An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.
Excerpt | Reference |
"If pruritus is a major symptom, topical corticosteroids should be alternated with the progesterone preparation in order to obtain maximum results." | ( Jasionowski, EA; Jasionowski, PA, 1979) |
"Pruritus is a common problem that can result from many conditions." | ( Phillips, WG, 1992) |
"This pruritus is often intractable and resistant to conventional treatment." | ( Borgeat, A; Huber, O; Mentha, G; Wilder-Smith, O, 1992) |
"Pruritus is a significant problem for many patients undergoing long-term hemodialysis." | ( Blumsack, RF; Breneman, DL; Cardone, JS; Lather, RM; Pollack, VE; Searle, EA, 1992) |
"Pruritus is a frequent symptom in chronic cholestatic liver disease." | ( Gittlen, SD; Maddrey, WC; Schulman, ES, 1990) |
"Pruritus is a common symptom among patients undergoing long-term hemodialysis." | ( Bousquet, J; Maheut, M; Michel, FB; Mion, C; Rivory, JP, 1989) |
"Persistent pruritus is one of the most common symptoms in hemodialysis patients." | ( Kuze, M; Sanada, S; Yoshida, O, 1987) |
"Aquagenic pruritus is a disease in which itchy prickling skin discomfort is evoked by contact with water at any temperature without observable cutaneous lesions." | ( Brunetti, L; Fabbri, P; Greaves, MW; Lotti, T; Panconesi, E; Steinman, HK, 1986) |
"Aquagenic pruritus is now a well-recognized symptom complex, usually of unknown origin." | ( Greaves, MW; Kligman, AM; Steinman, H, 1986) |
"Pruritus is a frequent and troublesome consequence of end-stage renal disease." | ( Blachley, JD; Blankenship, DM; Knochel, JP; Menter, A; Parker, TF, 1985) |
"Pruritus is found in 10,5 p." | ( Barbet, M; Baviera, A; Daniel, F; Foix, C; Ménard, J; Plouin, F; Schwebig, A, 1983) |
"Intense pruritus is treated by antihistamines (possibly also H2-antagonists)." | ( Braun-Falco, O; Ring, J, 1984) |
"Aquagenic pruritus is probably common, but it is generally unrecognised and may be misdiagnosed." | ( Black, AK; Coutts, A; Eady, RA; Greaves, MW, 1981) |
"Aquagenic pruritus is characterized by pruritus after contact with water; there are no objective cutaneous changes." | ( Lotti, T; Teofoli, P; Tsampau, D, 1994) |
"Pruritus is a predominant and serious phenomenon of various skin diseases." | ( Kietzmann, M, 1995) |
"Pruritus is a very common complication in chronic hemodialysis (HD) patients, however the exact mechanism for this affliction is still not known." | ( Fujimi, S; Fujishima, M; Hirakata, E; Hirakata, H; Kanai, H; Nagashima, A; Okuda, S, 1995) |
"Pruritus is a major clinical problem in patients with polycythaemia vera (PV)." | ( de Wolf, JT; Egger, R; Halie, MR; Huijgens, PC; Muller, EW; Vellenga, E; Wijermans, PW, 1995) |
"Persistent pruritus is the most common symptom in hemodialysis patients." | ( Hamada, M; Hasegawa, M; Ida, M; Matsui, C; Morohashi, M, 1994) |
"Pruritus is a severe and troublesome symptom in patients with cholestasis and is often difficult to treat." | ( Borgeat, A; Mentha, G; Savioz, D; Wilder-Smith, OH, 1994) |
"Generalized pruritus is a well-known, distressing symptom of various diseases, especially in hepatic cholestasis and chronic renal insufficiency." | ( Ramadori, G; Schwörer, H, 1993) |
"Pruritus is a common side effect of epidural and intrathecal morphine administration in humans." | ( Dubner, R; Iwata, K; Kenshalo, DR; Thomas, DA; Williams, GM, 1993) |
"Pruritus is a severe and troublesome symptom in patients with cholestasis and is often difficult to treat." | ( Borgeat, A; Mentha, G; Wilder-Smith, OH, 1993) |
