Page last updated: 2024-09-28

Cancer of Esophagus

Synonyms(6)

Synonym
Neoplasms, Esophageal
Esophagus Cancer
Cancer of the Esophagus
Esophagus Neoplasm
Cancer of Esophagus
Esophageal Cancer

Research Excerpts

Overview

ExcerptReference
"Most patients with esophageal cancer are relatively old and have often multiorgan dysfunction."( Hioki, K; Hiramatsu, Y; Kawaguchi, Y; Kojima, Y; Yamamoto, M; Yamanaka, H, 1991)
"The incidence of esophageal cancer is much higher in men than in women and the prognosis is generally worse in men than in women."( Hattori, T; Hirai, T; Kawano, K; Mukaida, H; Niimoto, M; Toge, T; Yamashita, Y, 1989)
"Esophageal cancer is a complex and multifactorial problem."( Chui, SX; Feng, L; Lu, SH; Luo, FJ; Montesano, R; Rajewsky, MF; Saffhill, R; Umbenhauer, D; Zhang, MS, 1986)
"The etiology of cancer of the esophagus is known to be complex and composed of multiple factors, those caused by the environment being of greatest importance."( Tollefson, L, 1985)
"Since esophageal cancer is an important cause of cancer deaths in many parts of the world, information as to factors which can enhance protective systems of this organ may be of value."( Chuan, J; Sparnins, VL; Wattenberg, LW, 1982)
"Patients with T4 esophageal cancer are expected to have long term survival from extended operations when their cancer have no distant metastasis, and no or minor regional lymph node metastasis, are resected completely by combined resection of invaded neighboring organs, and responders to preoperative chemo and/or radiotherapy."( Ayabe, H, 1997)
"Locally advanced esophageal cancer is rarely operable and has a dismal prognosis."( Ancona, E; Bonavina, L; Castoro, C; Chiarion-Sileni, V; Merigliano, S; Peracchia, A; Ruol, A; Santi, S, 1997)
"Squamous cell cancer of the esophagus is the most common cancer among black South African males, and 60% of patients present with localized inoperable disease."( Burger, W; Falkson, CI; Falkson, G; Nel, JS; Schoeman, L; Slabber, CF, 1998)
"Esophageal cancer is a major cause of morbidity and mortality worldwide."( Beauchamp, RD; Blanke, CD; Choy, H; Johnson, DH; Leach, S; Roberts, J; Teng, M; Washington, K, 1999)
"Oesophageal cancer is the fifth most frequent cause of cancer death world wide and most of these cancers occur in developing countries."( Hainaut, P; Montesano, R, 1998)
"Local control of esophageal cancer is excellent following neoadjuvant chemotherapy and radiation therapy."( Adelstein, DJ; Becker, M; Chidel, MA; Kupelian, PA; Rice, TW; Suh, JH, 1999)
"Esophageal cancer is the primary cause of malignant dysphagia, a major cause of morbidity and mortality."( Adler, DG; Baron, TH, 2001)
"Advanced esophageal cancers are highly malignant and frequently resistant to 5-fluorouracil (5-FU)."( Hamada, H; Ochiai, T; Shimada, H; Shimizu, T, 2001)
"Esophageal cancer is associated with the poorest prognosis among the digestive tract cancers, and chemotherapy is the treatment of choice for many patients."( Akiyama, S; Fujiwara, M; Hamada, H; Ito, K; Kasai, Y; Nakamura, H; Nakao, A; Sekiguchi, H, 2001)
"Esophageal cancer is treated optimally with a combined-modality approach according to most clinical investigators."( Jatoi, A; Thomas, CR, 2002)
"Esophageal cancer is a rare but highly virulent malignancy in the United States and Western Europe, and adenocarcinoma of the esophagus has had the most rapid rate of increase of any solid tumor malignancy."( Ilson, DH, 2002)
"Esophageal cancer is the most markedly increasing tumor entity in Western countries."( Barthel, B; Carayon, P; Faiss, S; Grabowski, P; Höpfner, M; Maaser, K; Scherübl, H; Sutter, AP; Zeitz, M, 2002)
"Since mucosal (T1a) esophageal cancer is well controlled by endoscopic treatment, chemoradiotherapy (CRTx) is not indicated."( Fujita, H; Hayabuchi, N; Matono, S; Sasahara, H; Shirouzu, K; Sueyoshi, S; Suzuki, G; Tanaka, T; Yamana, H, 2003)
"Esophageal cancer is an aggressive disease, and poor survival is achieved with surgery or chemoradiation therapy alone."( Anderson, SE; Bains, M; Ilson, DH; Kelsen, DP; Minsky, BD, 2003)
"Esophageal cancer is supposed to be more sensitive to chemotherapy compared to other gastrointestinal cancers."( Nabeya, Y; Ochiai, T, 2003)
"Esophageal cancer is one of the most lethal of all neoplasms."( Dehdashti, F; Siegel, BA, 2004)
"Esophageal cancer is a rare but highly virulent malignancy in the United States, and adenocarcinoma of the esophagus has had the most rapid rate of increase of any solid tumor malignancy."( Ilson, DH, 2004)
"Esophageal cancer is the ninth most common malignancy in the world and the seventh leading cause of death in American men."( Bubis, JA; Dragnev, KH; Rigas, JR, 2005)
"Esophageal cancer is a rare but highly virulent malignancy occurring in the United States and other Western countries."( Ilson, DH, 2004)
"Esophageal cancer is the sixth most common cause of cancer-related death worldwide."( Höpfner, M; Huether, A; Maaser, K; Scherübl, H; Sutter, AP, 2006)
"Esophageal cancers are highly lethal neoplasms which are generally refractory to conventional multidisciplinary interventions."( Nguyen, DM; Schrump, DS, 2005)
"Esophageal cancer is common worldwide, with poor prognosis."( Walle, T; Wen, X, 2007)
"Esophageal cancers are predominantly carcinomas, which are-due to their origin from the epithelial lining-visible by endoluminal view."( Brücher, BL; Sarbia, M; von Rahden, BH, 2006)
"Esophageal cancer is difficult to treat because of its rapid progression, and more effective therapeutic approaches are needed."( Fujisawa, T; Fujita, K; Ikeda, I; Masuda, T; Nakagama, H; Nakajima, A; Saitoh, S; Saubermann, LJ; Schaefer, K; Shimamura, T; Tachibana, M; Takahashi, H; Tomimoto, A; Wada, K; Yoneda, M; Yonemitsu, K, 2006)
"The incidence of esophageal cancer is markedly increased in patients with head and neck cancer, and the presence of esophageal cancer is associated with reduced survival rates."( Christoph, B; Grosse-Thie, W; Kloeppel, G; Middelberg-Bisping, C; Moschler, O; Mueller, MK; Spahn, TW, 2006)
"The stage of esophageal cancer is currently determined by the anatomic TNM classification system as opposed to information about tumor biology."( Bryant, AS; Cerfolio, RJ, 2006)
"Esophageal cancer is a substantial health problem because of its usually late stage at diagnosis and poor prognosis."( Cao, L; Jiang, Y; Liang, ZD; Wu, TT; Xu, XC; Zhang, H, 2007)
"The prognosis of esophageal cancer is not only affected by TNM stage but also by the level of serum vascular endothelial growth factor (S-VEGF)."( Cai, L; Cui, NJ; Liu, MZ; Wang, XS; Zhang, CQ, 2006)
"Esophageal cancer is multifactorial disease involving environmental and genetic risk factors."( Ghoshal, UC; Jain, M; Kumar, S; Lal, P; Mittal, B; Tiwari, A, 2007)
"Advanced gastroesophageal cancer is an incurable condition and more research is desirable."( Ajani, JA; Cen, P, 2007)
"Locally advanced esophageal cancer is challenging to treat."( Alberts, SR; Fitch, TR; Foster, NR; Jatoi, A; Lair, BS; Martenson, JA; McLeod, HL; Moore, DF; Nichols, F; Tschetter, LK, 2007)
"Esophageal cancer is one of the most common malignancies in the world."( Cai, Y; Du, XL; Feng, YB; Han, YL; Hu, H; Luo, ML; Shen, XM; Wang, MR; Xu, X; Zhang, Y, 2007)
"Cachexia in gastroesophageal cancers is associated with changes in APRP concentrations."( Blachut, K; Diakowska, D; Gamian, A; Grabowski, K; Krzystek-Korpacka, M; Kustrzeba-Wojcicka, I; Matusiewicz, M; Terlecki, G, 2008)
"Esophageal cancer is the sixth leading causes of cancer-related death in the world."( Cho, CH; Liu, X; Srivastava, G; Sung, JJ; Wu, WK; Yu, L; Zhang, ST, 2008)
"Esophageal cancer is the eighth most common cancer worldwide, and one of the most fatal diseases despite modern medical treatment."( Chang, JY; Chang, KY; Chao, J; Yen, Y, 2008)
"Esophageal cancer is one of the most aggressive cancers in the world."( Fujiwara, Y; Fukazawa, T; Hatakeyama, S; Motoki, T; Naomoto, Y; Nishikawa, T; Ohara, T; Omori, O; Sakurama, K; Shirakawa, Y; Takaoka, M; Tanabe, S; Tanaka, N; Wang, ZG; Watanabe, N; Yamatsuji, T, 2008)
"Accurate staging of esophageal cancer is important when determining which patients will potentially benefit from curative surgery."( Berry, H; Gananadha, S; Hazebroek, EJ; Leibman, S; Marx, G; Osgood, L; Pavlakis, N; Shon, IH; Smith, GS, 2008)
"Esophageal cancer is the third most common malignancy of the alimentary tract."( Alavi, A; Basu, S; Heidari, P; Salavati, A, 2009)
"Oesophageal cancer is on the rise and often present in an advanced state."( Chilton, AP; Das, D; Jankowski, JA, 2009)
"Esophageal cancer is the third most common gastrointestinal malignancy with a poor long-term survival and high mortality."( Gu, P; Huang, G; Pan, L; Wu, S; Xue, H, 2009)
"Esophageal cancer is a frequently fatal malignancy, and is described in certain regions in Northeast India with an incidence of esophageal squamous cell carcinoma many fold higher than the rest of the population."( Chattopadhyay, I; Hewitt, SM; Kapur, S; Mishra, A; Purkayastha, J; Saxena, S; Sharma, J; Singh, A, 2009)
"Esophageal cancer is the eighth most common malignancy, and one of the leading causes of cancer-related deaths worldwide."( Cheung, AL; Li, B; Li, YY; Tsao, SW, 2009)
"Oesophageal cancer is the sixth most common form of cancer death globally with almost 400,000 deaths annually."( Chandanos, E; Lagergren, J, 2009)
"Esophageal cancer is a relatively rare form of cancer, but some world areas have a markedly higher incidence than others: China, Iceland, India, Japan and United Kingdom, appear to have a higher incidence, as well as the region around the Caspian Sea."( Dikshit, R; Ganesh, B; Talole, SD, 2009)
"Esophageal cancer is one of the most frequently occurring cancers in the world."( Fujiwara, Y; Fukazawa, T; Hatakeyama, S; Motoki, T; Naomoto, Y; Nishikawa, T; Ohara, T; Omori, O; Sakurama, K; Shirakawa, Y; Takaoka, M; Tanabe, S; Tanaka, N; Wang, ZG; Watanabe, N; Yamatsuji, T, 2010)
"Oesophageal cancer is an aggressive disease and the optimal therapy for patients with resectable tumours remains unclear."( Malthaner, R; Spithoff, K; Wong, RK, 2010)
"Complications of esophageal cancer are particularly frequent in cases of hypopharyngeal cancer in comparison to other head and neck tumors."( Egawa, S; Furuya, A; Kobayashi, S; Mori, T; Ono, T; Sanbe, T; Shimane, T; Suzaki, H, 2010)
"Esophageal cancer is the second most common cancer among Indian males and is mostly associated with tobacco smoking and alcohol consumption."( Devaraj, H; Devaraj, SN; Dhayaparan, D; Jayanthi, V; Parthasarathy, S, 2011)
"Behaviors of esophageal cancer are different according to the geographic distribution."( Bagheri, R; Maddah, G; Roodbari, S; Sadeghian, MH; Saedi, HS, 2011)
"Oesophageal cancer is a highly aggressive tumour entity with at present poor prognosis."( Alves, F; Dai, G; Dullin, C; Fischer, JW; Freudenberger, T; Homey, B; Jannasch, K; Knoefel, WT; Poscher, E; Prenzel, K; Savani, RC; Stoecklein, NH; Twarock, S, 2011)
"Barrett's esophageal cancer is usually included in gastroesophageal (GE) junction adenocarcinoma in Japanese people."( Abe, Y; Horii, T; Iijima, K; Imatani, A; Kikuchi, R; Koike, T; Ohara, S; Shimosegawa, T; Unakami, H, 2011)
"Esophageal cancer is an extremely lethal human disease."( Carballo, M; Maish, MS; Yetasook, A, 2011)
"Because most esophageal cancers are diagnosed at an advanced stage, a majority of patients require palliative dysphagia treatment."( Butruk, E; Fijuth, J; Kraszewska, E; Polkowski, M; Regula, J; Rupinski, M; Wronska, E; Zagorowicz, E, 2011)
"Esophageal cancer is one of the most common malignancies and is associated with a dismal prognosis."( Cao, Q; Ji, X; Liu, X; Lu, A; Meng, F; Sang, M; Shan, B; Wang, L, 2011)
"Esophageal cancer is an aggressive cancer with poor prognosis."( Hirano, S; Kondo, S; Miyamoto, M; Shichinohe, T; Tsuchikawa, T; Yamamura, Y, 2012)
"Oesophageal cancer is the ninth most common cancer in the world and the second most common cancer among South African men."( Cronjé, MJ; Joubert, AM; Skerman, NB, 2011)
"Oesophageal cancer is the 7th most common cause of cancer-related death in the developed world and the incidence of oesophageal adenocarcinoma is now the fastest growing of any gastrointestinal cancer."( Ahmed, K; Hanna, GB; Kayani, B; Zacharakis, E, 2011)
"Oesophageal cancer is endemic in some regions of the Islamic Republic of Iran and efforts have made to find factors that play a role in its prognosis."( Alibakhshi, A; Aminian, A; Dashti, H; Ghaderi, H; Hasani, SM; Jahangiri, Y; Karimian, F; Meysamie, A; Mirsharifi, R, 2011)
"Esophageal cancer is the sixth most common cause of cancer-related death worldwide."( Cai, RG; Chen, L; Fan, QX; Hao, XZ; Huang, J; Liu, AN; Sun, Y; Wang, JW, 2011)
"Esophageal cancer is a highly aggressive disease, and improved modalities for its treatment are needed."( Doki, Y; Fujiwara, S; Gnjatic, S; Hatazawa, J; Kanto, T; Kawabata, R; Kawada, J; Kurokawa, Y; Miyata, H; Mori, M; Nakajima, K; Nakamura, Y; Nakayama, E; Nishikawa, H; Sakakibara, M; Sato, E; Sedrak, C; Shimosegawa, E; Takahashi, T; Takiguchi, S; Wada, H; Yamasaki, M, 2012)
"Esophageal cancer is recognized as one of the most refractory pernicious diseases."( Hu, X; Huang, W; Jing, X; Liu, L; Liu, S; Tong, T; Wang, R; Wu, W; Yue, J; Zheng, Y, 2012)
"Esophageal cancer is an intractable disease due to late diagnosis, high incidence of post-surgical locoregional recurrence and frequent distant metastasis."( Dong, Z; Jiang, Y; Li, P; Liu, K; Lu, J; Ma, J; Yang, H; Zhao, J; Zhao, M, 2012)
"Esophageal cancer is the seventh leading cause of cancer death in males in USA, and there is a strong link has been demonstrated between inflammation and esophageal cancer, interleukin (IL)-32 is a recently described pro-inflammatory cytokine characterized by the induction of nuclear factor NF-κB activation, the p38MAPK also plays an important role in key cellular processes related to inflammation and cancer."( Adrienne, J; Al-Amran, FG; Hadi, N; Lee, J; Yousif, NG, 2013)
"Esophageal cancer is a common malignancy with a high mortality rate."( Cai, Y; Hu, M; Jiang, F; Liu, C; Liu, Q; Luo, J; Luo, M; Shi, Q; Song, P; Tang, M; Weng, Y; Yang, D; Zhan, X; Zhang, F; Zhang, Y; Zhou, L; Zuo, G, 2013)
"Esophageal cancer is unusually frequent in Western Kenya, despite the low prevalence of classical risk factors such as heavy drinking and tobacco smoking."( Abnet, CC; Bowyer, P; Collins, R; Dawsey, SM; Dawsey, SP; Freedman, ND; Mwachiro, M; Nieminen, MT; Novak-Frazer, L; Rautemaa, R; Salaspuro, M; White, RE, 2013)
"Oesophageal cancer is a global heath problem."( Chen, X; Chen, XY; Huang, Y; Li, H; Shao, Y; Wen, Y; Wu, S; Xian, L; Yang, C; Yang, S; Zheng, J, 2012)
"Esophageal cancer is a common malignant tumor occurring in human esophageal epithelial tissue."( Huang, GL; Sun, GJ; Wang, SK; Wang, TT; Yang, L; Yang, LG, 2012)
"Esophageal cancer is a disease that is difficult to manage before and after surgery and is associated with a high in-hospital mortality rate despite there being reports of improved outcomes after multidisciplinary treatment."( Akami, T; Matsumura, A; Matsuyama, T; Mugitani, T; Nishibeppu, K; Ogino, S; Shimode, Y; Takemura, M, 2013)
"Esophageal cancer is characterized by increased oxidative stress and the production of 8-hydroxy-2'-deoxyguanosine (8-OHdG), which is one of the main mutagenic modifications of DNA."( He, H; Wang, C; Wang, N; Zhang, L; Zhao, Y, 2014)
"Esophageal cancer is the sixth most common cause of cancer-related deaths worldwide."( Cheung, AL; Guan, XY; Law, S; Li, B; Li, J; Qin, YR; Tsao, SW; Xu, WW; Zhang, LY, 2014)
"Esophageal cancer is one of the most common cancers in North East India."( Das, M; Mahanta, J; Phukan, RK; Saikia, BJ; Sekhon, GS; Sharma, SK, 2015)
"Esophageal cancer is the eighth most common cancer in the world and ranks as the sixth leading cause of cancer-related mortality."( Chen, Z; Gao, Y; He, J; Li, J; Luo, M; Pu, J; Shi, X; Sun, H; Yao, R; Zhou, C; Zhou, F, 2015)
"Esophagectomy for esophageal cancer is one of the most invasive operative procedures."( Kawakubo, H; Kitagawa, Y; Matsuda, S; Miyasho, T; Nakamura, R; Ogura, M; Okamura, A; Saikawa, Y; Takahashi, T; Takeuchi, H; Wada, N, 2015)
"Esophageal cancer is thought to be the most malignant neoplasm due to its biological aggressiveness."( Akutsu, Y; Matsubara, H, 2015)
"Esophageal cancer is a common malignant tumor worldwide with a high incidence rate in China and it is a great threat to human health."( Liu, L; Wang, J; Zuo, J; Zuo, LF, 2015)
"Currently, esophageal cancer is rarely curable, and herein, a paclitaxel or 5-fluorouracil/esophageal stent combination (PTX or 5-FU/stent) was used to provide a new approach to treat this cancer."( Chen, W; Guo, S; Li, J; Liu, J; Shen, Y; Wang, Z; Wu, K, 2015)
"Esophageal cancer is most frequently treated with platinum-based chemoradiotherapy (CRT)."( Emi, M; Hamai, Y; Hihara, J; Kenjo, M; Murakami, Y; Nagata, Y; Okada, M, 2015)
"Esophageal cancers are highly aggressive tumors with poor prognosis despite some recent advances in surgical and radiochemotherapy treatment options."( Ahrens, TD; Boerries, M; Busch, H; Follo, M; Hembach, S; Hoeppner, J; Hopt, UT; Lassmann, S; Ostendorp, J; Timme, S; Werner, M, 2015)
"Esophageal cancer is one of the most frequent causes of cancer-related deaths worldwide."( Ishimine, H; Ito, Y; Kurisaki, A; Seki, Y; Sumitomo, K; Yoshida, Y; Zhou, R, 2016)
"Esophageal cancer is of high prevalence and poor prognosis."( Dong, W; Li, J; Liao, F; Wang, J; Wu, D; Zhang, J, 2016)
"Esophageal cancer is a major global health burden with a strong host-environment interaction component and epigenomics underpinnings that remain to be elucidated further."( Borthakar, BB; Chattopadhyay, I; Kapur, S; Kataki, AC; Mahanta, J; Phukan, RK; Rai, AK; Saxena, S; Sharma, J; Singh, LC; Singh, V; Vasudevan, M, 2015)
"Esophageal cancer is ranked as the eighth most common cancer and the sixth leading cause of cancer deaths worldwide."( Cal, S; Dai, W; Ip, JC; Ko, JM; Lung, ML; Ng, HY; Yu, VZ, 2016)
"Oesophageal cancer is a highly aggressive disease with about 50% of patients presenting with advanced or metastatic disease at initial diagnosis."( Bai, L; Cheng, Z; Dai, G; Han, Z; Liang, P; Liu, F; Tan, S; Yu, J; Yu, X; Zhou, F, 2016)
"Esophageal cancer is one of the most common cancers worldwide, and the incidence and mortality is increasing rapidly in recent years in China, but the underlying mechanisms are largely unclear."( Bao, Y; Chen, Z; Dong, H; Guo, Y; Li, K; Shen, K; Wang, Q; Yang, W; Yang, Y; Zhang, H, 2016)
"Esophageal cancer is one of the least studied and deadliest cancers worldwide with a poor prognosis due to limited options for treatment."( Bode, AM; Chen, H; Dong, Z; Jiang, Y; Li, H; Li, W; Liu, K; Ma, WY; Oi, N; Reddy, K; Saleem, M; Sheng, Y; Wu, Q; Yao, K; Zhang, Y, 2016)
"Esophageal cancer is one of the leading cause of cancer mortality in the world."( Fan, L; He, Z; Hu, X; Jin, Z; Kang, Q; Kong, X; Li, Y; Liao, C; Liu, L; Wang, Y; Wu, H; Wu, X; Xiao, X; Xu, H; Zeng, Y; Zhang, J; Zheng, K, 2016)
"Esophageal cancer is the fourth most common gastrointestinal cancer, it generally has a poor prognosis and novel strategies are required for prevention and treatment."( Hou, L; Wu, K; Yang, L; Yang, P; Zhang, L; Zhao, J, 2016)
"Esophageal cancer is a deadly disease in the esophagus with a poor prognosis."( Fu, S; He, Q; Zhang, Z; Zheng, Z, 2017)
"Esophageal cancer is one of the most aggressive tumor types because of its invasiveness and metastatic potential."( Fushida, S; Harada, S; Hayashi, H; Kinoshita, J; Makino, I; Miyashita, T; Nakanuma, S; Nakayama, A; Ninomiya, I; Ohta, T; Okamoto, K; Oyama, K; Sakai, S; Tajima, H; Takamura, H; Tsukada, T, 2016)
"Esophageal cancer is one of the top leading causes of cancer-related deaths in Malaysia."( Norsa'adah, B; Siti-Azrin, AH; Wan-Nor-Asyikeen, WA, 2016)
"Esophageal cancer is one of the common malignancies worldwide, particularly in eastern African and Asian countries including Japan."( Chen, N; Horii, A; Saiki, Y; Sumarpo, A; Sunamura, M; Wang, R, 2016)
"Esophageal cancer is an aggressive tumor and is the sixth leading cause of cancer death worldwide."( Brandão, CA; Cappellari, AR; Coutinho-Silva, R; da Silva, VD; de Marchi, FO; Gehring, MP; Lopes, TG; Moreira-Souza, ACA; Morrone, FB; Paccez, JD; Pinto, LFR; Santos, AA; Savio, LEB; Zaparte, A; Zerbini, LF, 2017)
"Esophageal cancer is the eighth most common cancer worldwide."( Chen, Y; Hao, D; He, C; Liu, J; Wang, J; Wang, W; Wu, X; Xing, W; Yang, Y, 2017)
"Esophageal cancer is one of the most common type of malignancies."( Dong, Y; He, Q; Liu, Y; Wang, H; Zhou, J, 2017)
"Oesophageal cancer is one of the most common malignancies worldwide,and oesophageal squamous cell carcinoma (ESCC) is the predominant histological type both globally and in China."( Feng, X; Gao, Y; He, J; Li, Z; Shao, F; Shi, S; Wang, C; Yang, X, 2017)
"Esophageal cancer is a common gastrointestinal cancer, with a very high mortality rate in patients with metastasis."( Hu, Y; Li, J; Li, X; Ma, J; Sun, D; Tao, H; Wang, L; Zhang, G, 2018)
"As oesophageal cancer is one of the most aggressive gastrointestinal cancers, we aimed to clarify the effect of Nrf2 on metabolic reprogramming in oesophageal cancer."( Baba, H; Baba, Y; Ishimoto, T; Iwatsuki, M; Kitano, Y; Miyake, K; Nakagawa, S; Nakao, M; Watanabe, M; Yamashita, YI; Yoshida, N, 2018)
"Esophageal cancer is a common malignant tumor worldwide."( Du, X; Li, M; Liu, K; Sun, Q; Wang, L; Wang, Y; Wu, J; Zang, W; Zhao, G, 2018)
"Esophageal cancer is the 8th most common cancers worldwide and the 6th most common cause of death among cancers."( Chen, G; Kang, X; Liu, TD; Zhang, JX; Zheng, BZ, 2018)
"Esophageal cancer is associated with a high mortality rate and easy metastasis."( Chen, YJ; Huang, PI; Liu, YK; Liu, YM; Tsai, TH, 2018)
"Esophageal cancer is one of the worst malignant digestive neoplasms with poor treatment outcomes."( Liu, F; Song, Y; Wang, W; Xing, D, 2018)
"Esophageal cancer is one of the most common cancers in the world."( Chen, T; Dong, X; Li, Y; Ma, H; Meng, X; Qi, D; Su, J; Wang, W; Yang, L; Zhang, X, 2018)
"Esophageal cancer is one of the common causes of cancer mortality in the world."( Feng, Y; Jia, X; Li, N; Lu, F; Xu, M; Yang, CS; Yang, H; Zhang, Q, 2018)
"Esophageal cancer is the eighth most prevalent cancer and has high mortality in our society."( Fang, M; Hua, P; Liu, T; Lu, Z; Wu, M; Zhang, G; Zhang, Y, 2018)
"Esophageal cancer is a common gastrointestinal cancer."( Feng, X; Liu, Q; Qu, F; Shi, Y; Wang, P; Wang, S; Wang, X; Wu, L; Zhang, B; Zhang, K, 2018)
"Esophageal cancer is a common malignant tumor with an increasing trend during the past three decades."( Azizian, M; Derakhshani, M; Ghasemi, F; Hedayt, P; Hesari, A; Mahinparvar, N; Mirzaei, H; Nesaei, A; Sanaei, S; Sheikhi, A, 2019)
"Esophageal cancer is one of the leading causes of cancer death in the male population of Eastern Asia."( Chen, LH; Chuang, EY; Hsieh, YC; Lai, LC; Lee, JM; Lin, WC; Tsai, MH; Yang, PW, 2019)
"Esophageal cancer is a very deadly disease, killing more than 15,000 people in the United States annually."( Kang, Y, 2019)
"Esophageal cancer is one of the most common malignant tumors, characterized by early metastasis and high degree of malignancy."( Chai, T; Chen, S; Kang, M; Lin, J; Lin, W; Lin, Y; Shen, Z; Zhang, P; Zhang, Z, 2019)
"Esophageal cancer is one of the most common cancers around the world, and it has high incidence and mortality rates."( Jiao, GH; Qiu, ZH; Zhang, HH; Zhang, WW, 2019)
"Esophageal cancer is prevalent in Cixian, China, but the etiology of this disease remains largely unknown."( Elzawahry, A; He, Y; Hosoda, F; Inoue, M; Ishino, K; Kato, M; Kikuchi, S; Li, D; Lin, Y; Liu, J; Matsuda, T; Matsushima, Y; Meng, F; Nagai, M; Nakagama, H; Nakamura, H; Qiao, Y; Sato, H; Shan, B; Shibata, T; Song, G; Totoki, Y; Totsuka, Y; Wei, W, 2019)
"Esophageal cancer is a common human malignant tumor with high mortality."( He, S; Li, L; Liu, J; Peng, J; Wang, W; Wu, X; Xu, Y; Yu, J; Zhang, J; Zhang, R, 2019)
"Background Esophageal cancer is a very common malignant tumor in China, especially esophageal squamous cell carcinoma (ESCC), but there is currently no effective treatment for patients after first-line chemotherapy failure."( Lei, J; Song, X; Wang, Y; Yu, J; Zhang, C; Zhang, N; Zhang, S; Zhao, J, 2020)
"Esophageal cancer is a prevalent type of cancer worldwide and is ranked sixth among cancer-associated mortalities."( Anasihan, G; Chen, L; Dai, Y; Ha, YNE; Pidayi, M; Wufuer, D, 2020)
"Esophageal cancer is a highly fatal malignant neoplasm, with 2 etiologically different histological types."( Lagergren, J; Ness-Jensen, E; Santoni, G; Wang, QL; Xie, SH, 2020)
"Esophageal cancer is a digestive tract malignancy, ranking sixth among the world's deadliest tumor incidence."( Li, S; Liang, Y; Zhang, L; Zheng, G, 2020)
"Esophageal cancer is an aggressive malignancy, and its current treatment strategies are plagued with high rates of recurrence."( Liu, H; Wei, W; Yao, Y; Yuan, J, 2021)
"Esophageal cancer is increasingly common and carries a poor prognosis."( Bateman, A; Byrne, JP; Grace, BL; Iveson, T; Jackson, A; Kelly, JJ; Noble, F; Pucher, PH; Rahman, SA; Rees, C; Underwood, TJ; Walker, RC, 2020)
"Oesophageal cancer is the 6th most common cause of cancer related death worldwide."( Buckley, AM; Clarke, N; Davern, M; Dunne, MR; Foley, EK; Kennedy, BN; Kennedy, SA; Lysaght, J; MacCarthy, F; Morrissey, ME; Nolan, A; O'Sullivan, J; O'Toole, D; Ravi, N; Reynolds, JV, 2020)
"Esophageal cancer is one of the fatal cancers around the world."( Bai, Y; He, H; Huang, L; Liu, W; Zhang, P, 2020)
"Esophageal cancer is one of the most common cancer with limited therapeutic strategies, thus it is important to develop more effective strategies to against it."( Han, S; Ma, J; Wang, HD; Wang, Y; Wang, Z; Yuan, Q, 2020)
"Oesophageal cancer is one of the most frequent solid malignancies and the leading cause of cancer-related death around the world."( Jiang, HM; Lan, J; Liu, SN; Lv, J; Qi, D; Wu, MD; Xu, JL; Yang, Y; Yuan, YJ; Zhai, J, 2020)
"Esophageal cancer is one of the most frequently occurring malignancies in China, and the incidence of esophageal cancer ranks 8th in the world."( Chen, Y; Wang, Z; Xiang, M, 2021)
"BACKGROUND Esophageal cancer is a common gastrointestinal malignancy in China."( Hu, L; Jiang, X; Kong, Z; Meng, Q; Wang, J; Yu, J; Zhou, M, 2020)
"Esophageal cancer is a disease showing poor prognosis."( Fujiwara, T; Kato, T; Katsura, Y; Kikuchi, S; Matsukawa, A; Narusaka, T; Nishiwaki, N; Noma, K; Ohara, T; Sato, H; Shirakawa, Y; Tazawa, H; Tomono, Y, 2021)
"Oesophageal cancer is categorised among the most fatal cancers across the world with a mortality ranking of sixth position."( Govero, AB; Kukhon, FR; Sanghavi, DK; Yarrarapu, SNS, 2021)
"Esophageal cancer is a malignancy that has a poor prognosis, which is mainly due to patients presenting once the cancer is in the advances stages."( Fatehi Hassanabad, A; Wong, JVS, 2021)
"Esophageal cancer is a malignant tumor of the digestive tract that is difficult to diagnose early."( Li, FR; Xue, XJ; Yu, J, 2021)
"Oesophageal cancer is the seventh most common cancer in the world and adenocarcinoma is the dominant subtype in Western industrialised nations."( Due, SL; Hussey, DJ; Watson, DI, 2021)
"Esophageal cancer is one of the most common malignant tumors of the digestive system, with high incidence and mortality."( Gao, YM; Li, C; Li, MY; Liu, WY; Ma, YQ; Shi, Y; Song, JW; Wang, B; Wang, H, 2022)
"Esophageal cancer is the most common gastrointestinal tumor and is difficult to be eradicated with conventional treatment."( Chen, T; Chen, ZL; Li, MY; Meerovich, G; Mi, L; Soe, TW; Than, NN; Yan, YJ, 2022)
"Esophageal cancer is the seventh most common cancer globally."( Deng, DX; Heng, JH; Huang, HC; Li, EM; Li, RY; Li, ZM; Liao, LD; Lin, W; Xu, HY; Xu, LY; Xu, XE; Zheng, YQ; Zheng, ZY, 2022)
"Esophageal cancer is a relatively rare cancer."( Che, W; Chen, Y; Liang, H; Peng, F; Wu, B; Xie, X, 2022)
"Esophageal cancer is a very deadly disease ranking 8th most common cancer in terms of incidence and the 6th highest in terms of mortality both in the USA and around the world."( Farooq, T; Farooq, Z; Irfan, A; Muddassir, K; Qayyum, MA; Sultan, MH, 2022)
"Esophageal cancer is the sixth leading cause of cancer death worldwide with considerable geographical histological variation There is a paucity of data in esophageal cancer in demographics, histology, and survival among the multi-ethnic Malaysian population."( Lim, RZM; Mahendran, HA, 2022)
"Esophageal cancer is a leading cause of cancer deaths worldwide, with an increasing incidence in recent decades."( Gibson, MK; Weidenbaum, C, 2022)
"Esophageal cancer is one of the most common malignancies which induces cancer-related death."( Gong, L; Hu, Y; Li, Z; Song, Z, 2022)
"Esophageal cancer is the most prevalent digestive system tumor."( Cheng, C; Li, T; Liu, Y; Lu, H; Mao, Q; Peng, C; Shen, B; Shi, M; Xiao, T; Yang, A, 2022)
"Esophageal cancer is one of the leading causes of cancer death and the seventh most prevalent cancer worldwide."( Jafari, SM; Joshaghani, H; Sheikh Arabi, M; Younesian, O, 2023)
"Esophageal cancer is a lethal disease that frequently occurs in developing countries, the incidence of which could be declined by drinking EGCG-enriched drinks or food."( Chen, Z; Lin, X; Teng, Q; Wei, Y; Wu, F; Zheng, Y; Zhou, F; Zhu, H, 2022)
"Esophageal cancer is a lethal disease that frequently occurs in developing countries, the incidence of which could be declined by drinking EGCG-enriched drinks or food."( Chen, Z; Lin, X; Teng, Q; Wei, Y; Wu, F; Zheng, Y; Zhou, F; Zhu, H, 2022)
"Esophageal cancer is a highly aggressive malignancy with a low response to standard anti-cancer therapies."( Jing, X; Wang, T; Zhang, F; Zhao, W, 2023)
"Esophageal cancer is a common digestive tract malignant tumor."( Li, S; Liang, Y, 2023)
"Esophageal cancer is one of the major life-threatening diseases in the world."( Han, Y; Li, B; Li, H; Meng, W, 2023)
"Esophageal cancer is the seventh most common cancer in the world."( Deng, DX; Heng, JH; Li, EM; Liao, LD; Lin, W; Liu, LX; Xu, LY; Xu, XE; Zhao, H; Zheng, ZY, 2023)
"Surgery for esophageal cancer is associated with high mortality and morbidity, especially in low and middle-income countries."( Arora, A; Khurana, G; Ramakrishnan, P; Saini, S, 2023)
"Esophageal cancer is a highly malignant disease with poor prognosis."( Gao, Y; Sheng, G; Wang, T; Wu, H; Wu, J, 2023)
"Esophageal cancer is the seventh most common malignancy worldwide and the sixth leading cause of cancer mortality with an overall survival rate of <20%."( Hsieh, YC; Wu, JS, 2023)

Context

ExcerptReference
"Esophageal cancer has a low cure rate, and the possibility for increased survival can be enhanced primarily through early detection."( Hix, WR; Wilson, WR, 1987)
"Esophageal cancer has been conventionally treated with surgery and radiotherapy for many years."( Advani, SH; Badwe, RA; Desai, PB; Deshpande, RK; Dinshaw, KA; Saikia, T; Santhi Swaroop, V; Sharma, S; Vyas, JJ, 1989)
"Human esophageal cancer has been epidemiologically associated with riboflavin deficiency, but the precise role of riboflavin in this tumor remains to be defined."( Rivlin, RS, 1986)
"Oesophageal cancer has a high incidence rate in India and both males and females are affected almost equally."( Jussawalla, DJ, 1981)
"Treatment of esophageal cancer has been primarily palliative."( Bates, DM; Clyde, JC; Garcia, JM; Girvin, GW; Lin, PH; Matsumoto, GH, 1995)
"Endemic cancer of the esophagus has shown a positive association with the consumption of maize meal."( Sammon, AM, 1999)
"Advanced thoracic esophageal cancer has a poor prognosis despite advances in surgery, such as three-field lymph node dissection."( Honnma, S; Kohashi, S; Kondo, M; Kudo, T; Maeda, Y; Sato, Y; Shimokuni, T; Shinohara, T; Takahashi, S; Todo, S, 2004)
"Esophageal cancer has been reported to be frequently associated with cancer of the head and neck."( Aikou, T; Ishigami, S; Matsumoto, M; Nakashima, H; Natsugoe, S; Okumura, H; Takao, S; Takatori, H, 2004)
"Esophageal cancer has a poor prognosis."( Fujitani, K; Hirao, M; Tsujinaka, T, 2005)
"As patients with oesophageal cancer have a high incidence of co-morbidities including cardiac problems, the aim of this paper was to quantify the extent of cardiac radiation and discuss the influence of beam arrangement to reduce this."( Cominos, M; Cornes, P; Henrys, A; Mosleh-Shirazi, MA; Tait, D, 2005)
"Human esophageal cancers have been shown to express high levels of epidermal growth factor receptor (EGFR) and a relationship between high EGFR expression and local advance, the number of lymph node metastases, life expectancy, and sensitivity to chemo-radiotherapy has been demonstrated."( Doihara, H; Hara, F; Ishibe, Y; Oota, T; Shien, T; Shimizu, N; Taira, N; Takahashi, H; Yoshitomi, S, 2006)
"Since esophageal cancer has often metastasized at the time of diagnosis, current treatment modalities offer poor survival and cure rates."( Chen, T; Stoner, GD; Wang, LS, 2007)
"Cancer of the esophagus has a poor long-term prognosis and a high peri-operative morbidity in which pulmonary complications play a major role."( Hofer, CK; Metzger, U; Seifert, B; Zingg, U; Zollinger, A, 2007)
"Esophageal cancer has been associated with tobacco and alcohol consumption, gastric reflux, exposure to nitrosamines from food or other environmental sources, and diets lacking folate."( Gao, CM; Hasan, Q; Langevin, SM; Lin, D; Matsuo, K; Stolzenberg-Solomon, RZ; Taioli, E; Takezaki, T; Vasavi, M, 2009)
"The incidence of esophageal cancer has steadily increased over the past three decades."( Alavi, A; Basu, S; Heidari, P; Salavati, A, 2009)
"Esophageal cancer has become one of the most common cancers to occur in the world, and the incidence in South Africa is high, especially within the black male population."( Abrahamse, H; Cronjé, MJ; Kresfelder, TL, 2009)
"Esophageal cancer has diverse incidence worldwide, and genetic/environmental risk factors are supposed to be responsible for it."( Malik, MA; Mittal, B; Upadhyay, R; Zargar, SA, 2010)
"Esophageal cancer has been increasing in incidence for the last several decades."( Brown, RK; Frey, KA; Hansen, N; Khan, A; Orringer, M, 2010)
"Gastroesophageal cancer has a rapidly increasing incidence worldwide and reliable biomarkers are urgently required to facilitate earlier diagnosis and improve survival."( Antonowicz, S; Hanna, GB; Kumar, S; Markar, SR; Wiggins, T, 2015)
"Esophageal cancer has a poor prognosis partially due to its low sensitivity to chemotherapy agents, and the development of new therapeutic agents is urgently needed."( Chen, Z; Gao, Y; He, J; Li, J; Luo, M; Pu, J; Shi, X; Sun, H; Yao, R; Zhou, C; Zhou, F, 2015)
"Esophageal cancer has a high mortality rate, and its multimodality treatment is often associated with significant rates of severe toxicity."( Bowen, JM; Game, PA; Hussey, DJ; Irvine, T; Karapetis, CS; Keefe, DM; Kristaly, K; Smith, L; Tan, H; Thompson, SK; Tsykin, A; Watson, DI; White, I, 2015)
"Esophageal cancer has a persistently low 5-year survival rate and has recently been classified as a cancer of unmet need by Cancer Research UK."( Boumelha, AJ; Dobrynin, G; Hammond, EM; Hawkins, MA; Ient, J; Leslie, RE; Leszczynska, KB; Maughan, T; Mukherjee, S; Senra, JM, 2016)
"Esophageal cancer has a 5 year survival rate of ∼20%."( Burdick, MM; Carlson, GE; Drozek, DS; Goetz, DJ; Noori, MS; Streator, ES, 2018)
"Esophageal cancer has recent shown a higher incidence but lower 5-year survival rate after normal clinical treatment in China."( Bai, M; Dong, Y; Han, S; Ma, J; Sun, X; Zhou, C, 2020)
"Esophageal cancer has a poor prognosis."( Chen, LC; Chen, Y; Chen, YH; Chuang, KH; Lai, HH; Li, SH; Lo, CM; Lu, HI, 2021)
"Human esophageal cancer has a global impact on human health due to its high incidence and mortality."( Dong, Z; Jiang, Y; Kim, MO; Laster, KV; Li, X; Liu, K; Lu, X; Wang, D; Wei, Y; Yang, N; Yu, Y; Yuan, B; Zhao, L, 2022)
"Esophageal cancer has always been associated with poor prognosis and a low five-year survival rate."( Chen, Y; Ge, C; He, R; Jin, Y; Wu, H; Yang, Y; Zhou, B; Zou, X, 2022)
"Esophageal cancer has one of the poorest prognoses among all cancer types, due to the propensity for an early spread through the lymphatics and the difficulty to perform surgical treatment."( Kawakubo, H; Kitagawa, Y; Matsuda, S; Takeuchi, M; Tsuji, T, 2023)

Treatment

ExcerptReference
"Treatment of the human esophageal cancer cell line EC8712 with retinoic acid (RA) stopped the cell growth significantly and gave rise to terminal differentiation of the cells characterized by increased expression of involucrin gene."( Cai, Y; Feng, L; Fu, M; Tian, Y; Wang, XQ; Wang, ZH; Wu, M, 1992)
"The records of patients with esophageal cancer who were treated with a combined modality therapy were reviewed to determine the effects of simultaneously administered chemotherapy and radiotherapy (RT) at sites of recurrence and the relationship between treatment outcome and clinicopathologic variables."( Denham, JW; Devitt, PG; Gill, PG; Jamieson, GG; Olweny, C; Yeoh, E, 1992)
"Three cloned esophageal cancer cell lines, Cu3, Cu4 and Cu6, were established from Eca109 cancer cells, and four cloned esophageal cancer cell lines, Ct1, Ct2, Ct5 and Ct7, were established from Eca109 cancer cells after hematoporphyrin photodynamic therapy."( Ning, A, 1991)
"On the other hand, a clinical case of esophageal cancer with an estrogen receptor showed a growth inhibition of primary carcinoma cells by estradiol treatment."( Kido, Y; Matsuoka, H; Mitsudomi, T; Shirabe, K; Sugimachi, K; Ueo, H; Yano, K, 1990)
"The advantages of chemoradiotherapy in esophageal cancer could be summarized as follows: higher response rate (60-80%), higher proportion of complete responses (up to 45%), longer remission duration, lower radiation dosage (3,200-4,000 cGy) and consequently better tolerance of treatment (less morbidity)."( Kolarić, K, 1985)
"A series of 25 patients with advanced esophageal cancer treated from Mar."( Wang, ZY, 1986)
"Thirty patients with cancer of the esophagus were treated with multimodality therapy."( Chalaoui, J; Duprat, G; Duranceau, A; Robidoux, A; Sylvestre, J, 1987)
"Thirty-two cases of esophageal cancer were treated with thermochemotherapy from August 1984 to June 1985."( Hou, BS; Li, DJ, 1987)
"Thirty-four cases of esophageal cancer were treated by radiation combined with chemotherapy and hyperthermia (triple therapy) from September 1985 to January 1986."( Hou, BS; Li, DJ; Xiong, QB, 1989)
"Thirty-five consecutive esophageal cancer patients were treated by a combination regimen COPU (CTX 600-800 mg/m2, IV, on days 1, 8, 15 at 8 PM; VCR 1."( Qi, WB, 1989)
"Eleven patients with advanced oesophageal cancer were treated with carboplatin."( Mannell, A; Winters, Z, 1989)
"Three patients with esophageal cancer, who were treated by FT+BrdU+radiation with good results, are reported."( Hanyu, F; Ide, H; Kobayashi, S; Muto, H; Nakagawa, M; Shimamura, Y; Takasaki, K; Tanaka, S; Yamada, A; Yamamoto, M, 1987)
