Anal Cancer

Synonym
Neoplasms, Anus
Anal Neoplasms
Anal Cancer
Neoplasms, Anal
Cancer of Anus
Cancer of the Anus

Excerpt	Reference
"Mitomycin's role in anal cancer is being evaluated in a randomized clinical trial by the Radiation Therapy Oncology Group."	( Catton, CN; Cummings, BJ; Keane, TJ; O'Sullivan, B; Wong, CS, 1993)
"Epidermoid cancer of the anus is a rare entity which represents 1-2% of all gastrointestinal tract cancers."	( Prieto Reyes, M; Vázquez Márquez, L, 1997)
"The incidence of anal cancer is increased in men with a history of anal receptive intercourse."	( Berry, JM; Darragh, TM; Hogeboom, CJ; Holly, EA; Jay, N; Palefsky, JM, 1997)
"Metastatic anal cancer is a rare disease in the Western hemisphere and current treatment modalities are not effective."	( Catalano, PJ; Hahn, RG; Haller, D; Harris, J; Jhawer, M; Lefkopoulou, M; Mani, S, 2006)
"Anal cancer is the first tumour in which chemoradiotherapy with the intent of organ preservation has largely replaced surgery and is an interesting model of modern multimodal oncological treatment."	( Arponen, P; Blomqvist, C; Saarilahti, K; Tenhunen, M; Vaalavirta, L, 2006)
"Anal cancer is a relatively rare neoplasm, accounting for roughly 4,500 cases per year."	( Herman, J; Johnstone, PA; Konski, AA; Mohiuddin, M; Poggi, MM; Saltz, L; Suh, WW, 2007)
"Anal cancer is FDG-PET avid."	( Chao, M; Feigen, M; Joon, DL; Joon, ML; Kai, C; Khoo, V; Nguyen, BT; Quong, G; Rykers, K; Scott, A; See, A; Wada, M; Zupan, E, 2008)
"Human anal cancers are associated with high-risk human papillomaviruses (HPV) that cause other anogenital cancers and head and neck cancers."	( Lambert, PF; Liem, A; Mahoney, C; Pitot, HC; Schweizer, J; Stelzer, MK, 2010)
"The incidence of anal cancer is increasing especially among HIV-infected persons in the HAART era."	( Kennedy, GD; Lambert, PF; Lee, D; Liem, A; Pitot, HC; Stelzer, MK, 2010)
"Ninety percent of anal cancer is associated with human papilloma viruses (HPVs)."	( Lambert, PF; Liem, A; Pitot, HC; Thomas, MK, 2011)
"Anal cancer is a rare tumour accounting for ∼2% of all colorectal cancers between 1997 and 2000 in the UK."	( Bhuva, NJ; Glynne-Jones, R; Harrison, MK; Sonoda, L; Wong, WL, 2012)
"Anal cancer is an increasing issue in HIV-positive men who have sex with men (MSM)."	( de Vries, HJ; Dijkgraaf, MG; Prins, JM; Richel, O; van Noesel, CJ, 2013)
"The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life."	( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013)
"The incidence of anal cancer is increasing especially in HIV-positive men having sex with men."	( den Hollander, JC; van der Ende, ME; van der Snoek, EM, 2015)
"The majority of anal cancers are squamous cell carcinomas, and they are treated according to stage."	( Abdayem, P; Antoun, J; Ghosn, M; Kourie, HR; Nasr, D, 2015)
"Anal cancer is uncommon."	( Abunassar, M; Asmis, T; Jonker, DJ; Reinders, J, 2015)
"However, anal cancers are rare in patients with HIV in Japan."	( Ishida, H; Mita, E; Mori, K; Nakazuru, S; Nishio, K; Sakakibara, Y; Sugimoto, A; Uehira, T; Yajima, K; Yamada, T, 2016)
"Anal cancer is a human papillomavirus (HPV)-mediated neoplasia of the anal squamous epithelium."	( Blizzard, L; Blomfield, P; Cornall, A; Simpson, S; Tabrizi, SN; Turner, R, 2016)
"The incidence of anal cancer is increasing in Western countries."	( Burkill, GJ; Dizdarevic, S; Gilbert, DC; Jones, JR; McKinna, F; Teagle, AR, 2016)
"CRT for anal cancer is becoming a standard therapy but local recurrence is possible."	( Aoyama, Y; Hikosaka, Y; Karamatsu, S; Katada, T; Kato, A; Mita, K; Nishida, T; Nishido, T; Saito, M; Sakamoto, S; Shibata, T; Teranishi, F; Tsuchiya, T, 2019)
"Anal cancer is a rare disease that has doubled in incidence over the last four decades."	( Behrenbruch, CC; Bernardi, MP; Chittleborough, TJ; Di Costanzo, N; Guerra, GR; Hawkes, D; Haynes, NM; Heriot, AG; Kong, JC; Liu, DS; Lupat, R; Millen, RM; Mitchell, C; Ngan, SY; Phillips, WA; Ramsay, RG; Read, M; Roth, S; Sampurno, S; Sia, J; Teh, J; Tothill, RW; Xu, H; Yu, J, 2021)
"Anal cancer is considered a rare tumor, accounting for 6 % of digestive cancers and about 2000 new cases per year in France."	( Combet-Curt, V; Delhiat, AC; Vendrely, V, 2022)
"Anal cancer is a rare disease with increasing incidence."	( Demes, M; Eichler, K; Jeroch, J; Martin, D; Pession, U; Schulze, F; Waidmann, O; Wild, P, 2022)
"Anal cancer is a rare form of gastrointestinal malignancy, and treatment is often confined to specialist centres."	( Elmasry, A; Giridharan, S; Patel, C, 2023)
"Anal dysplasia and anal cancer are major health problems."	( Auyeung, AS; Carchman, EH; Gunder, LC; Johnson, HR; Leverson, GE; Matkowskyj, KA; Moyer, TH; Zhang, W, 2023)
"Anal cancer is associated with high-risk human papillomavirus infection and oncoprotein expression."	( Carchman, EH; Gunder, LC; Johnson, HR; Leverson, GE, 2023)

Excerpt	Reference
"Incidence of anal cancer has remained stable, and it is now the third most common cancer in HIV-infected Australians."	( Grulich, AE; Kaldor, JM; Law, M; McDonald, AM; Middleton, MG; Vajdic, CM; van Leeuwen, MT, 2009)
"Incidence rates of anal cancer have progressively increased during the HIV epidemic."	( Agan, BK; Barthel, RV; Crum-Cianflone, NF; Ganesan, A; Hullsiek, KH; Marconi, VC; Weintrob, A, 2010)
"The incidence of anal cancer has been increasing among U."	( Franke, AA; Goodman, MT; Hernandez, BY; Shvetsov, YB; Thompson, PJ; Wilkens, LR; Zhu, X, 2010)