"Pruritus is a common symptom in uraemic patients and its aetiology is poorly understood, although several factors have been implicated, including high histamine plasma levels." | ( De Filippi, C; Galli, F; Piazza, V; Pisati, P; Regazzini, R; Sacchi, S; Salvadeo, A, 1995) |
"Severe pruritus is frequently associated with myeloproliferative and other systemic illnesses, and often fails to respond to conventional measures." | ( Ahn, YS; Brown, H; Horstman, LL; Kolodny, L; Sevin, BU, 1996) |
"Pruritus is a significant symptom among patients receiving hemodialysis." | ( Cho, YL; Huang, TP; Liu, HN; Tarng, DC, 1996) |
"Pruritus is a common side effect associated with intrathecal morphine." | ( Arai, L; Dorsey, A; Schwartz, R; Stayer, S, 1996) |
"Pruritus is a common opioid side effect and can be so severe that opioid therapy must be modified or abandoned." | ( Dunteman, E; Filos, KS; Karanikolas, M, 1996) |
"Uraemic pruritus is a frequent and disabling symptom in patients on dialysis." | ( Fischer, FP; Kiefer, T; Kuhlmann, U; Mettang, T; Rettenmeier, AW; Thomas, S; Wodarz, R, 1996) |
"Pruritus is a common symptom among patients undergoing long-term hemodialysis." | ( Friga, V; Linos, A; Linos, DA, 1997) |
"Uremic pruritus is not related to PTH." | ( Cho, YL; Huang, TP; Liu, HN; Tarng, DC, 1997) |
"Pruritus is an unpleasant, vexing sensation that provokes an intense desire to scratch." | ( Albanesi, T; Deabate, MC; Salomone, M; Torazza, MC; Triolo, G; Zina, A, 1997) |
"Pruritus is a common and bothersome side effect of neuraxial opioids after cesarean section." | ( Beilin, Y; Bernstein, HH; Zahn, J; Zenzen, WJ; Zucker-Pinchoff, B, 1998) |
"The causes of pruritus are numerous including xerosis, drug and photoeruptions, follicular and papular eruptions as well as infestations and infections by a wide range of organisms." | ( Lee, RB; Skelton, HG; Smith, KJ; Wagner, KF; Yeager, J, 1997) |
"Pruritus is a common, unpleasant symptom of uremic patients." | ( Balaskas, EV; Bamihas, GI; Karamouzis, M; Tourkantonis, A; Voyiatzis, G, 1998) |
"Pruritus is a frequent, distressing and sometimes disabling symptom of liver and biliary tract disorders." | ( Engelkens, HJ; van Buuren, HR; Wolfhagen, FH, 1998) |
"Pruritus is a common symptom in cholestatic liver disease but is rare in chronic hepatitis C." | ( Bergasa, NV; Chia, SC; Di Bisceglie, AM; Goodman, Z; Hoofnagle, JH; Kleiner, DE, 1998) |
"Severe generalized pruritus is a common drawback in chloroquine therapy of malaria in black Africans." | ( Ajayi, AA; Olotu, TC; Sofowora, GG, 1998) |
"Pruritus is a frequent complication (40%-100%) of intrathecal (IT) fentanyl 25 microg (F) for labor analgesia." | ( Asokumar, B; Ivankovich, AD; McCarthy, RJ; Newman, LM; Tuman, KJ, 1998) |
"Pruritus is often considered a common but minor symptom of pregnancy." | ( Clark, TJ; Dwarakanath, L; Weaver, JB, 1999) |
"The perception of pruritus is modified by endogenous opiates via central opiate receptors in a histamine-independent manner." | ( Beissert, S; Luger, T; Metze, D; Reimann, S, 1999) |
"Pruritus is a relatively rare symptom in malignancies, but may be worse than pain." | ( Krajnik, M; Zylicz, Z, 1999) |
"Pruritus is a distressing symptom affecting up to 90% of dialysis patients." | ( Ashmore, SD; Chrystyn, H; Daly, MJ; Jones, CH; Newstead, CG, 2000) |
"Pruritus is a common side effect of intrathecal morphine injection for postoperative pain control." | ( Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM, 2000) |
