC50	2.4000	1	1
Sodium/hydrogen exchanger 3	Rattus norvegicus (Norway rat)	Ki	2.4000	2	2
Sodium/hydrogen exchanger 5	Homo sapiens (human)	IC50	0.4200	1	1
Sodium/hydrogen exchanger 5	Homo sapiens (human)	Ki	0.4200	2	2
Solute carrier family 15 member 1	Rattus norvegicus (Norway rat)	Ki	8,000.0000	1	1
Solute carrier family 15 member 2	Homo sapiens (human)	IC50	28.0000	1	1
Solute carrier family 15 member 2	Rattus norvegicus (Norway rat)	Ki	66.0000	1	1
Solute carrier family 2, facilitated glucose transporter member 1	Homo sapiens (human)	IC50	0.2280	1	1
Solute carrier family 22 member 1	Homo sapiens (human)	IC50	16.6500	2	2
Solute carrier family 22 member 12	Homo sapiens (human)	IC50	2.0000	1	1
Solute carrier family 22 member 12	Rattus norvegicus (Norway rat)	IC50	18.0000	1	1
Solute carrier family 22 member 12	Homo sapiens (human)	Ki	5.7400	1	1
Solute carrier organic anion transporter family member 1A1	Rattus norvegicus (Norway rat)	Ki	18.2000	1	1
Solute carrier organic anion transporter family member 1A2	Homo sapiens (human)	Ki	51.0000	1	1
Solute carrier organic anion transporter family member 1A4	Rattus norvegicus (Norway rat)	Ki	1.4300	2	2
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	IC50	1.5000	4	4
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	Ki	9.0500	2	2
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	IC50	1.5000	1	1
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	Ki	3.2000	2	2
Solute carrier organic anion transporter family member 2B1	Homo sapiens (human)	IC50	65.0000	1	1
Solute carrier organic anion transporter family member 2B1	Homo sapiens (human)	Ki	63.0000	1	1
Sortase A	Streptococcus mutans	IC50	18.7000	1	2
Spike glycoprotein	Betacoronavirus England 1	IC50	1.1100	1	2
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	IC50	1.1100	1	2
Squalene monooxygenase	Rattus norvegicus (Norway rat)	IC50	0.6900	2	2
Stromelysin-1	Homo sapiens (human)	IC50	0.0104	9	9
Stromelysin-1	Homo sapiens (human)	Ki	0.0265	2	2
Structural capsid protein	Human immunodeficiency virus 1	IC50	0.0467	1	1
Sulfhydryl oxidase 1	Homo sapiens (human)	IC50	5.4000	1	1
SUMO-activating enzyme subunit 1	Homo sapiens (human)	IC50	2.2000	1	1
Telomerase reverse transcriptase	Homo sapiens (human)	IC50	1.0867	3	3
TGF-beta receptor type-1	Homo sapiens (human)	IC50	18.0000	2	2
Thioredoxin reductase 1, cytoplasmic	Homo sapiens (human)	IC50	107.3429	4	7
Thioredoxin reductase 2, mitochondrial	Homo sapiens (human)	IC50	120.2333	3	6
Thioredoxin reductase 3	Homo sapiens (human)	IC50	120.2333	3	6
Thiosulfate sulfurtransferase	Homo sapiens (human)	IC50	55.0750	2	4
Thromboxane-A synthase	Homo sapiens (human)	IC50	0.4940	1	1
Tissue factor	Homo sapiens (human)	IC50	1,166.6711	3	3
Tissue factor	Homo sapiens (human)	Ki	8,000.0000	1	1
Tissue-type plasminogen activator	Homo sapiens (human)	IC50	0.0910	1	1
toll-like receptor 9	Homo sapiens (human)	IC50	8.3620	1	1
Toxin B	Clostridioides difficile	IC50	0.0172	1	1
TPA: protein transporter TIM10	Saccharomyces cerevisiae S288C	IC50	10.0933	2	3
TPA: protein transporter TIM23	Saccharomyces cerevisiae S288C	IC50	0.8800	1	1
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	IC50	1.0000	1	1
transactivating tegument protein VP16 [Human herpesvirus 1]	Human alphaherpesvirus 1 (Herpes simplex virus type 1)	IC50	85.4210	1	1
Transcription factor p65	Homo sapiens (human)	IC50	35.8500	2	2
Transient receptor potential cation channel subfamily A member 1	Homo sapiens (human)	IC50	13.0000	1	1
Transient receptor potential cation channel subfamily A member 1	Rattus norvegicus (Norway rat)	IC50	10.2500	2	2
Transient receptor potential cation channel subfamily M member 8	Homo sapiens (human)	IC50	8.0533	3	3
Transient receptor potential cation channel subfamily M member 8	Rattus norvegicus (Norway rat)	IC50	0.1600	1	1
Transient receptor potential cation channel subfamily V member 1	Homo sapiens (human)	IC50	5.0667	3	3
Transient receptor potential cation channel subfamily V member 2	Homo sapiens (human)	IC50	1.5000	1	1
Transient receptor potential cation channel subfamily V member 2	Rattus norvegicus (Norway rat)	IC50	7.1667	3	3
Transient receptor potential cation channel subfamily V member 3	Homo sapiens (human)	IC50	66.0000	1	1
Transient receptor potential cation channel subfamily V member 4	Homo sapiens (human)	IC50	1.3000	1	1
Translocator protein	Rattus norvegicus (Norway rat)	IC50	0.0390	1	2
Transmembrane protease serine 2	Homo sapiens (human)	IC50	1.1100	1	2
Trypsin-1	Homo sapiens (human)	IC50	1,000.0000	1	1
Trypsin-2	Homo sapiens (human)	IC50	1,000.0000	1	1
Trypsin-3	Homo sapiens (human)	IC50	1,000.0000	1	1
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	Ki	1.7000	1	1
Tyrosinase	Homo sapiens (human)	IC50	5.0000	1	1
Tyrosinase	Mus musculus (house mouse)	IC50	0.0340	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	IC50	12.5054	5	5
Tyrosine-protein kinase Fyn	Homo sapiens (human)	IC50	4.2140	1	1
Tyrosine-protein kinase HCK	Homo sapiens (human)	IC50	0.1900	1	1
Tyrosine-protein kinase Lck	Homo sapiens (human)	IC50	2.1153	3	3
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	IC50	0.0090	2	2
Tyrosine-protein kinase SYK	Homo sapiens (human)	IC50	14.0800	2	2
Tyrosine-protein kinase Yes	Homo sapiens (human)	Ki	7.9000	1	1
UDP-glucose 4-epimerase	Homo sapiens (human)	IC50	0.0140	1	1
UDP-glucuronosyltransferase 2B7	Homo sapiens (human)	Ki	1,600.0000	1	1
Urease subunit alpha	Helicobacter pylori 26695	IC50	30.4725	4	4
Urease subunit alpha	Helicobacter pylori 26695	Ki	0.2260	1	1
Urease subunit beta	Helicobacter pylori 26695	IC50	30.4725	4	4
Urease subunit beta	Helicobacter pylori 26695	Ki	0.2260	1	1
Urokinase-type plasminogen activator	Homo sapiens (human)	IC50	0.0910	1	1
Urokinase-type plasminogen activator	Mus musculus (house mouse)	IC50	0.0910	1	1
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	IC50	0.0458	2	2
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Ki	0.0020	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	GI50	0.0330	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50	3.7676	57	59
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Ki	0.0075	4	4
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	IC50	0.0089	1	1
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Ki	0.0170	1	1
Vesicular glutamate transporter 3	Rattus norvegicus (Norway rat)	Ki	945.0000	2	2
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	IC50	100.8897	4	4
Voltage-dependent L-type calcium channel subunit alpha-1C	Rattus norvegicus (Norway rat)	IC50	100.0000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	Rattus norvegicus (Norway rat)	IC50	100.0000	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	IC50	62.3000	2	2
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	IC50	62.3000	2	2
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	IC50	62.3000	2	2