"Altogether 46 patients with esophageal cancer and stomach cancer with esophageal involvement were investigated before therapy."( Okulov, LV; Piperkova, EN; Shishkina, VV, 1988)
"The results of gamma-beam therapy of esophageal cancer leave much to be desired."( Azhigaliev, NA; Kusherbaev, SK; Sadykov, SS, 1988)
"The induction of esophageal cancer was enhanced by TPA given in drinking water after AMN administration; i."( Kuwano, H; Matsufuji, H; Mori, M; Sugimachi, K; Ueo, H, 1987)
"Fifty-seven patients with esophageal cancer were treated with curative intent between January 1979 and June 1985."( Bae, Y; Burdakin, J; Jacobsen, G; Lewis, J; Richmond, J; Seydel, HG, 1987)
"Twenty-four patients with squamous cell cancer of the esophagus were entered into a treatment protocol consisting of preoperative chemotherapy (CT), surgical resection (SR), and possible postoperative CT or radiation therapy (RT) beginning August 1981."( Carey, RW; Choi, NC; Grillo, H; Hilgenberg, AD; Mathisen, DJ; Wilkins, EW, 1986)
"For surgical treatment of esophageal cancer, the importance of evaluating lymph node metastasis and the lymph flow of the esophagus can not be overemphasized."( Aikou, T; Baba, M; Kajisa, T; Kuroshima, K; Natugoe, S; Tanabe, G; Yoshinaka, H, 1986)
"The incidence of esophageal cancer in oral administration group was 42."( Kobayashi, K, 1985)
"Ten patients with squamous cancer of the esophagus were treated with an outpatient regimen combining cis-diamminedichloroplatinum (II), methotrexate and bleomycin."( Greenwald, E; Kaplan, BH; Vogl, SE, 1981)
"Eight patients with esophageal cancer were treated by a new treatment schedule consisting of low dose irradiation, crescendo cisplatin and bleomycin polyacrylate pasta."( Lim, I; Mishina, H; Ogasawara, T; Okuyama, S; Taima, T; Yamagata, R; Yamamoto, K, 1983)
"Indications of surgical therapy for esophageal cancer patients with metastasis are limited."( Kasai, M; Nishihira, T, 1983)
"Twenty-one patients with squamous cell cancer of the esophagus were entered into a pilot clinical trial using preoperative chemotherapy (5-fluorouracil and cis-platinum) and radiation with the intent of improving cure rate and survival."( Dindogru, A; Kinzie, J; Leichman, L; MacKenzie, G; Seydel, HG; Shell, J; Steiger, Z; Toben, S, 1984)
"In the patients with esophageal cancer after MZ administration via the gastrostoma, the nature and time course of drug accumulation in the blood was identical, however accumulation maximum was lower and reached 219 +/- 25 micrograms/ml."( Dar'ialova, SL; Kiseleva, ES; Poliakov, PIu; Zel'vin, BM; Zimina, ES, 1984)
"Twelve patients with untreated cancer of the esophagus and 14 control subjects matched for age, smoking, and alcohol consumption were tested for taste thresholds."( Booth, P; Kamath, S; Kohrs, MB; Lad, TE; McGuire, WP, 1983)
"We report a case of double cancer of esophagus and stomach treated with 5-fluorouracil and consecutive low-dose cisplatin."( Akiyama, S; Hibi, K; Ito, K; Kasai, Y; Kondo, K; Nonami, T; Takagi, H, 1995)
"Conventional treatment of esophageal cancer with surgery or radiation alone has afforded few long-term survivors."( Chang, HS; Choi, EK; Kim, SB; Kim, SH; Kim, SW; Lee, JS; Lee, JW; Lee, KH; Song, HY; Suh, CW, 1995)
"Sixteen inoperable esophageal cancer patients, including six over 80 years of age, were given combined chemoradiation therapy."( Ashizawa, A; Katsuta, T; Kinoshita, T; Kobayashi, M; Miyahara, M; Saito, T; Shigemitsu, Y; Shimoda, K, 1993)
"Thirty-five patients with oesophageal cancer were treated with external beam irradiation (50-60 Gy) followed by a boost-dose of 15-20 Gy by means of low dose rate intraluminal brachytherapy."( Caspers, RJ; Davelaar, J; Griffioen, G; Leer, JW; Sewsingh, EN; Welvaart, K; Zwinderman, AH, 1993)
"Ten patients with inoperable advanced esophageal cancer were treated with endoscopic local injection of PEP-CH combined with radiation using 60Co."( Hagiwara, A; Kojima, O; Oyama, T; Ozaki, K; Sakakibara, T; Sakakura, C; Sasaki, S; Shimotsuma, M; Takahashi, T; Tsujimoto, H, 1993)
"Neoadjuvant therapy for cancer of the esophagus and cardia results in good tumor response."( Drinkard, LC; Ferguson, MK; Haraf, DJ; Hoffman, PC; Reeder, LB; Vokes, EE, 1995)
"Preoperative chemotherapy for esophageal cancer was performed and the toxic effects, post-operative complications, histological effects and survival time were evaluated."( Abe, T; Fujita, M; Hosokawa, M; Ishihara, K; Kusano, M; Miura, T; Ohara, M; Okayasu, T; Tanabe, Y; Yamazaki, S, 1995)
"Treatment of esophageal cancer has been primarily palliative."( Bates, DM; Clyde, JC; Garcia, JM; Girvin, GW; Lin, PH; Matsumoto, GH, 1995)
"In one case with esophageal cancer, clinical symptoms persisted after the start of antimicrobial chemotherapy and the patient died 10 days later associated with complications of esophageal cancer."( Kikuchi, K; Kobayashi, M; Okada, S; Oomori, Y; Shimizu, K; Tomonaga, O; Totsuka, K; Yoshida, K, 1994)
"An advanced esophageal cancer patient with multiple liver metastases was treated with a combination of CDDP, 5-FU and THP-ADM."( Anai, H; Ichiyoshi, Y; Matsuzaki, K; Minamisono, Y; Miura, O; Nagasaki, S; Toda, T, 1993)
"Surgical treatment of cancer of the esophagus is influenced by two issues: use of surgical resection within a multimodality treatment approach and selection of the correct surgical approach."( DeCamp, MM; Sugarbaker, DJ, 1993)
"Current and proposed trials in esophageal cancer have changed their focus accordingly to meet this new treatment challenge."( Coia, LR, 1993)
"Four patients with esophageal cancer and one patient with gastric cancer were treated with high-dose drip infusions of DDP to a total daily dose of 70-80 mg/m2."( Ando, N; Hoshiya, Y; Kitajima, M; Kubota, T; Kumai, K; Kurihara, N; Otani, Y, 1996)
"We conclude that inoperable esophageal cancer can be treated successfully by radiotherapy with a curative intent."( Calais, G; Chauvet, B; Geara, F; Le Floch, O; Reynaud-Bougnoux, A, 1990)
"From January 1990 to April 1993, 60 oesophageal cancer patients were enrolled in a protocol of non-surgical treatment that consisted of induction chemotherapy followed by concurrent chemoradiotherapy."( Aman, E; Barugel, M; Blajman, C; Carraro, S; Fiorini, A; Giglio, R; Gonzalez, G; Jarentchuk, A; Kneitschel, R; Milano, C; Nadal, J; Navigante, A; Pennella, E; Roca, E; Santarelli, MT; Sardi, M, 1996)
"Since 1984, 373 patients with oesophageal cancer have been treated on three prospective, but unrandomised, protocols involving radiation with concurrent cisplatin and infusional fluorouracil."( Burmeister, BH; Denham, JW; Hamilton, CS; Joseph, DJ; Lamb, DS; O'Brien, P; Spry, NA; Walker, QJ; Yeoh, E, 1996)
"In patients with esophageal cancer, combined chemotherapy is usually given as a part of multimodality treatment and therefore undesirable toxicity should be diminished."( Eguchi, R; Hayashi, K; Ide, H; Nakamura, T, 1996)
"Twenty-five patients with esophageal cancer were treated in a phase I pilot protocol consisting of initial esophagectomy with gastroesophagostomy and subsequent combined chemotherapy and radiation."( Doolas, A; Ebie, N; Griem, K; Hartsell, W; Kang, HJ; Millikan, K; Murthy, AK; Recine, DC; Taylor, S, 1997)
"One case of esophageal cancer, 7 of gastric cancer, 2 of colorectal cancer, 1 of carcinomatous peritonitis from unknown origin, and 1 of hepatocellular carcinoma, were treated by daily low-dose cisplatin combined with 5-FU or tegafur, and their ECOG Performance Status Score (PS), number of lymphocytes, and CD3 zeta chain expression of peripheral blood lymphocytes were studied to compare with the effects of treatment."( Hada, M; Horigome, M; Iida, B; Koshizuka, K; Mutoh, S; Nakagomi, H; Tada, Y; Takano, K; Watanabe, K; Yamadera, Y, 1997)
"In patients with squamous-cell esophageal cancer, preoperative chemoradiotherapy did not improve overall survival, but it did prolong disease-free survival and survival free of local disease."( Bosset, JF; Elias, D; Gignoux, M; Lozach, P; Mantion, G; Mercier, M; Ollier, JC; Pavy, JJ; Sahmoud, T; Tiret, E; Triboulet, JP, 1997)
"Trimodality treatment for esophageal cancer may provide long-term survival in some patients regardless of their pCR status."( Bernard, SA; Detterbeck, FC; Egan, TM; Jones, DR; Parker, LA; Tepper, JE, 1997)
"In the management of esophageal cancer, endoscopy has evolved from a tool used to provide biopsy confirmation of suspected tumor to an integral part of the staging and ongoing treatment of patients."( Kimmey, MB; Ponec, RJ, 1997)
"Salvage surgery for the T4 esophageal cancer following downstaging by neoadjuvant chemo-radiotherapy has become to be available."( Ando, N; Kitagawa, Y; Kitajima, M; Ozawa, S; Takeuchi, H, 1997)
"Forty patients with esophageal cancer were treated in a phase I and II trial of induction chemotherapy (cisplatin, 5-fluorouracil, and paclitaxel) at three dosage levels (75, 125, and 100 mg/m2) and concurrent hyperfractionated radiotherapy (45 Gy to the mediastinum, 58."( Carey, RW; Choi, NC; Grillo, HC; Grossbard, ML; Lynch, TJ; Mathisen, DJ; Moncure, AC; Wain, JC; Wright, CD, 1997)
"The treatment of patients with thoracic esophageal cancer invading adjacent organs is controversial."( Kobori, O; Muto, T; Nagawa, H; Seto, Y, 1997)
"Patients with localized esophageal cancer also received radiation therapy beginning on day 1 (1."( Greco, FA; Hainsworth, JD; Meluch, AA, 1997)
"Two of five patients with esophageal cancer responded (partial response) to this treatment."( Gadgeel, S; Hussain, M; Philip, PA; Shields, A; Zalupski, MM, 1997)
"Pretreatment of esophageal cancer cells with 9-cis-retinoic acid did not substantially potentiate flavopiridol activity in these cell lines."( Altorki, NK; Chen, GA; Matthews, W; Mixon, A; Schrump, DS, 1998)
"A series of patients with esophageal cancer was treated with chemotherapeutic regimens of the new antitumor platinum preparation nedaplatin plus 5-FU in combination with radiation therapy, and the therapeutic responses, side effects, and complications were clinically assessed."( Asai, A; Hioki, K; Michiura, T; Mori, T; Motohiro, T; Yamanaka, H, 1998)
"Advanced gastric, colon and esophageal cancers (n = 21) were treated with 5-FU (250 mg) modulated by CDDP (5 mg)."( Hisano, H; Kida, H; Nomura, M; Shibasaki, S; Shinkai, K; Yano, H, 1999)
"We describe a case of advanced esophageal cancer treated successfully by chemotherapy with nedaplatin alone."( Fukuda, S; Hizawa, Y; Munakata, A; Saitoh, S; Sakata, Y; Satoh, T; Takasugi, T; Tamura, Y; Tohno, H; Tsushima, K; Yamada, Y, 1999)
"The cases with esophageal cancer, stomach cancer, pancreatic cancer, hepatocellular carcinoma or colonic cancer co-existing with their inoperable lesion(s) were considered in this chemotherapy."( Denno, R; Hirata, K; Kimura, H; Mukaiya, M; Oikawa, I; Sasaki, K; Shirasaka, T; Tsuji, A; Yamamitsu, S, 1999)
"Sixty-four patients with advanced oesophageal cancer were treated with a cisplatin dose of 60 mg m(-2) and increasing doses of paclitaxel from 100 mg m(-2) up to 200 mg m(-2) both administered over 3 h for a maximum of six cycles in patients with stable disease or eight cycles in responding patients."( Kerkhofs, L; Kok, TC; Siersema, PD; Splinter, TA; Tilanus, HW; van der Gaast, A, 1999)
"The treatment of upper thoracic esophageal cancer remains challenging, and combined treatment is necessary to improve the outcome."( Doki, Y; Inoue, M; Monden, M; Shiozaki, H; Tsujinaka, T; Yamamoto, M; Yano, M, 1999)
"Three cases of prominent-type advanced esophageal cancer were treated with chemoradiation therapy using a 5-FU analog and low dose CDDP."( Fukao, K; Kawai, Y; Kawamoto, T; Koike, N; Maruyama, T; Monoi, H; Ohara, K; Shimizu, W; Todoroki, T; Yamamoto, Y; Yoshida, S, 1999)
"A 63-year-old male with an esophageal cancer invading the bronchus was treated with radiation therapy (70 Gy) from November 1995, resulting in the disappearance of the lesion."( Hada, T; Kobayashi, I; Kohno, S; Matai, K; Oda, Y; Ohmori, H; Sasaya, K; Yamazaki, Y, 1999)
"It seems likely that survival in oesophageal cancer is improved by multimodal therapy encompassing radiotherapy, chemotherapy and surgery."( Frey, E; Schefer, H; Thum, P, 1999)
"Fifty-three patients with localized esophageal cancer received concurrent chemoradiotherapy followed by brachytherapy."( Dokiya, T; Oki, Y; Yorozu, A, 1999)
"Local control of esophageal cancer is excellent following neoadjuvant chemotherapy and radiation therapy."( Adelstein, DJ; Becker, M; Chidel, MA; Kupelian, PA; Rice, TW; Suh, JH, 1999)
"Multimodality therapy of esophageal cancer has been evaluated in several clinical trials, with positive results in terms of improved survival compared with single-modality therapy."( Wright, CD, 1999)
"A 64-year-old man with unresectable esophageal cancer (A3, N1, M0) was treated with concurrent chemoradiotherapy."( Inoue, H; Ise, H; Matsumoto, G; Matsuo, S; Suzuki, N, 1999)
"The early detection of superficial esophageal cancer and dysplasia in asymptomatic patients with HNC, after successfully treating the primary cancer, may provide an effective cure."( Altemani, A; Brandalise, N; Lage, HT; Martins, AS; Molina, G; Scanavini, RC; Tincani, AJ; Valério, JB, 2000)
"It is possible to cure oesophageal cancer with chemo-radiotherapy and selective oesophagectomy, and achieve organ preservation in the majority of long term survivors."( Lim, JT; Wilson, KS, 2000)
"We examined esophageal cancers from 138 patients to investigate whether mutational status of p53 could be correlated either with prognosis or with response to chemotherapy or radiation."( Furukawa, Y; Hirata, K; Kihara, C; Kimura, Y; Nakamura, Y; Seki, T; van Schaardenburgh, P; Yamana, H, 2000)
"Six nonoperated esophageal cancer patients were treated by daily concurrent CRT, which consisted of continuous 5-fluorouracil administration with leucovorin, combined with a low dose of daily cisplatin administration before each fraction of radiation."( Aoki, F; Kaminishi, M; Murakami, T; Shimoyama, S; Toyoda, K, 2000)
"Fifty-seven patients operated for esophageal cancer in 1997 and 1998 were treated with perioperative steroid therapy."( Arima, M; Funami, Y; Gunji, Y; Hayashi, H; Kobayashi, S; Matsubara, H; Miyazawa, Y; Nabeya, Y; Ochiai, T; Okazumi, S; Shimada, H; Suzuki, T; Takeda, A, 2000)
"Fifty-six patients with thoracic esophageal cancer infiltrating neighboring organs, but with no hematogeneous metastasis, were given preoperative concurrent chemotherapy (5-fluorouracil and cisplatin) and radiation (40 Gy) therapy."( Doki, Y; Fujiwara, Y; Inoue, M; Monden, M; Shiozaki, H; Tsujinaka, T; Yano, M, 2000)
"Because esophageal cancer initiation by NMBA is very rapid in ZD rats, this study determined whether DFMO is effective in preventing esophageal carcinogenesis when administered after the establishment of a carcinogenic environment."( Fong, LY; Magee, PN; Nguyen, VT; Pegg, AE, 2001)
"We analyzed expression profiles of 20 esophageal cancer tissues from patients who were treated with the same adjuvant chemotherapy after removal of tumor by operation, and we attempted to find genes associated with the duration of survival after surgery."( Furukawa, Y; Hirata, K; Kihara, C; Kitahara, O; Nakamura, Y; Ono, K; Takagi, T; Tanaka, T; Tsunoda, T; Yamana, H; Yanagawa, R; Zembutsu, H, 2001)
"We report a case of advanced esophageal cancer, which was treated by chemoradiotherapy combined with surgical treatment."( Fukao, K; Kawamoto, T; Koike, N; Kondo, T; Moon, Y; Nakagawa, Y; Ohara, K; Shimizu, W; Todoroki, T; Yamamoto, Y; Yoshida, S, 2001)
"Since the therapy of advanced oesophageal cancer is unsatisfying, new therapeutic approaches are mandatory."( Barthel, B; Höpfner, M; Kap, H; Maaser, K; Scherübl, H; Sutter, AP; von Lampe, B; Zeitz, M, 2002)
"As a regional chemotherapy after esophageal cancer operation, the injection of CDDP-MS into the mediastinum for targeting of the lymph nodes thus promises to be an effective treatment."( Hamabe, Y; Hyon, SH; Ikuta, H; Kuroda, Y; Nakamura, Y, 2002)
"On the other hand, as esophageal cancer is treated mainly by surgery in Japan, CRT is applied in patients with tumors invading adjacent organs, and a high pathological complete response rate is reported in some neoadjuvant studies."( Hirakawa, K; Kubo, N; Matsumura, Y; Ohira, M; Yamashita, Y; Yamazaki, M, 2002)
"We report a patient with esophageal cancer with concomitant liver metastasis in whom complete response was achieved by chemoradiation therapy."( Hiramoto, J; Murakami, S; Nagayama, K; Nakada, T; Sakabe, S; Tsuruta, Y, 2002)
"From 1991 to 1997, 83 consecutive esophageal cancer patients underwent surgical exploration after completion of two cycles of cisplatin and 5-fluorouracil chemotherapy regimens, either in pulse or in continuous infusion cycles."( Chan, AC; Chung, SC; Griffith, JF; Lam, CC; Lam, YH; Lau, JY; Lee, DW; Leung, SF; Ng, EK, 2002)
"We reviewed salvage surgery cases for esophageal cancer following radical chemoradiotherapy."( Boku, N; Gotohda, N; Nagai, K; Nishimura, M; Ohtsu, A; Yoshida, J, 2002)
"The aim of therapy for advanced esophageal cancer is relief of dysphagia with minimal treatment-related morbidity."( Barr, H; Bown, SG; Dawes, RF; Eysselein, V; Giovannini, M; Harbord, M; Mishra, L; Orenberg, EK; Viens, P, 2002)
"A 77-year-old man with advanced esophageal cancer with tracheal and esophageal obstruction underwent continuous low-dose FP chemotherapy for a total of seven weeks, resulting in a complete response (CR) and disappearance of the esophago-tracheal fistula."( Hasebe, K; Sasaki, S; Takamura, H; Urade, M; Yagi, M, 2002)
"Recently chemoradiotherapy for esophageal cancer has been drawing public attention to the issue of quality of life maintenance for patients."( Endo, T; Hara, T; Hoshikawa, Y; Iino, S; Inaba, H; Kato, N; Kitajima, S; Kobayashi, Y; Koitabashi, Y; Miyazaki, A; Nakagawa, T; Nakaya, S; Ogihara, K; Tsuda, T; Watanabe, Y, 2002)
"The mainstay of curative treatment for oesophageal cancer is currently surgery with neoadjuvant chemotherapy or radiotherapy."( Anderson, MR; Jankowski, JA, 2002)
"Sixty-seven patients with progressive esophageal cancer treated with CRT were included in this study."( Fumoto, S; Mueller, W; Noguchi, T; Shibata, T; Takeno, S; Uchida, Y, 2002)
"The human esophageal cancer xenografts in nude mice treated by boanmycin showed morphological changes of different apoptotic phases."( Tang, H; Yang, XP, 2002)
"Thirteen patients with locally advanced esophageal cancer (T4 cases) and 3 with recurrence of esophageal cancer were treated with radiotherapy (40-70 Gy) and 5-FU combined with cisplatin/nedaplatin concurrently."( Kawasaki, H; Matsuya, H; Morita, T; Morohashi, H; Nakai, M; Sasaki, M; Shibata, S; Yamada, K, 2002)
"Among the gastrointestinal cancers, esophageal cancer is supposed to be relatively sensitive to both radiotherapy and chemotherapy."( Gotoh, M; Kogure, M; Terashima, M, 2002)
"Multimodal treatment of esophageal cancer showed promising results, although not significant, in terms of survival and disease progression for patients achieving a complete pathologic response."( Baccarani, U; Bresadola, F; Bresadola, V; Buffoli, A; Cartei, G; Cedolini, C; Fongione, S; Iop, A; Sacco, C; Signor, M; Terrosu, G; Uzzau, A; Vigevani, E, 2003)
"Treatment of Barrett's esophageal cancer is often conducted in accordance with the principles of treatment of esophageal squamous cell carcinoma, and surgical resection represents the most effective treatment."( Fujiwara, Y; Fukuhara, K; Kaneko, M; Kinoshita, H; Lee, S; Nishizawa, S; Osugi, H; Taguchi, S; Takemura, M; Tanaka, Y, 2003)
"Ninety-two patients with esophageal cancer (65 with adenocarcinoma and 27 with squamous cell carcinoma) were treated in two sequential protocols of preoperative chemoradiotherapy."( Burtness, B; Forastiere, AA; Heath, EI; Heitmiller, R; Kleinberg, L; Knisely, JP; Salem, R; Zahurak, M, 2003)
"Since mucosal (T1a) esophageal cancer is well controlled by endoscopic treatment, chemoradiotherapy (CRTx) is not indicated."( Fujita, H; Hayabuchi, N; Matono, S; Sasahara, H; Shirouzu, K; Sueyoshi, S; Suzuki, G; Tanaka, T; Yamana, H, 2003)
"Specimens of 106 patients with esophageal cancer who had pretreatment Ts/Ls staging were retrospectively studied."( Burrows, W; Eslami, A; Gamliel, Z; Henry, M; Ioffe, O; Jiao, X; Krasna, MJ; Kwong, KF; Refaely, Y; Zeng, Q, 2003)
"No effective treatment for advanced esophageal cancer extending to adjacent organs or associated with distant metastasis is known."( Horiuchi, Y; Indo, T; Iwase, H; Iyo, T; Kaida, S; Kato, E; Kusugami, K; Nakamura, M; Nakarai, K; Shimada, M, 2003)
"Treatment of human esophageal cancer KYSE 510 cells with 5-50 microM of EGCG for 12-144 h caused a concentration- and time-dependent reversal of hypermethylation of p16(INK4a), retinoic acid receptor beta (RARbeta), O(6)-methylguanine methyltransferase (MGMT), and human mutL homologue 1 (hMLH1) genes as determined by the appearance of the unmethylation-specific bands in PCR."( Ai, N; Fang, MZ; Hou, Z; Lu, H; Sun, Y; Wang, Y; Welsh, W; Yang, CS, 2003)
"However, since esophageal cancer can hardly be cured by definitive chemotherapy alone, chemotherapy plays an important role in the multimodality therapy for esophageal cancer."( Nabeya, Y; Ochiai, T, 2003)
"We report a case of esophageal cancer infiltrating the left main bronchus in which radical esophagectomy with clear surgical margins could be performed after preoperative radiochemotherapy."( Fujiwara, Y; Fukuhara, K; Kaneko, M; Kinoshita, H; Lee, S; Nishizawa, S; Osugi, H; Taguchi, S; Takemura, M; Tanaka, Y, 2003)
"Ten patients with recurrent esophageal cancer were treated with the combination of docetaxel 60 mg/m2 (day 1), CDDP 10 mg/body (days 1-5) and 5-FU 500 mg/body (days 1-5) at intervals of 2-3 weeks."( Fujita, H; Matono, S; Sasahara, H; Shirouzu, K; Sueyoshi, S; Tanaka, T; Yamana, H, 2003)
"Patients with metastatic or recurrent esophageal cancer were treated with gemcitabine 1000 mg/m(2) on days 1, 8, and 15, and cisplatin 100 mg/m(2) on day 15."( Abbruzzese, JL; Benedetti, JK; Chansky, K; Macdonald, JS; Pluenneke, RE; Urba, SG; VanVeldhuizen, PJ, 2004)
"Most patients with locally advanced esophageal cancer die from their disease, despite complete surgical extirpation of tumor or institution of aggressive, multimodality treatment."( Jatoi, A, 2003)
"For oesophageal cancer there is no effective standard therapy."( Giaccone, G; Kroep, JR; Peters, GJ; Pinedo, HM; Van Bochove, A; Van Groeningen, CJ, 2004)
"A 70-year-old patient with advanced esophageal cancer with invasion to the aorta was treated by combined chemotherapy of TS-1 and CDDP with radiotherapy."( Doi, R; Indou, T; Iwase, H; Iyo, T; Kaida, S; Nakarai, K; Okeya, M; Shimada, M, 2004)
"PBIT reduced the incidence of esophageal cancer from 96% in NMBA-treated rats to 83% and 77% (P < 0."( Chen, T; Kresty, LA; Nines, RG; Peschke, SM; Stoner, GD, 2004)
"A 51-year-old male patient with esophageal cancer and cervical, thoracic and celiac artery lymph node metastases was treated by combination chemotherapy of TS-1 and cisplatin."( Doi, R; Iwase, H; Kaida, S; Nakarai, K; Okeya, M; Shimada, M; Tsuzuki, T, 2004)
"At initial diagnosis of esophageal cancer, positron emission tomography detects more distant lymph node and organ metastases compared with conventional diagnostics, allowing a more accurate selection of the most appropriate treatment."( Flamen, P, 2004)
"Treatment of oesophageal cancer depends on staging and the general health of the patient."( Brink, I; Hentschel, M; Hopt, UT; Imdahl, A; Kleimaier, M, 2004)
"Surgery, the mainstay of treatment of esophageal cancer, has been used with neoadjuvant chemoradiotherapy to improve prognosis in patients with localized disease."( Dehdashti, F; Siegel, BA, 2004)
"After radiotherapy for advanced esophageal cancer, the survival period of the cases ranged from 14 to 22 mo, with a mean survival of 17 mo."( Liu, Y; Shen, BZ; Yang, G; Yu, YT, 2004)
"Forty patients with esophageal cancer eligible for radical esophagectomy were randomly assigned to an experimental group ( n = 20), given perioperative PGE1, or to a control group ( n = 20), given standard postoperative treatment."( Akiyama, S; Fujiwara, M; Ito, K; Kasai, Y; Nakao, A; Oda, K; Sakamoto, J; Sekiguchi, H, 2004)
"Patients with previously untreated esophageal cancer were eligible if they had performance status 0-1, were 75 years or younger and had adequate organ function."( Fujitani, K; Hirao, M; Tsujinaka, T, 2004)
"This is a report of a case with esophageal cancer in which pathological CR was obtained by neoadjvant chemoradiotherapy using a low-dose of nedaplatin (CDGP)/5-FU."( Fujiwara, Y; Higashino, M; Iwasaki, H; Kaneko, M; Lee, S; Nishizawa, S; Osugi, H; Takemura, M; Tanaka, Y, 2004)
"A 66-year-old patient, who had advanced esophageal cancer with lymph node metastasis, was treated by neoadjuvant chemo-radiotherapy, followed by curative surgery."( Kabashima, A; Matsusaka, T; Nishizaki, T; Ojima, Y; Sakaguchi, Y; Shimabukuro, R; Tashiro, H; Yamamoto, H; Yamamura, S, 2004)
"Cultured lung and esophageal cancer cells were treated with calphostin C and trichostatin A."( Cole, GW; Maxhimer, JB; Nguyen, DM; Reddy, RM; Schrump, DS; Zuo, J, 2005)
"Treatment of non operable esophageal cancer still remains debatable."( François, E; Lagrange, JL; Magné, N; Marcy, PY; Touati, L; Van Houtte, P, 2005)
"Forty-three patients with a T4 esophageal cancer were enrolled in a prospective study in which each patient decided for themselves a treatment arm, CRT-followed-by-esophagectomy or esophagectomy-followed-by-CRT."( Fujita, H; Hayabuchi, N; Inutsuka, H; Sasahara, H; Shirouzu, K; Sueyoshi, S; Suzuki, G; Tanaka, T; Tanaka, Y, 2005)
"Recently in esophageal cancer, radiation therapy has been more frequently combined with other modalities including chemotherapy and surgery."( Badzio, A; Jassem, J; Serkies, K, 2005)
"Treatment of esophageal cancer cells with smoothened antagonist, KAAD-cyclopamine, or the neutralizing antibodies of Shh reduces cell growth and induces apoptosis."( Adegboyega, PA; Chen, K; He, J; Huang, S; Ma, X; Sheng, T; Sultz, J; Xie, J; Zhang, H; Zhang, X; Zhang, Y, 2006)
"Sixty-one patients operated for esophageal cancer from 1996 to 2000 were treated postoperatively with low dose dopamine (300 microg/kg/h), gabexate mesilate (80 mg/h), and ulinastatin (300 000 unit/day) as a study group."( Fujii, Y; Ishiguro, H; Kimura, M; Kuwabara, Y; Sato, A; Shinoda, N, 2005)
"Twenty-two patients with localized esophageal cancer suitable for curative chemoradiation therapy and 24 patients suitable for palliative therapy were enrolled."( Burmeister, BH; Burmeister, EA; Gotley, DC; Harvey, JA; Mark Smithers, B; Thomas, J; Thomson, DB; Walpole, ET, 2005)
"For locally advanced esophageal cancer, the combination of esophagectomy, post-operative CCRT with weekly cisplatin and systemic adjuvant chemotherapy is well tolerated and effective."( Chang, CC; Chen, CC; Chen, MJ; Chen, YJ; Huang, CJ; Hung, SK; Liu, HC; Lu, LH; Tai, CJ; Tzen, CY, 2005)
"Data from 110 esophageal cancer patients treated between January 1998 and December 2003 were analyzed retrospectively."( Ajani, JA; Cox, JD; Komaki, R; Liao, Z; Liu, H; Swisher, S; Tucker, SL; Vaporciyan, AA; Wang, SL; Wei, X, 2006)
"We have experienced four cases of esophageal cancer treated by weekly DOC in combination with concomitant radiotherapy."( Ami, K; Ando, M; Nagahama, T; Ohbu, M, 2005)
"Fifty-two patients with resectable esophageal cancers (cT2-4, Nx, and M0) received neoadjuvant radiochemotherapy (cisplatin, 5-5-fluorouracil, 36 Gy) followed by transthoracic en bloc esophagectomy."( Baldus, SE; Bollschweiler, E; Brabender, J; Dienes, HP; Hoelscher, AH; Ling, FC; Metzger, R; Moenig, S; Mueller, RP; Neiss, S; Schneider, PM; Warnecke-Eberz, U; Xi, H, 2005)
"Treatment of esophageal cancer cells with 5-Fu and cisplatin induced NF-kappaB and AP-1 activation."( Abdel-Latif, MM; Kelleher, D; Raouf, AA; Reynolds, JV; Sabra, K, 2005)
"This study is the first to evaluate esophageal cancer treatment with a pharmacogenetic paradigm and its application of pharmacogenetic analysis to multiple genes in each drug action pathway as a means of developing a more accurate and consistent risk prediction model."( Ajani, JA; Chiang, SS; Lu, C; Wu, X, 2005)
"Our data suggest that esophageal cancers with activated NF-kappaB have aggressive clinical biology and poor treatment outcome."( Aggarwal, BB; Ajani, JA; Chao, KS; Ensor, J; Hittelman, WN; Izzo, JG; Lee, JH; Liao, Z; Luthra, R; Malhotra, U; Swisher, SG; Wu, TT, 2006)
"Multimodality therapy for esophageal cancer holds promise for improving outcome in this lethal disease."( Beard, M; Cheng, JD; Freedman, G; Goldberg, M; Henry, LR; Konski, A; McLaughlin, S; Meropol, NJ; Scott, W; Watts, P; Weiner, LM, 2006)
"Human esophageal cancers have been shown to express high levels of epidermal growth factor receptor (EGFR) and a relationship between high EGFR expression and local advance, the number of lymph node metastases, life expectancy, and sensitivity to chemo-radiotherapy has been demonstrated."( Doihara, H; Hara, F; Ishibe, Y; Oota, T; Shien, T; Shimizu, N; Taira, N; Takahashi, H; Yoshitomi, S, 2006)
"Twenty-one patients operated on for oesophageal cancer in 2003-2004 were treated with perioperative steroid therapy (250 mg of methylprednisolone intravenously 1 h before the operation)."( Fukai, Y; Fukuchi, M; Katoh, H; Kimura, H; Kuwano, H; Manda, R; Masuda, N; Miyazaki, T; Nakajima, M; Sohda, M; Tsukada, K, 2006)
"Approximately 25% of esophageal cancer patients experience a pathologic complete response (pCR) to preoperative chemoradiation therapy."( Blackstock, AW; Clark, P; Farmer, MR; Geisinger, KR; Ho, C; Levine, EA; Lovato, J; Melin, SA; Mishra, G; Oaks, T, 2006)
"Patients with advanced esophageal cancer, who had failed one line of prior chemotherapy, were administered gefitinib 500 mg/d."( Gallegos-Ruiz, MI; Giaccone, G; Janmaat, ML; Meijer, GA; Richel, DJ; Rodriguez, JA; Van Groeningen, C; Vervenne, WL, 2006)
"We report a patient with advanced esophageal cancer who achieved a complete response to combination chemotherapy of TS-1, docetaxel and CDDP."( Kitakata, H; Omote, K; Takahashi, Y; Yamashita, K; Yasumoto, K, 2006)
"Early identification of esophageal cancer patients who are responding or resistant to combined chemoradiotherapy may lead to individualized therapeutic approaches and improved clinical outcomes."( Ajani, JA; Alauddin, MM; Apisarnthanarax, S; Ariga, H; Bornmann, WG; Chao, KS; Gelovani, JG; Han, D; Mawlawi, O; Milas, L; Mourtada, F; Raju, U, 2006)
"Patients with no prior treatment and oesophageal cancer stage I to III, performance status <3, caloric intake >1,500 kcal day(-1) were included."( Adenis, A; Boucher, E; Dahan, L; Di Fiore, F; Galais, MP; Hamidou, H; Hellot, MF; Jacob, JH; Michel, P; Mirabel, X; Paillot, B; Prod'homme, S; Raoul, JL, 2006)
"Thirty-two patients with localised oesophageal cancer had a pretreatment PET scan and a repeat after the first week of chemoradiation."( Duffy, GJ; Gillham, CM; Hollywood, D; Keogan, M; Lucey, JA; Malik, V; Muldoon, C; O'byrne, K; Raouf, AA; Reynolds, JV, 2006)
"The major aims of imaging in esophageal cancer are to distinguish between locoregional and systemic disease (M-stage), to determine local tumor extension (T- and N-stage), to assess response to chemo- or chemoradiotherapy and to identify recurrence of cancer."( Ott, K; Siewert, JR; Weber, W, 2006)
"In total, 28 patients with recurrent esophageal cancer after the initial treatment (esophagectomy, chemotherapy and/or chemoradiotherapy) were enrolled."( Aoki, T; Hoshino, S; Osaka, Y; Tachibana, S; Takagi, Y; Tsuchida, A, 2006)
"Neoadjuvant treatment modalities for esophageal cancer were developed to improve local tumor control as well as to reduce lymph node metastases and distant metastases in patients with locally advanced esophageal cancer."( Baldus, SE; Bollschweiler, E; Dienes, HP; Hölscher, AH; Izbicki, JR; König, A; Mueller, RP; Prenzel, KL; Schneider, PM; Schnickmann, C; Schröder, W, 2007)
"The major aims of imaging in esophageal cancer are to determine local tumor extension (T and N staging), to rule out systemic disease (M staging), and to assess response to neoadjuvant therapy (response evaluation)."( Beer, AJ; Hannig, C; Holzapfel, K; Rummeny, EJ, 2007)
"He was diagnosed as having esophageal cancer of stage IVa (T2N4M0) in October, 2002, and he received chemoradiotherapy (nedaplatin (CDGP)/5-fluorouracil (5-FU) total 6 course+60 Gy)."( Chinen, T; Fujita, J; Hirata, T; Hokama, A; Kinjo, F; Kinjo, N; Nakachi, N; Nakamoto, M; Uchima, N; Watanabe, T, 2007)
"The data from 36 patients treated for esophageal cancer with thoracic radiotherapy who underwent restaging PET/CT imaging between 4 and 12 weeks after radiotherapy completion were evaluated."( Ajani, J; Guerrero, T; Hart, J; Johnson, V; Khan, M; Komaki, R; Liao, Z; Luo, D; Pan, T; Stevens, C, 2007)
"Thirty-four oesophageal cancer patients with co-morbid medical conditions, locally advanced tumours (T4) or advanced age (older than 75 years) received docetaxel (20 mg/m2 weekly) plus concurrent radiotherapy (2 Gy daily, to a total dose of 66 Gy)."( Abad, A; Arellano, A; Boix, J; Cardenal, J; Casas, D; Fernández-Llamazares, J; Font, A; Manzano, JL; Margelí, M; Rosell, R, 2007)
"Since esophageal cancer has often metastasized at the time of diagnosis, current treatment modalities offer poor survival and cure rates."( Chen, T; Stoner, GD; Wang, LS, 2007)
"Patients with local/regional oesophageal cancer with adequate functional status should not be excluded from potentially curative treatment based on age alone."( Anderson, SE; Bains, M; Hummer, A; Ilson, DH; Kelsen, D; Minsky, BD, 2007)
"For patients with localized esophageal cancer, whether or not preoperative chemotherapy is administered, only an R0 resection results in substantial long-term survival."( Ajani, JA; Estes, NC; Gunderson, LL; Haller, DG; Kelsen, DP; Kocha, W; Minsky, BD; Mortimer, J; Roth, JA; Willett, CG; Winter, KA, 2007)
"The incidence of oesophageal cancer (OC) has risen in recent decades, with survival rates remaining poor despite surgical treatment and adjuvant chemotherapy."( Deasy, BM; McKenna, SL; O'Donovan, TR; O'Sullivan, GC; O'Sullivan-Coyne, G, 2007)
"Locally advanced esophageal cancer is challenging to treat."( Alberts, SR; Fitch, TR; Foster, NR; Jatoi, A; Lair, BS; Martenson, JA; McLeod, HL; Moore, DF; Nichols, F; Tschetter, LK, 2007)
"Patients with esophageal cancer often develop metastatic disease after esophageal resection and generally receive cisplatin-based chemotherapy or chemoradiotherapy."( Fujita, H; Mori, N; Nagano, T; Sasahara, H; Shirouzu, K; Sueyoshi, S; Tanaka, T; Tanaka, Y; Yamana, H, 2007)
"Twenty patients with metastatic esophageal cancer after esophagectomy refractory to cisplatin-based therapy were included in this study."( Fujita, H; Mori, N; Nagano, T; Sasahara, H; Shirouzu, K; Sueyoshi, S; Tanaka, T; Tanaka, Y; Yamana, H, 2007)
"Six patients with recurrent esophageal cancer after external radiotherapy were treated with HDR brachytherapy (Ir-192 source) from January 2003 to February 2004."( Hirata, H; Honda, H; Nakamura, K; Nonoshita, T; Sasaki, T; Shioyama, Y; Toh, Y, 2007)
"Patients with stage I or II esophageal cancer received preoperative radiation therapy (28-30 daily 1."( Adenis, A; Lartigau, E; Mariette, C; Mirabel, X; Sarrazin, T; Triboulet, JP, 2008)
"Twenty-six patients with distal esophageal cancer who received chemoradiotherapy before esophagectomy were included."( Balachandran, A; Bruzzi, JF; Iyer, RB; Johnson, V; Macapinlac, HA; Munden, RF, 2007)
"All cervical esophageal cancer patients treated between 1997 and 2005 were restaged (1983 American Joint Committee on Cancer criteria)."( Bayley, A; Brierley, J; Cummings, B; Huang, SH; Kim, J; Lockwood, G; Ringash, J; Wong, R, 2008)
"In locally advanced esophageal cancer it has been proved that the definitive radiochemotherapy is an alternative at radiochemotherapy plus surgery."( Di Fiore, F; Michel, P, 2008)
"In patients with advanced esophageal cancer, treatment with an esophageal stent loaded with (125)I seeds, compared with that with a conventional covered stent, has potential benefit in that it allows a slightly longer relief of dysphagia and extended survival."( Deng, G; Fang, W; Guo, JH; He, SC; Li, GZ; Teng, GJ; Zhu, GY, 2008)
"A 64-year-old woman with advanced esophageal cancer underwent chemotherapy with docetaxel/5-FU/CDDP (DFP)."( Honda, J; Matsuoka, H; Miyoshi, T; Seike, J; Tangoku, A; Yamai, H; Yoshida, T; Yuasa, Y, 2008)
"Between 1998 and 2004, 66 esophageal cancer patients with adjuvant chemotherapy and 160 well-matched patients without chemotherapy were included in this study."( Chen, ZW; Hu, H; Lu, S; Luo, QQ; Ma, LF; Miao, LS; Xiang, JQ; Zhang, J; Zhang, YW; Zhou, XY, 2008)
"In 71 patients with esophageal cancer who underwent neoadjuvant chemotherapy (cisplatin, adriamycin and 5-fluorouracil) followed by surgery, plasma d-dimer levels were measured before chemotherapy and the clinical and pathological responses to chemotherapy were assessed at 4 weeks after therapy (after surgery)."( Imaoka, S; Ishikawa, O; Kishi, K; Miyashiro, I; Ohigashi, H; Ohue, M; Sasaki, Y; Takachi, K; Tomimaru, Y; Yano, M, 2008)
"The treatment of choice for esophageal cancer is considered surgical resection, but a median survival of around 20 months after treatment is still discouraging."( Bulut, D; Chromik, AM; Daigeler, A; Geisler, A; Hilgert, C; Klein-Hitpass, L; Krieg, A; Lehnhardt, M; Mittelkötter, U; Uhl, W, 2008)
"DCE-MRI is feasible in patients with esophageal cancer, reveals therapeutic effects, and may thus be useful in therapy management and monitoring."( Düber, C; Junginger, T; Kunz, P; Mildenberger, P; Oberholzer, K; Pohlmann, A; Schmidberger, H; Schreiber, W, 2008)
"Fifty-two esophageal cancer patients undergoing FDG-PET as part of initial routine staging procedure before treatment were included."( Cheze-Le Rest, C; Jestin-Le Tallec, V; Lozac'h, P; Metges, JP; Teyton, P; Visvikis, D; Volant, A, 2008)
"Patients with localized esophageal cancer (LEC) have diverse outcomes (post-therapy pathologic response, disease-free survival [DFS], and overall survival [OS]) after preoperative chemoradiation (P-CTRT), dictated also by inherent molecular heterogeneity."( Ajani, JA; Arora, R; Bhutani, MS; Correa, AM; Hofstetter, WL; Izzo, JG; Javeri, H; Lee, JH; Liao, Z; Maru, D; McAleer, MF; Swisher, SG, 2008)
"Treatment of oesophageal cancer cell lines with 5-aza-2'-deoxycytidine and trichostatin-A led to reversal of the methylation pattern and re-expression of these genes at the mRNA and protein levels."( Chen, H; El-Rifai, W; Peng, DF; Razvi, M; Roessner, A; Schneider-Stock, R; Washington, K, 2009)
"We present a case of esophageal cancer with multiple lymph node metastases successfully performed early response evaluation for preoperative chemotherapy by FDG-PET."( Arakaki, K; Isa, T; Kaneshiro, T; Nakachi, A; Nishimaki, T; Shiroma, H; Teruya, T; Yamamoto, H, 2008)