Excerpt	Reference
"The standard treatment for anal cancer is combination chemo-radiotherapy."	( Basrur, V; de Gara, CJ; Figueredo, A; Goodyear, M; Knight, P, 1995)
"Four hundred five patients with anal cancer were identified by computer search, and 204 (51%) were evaluable; 164 of 204 (80%) had squamous cell carcinoma, 137 of whom (84%) were treated with sphincter-preserving procedures, and 27 of whom (16%) were treated by by radical surgery."	( Coplin, MA; Johnson, FE; Longo, WE; Vernava, AM; Virgo, KS; Wade, TP, 1994)
"Patients diagnosed as having anal cancer and human immunodeficiency virus (HIV)-positive disease were evaluated for response to treatment and its associated toxicity."	( Berson, A; Chadha, M; Malamud, S; Pisch, J; Rosenblatt, EA, 1994)
"Mitomycin's role in anal cancer is being evaluated in a randomized clinical trial by the Radiation Therapy Oncology Group."	( Catton, CN; Cummings, BJ; Keane, TJ; O'Sullivan, B; Wong, CS, 1993)
"Non-surgical management of anal cancer by radiotherapy alone or combined with chemotherapy has, in uncontrolled studies, yielded similar local tumour control and survival rates to surgery."	( , 1996)
"Retrospective review of 50 MO anal cancer patients treated from 1984-1994."	( Constantinou, EC; Daly, W; DeLaney, TF; Fung, CY; Kaufman, DS; Willett, CG, 1997)
"From 1984 to 1994, 79 patients with anal cancer were treated with radical intent using radiotherapy (plus chemotherapy) at Beatson Oncology Centre, Glasgow, Scotland."	( McNee, SG; Paul, J; Reed, NS; Robertson, AG; Sandhu, AP; Symonds, RP, 1998)
"The effect of the treatment of anal cancer by performing a high-dose-rate (HDR) brachytherapy boost during a short split between the external beam radiotherapy series (EBR) +/- chemotherapy was investigated."	( Berger, A; Gebhart, FH; Geyer, E; Hebenstreit, J; Kapp, KS; Oechs, AC; Stoeger, H, 2001)
"Thirty-nine patients with anal canal cancers, stages T1-T4 N0-2 M0, were treated with split-course EBR (50-50."	( Berger, A; Gebhart, FH; Geyer, E; Hebenstreit, J; Kapp, KS; Oechs, AC; Stoeger, H, 2001)
"Treatment of T3 and T4 anal cancer with combined chemotherapy and EBRT, followed by interstitial implant results in an ultimate local-regional control of 84%, after the inclusion of selected APR."	( Cosmatos, HA; Hsiang, JY; Hwang, JM; Kagan, RA; Kaptein, JS; Rao, AR; Tome, M; Wang, R, 2004)
"Here, we report a case of a male with anal cancer who was treated with 5-FU 1000 mg/m(2), continuous infusion for 5 days q4 weeks."	( Choi, HJ; Chung, HC; Jeung, HC; Kim, YA; Rha, SY; Seong, JS, 2006)
"Metastatic anal cancer is a rare disease in the Western hemisphere and current treatment modalities are not effective."	( Catalano, PJ; Hahn, RG; Haller, D; Harris, J; Jhawer, M; Lefkopoulou, M; Mani, S, 2006)
"To this end, anal cancer is a disease best treated primarily with chemoradiation."	( Herman, J; Johnstone, PA; Konski, AA; Mohiuddin, M; Poggi, MM; Saltz, L; Suh, WW, 2007)
"We analyzed 48 consecutive anal cancer patients treated with concurrent chemotherapy and intensity-modulated radiation therapy."	( Aydogan, B; Chmura, SJ; Devisetty, K; Jani, AB; Kindler, HL; Mell, LK; Miller, RC; Mundt, AJ; Roeske, JC; Salama, JK; Schomas, DA, 2008)
"To assess the utility of FDG-PET in anal cancer for staging and impact on radiotherapy planning (RTP), response and detection of recurrent disease."	( Chao, M; Feigen, M; Joon, DL; Joon, ML; Kai, C; Khoo, V; Nguyen, BT; Quong, G; Rykers, K; Scott, A; See, A; Wada, M; Zupan, E, 2008)
"Although most patients with anal canal cancer are cured with sphincter-preserving, nonsurgical, combined-modality therapy, those with large tumors and lymph node involvement have a poor prognosis."	( Budinger, S; Colacchio, TA; Day, JM; Ellerton, J; Goldberg, RM; Hopkins, J; Mayer, RJ; Meropol, NJ; Niedzwiecki, D; Shank, B; Tepper, J; Valone, F, 2008)
"The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin."	( Czito, BG; Meyer, JJ; Pepek, JM; Willett, CG; Yoo, S, 2009)
"The first UKCCCR Anal Cancer Trial (1996) demonstrated the benefit of chemoradiation over radiotherapy (RT) alone for treating epidermoid anal cancer, and it became the standard treatment."	( Glynne-Jones, R; James, R; Jitlal, M; Ledermann, J; Meadows, H; Northover, J; Sebag-Montefiore, D; Wan, S, 2010)
"Standard treatment for anal canal cancer is definitive radiochemotherapy (RCT) with 5-fluorouracil plus mitomycin C."	( Rödel, C, 2010)
"Eighty-four patients with invasive anal cancer treated with definitive external beam radiotherapy (RT) with a mandatory split of 12 days (52 patients, Montreal, Canada) or without an intended split (32 patients, Zurich, Switzerland) were reviewed."	( Bahary, JP; Ciernik, IF; Donath, D; Lütolf, UM; Oehler, C; Provencher, S, 2010)
"From 1991 to 2005, 58 patients with anal cancer were curatively treated with CRT."	( Donath, D; Fortin, B; Jolicoeur, M; Lavertu, S; Oehler, C; Provencher, S, 2010)
"HIV-positive patients with anal cancer can be treated with standard CRT, with the same tolerability and toxicity as HIV-negative patients."	( Fraunholz, I; Gerstein, J; Haberl, A; Jäck, K; Rabeneck, D; Rödel, C; Weiss, C, 2011)
"A total of 88 patients treated for anal cancer at our institution between 1990 and 2006 were identified from our database."	( Hägele, V; Mai, SK; Welzel, G; Wenz, F, 2011)
"Pre- and post-treatment staging of anal cancer are often inaccurate."	( Baccega, M; Bellò, M; Cassoni, P; Cravero, F; Filippini, C; Fora, G; Lesca, A; Milanesi, E; Mistrangelo, M; Morino, M; Munoz, FH; Pelosi, E; Racca, P; Ricardi, U; Skanjeti, A, 2012)
"At pretreatment assessment, anal cancer was identified by PET-CT in 47 patients (88."	( Baccega, M; Bellò, M; Cassoni, P; Cravero, F; Filippini, C; Fora, G; Lesca, A; Milanesi, E; Mistrangelo, M; Morino, M; Munoz, FH; Pelosi, E; Racca, P; Ricardi, U; Skanjeti, A, 2012)
"Fifty-eight anal cancer patients were treated with concurrent chemotherapy and IMRT."	( Beriwal, S; DeFoe, SG; Heron, DE; Kabolizadeh, P, 2013)
"The treatment of anal cancer is based on concomitant radiotherapy and chemotherapy and is associated with a nonnegligible rate of local severe toxicities that can strongly impair the quality of life."	( Benezery, K; Doyen, J; Follana, P; Francois, E; Gal, J; Gérard, JP; Hannoun-Levi, JM; Ortholan, C, 2013)
"The majority of anal cancers are squamous cell carcinomas, and they are treated according to stage."	( Abdayem, P; Antoun, J; Ghosn, M; Kourie, HR; Nasr, D, 2015)
"All patients displayed squamous anal cancer and were treated with MMC alone or MMC plus 5-fluoruracil."	( Antigny, F; Chaumais, MC; Cottin, V; Dorfmüller, P; Girerd, B; Godinas, L; Günther, S; Hautefort, A; Humbert, M; Jaïs, X; Montani, D; Perros, F; Ranchoux, B; Raymond, N; Savale, L; Simonneau, G; Sitbon, O, 2015)
"TomoTherapy for locally advanced anal cancer is feasible."	( Belhomme, S; Benech, J; Doussau, A; Frison, E; Henriques de Figueiredo, B; Kantor, G; Lisbona, A; Mahé, MA; Maire, JP; Nomikossoff, N; Rio, E; Vendrely, V, 2015)
"Patients with SCC of anal cancer T2-4N0M0 or T (any) N1-3M0, with good performance status and normal blood and renal function, were treated with capecitabine 825 mg/m(2) bid during radiotherapy associated with a single dose of mitomycin 15 mg/m(2) on day 1."	( Alex, AK; Bariani, G; Braghirolli, MI; Hoff, PM; Moniz, CM; Nahas, C; Oliveira, SC; Riechelmann, R, 2016)
"45 patients with anal cancer who underwent pre-treatment FDG-PET/CT were included."	( Behrendt, FF; Eble, MJ; Heinzel, A; Mohammadkhani Shali, S; Mottaghy, FM; Schmitt, V; Verburg, FA; Winz, OH, 2016)
"Fifty-six anal cancer patients from 2 institutions received definitive radiation therapy (median primary dose of 54 Gy) using intensity modulated radiation therapy (IMRT, n=49) or 3-dimensional (3D) conformal therapy (n=7) with concurrent 5-fluorouracil (5-FU) and mitomycin C."	( Aggarwal, S; Bazan, JG; Chang, DT; Golden, DW; Kopec, M; Lee, AY; Liauw, SL; Pelizzari, CA, 2017)
"Although treatment of localized anal cancer (AC) is well established, very little evidence is available to inform the management of advanced tumors, and the prognosis of these patients remains poor."	( Baratelli, C; Chau, I; Cunningham, D; Kalaitzaki, E; Morano, F; Rao, S; Sclafani, F; Starling, N; Watkins, D, 2017)
"Standard treatment for locally advanced anal cancer is chemoradiotherapy with mitomycin C and fluorouracil."	( Chong, LC; Healey, T; Michele, T; Price, TJ, 2017)
"A retrospective cohort of 190 anal cancer patients treated at 3 academic centers with concurrent chemo-RT employing either SIB or SeqB was analysed."	( Arcadipane, F; Casadei Gardini, A; Cassoni, P; Ceccarelli, M; Créhange, G; De Bari, B; Evangelista, A; Franco, P; Furfaro, G; Iorio, GC; Lepinoy, A; Martini, S; Mistrangelo, M; Passardi, A; Ricardi, U; Trino, E; Valgiusti, M, 2018)
"For 70 women with anal cancer treated at our department, acute and chronic side effects and quality of life (QoL) were evaluated with questionnaires using the Common Terminology Criteria for Adverse Events (CTCAE v."	( Adeberg, S; Debus, J; Haefner, MF; Herfarth, K; Koerber, SA; Krug, D; Liermann, J; Seither, B; Slynko, A; Sterzing, F, 2019)
"Pre-treatment PET parameters of anal cancer showed a predictive role independent of clinicopathological factors."	( Guren, MG; Hernes, E; Klotz, D; Malinen, E; Rekstad, BL; Rusten, E; Undseth, C, 2019)
"CRT for anal cancer is becoming a standard therapy but local recurrence is possible."	( Aoyama, Y; Hikosaka, Y; Karamatsu, S; Katada, T; Kato, A; Mita, K; Nishida, T; Nishido, T; Saito, M; Sakamoto, S; Shibata, T; Teranishi, F; Tsuchiya, T, 2019)
"Definitive chemoradiation for anal cancer is effective but may be associated with toxic effects, and some patients may not be able to complete the planned treatment."	( Booth, CM; Brogly, SB; Hanna, TP; Kalyvas, M; Ko, G; Li, W; Patel, SV; Raphael, MJ, 2020)
"Overall, 1125 patients with stage I-III anal cancer were treated with curative-intent radiation."	( Booth, CM; Brogly, SB; Hanna, TP; Kalyvas, M; Ko, G; Li, W; Patel, SV; Raphael, MJ, 2020)
"Among patients with anal cancer, chemoradiotherapy is often associated with toxicities that diminish quality of life."	( Abi Jaoude, J; Colbert, LE; Das, P; El Alam, MB; Holliday, EB; Klopp, AH; Koay, EJ; Kouzy, R; Lin, D; Minsky, BD; Taniguchi, CM, 2020)
"The GI-related PROs of patients with anal cancer tend to fluctuate during radiotherapy but return to baseline by 3 months, at which time most patients report few or no residual adverse effects."	( Abi Jaoude, J; Colbert, LE; Das, P; El Alam, MB; Holliday, EB; Klopp, AH; Koay, EJ; Kouzy, R; Lin, D; Minsky, BD; Taniguchi, CM, 2020)
"One hundred and ninety-three rectal and anal cancer patients who received radiotherapy were prospectively enrolled from January 2019 to December 2020."	( Fan, XJ; Liu, S; Liu, YP; Shi, ST; Song, YW; Wang, YL; Zeng, GD; Zhang, XD; Zheng, J, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	168 (17.39)	23.3326
1990's	138 (14.29)	12.5806
2000's	210 (21.74)	18.1394
2010's	360 (37.27)	28.8240
2020's	90 (9.32)	9.53