Voltage-dependent L-type calcium channel subunit alpha-1S	Rattus norvegicus (Norway rat)	IC50	100.0000	1	1
Voltage-dependent N-type calcium channel subunit alpha-1B	Homo sapiens (human)	IC50	7.0000	2	2
Voltage-dependent T-type calcium channel subunit alpha-1H	Homo sapiens (human)	IC50	2.0000	2	2
Xanthine dehydrogenase/oxidase	Homo sapiens (human)	IC50	272.4350	3	4

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	1	4
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	6.1000	3	5
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	EC50	0.0005	1	1
5-hydroxytryptamine receptor 4	Homo sapiens (human)	EC50	10.0000	1	1
5-hydroxytryptamine receptor 5A	Homo sapiens (human)	EC50	85.8470	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	8.1240	6	10
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	EC50	0.0168	1	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	4.0534	3	5
5'-AMP-activated protein kinase subunit beta-1	Homo sapiens (human)	EC50	0.0168	1	2
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	EC50	0.0168	1	2
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	20.3800	1	3
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	20.5780	1	3
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	30.0000	1	4
Acetylcholinesterase	Homo sapiens (human)	Kd	0.0170	1	1
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	1	3
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	1	3
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	16.2500	4	8
Activin receptor type-1	Homo sapiens (human)	Kd	18.8889	4	9
Activin receptor type-1B	Homo sapiens (human)	Kd	15.7500	4	8
Activin receptor type-2A	Homo sapiens (human)	Kd	10.0000	3	5
Activin receptor type-2B	Homo sapiens (human)	Kd	17.5000	4	8
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	1	2
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1	2
Adenine phosphoribosyltransferase	Homo sapiens (human)	Kd	30.0000	1	3
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	1	3
Adenosine receptor A1	Homo sapiens (human)	EC50	1.2000	1	1
Adenosine receptor A2a	Homo sapiens (human)	EC50	0.9500	1	1
Adenosine receptor A2b	Homo sapiens (human)	EC50	1.3150	2	2
Adenosine receptor A3	Homo sapiens (human)	EC50	0.0270	1	1
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	1	3
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	1	3
Albumin	Homo sapiens (human)	Kd	12.0000	1	1
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	4.1020	3	5
Alpha-synuclein	Homo sapiens (human)	Kd	3.5000	4	4
Amyloid-beta precursor protein	Homo sapiens (human)	EC50	8.4100	1	1
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	10.0000	3	5
Angiotensin-converting enzyme 2	Homo sapiens (human)	EC50	1.6330	1	3
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	4.1860	3	5
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	6.7152	8	12
Apelin receptor	Homo sapiens (human)	EC50	0.0129	28	29
Apelin receptor	Rattus norvegicus (Norway rat)	EC50	0.0045	4	4
Apelin receptor	Homo sapiens (human)	Kd	0.0005	1	1
Apelin receptor	Mus musculus (house mouse)	Kd	0.0045	1	1
Arachidonate 5-lipoxygenase-activating protein	Homo sapiens (human)	EC50	0.0059	1	1
Aryl hydrocarbon receptor	Homo sapiens (human)	EC50	0.3000	1	1
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DDX42	Homo sapiens (human)	Kd	30.0000	1	3
ATP-dependent RNA helicase DHX30	Homo sapiens (human)	Kd	30.0000	1	3
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	17.5000	4	8
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	7.2400	3	5
Aurora kinase A	Homo sapiens (human)	Kd	13.5222	5	9
Aurora kinase B	Homo sapiens (human)	Kd	10.3696	4	8
Aurora kinase C	Homo sapiens (human)	Kd	3.0400	5	7
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	4.3540	3	5
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	1	3
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	8.3967	6	10
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	17.5000	4	8
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	17.6167	3	6
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	10.5398	4	8
Breakpoint cluster region protein	Homo sapiens (human)	EC50	1.0000	1	1
Breakpoint cluster region protein	Homo sapiens (human)	Kd	30.0000	1	3
Bromodomain-containing protein 7	Homo sapiens (human)	Kd	11.0000	1	1
Bromodomain-containing protein 9	Homo sapiens (human)	Kd	17.0000	1	1
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	1.0750	1	2
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	3.6933	4	6
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	13.3667	5	9
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	4.1517	4	6
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	3.7717	4	6
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	4.3740	3	5
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	2.9971	5	7
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	4.5667	4	6
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	12.4844	5	9
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	7.7207	7	11
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	12.8489	4	9
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	18.5714	3	7
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	17.5000	4	8
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	1	3
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	13.3333	4	6
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	1	3
Cannabinoid receptor 1	Homo sapiens (human)	EC50	0.1868	14	14
Cannabinoid receptor 1	Mus musculus (house mouse)	EC50	0.2601	2	2
Cannabinoid receptor 1	Rattus norvegicus (Norway rat)	EC50	0.1631	2	2
Cannabinoid receptor 2	Rattus norvegicus (Norway rat)	EC50	0.0015	1	1
Cannabinoid receptor 2	Homo sapiens (human)	EC50	0.0288	17	17
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	11.3438	3	6
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	1.1250	2	4
Casein kinase I isoform delta	Homo sapiens (human)	Kd	7.6235	4	8
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	9.1307	5	10
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	10.7705	4	8
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	13.7912	4	8
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	10.4582	4	8
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	4.2124	3	5
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	10.5126	4	8
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	10.0000	1	2
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	1	3
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	18.8889	4	9
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	10.0000	3	5
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Homo sapiens (human)	Kd	21.6000	1	1
Chain A, Troponin C, slow skeletal and cardiac muscles	Homo sapiens (human)	Kd	1,100.0000	1	1
Choline-phosphate cytidylyltransferase A	Homo sapiens (human)	Kd	30.0000	1	2
Cholinesterase	Equus caballus (horse)	Kd	1.1500	1	1