"Ten patients with gastro-oesophageal cancer referred for radiation therapy underwent both (18F)fluoro-2-deoxy-d-glucose-PET (FDG-PET) and computed tomography in the treatment position."( Breen, S; Brock, K; Cheung, F; Darling, G; Dinniwell, R; Grabarz, D; Haider, M; Kamra, J; Knox, J; Mah, K; Mansouri, A; Pond, G; Ung, Y; Vesprini, D; Wong, RK, 2008)
"Fourteen patients with localised oesophageal cancer suitable for curative chemoradiation therapy registered on the study."( Burmeister, BH; Burmeister, EA; Cox, S; D'Arcy, N; Harvey, JA; Smithers, BM; Thomson, DB; Walpole, ET, 2009)
"Early detection of esophageal cancer in patients with head and neck cancers may alter treatment planning and improve survival."( Chen, CC; Chiu, HM; Hsiu-Hsi Chen, T; Huang, HY; Ko, JY; Lee, YC; Lin, JT; Lou, PJ; Wang, CP; Wang, HP; Wu, MS; Yang, TL, 2009)
"We report here a case of esophageal cancer patient who developed tumor lysis syndrome after chemotherapy."( Nishimura, T; Oka, M; Takeda, S; Tokunou, K; Yoshino, S, 2008)
"In patients with esophageal cancer who receive chemoradiation, tools to predict/prognosticate outcome before administering therapy are lacking."( Ajani, JA; Bhutani, MS; Hofstetter, W; Javeri, H; Komaki, R; Lee, JH; Maru, D; Rohren, E; Swisher, SG; Wang, X; Xiao, L, 2009)
"Among the 65 patients with advanced esophageal cancer, 27 had no history of prior chemotherapy and the other 38 had ever received postoperative adjuvant chemotherapy before."( Chen, XB; Fan, QX; Geng, L; Han, JW; Jiao, ZM; Lu, P; Lu, SP; Lu, TY; Luo, SX; Ma, ZY; Song, M; Wang, GJ; Wang, JS; Wang, R; Wang, RL; Wu, XA; Zhang, MZ; Zhao, YF, 2008)
"In patients with locally advanced esophageal cancer, preoperative chemotherapy or chemoradiotherapy has been shown to improve outcome with respect to survival."( Herrmann, K; Krause, BJ; Wieder, H; zum Büschenfelde, CM, 2009)
"A xenograft model using SCID mice with esophageal cancer cells would monitor gene changes during treatment and regrowth."( Miyoshi, T; Seike, J; Takechi, H; Tangoku, A; Yamai, H; Yoshida, T; Yuasa, Y, 2009)
"Anderson Cancer Center for esophageal cancer and who had undergone [(18)F]-fluorodeoxyglucose positron emission tomography/computed tomography between November 1, 2003 and December 15, 2007 for disease restaging after chemoradiotherapy."( Ajani, J; Baker, J; Ezhil, M; Guerrero, T; Johnson, V; Khan, M; Luo, D; McAleer, MF; McCurdy, M; Wei, W, 2010)
"One patient with esophageal cancer and one with gastric cancer treated with RAD001 at 10 mg/day showed marked tumor responses."( Doi, T; Kobayashi, K; Kurei, K; Miyazaki, M; Nakagawa, K; Ohtsu, A; Okamoto, I; Tsuya, A, 2010)
"Sixty inpatients with advanced esophageal cancer from Henan Tumor Hospital, and the Fist Affiliated Hospital of Zhengzhou University were included and randomly divided into treatment group and control group."( Fan, QX; Huang, JY; Sun, Y; Zhang, YQ, 2009)
"The standard chemotherapy regimen for esophageal cancer is cisplatin and 5-fluorouracil (5-FU)."( Oka, M; Takeda, S; Tsutsui, M; Watanabe, Y; Yoshino, S, 2009)
"We have experienced a case of advanced esophageal cancer that has come back eight years after combined modality therapy, and after that, the patient could obtain a long-term survival with a marked effect of chemotherapy."( Aoyama, N; Minamide, J; Ota, Y; Takata, K, 2009)
"In patients with advanced gastric and esophageal cancer who were not candidates for every-3-week DCF, a weekly formulation of DCF demonstrated modest activity with minimal hematologic toxicity, suggesting that weekly DCF is a reasonable treatment option for such patients."( Abbruzzese, JL; Ajani, J; Ho, L; Jhamb, J; Kazmi, SM; Lin, E; Overman, MJ; Phan, A; Yao, JC, 2010)
"Patients with deeply invading (T3-T4) oesophageal cancers usually receive chemoradiotherapy with or without surgery."( Doki, Y; Fujiwara, Y; Miyata, H; Mori, M; Nakajima, K; Takiguchi, S; Yamasaki, M, 2010)
"In this patient, esophageal cancer associated with Fanconi anemia responded well to multidisciplinary therapy."( Hirashima, Y; Hosoya, Y; Jinbu, Y; Lefor, A; Muroi, K; Nakazawa, M; Nokubi, M; Yamaguti, T; Yasuda, Y, 2010)
"We treated esophageal cancer cells with BPDE before performing methylation-specific polymerase chain reaction (MSP) to find that BPDE induced methylation of the RAR-beta2 gene promoter."( Xu, XC; Ye, F, 2010)
"In our hospital, 348 patients with esophageal cancer received chemotherapy consisting of nedaplatin and 5-fluorouracil and concurrent irradiation."( Ise, M; Kumagai, K; Mimura, N; Nagata, M; Sakai, C; Takagi, T; Tsujimura, H, 2010)
"Five paired samples from oesophageal cancer patients before and after chemotherapy were analysed using the same methodology."( Appleyard, V; Baker, L; Exon, D; Kelly, P; Lamont, D; Murray, K; Paulin, F; Suttie, S; Thompson, A, 2010)
"Between 1997 and 2007, 94 patients with esophageal cancer were treated with chemoradiation in our institute."( Aleman, BM; Boot, H; Cats, A; Courrech Staal, EF; Jansen, EP; van Coevorden, F; van Sandick, JW; van Velthuysen, ML, 2011)
"For most patients with esophageal cancer, esophagectomy is an effective therapy."( Hu, Y; Xie, T; Yuan, Y; Zhao, Y, 2010)
"Untreated stage II-IVa esophageal cancer patients with performance status 0-2 were included."( Ansari, RH; Choong, NW; Ferguson, MK; Fishkin, PA; Haraf, DC; Hoffman, PC; Kesler, KA; Kocherginsky, M; Krauss, SA; Mauer, AM; Posner, MC; Sandler, AB; Sciortino, DF; Szeto, L; Vokes, EE; Wade, J, 2011)
"Curative treatment of esophageal cancer with definitive or preoperative high-dose chemoradiotherapy inflicts a major strain on the patients with potentially severe physical, emotional, and social consequences."( Aarstad, AK; Aarstad, HJ; Hjermstad, MJ; Hurmuzlu, M; Viste, A, 2011)
"A 77-year-old male with thoracic esophageal cancer (cT3N3M0, Stage III) received nedaplatin at 80mg/m2 for 1 day and 5-fluorouracil at 800mg/m2 for 5 days as neoadjuvant treatment."( Gyobu, K; Hashiba, R; Isohata, N; Iwasaki, H; Kishida, S; Lee, S; Matsuda, Y; Mori, K; Osugi, H, 2010)
"A 72-year-old man with esophageal cancer who could not sit down or stand up was administered 5 mg/day haloperidol to relieve agitation as a symptom of major depressive disorder."( Ishida, M; Ito, H; Kawanishi, C; Mizuno, K; Narabayashi, M; Onishi, H; Sasaki, Y; Wada, M; Wada, T, 2010)
"To improve the prognosis of advanced esophageal cancer, neoadjuvant chemotherapy (NACT) followed by surgery is a promising treatment strategy."( Doki, Y; Fujiwara, Y; Komori, T; Matsubara, K; Matsuura, N; Miyata, H; Monden, M; Mori, M; Motoori, M; Takemasa, I; Takeno, A; Takiguchi, S; Yamasaki, M; Yano, M; Yasuda, T, 2010)
"Treatment options for localized gastroesophageal cancers reach from limited resection to multimodality treatment."( Krause, BJ; Lordick, F; Ott, K, 2010)
"Chemoradiotherapy (CRT) for esophageal cancer is disadvantageous because of a high locoregional failure rate."( Horimatsu, T; Ishikura, S; Minashi, K; Muto, M; Nihei, K; Ohtsu, A; Onozawa, M; Taku, K; Tu, CH; Yano, T; Yoshida, S, 2011)
"Locally advanced oesophageal cancer (LAEC) is associated with poor survival and more effective treatments are needed."( Day, FL; Di Iulio, J; Jefford, M; Leong, T; Matera, A; McKendick, J; Michael, M; Milner, AD; Ngan, S; Rischin, D; Thomas, R; Zalcberg, JR, 2011)
"A total of 8 esophageal cancer patients with relapsed mediastinal lymph nodes (6 patients), psychological disease (1 patient) and local advanced tumor (cT4) after initial 5-FU/CDDP therapy (1 patients) received docetaxel (10 mg/m2 weekly) plus concurrent radiotherapy (2 Gy daily, a total dose of 60 Gy)."( Amano, R; Hirakawa, K; Ishikawa, T; Kubo, N; Maeda, K; Morimoto, J; Muguruma, K; Nagahara, H; Nakata, B; Noda, E; Ohira, M; Onoda, N; Sakurai, K; Sawada, T; Takashima, T; Tanaka, H; Yamada, N; Yashiro, M, 2010)
"We present a case of advanced esophageal cancer with multiple lymph node metastases successfully treated by combination therapy of docetaxel, cisplatin and 5-FU (DCF) followed by salvage lymphadenectomy."( Kanemura, T; Kobayashi, M; Miki, H; Nakahira, S; Nakata, K; Okamura, S; Ono, H; Suzuki, R; Takeda, Y; Takeno, A; Tamura, S; Uchiyama, C; Yanai, A; Yoshioka, Y, 2010)
"We report here a case of recurrent esophageal cancer successfully treated by cervical lymph node dissection and chemo-radiation therapy."( Andoh, S; Kitamura, Y; Tokunou, K; Toshimitsu, H; Tsushimi, K; Yamamoto, T, 2010)
"This chemotherapy reduced the esophageal cancer mass significantly, and subtotal esophagectomy was performed."( Hamatsu, T; Hasegawa, H; Honboh, T; Kabashima, A; Kitamura, M; Kudo, K; Ninomiya, M; Ushijima, C, 2010)
"Forty-one patients with newly diagnosed esophageal cancer treated with combined radiochemotherapy were included in this study."( Albarghach, N; Corcos, L; Hatt, M; Le Rest, CC; Metges, JP; Pradier, O; Tixier, F; Visvikis, D, 2011)
"A total of 43 patients with esophageal cancer, who were candidates for esophagectomy (without neo-adjuvant chemotherapy), were enrolled in this study from 2007 to 2009."( Bagheri, R; Maddah, G; Roodbari, S; Sadeghian, MH; Saedi, HS, 2011)
"Advanced esophageal cancer with widespread metastasis to lymph nodes or other organs is difficult to treat and has an extremely poor prognosis."( Aoki, T; Hoshino, S; Ogata, T; Osaka, Y; Shinohara, M; Takagi, Y; Tsuchida, A, 2011)
"Fifty patients with oesophageal cancer treated with concomitant radiochemotherapy between 2004 and 2008 were retrospectively considered and classified as complete, partial or non-responders (including stable and progressive disease) according to Response Evaluation Criteria in Solid Tumors (RECIST)."( Cheze-le Rest, C; Hatt, M; Pradier, O; Visvikis, D, 2011)
"Recent data in esophageal cancer suggests the variant allele of a single-nucleotide polymorphism (SNP) in XRCC1 may be associated with resistance to radiochemotherapy."( Benson, AB; Catalano, PJ; Forastiere, AA; Gibson, MK; Hafez, MJ; Kleinberg, LR; Liu, G; Meltzer, SJ; Montgomery, EA; Murphy, KM; Offer, SM; Philips, S; Powell, M; Skaar, TC; Wu, X; Yoon, HH, 2011)
"Treatment of esophageal cancer cell lines with the phorbol ester phorbol 12,13 dibutyrate led to a rapid and dramatic increase in the activation of protein kinase D."( Carballo, M; Maish, MS; Yetasook, A, 2011)
"A total of 139 esophageal cancer patients treated with CCRT (cisplatin-based chemotherapy combined with 40 Gy of irradiation) and subsequent esophagectomy were recruited at the National Taiwan University Hospital between 1997 and 2008."( Chen, PC; Chen, SK; Chen, YC; Chuang, EY; Hsiao, CK; Lai, LC; Lee, JM; Lee, YC; Tsai, MH; Yang, PW, 2012)
"Because most esophageal cancers are diagnosed at an advanced stage, a majority of patients require palliative dysphagia treatment."( Butruk, E; Fijuth, J; Kraszewska, E; Polkowski, M; Regula, J; Rupinski, M; Wronska, E; Zagorowicz, E, 2011)
"In patients with inoperable esophageal cancer, palliative combination treatment of dysphagia with APC and HDR or PDT was significantly more efficient than APC alone, and was safe and well tolerated."( Butruk, E; Fijuth, J; Kraszewska, E; Polkowski, M; Regula, J; Rupinski, M; Wronska, E; Zagorowicz, E, 2011)
"CR to CRT for the esophageal cancer and CR to chemotherapy for the gastric cancer were achieved."( Fujii, M; Funada, T; Kaiga, T; Kanamori, N; Kochi, M; Mihara, Y; Takayama, T; Tamegai, H; Watanabe, M; Yoshida, N, 2011)
"Twenty patients with advanced esophageal cancer who underwent cisplatin-based neoadjuvant chemotherapy were enrolled in a prospective observational study."( Doki, Y; Fujiwara, Y; Hiura, Y; Kurokawa, Y; Miyata, H; Mori, M; Nakajima, K; Takiguchi, S; Yamamoto, K; Yamasaki, M, 2012)
"A total of 104 patients with advanced esophageal cancer received 2 courses of NAF-chemotherapy between February 2003 and March 2010."( Fujitani, K; Hasegawa, H; Hirao, M; Mita, E; Nakazuru, S; Tsujinaka, T, 2011)
"Fifteen patients with esophageal cancer received chemotherapy, six of whom had grade one oral mucositis."( Fukui, T; Itoh, Y; Kawada, S; Orihara, M; Takeda, H; Yoshioka, T; Yoshizawa, K, 2011)
"A positive effect of MSH on esophageal cancer has been demonstrated, however, there is no study on the in vitro effects of heating treatment or of the effects of AMF exposure on human esophageal cancer cells."( Li, DY; Li, LY; Liu, JY; Tang, JT; Tao, D; Wang, YY; Zhao, LY, 2012)
"We report a rare case of esophageal cancer resection in which lung metastases was resected after chemotherapy with paclitaxel."( Inoue, S; Miyata, M; Ohashi, I; Takami, K; Tamura, C; Wakasa, T, 2011)
"Fifty patients with esophageal cancer treated with concomitant radiochemotherapy between 2004 and 2008 were retrospectively considered."( Cheze Le Rest, C; Hatt, M; Le Pogam, A; Pradier, O; Visvikis, D, 2012)
"The prevalence of esophageal cancer during the pretreatment of HPC patients was 51."( Kawano, T; Kishimoto, S; Makino, T; Nakaminato, S; Shibuya, H; Toriihara, A, 2012)
"For cT2 N0 esophageal cancer patients, the benefit of neoadjuvant therapy is still unclear."( Brock, MV; Franco, N; Hooker, CM; How, R; Hulbert, A; Lee, S; Prevas, H; Shin, J; Yang, SC; Zhang, JQ, 2012)
"Forty-two patients with esophageal cancer who were receiving cisplatin-based neoadjuvant chemotherapy were assigned to either a ghrelin group (n = 21) or a placebo group (n = 21)."( Doki, Y; Fujiwara, Y; Hiura, Y; Kangawa, K; Kurokawa, Y; Miyata, H; Mori, M; Nakajima, K; Takahashi, T; Takiguchi, S; Yamamoto, K; Yamasaki, M, 2012)
"Current chemotherapy for esophageal cancer is conducted on the basis of empirical information from clinical trials, which fails to take into account the known heterogeneity of chemosensitivity between patients."( Fang, XH; Gu, LH; Ling, ZQ; Lu, XX; Mao, WM; Qi, CJ; Qian, LJ; Wang, S; Yang, ZX; Yin, J; Zhao, Q; Zheng, ZG, 2012)
"One hundred and sixty eight patients of esophageal cancer were randomly divided into 3 groups, including the radiotherapy alone group (CF) which received conventional conformal radiotherapy to a total of 60 - 66 Gy, LCAF group which received conventional fractionated conformal radiotherapy during the first two-thirds of the treatment to a dose about 40 Gy/20F/4W, then followed by late accelerated hyperfractionated conformal radiotherapy, twice daily radiotherapy at 1."( Feng, XZ; Han, JQ; Sheng, W, 2011)
"Concurrent chemoradiotherapy for esophageal cancer impairs LVF from an early treatment stage."( Hatakenaka, M; Higo, T; Honda, H; Kamitani, T; Matsuo, Y; Nagao, M; Nakamura, K; Nishikawa, K; Nonoshita, T; Setoguchi, T; Shioyama, Y; Yabuuchi, H; Yonezawa, M, 2012)
"In this study, patients with oesophageal cancer were divided into two group: one with neoadjuvant therapy and the other without neoadjuvant therapy."( Asnaashari, A; Bagheri, R; Ghazvini, K; RajabiMashhadi, MT; Sahebi, MA; Zahediyan, A, 2012)
"Treatment options for oesophageal cancer have changed considerably over the last decades with the introduction of multimodal treatment concepts dominating the progress in the field."( Belka, C; Hölzel, D; Schmidt, M; Wolf, MC; Zehentmayr, F, 2012)
"By this stage of esophageal cancer, surgery, although very invasive, is the standard radical therapy for the patients."( Kameda, Y; Ohkawa, S; Tamai, S; Yoshii, T, 2013)
"The treatment results for cT4 esophageal cancer were examined in 81 patients who received definitive CRT [radiation 50-70 Gy, cisplatin and 5-fluorouracil; group I] and 19 patients who underwent esophagectomy after preoperative CRT [40Gy, Group II]."( Ikeda, Y; Maehara, S; Maehara, Y; Minami, K; Morita, M; Ohgaki, K; Okamura, T; Saeki, H; Sakaguchi, Y; Sugiyama, M; Toh, Y; Uehara, S, 2012)
"In patients treated for an esophageal cancer, the present study suggested that 18F-fluorodeoxyglucose-positron emission tomography after chemoradiotherapy completion was an independent prognostic factor of overall survival without significant impact on local recurrence prediction."( Benyoucef, A; Blondin, V; Di Fiore, F; Edet-Sanson, A; Hitzel, A; Huet, E; Michel, P; Vera, P, 2012)
"Eighty patients with esophageal cancer were enrolled in the study between January, 2004 and December, 2007, who were randomly divided into two groups of 40, one of which was treated with hand-video-assisted thoracoscopy surgery (HVATS) esophagectomy and one of which was treated with conventional surgery."( Dong, W; Du, J; Li, X; Meng, L; Ni, Y; Shen, H; Wang, G, 2012)
"HAI can be a treatment of choice for esophageal cancer when metastasis is limited to the liver."( Hasegawa, H; Ikebe, M; Kitamura, M; Saitoh, G, 2012)
"We retrospectively studied 100 esophagus cancer patients treated with proton therapy."( Bernard, V; Buckley, W; Castillo, E; Castillo, R; Echeverria, AE; Guerrero, T; Liu, P; Martinez, J; McCurdy, M; Ramos, NV, 2013)
"Twenty patients with esophageal cancer were treated with trimodal therapy (CRT plus surgery) and underwent [(18)F]FDG-PET/CT scans both before (pre-CRT) and after (post-CRT) CRT."( Chen, W; D'Souza, WD; Feigenberg, S; Kim, G; Kligerman, S; Lu, M; Lu, W; Suntharalingam, M; Tan, S, 2013)
"One-hundred and twenty patients with esophageal cancer treated by an association of radiotherapy and chemotherapy and possibly surgery, between 2004 and 2010, were retrospectively studied."( Capitain, O; Cellier, P; Denis, F; Girault, S; Hamy, A; Mahé, MA; Mesgouez-Nebout, N; Paumier, A; Poirier, AL; Rousseau, D, 2013)
"Fourteen patients with esophageal cancer were enrolled and received DNF combination therapy at different dose levels according to the treatment and examination plan."( Fukuchi, M; Ieta, K; Inose, T; Kato, H; Kuwano, H; Miyazaki, T; Nakajima, M; Ojima, H; Sakai, M; Sano, A; Sohda, M; Suzuki, S; Tanaka, N; Yokobori, T, 2013)
"Patients with stage IVA esophageal cancer treated with chemoradiotherapy between April 2003 and March 2009 were evaluated."( Anbai, A; Hashimoto, M; Jin, M; Koga, M; Motoyama, S; Shibata, H, 2013)
"We enrolled 56 patients with esophageal cancer treated with definitive CRT and examined by FDG-PET before treatment."( Abe, K; Asai, K; Atsumi, K; Baba, S; Hirakawa, M; Honda, H; Isoda, T; Nakamura, K; Ohga, S; Sasaki, T; Shinoto, M; Shioyama, Y; Yoshitake, T, 2013)
"The survival rates of esophageal cancer treated with DCRT in North West of Iran is poor; therefore, early detection and improved treatment methods, with clinical trials are a high priority."( Ghojazadeh, M; Jangjoo, AG; Mirinezhad, SK; Mohammadzadeh, M; Naseri, AR; Nasiri, B; Seyednezhad, F; Somi, MH, 2013)
"Elderly patients with esophageal cancer who are not candidates for chemoradiation may benefit from targeted agents; hence erlotinib combined with radiotherapy was evaluated in this trial."( Chhatrala, R; Iyer, R; Khushalani, N; Levea, C; Malhotra, U; Robins, M; Shefter, T; Tan, W; Yang, G, 2013)
"We retrospectively studied 276 esophageal cancer patients treated with nCRT and surgery between 2002 and 2008."( Chan, SC; Chang, HK; Chao, YK; Chen, WH; Chiu, CH; Liu, YH; Tseng, CK, 2013)
"DNA from 143 esophageal cancer patients, 63 receiving neoadjuvant therapy and 80 receiving primary surgery, was analyzed for the following polymorphisms: the GSTM1 null, GSTT1 null, and GSTP1 Ile105Val (rs16953) in glutathione S-transferase (GST) family, 2 in thymidylate synthase (TS) gene, and the ERCC1 Asn118Asn (rs11615), ERCC1 C8092A (rs3212986), XPD/ERCC2 Asp312Asn (rs1799793), and XPD/ERCC2 Lys751Gln (rs13181) of the nucleotide excision repair pathway."( Alfieri, R; Amadori, A; Ancona, E; Basso, D; Boldrin, E; Cagol, M; Castoro, C; Cavallin, F; Rumiato, E; Ruol, A; Saggioro, D, 2013)
"Consecutive patients with oesophageal cancer who underwent neoadjuvant chemotherapy followed by surgery were studied."( Doki, Y; Kurokawa, Y; Miyata, H; Mori, M; Murakami, K; Nakajima, K; Takahashi, T; Takiguchi, S; Yamasaki, M, 2013)
"Twenty patients with esophageal cancer treated with CRT plus surgery were included in this study."( Chen, W; D'Souza, WD; Lu, W; Tan, S; Zhang, H; Zhang, Y, 2013)
"Between 2006 and 2012, a total of 96 esophageal cancer patients (staged cT1N+/T2-4a/N0-3 and M0) were treated according to the above neoadjuvant scheme."( Beukema, JC; Bosch, DJ; Burgerhof, JG; Hospers, GA; Muijs, CT; Mul, VE; Plukker, JT, 2014)
"In FP chemotherapy for oesophageal cancers, cisplatin-induced nephrotoxicity seems to be unaffected by the SLC22A2 808G>T polymorphism."( Hinai, Y; Miura, M; Motoyama, S; Niioka, T, 2013)
"A panel of gastric and esophageal cancer cell lines was treated with wortmannin as an Akt-signal inhibitor; the MAPK signal inhibitor PD98059; lapatinib, which inhibits both the epidermal growth factor receptor and HER2 tyrosine kinase; or siRNA for MAPK."( Fujii, H; Izawa, S; Kiessling, R; Kono, K; Kua, LF; Mimura, K; Mueller, A; Seliger, B; Shiraishi, K; So, J; Yong, WP, 2013)
"We treated 53 thoracic esophageal cancer patients who underwent surgery following neoadjuvant chemotherapy between January 2010 and December 2012."( Fujiwara, T; Katsube, R; Maeda, N; Noma, K; Ohara, T; Sakurama, K; Shirakawa, Y; Tanabe, S, 2013)
"The study population consisted of 63 esophageal cancer patients treated with neo-CRT."( Beukema, J; Hospers, G; Karrenbeld, A; Kluin, P; Langendijk, J; Muijs, C; Mul, V; Plukker, J; Smit, J; van Dam, G, 2014)
"However, the number of long-term esophageal cancer survivors has been increasing due to advances in early detection and therapy."( Dasanu, CA; Nandy, N, 2014)
"We discuss the association between esophageal cancer and subsequent second malignancies, along with implications for surveillance and therapy."( Dasanu, CA; Nandy, N, 2014)
"Neoadjuvant chemoradiotherapy (CRT) in esophageal cancer (EC) patients may increase the formation of thromboembolic events (TEEs)."( Bosch, DJ; Hospers, GA; Mul, VE; Plukker, JT; Van Dalfsen, QA, 2014)
"DCF has strong antitumor activity for esophageal cancer and may confer survival benefits when used as preoperative chemotherapy."( Baba, H; Baba, Y; Ishimoto, T; Iwagami, S; Iwatsuki, M; Nagai, Y; Watanabe, M; Yoshida, N, 2014)
"In 67 patients with advanced esophageal cancer, TF expression in pretreatment biopsy samples was evaluated immunohistochemically and correlated with clinicopathologic factors and response to chemotherapy."( Akita, H; Fujiwara, Y; Goto, K; Ishikawa, O; Kishi, K; Marubashi, S; Miyoshi, N; Motoori, M; Noura, S; Ohue, M; Sakon, M; Sugimura, K; Takahashi, H; Tanaka, K; Tomita, Y; Yano, M, 2014)
"A database of esophageal cancer was queried for nonmetastatic patients with adenocarcinoma treated between 2000 and 2011 with CRT."( Almhanna, K; Freilich, J; Fulp, WJ; Hoffe, SE; Karl, RC; Meredith, K; Shridhar, R; Yue, B, 2014)
"In the UK, the standard of care for esophageal cancer has generally combined surgery with neoadjuvant chemotherapy, with definitive chemoradiotherapy (dCRT) being reserved for certain subgroups."( Cook, N; Gilligan, D; Hategan, M; Hindmarsh, A; Prewett, S; Qian, W, 2015)
"Current treatments for esophageal cancer (EC) rely on tumor eradication by surgery or chemoradiotherapy."( Kang, Z; Li, S; Shi, J; Wang, L; Wang, Y; Wen, J; Zhou, Y, 2014)
"Patients with a locally advanced esophageal cancer and an homozygous GNAS 393C genotype do not benefit from platinum-based neoadjuvant chemoradiotherapy, indicating that these patients should be treated by alternative treatment strategies."( Alakus, H; Bollschweiler, E; Drebber, U; Eberz, PM; Frazer, KA; Harismendy, O; Hölscher, AH; Lowy, AM; Maus, M; Metzger, R; Mönig, SP; Siffert, W; Warnecke-Eberz, U, 2014)
"EC‑109 esophageal cancer cells were treated with varying concentrations of compounds 1-7 isolated from the plant as well as the ethanol extract of Artemisia dracunculus."( Hong, L; Ying, SH, 2015)
"The biomarker TP53 divides esophageal cancer patients into 2 categories with markedly different outcomes: patients with a normal TP53 marker status may experience notable benefits from neoadjuvant chemotherapy with cisplatin/fluorouracil, whereas those with a mutant TP53 marker status appear to be at risk for lack of response."( Ba-Ssalamah, A; Hejna, M; Kandioler, D; Kappel, S; Kührer, I; Mittlböck, M; Pluschnig, U; Schoppmann, SF; Wolf, B; Wrba, F; Zacherl, J; Zwrtek, R, 2014)
"Twenty patients with esophageal cancer confirmed pathologically were randomly divided into combined treatment (rh-endostatin+DP regimen) group and single chemotherapy group, 10 patients in each group, respectively."( Deng, WY; Li, N; Li, X; Luo, SX; Song, T, 2014)
"A total of 80 patients with esophageal cancer who underwent radical operations were selected as study patients and randomly divided into an observation group (treated with autologous blood transfusion) and control group (with homologous blood transfusion)."( Wang, YC; Xing, YL, 2014)
"Patients with esophageal cancer treated with esophagectomy by the same surgeon between 2004 and 2011 were reviewed."( Batirel, HF; Bilgi, Z; Celikel, CA; Ermerak, NO; Issaka, A; Kara, VH, 2015)
"Ninety oesophageal cancer patients, eligible for high dose (neo-adjuvant) (chemo)radiotherapy, were included."( Berveling, MJ; Beukema, JC; Groen, H; Hospers, GA; Langendijk, JA; Muijs, CT; Mul, VE; Plukker, JT; Pruim, J; van der Jagt, EJ; Woutersen, D, 2014)
"Neoadjuvant therapy for cancer of the esophagus or gastroesophageal (GE)-junction is well established."( Alexandersson von Döbeln, G; Kalman, S; Lund, M; Lundell, L; Nilsson, M; Tsai, JA; Winter, R, 2015)
"Patients with stage II, III, or IVA esophageal cancer were randomly allocated to either 2 cycles of ICT (oxaliplatin 130 mg/m(2) on day 1 and S1 at 40 mg/m(2) twice daily on days 1-14, every 3 weeks) followed by concurrent chemoradiotherapy (CCRT) (46 Gy, 2 Gy/d with oxaliplatin 130 mg/m(2) on days 1 and 21 and S1 30 mg/m(2) twice daily, 5 days per week during radiation therapy) and esophagectomy (arm A), or the same CCRT followed by esophagectomy without ICT (arm B)."( Cho, KJ; Jang, G; Jung, HY; Kim, HR; Kim, JH; Kim, JY; Kim, SB; Kim, YH; Lee, GH; Ryu, JS; Song, HY; Yoon, DH, 2015)
"Thirty-four patients with unresectable esophageal cancer were enrolled and received DNF therapy."( Fukuchi, M; Ieta, K; Inose, T; Kato, H; Kuwano, H; Miyazaki, T; Nakajima, M; Ojima, H; Saito, K; Sakai, M; Sano, A; Sohda, M; Suzuki, S; Tanaka, N; Yokobori, T, 2015)
"A man in his 60s was diagnosed with esophageal cancer (T3, N0, StageII) and treated with 5-fluorouracil and cisplatin as neoadjuvant chemotherapy (NAC)."( Akasaka, H; Hakamada, K; Ichinohe, D; Kimura, A; Kubo, N; Okano, K; Sakuraba, S; Shimada, T; Wajima, N; Yamana, D, 2014)
"Forty six patients with esophageal cancer who were treated with concurrent chemo-radiotherapy were enrolled."( Lu, WB; Ni, XC; Sun, SP; Sun, ZQ; Wang, J; Wang, JL; Yu, JP, 2015)
"Adults with esophageal cancer treated with chemotherapy consisting of 5-fluorouracil and cisplatin and 45-50 Gy radiation were recruited to the study."( Bowen, JM; Game, PA; Hussey, DJ; Irvine, T; Karapetis, CS; Keefe, DM; Kristaly, K; Smith, L; Tan, H; Thompson, SK; Tsykin, A; Watson, DI; White, I, 2015)
"In the West, where esophageal cancer occurs more frequently than gastric cancer, a phase III trial (the CROSS trial) demonstrated the efficacy of preoperative chemoradiotherapy using carboplatin plus paclitaxel for patients with esophageal or EGJ cancer."( Doki, Y; Kurokawa, Y; Miyata, H; Miyazaki, Y; Mori, M; Nakajima, K; Takahashi, T; Takiguchi, S; Yamasaki, M, 2015)
"Currently, esophageal cancer is rarely curable, and herein, a paclitaxel or 5-fluorouracil/esophageal stent combination (PTX or 5-FU/stent) was used to provide a new approach to treat this cancer."( Chen, W; Guo, S; Li, J; Liu, J; Shen, Y; Wang, Z; Wu, K, 2015)
"We report a case ofa 60-year old male esophageal cancer patient who was unable to take oral medication, but was successfully treated using a fentanyl citrate buccal tablet."( Baba, H; Fujimura, Y; Nakahara, O; Ohshima, S, 2015)
"Selected elderly patients with esophageal cancer and adequate functional status should not be excluded from CRT and may be able to tolerate the treatment with acceptable acute toxicities."( Bosset, JF; Créhange, G; Guimas, V; Maingon, P; Puyraveau, M; Roullet, B; Servagi-Vernat, S, 2015)
"During the treatment of esophageal cancer with curative intent, patients sometimes experience deep vein thrombosis, pulmonary embolism or a central venous catheter-associated thrombus."( Kato, F; Kawakubo, H; Kitagawa, Y; Matsuda, S; Omori, T; Takeuchi, H, 2016)
"Among 17 patients with advanced esophageal cancer, 2 patients made use of pemetrexed based regimens as first-line treatment,both of them got PR."( Huang, XE; Qian, T, 2015)
"Our current understanding of oesophageal cancer biology means that personalisation of multimodality therapy is based on accurate clinical staging, allied with patient co morbidities and patient preference."( Cosman, P; Das, A; Devadas, M; Lin, M; Merrett, N; Mittal, A; Wilson, R; Ziazaris, W, 2015)
"We collected29 advanced esophageal cancer patients who received albumin-bound paclitaxel-based chemotherapy fromJune 2009 to September 2013, and the efficacy and safety of the compound were evaluated."( Feng, JE; Mei, JF; Shen, B; Shi, L; Yuan, Y; Zhang, Y, 2015)
"Patients diagnosed with esophageal cancer were assessed for treatment response by comparing 2 F-FDG PET/CT scans, at baseline (PET 1) and 1 month after the end of induction chemoradiation (PET 2)."( Khong, PL; Tong, DK; Vardhanabhuti, V; Yuan, H, 2015)
"We assessed all patients with esophageal cancer of stages I-IV treated with definitive radiotherapy from June 2000 to March 2014."( Imae, T; Nakagawa, K; Ohtomo, K; Okuma, K; Omori, M; Takenaka, R; Yamashita, H, 2015)
"With the increased incidence of esophageal cancer, chemoradiotherapy continues to play an important role in the management of this disease."( Anbalagan, S; Biasoli, D; Hammond, EM; Leszczynska, KB; Mukherjee, S, 2015)
"In comparison with HET-1A cells, human esophageal cancer EC109 cells were treated with α-T at corresponding concentrations."( Jia, X; Li, Y; Liang, C; Sun, N; Yang, H, 2015)
"The survival rate associated with esophageal cancer is very poor due to diagnosis at advanced stages of disease and insensitivity to chemotherapy."( Gu, J; Hu, J; Mao, W; Sun, W; Sun, X; Wu, W; Xu, Y; Yu, X; Zhang, G; Zheng, Y, 2015)
"Taxane chemotherapy for esophageal cancer causes pneumonitis, not only by itself but also by radiation recall."( Endo, M; Fukutomi, A; Hamauchi, S; Kishida, Y; Machida, N; Onozawa, Y; Todaka, A; Tsushima, T; Yamazaki, K; Yasui, H; Yokota, T, 2018)
"We found that hesperetin induced esophageal cancer cells apoptosis in a concentration-dependent and time-dependent manner compared with the untreated cells."( Dong, W; Li, J; Liao, F; Wang, J; Wu, D; Zhang, J, 2016)
"We report a case of far-advanced esophageal cancer in which induction chemotherapy followed by chemoradiotherapy achieved complete remission."( Aga, K; Harada, H; Kaburagi, T; Koizumi, W; Matsumoto, H; Sakata, M; Seki, H; Shimada, A; Watanabe, H; Yasui, N, 2015)
"It was diagnosed to as metastatic esophageal cancer and treated with combination chemotherapy consisting of docetaxel (25 mg/m2, days 1, 8, 15) and cisplatin (25 mg/m2, days 1, 8, 15) in a 28-day cycle."( Hayashi, T; Horii, N; Inoue, H; Kimura, J; Kunisaki, C; Maezawa, Y; Makino, H; Masuda, M; Ohnishi, H; Ohshima, T; Rino, Y; Suzuki, Y; Takagawa, R; Tsuburaya, A; Yamamoto, J, 2015)
"Treatment of esophageal cancer cells with demethylating agent 5-Aza-dC led to increased miR-203a and miR-203b expression, confirming the epigenetic regulation of both miRNAs."( Dong, Z; Guo, W; Guo, X; Guo, Y; Kuang, G; Liang, J; Liu, Y; Shen, S, 2016)
"Sixty-one patients with advanced esophageal cancer who were scheduled to receive neoadjuvant chemotherapy were randomly allocated to 2 groups."( Akita, H; Asahara, T; Fujiwara, Y; Gotoh, K; Ishikawa, O; Kobayashi, S; Miyata, H; Miyoshi, N; Motoori, M; Nomoto, K; Noura, S; Ohue, M; Omori, T; Saito, T; Sakon, M; Sugimura, K; Takahashi, H; Yano, M, 2017)
"For these patients with metastatic esophageal cancer, chemotherapy is generally indicated."( Hayata, K; Iwahashi, M; Katsuda, M; Matsumura, S; Nakamori, M; Nakamura, M; Ojima, T; Yamaue, H, 2017)
"Successful treatment of oesophageal cancer is hampered by recurrent drug resistant disease."( Boersma, AW; McKenna, SL; Nyhan, MJ; O'Donovan, TR; Wiemer, EA, 2016)
"It is unknown whether restaging oesophageal cancer after neoadjuvant therapy with positron emission tomography-computed tomography (PET-CT) is more sensitive than contrast-enhanced CT for disease progression."( Bradley, KM; di Carlo, S; Findlay, JM; Franklin, JM; Gillies, RS; Gleeson, FV; Jones, GE; Maynard, ND; Middleton, MR; Teoh, EJ, 2016)
"Information about 406 consecutive esophageal cancer patients with resectable disease who underwent surgery with neoadjuvant chemotherapy consisting of cisplatin plus 5-fluorouracil or who underwent definitive CRT was reviewed."( Abe, T; Andoh, M; Kadowaki, S; Kodaira, T; Komori, A; Masuishi, T; Muro, K; Muto, M; Narita, Y; Niwa, Y; Nomura, M; Oze, I; Tachibana, H; Tajika, M; Taniguchi, H; Uemura, N; Ura, T, 2016)
"In advanced esophageal cancer patients, standard treatment involves chemoradiotherapy and surgery."( Imoto, H; Kiyozaki, H; Obitsu, T; Rikiyama, T; Saito, M; Takata, O; Taniyama, Y, 2016)
"The outcomes for patients with esophageal cancer (EC) underwent standard-dose radical radiotherapy were still disappointing."( Chang, D; Chen, C; Chen, J; Chen, Z; Guo, H; Guo, L; Huang, R; Li, D; Lin, K; Zhai, T; Zhang, W; Zhou, M, 2016)
"In the clinical setting for esophageal cancer, regimens that include nedaplatin might need to be treated as HEC."( Aiba, K; Baba, H; Baba, Y; Kitagawa, Y; Miyazaki, T; Nakajima, Y; Shibata, T; Shimada, H; Shimokawa, M; Tsuji, Y; Yamamoto, S; Yoshikawa, T, 2017)
"Although standard chemotherapy for esophageal cancer patients is fluorouracil and cisplatin, the prognosis is still unsatisfactory."( Matsuhashi, N; Okumura, N; Tanahashi, T; Tanaka, Y; Yamaguchi, K; Yoshida, K, 2016)
"In total, 33 patients with recurrent esophageal cancer after initial treatment (esophagectomy, chemotherapy, or chemoradiotherapy) were enrolled."( Abe, T; Hazama, S; Kanekiyo, S; Kitahara, M; Michihisa, I; Nagano, H; Nakajima, M; Nishiyama, M; Shindou, Y; Takeda, S; Yoshino, S, 2016)
"Patients with resectable oesophageal cancer are treated with neoadjuvant chemoradiotherapy (nCRT) followed by surgery within 3-8 weeks."( Creemers, GJ; Kathiravetpillai, N; Koëter, M; Luyer, MD; Nieuwenhuijzen, GA; Rutten, HJ; van der Sangen, MJ, 2016)
"Human BE and esophageal cancer cells were analyzed for miR‑193b expression and promoter methylation, with or without treatment with the hypomethylating agent 5‑azacytidine."( Chen, J; Gao, J; Gu, X; Liu, T; Lü, L; Mei, Z; Zeng, H, 2016)
"FDG-PET/CT images of patients with oesophageal cancer treated with dCRT (from 2003 to 2013) were reviewed to identify the anatomic distribution of FDG-avid LNs."( Bennink, RJ; Geijsen, ED; Hulshof, MC; Machiels, M; van Laarhoven, HW; van Os, RM; Wouterse, SJ, 2016)
"Forty patients with oesophageal cancer receiving cisplatin-based chemotherapy were assigned to either the ghrelin group (n=20), which received ghrelin (0."( Doki, Y; Hosoda, H; Kangawa, K; Kurokawa, Y; Makino, T; Miyata, H; Miyazaki, Y; Mori, M; Nakajima, K; Takahashi, T; Takiguchi, S; Yamasaki, M; Yanagimoto, Y, 2016)
"Responses of esophageal cancer to neoadjuvant therapy and patient prognosis are difficult to predict preoperatively."( Emi, M; Furukawa, T; Hamai, Y; Hihara, J; Kurokawa, T; Okada, M; Yamakita, I, 2016)
"EC109 and TE10 esophageal cancer cells were treated with 0, 10, 20 and 40 mM of PPARg agonist rosiglitazone (RGZ) for 24, 48, and 72 h, and the cell viability and apoptosis were detected using methyl thiazolyl tetrazolium (MTT) assay and Flow cytometric (FCM) analysis, respectively."( Liu, D; Qi, Y; Wu, K; Yang, Y; Zhang, C; Zhao, J; Zhao, S, 2016)
"A better understanding of how esophageal cancer (EC) cells reactivate primitive signaling to retain glucose metabolism under unfavorable conditions is essential for the development of therapeutic interventions to treat EC."( Hochwald, JS; Zhang, J, 2017)
"Patients with locally advanced esophageal cancer who are treated with trimodality therapy have a high recurrence rate."( Bueno, R; Choi, N; Cleary, JM; Donahue, DM; Enzinger, PC; Fidias, PM; Fuchs, CS; Gaissert, HA; Jaklitsch, MT; Kulke, MH; Lynch, TP; Mamon, HJ; Mentzer, SJ; Meyerhardt, JA; Swanson, RS; Szymonifka, J; Wain, J, 2016)
"Patients with stage IIA-IVA esophageal cancer received weekly cisplatin 30 mg/m(2) plus irinotecan 65 mg/m(2) on weeks 1, 2, 4, and 5 concurrently with 5040 cGy of radiation therapy."( Bueno, R; Choi, N; Cleary, JM; Donahue, DM; Enzinger, PC; Fidias, PM; Fuchs, CS; Gaissert, HA; Jaklitsch, MT; Kulke, MH; Lynch, TP; Mamon, HJ; Mentzer, SJ; Meyerhardt, JA; Swanson, RS; Szymonifka, J; Wain, J, 2016)
"Radiation therapy (RT) for esophageal cancer often results in unintended radiation doses delivered to the heart owing to anatomic proximity."( Bennion, NR; Bhirud, AR; Denniston, KA; Gharzai, L; Lin, C; Verma, V, 2016)
"Most solid tumours, including oesophageal cancer, contain hypoxic regions that are more resistant to chemoradiotherapy."( Berbée, M; Claessens, A; Dubois, LJ; Erdkamp, FL; Lambin, P; Larue, RT; Nap, M; Panth, KM; Peeters, SG; Schreurs, WM; Sosef, MN; Van De Voorde, L; van Elmpt, WJ; Warmerdam, FA, 2016)
"For patients with esophageal cancer who received neoadjuvant chemoradiation, pretreatment and posttreatment FDG PET parameters did not correlate with pCR or OS."( Arnett, ALH; Haddock, MG; Hallemeier, CL; James, SE; Macintosh, EM; Merrell, KW; Nathan, MA; Neben Wittich, MA; Ravi, K; Shen, KR, 2017)
"Twenty esophageal cancer patients receiving chemotherapy with 5-fluorouracil plus cisplatin were assigned randomly to one of the following two groups: (1) receiving elemental diet with Elental (one pack per day) for 14 days and (2) not receiving Elental during chemotherapy."( Hoshino, A; Kawada, K; Kawano, T; Miyawaki, Y; Nagai, K; Nakajima, Y; Nishikage, T; Okada, T; Ryotokuji, T; Tokairin, Y, 2017)
"Neoadjuvant chemotherapy(NAC)for esophageal cancer is standard in Japan."( Katayanagi, S; Kawachi, S; Makuuchi, Y; Osakabe, H; Shigoka, M; Sumi, T, 2016)
"50 patients with advanced esophageal cancer were treated with a continuous infusion of CF, 5-FU, and CDDP, and the short-term effects, adverse reactions, and survival periods after treatment were analyzed."( Cai, HX; Zhu, ZA; Zhu, ZQ, 2017)
"Sixty-five patients with an esophageal cancer treated with a combined chemo-radiation therapy were retrospectively included."( Desbordes, P; Di Fiore, F; Gardin, I; Gouel, P; Michel, P; Modzelewski, R; Pineau, P; Ruan, S; Vauclin, S; Vera, P, 2017)
"Patients with nonmetastatic esophageal cancer not suitable for surgery can be treated with definitive chemoradiotherapy with curative intent."( Fiocco, M; Grootenboers, DA; Marijnen, CA; Neelis, KJ; Peters, FP; Slingerland, M; van Ruler, MA; Vulink, AJ, 2017)
