An agent that inhibits sodium influx through cell membranes.
| Member | Definition | Class |
|---|
| 10-hydroxycarbamazepine | A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine. | licarbazepine |
| 5-(n,n-hexamethylene)amiloride | A member of the class of pyrazines that is amiloride in which the two amino hydrogens at position N-5 are replaced by a hexamethylene moiety, resulting in the formation of an azepane ring. | 5-(N,N-hexamethylene)amiloride |
| amiloride | A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid. | amiloride |
| amiloride hydrochloride | A hydrate that is the dihydrate of amiloride hydrochloride. | amiloride hydrochloride dihydrate |
| amiloride hydrochloride, anhydrous | A hydrochloride obtained by combining amiloride with one molar equivalent of hydrochloric acid. | amiloride hydrochloride |
| carbamazepine | A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant. | carbamazepine |
| cocaine | A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca. | cocaine |
| diazoxide | A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies. | diazoxide |
| encainide | 4-Methoxy-N-phenylbenzamide in which the hydrogen at the 2 position of the phenyl group is substituted by a 2-(1-methylpiperidin-2-yl)ethyl group. A class Ic antiarrhythmic, the hydrochloride was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market. | encainide |
| ethylisopropylamiloride | A member of the class of pyrazines that is amiloride in which the amino substitutent of the pyrazine ring that is adjacent to the chloro substituent has been substituted by an ethyl group and by an isopropyl group. | ethylisopropylamiloride |
| evans blue | An organic sodium salt that is the tetrasodium salt of 6,6'-{(3,3'-dimethyl[1,1'-biphenyl]-4,4'-diyl)bis[diazene-2,1-diyl]}bis(4-amino-5-hydroxynaphthalene-1,3-disulfonate). It is sometimes used as a counterstain, especially in fluorescent methods to suppress background autofluorescence. | Evans blue |
| phenytoin | A imidazolidine-2,4-dione that consists of hydantoin bearing two phenyl substituents at position 5. | phenytoin |
| pilsicainide | A secondary carboxamide resulting from the formal condensation of the amino group of 2,6-dimethylaniline with the carboxy group of (tetrahydro-1H-pyrrolizin-7a(5H)-yl)acetic acid. It is a sodium channel blocker which is used as an antiarrhythmic drug for the management of atrial tachyarrhythmias in Japan. | pilsicainide |
| procainamide | A benzamide that is 4-aminobenzamide substituted on the amide N by a 2-(diethylamino)ethyl group. It is a pharmaceutical antiarrhythmic agent used for the medical treatment of cardiac arrhythmias. | procainamide |
| quinidine | A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy. | quinidine |
| saxitoxin | An alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning. | saxitoxin |
| tocainide | A monocarboxylic acid amide in which 2,6-dimethylphenylaniline and isobutyric acid have combined to form the amide bond; used as a local anaesthetic. | tocainide |
| topiramate | A hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. | topiramate |
| triamterene | Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema. | triamterene |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 15.0275 | 1 | 10 |
| 67.9K protein | Vaccinia virus | Potency | 17.2663 | 2 | 7 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 24.2913 | 2 | 8 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 24.4274 | 1 | 4 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 36.8205 | 2 | 6 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 24.3699 | 1 | 18 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 30.7525 | 5 | 18 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 10.0000 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 25.7513 | 12 | 61 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 35.0730 | 2 | 12 |
| arylsulfatase A | Homo sapiens (human) | Potency | 5.1524 | 1 | 5 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 14.6742 | 4 | 6 |
| Ataxin-2 | Homo sapiens (human) | Potency | 34.4919 | 2 | 4 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 12.7028 | 1 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 54.2440 | 2 | 5 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 8.4921 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 13.2717 | 2 | 3 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 68.9736 | 1 | 2 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 16.9893 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 68.9736 | 1 | 2 |
| Caspase-7 | Homo sapiens (human) | Potency | 12.8127 | 1 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 26.4559 | 3 | 10 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 12.5893 | 2 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 17.5284 | 1 | 9 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 37.0035 | 2 | 5 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 44.6903 | 3 | 9 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 26.1168 | 2 | 7 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 15.6134 | 2 | 15 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 21.2866 | 2 | 6 |