"Pruritus is experienced by about 80% of patients with primary biliary cirrhosis." | ( Bergasa, NV; Jones, EA; Mehlman, JK, 2000) |
"Aquagenic pruritus is a rare but distinct entity in which intense itching develops after contact with water, in the absence of cutaneous signs or underlying disorders that could explain the symptoms." | ( Anstey, AV; Holme, SA, 2001) |
"Vulvar pruritus is a common complaint in females of all ages." | ( Mallory, SB; Merritt, DF; Paek, SC, 2001) |
"Pruritus is prevalent in 5-12% of palliative care patients." | ( Fulfaro, F; Mercadante, S; Villari, P, 2001) |
"Recalcitrant pruritus is a hallmark of lichen simplex, a localized variant of atopic dermatitis." | ( Brunner, B; Heckmann, M; Heyer, G; Plewig, G, 2002) |
"Although pruritus is common in scalp skin, the forearm has been the main site for investigation in previous experimental studies." | ( McGlone, F; Rukwied, R; Schmelz, M; Zeck, S, 2002) |
"Water-induced pruritus is characterized by the development of intense and widespread itching after contact with water at any temperature and without observable skin lesions." | ( Aragüés, M; Córdoba, S; Daudén, E; García-Díez, A; Hernández-Núñez, A, 2001) |
"Uremic pruritus is one of the most bothersome symptoms in patients with chronic renal failure." | ( Kusztal, M; Magott, M; Salomon, J; Sikora, M; Szepietowski, JC; Szepietowski, T, 2002) |
"Pruritus is a common symptom among patients on haemodialysis (HD)." | ( Bonadonna, A; La Milia, V; Virga, G; Visentin, I, 2002) |
"Pruritus is a commonly reported side effect after intrathecal fentanyl administration during spinal anesthesia." | ( Gürkan, Y; Toker, K, 2002) |
"Pruritus is a relatively rare but distressing symptom associated with cholestasis, renal failure, and malignancies." | ( Andresen, S; Davis, MP; Frandsen, JL; Taylor, S; Walsh, D, 2003) |
"Pruritus is often the most troublesome symptom in patients with chronic liver disease, particularly when cholestasis is a prominent feature." | ( Burroughs, AK; Mancuso, A; Mela, M, 2003) |
"Itch, also known as pruritus, is the major symptom in skin diseases with a variety of etiologies and pathophysiologies." | ( Fleischer, A; Yosipovitch, G, 2003) |
"Generalized pruritus is a common complication of cholestatic liver diseases, although its pathogenesis remains elusive." | ( Browning, J; Combes, B; Mayo, MJ, 2003) |
"Severe uraemic pruritus is rare, but distressing in children and can improve with ondansetron." | ( Deshpande, PV, 2004) |
"Pruritus is the most distressing symptom in haemodialysis (HD) patients." | ( Dunker, N; Gollnick, H; Röhl, FW; Weisshaar, E, 2004) |
"Nocturnal pruritus is a significant problem for patients with inflammatory skin diseases and many systemic diseases." | ( Hundley, JL; Yosipovitch, G, 2004) |
"Pruritus is one of the most common complaints among patients who visit physicians." | ( Duque, MI; Fleischer, AB; Vogel, CA; Yosipovitch, G, 2004) |
"Pruritus is a common side effect of all HES solutions, including HES 200/0." | ( Wiedermann, CJ, 2004) |
"The perception of pruritus is modified by endogenous and exogenous opioids via central opiate receptors and can be suppressed with opioid receptor antagonists." | ( Brune, A; Luger, TA; Metze, D; Ständer, S, 2004) |
"Pruritus is a distressing symptom experienced by a large proportion of patients with cholestasis." | ( Bergasa, NV; Jones, EA, 1998) |
"Uraemic pruritus is a common and distressing symptom in patients on haemodialysis for chronic renal failure." | ( Celiker, H; Gunal, AI; Gunal, SY; Kirciman, E; Ozalp, G; Yoldas, TK, 2004) |