"Fifty-seven patients with esophageal cancer invading the trachea/bronchus or aorta who underwent induction therapy followed by surgery were enrolled."( Ho, MJ; Kobayashi, S; Miyata, H; Ohue, M; Omori, T; Sakon, M; Sugimura, K; Takahashi, H; Yanagimoto, Y; Yano, M, 2017)
"For resectable advanced esophageal cancer, a transthoracic esophagectomy following preoperative treatment is recognized as one of the standard treatments."( Fukuda, K; Kawakubo, H; Kitagawa, Y; Matsuda, S; Nakamura, R; Suda, K; Takeuchi, H; Wada, N, 2017)
"Long-term outcomes of older esophageal cancer patients (70 y and above) selected for treatment with neoadjuvant chemoradiotherapy followed by surgery or definitive chemoradiotherapy were comparable with the outcomes of their younger counterparts."( Aleman, BMP; Grootscholten, C; Sikorska, K; Snaebjornsson, P; van der Kaaij, RT; van Dieren, JM; van Sandick, JW; van Werkhoven, E; Voncken, FEM, 2018)
"To diagnose esophageal cancer at an earlier stage, and to improve the effect of anticancer therapy would improve the therapeutic efficacy."( Du, N; Li, X; Liang, R; Liu, J; Pang, Y; Ren, H; Sun, X; Tang, SC; Xu, C; Zhang, B; Zhang, J; Zhang, Y, 2017)
"After treatment of Eca109/ABCG2 (an esophageal cancer multidrug resistance cell line) cells with adriamycin (ADM) combined with EGCG for 24h, the cellular apoptosis, mitochondrial membrane potential, ADM concentration in cells and ABCG2 protein expression were detected by flow cytometry."( Ju, Y; Liu, L; Wang, J; Zhou, R, 2017)
"However, its utility in advanced esophageal cancer patients who receive radical esophagectomy with two- or three-field lymph node dissection with perioperative steroid therapy and enhanced recovery after surgery (ERAS) care is unclear."( Aoyama, T; Cho, H; Hayashi, T; Kano, K; Maezawa, Y; Masuda, M; Nakajima, T; Ogata, T; Oshima, T; Rino, Y; Sato, T; Yamada, T; Yoshikawa, T, 2017)
"A 65-year-old woman ofesophageal cancer received preoperative chemotherapy, and developed EFR before operation."( Fujiwara, T; Komoto, S; Maeda, N; Matsumi, Y; Ninomiya, T; Noma, K; Shirakawa, Y; Tanabe, S, 2017)
"Researchers often use murine models of esophageal cancer to evaluate novel therapies prior to clinical protocol treatment."( Hassan, MS; von Holzen, U, 2018)
"Twenty esophageal cancer patients treated with chemoradiation followed by surgery were prospectively enrolled."( Carter, BW; Fang, P; Fellman, BM; Hobbs, BP; Lin, SH; Ma, J; Mawlawi, O; Moreno, AC; Musall, BC; Son, JB, 2018)
"A total of 105 patients with esophageal cancer will swallowed meglumine diatrizoate and underwent a radiographic examination weekly during radiotherapy, medical personnel observed the esophageal lesions to determine whether an esophageal fistula formed."( Du, X; Fan, L; Geng, L; Hu, H; Li, M; Liao, D; Ma, Y; Wu, R; Xiang, M; Zhao, Y; Zhao, Z, 2018)
"TJ-100 treatment after esophageal cancer resection has the effects of prompting the recovery of gastrointestinal motility and minimizing body weight loss, and it might suppress the excess inflammatory reaction related to surgery."( Fujiwara, S; Furukita, Y; Goto, M; Inoue, S; Minato, T; Miyoshi, T; Nishino, T; Seike, J; Takechi, H; Takizawa, H; Tangoku, A; Toba, H; Yamai, H; Yamamoto, Y; Yoshida, M; Yoshida, T; Yuasa, Y, 2018)
"DCF-R treatment for advanced cervical esophageal cancer could be completed by the careful administration; although a strong blood toxicity might occur, this treatment may provide the chance to obtain favorable prognosis with larynx preservation."( Heishi, T; Ishida, H; Ito, K; Kamei, T; Konno-Kumagai, T; Maruyama, S; Okamoto, H; Onodera, Y; Sakurai, T; Sato, C; Taniyama, Y; Teshima, J, 2018)
"Of 326 patients with esophageal cancer, 189 received GFO administration (GFO group) and 137 did not (control group)."( Abe, T; An, B; Higaki, E; Hosoi, T; Kawai, R; Kawakami, J; Saito, T; Shimizu, Y; Uemura, N, 2019)
"We evaluated esophageal cancer patients treated between 2006 and 2014 with preoperative IMRT chemoradiation to a dose of 50."( Abuodeh, Y; Almhanna, K; Fontaine, JP; Frakes, JM; Hoffe, SE; Meredith, KL; Naghavi, AO; Pimiento, JM; Shridhar, R; Venkat, PS, 2017)
"From 2012 to 2016, 26 patients with esophageal cancer underwent pretreatment and intratreatment PET scans during chemoradiotherapy followed by surgery."( Ackerson, BG; Cui, Y; Czito, BG; Hong, JC; Marin, D; Palta, M; Rushing, CN; Tandberg, DJ; Willett, CW; Zhang, X, 2018)
"The inhibition of esophageal cancer growth by targeting SLC1A5 could, therefore, be used as a preoperative therapy for esophageal cancer."( Ca, D; Jiang, N; Lin, J; Pan, Q; Peng, Z; Wu, P; Xiao, H; Yang, T; Zhang, L, 2018)
"In patients with esophageal cancer, MTV and TLG derived from pretreatment F-FDG PET are significant prognostic factors."( Han, S; Kim, YJ; Lee, JJ; Suh, CH; Woo, S, 2018)
"The current treatment approaches for esophageal cancer are associated with poor survival, and there are ongoing efforts to find new and more effective therapeutic strategies."( Akhavan Rezayat, K; Avan, A; Fanipakdel, A; Ferns, GA; Gholami, A; Hosseini, S; Javadinia, SA; Joudi Mashhad, M; Taghizadeh Kermani, A; Zardadi, M, 2019)
"The proportion of elderly patients in esophageal cancer is now growing, but there is a lack of evidence in term of treatment standard for this group of patients, which is what we aim to obtain through this prospective phase III study."( Chang, X; Chen, J; Deng, L; Ge, X; Han, C; Li, C; Liang, J; Lin, Y; Ni, W; Pang, Q; Sun, X; Wang, L; Wang, P; Wang, W; Wang, X; Xiao, Z; Zhang, W; Zhao, Y; Zhou, Z, 2019)
"Perforation of esophageal cancer solely due to preoperative chemotherapy is extremely rare, but can be associated with pyothorax and can be difficult to treat."( Doki, Y; Kobayashi, T; Makino, T; Mori, M; Tanaka, K; Yamasaki, M, 2019)
"The conventional therapy for esophageal cancer is radiotherapy, although its effect is highly limited by the resistance of esophageal cancer cells."( Jiao, GH; Qiu, ZH; Zhang, HH; Zhang, WW, 2019)
"Among 937 patients with esophageal cancer at Toranomon Hospital between January 2011 and December 2018, 92 who underwent the DCF regimen as initial treatment were selected."( Ohkura, Y; Udagawa, H; Ueno, M, 2019)
"We report the case of a long-term esophageal cancer survivor treated by esophageal bypass operation for ERF after chemoradiotherapy (CRT)."( Emi, M; Hamai, Y; Ibuki, Y; Miyata, Y; Ohsawa, M; Okada, M, 2019)
"Dysphagia is a major symptom of esophageal cancer (EC) that significantly affects patient quality of life; however, little is known regarding its clinical impact on the treatment course in patients with EC."( Doki, Y; Hagi, T; Kimura, Y; Makino, T; Mori, M; Motoori, M; Nishida, N; Sakai, D; Satoh, T; Tanaka, K; Yamasaki, M, 2019)
"Background Esophageal cancer is a very common malignant tumor in China, especially esophageal squamous cell carcinoma (ESCC), but there is currently no effective treatment for patients after first-line chemotherapy failure."( Lei, J; Song, X; Wang, Y; Yu, J; Zhang, C; Zhang, N; Zhang, S; Zhao, J, 2020)
"for this purpose, Esophageal cancer cell (YM1) derived spheres were treated in vitro with OPE, NR, Dox, Dox in combination with OPE or NR."( Asadi, J; Ghasemnejad, A; Khosravi, A; Samadi, F; Tajaldini, M, 2020)
"Locally advanced esophageal cancer (EC) invading surrounding organs (T4b) is difficult to treat."( Fujiwara, T; Hashimoto, M; Katsui, K; Maeda, N; Nishizaki, M; Noma, K; Sakurama, K; Shirakawa, Y; Tanabe, S, 2020)
"The optimal dose in esophageal cancer patients treated with definitive chemoradiation (CRT) remains debated."( Carrère, N; Dalmasso, C; Guimbaud, R; Izar, F; Lusque, A; Modesto, A; Moyal, E; Rives, M; Vieillevigne, L, 2020)
"Patients with esophageal cancer treated with dCRT between January 2004 and November 2016 were included in this retrospective analysis."( Ishikura, S; Kondo, T; Miyakawa, A; Murai, T; Ozawa, Y; Shibamoto, Y; Sugie, C; Yanagi, T, 2020)
"Chemotherapy resistance of esophageal cancer is a key factor affecting the postoperative treatment of esophageal cancer."( Huang, X; Ma, X; Shi, S; Zhang, Q; Zhu, X, 2020)
"Among patients with esophageal cancer who received treatment with curative intention, cisplatin-fluorouracil was associated with better survival compared to carboplatin-fluorouracil, while patients with gastroesophageal junction cancer who were treated with cisplatin-fluorouracil had worse survival compared to fluorouracil-oxaliplatin."( Ebrahim, F; Ekheden, I; Henriksson, R; Ólafsdóttir, H; Raaschou, P; Wettermark, B; Ye, W, 2020)
"Patients with oesophageal cancer undergoing neoadjuvant chemoradiotherapy and surgery are at substantial risk of thromboembolic and bleeding events throughout all stages of treatment."( Büller, HR; Hovenkamp, A; Hulshof, MCCM; Kamphuisen, PW; Middeldorp, S; Mulder, FI; van Berge Henegouwen, MI; van Es, N; van Laarhoven, HWM, 2020)
"Unresectable esophageal cancer harbors high mortality despite chemoradiotherapy."( Chang, YC; Chao, YK; Chen, PJ; Ho, AT; Hsieh, JC; Hung, TM; Lee, CH; Pai, PC; Tseng, CK; Yang, CK; Yap, WK, 2020)
"The patient was a 71-year-old man with esophageal cancer who was referred to the oncology outpatient clinic for evaluation to determine the treatment plan."( Ishida, M; Onishi, H; Sato, I; Yoshioka, A, 2021)
"Patients with locally advanced oesophageal cancer who were treated with nCRT and oesophagectomy from July 2010 to February 2017 were analysed."( Ahn, MJ; Choi, JY; Lee, J; Lim, SW; Oh, D; Park, K; Shim, YM; Sun, JM; Zo, JI, 2020)
"Patients diagnosed with resectable oesophageal cancer who underwent neoadjuvant therapy should not be exempt from surgery based on PET-CT results."( Ahn, MJ; Choi, JY; Lee, J; Lim, SW; Oh, D; Park, K; Shim, YM; Sun, JM; Zo, JI, 2020)
"Patients with advanced esophageal cancer have a poor prognosis and limited treatment options after first-line chemotherapy."( Adenis, A; Al-Rajabi, R; Bennouna, J; Bhagia, P; Chen, J; de la Fouchardiere, C; Doi, T; Enzinger, P; Ferreira, P; Francois, E; Girotto, G; Hsu, CH; Kang, SP; Kato, K; Kim, SB; Kojima, T; Lee, SH; Lordick, F; Metges, JP; Moriwaki, T; Muro, K; Qin, SK; Senellart, H; Shah, MA; Shen, L; Suryawanshi, S; Wang, R, 2020)
"There were 291 esophageal cancer patients who received neoadjuvant/definitive chemoradiation therapy."( Farrugia, MK; Flaherty, L; Ma, SJ; Mattson, DM; Repasky, EA; Singh, AK, 2020)
"EGFR CNG in gastroesophageal cancer patients was associated with improved overall survival following fluoropyrimidine/platinum chemotherapy."( Baxter, M; Challapalli, P; Clark, C; Collinson, D; Iannetta, J; Meemanage, M; Miedzybrodzka, Z; Murray, G; Petty, RD; Spender, LC; Turbitt, J; Walsh, S, 2021)
"Definitive chemoradiotherapy(CRT)for esophageal cancer is the standard treatment and alternative to surgery."( Asagi, A; Hamamoto, Y; Hasebe, A; Hino, K; Hori, S; Inoue, T; Kajiwara, T; Kataoka, M; Nadano, S; Nakasya, A; Nishide, N; Nishina, T; Sakaguchi, C; Tanimizu, M; Terao, T; Yoshimatsu, M, 2020)
"A cohort of 113 patients with esophageal cancer who performed 18F-FDG PET/CT preneoadjuvant therapy was assessed."( Albenda, DG; Buchpiguel, CA; Cecconello, I; Duarte, PS; Junior, UR; Sallum, RAA; Takeda, FR; Tustumi, F, 2021)
"In patients with advanced esophageal cancer, PET/CT has a significant impact on clinical management by improving the selection of individualized treatment strategies and avoiding additional diagnostic procedures."( Gani, C; Gatidis, S; la Fougère, C; Nikolaou, K; Pfannenberg, C; Reinert, CP; Sekler, J, 2021)
"Gastro-oesophageal cancers (GEC) are resistant to therapy and lead to poor prognosis."( Ajani, JA; Bhutani, M; Chen, Q; Correa, A; Estrella, JS; Gan, B; Hofstetter, WL; Huo, L; Jin, J; Johnson, RL; Lee, JH; Lei, G; Li, CY; Li, Y; Liu, B; Ma, L; Pizzi, MP; Scott, A; Shanbhag, N; Song, S; Wang, Y; Wei, S; Weston, B; Xiao, L, 2021)
"Patients with proximal esophageal cancer treated with CRT between 2004 and 2014 in 11 centers in the Netherlands were included."( Blom, GJ; Bogers, JA; Bouwense, SAW; Braam, PM; de Jong, MA; de Vos-Geelen, J; Geurts, SME; Hoebers, FJP; Jeene, PM; Kasperts, N; Muijs, CT; Nieuwenhuijzen, GAP; Rozema, T; Tjan-Heijnen, VCG; Valkenburg-van Iersel, LBJ; Voncken, FEM, 2021)
"To compare the chemoradiotherapy for esophageal cancer followed by surgery study (CROSS) and continuous infusion 5-FU, leucovorin, oxaliplatin, and docetaxel (FLOT) protocols administered in distal esophageal and gastroesophageal junction (GEJ) tumors in terms of effectiveness and toxicity."( Ates, O; Cakmak Oksuzoglu, OB; Karadag, I; Karakaya, S, 2021)
"The human oesophageal cancer cell line TE-1 was treated with the combination of EPA and CDDP."( Higashida, M; Hirai, T; Kubota, H; Matsumoto, H; Miyake, S; Ogo, A; Teramoto, F; Ueno, T, 2021)
"Chemoradiotherapy for Esophageal cancer followed by Surgery (CROSS regimen) is standard of care for locally-advanced esophageal cancer."( Cooper, L; De León, LE; Dezube, AR; Dumontier, C; Enzinger, P; Frain, LN; Jaklitsch, MT; Kucukak, S; Mamon, H; Mazzola, E; Wee, JO, 2021)
"Human esophageal cancer cell line Eca109 was treated with 5 μg/mL or 10 μg/mL of quercetin."( Cheng, D; Li, CL; Liu, KD; Liu, Y; Sun, ZQ; Xu, QQ, 2021)
"In this study, we treated esophageal cancer (EC) cell lines, TE1 and KYSE450 with coptisine (COP) and investigated the biological effects of COP in EC cells."( Chen, X; Liu, C; Qu, S; Wen, X; Yang, Y; Zhang, X, 2021)
"We reviewed 52 patients with esophageal cancer who were treated with the first tPDT at Kyoto University Hospital between October 2015 and April 2020."( Amanuma, Y; Higuchi, H; Hirohashi, K; Horimatsu, T; Mitani, Y; Muto, M; Ohashi, S; Tamaoki, M; Yokoyama, A; Yoshioka, M, 2021)
"The Neoadjuvant Chemoradiotherapy for Esophageal Cancer 5010 study was a multicenter open-label randomized phase 3 clinical trial that enrolled patients between June 1, 2007, and December 31, 2014."( Chen, B; Chen, Y; Chen, Z; Fang, W; Fu, J; Guo, X; Han, Y; Kong, M; Li, Q; Li, T; Lin, T; Liu, H; Liu, M; Mao, T; Mao, W; Pang, Q; Wang, G; Wang, J; Xiang, J; Yang, H; Yu, Z; Zhang, X; Zheng, X; Zhu, C, 2021)
"First-line therapy for advanced oesophageal cancer is currently limited to fluoropyrimidine plus platinum-based chemotherapy."( Adenis, A; Antunes, L; Bhagia, P; Cho, BC; Doi, T; Enzinger, P; Fountzilas, C; Goekkurt, E; Hara, H; Kato, K; Kim, SB; Kojima, T; Li, SH; Li, Z; Liu, Q; Mansoor, W; Maqueda, MA; Metges, JP; Oliden, VC; Shah, MA; Shah, S; Shen, L; Sun, JM; Sunpaweravong, P; Tsuji, A, 2021)
"Although cure rates in esophageal cancer (EC) have improved since the introduction of neoadjuvant chemoradiation (nCRT), evidence for treatment-related cardiac toxicity is growing, of which the exact mechanisms remain unknown."( Beukema, JC; de Groot, C; Langendijk, JA; Muijs, CT; Plukker, JTM; Prakken, NHJ; van Luijk, P; van Melle, JP; Vliegenthart, R, 2022)
"In preoperative chemotherapy for esophageal cancer, the incidence of hematological toxicity was significantly higher in patients with low skeletal muscle mass."( Fujii, H; Hatanaka, Y; Imai, T; Mase, J; Matsuhashi, N; Ojio, H; Okumura, N; Sato, Y; Suetsugu, T; Takahashi, T; Tanaka, Y; Yoshida, K, 2022)
"Here, we present a case of esophageal cancer that was treated with esophagectomy, chemotherapy, and radiation therapy and developed oligometastases of the foot after 8 years in remission."( Dadparvar, S; Posocco, D; Ricely, JM, 2022)
"Fifty-one patients with esophageal cancer treated with radiation who underwent pre- and post-treatment FDG-PET scans were retrospectively evaluated."( Castillo, E; Castillo, R; Goodman, KA; Jones, B; Miften, M; Olsen, J; Schefter, T; Vinogradskiy, Y; Zakem, SJ, 2023)
"For FDG PET/CT and CT undetectable esophageal cancer, incorporation of the endoscopic measurement with PET/CT might be a way for making radiotherapy plan."( Chang, JS; Chang, WL; Chiu, NT; Hsu, SW; Lin, FC, 2022)
"The standard of treatment for esophageal cancer with adjacent organ invasion (T4) has not been established."( Aoshika, T; Iino, M; Kamada, T; Kano, K; Katoh, H; Mizoguchi, N; Saito, S; Shima, S; Takakusagi, Y; Taniuchi, R; Tsuchida, K; Yoshida, D, 2022)
"Patients with esophageal cancer can develop distant metastases between the start of neoadjuvant chemoradiotherapy (nCRT) and planned surgery (ie, interval distant metastases)."( Bakker, AS; Haj Mohammad, N; Jairam, J; Kroese, TE; Meijer, GJ; Mook, S; Ruurda, JP; van der Horst, S; van Hillegersberg, R; van Rossum, PSN, 2022)
"However, patients with esophageal cancer and PD-L1 CPS ≥ 10 may gain the most LYs from initial PPF treatment."( Ding, D; Liu, K; Peng, L; Zhou, Y; Zhu, Y, 2022)
"In open esophagectomy for esophageal cancer, steroid administration is associated with attenuated postoperative inflammation and reduced complications."( Daiko, H; Fujii, Y; Ishiyama, K; Kanematsu, K; Kubo, K; Kurita, D; Oguma, J, 2022)
"Forty treatment-naive esophageal cancer patients were recruited and divided into two groups: the ICG and control groups."( Chen, C; Du, J; Xu, G; Yang, Z; Zheng, B, 2022)
"The 49-year male with oesophageal cancer presented with haematemesis and had received neo-adjuvant chemotherapy 3 weeks back."( Iftikhar, J; Saqib, M; Siddique, MZ; Yusuf, MA, 2022)
"The 70 esophageal cancer patients were divided into radiotherapy-sensitive and radiotherapy-insensitive groups according to the efficacy of radiotherapy, and the methylation status of DACH1 was compared between the two groups."( Gu, Z; Huang, J; Jiang, L; Wang, W; Xu, Y; Zhu, W, 2022)
"Surgery is the treatment of choice for esophageal cancer."( Kim, MJ; Lee, JE, 2022)
"As the preoperative examination of esophageal cancer has improved, the likelihood of finding diseases in other organs that require surgical treatment has also increased."( Huang, C; Li, K; Li, X; Liu, X; Sun, S; Wang, Z; Zhang, G, 2023)
"To test this hypothesis, we treated esophageal cancer cells with CAP while controlling the supply of glutamine."( Jing, X; Wang, T; Zhang, F; Zhao, W, 2023)
"In patients with esophageal cancer, muscle loss induced by neoadjuvant therapy before esophagectomy is correlated with poor prognosis."( Ebata, T; Fukaya, M; Miyata, K; Shimizu, D; Sugita, S, 2023)
"Patients with esophageal cancer who underwent neoadjuvant therapy before esophagectomy between 2009 and 2020 were investigated (n=132)."( Ebata, T; Fukaya, M; Miyata, K; Shimizu, D; Sugita, S, 2023)
"Additionally, human esophageal cancer cells were treated with formononetin, and the effects on the proliferation and cell cycle of esophageal cancer cells were assessed by the CCK-8 assay and flow cytometry."( Chen, L; Guo, LR; Jin, J; Li, S; Xing, D, 2023)
"Interestingly, patients with gastroesophageal cancer benefitted more from this therapy."( Brossart, P; Feldmann, G; Gonzalez-Carmona, MA; Jafari, A; Kalff, JC; Köksal, M; Lingohr, P; Mahn, R; Mańczak, A; Möhring, C; Monin, MB; Sadeghlar, F; Sarria, GR; Sommer, N; Strassburg, CP; Timotheou, A; Toma, M; Zhou, T, 2023)
"We report a case of esophageal cancer with consciousness disorder due to hyperammonemia during FP treatment with an examination of some of the relevant literature."( Chiba, T; Hayashi, M; Iseki, H; Matsui, T; Miura, T; Noguchi, N; Ryotokuji, T; Tsunemi, A; Yamasaki, Y; Yokosuka, T, 2023)
"Patients with advanced esophageal cancer carry poor prognoses; limited data exist to guide second-line therapy in the metastatic setting."( Benson, A; Burtness, BA; Catalano, P; Cohen, SJ; Crandall, TL; Dotan, E; Fisher, GA; Kumar, P; Lubner, SJ; Mitchell, EP; Mulcahy, MF; Stockton, S, 2023)
"Detection of residual oesophageal cancer after neoadjuvant chemoradiotherapy (nCRT) is important to guide treatment decisions regarding standard oesophagectomy or active surveillance."( Bennink, RJ; Beukinga, RJ; Chatterjee, A; Doukas, M; Lagarde, SM; Lambin, P; Noordzij, W; Plukker, JTM; Roef, MJ; Schreurs, W; Valkema, MJ; Valkema, R; van Klaveren, D; van Lanschot, JJB; Wijnhoven, BPL; Woodruff, HC, 2023)
"In patients with inoperable esophageal cancer receiving concurrent systemic therapy, adding liquid nitrogen spray cryotherapy was safe and associated with improvement in dysphagia and QoL without causing reflux."( Garcia, R; Gupta, D; Gupta, S; Jewett, E; Kachaamy, T; Kaul, V; Mohapatra, S; Munsey, R; Pannala, R; Pollard, K; Rojas-DeLeon, M; Shah, T; Sharma, N; Vashi, P; Zelt, C, 2023)
"We treated two human esophageal cancer cell lines, KYSE30 and KYSE960, with up to 10 µg/mL of propofol for 12-36 h."( Konishi, Y; Nishiwaki, K; Zhang, A; Zhou, R, 2023)
"Despite recent advances in the study of esophageal cancer, there has been only limited improvement in the treatment and prognosis."( Gao, Y; Sheng, G; Wang, T; Wu, H; Wu, J, 2023)

Research

Studies (9,949)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901466 (14.74)23.3326
1990's1376 (13.83)12.5806
2000's2390 (24.02)18.1394
2010's3489 (35.07)28.8240
2020's1228 (12.34)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low10
alpha-hydroxyglutarate0low10
protocatechuic acid0medium21
phosphoserine0low10
gamma-aminobutyric acid0medium21
aminolevulinic acid0medium526
5-hydroxytryptophan0low10
ethylene glycol0medium11
acetic acid0medium253
acetaldehyde0medium251
adenine0medium182
ammonium hydroxide0medium31
beta-alanine0low30
benzene0medium51
benzoic acid0low10
betaine0medium21
1-butanol0low20
butyric acid0low20
carbamates0low10
carbon monoxide0medium52
carnitine0medium52
catechol0low30
methane0medium42
choline0medium81
citric acid, anhydrous0medium11
chlorine0medium41
hydrochloric acid0low120
coumarin0low10
salicylic acid0low120
phloroglucinol0low10
gallic acid0low50
hydrogen sulfide0medium51
methylmalonic acid0low10
aminocaproic acid0low20
dibenzofuran0medium11
creatine0low30
cytosine0low50
lactic acid0low110
dimethyl sulfoxide0medium51
ethanolamine0low20
formaldehyde0low190
glycine0medium165
glycerol0medium42
glycolic acid0low10
hydrogen carbonate0low20
dalteparin0medium63
histamine0medium52
hydrogen0medium42
indoleacetic acid0low10
iodine0medium557
dihydroxyphenylalanine0low10
kynurenine0low10
pipecolic acid0low10
racemethionine0low10
pyruvaldehyde0low10
methanol0low80
phytic acid0medium51
inositol0low10
melatonin0medium122
croton oil0low30
nickel0medium152
niacinamide0medium141
niacin0medium145
nitrates0medium382
nitroxyl0medium22
nitrites0medium381
nitrous oxide0medium61
orotic acid0low10
palmitic acid0low10
pentachlorophenol0low10
phenylacetic acid0low10
phosphoenolpyruvate0low10
phosphorylcholine0low10
porphobilinogen0low10
propylene glycol0medium11
1-propanol0low10
propionic acid0medium11
pteridines0low30
putrescine0low10
pyrazinamide0low10
pyridoxal phosphate0low10
pyridoxine0low10
pyruvic acid0low40
thiosulfates0medium21
sarcosine0low10
selenic acid0low10
selenious acid0low10
sulfites0medium91
spermidine0medium31
spermine0low10
succinic acid0medium11
sulfuric acid0low10
sulfur dioxide0medium11
taurine0low20
thiamine0medium61
thymine0medium42
toluene0medium31
uracil0medium276
uric acid0medium51
urea0medium215
vanillin0medium11
vanilmandelic acid0low10
menthol0low30
1,2-dimethylhydrazine0low20
s,s'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea0low10
1,5-dihydroxyisoquinoline0low10
pk 111950low10
1-anilino-8-naphthalenesulfonate0low20
edelfosine0low10
pd 1730740low20
3-aminobenzamide0low10
3-methylcholanthrene0low10
4-aminopyridine0low10
phenytoin0low20
hydroxyindoleacetic acid0low30
5-methoxytryptamine0low10
oxyquinoline0medium11
aa 8610low10
acetaminophen0medium71
acetazolamide0low10
ethacridine0low10
albendazole0medium11
alendronate0low80
alfuzosin0low10
diatrizoic acid0low20
amifostine anhydrous0low50
theophylline0low40
amiodarone0low10
anastrozole0low10
antipyrine0low10
acetovanillone0low10
arecoline0low30
aspirin0medium1026
atenolol0low20
azathioprine0low50
baclofen0low20
bay-k-86440low10
benzethonium0low10
benzo(a)pyrene0medium121
benzocaine0low20
benzothiazide0medium11
benzyl isothiocyanate0low30
berberine0low60
bethanechol0low10
biperiden0low10
bisbenzimidazole0low10
bromhexine0low10
bupivacaine0medium21
caffeine0low60
verapamil0low40
candesartan0medium21
carbazilquinone0low10
carmofur0low20
carmustine0low60
celecoxib0medium3110
chlordiazepoxide0low10
chloroquine0medium81
chlorpromazine0low10
chlorpropamide0low10
ciglitazone0low10
cimetidine0low150
ciprofloxacin0low10
cisapride0medium41
citalopram0low10
clofazimine0low10
clonazepam0low20
clonidine0medium33
dantrolene0low10
dapi0low10
dapsone0low10
deferoxamine0low30
eflornithine0medium82
diazepam0medium53
diclofenac0medium21
dichlorvos0low10
pentetic acid0low60
3,3'-diindolylmethane0low10
diphenhydramine0medium22
diphenyleneiodonium0low10
dipyridamole0low10
disulfiram0low70
valproic acid0low30
racemetirosine0low30
domperidone0low30
donepezil0low10
emodin0medium21
erythrosine0medium31
etanidazole0medium11
ethacrynic acid0low10
ether0low10
ethoxyquin0low10
etidronate0low20
etilefrine0low30
fenofibrate0low10
fentanyl0medium168
fluconazole0medium51
flucytosine0low10
flumazenil0low10
flunitrazepam0low10
fluorouracil0medium1,856517
flurbiprofen0medium74
fp 830medium42
flutamide0low10
fosfosal0low10
furosemide0low30
fusaric acid0low10
gabexate0medium41
gentamicin0low10
glutaral0low10
gossypol0medium31
guaifenesin0low40
ha14-10low10
haloperidol0low30
halothane0low30
harmaline0low10
hexestrol0low10
hydroxychloroquine0low10
hydroxyurea0medium81
hypericin0low10
lidocaine0medium43
mephentermine0low10
ifosfamide0medium206
indomethacin0low110
iodixanol0low20
iohexol0medium71
iomeprol0low10
iopanoic acid0low10
iopromide0low40
ioversol0medium41
isoflurane0medium32
isoniazid0low30
2-propanol0low10
isoproterenol0low10
ketamine0medium22
ketoconazole0medium11
ketoprofen0medium11
ketorolac0low60
khellin0low10
lansoprazole0low60
lapachol0low10
beta-lapachone0low10
lidoflazine0low10
lomustine0medium51
loperamide0medium11
losartan0medium21
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one0low170
edaravone0medium11
mechlorethamine0medium41
memantine0medium11
vitamin k 30low10
meperidine0medium71
mephenytoin0medium11
mepivacaine0low10
mesalamine0low10
metformin0medium463
methadone0medium11
nocodazole0low10
methyl salicylate0medium11
methyl methanesulfonate0low30
metoclopramide0medium81
metoprolol0medium21
metronidazole0medium143
metyrapone0low20
mianserin0low20
midazolam0medium126
midodrine0low10
mirtazapine0low20
mitoxantrone0low10
entinostat0low50
ethylmaleimide0low10
apnea0low30
nafamostat0low10
activins0low80
nicardipine0low40
niclosamide0low30
nifedipine0low50
nimesulide0low70
nitrendipine0low10
nitroglycerin0medium31
5-nitro-2-(3-phenylpropylamino)benzoic acid0low10
n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide0low170
ofloxacin0medium11
omeprazole0medium547
ondansetron0medium21
osalmide0low10
oxonic acid0medium10226
oxethazaine0low10
oxyphenbutazone0medium11
aminosalicylic acid0low10
quinone0low10
pamidronate0low10
pargyline0low10
pd 1530350low20
pd 980590low70
phenacetin0low10
phenobarbital0medium41
phenolsulfonphthalein0medium11
phenoxybenzamine0low10
phenylbutazone0low10
pioglitazone0low10
piperazine0low10
potassium chloride0low10
potassium iodide0low10
procaine0low30
procarbazine0medium21
prochlorperazine0low10
proglumide0low10
propantheline0low40
propidium0low10
propofol0medium2310
propranolol0low30
protoporphyrin ix0medium151
pyrimethamine0medium11
1,2,5,8-tetrahydroxy anthraquinone0low10
rabeprazole0low60
resorcinol0low10
rofecoxib0low30
saccharin0low10
safrole0low20
secobarbital0low10
semustine0low20
sevoflurane0medium73
sulfadiazine0medium11
sodium fluoride0medium21
vorinostat0low30
succinylcholine0low10
sulconazole0low10
sulfasalazine0low20
sulforaphane0low30
suramin0low10
tegafur0medium14834
temozolomide0medium41
tetracaine0low10
thalidomide0medium73
thioridazine0low10
thiotepa0low60
thonzylamine0low10
ticlopidine0low20
tilorone0low30
nikethamide0medium11
tolazoline0low10
tolmetin0low20
n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine0low10
triclosan0medium21
trimetrexate0medium42
troglitazone0low40
urethane0low130
2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2h-tetrazolium hydroxide0low10
3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole0low20
zolpidem0low10
mitomycin0medium8522
prednisolone0low280
estriol0low20
sorbitol0medium31
thymidine0medium241
floxuridine0medium82
hydroxyproline0low10
thyroxine0medium91
dibenzylchlorethamine0low10
carbachol0low20
spironolactone0low10
penicillamine0low10
prednisone0medium273
estrone0low10
2-acetylaminofluorene0low30
penicillin g0low10
idoxuridine0medium31
triiodothyronine0low30
diethylnitrosamine0low550
methyldimethylaminoazobenzene0low10
carbon tetrachloride0low10
alanine0medium61
serine0low140
benz(a)anthracene0low10
4-nitroquinoline-1-oxide0low330
chloramphenicol0low10
aspartic acid0low10
glutamine0medium236
lysine0low150
ethinyl estradiol0low10
tubocurarine0low10
9,10-dimethyl-1,2-benzanthracene0low60
aminopyrine0low20
cephalothin0low10
uridine0low40
bromodeoxyuridine0low160
galactose0medium11
carbostyril0medium111
phenylephrine0low10
n-nitrosomorpholine0low20
edetic acid0low20
p-dimethylaminoazobenzene0low10
phenylethyl alcohol0low10
tyrosine0medium221
monomethylhydrazine0medium11
phlorhizin0low10
methicillin0low10
cloxacillin0low10
methylene blue0medium331
leucine0medium101
dimethylnitrosamine0low1970
androstenedione0low10
methionine0medium121
1,2-dipalmitoylphosphatidylcholine0low20
phenylalanine0low50
desoxycorticosterone0low10
colchicine0medium101
cytidine triphosphate0low20
cycloheximide0low20
egtazic acid0low10
chloroform0low20
dimethyl sulfone0low10
gliotoxin0low10
17-alpha-hydroxyprogesterone0low10
ampicillin0low30
cytarabine0low50
trifluridine0medium54
ornithine0medium22
asparagine0low20
histidine0medium51
1,1,1-trichloroethane0low10
valine0low30
threonine0low10
methandrostenolone0low10
chlorquinaldol0medium11
cordycepin0low10
tryptophan0low60
isoleucine0low20
arginine0medium216
ethane0low10
ethylene0medium11
acetonitrile0low10
methylene chloride0low10
carbon disulfide0low10
trichloroacetic acid0low10
perflutren0low20
triamcinolone acetonide0medium124
phencyclidine0medium132
tromethamine0low20
quinic acid0low10
isoprene0low120
trichloroethylene0low40
acrylamide0low20
acrylic acid0medium61
dichloroacetic acid0low10
bisphenol a0medium11
taurocholic acid0low50
rhodamine b0medium11
methylprednisolone0medium176
rotenone0low50
skimmianine0low10
n-nitrosodiphenylamine0low10
penicillin v0low10
xylitol0medium32
n-vinyl-2-pyrrolidinone0medium31
xanthone0low10
quinoxalines0medium62
1,2,3,4-tetrahydroisoquinoline0low10
quinoline0low10
2-naphthylamine0low20
tolonium chloride0low140
synephrine0low10
4-butyrolactone0low20
o-aminoazotoluene0low10
ethylbenzene0medium11
n-nitrosopiperidine0low130
quinuclidines0medium41
cyclamic acid0low10
pyridostigmine bromide0low10
4,4'-diaminodiphenylmethane0low10
n-methylbenzylamine0low50
betazole0low10
ethyl bromoacetate0medium11
caprolactam0medium11
propargyl bromide0low10
acrolein0low10
acrylonitrile0low10
hexylene glycol0low10
2-methylpentane0low10
vinyl acetate0low10
pentane0low10
pyrroles0medium254
thiophenes0medium145
isopropyl myristate0medium11
pentanal0low10
morpholine0low10
phenformin0low20
diethylhexyl phthalate0low10
framycetin0medium51
isoquinoline0low10
triethylamine0low10
sulfan blue0low10
pyrazolanthrone0low20
1,4-naphthoquinone0low10
diatrizoate meglumine0medium82
meglumine0medium31
iodohippuric acid0low10
2-naphthol0medium51
neozone0low10
shikimic acid0medium21
4-nitrosodimethylaniline0low30
citronellol0medium11
ethyl acetate0low20
diphenhydramine hydrochloride0low10
ditiocarb0low10
potassium cyanide0medium21
catechin0medium181
perylene0low10
benzo(b)fluoranthene0low10
chrysene0low10
quinazolines0medium9030
acridines0low40
indazoles0medium71
benzoxazoles0medium11
cyclopentane0medium41
isoxazoles0medium91
oxazoles0low30
thiazoles0medium273
pyrimidine0low10
pyrazines0medium162
calcium gluconate0low10
diiodotyrosine0low10
hydrazine0medium91
thiocyanate0low20
pirinitramide0medium11
aminophylline0low10
azacitidine0medium711
diazomethane0low10
cyanamide0low10
fluorometholone0low10
lithocholic acid0low10
nandrolone0medium51
thiazolidine-4-carboxylic acid0low20
hydantoins0medium11
n-pentyl nitrite0low10
chenodeoxycholic acid0low80
fusarium0low290
plumbagin0low20
cepharanthine0low20
emetine0low10
osthol0low10
thymoquinone0low10
indoline0low10
isomaltose0low10
alpha-aminopyridine0medium62
thiazolidines0low100
mustard gas0low10
oleanolic acid0low30
periplogenin0low10
hematoxylin0low140
podophyllotoxin0medium91
hesperidin0medium52
dihydrotestosterone0low10
luminol0medium11
gluconic acid0medium11
copper gluconate0medium11
azomycin0medium157
3',5'-dichloromethotrexate0medium11
perillyl alcohol0low10
muscone0medium11
malondialdehyde0medium81
eosine yellowish-(ys)0low120
gentian violet0low50
paeonol0low20
hematoporphyrin0medium354
congo red0low10
3-hydroxyflavone0medium61
diphenylamine0medium11
3-methylhexane0low10
allyl sulfide0low70
megestrol acetate0low10
glycopyrrolate0low10
methylurea0low10
n-methyl-n-nitrosoaniline0low40
n-ethyl-n-nitrosourethane0low30
nitrosomethylurethane0low70
acetylcysteine0medium102
n-nitroso(di-n-propyl)amine0low30
6-methyluracil0low20
c.i. 425100low40
glycochenodeoxycholic acid0low10
benzydamine0low10
erythromycin0medium52
dehydroepiandrosterone sulfate0low10
diisopropylamine dichloroacetate0low10
nitrosoguanidines0low40
2-piperidone0medium51
methylnitrosourea0low110
ethylnitrosourea0low30
levonorgestrel0medium21
calcium lactate0low10
naphthyl acetate0low10
ethyl gallate0low10
dibutylnitrosamine0low80
n-nitrosopyrrolidine0low120
n-nitrosoperhydroazepine0low20
nitrosobenzylmethylamine0low1780
deoxycytidine0medium15172
deoxyuridine0low10
ethambutol0low20
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diallyl disulfide0low40
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gemcitabine0medium3618
temoporfin0medium173
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valsartan0low10
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capecitabine0medium17876
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carbogen0low10
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glucose, (beta-d)-isomer0medium91
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thiazolyl blue0low90
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plerixafor0low10
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wr 10650low10
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2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine0low10
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paxilline0low40
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cv 39880low10
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stachydrine0low10
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ginsenoside rh20low10
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angiotensin ii, des-phe(8)-0low10
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antibiotic g 4180low10
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canertinib0low10
cinacalcet0low10
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jte 5220low10
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sb 2035800low30
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psyllium0low10
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aflatoxin b10low30
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n-(3-pyridylmethyl)adriamycin0low50
ramelteon0low10
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n,n-diamylnitrosamine0low10
nsc 748590low20
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nas0low10
solanine0low10
wortmannin0low50
2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one0low10
croton factor f10low10
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erianin0low10
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ritonavir0medium21
bardoxolone methyl0low10
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carboplatin0medium18664
lithium chloride0low40
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glycogen0low110
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glucosamine0low20
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oxytocin0low10
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quinidine0low10
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y 276320low30
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chalcone0low30
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gw96620low10
s 10330low10
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rg1080low10
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fumonisin b10medium311
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p50910low10
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linoleic acid0low50
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vitamin k semiquinone radical0low20
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thromboxane a20medium21
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8,11,14-eicosatrienoic acid0medium41
gossypetin0low10
quercetin 3-o-methyl ether0low10
furylfuramide0low10
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kaempferol0low20
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lipoxin a40low10
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genistein0low30
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diosmin0medium21
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myricetin0low10
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plantamajoside0low10
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menaquinone 60medium11
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fluticasone0medium21
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glycitein0low10
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casein kinase ii0low40
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ag-4900low20
bosutinib0low10
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su 112480medium93
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mitoguazone0medium102
fosbretabulin0medium11
lead0medium82
tin0low20
12-hydroxy-5,8,10,14-eicosatetraenoic acid0low10
15-hydroxy-5,8,11,13-eicosatetraenoic acid0low10
bay 11-70820low30
antimony0medium21
barium0medium161
aluminum0low40
strontium0medium41
bismuth0medium22
thallium0medium11
alternariol0low30
arsenic0medium161
indium0medium71
alternariol monomethyl ether0low40
lasalocid0low10
gallium0medium71
cefodizime0low20
sulfur0medium61
geldanamycin0low10
retinamide0medium55
puerarin0low10
ajoene0low20
enalapril0medium11
sinomenine0low20
fumarates0low10
cysteine0medium121
silicon0low30
indium0low10
phosphorus0medium132
boron0medium21
cefepime0medium11
ici 1185510low20
talaporfin0medium72
pregabalin0low10
fibroblast growth factor (1-10)0low10
tiotropium bromide0medium11
baohuoside i0low10
alpinumisoflavone0low20
isocoumarin nm-30low10
vx6800low10
carbocyanines0low30
25-hydroxyvitamin d 20low10
cefotaxime0medium11
ammonium sulfate0low10
ma-10medium43
monorden0low10
germanium0low20
selenium0medium636
radium0low260
palonosetron0medium11
dizocilpine maleate0medium11
sulphoraphene0low10
simethicone0medium11
fusarin c0low50
germacrone0low10
involucrin0low80
4-(carboethoxyphenyl)retinamide0low20
e 33300low10
pregna-4,17-diene-3,16-dione0low30
everolimus0medium115
hydroxysafflor yellow a0low10
u 753020low10
axitinib0medium11
n-(4-carboxyphenyl)retinamide0low20
tanespimycin0low50