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	1	3
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	15.1770	4	8
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	1	3
Cyclin-dependent kinase 10	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	21.1600	1	3
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	16.9036	2	5
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	4.1620	3	5
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	10.0000	2	3
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	10.2785	6	11
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	10.8100	4	8
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	9.1833	4	6
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	16.6667	5	9
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	13.8780	4	8
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	16.8857	3	7
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	1	3
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	10.2740	4	8
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	10.0000	3	5
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	16.0279	4	9
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	4.0667	2	3
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	10.0000	2	3
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	20.0000	3	6
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	17.1125	4	8
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	5.1403	7	12
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	3
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Cytochrome P450 1A2	Homo sapiens (human)	EC50	0.0123	1	1
Cytochrome P450 2B6	Homo sapiens (human)	EC50	1.3000	1	1
Cytochrome P450 2C19	Homo sapiens (human)	EC50	0.0123	1	1
Cytochrome P450 2E1	Homo sapiens (human)	EC50	0.0005	1	1
Cytochrome P450 3A4	Homo sapiens (human)	EC50	0.0123	1	1
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	10.0000	3	5
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	1	4
Death-associated protein kinase 1	Homo sapiens (human)	Kd	4.0720	3	5
Death-associated protein kinase 2	Homo sapiens (human)	Kd	3.0557	5	7
Death-associated protein kinase 3	Homo sapiens (human)	Kd	3.4184	6	9
delta-type opioid receptor	Homo sapiens (human)	EC50	36.8205	2	2
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	1	4
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	1	3
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	15.3625	4	8
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	1	3
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	1	3
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	1	3
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	1	3
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	5.6500	1	2
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	10.3712	4	8
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	10.1509	4	8
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	16.4625	4	8
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	8.1400	3	5
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	12.9942	2	5
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	18.3556	4	9
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	10.0000	1	2
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	4.2462	8	12
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	6.8118	8	12
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	13.8875	5	8
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	9.1955	8	12
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	12.9708	6	12
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	17.5000	4	8
Dual specificity testis-specific protein kinase 2	Homo sapiens (human)	Kd	30.0000	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	10.5833	4	7
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	4.5067	4	6
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	2.9525	3	4
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	4.1080	3	5
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	1	3
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	1	3
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	17.5000	4	8
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	17.5000	4	8
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	5.2600	3	5
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	17.5000	4	8
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	15.2333	5	9
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	1.2133	4	6
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	11.8620	6	10
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	10.0000	3	5
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	3.3371	5	7
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	16.3111	5	9
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	18.8889	4	9
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	16.5300	5	10
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	15.8250	3	6
Epidermal growth factor receptor	Homo sapiens (human)	Kd	6.6490	30	54
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	11.1111	5	9
Estrogen receptor	Rattus norvegicus (Norway rat)	EC50	12.0430	1	2
Estrogen receptor beta	Rattus norvegicus (Norway rat)	EC50	12.0430	1	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)	Kd	30.0000	1	2
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	22.0000	2	5
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	1	2
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	1	3
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	9.6617	5	9
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	3.2529	5	7
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	4.1245	7	11
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	8.4200	3	5
Focal adhesion kinase 1	Homo sapiens (human)	Kd	11.2540	6	10
G protein-coupled receptor GPR35	Rattus norvegicus (Norway rat)	EC50	66.0000	1	1
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	3.4267	2	3
G protein-coupled receptor kinase 6	Homo sapiens (human)	Kd	20.5383	1	3
G-protein coupled bile acid receptor 1	Homo sapiens (human)	EC50	54.8875	3	4
G-protein coupled receptor 35	Homo sapiens (human)	EC50	164.6118	11	11
Gamma-butyrobetaine dioxygenase	Homo sapiens (human)	Kd	4.1000	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	20.4083	1	3
Glucagon-like peptide 1 receptor	Homo sapiens (human)	EC50	0.0082	9	9
Glucagon-like peptide 1 receptor	Homo sapiens (human)	Kd	6.2700	1	1
Glutamate receptor 1	Rattus norvegicus (Norway rat)	EC50	0.1704	2	2
Glutamate receptor 2	Rattus norvegicus (Norway rat)	EC50	0.1704	2	2
Glutamate receptor 3	Rattus norvegicus (Norway rat)	EC50	0.1704	2	2
Glutamate receptor 4	Rattus norvegicus (Norway rat)	EC50	0.1704	2	2
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	Kd	5.0186	2	2
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	Kd	5.0186	2	2
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	Kd	5.0186	2	2