Drug	Relationship Strength	Studies	Trials
dinitrochlorobenzene	medium	2	1
aminolevulinic acid	low	7	0
acetic acid	medium	7	1
arsenic acid	low	1	0
salicylic acid	low	1	0
creatine	low	1	0
cytosine	medium	9	2
dimethyl sulfoxide	low	1	0
formaldehyde	medium	7	1
niacinamide	low	2	0
nitrates	medium	3	1
nitrous oxide	low	1	0
sulfites	low	1	0
uracil	low	3	0
1,2-dimethylhydrazine	low	3	0
3-methylcholanthrene	low	1	0
acetaminophen	low	2	0
amantadine	low	1	0
diatrizoic acid	low	1	0
amifostine anhydrous	low	1	0
anastrozole	low	1	0
azathioprine	low	3	0
bupivacaine	low	2	0
candesartan	low	1	0
carvedilol	low	1	0
chloroquine	low	1	0
cimetidine	low	1	0
ciprofloxacin	low	1	0
pentetic acid	low	2	0
fluorouracil	medium	429	76
furosemide	low	2	0
gentamicin	medium	2	1
guaifenesin	low	3	0
hydroxyurea	low	1	0
lidocaine	low	2	0
ifosfamide	low	1	0
indole-3-carbinol	low	1	0
indomethacin	low	1	0
lomustine	medium	1	1
mepivacaine	low	1	0
metformin	low	1	0
metronidazole	low	1	0
mitoxantrone	low	1	0
neostigmine	low	1	0
oxonic acid	medium	8	1
pentoxifylline	low	1	0
protoporphyrin ix	low	1	0
semustine	medium	3	1
sulfadiazine	medium	1	1
gatifloxacin	low	1	0
tegafur	medium	11	1
temozolomide	low	2	0
thiotepa	low	2	0
mitomycin	medium	291	46
prednisolone	low	1	0
thymidine	low	3	0
floxuridine	low	2	0
trichlorfon	low	1	0
prednisone	low	2	0
penicillin g	low	1	0
chloramphenicol	low	1	0
glutamine	low	1	0
lysine	low	1	0
9,10-dimethyl-1,2-benzanthracene	low	5	0
uridine	low	3	0
levodopa	low	1	0
tyrosine	low	1	0
methylene blue	low	1	0
leucine	low	2	0
colchicine	low	2	0
cytarabine	low	1	0
trichloroacetic acid	low	6	0
dichloroacetic acid	low	1	0
methylprednisolone	low	2	0
catechin	low	1	0
quinazolines	medium	1	1
thiazoles	low	1	0
pyrimidine	low	1	0
hydrazine	low	2	0
hematoxylin	low	1	0
podophyllotoxin	medium	4	1
medroxyprogesterone	low	1	0
eosine yellowish-(ys)	low	1	0
lithium carbonate	low	1	0
galactitol	medium	1	1
c.i. 42510	low	3	0
nitrosoguanidines	low	1	0
deoxycytidine	medium	14	2
deoxyuridine	low	1	0
zinc oxide	low	1	0
tocopherols	low	2	0
digoxigenin	low	1	0
doxifluridine	low	1	0
pn 401	low	2	0
bonafton	low	1	0
iridium	low	10	0
neodymium	low	2	0
platinum	medium	3	1
silver	medium	1	1
technetium	low	1	0
argon	low	1	0
gadolinium	low	1	0
yttrium	low	1	0
camptothecin	medium	5	2
barium sulfate	low	11	0
silver nitrate	low	1	0
radon	low	1	0
clodronic acid	low	1	0
levamisole	low	1	0
iodine	low	2	0
daunorubicin	low	2	0
phenyl acetate	medium	6	1
prospidium	low	1	0
glutamic acid	low	1	0
paclitaxel	medium	18	1
etoposide	low	3	0
diltiazem	low	1	0
nimustine	low	3	0
vindesine	low	1	0
epirubicin	low	1	0
4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone	low	1	0
iso-sulfan blue	low	2	0
imiquimod	medium	40	5
cidofovir anhydrous	medium	10	2
gemcitabine	low	2	0
temoporfin	low	2	0
irinotecan	medium	4	1
capecitabine	medium	30	6
dimethylhydrazines	low	7	0
metaperiodate	low	1	0
iridium radioisotopes	medium	22	2
triazoles	low	1	0
fluorodeoxyglucose f18	medium	63	4
nsc-172755	low	1	0
fibrinogen	low	2	0
succinyl-coenzyme a	low	2	0
cobalt	low	1	0
hydrogen sulfite	low	1	0
bosentan anhydrous	low	1	0
fingolimod hydrochloride	low	1	0
imatinib mesylate	low	11	0
methotrexate	medium	3	1
docetaxel anhydrous	medium	9	3
singlet oxygen	low	1	0
biotin	low	3	0
organophosphonates	medium	9	2
lapatinib	medium	1	1
sorafenib	low	2	0
demecolcine	low	2	0
nsc 74859	low	1	0
ritonavir	low	1	0
carboplatin	low	15	0
saquinavir	low	1	0
retinol	low	1	0
tacrolimus	low	1	0
thymopentin	low	1	0
dactinomycin	low	2	0
melphalan	medium	2	1
bromochloroacetic acid	low	25	0
isomethyleugenol	low	1	0
enclomiphene	low	1	0
indigo carmine	low	1	0
tamoxifen	low	1	0
dasatinib	low	1	0
2-fluoro-2-deoxyglucose-6-phosphate	low	1	0
naphthoquinones	low	1	0
dinoprostone	low	1	0
pulmicort	low	1	0
etretinate	low	3	0
isotretinoin	low	1	0
acitretin	low	2	0
hydromorphone	low	1	0
naloxone	low	1	0
oxycodone	low	1	0
sirolimus	low	2	0
morphine	low	3	0
cesium	low	1	0
barium	low	1	0
naltrexone	low	1	0
sulfur	low	1	0
methylazoxymethanol acetate	low	1	0
radium	low	8	0
involucrin	low	1	0
beta-escin	medium	1	1
gadolinium dtpa	low	1	0
edotecarin	low	1	0
remimazolam	medium	1	1
lipid a	medium	2	1
mart-1 antigen	medium	3	1
g(m2) ganglioside	low	1	0
tofacitinib	low	1	0
indocyanine green	low	4	0
dactolisib	low	1	0
podophyllin	medium	14	3
acid phosphatase	low	3	0
(dtpa-phe(1))-octreotide	low	1	0
oligonucleotides	low	1	0
fibrinopeptide a	low	1	0
plx4032	low	1	0
glycolipids	low	1	0
piperidines	low	3	0
interleukin-8	low	1	0
chymostatin	low	1	0
ascorbic acid	low	1	0
tetracycline	low	1	0
salicylates	low	1	0
warfarin	low	1	0
s 1 (combination)	medium	8	1
epidermal growth factor	low	2	0
transforming growth factor beta	low	2	0
agar	low	1	0
cyclin d1	low	2	0
technetium tc 99m sulfur colloid	low	6	0
lewis x antigen	low	2	0
vitamin b 12	low	2	0
muramidase	low	1	0
nedaplatin	low	2	0
exudates	low	1	0
acyclovir	low	3	0
levoleucovorin	medium	17	4
dacarbazine	low	10	0
eye	low	1	0