beta-escin0low70
lactacystin0low10
peplomycin0medium363
butylscopolammonium bromide0low20
gadolinium dtpa0low100
morphinans0low20
barium sulfide0low10
fumagillin0low10
detorubicin0medium11
beta-elemene0low60
docosahexaenoyl-paclitaxel0medium11
panobinostat0low10
isoborneol0low10
gamma-glutamylvaline0low10
staurosporine0low10
bufalin0low30
shu 5080low10
bacteriochlorin0low10
taxane0medium143
9h-purine-9-propanamine, 6-amino-8-((6-iodo-1,3-benzodioxol-5-yl)thio)-n-(1-methylethyl)-0low10
chlorhexidine0low10
formazans0low40
s 17430medium72
3-aminopyridine-2-carboxaldehyde thiosemicarbazone0low10
ferrihydrite0medium11
amoxicillin-potassium clavulanate combination0low20
vidofludimus0low10
kb r79430low10
lu 28-1790low10
efatutazone0low10
sincalide0low100
licochalcone c0low10
ginsenoside m10low10
gambogic acid0low20
pentagastrin0low20
cabazitaxel0medium33
elisidepsin0medium11
knk 4370low10
mocetinostat0medium141
sc 2360low20
bleomycin a60low10
lipid a0medium11
4-methylene-2-octyl-5-oxofuran-3-carboxylic acid0low10
mart-1 antigen0low30
2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide0low10
thiocolchicoside0medium11
ginsenoside rg30medium11
sorbitan monooleate0medium11
rucaparib0medium11
tae2260low20
pasireotide0low10
s 56820medium11
zeolites0medium21
pitolisant0medium11
aq4n0medium11
aluminum oxide0medium21
osu 030120low10
pimavanserin0low10
masitinib0low10
18f-faza0low10
ly-21572990low20
oblongifolin c0low10
pazopanib0low20
sepantronium0low50
prasugrel hydrochloride0low10
bibw 29920low30
vitamin u0low10
gw 7993880low10
artenimol0medium71
trans-sodium crocetinate0low10
sotrastaurin0low10
saracatinib0medium31
2-acetylfuranonaphthoquinone0medium11
ngr peptide0low10
crenolanib0medium11
rabdocoetsin b0low10
ipragliflozin0low10
volasertib0low10
PB280low10
oxadiazoles0medium11
ucn 1028 c0low20
acebutolol0medium11
migrastatin0low10
lactulose0medium11
regorafenib0medium32
wp10660low10
epoxomicin0low10
nystatin a10low10
pirarubicin0low10
er-0865260low10
bi 25360low20
technetium tc 99m disofenin0low10
nutlin-3a0low30
nvp-aew5410low10
arq 1970medium11
lbw2420low10
pf 002998040medium11
pyrazolone0low10
dorsomorphin0low10
quisinostat0low10
capilliposide c0low10
carfilzomib0medium11
crizotinib0medium41
fostamatinib0low10
trametinib0low20
losartan potassium0medium124
ginsenoside ro0low10
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc0low30
2-(n-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose0low10
empagliflozin0medium11
calcimycin0medium21
dextrothyroxine0low20
indocyanine green0medium824
scopolamine hydrobromide0low20
cinobufagin0low10
dactolisib0low20
pituitrin0low80
podophyllin0low20
th 3020medium21
phytosterols0low20
clove0low20
acid phosphatase0low50
bleomycetin0medium42
7-n-(4-hydroxyphenyl)mitomycin c0low10
curcumol0low20
butaprost0low20
physalaemin0low10
jaw0low20
tosedostat0low10
cyanidin-3-o-beta-glucopyranoside0low10
nad0medium61
unbs 51620low10
cytochrome c-t0low150
melitten0low10
cholecystokinin0low30
motilin0low20
atrial natriuretic factor0low60
hes1 protein, human0low60
gastrins0medium432
glucagon0medium112
big gastrin0low10
beta-endorphin0medium54
thymosin beta(4)0low10
thymopoietin iii0low10
neuropeptide y0low20
tannins0low120
oligonucleotides0low110
glucagon-like peptide 10medium41
incretins0medium11
c-peptide0low20
ctce-99080low10
cellulose0medium43
endothelin-10medium31
phosphatidylcholines0low60
a-83-010low10
buparlisib0medium11
chlorophyll a0medium51
3-(3-(4-((pyridin-2-yloxy)methyl)benzyl)isoxazol-5-yl)pyridin-2-amine0medium11
pevonedistat0low30
dihydroceramide0low10
hoe 333420low40
jsh 230low10
sodium salicylate0low10
sphingosine kinase0low60
ubiquinone0medium31
cilastatin, imipenem drug combination0low10
calpain0low30
ginsenoside rh40low20
chitosan0medium31
icotinib0medium32
technetium tc 99m sestamibi0low50
15-deoxyprostaglandin j20low10
mesna0low20
sodium hypochlorite0low10
sodium bisulfite0low20
sodium lactate0medium11
sodium nitrite0low110
potassium bromate0medium11
ro13-99040low10
sodium pertechnetate tc 99m0low70
sodium ethylxanthate0low150
chiniofon0low10
olaparib0low30
lcl1610low10
cpi 6130low10
mln 82370medium31
snx 21120low30
lde2250low10
gdc 04490low10
carcinomedin0low10
pci 327650low20
intrinsic factor0medium11
oxymatrine0low10
niraparib0medium21
az 5050low10
mk 22060medium22
suvorexant0low10
cc-1220medium11
navitoclax0low20
bi d18700low10
cardiovascular agents0low20
defactinib0low10
mannans0medium11
gsk 21264580low10
ixazomib0low10
11,12-epoxy-5,8,14-eicosatrienoic acid0low10
fumonisin b40low10
plx40320medium11
gsk 13630890low30
glycolipids0medium61
piperidines0medium457
bryostatin 10medium43
thymosin0medium41
interleukin-80medium6411
ribociclib0low10
mme0medium11
apatinib0medium2010
gx 15-0700low40
hydroxocobalamin0low10
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine0medium11
exenatide0low10
endrin0medium11
gsk 23344700low10
nvp-bsk8050low10
afuresertib0low10
gyy 41370low10
gsk525762a0low10
technetium tc 99m gluceptate0low10
tubastatin a0low10
azd45470low20
azd81860low10
apr-2460low20
vasoactive intestinal peptide0low50
natriuretic peptide, brain0medium103
acy-12150low10
heme0medium71
gsk26561570low10
ascorbic acid0medium637
tetracycline0medium81
minocycline0low10
dicumarol0low20
piroxicam0low20
mobic0medium11
warfarin0medium81
gimeracil0medium32
teriflunomide0medium11
s 1 (combination)0medium9925
abt-3330low10
byl7190medium31
nk 1210low10
epidermal growth factor0low760
pf 35126760medium11
zhengguangmycin0medium81
gastrin-releasing peptide0low10
calca protein, human0medium31
bismuth oxybromide0medium11
transforming growth factor beta0medium952
phytoestrogens0medium21
okadaic acid0low10
sybr green i0low10
bms-8339230low10
gkt1378310low20
vx-9700low30
epz-64380low10
longikaurin a0low10
acp-1960low10
kiss1 protein, human0low40
verdinexor0low10
agar0low50
cb-8390low10
technetium tc 99m lidofenin0low10
gsk-j40low10
hirudin0medium11
imetelstat0low20
glutaminase0low40
cyclin d10medium2261
ginsenoside rk30low10
technetium tc 99m sulfur colloid0low70
phthalocyanine0low30
g(m3) ganglioside0low10
benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone0low30
lewis x antigen0low50
calpastatin0low20
angiotensin i0low10
lly-5070low10
hyaluronoglucosaminidase0low10
adrenomedullin0medium11
epoetin alfa0medium32
nct-5010low10
fumonisin b30medium41
lipofectamine0low10
ganoderic acid d0low10
neferine0low10
oridonin0low60
t-2 toxin0low10
vitamin b 120medium152
ferric ammonium citrate0low10
oblimersen0medium11
sermorelin0low10
transforming growth factor alpha0medium301
cyclosporine0low30
flavin mononucleotide0low30
silybin0low10
apicidin0low10
peptide yy0low10
lactoferrin0low20
catalpol0medium11
alpha-solanine0low10
gallium ga 68 dotatate0low10
orabase0medium52
technetium tc 99m medronate0medium141
technetium tc-99m tetrofosmin0low30
sodium morrhuate0low40
apyrase0low10
thromboplastin0low50
muramidase0low20
nedaplatin0medium12729
chondroitin sulfates0low20
exudates0medium131
acyclovir0low20
levoleucovorin0medium17288
cyclic gmp0low10
deoxyguanosine0low190
guanosine monophosphate0low10
guanosine triphosphate0low10
guanine0medium305
guanosine0low40
inosine0medium31
folic acid0medium512
3-methyladenine0low60
7-methylguanine0low30
neopterin0low10
rifampin0low20
clozapine0low10
dacarbazine0medium161
ganciclovir0low90
olanzapine0low10
raltitrexed0medium63
8-azaxanthine0low10
allopurinol0medium62
xanthopterin0low10
guanosine 5'-monophosphorothioate0low10
8-hydroxyguanosine0low20
pemetrexed0medium127
cytarabine0low10
aprepitant0medium83
fosaprepitant0medium31
8-hydroxyguanine0low40
trypan blue0low10
nintedanib0medium11
methylnitronitrosoguanidine0low230
8-hydroxy-2'-deoxyguanosine0low150
8-methylguanosine0low10
cytidylyl-3'-5'-guanosine0low10
enng0low70
sta 90900medium11
pp2420low20
7-methylguanosine triphosphate0low10
ed 1100low10
temoporfin0low10
alcian blue0low10
conglobatin0low20
eye0low10
chromomycin a30low10
n-glycolylneuraminyllactosylceramide0low10
acetylcellulose0medium11
pseudolaric acid b0low10
concanavalin a0medium92
trypsinogen0low10
metallothionein0low200
phosphorus radioisotopes0low40
leptin0medium262
pyrimidinones0low20
sinoporphyrin sodium0low10
phenanthrenes0low20

Protein Targets (4,353)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE13200132
Chain A, Ferritin light chain10900109
TDP1 protein38500385
Microtubule-associated protein tau19600197
aldehyde dehydrogenase 1 family, member A125900259
regulator of G-protein signaling 412600126
glucocerebrosidase600060
euchromatic histone-lysine N-methyltransferase 230700307
vitamin D3 receptor isoform VDRA14800148
survival motor neuron protein isoform d13700137
Cytochrome P450 3A401125131
Cytochrome P450 2C9 081391
Short transient receptor potential channel 60101
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A930093
Chain A, RNA-directed RNA polymerase NS50404
acid sphingomyelinase260026
thioredoxin reductase18800188
USP1 protein, partial19000190
importin subunit beta-1 isoform 1450045
flap endonuclease 110300103
serine/threonine-protein kinase PLK1390039
snurportin-1450045
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1630063
GTP-binding nuclear protein Ran isoform 1290029
DNA polymerase eta isoform 1530053
DNA polymerase iota isoform a (long)14900149
urokinase-type plasminogen activator precursor720072
plasminogen precursor720072
urokinase plasminogen activator surface receptor precursor720072
geminin33000330
DNA polymerase kappa isoform 110900109
fibroblast growth factor 22 isoform 1 precursor0002
Mitogen-activated protein kinase 13042327
Beta-lactamase0808
Transthyretin081224
Fatty acid-binding protein, intestinal08311
Fatty acid-binding protein, adipocyte08311
Cyclin-A2013014
Cannabinoid receptor 10527
Cyclin-dependent kinase 20285484
Choline O-acetyltransferase0202
Mitogen-activated protein kinase 12042529
Guanine nucleotide-binding protein G410041
Fatty acid-binding protein 50527
Fatty acid-binding protein 50022
Mitogen-activated protein kinase 11045155
Mitogen-activated protein kinase 140305585
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE18900189
glucocorticoid receptor [Homo sapiens]28500285
farnesoid X nuclear receptor19300193
estrogen nuclear receptor alpha44500445
Voltage-dependent calcium channel gamma-2 subunit18300183
Cellular tumor antigen p5329130294
Glutamate receptor 219542201
Choline O-acetyltransferase 0507
Chain A, Cruzipain750075
Platelet-activating factor receptor4308
Inositol monophosphatase 1710071
RAR-related orphan receptor gamma29800298
aryl hydrocarbon receptor16300163
thyroid stimulating hormone receptor15400154
estrogen-related nuclear receptor alpha36200362
nuclear factor erythroid 2-related factor 2 isoform 129800298
GLI family zinc finger 330500305
AR protein37500375
retinoic acid nuclear receptor alpha variant 130500305
peroxisome proliferator activated receptor gamma22500225
Phenylethanolamine N-methyltransferase0303
Phenylethanolamine N-methyltransferase0202
CD44 antigen0011
CD44 antigen0112
Alpha-2B adrenergic receptor025429
Amine oxidase [flavin-containing] A048149
Alpha-2C adrenergic receptor025429
Alpha-2A adrenergic receptor026430
Amine oxidase [flavin-containing] B041142
Nicotinamide N-methyltransferase0404
Chain A, Breast cancer type 1 susceptibility protein7007
Chain A, Putative fructose-1,6-bisphosphate aldolase770077
Chain A, HADH2 protein12500125
Chain B, HADH2 protein12500125
Chain A, 2-oxoglutarate Oxygenase13900139
Chain A, ATP-DEPENDENT DNA HELICASE Q1620062
Chain A, Casein kinase II subunit alpha0101
endonuclease IV460046
15-lipoxygenase, partial800080
cytochrome P450 family 3 subfamily A polypeptide 425500255
G18600186
cytochrome P450 2D616900169
67.9K protein11600116
cellular tumor antigen p53 isoform a810081
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 112300123
thyroid hormone receptor beta isoform a12600126
mitogen-activated protein kinase 111300113
dual specificity mitogen-activated protein kinase kinase 12002
RAF proto-oncogene serine/threonine-protein kinase isoform b2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a410041
nuclear receptor ROR-gamma isoform 116200162
cytochrome P450 3A4 isoform 119000190
Gamma-aminobutyric acid receptor subunit pi190368235
Polyunsaturated fatty acid lipoxygenase ALOX15B796085
Urokinase-type plasminogen activator0707
Tissue-type plasminogen activator0505
Interferon beta29700297
HLA class I histocompatibility antigen, B alpha chain 18600186
Integrin beta-3596166
Plasminogen activator inhibitor 10303
Urokinase-type plasminogen activator0303
Integrin alpha-IIb595165
Gamma-aminobutyric acid receptor subunit beta-1190368235
Gamma-aminobutyric acid receptor subunit delta190368235
Gamma-aminobutyric acid receptor subunit gamma-21903610237
Casein kinase II subunit alpha 0303
Glutamate receptor 1144220
Glutamate receptor 3144220
Glutamate receptor 4144220
Casein kinase II subunit alpha'0165167
Gamma-aminobutyric acid receptor subunit alpha-5190368235
Gamma-aminobutyric acid receptor subunit alpha-3190368235
Gamma-aminobutyric acid receptor subunit gamma-1190368235
Gamma-aminobutyric acid receptor subunit alpha-2190368235
Type-1A angiotensin II receptor 26412
Gamma-aminobutyric acid receptor subunit alpha-4190368235
Gamma-aminobutyric acid receptor subunit gamma-3190368235
Type-1B angiotensin II receptor2709
Gamma-aminobutyric acid receptor subunit alpha-6190368235
Type-2 angiotensin II receptor29011
DNA repair protein RAD52 homolog0505
Histamine H2 receptor12553138
Gamma-aminobutyric acid receptor subunit alpha-11903910240
Gamma-aminobutyric acid receptor subunit beta-3190368235
Gamma-aminobutyric acid receptor subunit beta-21903610237
Casein kinase II subunit beta016016
Casein kinase II subunit beta0303
Casein kinase II subunit alpha0192342
Disintegrin and metalloproteinase domain-containing protein 17307037
Integrase 023226
GABA theta subunit190368235
Inositol hexakisphosphate kinase 118600186
Gamma-aminobutyric acid receptor subunit epsilon190368235
cytochrome P450 2C9, partial18600186
Luciferase17600176
hypoxia-inducible factor 1 alpha subunit11600116
SMAD family member 211900119
SMAD family member 311900119
caspase 7, apoptosis-related cysteine protease880088
estrogen receptor 2 (ER beta)19200192
nuclear receptor subfamily 1, group I, member 325800258
retinoid X nuclear receptor alpha25300253
pregnane X nuclear receptor26500265
vitamin D (1,25- dihydroxyvitamin D3) receptor18900189
caspase-3880088
thyroid stimulating hormone receptor12400124
thyrotropin-releasing hormone receptor310031
v-jun sarcoma virus 17 oncogene homolog (avian)15500155
Histone H2A.x14400144
histone deacetylase 9 isoform 3510051
Papain0101
DNA topoisomerase 1010326
Indoleamine 2,3-dioxygenase 1014116
Carbon monoxide dehydrogenase small chain0022
Dual specificity protein phosphatase 10303
M-phase inducer phosphatase 20707
RAC-alpha serine/threonine-protein kinase0165167
Alpha-synuclein4020161
Dual specificity mitogen-activated protein kinase kinase 10135164
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10516
Genome polyprotein 0404
Dual specificity protein phosphatase 60303
Histone-lysine N-methyltransferase EHMT20909
Histone-lysine N-methyltransferase EHMT10404
Beta-lactamase 0202
ATAD5 protein, partial14700147
apical membrane antigen 1, AMA1500050
chromobox protein homolog 118400184
lethal factor (plasmid)940195
botulinum neurotoxin type A0011
botulinum neurotoxin type F, BoNT/F0011
GLS protein13800138
IDH110800108
Bloom syndrome protein isoform 112300123
cytochrome P450 2C9 precursor760076
ras-related protein Rab-9A610061
lamin isoform A-delta1026800268
Poly [ADP-ribose] polymerase 20303
Poly [ADP-ribose] polymerase 1015623
Protein mono-ADP-ribosyltransferase PARP150707
ATP-dependent phosphofructokinase13400134
Deoxyhypusine synthase0101
phosphopantetheinyl transferase14200142
prostaglandin E2 receptor EP2 subtype3005
histone acetyltransferase KAT2A isoform 111100111
Transient receptor potential cation channel subfamily A member 1021720
Peroxisome proliferator-activated receptor gamma0142239
acetylcholinesterase11700117
pregnane X receptor530053
progesterone receptor20500205
arylsulfatase A930093
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a20600206
activating transcription factor 614300143
nuclear receptor subfamily 1, group I, member 2460046
Glucocorticoid receptor135961
Sex hormone-binding globulin011213
Glycine receptor subunit alpha-1030030
Corticosteroid-binding globulin010010
Adenosine receptor A3050354
Replicase polyprotein 1ab0612182
Androgen receptor048150
Alpha-1B adrenergic receptor074478
Glycine receptor subunit beta030030
Glycine receptor subunit alpha-2030030
Glycine receptor subunit alpha-3030030
Mitogen-activated protein kinase 3 075159
Alpha-1A adrenergic receptor075580
Sodium-dependent dopamine transporter 044145
TAR DNA-binding protein 43781079
PPM1D protein14700147
EWS/FLI fusion protein24700248
Inhibitor of nuclear factor kappa-B kinase subunit beta052228
Tyrosine-protein kinase JAK20123446
Interferon-induced, double-stranded RNA-activated protein kinase042327
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Methyltransferase Wbdd0101
NFKB1 protein, partial500050
Thrombopoietin470047
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)860086
Parkin470047
cytochrome P450 2D6 isoform 1850085
cytochrome P450 2C19 precursor800080
serine/threonine-protein kinase mTOR isoform 1670067
M-phase phosphoprotein 8660066
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0192646
cGMP-dependent 3',5'-cyclic phosphodiesterase0404
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha0202
Serine/threonine-protein kinase PLK4095261
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta022325
Bromodomain-containing protein 4010717
5-hydroxytryptamine receptor 4058260
cGMP-specific 3',5'-cyclic phosphodiesterase012012
Cytochrome P450 1A2058264
Neuronal acetylcholine receptor subunit alpha-41122438
Serine/threonine-protein kinase pim-10125368
Neuronal acetylcholine receptor subunit beta-21120436
Proteinase-activated receptor 10214
Bromodomain-containing protein 20314
Phosphatidylinositol 3-kinase regulatory subunit alpha012114
5-hydroxytryptamine receptor 2A056261
5-hydroxytryptamine receptor 2C064266
Sodium-dependent serotonin transporter023326
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0101
Type-1 angiotensin II receptor0639
5-hydroxytryptamine receptor 2B065267
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0252854
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0192647
Serine/threonine-protein kinase mTOR0212748
Serine/threonine-protein kinase mTOR0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0232650
Glycogen synthase kinase-3 beta0235275
D(1A) dopamine receptor323035
Serine/threonine-protein kinase PLK10234064
DNA-dependent protein kinase catalytic subunit016117
Mu-type opioid receptor022325
Serine-protein kinase ATM0909
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0606
Serine/threonine-protein kinase ATR072128
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0606
Bromodomain-containing protein 30314
Serine/threonine-protein kinase pim-3022426
Phosphoinositide 3-kinase regulatory subunit 50404
Serine/threonine-protein kinase PLK30142438
Serine/threonine-protein kinase PLK20122335
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a12900129
thyroid hormone receptor beta isoform 229100291
Aldo-keto reductase family 1 member B1074074
Alpha-2A adrenergic receptor063872
Sodium-dependent noradrenaline transporter 068876
Sodium-dependent serotonin transporter063467
ATPase family AAA domain-containing protein 513800138
Ataxin-217400174
Retinal dehydrogenase 10314
Signal transducer and activator of transcription 309313
Protein cereblon021329
Pteridine reductase 10505
Chain A, Beta-lactamase940094
glp-1 receptor, partial960096
lysosomal alpha-glucosidase preproprotein360036
interferon gamma precursor00012
nuclear factor erythroid 2-related factor 2 isoform 2900091
atrial natriuretic peptide receptor 2 precursor310031
DNA dC->dU-editing enzyme APOBEC-3G isoform 1227029
Tubulin alpha-1A chain08312
Tubulin beta chain08311
Cytochrome P450 1A1026229
Cytochrome P450 1B1029130
Tubulin beta-2B chain010114
Similar to alpha-tubulin isoform 1 08112
Similar to alpha-tubulin isoform 1 08011
peroxisome proliferator-activated receptor delta19900199
DNA repair and recombination protein RadA0022
Cytochrome P450 2A6011214
Sulfotransferase 1A1 0002
Cytochrome P450 2A50304
Sulfotransferase 1E10001
Sulfotransferase 1A10215
Sulfotransferase 2A10001
ClpP140014
Neutrophil cytosol factor 10404
Nuclear receptor ROR-gamma764484
Alcohol dehydrogenase E chain0303
Alcohol dehydrogenase S chain0303
Peptidyl-prolyl cis-trans isomerase FKBP50213
heat shock protein beta-112200122
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)570057
Glycoprotein hormones alpha chain110011
Cytochrome P450 1A10023
Aryl hydrocarbon receptor0157
G-protein coupled bile acid receptor 1021517
Prostaglandin G/H synthase 1046047
Prostaglandin G/H synthase 20562584
Fumarate hydratase13500135
thioredoxin glutathione reductase500050
Smad310300103
nonstructural protein 1580058
polyprotein13500135
bromodomain adjacent to zinc finger domain 2B650065
NPC intracellular cholesterol transporter 1 precursor520052
peripheral myelin protein 22 isoform 1760076
FAD-linked sulfhydryl oxidase ALR0004
muscarinic acetylcholine receptor M1690069
Guanylate cyclase soluble subunit beta-20012
Guanylate cyclase soluble subunit alpha-20012
Guanylate cyclase soluble subunit alpha-10012
Guanylate cyclase soluble subunit beta-10012
Histone acetyltransferase p3000516
Hypoxia-inducible factor 1-alpha09212
CREB-binding protein2417
Endothelial PAS domain-containing protein 10517
Poly [ADP-ribose] polymerase 1 0101
Transporter015218
Ribonucleoside-diphosphate reductase subunit M20101
CDGSH iron-sulfur domain-containing protein 1014014
Neuraminidase 019019
Calpain-1 catalytic subunit0101
Carbonic anhydrase 12037147
Carbonic anhydrase 10881107
Carbonic anhydrase 20942115
ATP-dependent translocase ABCB106816112
Calmodulin-10617
Androgen receptor123539
Pyruvate kinase PKM09211
Polyunsaturated fatty acid lipoxygenase ALOX15010011
Polyunsaturated fatty acid lipoxygenase ALOX120809
Xanthine dehydrogenase/oxidase025025
Fatty acid synthase012012
Carbonic anhydrase 9048159
Aurora kinase B0245175
Dipeptidyl peptidase 30707
HSP40, subfamily A [Plasmodium falciparum 3D7]0006
Chain A, DNA-3-methyladenine glycosylase I0011
Chain A, DNA-3-METHYLADENINE GLYCOSYLASE I0011
Chain A, Dna-3-methyladenine Glycosylase I0011
Tyrosine-protein kinase Lck0295383
Tyrosine-protein kinase Fyn0295281
Acetylcholinesterase053255
Pancreatic triacylglycerol lipase011012
Carbonic anhydrase 4054162
Carbonic anhydrase 7036144
Oligo-1,6-glucosidase IMA10202
Mitogen-activated protein kinase 100165167
Aldo-keto reductase family 1 member B10202
Inositol polyphosphate multikinase0707
Enoyl-acyl-carrier protein reductase 013013
3-oxoacyl-acyl-carrier protein reductase 0808
Inositol hexakisphosphate kinase 20707
pyruvate kinase PKM isoform a110011
Tubulin--tyrosine ligase0202
Macrophage migration inhibitory factor013114
DNA topoisomerase type IB small subunit0011
DNA topoisomerase I 0011
Aryl hydrocarbon receptor0022
G-protein coupled receptor 840011
G-protein coupled receptor 840012
alpha-galactosidase320032
fructose-bisphosphate aldolase A4004
Chain A, TGF-beta receptor type-10101
tyrosine-protein kinase Yes440044
Serine/threonine-protein kinase 25002323
Citron Rho-interacting kinase015152
Serine/threonine-protein kinase RIO3002323
Serine/threonine-protein kinase Chk1035255
Aurora kinase A0145367
Cyclin-G-associated kinase035356
Serine/threonine-protein kinase DCLK1002323
Muscle, skeletal receptor tyrosine-protein kinase002323
3-phosphoinositide-dependent protein kinase 1072431
Death-associated protein kinase 3002424
Receptor-interacting serine/threonine-protein kinase 2055156
NUAK family SNF1-like kinase 1042327
Ribosomal protein S6 kinase alpha-5015253
Ribosomal protein S6 kinase alpha-4005151
Serine/threonine-protein kinase 16005252
Serine/threonine-protein kinase PAK 3002323
Serine/threonine-protein kinase 17B002323
Serine/threonine-protein kinase 10015152
Serine/threonine-protein kinase D3085261
Cyclin-dependent kinase 14002323
Mitogen-activated protein kinase kinase kinase kinase 4015152
Serine/threonine-protein kinase LATS1005151
Serine/threonine-protein kinase PAK 4025153
Tyrosine-protein kinase ABL10405599
Epidermal growth factor receptor06857125
RAF proto-oncogene serine/threonine-protein kinase0102435
Receptor tyrosine-protein kinase erbB-20342660
High affinity nerve growth factor receptor044852
Insulin receptor0135165
Tyrosine-protein kinase Fes/Fps015152
Macrophage colony-stimulating factor 1 receptor0112334
Tyrosine-protein kinase Yes095160
Tyrosine-protein kinase Lyn095160
Proto-oncogene tyrosine-protein kinase receptor Ret0155166
Insulin-like growth factor 1 receptor0145266
Hepatocyte growth factor receptor0144964
Tyrosine-protein kinase HCK0105161
Proto-oncogene tyrosine-protein kinase ROS052328
Platelet-derived growth factor receptor beta0275179
Tyrosine-protein kinase Fgr033235
Mast/stem cell growth factor receptor Kit0232548
Fibroblast growth factor receptor 10205275
Myosin light chain kinase, smooth muscle011314
Proto-oncogene tyrosine-protein kinase Src0345186
Insulin receptor-related protein002323
Serine/threonine-protein kinase B-raf0125366
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform005252
Platelet-derived growth factor receptor alpha0182442
Tyrosine-protein kinase Fer015152
cAMP-dependent protein kinase catalytic subunit alpha085159
Vascular endothelial growth factor receptor 1 0172340
Cyclin-dependent kinase 11B002323
Ephrin type-A receptor 1004646
Fibroblast growth factor receptor 2062330
Fibroblast growth factor receptor 4062330
Fibroblast growth factor receptor 3062431
cAMP-dependent protein kinase catalytic subunit beta065157
Tyrosine-protein kinase JAK1075158
Protein kinase C eta type092535
Activin receptor type-2A002323
MAP/microtubule affinity-regulating kinase 3015152
Mitogen-activated protein kinase 10115162
Ephrin type-A receptor 20105161
Ephrin type-A receptor 3002424
Ephrin type-A receptor 8002323
Ephrin type-B receptor 2055257
Leukocyte tyrosine kinase receptor002323
Non-receptor tyrosine-protein kinase TYK2055156
Wee1-like protein kinase005151
Tyrosine-protein kinase receptor UFO072330
Mitogen-activated protein kinase 4002323
RAC-beta serine/threonine-protein kinase045155
Dual specificity protein kinase TTK014142
Tyrosine-protein kinase receptor Tie-1002323
Vascular endothelial growth factor receptor 30152338
Vascular endothelial growth factor receptor 20392567
Dual specificity mitogen-activated protein kinase kinase 2075158
Receptor-type tyrosine-protein kinase FLT30305183
Bone morphogenetic protein receptor type-1A015152
Activin receptor type-1B035154
TGF-beta receptor type-1085260
Serine/threonine-protein kinase receptor R3012526
TGF-beta receptor type-2034952
Tyrosine-protein kinase CSK075158
Tyrosine-protein kinase Tec045256
Tyrosine-protein kinase TXK042529
Tyrosine-protein kinase ABL2035154
Tyrosine-protein kinase FRK025153
Tyrosine-protein kinase ZAP-70062329
Tyrosine-protein kinase SYK0145569
Mitogen-activated protein kinase 8045256
Mitogen-activated protein kinase 9045256
Dual specificity mitogen-activated protein kinase kinase 4013536
Dual specificity mitogen-activated protein kinase kinase 3005151
Casein kinase I isoform delta025153
MAP kinase-activated protein kinase 2025153
Cyclin-dependent kinase 8012324
Casein kinase I isoform epsilon025254
Dual specificity protein kinase CLK1024850
Dual specificity protein kinase CLK2014647
Dual specificity protein kinase CLK3003838
Glycogen synthase kinase-3 alpha095160
Cyclin-dependent kinase 7075158
Cyclin-dependent kinase 9085159
Tyrosine-protein kinase Blk052530
Ribosomal protein S6 kinase alpha-3035255
Cytoplasmic tyrosine-protein kinase BMX072532
cAMP-dependent protein kinase catalytic subunit PRKX002424
Serine/threonine-protein kinase Nek2025153
Tyrosine-protein kinase JAK30162541
Dual specificity mitogen-activated protein kinase kinase 6015152
Death-associated protein kinase 10102333
LIM domain kinase 1015152
LIM domain kinase 2015152
5'-AMP-activated protein kinase catalytic subunit alpha-2022326
Ephrin type-B receptor 3005151
Ephrin type-A receptor 5005151
Ephrin type-B receptor 40105161
Ephrin type-B receptor 1002323
Ephrin type-A receptor 4015152
Serine/threonine-protein kinase SIK1022325
Tubulin alpha-1A chain001313
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta002323
SRSF protein kinase 2002323
Casein kinase I isoform gamma-2004343
Mitogen-activated protein kinase kinase kinase 9022325
Cyclin-dependent kinase 3005050
Cyclin-dependent-like kinase 5 095160
Cyclin-dependent kinase 16005252
Cyclin-dependent kinase 17004848
Protein kinase C epsilon type0122538
Angiopoietin-1 receptor0112536
Mitogen-activated protein kinase kinase kinase 10002323
Protein kinase C theta type0105162
Activin receptor type-1025153
Focal adhesion kinase 1095160
Protein kinase C delta type0115365
Tyrosine-protein kinase BTK0115465
Tyrosine-protein kinase receptor TYRO3012324
Cyclin-dependent kinase 18002828
Activated CDC42 kinase 1025153
Epithelial discoidin domain-containing receptor 1055156
Tyrosine-protein kinase ITK/TSK062531
Myotonin-protein kinase012324
Tyrosine-protein kinase Mer043135
Serine/threonine-protein kinase 4015253
5'-AMP-activated protein kinase catalytic subunit alpha-1025154
Serine/threonine-protein kinase PAK 1032326
Mitogen-activated protein kinase 7005050
Serine/threonine-protein kinase PAK 2014748
Serine/threonine-protein kinase 3015152
cGMP-dependent protein kinase 2002323
Non-receptor tyrosine-protein kinase TNK1005151
Receptor-interacting serine/threonine-protein kinase 1042327
Calcium/calmodulin-dependent protein kinase type II subunit beta012324
Calcium/calmodulin-dependent protein kinase type II subunit gamma015152
Calcium/calmodulin-dependent protein kinase type II subunit delta005151
Activin receptor type-2B005050
Bone morphogenetic protein receptor type-2015152
Protein-tyrosine kinase 6025153
cGMP-dependent protein kinase 1 005252
Calcium/calmodulin-dependent protein kinase type 1002424
Inhibitor of nuclear factor kappa-B kinase subunit epsilon005151
Protein-tyrosine kinase 2-beta025153
Maternal embryonic leucine zipper kinase035154
Serine/threonine-protein kinase D1082433
Ribosomal protein S6 kinase alpha-2012425
Ephrin type-A receptor 7004747
Ribosomal protein S6 kinase alpha-1065157
Dual specificity testis-specific protein kinase 1004747
Myosin light chain kinase, smooth muscle035154
Serine/threonine-protein kinase STK11015152
NT-3 growth factor receptor012324
Serine/threonine-protein kinase N1015152
Serine/threonine-protein kinase N2025153
Calcium/calmodulin-dependent protein kinase type IV005050
Mitogen-activated protein kinase kinase kinase 11005151
BDNF/NT-3 growth factors receptor032326
Mitogen-activated protein kinase 6002323
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform002323
Discoidin domain-containing receptor 2085159
AP2-associated protein kinase 1015253
Serine/threonine-protein kinase TNNI3K012324
Serine/threonine-protein kinase MRCK alpha005151
Serine/threonine-protein kinase MRCK gamma004949
Serine/threonine-protein kinase Nek5002323
Serine/threonine-protein kinase MARK2005252
Serine/threonine-protein kinase tousled-like 2002323
Serine/threonine-protein kinase 32C002323
Myosin light chain kinase family member 4002323
Calcium/calmodulin-dependent protein kinase type 1D012425
Mitogen-activated protein kinase kinase kinase kinase 3015152
MAP kinase-activated protein kinase 5034851
Serine/threonine-protein kinase BRSK2002323
Serine/threonine-protein kinase DCLK2002323
Calcium/calmodulin-dependent protein kinase kinase 1002323
Casein kinase I isoform alpha-like002323
Myosin-IIIa002323
Ankyrin repeat and protein kinase domain-containing protein 1002323
Atypical kinase COQ8A, mitochondrial005151
Mitogen-activated protein kinase 15005151
Serine/threonine-protein kinase Nek9005151
Serine/threonine-protein kinase BRSK1002323
Serine/threonine-protein kinase Nek7004141
Myosin-IIIb002323
Mitogen-activated protein kinase kinase kinase kinase 1005050
Atypical kinase COQ8B, mitochondrial002323
MAP/microtubule affinity-regulating kinase 4004848
Calcium/calmodulin-dependent protein kinase type 1G002929
Serine/threonine-protein kinase Nek1005151
Calcium/calmodulin-dependent protein kinase kinase 2005252
SRSF protein kinase 1002323
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase065157
Mitogen-activated protein kinase kinase kinase 5015152
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha002323
Serine/threonine-protein kinase RIO1002323
MAP kinase-interacting serine/threonine-protein kinase 1032326
Cyclin-dependent kinase 19012324
Testis-specific serine/threonine-protein kinase 1002323
Serine/threonine-protein kinase 33002323
Serine/threonine-protein kinase D2005151
Serine/threonine-protein kinase DCLK3002323
NUAK family SNF1-like kinase 2004949
Serine/threonine-protein kinase SIK2015152
Myosin light chain kinase 2, skeletal/cardiac muscle002323
STE20-like serine/threonine-protein kinase 005252
Tyrosine-protein kinase Srms002323
Dual specificity protein kinase CLK4004141
MAP kinase-interacting serine/threonine-protein kinase 2032427
Serine/threonine-protein kinase Nek6012324
Casein kinase I isoform gamma-1005252
Serine/threonine-protein kinase PAK 6013940
Serine/threonine-protein kinase LATS2002323
Serine/threonine-protein kinase 36012324
BMP-2-inducible protein kinase005252
Serine/threonine-protein kinase 32B002323
Mitogen-activated protein kinase kinase kinase 20015152
Serine/threonine-protein kinase MARK1012324
Serine/threonine-protein kinase pim-2004040
Serine/threonine-protein kinase PAK 5012324
Serine/threonine-protein kinase 26005151
eIF-2-alpha kinase GCN2012324
Serine/threonine-protein kinase NLK015051
Serine/threonine-protein kinase 17A002424
Ephrin type-A receptor 6002323
Death-associated protein kinase 2002424
Ribosomal protein S6 kinase alpha-6015152
TRAF2 and NCK-interacting protein kinase015253
Serine/threonine-protein kinase tousled-like 1002323
ALK tyrosine kinase receptor0142842
Cyclin-dependent kinase 11A002323
Aurora kinase C032427
Calcium/calmodulin-dependent protein kinase type II subunit alpha002323
RAC-gamma serine/threonine-protein kinase035053
Serine/threonine-protein kinase 38-like003535
Dual specificity tyrosine-phosphorylation-regulated kinase 1B023436
Mitogen-activated protein kinase kinase kinase kinase 5015152
Serine/threonine-protein kinase MRCK beta005151
Interleukin-1 receptor-associated kinase 3005151
Serine/threonine-protein kinase 24014445
Casein kinase I isoform gamma-3005151
Mitogen-activated protein kinase kinase kinase 4005151
transcriptional regulator ERG isoform 3230023
peripheral myelin protein 2215200152
Potassium channel subfamily K member 20358
Rap guanine nucleotide exchange factor 3410041
Potassium voltage-gated channel subfamily A member 30213
Acetylcholinesterase0405
Potassium voltage-gated channel subfamily A member 10415
Potassium voltage-gated channel subfamily H member 2098099
NPYLR7B001212
Replicase polyprotein 1ab0191635
Transient receptor potential cation channel subfamily A member 10448
5-hydroxytryptamine receptor 2C021123
5-hydroxytryptamine receptor 2A032235
5-hydroxytryptamine receptor 1A053764
5-hydroxytryptamine receptor 1B028129
5-hydroxytryptamine receptor 1D012113
5-hydroxytryptamine receptor 1F012113
5-hydroxytryptamine receptor 2B020222
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 7 0819
5-hydroxytryptamine receptor 5A0213
5-hydroxytryptamine receptor 5B0213
5-hydroxytryptamine receptor 3A012214
5-hydroxytryptamine receptor 4 0327
5-hydroxytryptamine receptor 3B012214
Fatty acid synthase0606
Fatty acid synthase 0101
interleukin 8600060
nuclear factor NF-kappa-B p105 subunit isoform 1200222
1-deoxy-D-xylulose-5-phosphate synthase0101
Chain A, TRYPSIN0101
Chain A, TRYPSIN0101
Chain A, TRYPSIN0101
Chain A, TRYPSIN0101
Chain A, TRYPSIN0101
Chain A, TRYPSIN0101
Membrane primary amine oxidase0001
Cationic trypsin0707
Membrane primary amine oxidase0001
Rapamycin-insensitive companion of mTOR0303
Regulatory-associated protein of mTOR0505
Phosphatidylinositol 3-kinase catalytic subunit type 30325
Target of rapamycin complex 2 subunit MAPKAP10303
Target of rapamycin complex subunit LST80606
Lysine-specific demethylase 4E011011
lethal(3)malignant brain tumor-like protein 1 isoform I200020
Lysine-specific demethylase 6B0303
Lysine-specific demethylase 6A0202
Lysine-specific demethylase 4A0325
Lysine-specific demethylase 4B0202
Lysine-specific demethylase 5C0101
Lysine-specific demethylase 4D0101
Methylcytosine dioxygenase TET20314
Prolyl 4-hydroxylase0606
Alpha-ketoglutarate-dependent dioxygenase FTO0606
Egl nine homolog 103610
Lysine-specific demethylase 4C0202
Lysine-specific demethylase 2A0101
Lysine-specific demethylase 3A0101
Polyunsaturated fatty acid 5-lipoxygenase033135
dopamine D1 receptor180018
5-hydroxytryptamine receptor 1A018523
5-hydroxytryptamine receptor 1D0408
5-hydroxytryptamine receptor 1B0516
Cholecystokinin receptor type A08311
Gastrin/cholecystokinin type B receptor07310
5-hydroxytryptamine receptor 7017118
5-hydroxytryptamine receptor 6033137
Fatty-acid amide hydrolase 1211013
5-hydroxytryptamine receptor 40527
Transient receptor potential cation channel subfamily M member 80236
parathyroid hormone/parathyroid hormone-related peptide receptor precursor520052
muscleblind-like protein 1 isoform 1560056
Monocarboxylate transporter 40103
Pannexin-10101
Trypsin-10707
Trypsin-20606
Cyclic AMP-responsive element-binding protein 10002
Trypsin-30606
BRCA1180018
nuclear receptor subfamily 0 group B member 10808
steroidogenic factor 10808
Urease subunit alpha012012
Urease subunit beta012012
Broad substrate specificity ATP-binding cassette transporter ABCG2056665
Solute carrier organic anion transporter family member 2A10309
Tyrosinase0808
Neutrophil elastase016017
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0707
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0608
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0606
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0808
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Olfactory receptor 51E20167
Trypsin0708
Coagulation factor VII010010
Tissue factor014014
Oxoeicosanoid receptor 10202
PAX800011
Hsf1 protein0056
photoreceptor-specific nuclear receptor0303
DNA polymerase beta540054
transactivating tegument protein VP16 [Human herpesvirus 1]0808
P53110011
Caspase-7360036
serine-protein kinase ATM isoform a160016
caspase-3360036
caspase-1 isoform alpha precursor200020
Caspase-7180019
Chain A, Heat shock protein HSP 90-alpha0101
Chain A, Heat shock protein HSP 90-alpha0101
Heat shock protein HSP 90-alpha0141428
Heat shock protein HSP 90-beta011822
Endoplasmin0538
Endoplasmin0415
Heat shock protein 75 kDa, mitochondrial0506
Nrf2160016
hexokinase-4 isoform 1110011
potassium voltage-gated channel subfamily H member 2 isoform d10100101
glucokinase regulatory protein110011
neuropeptide S receptor isoform A550055
Nuclear receptor subfamily 1 group I member 2021820