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	Kd	5.0186	2	2
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	Kd	5.0186	2	2
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	Kd	5.0186	2	2
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	Kd	5.0186	2	2
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	1	3
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	1	3
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	1	3
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	15.6167	5	9
Glycogen synthase kinase-3 beta	Homo sapiens (human)	EC50	38.1100	2	2
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	15.4250	4	8
glycogen synthase kinase-3 beta isoform 1	Homo sapiens (human)	EC50	150.1197	1	2
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	1	3
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	1	2
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	1	3
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	10.5308	8	13
hexokinase HKDC1	Homo sapiens (human)	EC50	38.8000	1	1
hexokinase-1 isoform HKI	Homo sapiens (human)	EC50	41.9000	1	1
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	7.5255	7	11
Histamine H3 receptor	Rattus norvegicus (Norway rat)	EC50	500.0000	1	1
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	5.0938	3	4
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	3.3540	2	3
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	2.5780	3	4
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	3.4400	2	3
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	3.6667	2	3
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	3.6800	2	3
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	10.0000	2	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	10.4489	4	8
Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)	Kd	30.0000	1	3
Insulin receptor	Homo sapiens (human)	Kd	11.1860	6	10
Insulin receptor-related protein	Homo sapiens (human)	Kd	4.2580	3	5
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	14.7250	4	8
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	1	2
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	4.4020	3	5
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	14.4226	4	7
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	14.1025	4	8
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	14.5382	2	5
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	5.0465	2	4
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	5.0800	3	5
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	5.4650	1	2
LIM domain kinase 1	Homo sapiens (human)	Kd	18.8889	4	9
LIM domain kinase 2	Homo sapiens (human)	Kd	18.8889	4	9
Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)	Kd	30.0000	1	3
Lymphocyte antigen 96	Homo sapiens (human)	Kd	379.0000	1	1
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	4.0013	3	5
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	21.4286	3	7
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	17.5000	4	8
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	17.5000	4	8
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	8.7800	3	5
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	9.1400	3	5
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	9.3819	5	9
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	15.1000	4	8
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	3.3677	24	50
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	6.7906	4	8
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	9.2333	2	3
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	1	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	17.5000	4	8
Metabotropic glutamate receptor 1	Homo sapiens (human)	EC50	100.0000	1	1
Metabotropic glutamate receptor 2	Homo sapiens (human)	EC50	0.0027	3	3
Metabotropic glutamate receptor 3	Homo sapiens (human)	EC50	0.0046	3	3
Metabotropic glutamate receptor 4	Homo sapiens (human)	EC50	21.1000	1	1
Metabotropic glutamate receptor 6	Homo sapiens (human)	EC50	50.2005	2	2
Metabotropic glutamate receptor 7	Homo sapiens (human)	EC50	50.0792	2	2
Metabotropic glutamate receptor 8	Homo sapiens (human)	EC50	1.6900	2	2
Microtubule-associated protein tau	Homo sapiens (human)	EC50	0.3600	2	2
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	3.4667	2	3
Midasin	Homo sapiens (human)	Kd	30.0000	1	5
Misshapen-like kinase 1	Homo sapiens (human)	Kd	10.0145	3	4
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	18.8889	4	9
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	12.7128	5	9
Mitogen-activated protein kinase 11	Homo sapiens (human)	EC50	0.0600	1	1
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	12.0400	6	10
Mitogen-activated protein kinase 12	Homo sapiens (human)	EC50	0.0600	1	1
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	4.9586	5	7
Mitogen-activated protein kinase 13	Homo sapiens (human)	EC50	0.0600	1	1
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	7.5025	3	4
Mitogen-activated protein kinase 14	Homo sapiens (human)	EC50	0.0600	2	2
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	10.0064	8	12
Mitogen-activated protein kinase 14	Mus musculus (house mouse)	Kd	0.0200	2	2
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	17.5000	4	8
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	17.5000	4	8
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	3	5
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	10.0000	3	5
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	17.4875	4	8
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	13.7111	5	9
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	12.5283	5	9
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	20.0000	3	6
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	10.0000	3	5
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	10.8746	4	8
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	5.0500	1	2
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	3.3967	2	3
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	4.2000	2	3
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	3.3447	2	3
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	12.0835	3	6
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	16.1000	4	8
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	12.2840	3	6
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	15.3444	5	9
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	18.8889	4	9
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	20.0000	3	6
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	3.3953	2	3
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	6.0400	3	5
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	10.0371	4	8
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	18.3388	3	6
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	10.1335	4	8
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	8.5110	4	8