| Chain A, PAPAIN | Carica papaya (papaya) | Potency | 22.3872 | 1 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 19.9054 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 15.1769 | 1 | 5 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 15.6134 | 2 | 15 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 58.9586 | 2 | 5 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 15.3266 | 1 | 3 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 32.4648 | 1 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 13.8029 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 19.4784 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 24.8323 | 1 | 4 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 23.8676 | 2 | 7 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 16.6838 | 1 | 10 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 21.5150 | 2 | 3 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 100.0000 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 8.2623 | 1 | 3 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 25.7642 | 11 | 46 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 28.9272 | 3 | 9 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 37.5872 | 10 | 41 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 15.5524 | 1 | 9 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 38.1932 | 5 | 13 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 27.8723 | 1 | 4 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 13.8029 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| GALC protein | Homo sapiens (human) | Potency | 0.7079 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 22.8653 | 1 | 4 |
| geminin | Homo sapiens (human) | Potency | 8.8810 | 4 | 13 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 24.2369 | 3 | 14 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 12.2318 | 1 | 3 |
| GLS protein | Homo sapiens (human) | Potency | 24.7279 | 1 | 3 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 22.2059 | 1 | 9 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 28.1681 | 5 | 21 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 27.3060 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 7.8566 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 35.3476 | 2 | 6 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 25.8184 | 2 | 10 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 35.1981 | 2 | 8 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 40.6634 | 1 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 13.8029 | 1 | 1 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 36.2891 | 2 | 6 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 33.1443 | 3 | 3 |
| IDH1 | Homo sapiens (human) | Potency | 11.6404 | 1 | 4 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 38.5710 | 2 | 3 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 13.8029 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 9.6071 | 1 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 12.5893 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 12.5893 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 13.8029 | 1 | 1 |
| interleukin 8 | Homo sapiens (human) | Potency | 70.9011 | 1 | 2 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 1.7846 | 2 | 13 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 15.0654 | 1 | 2 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 26.0099 | 2 | 4 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 32.8332 | 3 | 10 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 57.7315 | 1 | 2 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 13.3119 | 1 | 3 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 7.2417 | 2 | 6 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 13.1999 | 1 | 5 |
| Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 33.9972 | 1 | 2 |
| Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 33.9972 | 1 | 2 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 0.2239 | 2 | 2 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 6.3096 | 1 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 2.8184 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 32.9510 | 4 | 18 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 16.3234 | 1 | 2 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 42.2395 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 36.5686 | 2 | 6 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 16.8666 | 2 | 5 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 31.4449 | 3 | 13 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 12.5893 | 1 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| Parkin | Homo sapiens (human) | Potency | 14.5810 | 1 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 10.8163 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 4.0533 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 69.4479 | 1 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 26.2052 | 5 | 14 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 27.3320 | 5 | 12 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 3.1653 | 1 | 4 |