Polyunsaturated fatty acid 5-lipoxygenase010015
Polyunsaturated fatty acid 5-lipoxygenase0303
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
M17 leucyl aminopeptidase0202
Albumin0142041
Replicase polyprotein 1ab0391958
Reverse transcriptase/RNaseH 017838
Spike glycoprotein146715168
RNA-directed RNA polymerase 0225
ATP-binding cassette sub-family C member 301850185
Multidrug resistance-associated protein 401890196
Solute carrier family 22 member 6023027
UDP-glucuronosyltransferase 1A902012
Bile salt export pump040042
Bile salt export pump02700272
Cytochrome P450 2B10304
Myoglobin0101
Prostaglandin G/H synthase 1033337
Carbonic anhydrase 3022130
Cytochrome P450 2D6059363
Polyunsaturated fatty acid lipoxygenase ALOX15025025
UDP-glucuronosyltransferase 1-609012
Arachidonate 5-lipoxygenase-activating protein0303
UDP-glucuronosyltransferase 1A1 017023
Carbonic anhydrase 6031139
Carbonic anhydrase 5A, mitochondrial036146
Cytochrome P450 2J2033034
Canalicular multispecific organic anion transporter 101780179
Carbonic anhydrase 15023029
Carbonic anhydrase 13020026
Carbonic anhydrase 14025134
Carbonic anhydrase 5B, mitochondrial028138
toxin B0001
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0003
Carbonic anhydrase 0909
GALC protein320032
Carbonic anhydrase 0404
Carbonic anhydrase 0808
Carbonic anhydrase0808
Carbonic anhydrase0101
Prolyl endopeptidase0202
Carbonic anhydrase-related protein 110102
Glycogen phosphorylase, muscle form0909
Renin0617
Carbonic anhydrase 20202
Cathepsin B0101
Steryl-sulfatase0304
Cytochrome P450 2C8016018
Translocator protein014419
Cytochrome P450 2B6015118
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A1222232
Serum paraoxonase/arylesterase 10808
Dipeptidyl peptidase 4016017
Endochitinase0101
Adenosine receptor A2a020331
Delta-type opioid receptor020327
Cytochrome P450 2C19043147
Delta-type opioid receptor019122
Mu-type opioid receptor026433
Carbonic anhydrase022027
Kappa-type opioid receptor018225
Carbonic anhydrase0202
Corticosteroid 11-beta-dehydrogenase isozyme 10314
Carbonic anhydrase04010
D(2) dopamine receptor030234
Cholinesterase017018
Carbonic anhydrase 0303
Beta-carbonic anhydrase 10606
Carbonic anhydrase 20505
Glutamate receptor ionotropic, NMDA 2B024638
Squalene synthase0506
Neuronal acetylcholine receptor subunit alpha-7010516
Carbonic anhydrase0606
Carbonic anhydrase, alpha family 0606
Carbonic anhydrase 0309
Carbonic anhydrase 30808
Carbonic anhydrase07014
Carbonic anhydrase04011
Carbonic anhydrase 0404
Sigma intracellular receptor 2010010
Delta carbonic anhydrase0404
Sigma non-opioid intracellular receptor 1018321
Renin0101
Carbonic anhydrase 0309
Endochitinase A10101
Multidrug resistance-associated protein 10202
Carbonic anhydrase 13010115
Carbonic anhydrase 408012
Acidic mammalian chitinase0101
Carbonic anhydrase 70101
Carbonic anhydrase 0606
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Free fatty acid receptor 30033
Free fatty acid receptor 20224
Fibrinogen C domain-containing protein 10202
D(1A) dopamine receptor510051
Histone deacetylase 3034342
Histone deacetylase 4030339
Histone deacetylase 1040752
Histone deacetylase 7029337
Histone deacetylase 2038649
Polyamine deacetylase HDAC10027234
Histone deacetylase 11 028235
Histone deacetylase 8034544
Histone deacetylase 6036648
Histone deacetylase 9028235
Histone deacetylase 5030237
Putative glycosyltransferase WbgO0001
Killer cell lectin-like receptor subfamily B member 1A0101
Early activation antigen CD690101
eyes absent homolog 2 isoform a140014
Rap guanine nucleotide exchange factor 4270027
Synaptic vesicular amine transporter0404
Receptor tyrosine-protein kinase erbB-4082432
Platelet glycoprotein VI0359
Telomerase reverse transcriptase0707
Amyloid-beta precursor protein1031346
DNA topoisomerase 2-alpha0104466
integrase, partial0505
lens epithelium-derived growth factor p750505
hypothetical protein, conserved230023
Arginase 0707
Protein kinase C alpha type0606
Protein kinase C delta type0606
Protein kinase C epsilon type0606
Protein kinase C zeta type0606
Protein kinase C alpha type0195173
Protein kinase C gamma type0606
Protein kinase C beta type0606
Prostaglandin G/H synthase 2022023
Protein kinase C eta type0606
Protein kinase C theta type0606
Histone deacetylase 60101
Leukotriene A-4 hydrolase012114
Proteasome subunit beta type-5024026
NAD-dependent protein deacetylase sirtuin-2010111
NAD-dependent protein deacetylase sirtuin-109112
Nuclear receptor corepressor 2011011
Chain E, Purine nucleoside phosphorylase0101
Thymidine kinase 0708
hemoglobin subunit beta130013
atrial natriuretic peptide receptor 1 precursor240024
Solute carrier family 22 member 1 045057
Purine nucleoside phosphorylase0507
Thymidine kinase, cytosolic09015
POU domain, class 2, transcription factor 20002
Purine nucleoside phosphorylase0033
Solute carrier family 22 member 6017027
Thymidine kinase 0101
Solute carrier family 22 member 8014023
Thymidine kinase0304
60 kDa chaperonin020020
Retinoic acid receptor alpha07819
60 kDa heat shock protein, mitochondrial024024
Retinoic acid receptor beta07819
Retinoic acid receptor gamma 08820
Aspartate aminotransferase, cytoplasmic0101
Glycine receptor subunit alpha-10077
10 kDa heat shock protein, mitochondrial024024
Thiosulfate sulfurtransferase023023
60 kDa chaperonin 024024
10 kDa chaperonin 024024
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
tumor susceptibility gene 101 protein9009
Cyclin-dependent kinase 10234872
Leucine-rich repeat serine/threonine-protein kinase 2032225
Chain A, Membrane lipoprotein tmpC0033
Chain A, Membrane lipoprotein tmpC0033
Chain A, Membrane lipoprotein tmpC0033
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
signal transducer and activator of transcription 6, interleukin-4 induced3003
glycogen synthase kinase-3 beta isoform 1001010
high affinity choline transporter 1 isoform a0404
Sodium/nucleoside cotransporter 10505
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 7002323
Sodium/nucleoside cotransporter 20606
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0404
Phosphoglycerate kinase 20101
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Inosine-5'-monophosphate dehydrogenase 2034346
Inosine-5'-monophosphate dehydrogenase 1 0303
Streptavidin0022
Adenosylhomocysteinase0205
Adenosine receptor A30505
Adenosine receptor A2a025736
Adenosine receptor A2b0217
Adenosine receptor A2b0428
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A1023433
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0405
Adenosine receptor A10314
Adenosine kinase004647
Adenosine deaminase 0102
Equilibrative nucleoside transporter 20404
Phosphatidylinositol 4-kinase type 2-beta0304
Histone-lysine N-methyltransferase, H3 lysine-79 specific0314
Equilibrative nucleoside transporter 1010010
Phosphatidylinositol 4-kinase type 2-alpha0405
Solute carrier family 28 member 30505
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta062330
5-methylthioadenosine/S-adenosylhomocysteine deaminase0002
Adenosine transporter 10001
Transient receptor potential cation channel subfamily M member 20011
Acetylcholinesterase0606
Bone morphogenetic protein receptor type-1B015051
Membrane-associated progesterone receptor component 1003636
Cell division cycle 7-related protein kinase003333
ATP-dependent RNA helicase DDX3X004848
Pyridoxal kinase004849
Ephrin type-B receptor 6004949
Peroxisomal acyl-coenzyme A oxidase 3004848
Mitotic checkpoint serine/threonine-protein kinase BUB1004545
Dynamin-like 120 kDa protein, mitochondrial004848
Eukaryotic translation initiation factor 5B003232
Rho-associated protein kinase 2035053
Serine/threonine-protein kinase/endoribonuclease IRE1035053
U5 small nuclear ribonucleoprotein 200 kDa helicase004848
Structural maintenance of chromosomes protein 2004848
Mitogen-activated protein kinase kinase kinase 6005050
Guanine nucleotide-binding protein G(i) subunit alpha-2003939
ADP/ATP translocase 2004848
Protein kinase C beta type0135064
Glycogen phosphorylase, liver form024850
Cytochrome c1, heme protein, mitochondrial004646
Serine/threonine-protein kinase A-Raf024749
Glycogen phosphorylase, brain form004848
Breakpoint cluster region protein0135168
Cyclin-dependent kinase 40155066
ADP/ATP translocase 3004848
cAMP-dependent protein kinase type II-alpha regulatory subunit004646
Ribosyldihydronicotinamide dehydrogenase [quinone]0105060
General transcription and DNA repair factor IIH helicase subunit XPD004848
Ras-related protein Rab-6A004545
Multifunctional protein ADE2004848
Ferrochelatase, mitochondrial005050
Ribosomal protein S6 kinase beta-1014950
Beta-adrenergic receptor kinase 1015051
Deoxycytidine kinase004852
Phosphatidylethanolamine-binding protein 1003939
Heme oxygenase 2004747
S-adenosylmethionine synthase isoform type-2004646
DnaJ homolog subfamily A member 1004848
DNA replication licensing factor MCM4004848
Electron transfer flavoprotein subunit beta003838
Glycine--tRNA ligase004848
Protein kinase C iota type075159
Exosome RNA helicase MTR4004848
26S proteasome regulatory subunit 6B024850
Casein kinase I isoform alpha054954
Elongation factor Tu, mitochondrial004848
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial004848
Interleukin-1 receptor-associated kinase 1005050
Serine/threonine-protein kinase Nek3005050
Tyrosine--tRNA ligase, cytoplasmic004747
5'-AMP-activated protein kinase subunit gamma-1014850
Adenylate kinase 2, mitochondrial004748
Ras-related protein Rab-10004646
Actin-related protein 3004848
Actin-related protein 2004747
GTP-binding nuclear protein Ran004848
Cyclin-dependent kinase 60104757
ATP-dependent 6-phosphofructokinase, platelet type004646
DNA topoisomerase 2-beta034961
Macrophage-stimulating protein receptor045054
Mitogen-activated protein kinase kinase kinase kinase 2015051
Dual specificity mitogen-activated protein kinase kinase 5005050
Mitogen-activated protein kinase kinase kinase 1005050
Integrin-linked protein kinase004545
Rho-associated protein kinase 1045054
Dual specificity tyrosine-phosphorylation-regulated kinase 1A055055
Cyclin-dependent kinase 13004949
Structural maintenance of chromosomes protein 1A004444
Chromodomain-helicase-DNA-binding protein 4004545
Peroxisomal acyl-coenzyme A oxidase 1003939
Delta(24)-sterol reductase004848
Myosin light chain kinase 3004949
Putative heat shock protein HSP 90-beta 2004747
Rab-like protein 3004242
Serine/threonine-protein kinase ULK3005050
Uncharacterized protein FLJ45252004848
Serine/threonine-protein kinase/endoribonuclease IRE2004747
ATP-dependent RNA helicase DHX30003535
Serine/threonine-protein kinase TAO1005050
STE20-related kinase adapter protein alpha004848
Myosin-14004747
AarF domain-containing protein kinase 1004848
ATP-dependent RNA helicase DDX42003838
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma004949
ATP-dependent RNA helicase DDX1004848
EKC/KEOPS complex subunit TP53RK004848
Mitogen-activated protein kinase kinase kinase 3005050
Eukaryotic translation initiation factor 2-alpha kinase 1015051
Nucleolar GTP-binding protein 1004646
RNA cytidine acetyltransferase004848
Serine/threonine-protein kinase TAO3005050
dCTP pyrophosphatase 1024850
Phenylalanine--tRNA ligase beta subunit004848
Midasin004848
Interleukin-1 receptor-associated kinase 4015051
Cyclin-dependent kinase 12014849
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13014647
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial004242
5'-AMP-activated protein kinase subunit gamma-2014850
Serine/threonine-protein kinase TBK1045054
Septin-9004848
Serine/threonine-protein kinase TAO2005050
Serine/threonine-protein kinase SIK3015051
Mitogen-activated protein kinase kinase kinase 2005050
Receptor-interacting serine/threonine-protein kinase 3014849
WRN160016
chaperonin-containing TCP-1 beta subunit homolog7007
polyunsaturated fatty acid lipoxygenase ALOX12220022
histone-lysine N-methyltransferase 2A isoform 2 precursor380038
pyruvate kinase PKM isoform b110011
Ornithine decarboxylase112014
Glutamate receptor ionotropic, NMDA 1 023737
Glutamate receptor ionotropic, NMDA 2A 021533
Glutamate receptor ionotropic, NMDA 2C023536
Tyrosyl-DNA phosphodiesterase 10404
large T antigen010111
Glutathione reductase, mitochondrial015020
Transcriptional activator protein LasR0101
Trypanothione reductase08013
Regulatory protein RhlR0101
Alanine racemase, biosynthetic0001
Proton-coupled amino acid transporter 1015016
Adenosine deaminase0001
Transcriptional activator Myb0303
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0202
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0202
Vif0506
Methionine aminopeptidase0202
Chain A, farnesyl pyrophosphate synthase0101
Geranylgeranyl pyrophosphate synthase0608
Farnesyl pyrophosphate synthase0808
Hypoxanthine-guanine phosphoribosyltransferase0202
Farnesyl pyrophosphate synthase 0606
Farnesyl pyrophosphate synthase 0303
Alpha-1A adrenergic receptor0101
Potassium voltage-gated channel subfamily E member 10808
Alpha-1A adrenergic receptor0437
Alpha-1D adrenergic receptor037441
Alpha-1D adrenergic receptor044348
Alpha-1A adrenergic receptor014520
Alpha-1B adrenergic receptor011416
Potassium voltage-gated channel subfamily KQT member 10808
Voltage-dependent L-type calcium channel subunit alpha-1C033034
Sodium channel protein type 5 subunit alpha025025
Potassium voltage-gated channel subfamily D member 30606
retinoic acid receptor alpha isoform 10202
retinoic acid receptor RXR-alpha isoform a0202
Retinoic acid receptor alpha0336
Retinoic acid receptor gamma0235
Retinoic acid receptor RXR-alpha0101226
Retinoic acid receptor beta0235
Nuclear receptor subfamily 4 group A member 10022
Cellular retinoic acid-binding protein 20033
Retinoic acid receptor RXR-alpha0369
Retinoic acid receptor RXR-beta06511
Retinoic acid receptor RXR-beta0268
Retinoic acid receptor RXR-gamma0268
Cellular retinoic acid-binding protein 10304
Retinoic acid receptor RXR-gamma06511
Type-2 angiotensin II receptor0628
Oxysterols receptor LXR-beta0247
Cellular retinoic acid-binding protein 10033
Retinoic acid receptor RXR-alpha0022
Oxysterols receptor LXR-alpha0247
Polyphenol oxidase 2024029
Hypoxanthine-guanine phosphoribosyltransferase0205
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase016120
Shiga toxin subunit A0202
Histamine H3 receptor05113
Thymidylate kinase0606
Botulinum neurotoxin type A 0606
Nitric oxide synthase, endothelial0303
Nitric oxide synthase, brain0506
Nitric oxide synthase, brain 0304
Nitric oxide synthase, inducible0418
Tyrosine-protein kinase 0011
3-hydroxy-3-methylglutaryl-coenzyme A reductase0909
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
phospholipase A2 precursor0202
cysteine protease ATG4B isoform a0202
DNA dC->dU-editing enzyme APOBEC-3F isoform a140014
Free fatty acid receptor 10055
Prostaglandin G/H synthase 1 015018
Aromatase037041
Free fatty acid receptor 40022
Tyrosine-protein phosphatase non-receptor type 1035341
Thromboxane-A synthase 016016
Prostaglandin E2 receptor EP3 subtype0303
Prostaglandin E2 receptor EP4 subtype0314
Prostaglandin E2 receptor EP1 subtype0303
Prostacyclin receptor0426
Nuclear receptor subfamily 4 group A member 20189
Nuclear receptor subfamily 4 group A member 20011
Nuclear receptor subfamily 4 group A member 20011
Prostaglandin E2 receptor EP2 subtype0314
Solute carrier organic anion transporter family member 2A10409
Solute carrier organic anion transporter family member 2B10204
Solute carrier organic anion transporter family member 3A10001
Chain A, Protein (glycogen Phosphorylase)0101
Leukotriene C4 synthase002222
Glycogen synthase kinase-3 beta 0202
[Tau protein] kinase 0202
Dual specificity mitogen-activated protein kinase kinase 7002323
Peripheral plasma membrane protein CASK002222
Inhibitor of nuclear factor kappa-B kinase subunit alpha032225
Mitogen-activated protein kinase kinase kinase 13002222
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma002222
Cyclin-T10707
Serine/threonine-protein kinase ULK1004848
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma002222
Cyclin-K0202
Cyclin-dependent kinase-like 5003535
G2/mitotic-specific cyclin-B20708
Serine/threonine-protein kinase OSR1002222
Serine/threonine-protein kinase Chk2022224
G1/S-specific cyclin-E20202
Vitamin K-dependent protein C0303
Protein kinase C gamma type010213
Adenine phosphoribosyltransferase003333
Signal recognition particle receptor subunit alpha004343
Wee1-like protein kinase 2002222
Uncharacterized serine/threonine-protein kinase SBK3002222
G2/mitotic-specific cyclin-B1017018
G2/mitotic-specific cyclin-B0505
Glycogen synthase kinase-3 beta0606
Serine/threonine-protein kinase MAK002222
Receptor tyrosine-protein kinase erbB-3042226
Nucleoside diphosphate kinase B0077
Dual specificity protein kinase CLK10202
cAMP-dependent protein kinase catalytic subunit gamma063945
G1/S-specific cyclin-D1011012
G1/S-specific cyclin-E10606
Probable ATP-dependent RNA helicase DDX6004646
UMP-CMP kinase 003232
G1/S-specific cyclin-D20304
G1/S-specific cyclin-D30506
G protein-coupled receptor kinase 4002222
Myosin-10003535
Megakaryocyte-associated tyrosine-protein kinase002222
Choline-phosphate cytidylyltransferase A002525
Cysteine--tRNA ligase, cytoplasmic003838
Ras-related protein Rab-27A004646
Cyclin-H0606
CDK-activating kinase assembly factor MAT10404
Serine/threonine-protein kinase Nek4002222
Hormonally up-regulated neu tumor-associated kinase002222
Receptor-interacting serine/threonine-protein kinase 4002222
Cell division control protein 2 homolog002222
Calcium-dependent protein kinase 1002222
Cyclin-A1010011
Serine/threonine-protein kinase PknB002222
Cyclin-dependent kinase-like 1002222
Cyclin homolog0505
Protein kinase C zeta type092939
Mitogen-activated protein kinase kinase kinase 12002222
Serine/threonine-protein kinase PRP4 homolog002222
Cyclin-dependent kinase 5 activator 10909
Cyclin-dependent kinase 10001919
Serine/threonine-protein kinase 38003030
Rhodopsin kinase GRK1012223
La-related protein 70101
Serine/threonine-protein kinase SBK1002222
Mitogen-activated protein kinase kinase kinase 19002222
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0303
Acyl-CoA dehydrogenase family member 10004242
Serine/threonine-protein kinase N3003131
Dual serine/threonine and tyrosine protein kinase002222
Mitogen-activated protein kinase kinase kinase 15002222
Acyl-CoA dehydrogenase family member 11004444
Serine/threonine-protein kinase VRK2002222
Homeodomain-interacting protein kinase 1022224
Cyclin-dependent kinase-like 3012223
Serine/threonine-protein kinase NIM1002222
Serine/threonine-protein kinase ULK2002222
Misshapen-like kinase 1013637
Homeodomain-interacting protein kinase 4022224
Serine/threonine-protein kinase Nek11002222
Serine/threonine-protein kinase 35002222
Rhodopsin kinase GRK7002222
Serine/threonine-protein kinase 32A002222
G2/mitotic-specific cyclin-B30708
Dual specificity tyrosine-phosphorylation-regulated kinase 2022224
Cyclin-dependent kinase-like 2002222
Serine/threonine-protein kinase Sgk3002222
Cyclin-dependent kinase 15002222
PAS domain-containing serine/threonine-protein kinase003535
Dual specificity testis-specific protein kinase 2002727
Serine/threonine-protein kinase RIO2002222
Transient receptor potential cation channel subfamily M member 6002222
Cyclin-dependent kinase 10505
Homeodomain-interacting protein kinase 2022224
Homeodomain-interacting protein kinase 3022224
SNF-related serine/threonine-protein kinase002222
Isoleucine--tRNA ligase, mitochondrial003131
Obg-like ATPase 1004141
STE20/SPS1-related proline-alanine-rich protein kinase002222
Long-chain-fatty-acid--CoA ligase 5003939
SRSF protein kinase 3002222
Serine/threonine-protein kinase ICK004747
Microtubule-associated serine/threonine-protein kinase 1002222
Thyroid hormone receptor-associated protein 3003535
Mcl-10808
Valosin-containing protein0202
Spike glycoprotein071522
Vpr220022
streptokinase A precursor001818
hypothetical protein SA14220202
Gamma-aminobutyric acid receptor subunit pi016016
Gamma-aminobutyric acid receptor subunit delta016016
Transmembrane protease serine 2071522
Group 10 secretory phospholipase A20101
Phospholipase A20101
Estrogen receptor02710
Procathepsin L0111526
72 kDa type IV collagenase020022
Stromelysin-1012214
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-10101
Replicase polyprotein 1a0121527
Replicase polyprotein 1ab091524
Phospholipase A2, membrane associated0304
Matrix metalloproteinase-9017118
Gamma-aminobutyric acid receptor subunit alpha-10221234
Vascular endothelial growth factor A0011
Gamma-aminobutyric acid receptor subunit beta-1017320
Gamma-aminobutyric acid receptor subunit gamma-20211031
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-10101
Gamma-aminobutyric acid receptor subunit beta-3020525
Gamma-aminobutyric acid receptor subunit alpha-5019827
Gamma-aminobutyric acid receptor subunit alpha-3019625
Mu-type opioid receptor0421259
D(3) dopamine receptor058164
Delta-type opioid receptor031743
Kappa-type opioid receptor038649
Cytosolic phospholipase A20202
Gamma-aminobutyric acid receptor subunit alpha-2019524
Gamma-aminobutyric acid receptor subunit beta-2019928
Cannabinoid receptor 20314
Gamma-aminobutyric acid receptor subunit alpha-4017219
Placenta growth factor0011
Beta-secretase 1021022
Gamma-aminobutyric acid receptor subunit epsilon016016
Delta-type opioid receptor0101
5-hydroxytryptamine receptor 1D0101
Gamma-aminobutyric acid receptor subunit alpha-6018220
Estrogen receptor beta0179
Gamma-aminobutyric acid receptor subunit gamma-1016016
Gamma-aminobutyric acid receptor subunit gamma-3016016
Angiotensin-converting enzyme 2 0101626
Poly [ADP-ribose] polymerase 206614
Gamma-aminobutyric acid receptor subunit theta016016
M1-family alanyl aminopeptidase0303
Aminoglycoside 3'-phosphotransferase 0002
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Chain A, Apolipoprotein0011
Plasminogen0718
Gamma-aminobutyric acid receptor subunit rho-10123
Glutamate receptor 10314
Glutamate receptor 20314
Glutamate receptor 30213
Glutamate receptor ionotropic, kainate 31405
Solute carrier family 15 member 1016016
Glutamate receptor 40314
Solute carrier family 15 member 10404
Solute carrier family 15 member 2010010
Nicotinate phosphoribosyltransferase0808
ORF730033
microphthalmia-associated transcription factor isoform 90202
huntingtin isoform 2450045
Voltage-dependent L-type calcium channel subunit alpha-1C011011
Solute carrier organic anion transporter family member 1A407015
Voltage-dependent L-type calcium channel subunit alpha-1F025025
Lysine-specific demethylase PHF20101
Thyroid hormone receptor alpha0101
ATP-dependent translocase ABCB1017017
Muscarinic acetylcholine receptor M2050661
Muscarinic acetylcholine receptor M4050559
Beta-1 adrenergic receptor021627
Muscarinic acetylcholine receptor M5045453
Thyroid hormone receptor alpha0549
Thyroid hormone receptor beta0549
Muscarinic acetylcholine receptor M1050762
Beta-3 adrenergic receptor016521
D(2) dopamine receptor042351
Lethal factor0303
Alpha-2B adrenergic receptor060566
Thyroid hormone receptor beta0303
Muscarinic acetylcholine receptor M3048759
ATP-dependent translocase ABCB1018322
Substance-K receptor024024
D(1A) dopamine receptor035240
D(4) dopamine receptor027133
Carnitine O-palmitoyltransferase 2, mitochondrial0303
Histamine H2 receptor027229
Endothelin-1 receptor09110
Lysine-specific demethylase 5A0404
B2 bradykinin receptor0619
Melanocortin receptor 40606
C-8 sterol isomerase0404
Melanocortin receptor 5010010
Sodium channel protein type 1 subunit alpha0808
Sodium channel protein type 4 subunit alpha09010
Squalene synthase0102
C-C chemokine receptor type 20808
Melanocortin receptor 30606
Carnitine O-palmitoyltransferase 1, liver isoform0303
C-C chemokine receptor type 40505
Sodium channel protein type 7 subunit alpha0707
Voltage-dependent L-type calcium channel subunit alpha-1D 025025
Voltage-dependent L-type calcium channel subunit alpha-1S025025
Squalene monooxygenase0101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0516
Sodium channel protein type 9 subunit alpha010010
Lysine-specific demethylase 7A0101
Carnitine O-palmitoyltransferase 1, muscle isoform0202
Sodium channel protein type 2 subunit alpha0909
Sigma non-opioid intracellular receptor 1047249
NAD-dependent protein deacetylase sirtuin-3, mitochondrial0448
Sodium channel protein type 3 subunit alpha010010
Sodium channel protein type 11 subunit alpha0606
Histone lysine demethylase PHF80101
Sodium channel protein type 8 subunit alpha0707
Sodium channel protein type 10 subunit alpha0606
tumor necrosis factor7007
Chain A, Mutant Al2 6e7p9g0011
Beta-lactamase 0208
Beta-lactamase 0207
Beta-lactamase 0007
Metallo-beta-lactamase type 20019
Metallo-beta-lactamase VIM-11 0008
Metallo-beta-lactamase VIM-20008
Beta-lactamase 0007
Metallo-beta-lactamase0008
Beta-lactamase 0207
Beta-lactamase OXA-70003
Beta-lactamase 0005
Beta-lactamase 0005
Beta-lactamase 0005
Solute carrier family 15 member 20808
Metallo-beta-lactamase VIM-130108
Efflux transporter 0104
Beta-lactamase 0006
Beta-lactamase Toho-10004
Beta-lactamase 0104
Class D beta-lactamase0002
Metallo-beta-lactamase0007
Beta-lactamase 0006
Beta-lactamase 0128
Metallo-b-lactamase 0009
Carbapenem-hydrolyzing beta-lactamase KPC0007
Beta-lactamase class B VIM-2 00110
Beta-lactamase VIM-1 0108
Chain A, Pol Polyprotein0011
Chain B, Pol Polyprotein0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, protease0101
Chain B, protease0101
Chain A, protease0101
Chain B, protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, gag-pro-pol polyprotein0101
Chain B, gag-pro-pol polyprotein0101
Chain A, gag-pro-pol polyprotein0101
Chain B, gag-pro-pol polyprotein0101
Chain A, gag-pro-pol polyprotein0101
Chain B, gag-pro-pol polyprotein0101
Gag-Pol polyprotein0404
Gag-Pol polyprotein0303
Gag-Pol polyprotein0101
Gag-Pol polyprotein0404
Gag polyprotein0101
Gag-Pol polyprotein0303
Cathepsin D0303
Gag-Pol polyprotein0516
Cytochrome P450 3A509111
Gag-Pol polyprotein0303
Thromboxane-A synthase0103
Protease 011420
Protease 08313
Amine oxidase [flavin-containing] A 011112
UDP-glucuronosyltransferase 1A408016
Nuclear factor NF-kappa-B p105 subunit0909
Hexokinase-20101
Bile acid receptor07815
Beta-glucuronidase0202
Cholinesterase020020
Gastrin/cholecystokinin type B receptor110214
Testosterone 17-beta-dehydrogenase 30808
Atrial natriuretic peptide receptor 30202
Type-1 angiotensin II receptor0011
Type-1 angiotensin II receptor010520
Ornithine decarboxylase0003
Tubulin beta-4A chain09517
Tubulin beta chain09517
Tubulin alpha-3C chain09517
Tubulin alpha-1B chain09517
Tubulin alpha-4A chain09517
Tubulin beta-4B chain09517
Tubulin beta-3 chain010518
Tubulin beta-2A chain09517
Tubulin beta-8 chain09517
Tubulin alpha-3E chain09517
Tubulin alpha-1A chain09517
Tubulin alpha-1C chain09517
Tubulin beta-6 chain09517
Tubulin beta-2B chain09517
Tubulin beta-1 chain09517
30S ribosomal protein S60617
30S ribosomal protein S70617
50S ribosomal protein L150617
50S ribosomal protein L100617
50S ribosomal protein L110617
50S ribosomal protein L7/L120617
50S ribosomal protein L190617
50S ribosomal protein L10617
50S ribosomal protein L200617
50S ribosomal protein L270617
50S ribosomal protein L280617
50S ribosomal protein L290617
50S ribosomal protein L310617
50S ribosomal protein L31 type B0617
50S ribosomal protein L320617
50S ribosomal protein L330617
50S ribosomal protein L340617
50S ribosomal protein L350617
50S ribosomal protein L360617
30S ribosomal protein S100617
30S ribosomal protein S110617
30S ribosomal protein S120617
30S ribosomal protein S130617
30S ribosomal protein S160617
30S ribosomal protein S180617
30S ribosomal protein S190617
30S ribosomal protein S200617
30S ribosomal protein S20617
30S ribosomal protein S30617
30S ribosomal protein S40617
30S ribosomal protein S50617
30S ribosomal protein S80617
30S ribosomal protein S90617
50S ribosomal protein L130617
50S ribosomal protein L140617
50S ribosomal protein L160617
50S ribosomal protein L230617
30S ribosomal protein S150617
50S ribosomal protein L170617
50S ribosomal protein L210617
50S ribosomal protein L300617
50S ribosomal protein L60617
30S ribosomal protein S140617
30S ribosomal protein S170617
30S ribosomal protein S10617
50S ribosomal protein L180617
50S ribosomal protein L20617
50S ribosomal protein L30617
50S ribosomal protein L240617
50S ribosomal protein L40617
50S ribosomal protein L220617
50S ribosomal protein L50617
30S ribosomal protein S210617
50S ribosomal protein L250617
50S ribosomal protein L36 20617
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0303
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0303
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0303
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0303
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0303
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0303
Chain A, Transthyretin0033
Chain A, Transthyretin0033
Chain A, Transthyretin0033
Chain A, Transthyretin0033
Chain B, Transthyretin0033
Chain A, Transthyretin0033
Chain B, Transthyretin0033
Chain A, Casein kinase II subunit alpha0202
Chain A, Casein kinase II subunit alpha0202
Chain A, Casein Kinase Ii Subunit Alpha0202
RGS125005
pyruvate kinase180018
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 14004
Aldo-keto reductase family 1 member B10015015
Poly [ADP-ribose] polymerase tankyrase-10516
Lysozyme C-10101
Estrogen receptor1351151
Myeloperoxidase013013
Beta-glucuronidase0202
Seed linoleate 13S-lipoxygenase-1014020
Sialidase0707
Angiotensin-converting enzyme028028
Cystic fibrosis transmembrane conductance regulator0156
17-beta-hydroxysteroid dehydrogenase type 10607
Aldo-keto reductase family 1 member B1032033
Mucin-10101
Substance-P receptor015018
Multidrug resistance-associated protein 1 013119
17-beta-hydroxysteroid dehydrogenase type 20808
Peroxisome proliferator-activated receptor gamma01910
Homeobox protein Nkx-2.5 0202
Estrogen receptor0022
Lactoperoxidase0307
MO15-related protein kinase Pfmrk 0404
Transcription factor GATA-4 0202
Substance-K receptor011011
Casein kinase II subunit alpha 3011011
Estrogen receptor beta126937
NACHT, LRR and PYD domains-containing protein 3 0303
Myocilin0011
Prenyltransferase homolog0004
Poly [ADP-ribose] polymerase tankyrase-20639
Carboxylic ester hydrolase 0304
NADPH oxidase 40404
Estrogen receptor beta0022
Short transient receptor potential channel 50606
Sialidase-2010010
2,3-bisphosphoglycerate-independent phosphoglycerate mutase8008
Substance-P receptor08210
Neuromedin-K receptor0213
Substance-P receptor0101
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0022
Chain A, SERUM ALBUMIN0022
Fatty-acid amide hydrolase 10505
Calmodulin 0236
Lanosterol 14-alpha demethylase09211
Solute carrier organic anion transporter family member 1B3034044
Cytosolic phospholipase A2 gamma0303
Transient receptor potential cation channel subfamily V member 20415
Solute carrier organic anion transporter family member 1B1037048
Cytosolic phospholipase A2 0101
Cytosolic phospholipase A2 beta0101
Platelet-activating factor acetylhydrolase0305
Monoglyceride lipase0303
Muscarinic acetylcholine receptor M1024736
Muscarinic acetylcholine receptor M3021732
Muscarinic acetylcholine receptor M4022632
Muscarinic acetylcholine receptor M5021631
Muscarinic acetylcholine receptor M2022734
Muscarinic acetylcholine receptor M10237
Muscarinic acetylcholine receptor0719
Muscarinic acetylcholine receptor M30037
Muscarinic acetylcholine receptor M20017
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Nitric oxide synthase, endothelial0103
Nitric oxide synthase, inducible0708
Cationic amino acid transporter 30202
Vasopressin V2 receptor0427
Oxytocin receptor0336
Vasopressin V1a receptor0134
Vasopressin V1a receptor08311
Vasopressin V1b receptor0224
Vasopressin V2 receptor0011
Vasopressin V1b receptor0214
Translocator protein0203
Oxytocin receptor0213
Vasopressin V2 receptor 0213
Integrin beta-10404
Integrin alpha-V 0202
Integrin alpha-50101
Integrin beta-50101
G protein-coupled receptor kinase 6013536
MAP kinase-activated protein kinase 3001414
Uncharacterized aarF domain-containing protein kinase 5003030
Chain A, Hyaluronidase, phage associated0101
Pancreatic alpha-amylase0202
Albumin0203
Urease0506
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0909
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20034
Prolyl hydroxylase EGLN30034
Hypoxia-inducible factor 1-alpha inhibitor0102
Solute carrier family 23 member 10101
Neutral amino acid transporter A0505
Neutral amino acid transporter B(0)0505
Carbonic anhydrase-like protein, putative0009
Amino acid transporter0505
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0202
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Glutamate receptor ionotropic, NMDA 2D020532
Glutamate receptor ionotropic, NMDA 3B020532
Glutamate receptor ionotropic, NMDA 3A020532
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0044
ras protein, partial0044
Rac1 protein0044
cell division cycle 42 (GTP binding protein, 25kDa), partial0044
Prostaglandin-H2 D-isomerase0202
Prostaglandin G/H synthase 2 0709
Fatty acid-binding protein, liver09110
Glutathione hydrolase 1 proenzyme0101
Urotensin-2 receptor0202
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0044
Rho-associated protein kinase 20303
Solute carrier family 22 member 20010010
Solute carrier family 22 member 6010010
Sigma non-opioid intracellular receptor 1012315
Beta-1 adrenergic receptor 02610
Beta-2 adrenergic receptor016724
Beta-2 adrenergic receptor03510
Solute carrier organic anion transporter family member 2B1 010014
Insulin receptor 0505
Dipeptidyl peptidase 40101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0606
Atrial natriuretic peptide receptor 10112
Atrial natriuretic peptide receptor 1 0011
cystic fibrosis transmembrane conductance regulator0404
short transient receptor potential channel 6 isoform 10022
Muscarinic acetylcholine receptor M40315
5-hydroxytryptamine receptor 7018018
PINK1120012
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial0101
Cytochrome c oxidase subunit NDUFA40101
Acyl carrier protein, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10101
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 30101
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 0101
NADH dehydrogenase [ubiquinone] iron-sulfur protein 50101
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial0101
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial0101
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10101
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 60101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 30101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 70101
NADH dehydrogenase [ubiquinone] 1 subunit C20101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 100101
NADH-ubiquinone oxidoreductase chain 10101
NADH-ubiquinone oxidoreductase chain 20101
NADH-ubiquinone oxidoreductase chain 30101
NADH-ubiquinone oxidoreductase chain 4L0101
NADH-ubiquinone oxidoreductase chain 40102
NADH-ubiquinone oxidoreductase chain 50101
NADH-ubiquinone oxidoreductase chain 60101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 70101
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial0101
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial0101
Melatonin receptor type 1A0426
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 80101
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 60101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 50101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial0101
Amine oxidase [flavin-containing] A0303
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 110101
Amine oxidase [flavin-containing] B0404
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 20101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 30101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 20101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 40101
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 120101
Complex I intermediate-associated protein 30, mitochondrial0101
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 90101
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 20202
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha104142
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B001313
Histone-lysine N-methyltransferase SMYD30101
N-lysine methyltransferase SMYD20415
DNA (cytosine-5)-methyltransferase 10707
Multidrug and toxin extrusion protein 1032032
Protein-arginine deiminase type-4010010
Fibroblast growth factor receptor 40101
Gamma-aminobutyric acid type B receptor subunit 20224
Gamma-aminobutyric acid type B receptor subunit 20303
Gamma-aminobutyric acid type B receptor subunit 10224
Gamma-aminobutyric acid type B receptor subunit 10202
dual specificity tyrosine-phosphorylation-regulated kinase 1A0006
Lysine-specific histone demethylase 1A019019
Progesterone receptor013521
Fructose-1,6-bisphosphatase 10404
Lysosomal alpha-glucosidase0202
Sucrase-isomaltase, intestinal0202
Cytochrome P450 11B1, mitochondrial0303
Sucrase-isomaltase, intestinal0404
Sodium- and chloride-dependent GABA transporter 10808
Sodium- and chloride-dependent GABA transporter 20707
Sodium- and chloride-dependent GABA transporter 30707
Prostaglandin G/H synthase 2 09011
Linoleate 9S-lipoxygenase-40202
1-deoxy-D-xylulose 5-phosphate reductoisomerase0404
Sodium- and chloride-dependent betaine transporter0707
Prolyl endopeptidase0606
4-aminobutyrate aminotransferase, mitochondrial0203
Lactoylglutathione lyase013013
Receptor-type tyrosine-protein phosphatase S0101
Prostaglandin G/H synthase 1 010012
Polyunsaturated fatty acid lipoxygenase ALOX15B0101
G-protein coupled receptor 3508816
Canalicular multispecific organic anion transporter 10507
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase0101
Nuclear factor erythroid 2-related factor 20001
Ubiquitin carboxyl-terminal hydrolase 20505
Ghrelin O-acyltransferase0101
Nuclear factor erythroid 2-related factor 201610
Ubiquitin carboxyl-terminal hydrolase 70314
Ghrelin O-acyltransferase0404
5-hydroxytryptamine receptor 3E09314
5-hydroxytryptamine receptor 3B010416
Interstitial collagenase015219
Low affinity immunoglobulin epsilon Fc receptor0101
Matrilysin0909
Neutrophil collagenase0606
Metabotropic glutamate receptor 50325
Collagenase 3010012
5-hydroxytryptamine receptor 3A014420
Matrix metalloproteinase-140505
Snake venom metalloproteinase BaP10101
5-hydroxytryptamine receptor 3D09314
5-hydroxytryptamine receptor 3C09314
Nuclear factor NF-kappa-B p100 subunit 0707
Transcription factor p65011011
NACHT, LRR and PYD domains-containing protein 3 0606
Class A sortase SrtA 0202
Voltage-dependent L-type calcium channel subunit alpha-1C010011
Voltage-dependent L-type calcium channel subunit alpha-1D0708
Voltage-dependent L-type calcium channel subunit alpha-1S0708
Transient receptor potential cation channel subfamily A member 10077
Angiotensin-converting enzyme 011012
Liver carboxylesterase 108013
Angiotensin-converting enzyme0516
Chain A, Integrase0101
Chain A, Integrase0101
Chain A, T4 LYSOZYME0011
Chain A, GCN4P10011
Chain B, GCN4P10011
Chain C, GCN4P10011
Chain A, T4 LYSOZYME0011
Chain A, T4 LYSOZYME0011
Chain A, Replicase polyprotein 1ab0101
Chain A, 3C-like proteinase0101