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	8.1471	6	10
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	23.3768	1	4
mu-type opioid receptor isoform MOR-1	Homo sapiens (human)	EC50	51.0195	2	2
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	1	3
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	4.2940	3	5
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	2.8944	5	7
Myosin light chain kinase 3	Homo sapiens (human)	Kd	20.0046	2	5
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	4.0090	3	5
Myosin light chain kinase, smooth muscle	Gallus gallus (chicken)	Kd	5.0115	1	2
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	14.0863	5	10
Myosin-10	Homo sapiens (human)	Kd	30.0000	1	2
Myosin-14	Homo sapiens (human)	Kd	30.0000	1	4
Myosin-IIIa	Homo sapiens (human)	Kd	8.6200	3	5
Myosin-IIIb	Homo sapiens (human)	Kd	6.7000	3	5
Myotonin-protein kinase	Homo sapiens (human)	Kd	10.0000	3	5
NAD kinase	Homo sapiens (human)	Kd	1.7800	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	1	4
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	14.0050	4	8
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	10.6836	6	11
NPC1-like intracellular cholesterol transporter 1	Homo sapiens (human)	EC50	8.7000	1	1
NT-3 growth factor receptor	Homo sapiens (human)	Kd	7.0600	3	5
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	4.0288	3	5
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	13.8062	4	8
Nuclear factor erythroid 2-related factor 2	Homo sapiens (human)	EC50	21.0000	1	1
Nuclear receptor subfamily 1 group I member 2	Homo sapiens (human)	EC50	3.6991	10	11
Nuclear receptor subfamily 1 group I member 2	Rattus norvegicus (Norway rat)	EC50	4.0000	1	1
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	4
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	1	3
Oxysterols receptor LXR-alpha	Homo sapiens (human)	EC50	1.3333	3	3
Oxysterols receptor LXR-alpha	Homo sapiens (human)	Kd	2.2000	1	1
Oxysterols receptor LXR-beta	Homo sapiens (human)	EC50	125.2000	1	1
Oxysterols receptor LXR-beta	Homo sapiens (human)	Kd	73.2000	1	1
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	1	3
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	10.0000	1	2
Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)	Kd	30.0000	1	3
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	1	3
Peroxisome proliferator-activated receptor alpha	Homo sapiens (human)	EC50	3.5000	1	1
Peroxisome proliferator-activated receptor gamma	Homo sapiens (human)	EC50	16.3500	2	2
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	1	3
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	7.2400	3	5
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	6.3000	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	10.0000	21	33
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	10.0000	2	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	4.0234	3	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	22.0000	2	5
Phospholipase A2	Homo sapiens (human)	Kd	10.0000	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	8.0757	6	10
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	2.8795	5	7
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	4.0005	3	5
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	8.0005	6	10
Poly [ADP-ribose] polymerase 1	Homo sapiens (human)	EC50	0.0200	1	1
Poly [ADP-ribose] polymerase 1	Homo sapiens (human)	Kd	0.1100	1	1
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	Kd	8.9000	1	1
Polycomb protein EED	Homo sapiens (human)	Kd	15.1000	1	1
POsterior Segregation	Caenorhabditis elegans	EC50	96.2865	1	2
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	1	3
Procathepsin L	Homo sapiens (human)	EC50	1.6330	1	3
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	5.0175	1	2
Protein delta homolog 1	Homo sapiens (human)	Kd	0.1000	1	1
Protein kinase C alpha type	Homo sapiens (human)	Kd	21.2000	3	5
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	1	3
Protein kinase C delta type	Homo sapiens (human)	Kd	14.3486	4	8
Protein kinase C epsilon type	Homo sapiens (human)	Kd	10.0000	3	5
Protein kinase C eta type	Homo sapiens (human)	Kd	10.0000	3	5
Protein kinase C iota type	Homo sapiens (human)	Kd	23.3333	2	6
Protein kinase C theta type	Homo sapiens (human)	Kd	15.3625	4	8
Protein kinase C zeta type	Homo sapiens (human)	Kd	30.0000	1	2
Protein mono-ADP-ribosyltransferase PARP3	Homo sapiens (human)	Kd	0.7000	1	1
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	17.0246	4	10
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	14.6000	5	9
Prothrombin	Homo sapiens (human)	Kd	0.0078	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	6.3240	11	19
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	10.0000	3	5
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	12.2222	5	9
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	1	3
Pyridoxal kinase	Homo sapiens (human)	Kd	25.2042	1	5
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	1	2
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	17.5000	4	8
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	14.7625	4	8
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	17.5000	4	8
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	6.3920	3	5
Ras-related C3 botulinum toxin substrate 1	Homo sapiens (human)	Kd	30.0000	1	1
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1	4
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	1	4
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	1	3
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	10.0000	3	5
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	2	3
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	8.2667	2	3
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	3.5800	4	6
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	13.5720	5	9
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	3
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	4.7333	2	3
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	4.6167	25	39
recombinase A	Mycobacterium tuberculosis H37Rv	EC50	78.6500	2	2
Replicase polyprotein 1a	Severe acute respiratory syndrome-related coronavirus	EC50	1.6330	1	3
Replicase polyprotein 1ab	Betacoronavirus England 1	EC50	1.6330	1	3
Replicase polyprotein 1ab	Human coronavirus 229E	EC50	1.6330	1	3
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	EC50	4.8313	4	7
Replicase polyprotein 1ab	Severe acute respiratory syndrome-related coronavirus	EC50	3.9138	2	5
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	Kd	11.9500	2	2
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	11.9710	3	6
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	10.1859	4	7
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	3.5267	2	3
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	3.4533	2	3
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	7.2516	7	13
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	4.8898	8	12