Protein Targets (1,879)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Luciferase	23	0	0	23
pregnane X receptor	7	0	0	7
phosphopantetheinyl transferase	20	0	0	20
RAR-related orphan receptor gamma	53	0	0	53
SMAD family member 2	21	0	0	21
SMAD family member 3	21	0	0	21
TDP1 protein	65	0	0	65
Microtubule-associated protein tau	23	0	0	23
AR protein	66	0	0	66
caspase 7, apoptosis-related cysteine protease	12	0	0	12
aldehyde dehydrogenase 1 family, member A1	28	0	0	28
nuclear receptor subfamily 1, group I, member 3	39	0	0	39
retinoic acid nuclear receptor alpha variant 1	50	0	0	50
estrogen-related nuclear receptor alpha	58	0	0	58
farnesoid X nuclear receptor	36	0	0	36
pregnane X nuclear receptor	46	0	0	46
estrogen nuclear receptor alpha	80	0	0	80
peroxisome proliferator-activated receptor delta	31	0	0	31
peroxisome proliferator activated receptor gamma	39	0	0	39
caspase-3	12	0	0	12
euchromatic histone-lysine N-methyltransferase 2	47	0	0	47
aryl hydrocarbon receptor	28	0	0	28
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	34	0	0	34
activating transcription factor 6	27	0	0	27
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	18	0	0	18
thyroid hormone receptor beta isoform a	14	0	0	14
heat shock protein beta-1	19	0	0	19
nuclear factor erythroid 2-related factor 2 isoform 1	46	0	0	46
Voltage-dependent calcium channel gamma-2 subunit	34	0	0	34
Cellular tumor antigen p53	51	0	0	51
Cytochrome P450 1A2	0	5	0	6
Tyrosine-protein kinase Lck	0	8	8	16
Tyrosine-protein kinase Fyn	0	9	8	17
Aldo-keto reductase family 1 member B1	0	13	0	13
Adenosine receptor A3	0	10	0	10
Alpha-1B adrenergic receptor	0	14	0	14
Glutamate receptor 2	35	2	1	38
Acetylcholinesterase	0	7	0	7
Sodium-dependent noradrenaline transporter	0	12	2	14
Aryl hydrocarbon receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	14	0	14
Chain A, Beta-lactamase	18	0	0	18
Chain A, HADH2 protein	15	0	0	15
Chain B, HADH2 protein	15	0	0	15
Chain A, JmjC domain-containing histone demethylation protein 3A	14	0	0	14
Chain A, Cruzipain	11	0	0	11
acid sphingomyelinase	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	23	0	0	23
ATAD5 protein, partial	16	0	0	16
GLI family zinc finger 3	48	0	0	48
apical membrane antigen 1, AMA1	8	0	0	8
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
thyroid stimulating hormone receptor	18	0	0	18
estrogen receptor 2 (ER beta)	30	0	0	30
progesterone receptor	35	0	0	35
glucocorticoid receptor [Homo sapiens]	50	0	0	50
retinoid X nuclear receptor alpha	41	0	0	41
glucocerebrosidase	10	0	0	10
bromodomain adjacent to zinc finger domain 2B	9	0	0	9
P53	2	0	0	2
vitamin D (1,25- dihydroxyvitamin D3) receptor	33	0	0	33
IDH1	20	0	0	20
thyroid stimulating hormone receptor	21	0	0	21
v-jun sarcoma virus 17 oncogene homolog (avian)	20	0	0	20
Caspase-7	7	0	0	7
serine-protein kinase ATM isoform a	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	10	0	0	10
chromobox protein homolog 1	25	0	0	25
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	10	0	0	10
caspase-3	7	0	0	7
thyroid hormone receptor beta isoform 2	49	0	0	49
mitogen-activated protein kinase 1	12	0	0	12
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
ras-related protein Rab-9A	9	0	0	9
urokinase-type plasminogen activator precursor	11	0	0	11
plasminogen precursor	11	0	0	11
urokinase plasminogen activator surface receptor precursor	11	0	0	11
nuclear receptor ROR-gamma isoform 1	19	0	0	19
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
geminin	59	0	0	59
cytochrome P450 3A4 isoform 1	19	0	0	19
caspase-1 isoform alpha precursor	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	19	1	0	20
Gamma-aminobutyric acid receptor subunit beta-1	19	1	0	20
Gamma-aminobutyric acid receptor subunit delta	19	1	0	20
Gamma-aminobutyric acid receptor subunit gamma-2	19	1	0	20
Gamma-aminobutyric acid receptor subunit alpha-5	19	1	0	20
Gamma-aminobutyric acid receptor subunit alpha-3	19	1	0	20
Gamma-aminobutyric acid receptor subunit gamma-1	19	1	0	20
Gamma-aminobutyric acid receptor subunit alpha-2	19	1	0	20
Gamma-aminobutyric acid receptor subunit alpha-4	19	1	0	20
Gamma-aminobutyric acid receptor subunit gamma-3	19	1	0	20
Gamma-aminobutyric acid receptor subunit alpha-6	19	1	0	20
Nuclear receptor ROR-gamma	11	0	0	11
Caspase-7	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	19	1	0	20
Gamma-aminobutyric acid receptor subunit beta-3	19	1	0	20
Gamma-aminobutyric acid receptor subunit beta-2	19	1	0	20
GABA theta subunit	19	1	0	20
ATPase family AAA domain-containing protein 5	29	0	0	29
Ataxin-2	33	0	0	33
Gamma-aminobutyric acid receptor subunit epsilon	19	1	0	20
GLS protein	17	0	0	17
Smad3	16	0	0	16
EWS/FLI fusion protein	37	0	0	37
peripheral myelin protein 22	30	0	0	30
ATP-binding cassette sub-family C member 3	0	55	0	55
Multidrug resistance-associated protein 4	0	55	0	57
Solute carrier family 22 member 6	0	7	0	9
Carbonic anhydrase 12	0	4	0	7
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	9	0	9
Bile salt export pump	0	67	0	67
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	12	0	17
Carbonic anhydrase 2	0	13	1	20
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Prostaglandin G/H synthase 1	0	4	1	6
Carbonic anhydrase 3	0	3	0	5
Cytochrome P450 3A4	0	23	2	28
Cytochrome P450 2D6	0	11	0	12
Cytochrome P450 2C9	0	16	0	16
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Sulfotransferase 1A1	0	0	0	2
UDP-glucuronosyltransferase 1-6	0	1	0	2
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	6
Carbonic anhydrase 4	0	9	0	12
Prostaglandin G/H synthase 1	0	6	0	6
Carbonic anhydrase 6	0	5	0	8
Carbonic anhydrase 5A, mitochondrial	0	5	0	8
Prostaglandin G/H synthase 2	0	5	5	11
Carbonic anhydrase 7	0	4	0	7
Cytochrome P450 2J2	0	7	0	7
Carbonic anhydrase 9	0	7	0	11
Canalicular multispecific organic anion transporter 1	0	54	0	55
Carbonic anhydrase 15	0	5	0	7
Carbonic anhydrase 13	0	3	0	5
Carbonic anhydrase 14	0	3	0	6
Carbonic anhydrase 5B, mitochondrial	0	3	0	6
toxin B	0	0	0	1
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Fibrinogen C domain-containing protein 1	0	1	0	1
USP1 protein, partial	20	0	0	20
vitamin D3 receptor isoform VDRA	22	0	0	22
flap endonuclease 1	19	0	0	19
serine/threonine-protein kinase PLK1	5	0	0	5
eyes absent homolog 2 isoform a	1	0	0	1
DNA polymerase eta isoform 1	11	0	0	11
survival motor neuron protein isoform d	20	0	0	20
histone acetyltransferase KAT2A isoform 1	15	0	0	15
Rap guanine nucleotide exchange factor 3	6	0	0	6
Rap guanine nucleotide exchange factor 4	4	0	0	4
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	9	0	0	9
Chain A, Ferritin light chain	16	0	0	16
Thymidine kinase	0	3	0	4
thioredoxin reductase	33	0	0	33
arylsulfatase A	16	0	0	16
Histone H2A.x	24	0	0	24
Bloom syndrome protein isoform 1	16	0	0	16
hemoglobin subunit beta	5	0	0	5
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
lamin isoform A-delta10	37	0	0	37
Solute carrier family 22 member 1	0	12	0	16
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	3	0	7
POU domain, class 2, transcription factor 2	0	0	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	4	0	8
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	5	0	10
Thymidine kinase	0	2	0	3
acetylcholinesterase	20	0	0	20
NFKB1 protein, partial	8	0	0	8
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
regulator of G-protein signaling 4	15	0	0	15
putative alpha-glucosidase	2	0	0	2
Solute carrier family 22 member 2	0	8	0	11
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Glutamate receptor ionotropic, NMDA 1	0	3	1	7
Spike glycoprotein	25	1	5	31
Glutamate receptor ionotropic, NMDA 2A	0	3	1	7
Glutamate receptor ionotropic, NMDA 2B	0	4	1	8
Glutamate receptor ionotropic, NMDA 2C	0	3	1	7
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	3	1	7
Solute carrier family 22 member 1	0	4	0	5
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	3	1	7
Multidrug and toxin extrusion protein 1	0	10	0	10
Solute carrier family 22 member 2	0	3	0	3
Glutamate receptor ionotropic, NMDA 3A	0	3	1	7
ATP-dependent phosphofructokinase	22	0	0	22
muscarinic acetylcholine receptor M1	10	0	0	10
D(3) dopamine receptor	0	10	0	10
Gamma-aminobutyric acid receptor subunit rho-1	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 2	0	3	1	4
Glutamate receptor 3	0	2	1	3
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Solute carrier family 15 member 1	0	4	0	4
Glutamate receptor 4	0	3	1	4
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 2	0	2	0	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	30	0	0	30
cytochrome P450 family 3 subfamily A polypeptide 4	35	0	0	35
G	22	0	0	22
Interferon beta	41	0	0	41
HLA class I histocompatibility antigen, B alpha chain	22	0	0	22
Aromatase	0	4	0	4
Amine oxidase [flavin-containing] A	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	2	0	4
Inositol hexakisphosphate kinase 1	22	0	0	22
cytochrome P450 2C9, partial	22	0	0	22
Chain A, Hyaluronidase, phage associated	0	1	0	1
thioredoxin glutathione reductase	9	0	0	9
nuclear factor erythroid 2-related factor 2 isoform 2	21	0	0	21
lethal factor (plasmid)	10	0	0	10
Polyphenol oxidase 2	0	2	0	5
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	2
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	2	0	2
Alpha-2B adrenergic receptor	0	11	1	12
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	16	0	0	16
interleukin 8	10	0	0	10
Fumarate hydratase	18	0	0	18
polyprotein	18	0	0	18
peripheral myelin protein 22 isoform 1	12	0	0	12
cellular tumor antigen p53 isoform a	9	0	0	9
DNA polymerase iota isoform a (long)	24	0	0	24
M-phase phosphoprotein 8	11	0	0	11
muscleblind-like protein 1 isoform 1	12	0	0	12
Protein-arginine deiminase type-4	0	3	0	3
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	2	0	2
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Replicase polyprotein 1ab	0	2	5	7
Replicase polyprotein 1ab	0	4	5	9
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Endothelin receptor type B	1	1	0	2
Endothelin receptor type B	0	2	1	3
Endothelin-1 receptor	0	2	0	2
Endothelin-1 receptor	1	2	1	4
Endothelin receptor type B	0	0	1	1
Deoxyhypusine synthase	0	1	0	1
Sodium/bile acid cotransporter	0	3	0	3
Endothelin-1 receptor	0	1	0	1
Potassium channel subfamily K member 3	0	4	0	4
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	1	3
Potassium channel subfamily K member 9	0	1	0	1
nuclear receptor subfamily 1, group I, member 2	13	0	0	13
Chain A, 2-oxoglutarate Oxygenase	15	0	0	15
DNA topoisomerase	0	1	0	1
15-lipoxygenase, partial	12	0	0	12