Endolysin0033
Chain A, Oxygen-insensitive Nad(p)h Nitroreductase0101
Chain B, Oxygen-insensitive Nad(p)h Nitroreductase0101
D-amino-acid oxidase0112
D-amino-acid oxidase0314
Metabotropic glutamate receptor 50124
Alpha-glucosidase MAL120404
Monocarboxylate transporter 10104
D-aspartate oxidase0202
Serine racemase0202
Transient receptor potential cation channel subfamily V member 105413
Proteasome subunit beta type-110506
Calpain-90101
Proteasome subunit alpha type-70506
Cathepsin B0606
Calpain-2 catalytic subunit0303
Proteasome subunit beta type-109011
Proteasome subunit alpha type-10506
Proteasome subunit alpha type-20506
Proteasome subunit alpha type-30506
Proteasome subunit alpha type-40506
NF-kappa-B inhibitor alpha0011
Proteasome subunit beta type-80506
Proteasome subunit beta type-90506
Proteasome subunit alpha type-50506
Proteasome subunit beta type-40506
Proteasome subunit beta type-60506
Proteasome subunit beta type-100506
Cathepsin K0101
Proteasome subunit beta type-30506
Proteasome subunit beta type-209011
Proteasome subunit alpha type-60528
Proteasome subunit alpha-type 80506
Proteasome subunit beta type-70506
Gamma-secretase subunit PEN-20202
Acetylcholinesterase019020
Neuraminidase0303
Neuraminidase0404
Aldo-keto reductase family 1 member C3010010
Aldo-keto reductase family 1 member C2 0505
core protein, partial0101
Sodium- and chloride-dependent GABA transporter 10202
Sodium- and chloride-dependent GABA transporter 20303
Sodium- and chloride-dependent GABA transporter 30303
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 20202
galactokinase6006
Cocaine esterase0809
Tyrosyl-DNA phosphodiesterase 20202
NAD0207
NADPH--cytochrome P450 reductase0101
Protein-glutamine gamma-glutamyltransferase 20303
Caspase-1110012
M-phase inducer phosphatase 10505
Receptor-type tyrosine-protein phosphatase eta0303
Receptor protein-tyrosine kinase 0404
Single-stranded DNA cytosine deaminase9009
Mucosa-associated lymphoid tissue lymphoma translocation protein 10202
phosphoglycerate kinase160016
LMP1 [Human herpesvirus 4]0006
Protein skinhead-10101
Quinone oxidoreductase00010
NAD(P)H dehydrogenase [quinone] 10006
Chain A, D-MALTODEXTRIN BINDING PROTEIN0011
Chain A, Limit Dextrinase0011
Chain A, Solute-binding protein0011
Chain A, Solute-binding protein0011
Chain B, SusD0011
Chain A, SusD0011
Chain A, SusD0011
Chain A, Alpha-hemolysin0011
Chain B, Alpha-hemolysin0011
Chain C, Alpha-hemolysin0011
Chain D, Alpha-hemolysin0011
Chain E, Alpha-hemolysin0011
Chain F, Alpha-hemolysin0011
Chain G, Alpha-hemolysin0011
Chain A, Betaine ABC transporter permease and substrate binding protein0011
Chain A, Osmoprotection protein (ProX)0011
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Chain A, Glycine betaine/carnitine/choline-binding protein0022
Ubiquitin-like modifier activating enzyme 20202
SUMO1 activating enzyme subunit 10202
SUMO-conjugating enzyme UBC90202
Pancreatic alpha-amylase0507
DNA polymerase beta0505
DNA polymerase beta0303
Zinc finger protein GLI10202
5'-nucleotidase0202
5'-nucleotidase0202
Env polyprotein 0033
Phosphodiesterase isozyme 4 0101
Transmembrane prolyl 4-hydroxylase0134
Non-structural protein 1 0202
Cytochrome P450 26A10202
Cytochrome P450 26B10101
Transcription initiation factor TFIID subunit 10112
Nucleosome-remodeling factor subunit BPTF0011
Bromodomain testis-specific protein0134
Ribosomal protein S6 kinase alpha-10101
Serine/threonine-protein kinase VRK10101
Cytochrome P450 2E10404
Dipeptidyl peptidase 10202
STAT3, partial0314
signal transducer and activator of transcription 1-alpha/beta isoform alpha0314
transcription factor p65 isoform 10022
Estrogen receptor beta0124
Triosephosphate isomerase0202
Carbonyl reductase [NADPH] 10608
Estrogen receptor0124
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)0808
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
nonstructural protein 10404
green fluorescent protein, partial0101
insulin-degrading enzyme isoform 10011
Receptor-type tyrosine-protein phosphatase beta0002
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
GTPase KRas0112
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1012113
Estrogen-related receptor gamma0213
GTP-binding protein Rheb0011
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
26S proteasome non-ATPase regulatory subunit 110202
26S proteasome non-ATPase regulatory subunit 120202
26S proteasome non-ATPase regulatory subunit 140303
26S proteasome non-ATPase regulatory subunit 30202
Prothrombin07413
Chymotrypsinogen A0809
Cathepsin G0404
Lysosomal protective protein0202
Chymotrypsinogen B0303
26S proteasome regulatory subunit 6A0202
Chymase0101
Proteasome subunit beta type-80101
26S proteasome regulatory subunit 70202
Lon protease homolog, mitochondrial0101
26S proteasome non-ATPase regulatory subunit 80202
26S proteasome non-ATPase regulatory subunit 70202
26S proteasome non-ATPase regulatory subunit 40202
26S proteasome complex subunit SEM10202
26S proteasome regulatory subunit 40202
26S proteasome regulatory subunit 80202
26S proteasome regulatory subunit 10B0202
26S proteasome non-ATPase regulatory subunit 20202
26S proteasome non-ATPase regulatory subunit 60202
Proteasomal ubiquitin receptor ADRM10202
ATP-dependent Clp protease proteolytic subunit0224
26S proteasome non-ATPase regulatory subunit 10202
26S proteasome non-ATPase regulatory subunit 130202
Endothelin receptor type B5308
Endothelin receptor type B0415
Endothelin-1 receptor5218
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter09111
Endothelin-1 receptor0101
Nucleophosmin0303
Glycogen phosphorylase, muscle form0101
Tyrosine-protein kinase Blk0202
Platelet-derived growth factor receptor alpha0202
Platelet-derived growth factor receptor beta0202
B2 bradykinin receptor0101
B1 bradykinin receptor0101
major prion protein preproprotein Prp precursor0202
Thymidine kinase0304
Nuclear hormone receptor family member daf-120011
oxysterols receptor LXR-beta isoform 10011
Thymidine phosphorylase0208
Thymidylate kinase0202
Thymidine kinase0005
Cytochrome P450 3A70101
Chain A, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0202
Serine/threonine-protein kinase mTOR 0202
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0303
Potassium channel subfamily K member 30505
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 90101
Chain A, Nitrile Hydratase alpha subunit0101
Chain B, Nitrile Hydratase beta subunit0101
Methyl-accepting chemotaxis protein NahY0033
Aldo-keto reductase family 1 member A10202
Aldo-keto reductase family 1 member C40404
Aldo-keto reductase family 1 member C10404
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0022
Chain A, glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Glycogen phosphorylase, liver form0022
Chain A, Chitinase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Vasopressin V2 receptor0002
Adenosine receptor A2a0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
Adenylate cyclase type 10002
Chitotriosidase-10202
Adenosine receptor A2b0103
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0202
Palmitoleoyl-protein carboxylesterase NOTUM0235
Endochitinase B10202
Phosphodiesterase 0202
Guanine deaminase0203
electroneutral potassium-chloride cotransporter KCC20011
TSHR protein4004
LacZ protein (plasmid)0022
XBP10101
type-1 angiotensin II receptor0202
apelin receptor0303
heat shock protein HSP 90-alpha isoform 204011
DNA damage-inducible transcript 3 protein0101
heat shock protein 90, putative0007
Chain A, Vitamin D Nuclear Receptor0011
Vitamin D3 receptor0011
Vitamin D-binding protein0011
Vitamin D3 receptor091022
Vitamin D3 receptor0113
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0213
Vitamin D3 receptor0112
Transporter0505
Vitamin D3 receptor A0022
DNA topoisomerase 0101
putative alpha-glucosidase1001
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
relaxin receptor 1 isoform 13003
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
DNA ligase0202
Heterogeneous nuclear ribonucleoprotein A10022
Type-2 restriction enzyme BamHI0101
Somatostatin receptor type 10202
Somatostatin receptor type 20202
Somatostatin receptor type 40202
Somatostatin receptor type 30202
Somatostatin receptor type 50202
Type-2 restriction enzyme HindIII0101
Ribonuclease pancreatic0101
DNA topoisomerase 10203
DNA topoisomerase 10101
DNA topoisomerase type IB small subunit 0011
Leukotriene B4 receptor 21136
Protein phosphatase 1B0101
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit0101
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B 0101
Chain A, Beta-lactoglobulin0011
Chain A, Beta-lactoglobulin0011
UDP-3-O-acyl-N-acetylglucosamine deacetylase0011
transient receptor potential cation channel subfamily V member 15005
Transient receptor potential cation channel subfamily V member 10628
NADH-ubiquinone oxidoreductase chain 10202
Cannabinoid receptor 10314
Cannabinoid receptor 2 0303
Corticotropin-releasing factor receptor 20101
Transient receptor potential cation channel subfamily V member 40112
Neuronal acetylcholine receptor subunit alpha-307311
Neuronal acetylcholine receptor subunit alpha-20528
Neuronal acetylcholine receptor subunit beta-30438
Neuronal acetylcholine receptor subunit beta-407311
Neuronal acetylcholine receptor subunit alpha-50427
Neuronal acetylcholine receptor subunit alpha-60539
Neuronal acetylcholine receptor subunit alpha-90427
Neuronal acetylcholine receptor subunit alpha-100427
Chain A, serum paraoxonase0101
Proteasome subunit beta type-20101
Proteasome subunit beta type-10101
Glutathione S-transferase omega-10505
luciferase5005
Tyrosine-protein phosphatase 10202
C-terminal-binding protein 15005
Acid ceramidase0101
Acid ceramidase0101
Sulfide:quinone oxidoreductase, mitochondrial0101
Glutathione reductase0303
Solute carrier family 22 member 50001
Solute carrier family 22 member 50102
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Chain A, Protein kinase CK2, alpha Subunit0101
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT0101
Chain A, Protein Kinase Ck2, Alpha Subunit0101
Serine/threonine-protein kinase Sgk10101
Melatonin receptor type 1B0325
Dihydroorotate dehydrogenase 0909
Chain A, Neutrophil gelatinase-associated lipocalin0011
3-dehydroquinate synthase0203
Prolyl 4-hydroxylase subunit alpha-10606
Potassium-transporting ATPase subunit beta0203
Potassium-transporting ATPase alpha chain 10203
Autoinducer 2-binding periplasmic protein LuxP0303
E3 ubiquitin-protein ligase Mdm21719
Glutaminyl-peptide cyclotransferase0505
Arginase-10101
Glutaminase kidney isoform, mitochondrial0101
Glutaminase kidney isoform, mitochondrial0112
Solute carrier family 22 member 1107014
Solute carrier family 22 member 809012
Beta-lactamase 0005
Beta-lactamase 0105
Beta-lactamase 0002
Beta-lactamase 0006
Metallo-beta-lactamase VIM-19 0006
Beta-lactamase 0004
Beta-lactamase0002
Beta-lactamase0003
Beta-lactamase0208
Beta-lactamase SHV-10006
Beta-lactamase0002
Beta-lactamase0007
Beta-lactamase TEM0308
Beta-lactamase0002
B2 metallo-beta-lactamase 0006
Beta-lactamase 0004
Metallo-beta-lactamase VIM-20007
Beta-lactamase 0004
Beta-lactamase 0004
BlaVIM-1 0006
Beta-lactamase 0006
Beta-lactamase 0003
Beta-lactamase 0005
Solute carrier family 22 member 80709
Insulin-degrading enzyme0303
Glutathione peroxidase 10101
Microsomal glutathione S-transferase 10101
Solute carrier family 22 member 705010
Solute carrier family 22 member 70408
Beta-lactamase 0006
Beta-lactamase 0002
Beta-lactamase 0104
Beta-lactamase SHV-10003
Beta-lactamase 0002
Beta-lactamase 0003
Beta-lactamase 0003
L-ornithine N(5)-monooxygenase0112
Ubiquitin carboxyl-terminal hydrolase isozyme L10202
Ubiquitin carboxyl-terminal hydrolase isozyme L30202
Tyrosine-protein phosphatase non-receptor type 20606
Receptor-type tyrosine-protein phosphatase epsilon0303
Tyrosine-protein phosphatase non-receptor type 60505
Tyrosine-protein phosphatase non-receptor type 70202
Tryptophan 2,3-dioxygenase0405
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN0101
Heat shock factor protein 10213
Tyrosine-protein phosphatase non-receptor type 110405
Regulator of G-protein signaling 170202
Ubiquitin carboxyl-terminal hydrolase 150101
Ubiquitin carboxyl-terminal hydrolase isozyme L50101
Chain A, Carbonic anhydrase II0101
Prostaglandin E synthase0707
Cytochrome c oxidase subunit 10202
Cytochrome c oxidase subunit 20101
Catechol O-methyltransferase0101
Cytochrome c oxidase subunit 20606
Quinolone resistance protein NorA0607
Prostaglandin G/H synthase 10505
Cruzipain0808
Sodium/hydrogen exchanger 10101
Indoleamine 2,3-dioxygenase 10808
Bifunctional epoxide hydrolase 2015015
Prostaglandin G/H synthase 2010011
Prostaglandin G/H synthase 10101
Cyclooxygenase-2 0202
P2Y purinoceptor 120314
Beta-lactamase 0002
DNA (cytosine-5)-methyltransferase 1 isoform b0101
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 10505
Beta-lactamase OXA-10001
Beta-lactamase 0002
Caspase-20022
perilipin-50808
perilipin-10808
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0808
Thioredoxin reductase 1, cytoplasmic0202
Dihydrofolate reductase019022
Acetylcholinesterase0303
Tumor necrosis factor receptor superfamily member 1A0101
Stromal cell-derived factor 10101
Sortase A0202
Alpha-2C adrenergic receptor046754
Ileal sodium/bile acid cotransporter0608
Bile acid receptor0123
Dihydroxyacetone phosphate acyltransferase0002
Methionine--tRNA ligase, mitochondrial0011
Gamma-aminobutyric acid receptor subunit alpha-10608
Gamma-aminobutyric acid receptor subunit beta-10608
Gamma-aminobutyric acid receptor subunit alpha-20608
Gamma-aminobutyric acid receptor subunit alpha-30608
Gamma-aminobutyric acid receptor subunit alpha-40608
Gamma-aminobutyric acid receptor subunit gamma-20608
Cholecystokinin receptor type A112013
Histamine H1 receptor029536
Chain A, BCL-2-RELATED PROTEIN A10067
heat shock protein 900044
calcineurin A1, putative0022
hepatocyte nuclear factor 4-alpha isoform 20202
ubiquitin-conjugating enzyme E2 N0606
protein AF-9 isoform a0004
melanocortin receptor 40213
CAAX prenyl protease0002
bcl-2-related protein A10404
glycogen synthase kinase-3 alpha0005
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0004
bcl-2-like protein 11 isoform 10066
Synaptojanin-20101
Solute carrier family 22 member 2020026
Synaptojanin-10101
Solute carrier family 22 member 3013015
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 2015015
Spermine oxidase0101
1,3-beta-D-glucan synthase catalytic subunit 0101
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0505
glucose-6-phosphate 1-dehydrogenase isoform b0505
Dihydrofolate reductase 0404
Riboflavin-binding protein0235
Major prion protein0044
Histidine-rich protein PFHRP-II0405
Spike glycoprotein0224
DNA ligase 10101
Calcium-dependent protein kinase 10011
DNA ligase A0101
Sigma intracellular receptor 20606
Phosphoethanolamine N-methyltransferase0101
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
NADPH oxidase 10101
Snq2p0003
Adenylate cyclase type 1 0404
Glutamate receptor ionotropic, NMDA 2D0516
Glutamate receptor ionotropic, NMDA 3B0516
Albumin0088
Major prion protein0112
Cys-loop ligand-gated ion channel0101
Sphingomyelin phosphodiesterase0101
D017018
D(3) dopamine receptor019019
D(2) dopamine receptor0707
D(1B) dopamine receptor0508
Adenylate cyclase type 30404
Sodium-dependent dopamine transporter019221
D(1B) dopamine receptor012012
Adenylate cyclase type 20404
Adenylate cyclase type 40404
D(4) dopamine receptor013013
Histamine H1 receptor05511
Pleiotropic ABC efflux transporter of multiple drugs0306
Adenylate cyclase type 80404
Gastrin/cholecystokinin type B receptor0606
Aldehyde oxidase 10303
Adenylate cyclase type 60404
Adenylate cyclase type 50404
Glutamate receptor ionotropic, NMDA 109110
Aldehyde oxidase09011
Glutamate receptor ionotropic, NMDA 2A09110
Glutamate receptor ionotropic, NMDA 2B08210
Glutamate receptor ionotropic, NMDA 2C0516
Nuclear receptor subfamily 3 group C member 3 023023
Adenylyl cyclase 7 0404
Glutamate receptor ionotropic, NMDA 3A0516
D0505
Histamine H3 receptor07210
LAP40011
RPL19A0022
Cholesterol 24-hydroxylase0235
Phospholipase A20314
G-protein coupled bile acid receptor 10101
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Acetylcholinesterase0022
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10304
Solute carrier family 22 member 20202
Sodium- and chloride-dependent creatine transporter 10101
Solute carrier family 22 member 1013018
High affinity choline transporter 10101
Solute carrier family 22 member 2012014
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)]0101
Peroxisome proliferator-activated receptor alpha77823
Potassium-transporting ATPase alpha chain 10202
Potassium-transporting ATPase subunit beta0202
Histamine H4 receptor0639
Solute carrier family 22 member 40101
Extracellular calcium-sensing receptor0011
shiga toxin 1 variant A subunit1001
shiga toxin 1 B subunit1001
Cell division protein FtsZ0115
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0407
DNA gyrase subunit B0407
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
DNA gyrase subunit A0102
Multidrug resistance protein MdtK0011
DNA gyrase subunit B0506
DNA gyrase subunit A0607
Enoyl-[acyl-carrier-protein] reductase [NADH]0409
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Dipeptidyl peptidase 40303
Neutral alpha-glucosidase AB0101
5-hydroxytryptamine receptor 2A0101
Heparanase0033
Sodium-dependent noradrenaline transporter0202
Tryptophan 5-hydroxylase 10202
Aldo-keto reductase family 1 member B10707
Aromatase0101
Sodium-dependent serotonin transporter0202
Sodium-dependent dopamine transporter0202
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Beta-lactamase0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0203
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Transient receptor potential cation channel subfamily M member 80213
mitogen-activated protein kinase kinase kinase kinase 2 isoform 10011
mitogen-activated protein kinase kinase kinase 3 isoform 10011
Translocator protein0202
Translocator protein0629
Alpha-1B adrenergic receptor 0033
Membrane primary amine oxidase 0202
5-hydroxytryptamine receptor 3A0224
Alpha-2B adrenergic receptor0103
Alpha-2C adrenergic receptor0103
Alpha-2A adrenergic receptor0103
Alpha-2A adrenergic receptor0101
Nischarin0303
Nischarin0303
P2Y purinoceptor 120404
Beta-2 adrenergic receptor09111
Beta-1 adrenergic receptor010315
5-hydroxytryptamine receptor 3A0707
Beta-3 adrenergic receptor0617
Histamine H1 receptor09211
5-hydroxytryptamine receptor 2C 0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 5A0404
D(2) dopamine receptor0202
D(3) dopamine receptor0202
D(2) dopamine receptor0101
5-hydroxytryptamine receptor 2B0202
Cholecystokinin receptor type A0707
5-hydroxytryptamine receptor 1A0202
Cytochrome P450 2D10202
Cytochrome P450 2D260303
Cytochrome P450 2D30303
UDP-glucuronosyltransferase 2B709020
Kappa-type opioid receptor0529
Mu-type opioid receptor07212
Cytochrome P450 2D40303
Mas-related G-protein coupled receptor member X20055
Plasma kallikrein0208
Vesicular acetylcholine transporter0101
Tubulin polymerization-promoting protein0011
B2 bradykinin receptor0404
Dihydrofolate reductase0202
Beta-galactosidase0203
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20202
PH domain leucine-rich repeat-containing protein phosphatase 20101
Chymotrypsin-C0202
TPA: protein transporter TIM230303
Sterol 14-alpha demethylase0213
Squalene monooxygenase 0607
Solute carrier family 22 member 30202
Mineralocorticoid receptor 110518
Solute carrier organic anion transporter family member 1A106014
Exportin-10202
NAD-dependent histone deacetylase SIR20305
Amine oxidase [flavin-containing] B013013
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal0202
UDP-glucuronosyltransferase 2B10 0707
Sorbitol dehydrogenase0303
Induced myeloid leukemia cell differentiation protein Mcl-1012113
Zn finger protein 0101
Sodium- and chloride-dependent creatine transporter 10101
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 20101
Sodium-dependent phosphate transport protein 2B0101
Tyrosine-protein kinase ABL10404
HLA class II histocompatibility antigen gamma chain0101
ALK tyrosine kinase receptor0101
Angiopoietin-1 receptor0101
Lysine--tRNA ligase0101
Macrophage-stimulating protein receptor0101
Mixed lineage kinase domain-like protein0011
Echinoderm microtubule-associated protein-like 40101
Aurora kinase A-interacting protein0202
alkaline phosphatase, intestinal0123
toll-like receptor 90101
TPA: protein transporter TIM100505
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0213
intestinal alkaline phosphatase precursor0213
alkaline phosphatase, germ cell type preproprotein0123
Neuronal proto-oncogene tyrosine-protein kinase Src 0102
Heme oxygenase 1 0505
Glutathione S-transferase P0404
Microtubule-associated protein tau08110
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0101
Aminopeptidase N0505
Aminopeptidase N0404
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20303
Heme oxygenase 20404
Thioredoxin reductase 1, cytoplasmic0405
Thioredoxin reductase 30303
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30303
Cysteine protease 0303
Thioredoxin reductase 2, mitochondrial0303
Lymphocyte antigen 960022
Beta lactamase (plasmid)0202
Platelet-activating factor receptor0303
Phosphodiesterase 0303
Multidrug resistance-associated protein 50102
COUP transcription factor 2 isoform a0101
Glucose transporter0202
Hexose transporter 1 0202
Solute carrier family 2, facilitated glucose transporter member 10606
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0628
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
Integrin alpha-40303
Smoothened homolog0213
Sonic hedgehog protein0203
Sonic hedgehog protein0415
Smoothened homolog0639
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0404
nuclear receptor coactivator 3 isoform a0404
Thymidine kinase 2, mitochondrial0101
Thymidylate synthase08011
Thymidine kinase0101
Probable deoxycytidylate deaminase0002
Cytidine deaminase0205
Enoyl-[acyl-carrier-protein] reductase [NADH] 0404
Deoxynucleoside kinase0101
Chain A, Glucose-1-phosphate cytidylyltransferase0101
Chain B, CTP synthase0101
P2Y purinoceptor 20134
Glucose-1-phosphate cytidylyltransferase0101
neutrophil cytosol factor 10404
Solute carrier family 2, facilitated glucose transporter member 30101
Solute carrier family 2, facilitated glucose transporter member 40101
Deoxycytidine kinase0001
Alpha-tocopherol transfer protein0011
Coagulation factor X0404
Coagulation factor XII0505
Serine protease hepsin0404
Isocitrate lyase0202
RAD510202
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Growth factor receptor-bound protein 20102
Pantothenate synthetase0303
Growth factor receptor-bound protein 2 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
rac GTPase-activating protein 1 isoform a0505
Aldehyde dehydrogenase, mitochondrial0213
Prothrombin 0303
Glandular kallikrein0101
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
Dihydrofolate reductase010010
Proto-oncogene tyrosine-protein kinase Src0527
Proto-oncogene tyrosine-protein kinase LCK 0202
Myelin transcription factor 10101
Breakpoint cluster region protein0101
NF-kappa-B essential modulator0101
runt-related transcription factor 1 isoform AML1b7007
core-binding factor subunit beta isoform 27007
Potassium voltage-gated channel subfamily E member 10101
exodeoxyribonuclease V subunit RecD0202
exodeoxyribonuclease V subunit RecB0202
exodeoxyribonuclease V subunit RecC0202
Flavin reductase (NADPH)0033
Deoxyhypusine hydroxylase0101
Solute carrier organic anion transporter family member 1A50009
Solute carrier organic anion transporter family member 1A20106
Solute carrier organic anion transporter family member 1A304011
ATP-binding cassette sub-family C member 110002
Solute carrier organic anion transporter family member 1A10002
Solute carrier organic anion transporter family member 1B20105
Nuclear receptor subfamily 1 group I member 20044
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Thymidine kinase 2 0101
AAA family ATPase 0002
AAA family ATPase 0001
Sterol O-acyltransferase 10202
Chain A, Dutpase0011
Chain A, Dutpase0011
Chain B, Dutpase0011
Chain A, Dutpase0011
Chain B, Dutpase0011
Gamma-aminobutyric acid 0213
Alpha-1-acid glycoprotein 10001
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit gamma-20213
Gamma-aminobutyric acid receptor subunit delta0213
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit alpha-30213
Gamma-aminobutyric acid receptor subunit gamma-30213
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50213
Gamma-aminobutyric acid receptor subunit pi0213
Sphingosine-1-phosphate lyase 10202
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit theta0213
Gamma-aminobutyric acid receptor subunit gamma-10213
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0505
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0314
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0303
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0303
Acetylcholinesterase0101
Interleukin-80303
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
C-X-C chemokine receptor type 10303
UDP-glucuronosyltransferase 1A30004
UDP-glucuronosyltransferase 1A70103
UDP-glucuronosyltransferase 1A100104
NAD0101
ATP phosphoribosyltransferase0202
Proprotein convertase subtilisin/kexin type 70202
UDP-glucose 4-epimerase0202
Cysteinyl leukotriene receptor 10404
Chain A, DigA160011
Chain A, DigA160011
Sodium/potassium-transporting ATPase subunit alpha-1 0809
Sodium/potassium-transporting ATPase subunit beta-10809
Sodium/potassium-transporting ATPase subunit alpha-30607
Sodium/potassium-transporting ATPase subunit beta-20607
Sodium/potassium-transporting ATPase subunit alpha-20809
Sodium/potassium-transporting ATPase subunit alpha-10303
Potassium-transporting ATPase alpha chain 20102
Sodium/potassium-transporting ATPase subunit beta-30607
Sodium/potassium-transporting ATPase subunit gamma0607
Sodium/potassium-transporting ATPase subunit alpha-40607
Solute carrier organic anion transporter family member 4C10205
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-3 0202
Sodium/potassium-transporting ATPase subunit beta-1 0202
Sodium/potassium-transporting ATPase subunit alpha-40202
Solute carrier organic anion transporter family member 4C10002
Solute carrier organic anion transporter family member 1A40001
Chain A, Sex Hormone-Binding Globulin0011
Progesterone receptor0101
Glucocorticoid receptor0427
Sex hormone-binding globulin0101
Androgen receptor0112
Mineralocorticoid receptor0101
Neuropeptide FF receptor 20001
Cereblon isoform 40707
Insulin-like growth factor-binding protein 50011
Thromboxane A2 receptor 0216
Prostaglandin E2 receptor EP1 subtype0325
Prostaglandin E2 receptor EP4 subtype0314
Prostaglandin F2-alpha receptor0202
Prostaglandin F2-alpha receptor0224
Prostaglandin E2 receptor EP3 subtype0325
Prostaglandin E2 receptor EP2 subtype0314
Prostaglandin F2-alpha receptor0011
Prostaglandin D2 receptor0101
Solute carrier organic anion transporter family member 2A10202
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 70001
Catechol O-methyltransferase0215
Histamine N-methyltransferase0102
Calcium release-activated calcium channel protein 10202
Protein orai-20101
Protein orai-30101
isocitrate dehydrogenase 1, partial9009
urokinase-type plasminogen activator isoform 1 preproprotein1001
90-kda heat shock protein beta HSP90 beta, partial0404
DNA polymerase III, partial100010
LANA0002
kelch-like ECH-associated protein 10003
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
3',5'-cyclic-AMP phosphodiesterase 0303
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha0101
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0112
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0202
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0404
Exopolyphosphatase PRUNE10101
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
Phosphodiesterase 0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
beta-2 adrenergic receptor8019
polypyrimidine tract-binding protein 1 isoform a1001
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase0202
Carbamate kinase0101
C-X-C chemokine receptor type 20303
Protein-lysine 6-oxidase0101
C-C chemokine receptor type 50326
Gasdermin-D0202
Lysyl oxidase homolog 30101
Lysyl oxidase homolog 40101
Gasdermin-D0202
Lysyl oxidase homolog 20101
hypothetical protein CAALFM_CR05890CA0002
H3 histone acetyltransferase0002
mu-type opioid receptor isoform MOR-10022
5-hydroxytryptamine receptor 2A0022
POU domain, class 2, transcription factor 10002
Kinesin-like protein KIF110303
Nucleotide-binding oligomerization domain-containing protein 20202
Amine oxidase [flavin-containing] A 0303
Acetylcholinesterase 0404
Cholinesterase0202
Acetylcholine receptor subunit epsilon0112
Acyl-CoA:cholesterol acyltransferase 0303
Carboxylic ester hydrolase 0404
5'-AMP-activated protein kinase subunit beta-20102
Bone morphogenetic protein 40101
5'-AMP-activated protein kinase subunit gamma-30102
5'-AMP-activated protein kinase subunit beta-10102
Uridine phosphorylase 10001
N-acetyltransferase Eis0303
DNA-(apurinic or apyrimidinic site) endonuclease0213
Ultraspiracle0202
20-hydroxy-ecdysone receptor 0202
Ecdysone receptor0101
replicative DNA helicase0002
recombinase A0022
UDP-glucuronosyltransferase 2B170001
Eyes absent homolog 20202
Beta-lactamase 0102
Beta-lactamase 0101
Chain A, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, POL POLYPROTEIN0101
Chain B, POL POLYPROTEIN0101
Chain A, Pol Polyprotein0101
Chain B, Pol Polyprotein0101
Cannabinoid receptor 10303
Microsomal triglyceride transfer protein large subunit0101
Envelope glycoprotein gp160 [Cleaved into: Surface protein gp120 0101
Fructose-1,6-bisphosphatase 1 0001
Reverse transcriptase 0112
Mitochondrial 2-oxodicarboxylate carrier0101
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))0101
Chain A, Casein kinase II subunit alpha0101
acetyl-CoA acetyltransferase/HMG-CoA reductase0101
unnamed protein product0202
heat shock 70kDa protein 1A0101
Aldehyde oxidase 10202
glyceraldehyde-3-phosphate dehydrogenase isoform 13003
dual specificity protein phosphatase 30202
eukaryotic translation initiation factor 4 gamma 1 isoform 40202
mothers against decapentaplegic homolog 3 isoform 10101
heat shock cognate 71 kDa protein isoform 10101
eukaryotic translation initiation factor 4E isoform 10202
Tat0404
dual specificity protein phosphatase 60101
heat shock cognate 71 kDa protein isoform 20101
cAMP-dependent protein kinase catalytic subunit alpha0202
Glutathione S-transferase Mu 10101
Mitogen-activated protein kinase kinase kinase 80404
Ectonucleoside triphosphate diphosphohydrolase 10101
DNA primase0404
Tyrosine-protein kinase Lyn 0101
Polypeptide N-acetylgalactosaminyltransferase 20224
ELAV-like protein 30303
Tyrosine-protein kinase Fgr0101
Glutathione S-transferase0101
Translin-associated protein X0101
DNA polymerase iota0101
DNA polymerase eta0101
Cysteine protease ATG4B0202
likely tRNA 2'-phosphotransferase0202
NS5 0011
Serine hydrolase RBBP90101
Chain A, PROTEIN KINASE CK2, ALPHA SUBUNIT0101
Chain A, Casein kinase II, alpha chain0101
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0011
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase0011
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ0101
Protein tyrosine phosphatase type IVA 30101
Accessory gene regulator protein A0101
Genome polyprotein0101
Casein kinase II subunit alpha0101
Tissue alpha-L-fucosidase0202
Sodium/glucose cotransporter 10336
Sodium/glucose cotransporter 20437
Succinyl-diaminopimelate desuccinylase0202
Opioid receptor, delta 1b 0202
Opioid receptor homologue0202
Proenkephalin-B0011
Kappa-type opioid receptor09111
Mu-type opioid receptor0202
Catechol O-methyltransferase0303
UDP-glucuronosyltransferase 2B150001
Histone deacetylase 80617
Histone deacetylase-like amidohydrolase0617
Histone deacetylase 0404
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10011
Chain A, POLYMERASE PA0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
Chain A, Polymerase Pa0101
Genome polyprotein 08211
POsterior Segregation0077
Polycomb protein EED0213
NAD kinase0213
Polymerase acidic protein0112
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0404
Alpha-amylase 1A 0404
Apoptosis regulator Bcl-209312
Glucose-6-phosphate 1-dehydrogenase0101
CPG DNA methylase0202
Phosphoglycerate mutase 10202
Signal transducer and activator of transcription 1-alpha/beta0112
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT60303
6-phosphogluconate dehydrogenase, decarboxylating0505
BH3-interacting domain death agonist0202
Bcl-2-like protein 108210
Alpha-(1,3)-fucosyltransferase 70303
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 10303
Bcl-2-related protein A10101
3-oxoacyl-[acyl-carrier-protein] reductase 0101
Histone acetyltransferase KAT2B0202
Bcl-2-like protein 20404
Bcl2-associated agonist of cell death 0303
Histone acetyltransferase KAT50101
Bcl-2-like protein 100101
Zinc finger protein mex-50077
Genome polyprotein 0202
Cathepsin S0101
[Histone H3]-lysine0101
Histone-binding protein RBBP40101
Polycomb protein SUZ120202
Histone-lysine N-methyltransferase EZH20415
Zinc finger protein AEBP20101
Histone-lysine N-methyltransferase EZH10202
M18 aspartyl aminopeptidase0303
cathepsin L10303
Serine/threonine-protein kinase B-raf 0303
Motilin receptor0011
low molecular weight phosphotyrosine protein phosphatase isoform c0202
Motilin receptor0112
Chitinase B0101
Low molecular weight phosphotyrosine protein phosphatase0505
Lanosterol 14-alpha demethylase0022
Chain A, GLUTATHIONE TRANSFERASE A1-10101
Chain A, Glutathione S-transferase P1-10101
Chain A, Glutathione S-transferase P1-10101
Chain B, Glutathione S-transferase P1-10101
Hematopoietic prostaglandin D synthase0202
Glutathione S-transferase A10101
14 kDa phosphohistidine phosphatase0303
Glutaminyl-peptide cyclotransferase0101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0303
Nuclear receptor subfamily 1 group I member 3 0202
Voltage-dependent calcium channel subunit alpha-2/delta-10303
Type IV secretion-like conjugative transfer relaxase protein TraI 0101
galanin receptor type 30202
D(3) dopamine receptor isoform e1001
Regulatory protein E20022
DNA topoisomerase 20002
Caspase-30404
DNA topoisomerase 2-alpha 0001
Amine oxidase [flavin-containing] B0303
Protein farnesyltransferase subunit beta0001
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha0001
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha0113
Protein farnesyltransferase subunit beta0113
Geranylgeranyl pyrophosphate synthase0203
Sterol regulatory element-binding protein 20101
Fatty acid-binding protein, liver0112
Peroxisome proliferator-activated receptor alpha0235
Peroxisome proliferator-activated receptor alpha0011
Retinol-binding protein 40033
Prosaposin0011
Indoleamine 2,3-dioxygenase 20606
Hyaluronidase-10202
Na(+)/H(+) exchange regulatory cofactor NHE-RF10101
Steroid 17-alpha-hydroxylase/17,20 lyase0404
Lanosterol 14-alpha demethylase0123
Cytochrome P450 11B1, mitochondrial0303
Cytochrome P450 11B2, mitochondrial0303
Malate dehydrogenase, cytoplasmic0404
Cytochrome P450 1440033
Steroid C26-monooxygenase0033
Steroid C26-monooxygenase0033
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Sterol 14-alpha demethylase0022
14-alpha sterol demethylase 0022
Skn7p0002
Chain A, Uracil Phosphoribosyltransferase0101
Acid-sensing ion channel 30101
Acid-sensing ion channel 10101
Arylacetamide deacetylase0104
Arylacetamide deacetylase0002
Arylacetamide deacetylase0002
Chain A, Dihydrofolate reductase0011
Thymidylate synthase0707
Dihydrofolate reductase07412
Folylpolyglutamate synthase, mitochondrial0104
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0205
Interleukin-20011
Menin0112
Lecithin retinol acyltransferase0101
Protein Rev 0022
Fucose-binding lectin PA-IIL0202
CD209 antigen0303
Steroid hormone receptor ERR10404
NAD-dependent protein deacylase sirtuin-5, mitochondrial0708
Methionine aminopeptidase 20404
Methionine aminopeptidase 10101
NADP-dependent malic enzyme, mitochondrial0002
Glucose-6-phosphate 1-dehydrogenase0606
Corticosteroid 11-beta-dehydrogenase isozyme 10314
Holo-[acyl-carrier-protein] synthase0101
Dopamine beta-hydroxylase 0202
Dopamine beta-hydroxylase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Protein disulfide-isomerase0202
Histone-lysine N-methyltransferase SETD70505
L-selectin0101
P-selectin0101
E-selectin0101
Anthrax toxin receptor 20404
Toll-like receptor 2 0101
Thioredoxin0101
Thioredoxin, mitochondrial0101
Gamma-aminobutyric acid receptor subunit rho-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0202
Sodium- and chloride-dependent betaine transporter0101
4-aminobutyrate aminotransferase, mitochondrial0113
Sterol O-acyltransferase 10011
Caspase 6, apoptosis-related cysteine peptidase0003
Transitional endoplasmic reticulum ATPase0101
Zinc finger protein GLI10101
Zinc finger protein GLI20101
epidermal growth factor receptor isoform a precursor1102
Serine/threonine-protein kinase ULK30033
Chain A, DEOXYNUCLEOSIDE KINASE0101
Chain A, Estrogen receptor 1 (alpha)0101
Chain A, Transthyretin0011
Chain A, Transthyretin0011
Alpha-mannosidase0101
Maltase-glucoamylase, intestinal0303
Steroid hormone receptor ERR20101
Ornithine decarboxylase0202
Solute carrier family 2, facilitated glucose transporter member 40202
Cystic fibrosis transmembrane conductance regulator0011
Alpha-glucosidase MAL320101
DNA (cytosine-5)-methyltransferase 3-like0202
DNA (cytosine-5)-methyltransferase 3A0303
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
Glutamate receptor ionotropic, kainate 11315
Glutamate receptor ionotropic, kainate 21315
Glutamate receptor ionotropic, kainate 41304
Leukotriene B4 receptor 11417
Glutamate receptor ionotropic, kainate 51304
Histone-lysine N-methyltransferase SUV39H10303
Acetolactate synthase catalytic subunit, mitochondrial0101
Geranylgeranyl transferase type-1 subunit beta0101
Mycothiol S-conjugate amidase0101
E3 ubiquitin-protein ligase RNF310101
RanBP-type and C3HC4-type zinc finger-containing protein 10101
Sharpin0101
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0112
Glucagon receptor0011
Glucagon receptor0011
Asialoglycoprotein receptor 10112
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
Metabotropic glutamate receptor 80202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Metabotropic glutamate receptor 10415
Metabotropic glutamate receptor 20112
Metabotropic glutamate receptor 30112
Metabotropic glutamate receptor 40213
Metabotropic glutamate receptor 60112
Metabotropic glutamate receptor 70112
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 80011
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80213
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Glutamate racemase0001
Chain A, Glutamine Binding Protein0011
Asc-type amino acid transporter 10202
Glutathione reductase0103
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Sodium- and chloride-dependent glycine transporter 10202
Large neutral amino acids transporter small subunit 109010
Sodium- and chloride-dependent glycine transporter 20101
High mobility group protein B10033
High mobility group protein B10001
Corticosteroid 11-beta-dehydrogenase isozyme 20112