| polyprotein | Zika virus | Potency | 35.4813 | 1 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 8.9125 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 15.8489 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 22.2009 | 1 | 7 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 40.3038 | 3 | 14 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 56.2341 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 25.9150 | 2 | 4 |
| putative alpha-glucosidase | Oryza sativa Japonica Group (Japanese rice) | Potency | 39.8107 | 1 | 1 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 17.9008 | 2 | 4 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 12.5893 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 32.5916 | 2 | 8 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 4.4668 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 7.3866 | 1 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 22.4432 | 3 | 17 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 20.8893 | 4 | 10 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 18.4930 | 2 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 30.7478 | 2 | 7 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 30.7478 | 2 | 7 |
| Smad3 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 38.5710 | 2 | 3 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 3.9811 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 3.9472 | 1 | 2 |
| TDP1 protein | Homo sapiens (human) | Potency | 17.7793 | 2 | 37 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 36.0666 | 4 | 18 |
| Thrombopoietin | Homo sapiens (human) | Potency | 17.5594 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 42.5026 | 2 | 18 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 16.2320 | 3 | 8 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 18.5037 | 2 | 18 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 8.9716 | 1 | 2 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 47.3079 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 3.1653 | 1 | 4 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 3.1653 | 1 | 4 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 69.8589 | 1 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 33.0173 | 2 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 31.1027 | 5 | 14 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 27.3060 | 1 | 1 |
| Vpr | Human immunodeficiency virus 1 | Potency | 0.8913 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 10 kDa chaperonin | Escherichia coli | IC50 | 0.0630 | 2 | 2 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | Ki | 77.6505 | 2 | 2 |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 0.0855 | 2 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | IC50 | 0.0855 | 2 | 2 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | IC50 | 0.0855 | 2 | 2 |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | IC50 | 85.4000 | 1 | 4 |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | Ki | 0.3010 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 161.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 0.0630 | 2 | 2 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 1.0000 | 2 | 2 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 1.0000 | 1 | 2 |
| Acetylcholinesterase | Bos taurus (cattle) | IC50 | 0.5000 | 1 | 1 |
| Acid-sensing ion channel 1 | Rattus norvegicus (Norway rat) | IC50 | 30.2000 | 1 | 1 |
| Acid-sensing ion channel 3 | Homo sapiens (human) | IC50 | 4.4000 | 1 | 1 |
| Adenosine receptor A2a | Homo sapiens (human) | IC50 | 2.6850 | 2 | 2 |
| Adenosine receptor A2a | Homo sapiens (human) | Ki | 8.9600 | 3 | 3 |
| Adenosine receptor A2b | Homo sapiens (human) | IC50 | 0.2700 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.7544 | 1 | 1 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.7544 | 1 | 1 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 5.7544 | 1 | 1 |
| Amiloride-sensitive sodium channel subunit alpha | Homo sapiens (human) | IC50 | 0.7760 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 3.9090 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 0.3380 | 1 | 1 |
| Arachidonate 5-lipoxygenase-activating protein | Homo sapiens (human) | Ki | 0.0009 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 6 |
| ATP-binding cassette sub-family C member 8 | Homo sapiens (human) | IC50 | 470.5000 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 49.2333 | 9 | 9 |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | IC50 | 11.5000 | 4 | 4 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 3.6240 | 5 | 5 |
| ATP-sensitive inward rectifier potassium channel 11 | Homo sapiens (human) | IC50 | 470.5000 | 4 | 4 |