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	8.4966	6	10
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	8.4542	7	13
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	7.5663	9	15
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	11.3615	7	13
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	16.7080	3	6
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	12.1577	1	3
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1	3
RPL19A	Saccharomyces cerevisiae (brewer's yeast)	EC50	0.7570	2	2
S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)	Kd	30.0000	1	3
Septin-9	Homo sapiens (human)	Kd	30.0000	1	4
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	9.4069	5	9
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	11.1470	6	10
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	2.8636	5	7
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	2.9671	5	7
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	7.7533	4	7
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	4.1740	3	5
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	10.4068	4	8
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	10.3214	4	8
Serine/threonine-protein kinase 3	Mus musculus (house mouse)	Kd	0.1600	1	1
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	5.6500	1	2
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	6.8400	3	5
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	4.0102	3	5
serine/threonine-protein kinase 33 isoform a	Homo sapiens (human)	EC50	9.5830	1	1
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	4.2000	2	3
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	5.5767	4	6
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	3.6067	2	3
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	10.5512	5	8
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	11.7988	6	12
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	1	3
Serine/threonine-protein kinase ATR	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	13.0343	7	14
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	6.1000	3	5
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	4.6600	3	5
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	10.5242	4	8
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	3.3390	2	3
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	4.1860	3	5
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	7.3351	4	8
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	9.4782	4	8
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	4.2220	3	5
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	5.6200	3	5
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	4.0660	3	5
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	14.1880	3	5
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	7.1004	4	8
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	4.2760	3	5
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	10.0000	2	3
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	4.7200	3	5
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	9.3626	5	9
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	16.5500	4	8
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	15.6750	4	8
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	15.1000	4	8
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	12.5523	4	9
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	10.8124	4	8
Serine/threonine-protein kinase N3	Homo sapiens (human)	Kd	22.5248	1	4
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	18.8889	4	9
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	11.5200	6	10
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	22.0000	2	5
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	13.1857	4	7
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	17.5000	4	8
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	3.9000	2	3
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	15.0062	4	8
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	3.6867	2	3
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	17.5000	4	8
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	4.0096	3	5
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	14.6125	4	8
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	4.3840	3	5
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	9.5333	4	6
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	17.5000	4	8
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	9.1667	4	6
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	5.4400	3	5
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	5.0435	1	2
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	17.5000	4	8
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	6.4667	2	3
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	11.1330	6	10
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	3.5933	2	3
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	10.0000	3	5
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	4.0210	3	5
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	2.5745	3	4
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	6.2800	3	5
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	5.1000	1	2
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	5.1100	1	2
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	5.9200	3	5
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	13.9675	4	8
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	18.9833	3	6
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	13.7642	4	8
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	14.1850	5	8
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	22.0000	2	5
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	16.7367	3	6
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	11.9570	3	6
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	7.4000	3	5
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	4.4440	3	5
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	4.1980	3	5
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	12.0360	3	6
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	3.3420	2	3
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	11.8682	3	6
Serine/threonine-protein kinase ULK3	Mus musculus (house mouse)	Kd	0.1100	1	1
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	16.8667	3	6
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	1	3
Signal recognition particle receptor subunit alpha	Homo sapiens (human)	Kd	30.0000	1	3
Signal transducer and activator of transcription 1-alpha/beta	Homo sapiens (human)	Kd	0.7000	1	1
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	5.3200	1	2
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	EC50	57.3065	1	2
Sodium/bile acid cotransporter	Homo sapiens (human)	Kd	64.3000	1	1
Spike glycoprotein	Betacoronavirus England 1	EC50	1.6330	1	3