PPM1D protein	21	0	0	21
Thrombopoietin	5	0	0	5
67.9K protein	26	0	0	26
alpha-galactosidase	5	0	0	5
lysosomal alpha-glucosidase preproprotein	3	0	0	3
cytochrome P450 2C19 precursor	5	0	0	5
huntingtin isoform 2	8	0	0	8
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
serine/threonine-protein kinase mTOR isoform 1	11	0	0	11
relaxin receptor 1 isoform 1	2	0	0	2
Telomerase reverse transcriptase	0	1	0	1
Serine/threonine-protein kinase Chk1	0	1	8	9
Histone deacetylase 3	0	2	0	2
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
Prothrombin	0	1	2	5
DNA ligase	0	2	0	2
Integrin beta-3	7	1	1	9
Integrin alpha-IIb	7	0	1	8
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	2	2	10
DNA topoisomerase 2-alpha	0	4	8	23
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
5-hydroxytryptamine receptor 2B	0	11	0	11
Type-2 restriction enzyme HindIII	0	1	0	1
D(1A) dopamine receptor	4	1	0	5
Histone deacetylase 4	0	2	0	2
Ribonuclease pancreatic	0	1	0	1
Inositol monophosphatase 1	9	0	0	9
DNA topoisomerase 2-beta	0	1	9	18
DNA topoisomerase 1	0	1	1	3
Histone deacetylase 1	0	3	0	3
DNA topoisomerase 1	0	1	0	1
Integrase	0	5	0	5
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	2	0	2
DNA topoisomerase type IB small subunit	0	0	1	1
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	3	0	3
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Histone deacetylase 6	0	4	0	4
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
cytochrome P450 2D6	24	0	0	24
potassium voltage-gated channel subfamily H member 2 isoform d	8	0	0	8
Epidermal growth factor receptor	0	16	7	23
Receptor tyrosine-protein kinase erbB-2	0	9	4	13
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-3 adrenergic receptor	0	8	1	9
5-hydroxytryptamine receptor 1A	0	8	0	8
Thromboxane-A synthase	0	5	0	5
Type-1A angiotensin II receptor	0	0	1	1
Type-1 angiotensin II receptor	0	2	0	3
Type-1 angiotensin II receptor	0	1	0	1
Type-2 angiotensin II receptor	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	4	0	4
Thiosulfate sulfurtransferase	0	3	0	3
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Leukotriene B4 receptor 2	0	0	1	1
Liver carboxylesterase 1	0	0	0	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	10	0	0	10
histone-lysine N-methyltransferase 2A isoform 2 precursor	10	0	0	10
DNA polymerase kappa isoform 1	15	0	0	15
D(1A) dopamine receptor	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
Toll-like receptor 4	0	2	0	2
5-hydroxytryptamine receptor 4	0	8	0	8
Amyloid-beta precursor protein	2	5	0	7
Beta-2 adrenergic receptor	0	2	1	3
ATP-dependent translocase ABCB1	0	17	2	26
Beta-1 adrenergic receptor	0	4	1	5
Alpha-2A adrenergic receptor	0	11	1	12
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Angiotensin-converting enzyme	0	6	0	6
D(2) dopamine receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	9	0	9
D(1A) dopamine receptor	0	4	0	4
Alpha-1D adrenergic receptor	0	6	0	6
5-hydroxytryptamine receptor 2A	0	7	0	7
5-hydroxytryptamine receptor 2C	0	9	0	9
5-hydroxytryptamine receptor 1B	0	6	0	6
Sodium-dependent serotonin transporter	0	6	0	6
5-hydroxytryptamine receptor 6	0	7	0	7
Potassium channel subfamily K member 10	0	1	0	1
Sodium-dependent dopamine transporter	0	8	0	8
Potassium voltage-gated channel subfamily H member 2	0	19	0	20
Cytochrome P450 1B1	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
DNA polymerase beta	6	0	0	6
neuropeptide S receptor isoform A	6	0	0	6
Prostaglandin G/H synthase 1	0	2	0	3
Arginase	0	2	0	2
Pancreatic triacylglycerol lipase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Adenosine receptor A1	0	2	0	4
Adenosine receptor A2a	0	2	0	4
Mu-type opioid receptor	0	14	6	25
Delta-type opioid receptor	0	13	5	23
Kappa-type opioid receptor	0	13	6	25
Xanthine dehydrogenase/oxidase	0	1	0	1
Melatonin receptor type 1A	0	0	1	1
Melatonin receptor type 1B	0	0	1	1
Death-associated protein kinase 1	0	1	4	5
Beta-secretase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	3	0	3
Carbonic anhydrase 3	0	1	0	1
Dihydroorotate dehydrogenase	0	2	0	2
streptokinase A precursor	0	0	5	5
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
50S ribosomal protein L36 2	0	2	0	2
Methionine--tRNA ligase, mitochondrial	0	0	1	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	1	5	6
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	1	5	6
Dihydrofolate reductase	0	2	0	2
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	1	0	2
Procathepsin L	0	2	5	7
Muscarinic acetylcholine receptor M2	0	8	0	8
Muscarinic acetylcholine receptor M4	0	9	0	9
Muscarinic acetylcholine receptor M5	0	5	0	5
Replicase polyprotein 1a	0	1	5	6
Replicase polyprotein 1ab	0	1	5	6
Replicase polyprotein 1ab	0	2	5	7
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	7	0	7
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	7	8
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	5	0	5
Serine/threonine-protein kinase mTOR	0	7	5	12
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	8	0	8
Angiotensin-converting enzyme 2	0	1	5	6
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Thymidine kinase	0	0	0	3
Solute carrier family 22 member 1	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
ATP-dependent translocase ABCB1	0	6	0	6
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	7	0	7
Histamine H2 receptor	0	6	0	6
Histamine H1 receptor	0	0	2	2
Histamine H2 receptor	11	2	1	14
Potassium-transporting ATPase subunit beta	0	1	0	1
Aldehyde oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	4	0	4
Histamine H4 receptor	0	1	0	1
Solute carrier family 22 member 11	0	1	0	4
Solute carrier family 22 member 4	0	1	0	1
Solute carrier family 22 member 8	0	3	0	4
cytochrome P450 2C9 precursor	4	0	0	4
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	3
DNA gyrase subunit A	0	2	0	4
DNA gyrase subunit B	0	2	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	2	0	4
DNA gyrase subunit A	0	1	0	3
Cytochrome P450 2C19	0	8	0	8
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Stromelysin-1	0	2	2	4
Matrix metalloproteinase-9	0	3	0	3
Macrophage metalloelastase	0	1	0	1
endonuclease IV	6	0	0	6
PAX8	0	0	0	4
cytochrome P450 2D6 isoform 1	5	0	0	5
nuclear receptor subfamily 0 group B member 1	0	3	0	3
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
steroidogenic factor 1	0	3	0	3
Solute carrier family 22 member 3	0	4	0	5
Tubulin alpha-1A chain	0	4	3	8
Tubulin beta chain	0	4	3	7
Plasma kallikrein	0	0	0	3
Tubulin beta-4A chain	0	4	4	11
Tubulin beta chain	0	4	4	11
Tubulin alpha-3C chain	0	4	4	11
Serine/threonine-protein kinase pim-1	0	1	7	8
Tubulin alpha-1B chain	0	4	4	11
Tubulin alpha-4A chain	0	4	4	11
Tubulin beta-4B chain	0	4	4	11
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	5	4	12
Tubulin beta-2A chain	0	4	4	11
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	4	4	11
Tubulin beta-2B chain	0	5	1	8
Tubulin alpha-3E chain	0	4	4	11
Tubulin alpha-1A chain	0	4	4	11
Similar to alpha-tubulin isoform 1	0	3	1	6
Similar to alpha-tubulin isoform 1	0	3	0	5
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	4	4	11
Tubulin beta-6 chain	0	4	4	11
Tubulin beta-2B chain	0	4	4	11
Tubulin beta-1 chain	0	4	4	11
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	3
glp-1 receptor, partial	15	0	0	15
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	4	0	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
transactivating tegument protein VP16 [Human herpesvirus 1]	0	4	0	4
nuclear receptor coactivator 3 isoform a	0	4	0	4
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	4	0	6
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	7	10
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	2	0	5
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Isocitrate lyase	0	1	0	1
RAD51	0	1	0	1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	4	7	11
Growth factor receptor-bound protein 2	0	1	0	1
Reverse transcriptase/RNaseH	0	2	1	3
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Bone morphogenetic protein receptor type-1B	0	0	7	7
Membrane-associated progesterone receptor component 1	0	0	6	6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	3	5	8
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	1	7	8
ATP-dependent RNA helicase DDX3X	0	0	7	7
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	4	5
Pyridoxal kinase	0	0	7	7
Citron Rho-interacting kinase	0	0	7	7
Aurora kinase A	0	3	7	10
Cyclin-G-associated kinase	0	0	7	7
Ephrin type-B receptor 6	0	0	7	7
Peroxisomal acyl-coenzyme A oxidase 3	0	0	7	7
Receptor-interacting serine/threonine-protein kinase 2	0	3	7	10
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	7	7
Dynamin-like 120 kDa protein, mitochondrial	0	0	7	7
Eukaryotic translation initiation factor 5B	0	0	4	4
Rho-associated protein kinase 2	0	1	7	8
Serine/threonine-protein kinase ULK1	0	0	7	7
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	7	7
Ribosomal protein S6 kinase alpha-5	0	1	7	8
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	7	7
Ribosomal protein S6 kinase alpha-4	0	0	7	7
Serine/threonine-protein kinase 16	0	0	7	7
Serine/threonine-protein kinase 10	0	0	7	7
Serine/threonine-protein kinase D3	0	2	7	9
Structural maintenance of chromosomes protein 2	0	0	6	6
Mitogen-activated protein kinase kinase kinase 6	0	0	7	7
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	7	7
Serine/threonine-protein kinase LATS1	0	0	7	7
Serine/threonine-protein kinase PAK 4	0	0	7	7
Tyrosine-protein kinase ABL1	0	9	10	20
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	7	7
Protein kinase C beta type	0	2	7	9
Insulin receptor	0	4	7	11
Cyclin-dependent kinase 1	0	0	7	7
Glycogen phosphorylase, liver form	0	0	7	7
Tyrosine-protein kinase Fes/Fps	0	0	7	7
Adenine phosphoribosyltransferase	0	0	6	6
Tyrosine-protein kinase Yes	0	1	7	8
Tyrosine-protein kinase Lyn	0	1	7	8
Proto-oncogene tyrosine-protein kinase receptor Ret	0	3	7	10
Insulin-like growth factor 1 receptor	0	2	7	9
Signal recognition particle receptor subunit alpha	0	0	5	5
Cytochrome c1, heme protein, mitochondrial	0	0	7	7
Hepatocyte growth factor receptor	0	1	7	8
Tyrosine-protein kinase HCK	0	3	7	10
Platelet-derived growth factor receptor beta	0	4	7	11
Serine/threonine-protein kinase A-Raf	0	2	7	9
Glycogen phosphorylase, brain form	0	0	7	7
Breakpoint cluster region protein	0	3	9	13
Fibroblast growth factor receptor 1	0	3	7	10
Cyclin-dependent kinase 4	0	1	7	8
ADP/ATP translocase 3	0	0	7	7
Inosine-5'-monophosphate dehydrogenase 2	0	0	6	6
Proto-oncogene tyrosine-protein kinase Src	0	5	7	12