"Severe pruritus is a frequent complication of cholestasis." | ( Krajnik, M; Stork, N; Zylicz, Z, 2005) |
"Pruritus is seen in patients suffering from anorexia nervosa and resolves on weight restoration." | ( Nielsen, PL; Serup, J; Thomsen, JS, 2005) |
"Pruritus is a frequent symptom after ITB withdrawal." | ( Ben Smail, D; Bussel, B; Denys, P; Hugeron, C, 2005) |
"Pruritus is a common and disabling symptom for patients undergoing hemodialysis." | ( Duque, MI; Fleischer, AB; Freedman, BI; Willard, J; Yosipovitch, G, 2005) |
"Its effects against pruritus are mainly attributed to its inhibition of mediator release from activated mast cells and direct antagonist effects on the released mediators which may act as local pruritogens." | ( Baolin, L; Ning, T; Weiwei, W, 2005) |
"Pruritus is a common, distressing and difficult to manage complication of many autoimmune diseases." | ( Aoki, CA; Gershwin, ME; Itoh, M; Kato, T; Kawashima, Y; Kikuchi, K; Kurokawa, T; Miyakawa, H; Nakao, K; Okano, K; Umeuchi, H, 2005) |
"Pruritus is observed in all stages and increases with the number of WBC in CSF from 30 to 55%." | ( Blum, J; Burri, C; Schmid, C, 2006) |
"Pruritus is the most common side effect of intrathecal morphine for postoperative pain relief." | ( Dimitriou, VK; Dragoumanis, CK; Iatrou, CA; Simopoulos, CE; Vogiatzaki, TD; Vretzakis, GI, 2005) |
"Uremic pruritus is a very common and frustrating condition for both patients and clinicians because no treatment has been demonstrated to be effective in relieving the itch." | ( Akai, M; Danda, Y; Gellert, R; Ide, K; Kawashima, Y; Ladefoged, SD; Mori, A; Ogasawara, M; Ueno, K; Ueno, Y; Wikström, B, 2005) |
"Pruritus is often a stressing symptom and a therapeutic challenge." | ( Degitz, K; Schuh, T; Zenker, S, 2003) |
"Uremic pruritus is still a common phenomenon in patients with end-stage renal failure, however, there is no effective treatment of choice for this condition." | ( Reich, A; Szepietowski, JC; Szepietowski, T, 2005) |
"Pain and pruritus are closely interrelated and opioids modulate both sensations." | ( Chapman, K; D'Mello, C; Le, T; Nelson, L; Swain, MG; Vergnolle, N, 2006) |
"Aquagenic pruritus is an intense prickling sensation that develops in affected individuals immediately after contact with water at any temperature." | ( Cohen, PD; Ingber, S, 2005) |
"Because pain and pruritus are clearly distinct nociceptive sensory modalities in humans, the current study evaluates the potential of ET-1 to elicit scratching behavior in mice." | ( D'Orléans-Juste, P; Fernandes, MB; Rae, GA; Trentin, PG, 2006) |
"Intractable pruritus is one of the most common symptoms of chronic liver disease, especially experienced by patients with prolonged cholestasis." | ( Berloco, PB; Corradini, SG; Iappelli, M; Lai, Q; Mennini, G; Morabito, V; Novelli, G; Novelli, L; Poli, L; Predagostini, R; Rossi, M, 2006) |
"Pruritus is a bothersome symptom affecting up to 80% of dialysis patients." | ( Chen, YC; Chiu, WT; Wu, MS, 2006) |
"Severe pruritus is a serious complication of cholestatic liver disease." | ( Athmann, C; Fliser, D; Hafer, C; Haller, H; Peter Manns, M; Rifai, K; Rosenau, J, 2006) |
"Pruritus is defined as the second order of nociception, the first being pain; thus, there is a rationale to study gabapentin, a drug that increases the threshold to experience nociception." | ( Bergasa, NV; Engler, D; Ginsburg, IH; McGee, M, 2006) |