| Beta-carbonic anhydrase 1 | Mycobacterium tuberculosis H37Rv | Ki | 0.6113 | 3 | 3 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 422.5333 | 4 | 15 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Homo sapiens (human) | Ki | 1.1150 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4B | Homo sapiens (human) | Ki | 1.1150 | 1 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | Homo sapiens (human) | Ki | 1.1150 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 6 |
| Carbonic anhydrase | Candida albicans SC5314 | Ki | 0.9602 | 4 | 5 |
| Carbonic anhydrase | Helicobacter pylori 26695 | Ki | 0.1885 | 2 | 2 |
| Carbonic anhydrase | Methanosarcina thermophila | Ki | 0.5700 | 2 | 2 |
| Carbonic anhydrase | Methanothermobacter thermautotrophicus str. Delta H | Ki | 23.5000 | 1 | 1 |
| Carbonic anhydrase | Saccharomyces cerevisiae S288C | Ki | 0.1100 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 0.3670 | 1 | 1 |
| Carbonic anhydrase | Anopheles gambiae (African malaria mosquito) | Ki | 100.0000 | 1 | 1 |
| Carbonic anhydrase | Astrosclera willeyana | Ki | 0.0380 | 1 | 1 |
| Carbonic anhydrase | Cryptococcus neoformans var. grubii | Ki | 0.3685 | 2 | 2 |
| Carbonic anhydrase | Mycobacterium tuberculosis H37Rv | Ki | 3.0200 | 1 | 1 |
| Carbonic anhydrase | Nakaseomyces glabratus CBS 138 | Ki | 0.1100 | 1 | 1 |
| Carbonic anhydrase | Stylophora pistillata | Ki | 0.0291 | 2 | 2 |
| Carbonic anhydrase | Sulfurihydrogenibium sp. YO3AOP1 | Ki | 0.0066 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | IC50 | 0.2500 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 8.4445 | 70 | 96 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 21.3774 | 18 | 38 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 0.0470 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 30.5338 | 6 | 26 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 23.8591 | 14 | 34 |
| Carbonic anhydrase 15 | Mus musculus (house mouse) | Ki | 0.0714 | 4 | 5 |
| Carbonic anhydrase 2 | Homo sapiens (human) | IC50 | 0.8683 | 3 | 3 |
| Carbonic anhydrase 2 | Rattus norvegicus (Norway rat) | IC50 | 1.4000 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 6.8337 | 88 | 120 |
| Carbonic anhydrase 2 | Mycobacterium tuberculosis H37Rv | Ki | 0.4740 | 1 | 1 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 244.1792 | 5 | 16 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | IC50 | 0.0540 | 1 | 1 |
| Carbonic anhydrase 4 | Bos taurus (cattle) | Ki | 0.0713 | 6 | 9 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 27.7630 | 10 | 30 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 22.5661 | 16 | 38 |
| Carbonic anhydrase 5A, mitochondrial | Mus musculus (house mouse) | Ki | 0.0930 | 1 | 4 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 22.2735 | 15 | 37 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 37.4907 | 9 | 21 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 18.9008 | 22 | 42 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 16.8509 | 29 | 51 |
| Carbonic anhydrase, alpha family | Hydrogenovibrio crunogenus XCL-2 | Ki | 0.7690 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | IC50 | 36.8000 | 1 | 1 |
| Casein kinase I isoform delta | Homo sapiens (human) | IC50 | 31.6000 | 1 | 2 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | IC50 | 31.6000 | 1 | 2 |
| Caspase-1 | Homo sapiens (human) | IC50 | 3.6630 | 1 | 1 |
| Cathepsin G | Homo sapiens (human) | IC50 | 7.4130 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | Ki | 345.7667 | 1 | 3 |
| Chain A, Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 0.2500 | 1 | 1 |
| Chain A, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | Homo sapiens (human) | Ki | 5.3000 | 1 | 2 |
| Chain U, UROKINASE-TYPE PLASMINOGEN ACTIVATOR | Homo sapiens (human) | Ki | 5.3000 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 7.3700 | 1 | 1 |
| Cholinesterase | Homo sapiens (human) | IC50 | 1.2300 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 740.0000 | 1 | 1 |
| Coagulation factor X | Homo sapiens (human) | IC50 | 50.0000 | 2 | 2 |
| Coagulation factor XI | Homo sapiens (human) | IC50 | 50.0000 | 2 | 2 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 210.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | Ki | 0.0300 | 1 | 1 |
| Cytochrome P450 2C8 | Homo sapiens (human) | Ki | 0.0100 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 16.0000 | 2 | 3 |
| Cytochrome P450 2D1 | Rattus norvegicus (Norway rat) | IC50 | 19.9000 | 1 | 1 |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | IC50 | 2.8000 | 1 | 1 |
| Cytochrome P450 2D3 | Rattus norvegicus (Norway rat) | IC50 | 26.9000 | 1 | 1 |
| Cytochrome P450 2D4 | Rattus norvegicus (Norway rat) | IC50 | 47.2000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 2.3605 | 46 | 46 |
| Cytochrome P450 2D6 | Homo sapiens (human) | Ki | 0.0357 | 4 | 4 |
| Cytochrome P450 2J2 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 39.0000 | 2 | 2 |
| Cytochrome P450 3A4 | Homo sapiens (human) | Ki | 0.0100 | 1 | 1 |