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	6	6
Serine/threonine-protein kinase B-raf	0	4	9	14
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	7	7
Tyrosine-protein kinase Fer	0	0	7	7
Protein kinase C alpha type	0	4	7	11
cAMP-dependent protein kinase catalytic subunit alpha	0	0	7	7
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	7	7
Casein kinase II subunit alpha'	0	1	7	8
Ras-related protein Rab-6A	0	0	7	7
Ephrin type-A receptor 1	0	0	7	7
Multifunctional protein ADE2	0	0	7	7
cAMP-dependent protein kinase catalytic subunit gamma	0	0	5	5
cAMP-dependent protein kinase catalytic subunit beta	0	0	7	7
Ferrochelatase, mitochondrial	0	0	8	8
Tyrosine-protein kinase JAK1	0	3	8	13
Cyclin-dependent kinase 2	0	4	8	12
Beta-adrenergic receptor kinase 1	0	0	7	7
Probable ATP-dependent RNA helicase DDX6	0	0	7	7
Mitogen-activated protein kinase 3	0	1	7	8
MAP/microtubule affinity-regulating kinase 3	0	0	7	7
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	1	2
Mitogen-activated protein kinase 1	0	2	7	9
Ephrin type-A receptor 2	0	1	7	8
Ephrin type-B receptor 2	0	1	7	8
Non-receptor tyrosine-protein kinase TYK2	0	3	8	13
UMP-CMP kinase	0	0	5	5
Phosphatidylethanolamine-binding protein 1	0	0	5	5
Wee1-like protein kinase	0	0	7	7
Heme oxygenase 2	0	0	7	7
S-adenosylmethionine synthase isoform type-2	0	0	7	7
DnaJ homolog subfamily A member 1	0	0	7	7
RAC-alpha serine/threonine-protein kinase	0	2	7	9
RAC-beta serine/threonine-protein kinase	0	1	7	8
Dual specificity protein kinase TTK	0	0	6	6
DNA replication licensing factor MCM4	0	0	6	6
Myosin-10	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 2	0	2	7	9
Receptor-type tyrosine-protein kinase FLT3	0	3	7	10
Bone morphogenetic protein receptor type-1A	0	0	7	7
Activin receptor type-1B	0	0	7	7
TGF-beta receptor type-1	0	0	7	7
TGF-beta receptor type-2	0	0	7	7
Electron transfer flavoprotein subunit beta	0	0	6	6
Tyrosine-protein kinase CSK	0	2	7	9
Glycine--tRNA ligase	0	0	7	7
Protein kinase C iota type	0	2	7	9
Exosome RNA helicase MTR4	0	0	7	7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	4	5	9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	3	5	8
Tyrosine-protein kinase Tec	0	2	7	9
Tyrosine-protein kinase ABL2	0	1	7	8
Tyrosine-protein kinase FRK	0	0	7	7
Tyrosine-protein kinase SYK	0	1	7	8
26S proteasome regulatory subunit 6B	0	0	7	7
Mitogen-activated protein kinase 8	0	1	7	8
Mitogen-activated protein kinase 9	0	0	7	7
Dual specificity mitogen-activated protein kinase kinase 3	0	0	7	7
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	5	5
Casein kinase I isoform alpha	0	2	7	9
Casein kinase I isoform delta	0	0	7	7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	3	5	8
MAP kinase-activated protein kinase 2	0	2	7	9
Elongation factor Tu, mitochondrial	0	0	7	7
Choline-phosphate cytidylyltransferase A	0	0	4	4
Cysteine--tRNA ligase, cytoplasmic	0	0	7	7
Casein kinase I isoform epsilon	0	0	7	7
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	7	7
Dual specificity protein kinase CLK1	0	0	7	7
Dual specificity protein kinase CLK2	0	0	7	7
Glycogen synthase kinase-3 alpha	0	0	7	7
Glycogen synthase kinase-3 beta	0	2	7	9
Cyclin-dependent kinase 7	0	0	7	7
Cyclin-dependent kinase 9	0	0	7	7
Ras-related protein Rab-27A	0	0	6	6
Interleukin-1 receptor-associated kinase 1	0	0	7	7
Ribosomal protein S6 kinase alpha-3	0	2	7	9
Serine/threonine-protein kinase Nek2	0	0	7	7
Serine/threonine-protein kinase Nek3	0	0	7	7
Tyrosine-protein kinase JAK3	0	4	5	12
Dual specificity mitogen-activated protein kinase kinase 6	0	0	7	7
LIM domain kinase 1	0	1	7	8
LIM domain kinase 2	0	1	7	8
Tyrosine--tRNA ligase, cytoplasmic	0	0	7	7
5'-AMP-activated protein kinase subunit gamma-1	0	0	7	8
Ephrin type-B receptor 3	0	0	7	7
Ephrin type-A receptor 5	0	0	7	7
Ephrin type-B receptor 4	0	2	7	9
Ephrin type-A receptor 4	0	0	7	7
Adenylate kinase 2, mitochondrial	0	0	7	7
Adenosine kinase	0	0	7	7
Ras-related protein Rab-10	0	0	7	7
Actin-related protein 3	0	0	7	7
Actin-related protein 2	0	0	6	6
GTP-binding nuclear protein Ran	0	0	7	7
Cyclin-dependent kinase 3	0	0	6	6
Cyclin-dependent kinase 6	0	1	7	8
Cyclin-dependent-like kinase 5	0	1	7	8
Cyclin-dependent kinase 16	0	0	7	7
Cyclin-dependent kinase 17	0	0	7	7
ATP-dependent 6-phosphofructokinase, platelet type	0	0	7	7
Dual specificity mitogen-activated protein kinase kinase 1	0	3	7	10
Protein kinase C theta type	0	2	7	9
Activin receptor type-1	0	0	7	7
Macrophage-stimulating protein receptor	0	0	7	7
Focal adhesion kinase 1	0	1	7	8
Protein kinase C zeta type	0	3	5	8
Protein kinase C delta type	0	3	7	10
Tyrosine-protein kinase BTK	0	4	7	11
Activated CDC42 kinase 1	0	1	7	8
Epithelial discoidin domain-containing receptor 1	0	3	7	10
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	7	7
Serine/threonine-protein kinase 4	0	0	7	7
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	7	8
Dual specificity mitogen-activated protein kinase kinase 5	0	0	7	7
Mitogen-activated protein kinase 7	0	0	7	7
Serine/threonine-protein kinase PAK 2	0	0	7	7
Serine/threonine-protein kinase 3	0	0	7	7
Mitogen-activated protein kinase kinase kinase 1	0	0	7	7
Serine-protein kinase ATM	0	1	0	1
Integrin-linked protein kinase	0	0	7	7
Rho-associated protein kinase 1	0	0	7	7
Non-receptor tyrosine-protein kinase TNK1	0	0	7	7
Serine/threonine-protein kinase ATR	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	7	7
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	7	7
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	7	7
Activin receptor type-2B	0	0	7	7
Bone morphogenetic protein receptor type-2	0	0	7	7
Protein-tyrosine kinase 6	0	1	7	8
cGMP-dependent protein kinase 1	0	0	7	7
Cyclin-dependent kinase 13	0	0	7	7
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	7	7
Protein-tyrosine kinase 2-beta	0	0	7	7
Maternal embryonic leucine zipper kinase	0	0	7	7
Structural maintenance of chromosomes protein 1A	0	0	6	6
Chromodomain-helicase-DNA-binding protein 4	0	0	7	7
Peroxisomal acyl-coenzyme A oxidase 1	0	0	6	6
Serine/threonine-protein kinase 38	0	0	5	5
Ephrin type-A receptor 7	0	0	5	5
Delta(24)-sterol reductase	0	0	6	6
Ribosomal protein S6 kinase alpha-1	0	1	7	8
Dual specificity testis-specific protein kinase 1	0	0	6	6
Myosin light chain kinase, smooth muscle	0	0	7	7
Mitogen-activated protein kinase 11	0	2	7	9
Serine/threonine-protein kinase STK11	0	0	7	7
Serine/threonine-protein kinase N1	0	0	7	7
Serine/threonine-protein kinase N2	0	0	7	7
Mitogen-activated protein kinase 14	0	4	8	12
Calcium/calmodulin-dependent protein kinase type IV	0	0	7	7
Mitogen-activated protein kinase kinase kinase 11	0	0	7	7
MAP kinase-activated protein kinase 3	0	0	2	2
AP2-associated protein kinase 1	0	0	7	7
Myosin light chain kinase 3	0	0	7	7
Uncharacterized aarF domain-containing protein kinase 5	0	0	6	6
Putative heat shock protein HSP 90-beta 2	0	0	7	7
Rab-like protein 3	0	0	5	5
Serine/threonine-protein kinase MRCK alpha	0	0	7	7
Serine/threonine-protein kinase MRCK gamma	0	0	7	7
Acyl-CoA dehydrogenase family member 10	0	0	6	6
Serine/threonine-protein kinase N3	0	0	6	6
Serine/threonine-protein kinase ULK3	0	0	7	7
Uncharacterized protein FLJ45252	0	0	7	7
Acyl-CoA dehydrogenase family member 11	0	0	6	6
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	6	6
Serine/threonine-protein kinase MARK2	0	0	7	7
Serine/threonine-protein kinase TAO1	0	0	7	7
STE20-related kinase adapter protein alpha	0	0	7	7
Myosin-14	0	0	7	7
AarF domain-containing protein kinase 1	0	0	7	7
ATP-dependent RNA helicase DDX42	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	7	7
MAP kinase-activated protein kinase 5	0	1	7	8
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	4	4
Regulatory-associated protein of mTOR	0	2	0	2
Misshapen-like kinase 1	0	0	6	6
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	1	0	1
Atypical kinase COQ8A, mitochondrial	0	0	7	7
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	7	7
Mitogen-activated protein kinase 15	0	0	7	7
Serine/threonine-protein kinase Nek9	0	0	7	7
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
ATP-dependent RNA helicase DDX1	0	0	7	7
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	7	7
Aurora kinase B	0	1	7	8
MAP/microtubule affinity-regulating kinase 4	0	0	7	7
Serine/threonine-protein kinase Nek1	0	0	7	7
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	7	7
EKC/KEOPS complex subunit TP53RK	0	0	7	7
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	7	9
Mitogen-activated protein kinase kinase kinase 5	0	0	7	7
Mitogen-activated protein kinase kinase kinase 3	0	0	7	7
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	7	7
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	7	7
Serine/threonine-protein kinase D2	0	0	7	7
NUAK family SNF1-like kinase 2	0	0	6	6
RNA cytidine acetyltransferase	0	0	7	7
Serine/threonine-protein kinase SIK2	0	1	7	8
STE20-like serine/threonine-protein kinase	0	0	7	7
Serine/threonine-protein kinase TAO3	0	0	7	7
dCTP pyrophosphatase 1	0	0	7	7
Dual specificity protein kinase CLK4	0	0	7	7
Casein kinase I isoform gamma-1	0	0	7	7
Serine/threonine-protein kinase PAK 6	0	0	5	5
Phenylalanine--tRNA ligase beta subunit	0	0	7	7
Isoleucine--tRNA ligase, mitochondrial	0	0	5	5
BMP-2-inducible protein kinase	0	0	7	7
Obg-like ATPase 1	0	0	6	6
Midasin	0	0	7	7
Interleukin-1 receptor-associated kinase 4	0	0	7	7
Mitogen-activated protein kinase kinase kinase 20	0	1	7	8
Cyclin-dependent kinase 12	0	0	7	7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	6	6
Serine/threonine-protein kinase 26	0	0	7	7
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	7	7
Serine/threonine-protein kinase NLK	0	0	7	7
5'-AMP-activated protein kinase subunit gamma-2	0	0	7	8
Serine/threonine-protein kinase TBK1	0	1	7	8
Septin-9	0	0	7	7
Ribosomal protein S6 kinase alpha-6	0	0	7	7
TRAF2 and NCK-interacting protein kinase	0	0	7	7
Serine/threonine-protein kinase TAO2	0	0	7	7
Long-chain-fatty-acid--CoA ligase 5	0	0	6	6
Serine/threonine-protein kinase ICK	0	0	7	7
RAC-gamma serine/threonine-protein kinase	0	1	7	8
Serine/threonine-protein kinase 38-like	0	0	6	6
Serine/threonine-protein kinase SIK3	0	1	7	8
Mitogen-activated protein kinase kinase kinase 2	0	0	7	7
Thyroid hormone receptor-associated protein 3	0	0	7	7
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	7	7
Receptor-interacting serine/threonine-protein kinase 3	0	1	7	8
Serine/threonine-protein kinase MRCK beta	0	0	7	7
Interleukin-1 receptor-associated kinase 3	0	0	7	7
Serine/threonine-protein kinase 24	0	0	6	6