Spike glycoprotein	Severe acute respiratory syndrome-related coronavirus	EC50	1.6330	1	3
SRSF protein kinase 1	Homo sapiens (human)	Kd	4.1500	3	5
SRSF protein kinase 2	Homo sapiens (human)	Kd	4.1140	3	5
SRSF protein kinase 3	Homo sapiens (human)	Kd	3.3727	2	3
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	6.8649	6	11
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	1	3
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	3.4267	2	3
streptokinase A precursor	Streptococcus pyogenes M1 GAS	EC50	4.8703	2	3
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	1	3
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	1	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	4
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	7.7800	3	5
TGF-beta receptor type-1	Homo sapiens (human)	Kd	16.7750	4	8
TGF-beta receptor type-2	Homo sapiens (human)	Kd	15.4500	4	8
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	1	3
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	5.7865	6	11
Transient receptor potential cation channel subfamily A member 1	Homo sapiens (human)	EC50	0.6400	2	2
Transient receptor potential cation channel subfamily A member 1	Rattus norvegicus (Norway rat)	EC50	2.5667	3	3
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	1	2
Transient receptor potential cation channel subfamily V member 1	Homo sapiens (human)	EC50	5.6500	4	4
Transient receptor potential cation channel subfamily V member 2	Homo sapiens (human)	EC50	1.7000	1	1
Transient receptor potential cation channel subfamily V member 2	Rattus norvegicus (Norway rat)	EC50	1.7000	1	1
Transient receptor potential cation channel subfamily V member 3	Homo sapiens (human)	EC50	1.0000	1	1
Transient receptor potential cation channel subfamily V member 4	Homo sapiens (human)	EC50	5.1000	1	1
Transmembrane protease serine 2	Homo sapiens (human)	EC50	1.6330	1	3
Transporter	Rattus norvegicus (Norway rat)	EC50	0.0005	1	1
Transthyretin	Homo sapiens (human)	EC50	8.6000	1	1
Transthyretin	Homo sapiens (human)	Kd	0.4000	2	2
Tubulin alpha-1A chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin alpha-1A chain	Rattus norvegicus (Norway rat)	Kd	10.0000	1	2
Tubulin alpha-1B chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin alpha-1C chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin alpha-3C chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin alpha-3E chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin alpha-4A chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-1 chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-2A chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-2B chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-3 chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-4A chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-4B chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-6 chain	Homo sapiens (human)	Kd	149.7630	1	2
Tubulin beta-8 chain	Homo sapiens (human)	Kd	149.7630	1	2
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	EC50	0.2040	1	1
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	EC50	0.2040	1	1
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	3
Tyrosine-protein kinase ABL1	Homo sapiens (human)	EC50	1.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	4.8334	40	75
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	14.4200	5	10
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	4.0390	3	5
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	16.5125	4	8
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	17.5000	4	8
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	9.6332	5	9
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	14.1100	4	8
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	5.8787	6	9
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	11.0656	5	9
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	14.5460	5	10
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	9.7648	5	9
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	4.0078	3	5
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	7.8954	8	13
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	7.4529	5	7
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	4.7200	3	5
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	7.6616	5	9
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	10.3005	6	11
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	8.3463	4	6
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	8.7800	3	5
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	4.0294	3	5
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	4.0054	3	5
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	10.0000	3	5
Tyrosine-protein kinase SYK	Homo sapiens (human)	EC50	300.0000	1	1
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	17.5000	4	8
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	17.5000	4	8
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	7.8000	3	5
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	9.0398	5	9
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	10.0000	3	5
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1	3
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	1	2
Uncharacterized aarF domain-containing protein kinase 5	Homo sapiens (human)	Kd	30.0000	1	2
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	22.6078	1	4
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	4.6000	2	3
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	4.0011	3	5
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	2.5044	6	8
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	2.8886	5	7
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Wee1-like protein kinase	Homo sapiens (human)	Kd	14.1625	4	8
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	3
Zinc finger protein mex-5	Caenorhabditis elegans	EC50	57.3065	1	2

Other Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
5-hydroxytryptamine receptor 1A	Rattus norvegicus (Norway rat)	AC50	85.0000	1	1
5-hydroxytryptamine receptor 1D	Homo sapiens (human)	KA	35.0000	1	1
Adenosine receptor A1	Homo sapiens (human)	Affinity constant	0.0030	1	1
Adenosine receptor A1	Rattus norvegicus (Norway rat)	EC25	0.0100	1	1
Adenosine receptor A2a	Homo sapiens (human)	Affinity constant	30.0000	1	1
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	EC25	0.0100	1	1
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	Ratio	0.1240	1	2
Adenosine receptor A2b	Homo sapiens (human)	Affinity constant	30.0000	1	1
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	EC25	0.0100	1	1
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	Ratio	0.1240	1	2
Albumin	Bos taurus (cattle)	Kdiss	2.9000	1	1
Alpha-2A adrenergic receptor	Homo sapiens (human)	EC5	0.0020	1	1
Amyloid-beta precursor protein	Homo sapiens (human)	DC50	0.7550	2	2
Arylacetamide deacetylase	Homo sapiens (human)	Km	200.0000	1	2