| D | Rattus norvegicus (Norway rat) | IC50 | 5.7544 | 1 | 1 |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | Ki | 0.1800 | 2 | 2 |
| Delta carbonic anhydrase | Conticribra weissflogii | Ki | 0.3920 | 1 | 1 |
| Delta-type opioid receptor | Mus musculus (house mouse) | Ki | 0.1300 | 2 | 2 |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.0177 | 2 | 2 |
| Dihydrofolate reductase | Bos taurus (cattle) | IC50 | 100.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 3-like | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 3A | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | Homo sapiens (human) | IC50 | 0.9220 | 1 | 1 |
| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | Homo sapiens (human) | Ki | 0.8240 | 1 | 1 |
| Estrogen receptor | Mus musculus (house mouse) | IC50 | 6.8848 | 1 | 1 |
| Estrogen receptor beta | Mus musculus (house mouse) | IC50 | 6.8848 | 1 | 1 |
| Fatty acid-binding protein, heart | Homo sapiens (human) | IC50 | 0.3670 | 1 | 1 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | IC50 | 210.0000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | IC50 | 127.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 100.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Mus musculus (house mouse) | Ki | 155.0000 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 5.0150 | 2 | 2 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 325.0000 | 1 | 1 |
| Janus kinase 2 (a protein tyrosine kinase) | Homo sapiens (human) | IC50 | 4.6130 | 1 | 1 |
| Leukotriene B4 receptor 1 | Homo sapiens (human) | Ki | 0.5240 | 1 | 1 |
| Leukotriene B4 receptor 2 | Homo sapiens (human) | Ki | 0.5240 | 1 | 1 |
| Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | IC50 | 11.0400 | 5 | 5 |
| Lysosomal Pro-X carboxypeptidase | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Membrane primary amine oxidase | Rattus norvegicus (Norway rat) | Ki | 10.0000 | 1 | 1 |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | Ki | 0.0100 | 1 | 1 |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | Ki | 0.2500 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 11.2000 | 1 | 1 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 118.4667 | 1 | 6 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Ki | 61.3985 | 2 | 2 |
| Muscarinic acetylcholine receptor M2 | Sus scrofa (pig) | Ki | 0.2344 | 1 | 1 |
| Muscarinic receptor M1 | Bos taurus (cattle) | IC50 | 6.8848 | 1 | 2 |
| Neuronal acetylcholine receptor subunit alpha-7 | Rattus norvegicus (Norway rat) | Ki | 1.4600 | 1 | 1 |
| P2X purinoceptor 4 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 2 |
| Plasma kallikrein | Homo sapiens (human) | IC50 | 50.0000 | 2 | 2 |
| Plasminogen | Homo sapiens (human) | IC50 | 72.9950 | 4 | 4 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Ki | 0.0009 | 1 | 1 |
| Potassium voltage-gated channel subfamily A member 5 | Homo sapiens (human) | IC50 | 7.3000 | 1 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | Rattus norvegicus (Norway rat) | IC50 | 2.2000 | 1 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 51.0473 | 13 | 21 |
| Prolyl endopeptidase | Rattus norvegicus (Norway rat) | Ki | 0.0630 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | IC50 | 93.3333 | 3 | 3 |
| Pteridine reductase 1 | Leishmania major | Ki | 3.4000 | 1 | 1 |
| serine/threonine-protein kinase D1 isoform 2 | Homo sapiens (human) | IC50 | 6.8848 | 1 | 1 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 6.6290 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | IC50 | 1.0500 | 1 | 2 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Ki | 8.8300 | 1 | 1 |
| Sodium channel protein type 1 subunit alpha | Homo sapiens (human) | IC50 | 9.2512 | 2 | 2 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 167.0000 | 1 | 2 |
| Sodium channel protein type 10 subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sodium channel protein type 11 subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | IC50 | 54.6252 | 4 | 4 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 95.3333 | 3 | 6 |
| Sodium channel protein type 3 subunit alpha | Homo sapiens (human) | IC50 | 9.2565 | 2 | 2 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 167.0000 | 1 | 2 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 0.0104 | 2 | 2 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | Ki | 38.0000 | 1 | 2 |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | IC50 | 33.2443 | 6 | 7 |
| Sodium channel protein type 7 subunit alpha | Homo sapiens (human) | IC50 | 0.4100 | 1 | 1 |