Casein kinase I isoform gamma-3	0	0	7	7
Mitogen-activated protein kinase kinase kinase 4	0	0	7	7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	1
Leukotriene C4 synthase	0	0	4	4
GALC protein	6	0	0	6
tyrosine-protein kinase Yes	6	0	0	6
Serine/threonine-protein kinase 25	0	0	4	4
Serine/threonine-protein kinase RIO3	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 7	0	1	4	5
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	4	6
Peripheral plasma membrane protein CASK	0	0	4	4
Serine/threonine-protein kinase DCLK1	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	4	5
Muscle, skeletal receptor tyrosine-protein kinase	0	0	4	4
Mitogen-activated protein kinase 13	0	2	4	6
3-phosphoinositide-dependent protein kinase 1	0	0	4	4
Mitogen-activated protein kinase kinase kinase 13	0	0	4	4
Death-associated protein kinase 3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
NUAK family SNF1-like kinase 1	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	4	4
Tyrosine-protein kinase JAK2	0	3	7	12
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	4	4
Serine/threonine-protein kinase PAK 3	0	0	4	4
Cyclin-dependent kinase-like 5	0	0	5	5
Serine/threonine-protein kinase 17B	0	0	4	4
Cyclin-dependent kinase 14	0	0	4	4
Serine/threonine-protein kinase OSR1	0	0	4	4
Serine/threonine-protein kinase Chk2	0	0	4	4
Tyrosine-protein kinase ABL1	0	2	0	2
Proto-oncogene tyrosine-protein kinase Src	0	1	1	2
Transthyretin	0	1	1	2
RAF proto-oncogene serine/threonine-protein kinase	0	4	5	10
High affinity nerve growth factor receptor	0	0	6	6
Neuronal proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Macrophage colony-stimulating factor 1 receptor	0	3	4	7
Proto-oncogene tyrosine-protein kinase ROS	0	1	4	5
Tyrosine-protein kinase Fgr	0	0	6	6
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	4	4
Uncharacterized serine/threonine-protein kinase SBK3	0	0	4	4
Mast/stem cell growth factor receptor Kit	0	4	5	9
Cytochrome P450 2A6	0	2	0	2
Myosin light chain kinase, smooth muscle	0	0	4	4
Angiotensin-converting enzyme	0	2	0	2
Insulin receptor-related protein	0	0	4	4
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Platelet-derived growth factor receptor alpha	0	5	5	10
Tyrosine-protein kinase Blk	0	1	0	1
Vascular endothelial growth factor receptor 1	0	1	4	5
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	4	4
Serine/threonine-protein kinase MAK	0	0	4	4
Cytochrome P450 2B6	0	3	0	3
Cyclin-dependent kinase 11B	0	0	4	4
Fibroblast growth factor receptor 2	0	0	4	4
Receptor tyrosine-protein kinase erbB-3	0	0	4	4
Fibroblast growth factor receptor 4	0	0	4	4
Fibroblast growth factor receptor 3	0	0	4	4
Ribosomal protein S6 kinase beta-1	0	1	6	7
Protein kinase C eta type	0	2	4	6
Activin receptor type-2A	0	0	4	4
Ephrin type-A receptor 3	0	0	4	4
Ephrin type-A receptor 8	0	0	4	4
Leukocyte tyrosine kinase receptor	0	0	4	4
Tyrosine-protein kinase receptor UFO	0	0	4	4
Mitogen-activated protein kinase 4	0	0	4	4
G protein-coupled receptor kinase 4	0	0	4	4
Tyrosine-protein kinase receptor Tie-1	0	0	4	4
Vascular endothelial growth factor receptor 3	0	1	4	5
Vascular endothelial growth factor receptor 2	0	5	5	11
Serine/threonine-protein kinase receptor R3	0	0	5	5
Megakaryocyte-associated tyrosine-protein kinase	0	0	4	4
Tyrosine-protein kinase TXK	0	2	4	6
G protein-coupled receptor kinase 6	0	0	5	5
Tyrosine-protein kinase ZAP-70	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 4	0	0	5	5
Cyclin-dependent kinase 8	0	1	4	5
Dual specificity protein kinase CLK3	0	0	5	5
Tyrosine-protein kinase Blk	0	2	4	6
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Cytoplasmic tyrosine-protein kinase BMX	0	1	4	5
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	4	4
Serine/threonine-protein kinase Nek4	0	0	4	4
Serine/threonine-protein kinase PLK1	0	2	6	8
Mitogen-activated protein kinase 12	0	2	4	6
Mitogen-activated protein kinase 10	0	0	6	6
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	4	5
Ephrin type-B receptor 1	0	0	4	4
Hormonally up-regulated neu tumor-associated kinase	0	0	4	4
Serine/threonine-protein kinase SIK1	0	2	4	6
Receptor-interacting serine/threonine-protein kinase 4	0	0	4	4
Cell division control protein 2 homolog	0	0	4	4
Calcium-dependent protein kinase 1	0	0	4	4
Tubulin alpha-1A chain	0	0	4	4
Casein kinase II subunit alpha	0	1	4	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	4	4
SRSF protein kinase 2	0	0	4	4
Casein kinase I isoform gamma-2	0	0	6	6
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Mitogen-activated protein kinase kinase kinase 9	0	0	4	4
Serine/threonine-protein kinase PknB	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	4	4
Myelin transcription factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Protein kinase C epsilon type	0	2	4	6
Angiopoietin-1 receptor	0	1	4	5
Mitogen-activated protein kinase kinase kinase 10	0	0	4	4
Tyrosine-protein kinase receptor TYRO3	0	0	4	4
Cyclin-dependent kinase 18	0	0	5	5
Tyrosine-protein kinase ITK/TSK	0	2	4	6
Myotonin-protein kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 12	0	0	4	4
Tyrosine-protein kinase Mer	0	2	6	8
Serine/threonine-protein kinase PAK 1	0	0	4	4
cGMP-dependent protein kinase 2	0	0	4	4
Serine/threonine-protein kinase PRP4 homolog	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 1	0	1	4	5
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	4	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Calcium/calmodulin-dependent protein kinase type 1	0	0	4	4
Sodium channel protein type 5 subunit alpha	0	4	0	4
Serine/threonine-protein kinase D1	0	2	4	6
Receptor tyrosine-protein kinase erbB-4	0	2	4	6
Ribosomal protein S6 kinase alpha-2	0	0	4	4
Rhodopsin kinase GRK1	0	0	4	4
NT-3 growth factor receptor	0	0	4	4
BDNF/NT-3 growth factors receptor	0	0	4	4
Mitogen-activated protein kinase 6	0	0	4	4
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	4	4
Serine/threonine-protein kinase SBK1	0	0	4	4
Mitogen-activated protein kinase kinase kinase 19	0	0	4	4
Serine/threonine-protein kinase TNNI3K	0	1	4	5
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	4	4
Serine/threonine-protein kinase Nek5	0	0	4	4
Breakpoint cluster region protein	0	1	0	1
Dual serine/threonine and tyrosine protein kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 15	0	0	4	4
Serine/threonine-protein kinase tousled-like 2	0	0	4	4
Serine/threonine-protein kinase 32C	0	0	4	4
Serine/threonine-protein kinase pim-3	0	0	4	4
Serine/threonine-protein kinase VRK2	0	0	4	4
Myosin light chain kinase family member 4	0	0	4	4
Homeodomain-interacting protein kinase 1	0	1	4	5
Calcium/calmodulin-dependent protein kinase type 1D	0	0	4	4
Cyclin-dependent kinase-like 3	0	0	4	4
Serine/threonine-protein kinase BRSK2	0	0	4	4
Serine/threonine-protein kinase NIM1	0	0	4	4
Serine/threonine-protein kinase ULK2	0	0	4	4
Serine/threonine-protein kinase DCLK2	0	0	4	4
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	4	4
Casein kinase I isoform alpha-like	0	0	4	4
Homeodomain-interacting protein kinase 4	0	1	4	5
Myosin-IIIa	0	0	4	4
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	4	4
Serine/threonine-protein kinase Nek11	0	0	4	4
Serine/threonine-protein kinase BRSK1	0	0	4	4
Serine/threonine-protein kinase 35	0	0	4	4
Serine/threonine-protein kinase Nek7	0	0	5	5
Rhodopsin kinase GRK7	0	0	4	4
Serine/threonine-protein kinase 32A	0	0	4	4
Myosin-IIIb	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	4	4
Cyclin-dependent kinase-like 2	0	0	4	4
Serine/threonine-protein kinase Sgk3	0	0	4	4
Atypical kinase COQ8B, mitochondrial	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1G	0	0	5	5
Cyclin-dependent kinase 15	0	0	4	4
PAS domain-containing serine/threonine-protein kinase	0	0	5	5
Dual specificity testis-specific protein kinase 2	0	0	5	5
SRSF protein kinase 1	0	0	4	4
Protein cereblon	0	6	1	8
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	4	4
Serine/threonine-protein kinase RIO1	0	0	4	4
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase RIO2	0	0	4	4
Cyclin-dependent kinase 19	0	1	4	5
Transient receptor potential cation channel subfamily M member 6	0	0	4	4
Testis-specific serine/threonine-protein kinase 1	0	0	4	4
Serine/threonine-protein kinase 33	0	0	4	4
Serine/threonine-protein kinase DCLK3	0	0	4	4
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	4	4
Homeodomain-interacting protein kinase 2	0	1	4	5
Tyrosine-protein kinase Srms	0	0	4	4
Homeodomain-interacting protein kinase 3	0	1	4	5
Serine/threonine-protein kinase PLK3	0	1	4	5
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	4	5
Serine/threonine-protein kinase Nek6	0	0	4	4
SNF-related serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase LATS2	0	0	4	4
Serine/threonine-protein kinase 36	0	0	4	4
Serine/threonine-protein kinase 32B	0	0	4	4
Serine/threonine-protein kinase PLK2	0	1	4	5
Serine/threonine-protein kinase MARK1	0	0	4	4
Serine/threonine-protein kinase pim-2	0	0	5	5
Serine/threonine-protein kinase PAK 5	0	0	4	4
eIF-2-alpha kinase GCN2	0	0	4	4
Phosphatidylinositol 4-kinase beta	0	0	4	4
Serine/threonine-protein kinase 17A	0	0	4	4
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	4	4
Ephrin type-A receptor 6	0	0	4	4
Death-associated protein kinase 2	0	0	4	4
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Serine/threonine-protein kinase tousled-like 1	0	0	4	4
ALK tyrosine kinase receptor	0	0	4	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	10	1	14
SRSF protein kinase 3	0	0	4	4
Cyclin-dependent kinase 11A	0	0	4	4
Aurora kinase C	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	4	4
Microtubule-associated serine/threonine-protein kinase 1	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	6	6
NF-kappa-B essential modulator	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	8	0	0	8
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	2	2	1	5
Glutamate receptor 3	2	2	1	5
Glutamate receptor 4	2	2	1	5
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	4	0	6
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
Chain A, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Chain A, Dutpase	0	0	1	1
Chain B, Dutpase	0	0	1	1
Thymidine phosphorylase	0	0	0	3
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	2	0	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	6	0	0	6
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	2
5-hydroxytryptamine receptor 7	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Vpr	4	0	0	4
Glutathione S-transferase omega-1	0	1	0	1
TAR DNA-binding protein 43	6	1	0	7