ATP-dependent translocase ABCB1	Homo sapiens (human)	AC50	85.0000	1	1
Bile salt export pump	Homo sapiens (human)	Km	11.9000	1	1
Bile salt export pump	Rattus norvegicus (Norway rat)	Km	4.1000	1	1
Breakpoint cluster region protein	Homo sapiens (human)	AC50	45.0000	1	1
cAMP-dependent protein kinase catalytic subunit alpha isoform Calpha1	Homo sapiens (human)	AC50	1.1975	2	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	AC50	45.0000	1	1
Cannabinoid receptor 1	Homo sapiens (human)	K	1.0400	1	1
Cannabinoid receptor 1	Mus musculus (house mouse)	K	0.3800	1	1
Cannabinoid receptor 1	Homo sapiens (human)	Kb	2.2000	1	1
Cannabinoid receptor 1	Homo sapiens (human)	Log Ki	0.0003	1	1
Cannabinoid receptor 2	Homo sapiens (human)	Log Ki	0.0006	1	1
Carbonic anhydrase 1	Homo sapiens (human)	KA	1.3000	2	2
Carbonic anhydrase 2	Homo sapiens (human)	KA	35.0000	2	2
Carbonic anhydrase 4	Bos taurus (cattle)	KA	18.0000	2	2
Carbonic anhydrase 4	Homo sapiens (human)	KA	15.0000	1	1
Caspase 6, apoptosis-related cysteine peptidase	Homo sapiens (human)	AC50	1.6000	1	1
CDK5	Homo sapiens (human)	AC50	5.5590	1	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	Homo sapiens (human)	AC50	5.5590	1	1
Cytochrome P450 1A2	Homo sapiens (human)	INH	10.0000	1	1
Cytochrome P450 1A2	Homo sapiens (human)	Km	15.0000	1	1
Cytochrome P450 2C9	Homo sapiens (human)	Km	5.4000	1	1
Cytochrome P450 2D6	Homo sapiens (human)	INH	3.6000	1	1
Cytochrome P450 3A4	Homo sapiens (human)	INH	10.0000	1	1
Dihydrofolate reductase	Homo sapiens (human)	Activity	0.9200	1	1
Dihydrolipoyl dehydrogenase	Plasmodium falciparum (malaria parasite P. falciparum)	Km	49.0000	1	1
Dihydrolipoyl dehydrogenase, mitochondrial	Sus scrofa (pig)	Km	28.0000	1	1
DNA repair protein RAD52 homolog isoform a	Homo sapiens (human)	AC50	0.9360	1	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	Rattus norvegicus (Norway rat)	AC50	3.1060	1	1
EWS/FLI fusion protein	Homo sapiens (human)	AbsAC35_uM	40.2500	1	1
FAD-linked sulfhydryl oxidase ALR	Homo sapiens (human)	AC50	0.7780	1	1
FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	Mycobacterium tuberculosis H37Rv	AC50	89.1000	1	1
Glutamate receptor 1	Rattus norvegicus (Norway rat)	Kb	86.0000	2	4
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Kb	86.0000	2	4
Glutamate receptor 3	Rattus norvegicus (Norway rat)	Kb	86.0000	2	4
Glutamate receptor 4	Rattus norvegicus (Norway rat)	Kb	86.0000	2	4
Glutamate receptor ionotropic, kainate 1	Rattus norvegicus (Norway rat)	Kb	69.5000	1	2
Glutamate receptor ionotropic, kainate 2	Rattus norvegicus (Norway rat)	Kb	69.5000	1	2
Glutamate receptor ionotropic, kainate 3	Rattus norvegicus (Norway rat)	Kb	69.5000	1	2
Glutamate receptor ionotropic, kainate 4	Rattus norvegicus (Norway rat)	Kb	69.5000	1	2
Glutamate receptor ionotropic, kainate 5	Rattus norvegicus (Norway rat)	Kb	69.5000	1	2
Glutamate receptor ionotropic, NMDA 1	Rattus norvegicus (Norway rat)	Kb	53.7311	4	9
Glutamate receptor ionotropic, NMDA 2A	Rattus norvegicus (Norway rat)	Kb	53.7311	4	9
Glutamate receptor ionotropic, NMDA 2B	Homo sapiens (human)	Kapp	6,444.5000	20	20
Glutamate receptor ionotropic, NMDA 2B	Rattus norvegicus (Norway rat)	Kb	53.7311	4	9
Glutamate receptor ionotropic, NMDA 2C	Rattus norvegicus (Norway rat)	Kb	53.7311	4	9
Glutamate receptor ionotropic, NMDA 2D	Rattus norvegicus (Norway rat)	Kb	53.7311	4	9
Glutamate receptor ionotropic, NMDA 3A	Rattus norvegicus (Norway rat)	Kb	53.7311	4	9
Glutamate receptor ionotropic, NMDA 3B	Rattus norvegicus (Norway rat)	Kb	53.7311	4	9
Glutathione reductase, mitochondrial	Homo sapiens (human)	Km	6.3000	1	1
H3 histone acetyltransferase	Candida albicans SC5314	AC50	1.5500	1	1
heat shock protein 90, putative	Plasmodium falciparum 3D7	AC50	3.9760	1	2
heat shock protein HSP 90-alpha isoform 2	Homo sapiens (human)	AC50	3.2575	1	2
Histone acetyltransferase KAT8	Homo sapiens (human)	K0.5	205.0000	3	3
Histone acetyltransferase KAT8	Homo sapiens (human)	Km	1.7667	3	3
Histone acetyltransferase p300	Homo sapiens (human)	INH	8.5000	1	1
hypothetical protein CAALFM_CR05890CA	Candida albicans SC5314	AC50	1.5500	1	1
Ileal sodium/bile acid cotransporter	Homo sapiens (human)	Km	4.1000	1	1
Lactoperoxidase	Bos taurus (cattle)	Km	0.3200	1	1
Metabotropic glutamate receptor 1	Homo sapiens (human)	Activity	100.0000	1	1
Metabotropic glutamate receptor 2	Homo sapiens (human)	Activity	0.0030	1	1
Metabotropic glutamate receptor 3	Homo sapiens (human)	Activity	0.0050	1	1
Metabotropic glutamate receptor 4	Homo sapiens (human)	Activity	21.0000	1	1
Metabotropic glutamate receptor 5	Homo sapiens (human)	Activity	100.0000	1	1
Metabotropic glutamate receptor 6	Homo sapiens (human)	Activity	0.4000	1	1
Metabotropic glutamate receptor 7	Homo sapiens (human)	Activity	100.0000	1	1
Metabotropic glutamate receptor 8	Homo sapiens (human)	Activity	2.0000	1	1
Microtubule-associated protein tau	Homo sapiens (human)	DC50	200.0000	1	1
Mu-type opioid receptor	Rattus norvegicus (Norway rat)	Km	13.3000	1	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	Homo sapiens (human)	Km	15.0000	1	1
NAD-dependent protein deacetylase sirtuin-6	Homo sapiens (human)	EC1.5	227.5000	1	1
Pancreatic triacylglycerol lipase	Sus scrofa (pig)	ED50	10.0000	1	1
PAX8	Homo sapiens (human)	AC50	20.9400	1	1
Peroxisome proliferator-activated receptor delta	Homo sapiens (human)	Emax	68.0000	1	1
Plasma kallikrein	Homo sapiens (human)	K0.5	514.0000	1	1
protein AF-9 isoform a	Homo sapiens (human)	AC50	4.0800	1	1
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	INH	0.0566	2	2
replicative DNA helicase	Mycobacterium tuberculosis H37Rv	AC50	58.1800	2	2
serine/threonine-protein kinase 33 isoform a	Homo sapiens (human)	AC50	9.3400	2	3
Sodium/bile acid cotransporter	Rattus norvegicus (Norway rat)	Km	14.0000	1	1
Solute carrier family 22 member 2	Homo sapiens (human)	Km	34.0000	1	1
Solute carrier organic anion transporter family member 1A1	Rattus norvegicus (Norway rat)	Km	13.0000	1	1
Solute carrier organic anion transporter family member 1A2	Homo sapiens (human)	Km	19.0000	1	1
Solute carrier organic anion transporter family member 1A4	Rattus norvegicus (Norway rat)	Km	17.0000	1	1
Solute carrier organic anion transporter family member 1A5	Rattus norvegicus (Norway rat)	Km	5.9500	1	2
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	Km	7.2500	2	2
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	Km	2.3000	1	1
Thioredoxin reductase 1, cytoplasmic	Homo sapiens (human)	Km	95.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	AC50	45.0000	1	1
UDP-glucuronosyltransferase 1-6	Homo sapiens (human)	Km	3,200.0000	1	1
UDP-glucuronosyltransferase 1A9	Homo sapiens (human)	Km	5,200.0000	1	1
UDP-glucuronosyltransferase 2B7	Homo sapiens (human)	Km	2,100.0000	1	1
Vitamin K-dependent gamma-carboxylase	Homo sapiens (human)	Km	13.3000	1	1

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