Estrogen receptor 10202
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase1001
L-lactate dehydrogenase A chain0202
Malate dehydrogenase, mitochondrial0101
L-lactate dehydrogenase B chain0101
Malate dehydrogenase, cytoplasmic0101
L-lactate dehydrogenase B chain0101
DNA-3-methyladenine glycosylase0101
Type 1 InsP3 receptor isoform S2 1001
L-lactate dehydrogenase0101
Aspartyl/asparaginyl beta-hydroxylase0303
L-lactate dehydrogenase0101
L-lactate dehydrogenase B chain0101
L-lactate dehydrogenase0101
Inosine-5'-monophosphate dehydrogenase 0101
Histamine H3 receptor1304
estrogen receptor beta isoform 10202
Acyl-CoA desaturase 10202
4-aminobutyrate aminotransferase, mitochondrial0101
Putative nucleoside diphosphate kinase0033
Growth hormone secretagogue receptor type 10112
Eukaryotic translation initiation factor 2-alpha kinase 30101
Chain A, Bromodomain-containing protein 40011
ATPase family AAA domain-containing protein 20011
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0022
Purine nucleoside phosphorylase 0012
Chain A, Hypoxanthine Phosphoribosyltransferase0101
Chain A, HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE0101
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain B, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain A, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE0011
Chain A, Xanthine phosphoribosyltransferase0011
Histidine triad nucleotide-binding protein 10011
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
2-dehydropantoate 2-reductase0011
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0134
5-hydroxytryptamine receptor 2A0101
AP-2 complex subunit sigma0101
Calcitonin gene-related peptide type 1 receptor0101
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
STE240002
DNA repair and recombination protein RAD54-like isoform 10001
Chain A, Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
CDC-like kinase 1, isoform CRA_c0001
dual specificity protein kinase CLK41001
Dual specificity protein kinase CLK20101
Dual specificity protein kinase CLK30101
Dual specificity protein kinase CLK40101
Dual specificity tyrosine-phosphorylation-regulated kinase 30101
Sodium-dependent dopamine transporter0101
Neuromedin-B receptor0101
Mitogen-activated protein kinase 10202
Serine/threonine-protein kinase haspin0101
Dual specificity tyrosine-phosphorylation-regulated kinase 40101
Chain E, Fibrin beta chain0202
MPI protein0101
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
CDK50001
endoribonuclease toxin MazF0022
3-oxo-5-alpha-steroid 4-dehydrogenase 20202
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
transforming acidic coiled-coil-containing protein 30001
Histamine H3 receptor0202
Histamine N-methyltransferase 0101
Equilibrative nucleoside transporter 40001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Chain A, HISTIDINE-BINDING PROTEIN0011
Histidine-binding periplasmic protein0011
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10506
Cyclic GMP-AMP synthase0202
Toll-like receptor 90101
Toll-like receptor 70101
Uracil nucleotide/cysteinyl leukotriene receptor0303
Ribonucleoside-diphosphate reductase large subunit0101
Genome polyprotein0101
Small conductance calcium-activated potassium channel protein 30101
Oleandomycin glycosyltransferase0001
Dopamine beta-hydroxylase0101
Corticotropin-releasing factor receptor 10101
Cystathionine beta-synthase0202
5-lipoxygenase 0101
Thioredoxin reductase 2, mitochondrial0101
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Beta-lactamase 0001
Beta-lactamase 0003
Beta-lactamase IMP-1 0003
Beta-lactamase 0003
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Peptide deformylase 1A, chloroplastic/mitochondrial0101
Peptide deformylase 0101
Trp operon repressor0011
Chain A, membrane-associated prostaglandin E synthase-20101
Phospholipase A2, major isoenzyme0202
C-X-C chemokine receptor type 30202
Prostaglandin D2 receptor 0202
Dehydrogenase/reductase SDR family member 90101
Prostaglandin D2 receptor 20213
Chain A, ADENOSINE DEAMINASE0101
Chain A, ADENOSINE DEAMINASE0101
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Sodium/myo-inositol cotransporter 20101
Peptidylglycine alpha-amidating monooxygenase0001
Chain A, Acetylcholinesterase0101
Dihydroorotate dehydrogenase (quinone), mitochondrial08210
Neuronal acetylcholine receptor subunit beta-209312
Neuronal acetylcholine receptor subunit alpha-705510
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a0011
3-oxoacyl-[acyl-carrier-protein] synthase 3 0202
N-glycosylase/DNA lyase0101
Formamidopyrimidine-DNA glycosylase0101
Endonuclease III-like protein 10101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
Chain A, beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Chain A, Beta-galactosidase0101
Beta-galactosidase0101
Beta-2 adrenergic receptor0011
Beta-3 adrenergic receptor0011
Beta-1 adrenergic receptor0314
Beta-2 adrenergic receptor0202
Taste receptor type 2 member 380023
Taste receptor type 2 member 390011
Taste receptor type 2 member 400011
Taste receptor type 2 member 410011
Taste receptor type 2 member 430011
Taste receptor type 2 member 310134
Taste receptor type 2 member 450011
Taste receptor type 2 member 460011
Taste receptor type 2 member 300011
Taste receptor type 2 member 190011
Taste receptor type 2 member 200011
Taste receptor type 2 member 500011
Taste receptor type 2 member 600022
Beta-2 adrenergic receptor 0112
Taste receptor type 2 member 420011
Taste receptor type 2 member 160011
Taste receptor type 2 member 140023
Taste receptor type 2 member 130022
Taste receptor type 2 member 100011
Taste receptor type 2 member 90022
Taste receptor type 2 member 80011
Taste receptor type 2 member 70011
Taste receptor type 2 member 50011
Taste receptor type 2 member 40022
Taste receptor type 2 member 30011
Taste receptor type 2 member 10011
Protein E60303
Beta-glucuronidase0101
E3 ubiquitin-protein ligase XIAP0437
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Camphor 5-monooxygenase0001
Epoxide hydrolase 10001
Cytochrome P450 2C11 0202
Steroid 21-hydroxylase0101
Steroid 17-alpha-hydroxylase/17,20 lyase 0202
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0303
Cytochrome P450 7A1 0101
Gonadotropin-releasing hormone receptor0314
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Caspase-40303
Caspase-50303
Caspase-90303
Cell division control protein 42 homolog0101
Ras-related C3 botulinum toxin substrate 10123
Cysteinyl leukotriene receptor 20202
Splicing factor 3B subunit 30303
Capsid protein 0123
phosphoethanolamine/phosphocholine phosphatase isoform 10101
WD repeat-containing protein 50404
Histone-lysine N-methyltransferase 2A0404
Cytosolic endo-beta-N-acetylglucosaminidase0303
Dihydroorotate dehydrogenase 0303
Chain A, Epidermal growth factor receptor0101
Alpha-1A adrenergic receptor 0101
Baculoviral IAP repeat-containing protein 20224
Baculoviral IAP repeat-containing protein 30112
Baculoviral IAP repeat-containing protein 70101
DNA-binding protein Ikaros0014
DNA damage-binding protein 10213
Zinc finger protein Aiolos0011
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0707
Intestinal-type alkaline phosphatase0505
Phospholipase A-2-activating protein0505
Gonadotropin-releasing hormone receptor0101
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0303
Intestinal-type alkaline phosphatase0202
5'-nucleotidase0303
Synaptic vesicle glycoprotein 2A0101
CAAX prenyl protease 2 isoform 20001
Isocitrate dehydrogenase [NADP] cytoplasmic0112
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 2 subunit alpha0404
Sodium channel protein type 3 subunit alpha0303
Potassium voltage-gated channel subfamily A member 50303
Potassium voltage-gated channel subfamily D member 20202
Potassium channel subfamily K member 180101
Sterol O-acyltransferase 10202
Fatty acid-binding protein, heart0202
Sterol O-acyltransferase 10303
Dual specificity protein phosphatase 30202
N-formyl peptide receptor 20123
inositol monophosphatase 12002
Ephrin type-A receptor 20101
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
Nociceptin receptor0101
Chain A, protease0101
Chain B, protease0101
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, PROTEASE RETROPEPSIN0101
Chain B, PROTEASE RETROPEPSIN0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
CAAX prenyl protease 1 homolog0101
Plasmepsin V 0202
Neprilysin0101
Type-1 angiotensin II receptor0213
Chain A, Antigen Cd11a (p180)0101
Integrin beta-20101
Intercellular adhesion molecule 10101
Integrin alpha-L0213
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
Queuine tRNA-ribosyltransferase0101
histidine kinase 0101
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 70003
Chemotaxis protein CheA0101
Cytosol aminopeptidase0202
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 10404
Macrophage metalloelastase0303
Protein polybromo-10011
DNA topoisomerase 10101
TGF-beta receptor type-10101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Thymidine phosphorylase0102
Alpha-mannosidase 2C10202
C-C chemokine receptor type 50101
C-C chemokine receptor type 50101
Chain A, A disintegrin and metalloproteinase with thrombospondin motifs 50101
Chain A, Catalytic Domain of ADAMTS-50101
Chain A, A disintegrin and metalloproteinase with thrombospondin motifs 50101
Zinc metalloproteinase dpy-310101
Zinc metalloproteinase dpy-310101
ADAM100101
disintegrin and metalloproteinase domain-containing protein 17 isoform 1 preproprotein0101
Matrix metalloproteinase-200101
A disintegrin and metalloproteinase with thrombospondin motifs 40101
Tumor necrosis factor0213
Stromelysin-20101
Matrix metalloproteinase-150101
Matrix metalloproteinase-160101
Matrix metalloproteinase-250101
Matrix metalloproteinase-260101
A disintegrin and metalloproteinase with thrombospondin motifs 50101
Matrix metalloproteinase-240101
bioA0001
Cytochrome P450 1A2 0115
Nociceptin receptor0101
Melatonin receptor type 1C0011
Melatonin receptor type 1A0213
Melatonin receptor type 1C0213
Melatonin receptor type 1B0213
Large neutral amino acids transporter small subunit 1 0202
Secreted chorismate mutase0202
Neuraminidase0101
Cystathionine gamma-lyase0303
Cystine/glutamate transporter0202
Hydroxyacid oxidase 10101
Aldehyde oxidase 1 0202
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Thymidylate synthase 0303
Thymidylate synthase 0202
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30103
Dihydrofolate reductase0607
Dihydrofolate reductase0101
Dihydrofolate reductase0405
Thymidylate synthase0405
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Folate receptor beta0303
Folate receptor alpha0303
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30303
Bifunctional purine biosynthesis protein ATIC0505
Reduced folate transporter0404
Bifunctional dihydrofolate reductase-thymidylate synthase0505
Bifunctional dihydrofolate reductase-thymidylate synthase0303
Trifunctional purine biosynthetic protein adenosine-30202
Dihydrofolate reductase 0101
Dihydrofolate reductase0505
Proton-coupled folate transporter0405
SUMO-1-specific protease0101
SUMO1/sentrin specific peptidase 70101
histone-lysine N-methyltransferase NSD2 isoform 10002
caspase-3 isoform a preproprotein0202
sentrin-specific protease 80101
T cell receptor, partial1001
luteinizing hormone receptor1001
Apoptotic peptidase activating factor 10101
caspase-9 isoform alpha precursor0101
Dihydrolipoyl dehydrogenase, mitochondrial0104
Dihydrolipoyl dehydrogenase 0102
Serine racemase0101
5-hydroxytryptamine receptor 3B0505
Thioredoxin reductase 0101
Flavodoxin0001
G-protein coupled receptor 0101
Chain A, PROGESTERONE RECEPTOR0101
Glucocorticoid receptor 0101
Tegument protein VP160011
Glucocorticoid receptor0112
Progesterone receptor0011
Glucocorticoid receptor0101
Multidrug transporter MdfA0202
S-adenosylmethionine decarboxylase proenzyme0102
S-adenosylmethionine decarboxylase proenzyme0101
Chain A, Probable serine/threonine-protein kinase pknB0101
phospholipase A2, group III0101
NEDD8-activating enzyme E1 regulatory subunit0123
NEDD8-activating enzyme E1 catalytic subunit0123
Aurora kinase A0303
Inner centromere protein0101
Targeting protein for Xklp20101
Nuclear receptor corepressor 10303
Chain A, HEAT SHOCK PROTEIN 900011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 10101
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30101
Chain A, Atp-dependent Molecular Chaperone Hsp820011
Chain A, Atp-dependent Molecular Chaperone Hsp820011
Chain B, Type 2 DNA topoisomerase 6 subunit B0011
Chain A, Virulence sensor histidine kinase phoQ0011
ATP-dependent molecular chaperone HSP820213
Virulence sensor histidine kinase PhoQ0011
ATP-dependent molecular chaperone HSC820202
Proto-oncogene tyrosine-protein kinase Src 0101
Histidine kinase 0101
Nociceptin receptor0101
Mu-type opioid receptor0101
Phosphotyrosine protein phosphatase 0202
Low molecular weight protein-tyrosine phosphatase A0101
Tyrosine-protein phosphatase non-receptor type 120101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Tyrosine-protein phosphatase non-receptor type 220101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A80002
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-10101
Chain A, Pancreatic alpha-amylase0101
Chain A, Pancreatic alpha-amylase0101
serine/threonine-protein kinase 33 isoform a0033
DNA dC->dU-editing enzyme APOBEC-3A isoform a0101
Tyrosine-protein kinase transforming protein Fps0101
Solute carrier family 2, facilitated glucose transporter member 20202
Solute carrier family 2, facilitated glucose transporter member 4 0202
DNA primase TraC0101
2-5A-dependent ribonuclease0102
Aldo-keto reductase family 1 member C210303
Carboxypeptidase B20202
Prostaglandin E synthase0101
Presenilin-10101
Presenilin-20101
Gamma-secretase subunit APH-1B0101
Nicastrin0101
Gamma-secretase subunit APH-1A0101
Sialidase-40101
Sialidase-10101
Sialidase-30101
Formyl peptide receptor-related sequence 10011
fMet-Leu-Phe receptor0224
FML2_HUMAN 0011
vasopressin V1b receptor1001
relaxin receptor 2 isoform 11001
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
ubiquitin-like modifier-activating enzyme 10101
ubiquitin-conjugating enzyme E2 variant 1 isoform a0101
Complement C1r subcomponent0101
Complement C1s subcomponent0101
Hepatocyte growth factor activator0213
Suppressor of tumorigenicity 14 protein0101
Chain A, Cholix toxin0101
Beta-hexosaminidase subunit alpha0203
Hormone-sensitive lipase0101
G protein-activated inward rectifier potassium channel 20011
G protein-activated inward rectifier potassium channel 40011
G protein-activated inward rectifier potassium channel 10011
Bcl-2-like protein 110101
Neuropeptide Y receptor type 10202
Neuropeptide Y receptor type 20202
Cholesteryl ester transfer protein0314
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
Hydroxycarboxylic acid receptor 20112
Chain A, NAD-dependent deacetylase0101
NAD-dependent protein deacetylase HST20303
NAD(+) hydrolase SARM10202
NAD-dependent protein deacetylase sirtuin-60314
NAD-dependent protein deacetylase 0101
Equilibrative nucleoside transporter 10101
Anoctamin-10101
Neuronal acetylcholine receptor subunit alpha-40213
Acetylcholine receptor subunit alpha0527
Acetylcholine receptor subunit alpha0213
Acetylcholine receptor subunit beta0213
Acetylcholine receptor subunit gamma0213
Acetylcholine receptor subunit delta0213
Acetylcholine receptor subunit gamma0527
Neuronal acetylcholine receptor subunit alpha-40101
Acetylcholine receptor subunit beta0527
Acetylcholine receptor subunit beta-like 20202
Neuronal acetylcholine receptor subunit alpha-50022
Neuronal acetylcholine receptor subunit beta-40639
Neuronal acetylcholine receptor subunit alpha-307310
Neuronal acetylcholine receptor subunit alpha-408311
Neuronal acetylcholine receptor subunit alpha-70404
Acetylcholine-binding protein0112
Neuronal acetylcholine receptor subunit beta-30112
Acetylcholine receptor subunit delta0527
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit alpha-60112
Cytochrome P450 2A130224
Neuronal acetylcholine receptor subunit alpha-50202
Liver carboxylesterase B-10101
Neuronal acetylcholine receptor subunit beta-30202
Neuronal acetylcholine receptor subunit beta-40202
Neuronal acetylcholine receptor subunit alpha-30202
Soluble acetylcholine receptor0101
Neuronal acetylcholine receptor subunit alpha-20202
Neuronal acetylcholine receptor subunit beta-20213
Neuronal acetylcholine receptor subunit alpha-60202
Integrin beta0011
Glycoprotein IIb0011
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium channel subfamily K member 2 0101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Platelet-derived growth factor receptor beta0606
Platelet-derived growth factor receptor alpha 0404
Vascular endothelial growth factor receptor 20404
Protein mono-ADP-ribosyltransferase PARP140224
Protein mono-ADP-ribosyltransferase PARP100336
Protein mono-ADP-ribosyltransferase PARP160134
Protein mono-ADP-ribosyltransferase PARP120325
Protein mono-ADP-ribosyltransferase PARP110022
Protein mono-ADP-ribosyltransferase PARP40336
Protein mono-ADP-ribosyltransferase PARP303510
Sodium/iodide cotransporter0101
G-protein coupled receptor 550101
Chain A, Glutathione-requiring prostaglandin D synthase0101
Signal transducer and activator of transcription 10101
Signal transducer and activator of transcription 3 0101
Protein Mdm40202
E3 ubiquitin-protein ligase Mdm20101
E3 ubiquitin-protein ligase Mdm20101
Peptidyl-prolyl cis-trans isomerase D0101
Mu-type opioid receptor0011
Methylated-DNA--protein-cysteine methyltransferase0102
DNA polymerase lambda0101
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase0101
Solute carrier family 22 member 190001
Protein mono-ADP-ribosyltransferase PARP60101
Protein mono-ADP-ribosyltransferase PARP80022
Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain]0011
Receptor-type tyrosine-protein phosphatase C0101
Receptor-type tyrosine-protein phosphatase F0303
Receptor-type tyrosine-protein phosphatase alpha0202
Chain A, Adipocyte Lipid-binding Protein0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
Chain A, MUSCLE FATTY ACID BINDING PROTEIN0011
putative potassium channel subunit0011
Peroxisome proliferator-activated receptor delta0539
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
Nitric oxide synthase, brain0101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
Bombesin receptor subtype-30011
Interleukin-6 receptor subunit alpha0101
Thyrotropin-releasing hormone receptor0101
Glycine receptor subunit alpha-40101
Leukotriene B4 receptor 10101
Chain A, ARGINASE 10101
Chain A, Arginase 10101
Chain A, ARGINASE 10101
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE0101
Solute carrier family 2, facilitated glucose transporter member 90224
Chain H, Igg2b-kappa 40-50 Fab (heavy Chain)0101
Chain L, Igg2b-kappa 40-50 Fab (light Chain)0101
Chain A, Na, K-ATPase alpha subunit0011
Kruppel-like factor 50101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-30101
Microphthalmia-associated transcription factor0001
caspase recruitment domain family, member 150101
receptor-interacting serine/threonine-protein kinase 2 isoform 10101
Chain A, Bacterial leucyl aminopeptidase0101
Thermolysin0203
Methionine aminopeptidase 10101
Oxytocin receptor0011
Ubiquitin carboxyl-terminal hydrolase 470202
Beta-tubulin 0101
Chain B, Cell division protein kinase 60101
Chain B, Cell division protein kinase 60101
Chain A, Fatty acid-binding protein, adipocyte0101
Toll-like receptor 20101
Protein Tat0022
NAD-dependent protein deacetylase sirtuin-70202
Pyrroline-5-carboxylate reductase 1, mitochondrial0101
Renin0101
Beta-adrenergic receptor kinase 10202
Rhodopsin kinase GRK10101
G protein-coupled receptor kinase 50202
G protein-coupled receptor kinase 50101
P2X purinoceptor 40123
Envelope glycoprotein0011
P2X purinoceptor 40101
Beta-adrenergic receptor kinase 10001
BZLF20101
Testosterone 17-beta-dehydrogenase 30101
Nuclear receptor subfamily 4 group A member 30101
Peroxiredoxin-like 2A0101
Tyrosine-protein kinase transforming protein Abl0101
Fructose-1,6-bisphosphatase 10101
Protein kinase C alpha type0202
Fructose-1,6-bisphosphatase 1 0101
Chain A, Protein (fibroblast Growth Factor (fgf) Receptor 1)0101
Luciferin 4-monooxygenase0213
Dual specificity mitogen-activated protein kinase kinase 2 0101
Dual specificity mitogen-activated protein kinase kinase 1 0101
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Serine hydroxymethyltransferase, cytosolic0112
Thymidylate synthase 0202
Beta-lactamase 10001
Beta-lactamase OXA-100001
Chain C, Respiratory nitrate reductase 1 gamma chain0101
Pentachlorophenol 4-monooxygenase0011
Ubiquitin-like modifier-activating enzyme 60101
Ubiquitin-like modifier-activating enzyme ATG70101
Ubiquitin-like modifier-activating enzyme 1 0101
NEDD80101
SUMO-activating enzyme subunit 10101
SUMO-activating enzyme subunit 20101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Lysosomal Pro-X carboxypeptidase0101
Muscarinic acetylcholine receptor M50012
Olfactory receptor class A-like protein 10011
SLC16A10 protein0003
Monocarboxylate transporter 100003
fMet-Leu-Phe receptor0101
Alpha-1B adrenergic receptor0101
Sodium/glucose cotransporter 1 0101
Sodium/glucose cotransporter 20101
Solute carrier family 5 member 40101
Proto-oncogene vav0011
Protein kinase C delta type0112
Transient receptor potential cation channel subfamily V member 4 0011
Chain A, phosphoenolpyruvate carboxykinase, cytosolic0101
Chain A, Phosphoenolpyruvate Carboxykinase, Cytosolic0101
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]0101
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
CDGSH iron-sulfur domain-containing protein 10202
Peroxisome proliferator-activated receptor gamma0101
Carnitine O-palmitoyltransferase 2, mitochondrial0202
CDGSH iron-sulfur domain-containing protein 20202
Peroxisomal sarcosine oxidase0001
Transforming growth factor beta-1 proprotein0202
Mothers against decapentaplegic homolog 3 0202
C-X-C chemokine receptor type 40101
Atypical chemokine receptor 30011
C-X-C chemokine receptor type 40204
Mitogen-activated protein kinase kinase kinase 140101
Chain A, AKAP9-BRAF fusion protein0101
Pirin0101
Dual specificity mitogen-activated protein kinase kinase 40011
Regulatory protein E20011
Regulatory protein E20011
Calcium-activated potassium channel subunit alpha-10101
Sodium/potassium/calcium exchanger 40112
Sodium/potassium/calcium exchanger 20112
luciferase0001
Glutamine synthetase0011
Nociceptin receptor0011
Voltage-dependent calcium channel subunit alpha-2/delta-10102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Histamine H2 receptor0101
Glutamate 5-kinase0001
Free fatty acid receptor 20011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Neuromedin-K receptor0011
Nuclear receptor subfamily 2 group E member 10022
NADH-cytochrome b5 reductase 3 0101
Thyroid peroxidase0101
tyrosine-protein phosphatase non-receptor type 7 isoform 20202
Chain A, Protocatechuate 3,4-dioxygenase alpha chain0011
Chain B, Protocatechuate 3,4-dioxygenase beta chain0011
SUMO-10101
chaperonin GroEL1001
Exoribonuclease H 0101
Coproheme decarboxylase0011
Interleukin-50101
Interleukin-50101
Interleukin-5 receptor subunit alpha0101
Chain A, PUTRESCINE-BINDING PROTEIN0011
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN0101
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN0101
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN0101
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0404
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0404
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
Chain A, Mitogen-activated protein kinase 100101
polyadenylate-binding protein 10202
Serine/threonine-protein kinase 30022
P2X purinoceptor 10022
P2X purinoceptor 10101
Trans-sialidase0101
Trans-sialidase0101
P2X purinoceptor 20011
tyrosine-protein phosphatase non-receptor type 22 isoform 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Beta-hexosaminidase subunit beta0101
Substance-K receptor0213
Dihydrofolate reductase0303
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Trace amine-associated receptor 50011
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Multidrug and toxin extrusion protein 10101
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Monocarboxylate transporter 20002
C-terminal-binding protein 20101
Monocarboxylate transporter 20202
Chain A, APH(2')-Id0101
glucose-6-phosphate dehydrogenase0101
hexokinase0101
Chymotrypsin-like elastase family member 10202
Epoxide hydrolase 1 0101
Malate dehydrogenase0202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10202
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
ELAV-like protein 10101
Probable maltase-glucoamylase 20101
N0101
DNA-directed RNA polymerase subunit alpha0101
DNA-directed RNA polymerase subunit omega0101
DNA-directed RNA polymerase subunit beta'0101
DNA-directed RNA polymerase subunit beta0101
Phospholipase A2, membrane associated0101
Acidic phospholipase A2 20101
Multidrug resistance protein 1a0001
Liver carboxylesterase 10101
Prolyl 4-hydroxylase, beta polypeptide0001
Gastric inhibitory polypeptide receptor0101
Chain A, Thymidylate Synthase0101
Chain B, Thymidylate Synthase0101
Chain A, THYMIDYLATE SYNTHASE0101
Chain A, THYMIDYLATE SYNTHASE0101
Vascular endothelial growth factor receptor 30202
Chromaffin granule amine transporter0101
Synaptic vesicular amine transporter0213
Synaptic vesicular amine transporter0101
Chain A, Bacterial regulatory proteins, tetR family0011
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Troponin C, slow skeletal and cardiac muscles0011
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Chain A, Leukotriene A-4 hydrolase0101
Aryl hydrocarbon receptor0101
Myc proto-oncogene protein0102
DNA polymerase alpha catalytic subunit0101
N1L 0101
Lysosomal alpha-glucosidase0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Beta-lactoglobulin0011
DNA (cytosine-5)-methyltransferase 3B0202
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
DNA-directed RNA polymerase subunit beta0101
NH(3)-dependent NAD(+) synthetase0101
DNA-directed RNA polymerase subunit beta0101
Butyrophilin subfamily 3 member A10023
4-hydroxy-3-methylbut-2-enyl diphosphate reductase0101
Farnesyl diphosphate synthase0101
H0202
Phosphotransferase 0101
Farnesyl diphosphate synthase0101
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
Prostaglandin G/H synthase 20101
Cytochrome c oxidase subunit 10101
Transporter0101
Sodium-dependent serotonin transporter0101
ATP-binding cassette sub-family C member 80202
ATP-sensitive inward rectifier potassium channel 110202
Thrombin 0011
Transcription factor AP-10101
UDP-galactopyranose mutase0011
UDP-galactopyranose mutase0011
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial0101
Dihydroorotate dehydrogenase (fumarate)0101
Acyl carrier protein, mitochondrial0101
Dihydroorotate dehydrogenase 0303
GDH/6PGL endoplasmic bifunctional protein0101
Protein mono-ADP-ribosyltransferase PARP90011
Neuromedin-U receptor 20022
Low-density lipoprotein receptor0101
Fibronectin0101
Macrophage colony-stimulating factor 1 receptor0101
Proprotein convertase subtilisin/kexin type 90101
Chain A, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI0011
Chain A, Adenine-n6-dna-methyltransferase Taqi0011
Chain A, Histamine N-Methyltransferase0101
Chain A, Histamine N-Methyltransferase0101
Chain A, Modification Methylase Rsri0011
Chain A, Modification Methylase Rsri0011
Chain A, Ermc' Methyltransferase0101
Chain A, Ermc' Rrna Methyltransferase0101
Chain A, Uroporphyrin-III C-methyltransferase0101
Chain B, ADENINE-N6-DNA-METHYLTRANSFERASE TAQI0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase0011
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase0011
tRNA (cytosine(38)-C(5))-methyltransferase0112
Protein arginine N-methyltransferase 50101
Adenosylhomocysteinase0001
Protein arginine N-methyltransferase 30101
Indolethylamine N-methyltransferase0101
Histone-lysine N-methyltransferase NSD20101
Adenosylhomocysteinase0001
rRNA adenine N-6-methyltransferase0101
tRNA (guanine-N(1)-)-methyltransferase0011
Histone-lysine N-methyltransferase SETDB10101
Retinoblastoma-binding protein 50101
tRNA (guanine-N(1)-)-methyltransferase0011
N6-adenosine-methyltransferase catalytic subunit0101
Histone-arginine methyltransferase CARM10101
Histone-lysine N-methyltransferase KMT5C0101
Protein arginine N-methyltransferase 10404
Methylosome protein 500101
Protein dpy-30 homolog0101
Histamine N-methyltransferase0001
Histone-lysine N-methyltransferase SUV39H20101
tRNA (guanine-N(1)-)-methyltransferase0011
Protein arginine N-methyltransferase 70101
Set1/Ash2 histone methyltransferase complex subunit ASH20101
RmtA0202
Sphingosine kinase 10202
Tyrosine-protein phosphatase YopH0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Chain A, Proto-oncogene tyrosine-protein kinase Src0101
Chain A, Erk20101
Mitogen-activated protein kinase 20101
Mitogen-activated protein kinase 14 0112
P2X purinoceptor 70101
P2X purinoceptor 70112
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET0101
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET0101
Chain A, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET0101
vasopressin V1a receptor0011
oxytocin receptor0011
Vascular endothelial growth factor receptor 10101
Vascular endothelial growth factor receptor 20202
1,25-dihydroxyvitamin D-3 receptor 0101
Programmed cell death protein 10101
Programmed cell death 1 ligand 10101
Chain A, Shikimate kinase0011
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase0101
Sterol O-acyltransferase 20101
Pyruvate kinase PKLR0101
Neuraminidase0101
Cholecystokinin receptor type A0101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Programmed cell death protein 40011
Kallikrein-10101
Chymotrypsin-like elastase family member 2A0101
Myeloblastin0101
Neutrophil elastase0101
Corticotropin releasing hormone receptor 20202
Sodium/bile acid cotransporter0104
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Chain A, Mitogen-activated protein kinase 140011
Cyclin-C0112
Protein delta homolog 10224
RuvB-like 20112
RuvB-like 10101
Protein kinase C beta type 0101
Sulfate anion transporter 10001
C-X-C chemokine receptor type 5 isoform 10101
C-C chemokine receptor type 60101
Endoglycoceramidase II 0001
cAMP-dependent protein kinase catalytic subunit alpha 0101
Sphingosine kinase 20101
Sphingosine 1-phosphate receptor 20112
Sphingosine 1-phosphate receptor 40112
Sphingosine 1-phosphate receptor 10112
Sphingosine 1-phosphate receptor 30112
Sphingosine 1-phosphate receptor 50112
Chain A, Mineralocorticoid receptor0101
Chain A, Mineralocorticoid receptor0101
Thioredoxin glutathione reductase 0101
Chain A, Ribosomal protein S6 kinase alpha-10101
Chain X, Tyrosine-protein kinase Lyn0101
Chain A, Dual specificity protein kinase TTK0011
Chain A, Dual specificity protein kinase TTK0011
Mast/stem cell growth factor receptor Kit0101
Bromodomain-containing protein 90011
Bromodomain-containing protein 70011
Substance-P receptor0202
Neuromedin-K receptor0011
Substance-K receptor0101
Substance-K receptor0101
Chain A, Protein (aspartate Aminotransferase)0011
Chain A, Aspartate Aminotransferase0011
Delta-aminolevulinic acid dehydratase0101
Solute carrier family 13 member 30101
Chain A, Glutathione S-transferase0101
Fibroblast growth factor 10011
Transcription regulator protein BACH10101
Transcription factor MafK 0101
Kelch-like ECH-associated protein 10123
Nuclear factor erythroid 2-related factor 20001
Kelch-like ECH-associated protein 10001
Complement C50011
ATP-dependent 6-phosphofructokinase0101
Ectonucleoside triphosphate diphosphohydrolase 20101
P2Y purinoceptor 10011
P2X purinoceptor 20112
P2X purinoceptor 50011
P2X purinoceptor 60011
P2Y purinoceptor 40011
P2X purinoceptor 30011
Ectonucleoside triphosphate diphosphohydrolase 10101
P2Y purinoceptor 60101
Dual specificity protein phosphatase 50101
Ectonucleoside triphosphate diphosphohydrolase 80101
Ectonucleoside triphosphate diphosphohydrolase 3 0101
P2Y purinoceptor 110112
Orexin receptor type 10202
Orexin receptor type 20202
Orexin receptor type 10101
Orexin receptor type 20101
Chain A, Alpha-mannosidase Ii0101
Chain A, ALPHA-MANNOSIDASE II0101
Chain A, Alpha-mannosidase Ii0101
Lysosomal alpha-mannosidase0101
Mannosyl-oligosaccharide alpha-1,2-mannosidase IA0202
Alpha-mannosidase 20101
Alpha-1,2-mannosidase family protein0101
Putative alpha-1,2-mannosidase0101
Alpha-1,2-mannosidase, putative0101
Putative alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Glycoside hydrolase family 920101
Glycoside hydrolase family 920101
Alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Alpha-1,2-mannosidase, putative0101
Putative alpha-1,2-mannosidase0101
Alpha-1,2-mannosidase0101
Alpha-1,2-mannosidase, putative0101
Putative alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Putative alpha-1,2-mannosidase0101
Alpha-1,2-mannosidase family protein0101
alpha-1,2-Mannosidase 0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0202
Chain A, FOCAL ADHESION KINASE 10101
Chain A, FOCAL ADHESION KINASE 10101
Chain A, FOCAL ADHESION KINASE 10101
Chain A, FOCAL ADHESION KINASE 10101
Chain A, CES1 protein0101
Lysosomal acid glucosylceramidase0011
Transcriptional activator protein LuxR0101
Phospholipase D1 0101
Phospholipase D10101
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Heat-shock protein0101
Putative heat shock protein HSP 90-alpha A40101
Chain A, Prostatic Acid Phosphatase0101
Bile salt export pump0002
Sodium/bile acid cotransporter0001
Ileal sodium/bile acid cotransporter0001
Ileal sodium/bile acid cotransporter0001
Solute carrier organic anion transporter family member0001
Solute carrier organic anion transporter family member 4A10002
Solute carrier organic anion transporter family member 1C10202
Peroxisome proliferator-activated receptor delta0011
Adenylate kinase isoenzyme 10001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Stromal interaction molecule 10101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
cGMP-gated cation channel alpha-10011
Tetracycline resistance protein, class B0001
Ras guanyl-releasing protein 30011
Alpha-enolase0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0101
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Adenosine receptor A10303
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
Cathepsin D 0101
Urease subunit alpha0101
Urease subunit beta 0101
Thymidine kinase, cytosolic 0003
Thymidine kinase 0204
Thymidine kinase0103
Chain A, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN0011
Chain A, ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN0011
Chain A, Deoxynucleoside kinase0101
Thymidine phosphorylase0101
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
Proliferating cell nuclear antigen0202
Malate dehydrogenase, mitochondrial0101
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Trace amine-associated receptor 10101
Puromycin-sensitive aminopeptidase0202
MSH0001
Transient receptor potential cation channel subfamily V member 20101
Chain A, Nuclear Receptor ROR-beta0101
Nuclear receptor ROR-alpha0101
Nuclear receptor ROR-beta0101
procathepsin L isoform 1 preproprotein0101
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)0101
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)0101
Chain A, Histone deacetylase 7a0101
Chain A, Histone deacetylase 7a0101
Histone deacetylase 0202
unnamed protein product0001
Histone deacetylase 10505
Histone deacetylase 30101
Histone deacetylase 20101
Histone deacetylase 10202
Adenosine receptor A10101
Histone deacetylase 0202
Histone deacetylase 40101
Polyamine deacetylase HDAC100101
Histone deacetylase 30202
Histone deacetylase 70101
Histone deacetylase 80101
Histone deacetylase 110101
HD2 type histone deacetylase HDA106 0404
Histone deacetylase 90101
Histone deacetylase 70202
Histone deacetylase 6 0202
Histone deacetylase 40202
Histone deacetylase 60314
Histone deacetylase 50101
Histone deacetylase 0202
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, enoyl-acyl carrier reductase0101
Chain C, enoyl-acyl carrier reductase0101
Chain A, Repressor0011
twin arginine protein translocation system - TatA protein0002
Endoplasmic reticulum chaperone BiP0101
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI0101
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI0202
Enoyl-acyl carrier reductase0101
Enoyl-ACP reductase II 0101
Delta0101
Cycloeucalenol cycloisomerase0101
Sterol-8,7-isomerase0101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Proteinase-activated receptor 20101
Forkhead box protein M10202
Chain A, CARBONIC ANHYDRASE II0101
5-hydroxytryptamine receptor 4 0001
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Polyamine deacetylase HDAC100101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Chain A, Bacterial leucyl aminopeptidase0101
Aminopeptidase B0202
M1 family aminopeptidase0202
Cytosol aminopeptidase0202
Aminopeptidase N 0101
Interleukin-1 receptor antagonist protein0101
Cytosol aminopeptidase0202
Aminopeptidase N0202
Leucyl-cystinyl aminopeptidase0101
Bacterial leucyl aminopeptidase0202
Endoplasmic reticulum aminopeptidase 20101
Aminopeptidase B0101
Endoplasmic reticulum aminopeptidase 10101
Cadherin-10101
Adenomatous polyposis coli protein0101
Catenin beta-10202
Transcription factor 7-like 20101
Hemagglutinin0022
Chain A, Uracil-DNA Glycosylase0101
Chain A, Cytidine Deaminase0101
Uridine-cytidine kinase 1 0001
Basic phospholipase A2 10101
Basic phospholipase A2 PLA-A0101
Acidic phospholipase A2 EC-I0101
Sentrin-specific protease 10101
Chain A, Carbonic anhydrase II0101
Chain A, Arginase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
D-alanyl-D-alanine dipeptidase0101
Transcription intermediary factor 1-alpha0101
Succinate-semialdehyde dehydrogenase, mitochondrial0101
E3 ubiquitin-protein ligase TRIM330101
Glycoprotein0101
Muscarinic acetylcholine receptor M20011
Chloroquine resistance transporter0101
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD70101
Aldehyde oxidase 10101
M-phase inducer phosphatase 30101
Aldehyde oxidase 10101
Ubiquitin carboxyl-terminal hydrolase isozyme L30101
Ubiquitin carboxyl-terminal hydrolase isozyme L10101
Sterol 14-alpha-demethylase0011
14-alpha sterol demethylase 0011
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
14-alpha sterol demethylase 0011
Chain A, Histone deacetylase-like amidohydrolase0101
Chain A, Histone deacetylase-like amidohydrolase0101
Gli10101
protein Wnt-3a precursor0101
Leukotriene A-4 hydrolase0101
Apoptosis regulator BAX 0011
Renin0101
Histone deacetylase 0101
REST corepressor 30101
Putative alpha-1-antitrypsin-related protein0101
Receptor-interacting serine/threonine-protein kinase 1 0101
Aurora kinase B-A0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor, alpha form0101
Chain B, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, Rho-associated protein kinase 10101
cAMP-dependent protein kinase catalytic subunit alpha 0101
C-C motif chemokine 20101
Rho-associated protein kinase 20101
Kinesin-1 heavy chain0101
Coiled-coil domain-containing protein 60101
PTK2B protein tyrosine kinase 2 beta0101
Ectonucleoside triphosphate diphosphohydrolase 10001
Tumor necrosis factor ligand superfamily member 110101
Farnesyl diphosphate synthase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]