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier family 22 member 7	0	0	0	3
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Serum paraoxonase/arylesterase 1	0	6	0	6
Kinesin-like protein KIF11	0	1	0	1
Nucleotide-binding oligomerization domain-containing protein 2	0	2	0	2
importin subunit beta-1 isoform 1	7	0	0	7
snurportin-1	7	0	0	7
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Thymidylate kinase	0	2	0	2
Uridine phosphorylase 1	0	0	0	1
Eyes absent homolog 2	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	2
Protein kinase C gamma type	0	2	0	2
Substance-P receptor	0	2	1	3
Substance-P receptor	0	0	1	1
Ornithine decarboxylase	1	1	0	2
Mitochondrial 2-oxodicarboxylate carrier	0	1	0	1
NS5	0	0	1	1
Parkin	5	0	0	5
Glucose transporter	0	1	0	1
Serine hydrolase RBBP9	0	1	0	1
Hexose transporter 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	2
Endothelial PAS domain-containing protein 1	0	1	0	2
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
ubiquitin-conjugating enzyme E2 N	0	2	0	2
protein AF-9 isoform a	0	0	0	3
Estrogen receptor	0	7	1	9
Substance-K receptor	0	10	0	10
C-8 sterol isomerase	0	2	0	2
Alpha-synuclein	5	2	0	7
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	3	1	4
Genome polyprotein	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	1	0	3
Regulatory protein E2	0	0	2	2
DNA topoisomerase 2	0	0	0	2
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	10	0	11
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	0	0	1
Sphingosine kinase 1	0	0	0	1
interferon gamma precursor	0	0	0	4
Sodium/nucleoside cotransporter 2	0	3	0	3
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
nonstructural protein 1	4	0	0	4
Solute carrier family 22 member 8	0	1	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
Albumin	0	3	2	9
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Equilibrative nucleoside transporter 1	0	3	0	3
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Excitatory amino acid transporter 4	0	1	0	1
Glutathione reductase, mitochondrial	0	5	0	6
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	3	0	3
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Chain E, Fibrin beta chain	0	2	0	2
Chain A, RNA-directed RNA polymerase NS5	0	2	0	2
WRN	5	0	0	5
Mcl-1	0	1	0	1
MPI protein	0	1	0	1
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0	0	0	1
alkaline phosphatase, intestinal	0	0	1	1
hypothetical protein, conserved	3	0	0	3
luciferase	2	0	0	2
pyruvate kinase	4	0	0	4
CDK5	0	0	0	1
major prion protein preproprotein Prp precursor	0	1	0	1
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	0	1	1
intestinal alkaline phosphatase precursor	0	0	1	1
Vif	0	2	0	2
Tat	0	2	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	0	2	0	2
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
endoribonuclease toxin MazF	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Pyruvate kinase PKM	0	1	0	1
phosphoglycerate kinase	6	0	0	6
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
large T antigen	0	1	0	1
Carbonic anhydrase	0	3	0	5
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Urease subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Urease subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	3
Cytochrome P450 2C8	0	1	0	2
Cytochrome P450 3A5	0	4	0	5
Adenosine receptor A2a	0	4	0	4
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Toll-like receptor 7	0	0	1	1
histone deacetylase 9 isoform 3	4	0	0	4
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	3	0	0	3
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	4	0	4
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	1
Substance-P receptor	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	5	0	0	5
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	8	0	8
Chain A, Acetylcholinesterase	0	1	0	1
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Olfactory receptor 51E2	0	1	0	1
Chain A, Epidermal growth factor receptor	0	1	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	2
Cell division cycle 7-related protein kinase	0	0	3	3
G1/S-specific cyclin-E1	0	1	0	1
Cyclin-dependent kinase 10	0	0	2	2
ATP-dependent RNA helicase DHX30	0	0	4	4
Alpha-1A adrenergic receptor	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	3	0	3
Phospholipase A-2-activating protein	0	2	0	2
dopamine D1 receptor	5	0	0	5
Alkaline phosphatase, placental type	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Carbonic anhydrase	0	0	0	2
SLC16A10 protein	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Cationic amino acid transporter 3	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	3
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
PINK1	1	0	0	1
Glucocorticoid receptor	0	11	3	19
Glycine receptor subunit alpha-1	0	10	0	10
Androgen receptor	0	9	0	9
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
Large neutral amino acids transporter small subunit 1	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Dipeptidyl peptidase 4	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
transcriptional regulator ERG isoform 3	3	0	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	3	4
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	8	4	13
Mu-type opioid receptor	0	8	4	15
Kappa-type opioid receptor	0	7	4	12
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	2	2
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	2	0	0	2
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Amine oxidase [flavin-containing] A	0	1	0	1
Alpha-1D adrenergic receptor	0	4	0	4
Cruzipain	0	1	0	1
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	2	2
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
DNA polymerase III, partial	2	0	0	2
LANA	0	0	0	1
phospholipase A2, group III	0	1	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Casein kinase II subunit beta	0	1	0	1
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Casein kinase II subunit alpha 3	0	1	0	1
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
Single-stranded DNA cytosine deaminase	2	0	0	2
P2Y purinoceptor 12	0	2	0	2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Opioid receptor, delta 1b	0	1	0	1
Acetylcholinesterase	0	3	0	3
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	0	2
Translocator protein	0	0	1	1
Proteinase-activated receptor 1	0	1	1	2
Sodium-dependent serotonin transporter	0	3	0	3
Delta-type opioid receptor	0	5	3	11
Kappa-type opioid receptor	0	5	3	10
UDP-glucuronosyltransferase 1A3	0	0	0	1
Kappa-type opioid receptor	0	7	1	10
Mu-type opioid receptor	0	5	3	12
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	6	2	9
Beta-2 adrenergic receptor	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	1	1
Mu-type opioid receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Adenosine receptor A1	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Cholinesterase	0	3	0	3
Cholinesterase	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	2
NAD-dependent protein deacetylase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	1	0	1
Signal transducer and activator of transcription 3	0	2	0	2
Signal transducer and activator of transcription 1-alpha/beta	0	1	0	1
Signal transducer and activator of transcription 1	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Integrin alpha-V	0	1	0	1
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	4	0	4
UDP-glucuronosyltransferase 2B10	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Beta-tubulin	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	1	0	2
Beta-lactamase	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
vasopressin V1b receptor	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Tumor necrosis factor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Adenosine receptor A2b	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chitotriosidase-1	0	2	1	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Endochitinase B1	0	2	1	3
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
Pirin	0	1	0	1
GTPase KRas	0	1	0	1
Serine/threonine-protein kinase B-raf	0	2	0	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Heat shock factor protein 1	0	1	0	1
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Regulatory protein E2	0	0	1	1
Regulatory protein E2	0	0	1	1
Calcium-activated potassium channel subunit alpha-1	0	1	0	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Progesterone receptor	0	4	0	5
Glucocorticoid receptor	0	2	1	3
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	3	2	5
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	5	1	6
SUMO-1	0	1	0	1
tumor susceptibility gene 101 protein	1	0	0	1
chaperonin GroEL	1	0	0	1
Exoribonuclease H	0	2	0	2
Coproheme decarboxylase	0	0	1	1
Protease	0	5	2	14
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Gag-Pol polyprotein	0	3	0	3
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	3	0	3
Gag-Pol polyprotein	0	2	0	2
Vasopressin V1a receptor	0	4	0	4
Thromboxane-A synthase	0	0	0	2
Plasmepsin V	0	1	0	1
Protease	0	4	2	6
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Chain A, Protease	0	0	1	1
Chain B, Protease	0	0	1	1
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Genome polyprotein	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
BRCA1	1	0	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
melanocortin receptor 4	0	1	1	2
Platelet-derived growth factor receptor beta	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Cyclin-C	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Protein delta homolog 1	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	2	0	2
Splicing factor 3B subunit 3	0	1	0	1
Chain A, CES1 protein	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
D(4) dopamine receptor	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase	0	1	0	1
Chain A, Tyrosine-protein kinase JAK2	0	1	0	1
Serine/threonine-protein kinase Sgk1	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Tyrosine-protein kinase JAK2	0	1	0	1
Tyrosine-protein kinase JAK3	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Chain A, Cytidine Deaminase	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Equilibrative nucleoside transporter 2	0	2	0	2
Uridine-cytidine kinase 1	0	0	0	1
Solute carrier family 28 member 3	0	2	0	2
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(6)

Research Excerpts

Overview

Context

Treatment

Research

Studies (966)

Protein Targets (1,879)

Anal Cancer

Synonyms(6)

Research Excerpts

Overview

Context

Treatment

Research

Studies (966)

Drugs Studied (252)

Protein Targets (1,879)