| Sodium channel protein type 8 subunit alpha | Homo sapiens (human) | IC50 | 0.0011 | 1 | 1 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 30.8510 | 4 | 4 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | Ki | 32.7000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | IC50 | 0.2000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 1.3496 | 47 | 67 |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | Ki | 0.8500 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | Ki | 25.8768 | 25 | 40 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | IC50 | 0.3796 | 34 | 34 |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | Ki | 0.4281 | 30 | 33 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | IC50 | 1.2861 | 22 | 22 |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | Ki | 1.6163 | 30 | 32 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | IC50 | 0.5442 | 23 | 23 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 0.8885 | 15 | 18 |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | Ki | 0.3792 | 31 | 34 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.5521 | 18 | 27 |
| Sodium/hydrogen exchanger | Amphiuma tridactylum (three-toed salamander) | IC50 | 53.3500 | 1 | 2 |
| Sodium/hydrogen exchanger 1 | Homo sapiens (human) | IC50 | 42.5100 | 2 | 3 |
| Sodium/hydrogen exchanger 1 | Oryctolagus cuniculus (rabbit) | IC50 | 0.0200 | 1 | 1 |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | IC50 | 0.5050 | 1 | 2 |
| Sodium/hydrogen exchanger 1 | Oryctolagus cuniculus (rabbit) | Ki | 0.0200 | 2 | 2 |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | Ki | 0.3410 | 2 | 6 |
| Sodium/hydrogen exchanger 2 | Oryctolagus cuniculus (rabbit) | IC50 | 0.7500 | 1 | 2 |
| Sodium/hydrogen exchanger 2 | Oryctolagus cuniculus (rabbit) | Ki | 0.7500 | 2 | 4 |
| Sodium/hydrogen exchanger 2 | Rattus norvegicus (Norway rat) | Ki | 0.0800 | 2 | 2 |
| Sodium/hydrogen exchanger 3 | Rattus norvegicus (Norway rat) | IC50 | 51.2000 | 1 | 2 |
| Sodium/hydrogen exchanger 3 | Rattus norvegicus (Norway rat) | Ki | 34.9333 | 2 | 6 |
| Sodium/hydrogen exchanger 5 | Homo sapiens (human) | IC50 | 10.7100 | 1 | 2 |
| Sodium/hydrogen exchanger 5 | Homo sapiens (human) | Ki | 7.2633 | 2 | 6 |
| Solute carrier family 22 member 1 | Mus musculus (house mouse) | IC50 | 3.9000 | 1 | 1 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | IC50 | 9.8500 | 4 | 4 |
| Solute carrier family 22 member 1 | Rattus norvegicus (Norway rat) | Ki | 17.5000 | 4 | 5 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | IC50 | 64.7333 | 2 | 3 |
| Solute carrier family 22 member 1 | Homo sapiens (human) | Ki | 45.7000 | 1 | 2 |
| Solute carrier family 22 member 2 | Mus musculus (house mouse) | IC50 | 312.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | IC50 | 186.3200 | 4 | 5 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | Ki | 50.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Rattus norvegicus (Norway rat) | Ki | 19.9333 | 2 | 3 |
| Solute carrier family 22 member 3 | Homo sapiens (human) | Ki | 738.0000 | 1 | 1 |
| Solute carrier family 22 member 4 | Rattus norvegicus (Norway rat) | IC50 | 1,000.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A1 | Rattus norvegicus (Norway rat) | Ki | 9.2700 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A4 | Rattus norvegicus (Norway rat) | Ki | 120.0000 | 1 | 1 |
| Sterol O-acyltransferase 1 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Sterol O-acyltransferase 1 | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 8.7000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 740.0000 | 1 | 1 |
| Tissue-type plasminogen activator | Homo sapiens (human) | IC50 | 125.0000 | 4 | 4 |
| Tissue-type plasminogen activator | Homo sapiens (human) | Ki | 345.7667 | 1 | 3 |
| Transporter | Rattus norvegicus (Norway rat) | IC50 | 3.2277 | 13 | 15 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 2.3643 | 15 | 18 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | Ki | 0.4900 | 1 | 1 |
| Tyrosine-protein phosphatase 1 | Saccharomyces cerevisiae S288C | IC50 | 1.2000 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 1.3000 | 1 | 1 |
| UDP-glucuronosyltransferase 1-6 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 1A4 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 2B10 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| UDP-glucuronosyltransferase 2B7 | Homo sapiens (human) | IC50 | 273.2000 | 1 | 5 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 18.8975 | 8 | 8 |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | IC50 | 2.3000 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | Ki | 118.2890 | 6 | 9 |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | Ki | 5.8105 | 1 | 2 |
| Vesicular glutamate transporter 3 | Rattus norvegicus (Norway rat) | Ki | 0.0400 | 1 | 1 |
| Vitamin K-dependent protein C | Homo sapiens (human) | IC50 | 50.0000 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Cavia porcellus (domestic guinea pig) | IC50 | 70.8000 | 2 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Homo sapiens (human) | IC50 | 112.5240 | 5 | 5 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Homo sapiens (human) | IC50 | 139.2667 | 3 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | Homo sapiens (human) | IC50 | 139.2667 | 3 | 3 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Homo sapiens (human) | IC50 | 139.2667 | 3 | 3 |