"Uremic pruritus is a clinical phenomenon seen in patients with chronic renal failure; it provokes vigorous scratching and may lead to numerous cutaneous lesions including extensive excoriations, lichen simplex chronicus, prurigo nodularis, keratotic papules, or secondary impetigo." | ( Cohen, JB; Janniger, CK; Piela, Z; Samady, JA; Schwartz, RA; Szepietowski, JC, 1999) |
"Pruritus is the most common and distressing skin symptom, and treatment of itch is a problem for thousands of people." | ( Bigliardi, PL; Bigliardi-Qi, M; Büchner, S; Jost, G; Rufli, T; Stammer, H, 2007) |
"Pruritus is frequently the most debilitating symptom of cholestatic liver diseases." | ( Getachew, Y; Handem, I; Jacobe, H; Mayo, MJ; Rush, AJ; Saldana, S, 2007) |
"Pruritus is the most common complaint in the chronic phase, with significant effects on the patient's quality of life." | ( Bigdeli, M; Dashti-Khavidaki, S; Davoodi, SM; Khalili, H; Panahi, Y, 2007) |
"Itch (pruritus) is a sensory phenomenon characterized by a (usually) negative affective component and the initiation of a special behavioral act, i." | ( Bíró, T; Dobrosi, N; Géczy, T; Marincsák, R; Paus, R; Tóth, BI, 2007) |
"If pruritus is the most constant symptom of onchocerciasis, hanging groin is usually observed only in hyperendemic areas in association with high microfilarial density." | ( Gaulier, A; Niamba, P; Taïeb, A, 2007) |
"Pruritus is a well-known feature of chronic cholestasis in both adults and children and has been reported as the most incapacitating symptom in children with chronic liver disease." | ( Cies, JJ; Giamalis, JN, 2007) |
"Pruritus is associated with poor outcomes and a higher mortality risk, probably attributed to poor sleep quality." | ( Wikström, B, 2007) |
"Pruritus is exacerbated at night in many systemic and dermatological diseases, resulting in reports of significantly diminished quality of life and sleep disturbances." | ( Ishiuji, Y; Patel, T; Yosipovitch, G, 2007) |
"Itching, or pruritus, is defined as an unpleasant cutaneous sensation that serves as a physiological self-protective mechanism to prevent the body from being hurt by harmful external agents." | ( Chen, ZF; Sun, YG, 2007) |
"Pruritus is the most severe problem in atopic dermatitis." | ( Kambe, N; Matsuda, H; Miyachi, Y; Nakamura, Y; Tanaka, A; Tanizaki, H, 2008) |
"Pruritus is a chronic lesion in veterans that needs long-term conservation treatment." | ( Almasi, M; Davoudi, M; Peyman, M; Sadr, B; Shohrati, M, 2007) |
"Pruritus is a common problem in dialysis patients." | ( Ahmadi, F; Razeghi, E; Tavakolizadeh, S, 2008) |
"Pruritus is a common side effect." | ( English, JC; Haught, JM; Jukic, DM, 2008) |
"Pruritus is the most common side effect of intrathecal morphine." | ( Chang, FL; Ho, ST; Lee, CH; Sheen, MJ; Tsung, YC, 2008) |
"Pruritus is a frequent adverse event observed after neuraxial administration of opioids." | ( Bonnet, MP; Josserand, J; Marret, E; Mercier, FJ, 2008) |
"Pruritus is often a prominent feature and difficult to control." | ( Agarwal, R; Bhalla, A; Dheerendra, PC; Mahi, SK; Sharma, N; Singh, V, 2009) |
"Pruritus is one of the most frequent and bothersome symptoms of polycythaemia vera and other chronic myeloproliferative disorders." | ( Hasselbalch, HC; Hast, R; Hedlund, D; Kümler, T, 2008) |
"Chronic pruritus is difficult to treat and requires the evaluation of new therapeutic modalities." | ( Böckenholt, B; Heuft, G; Luger, TA; Schneider, G; Schürmeyer-Horst, F; Ständer, S; Weishaupt, C, 2009) |
"Pruritus is a common and bothersome problem in 30-50% of hemodialysis patients." | ( Eskandari, D; Ganji, MR; Khashayar, P; Meysamie, AP; Razeghi, E; Togha, M, 2009) |
"Pruritus is a common complication of end-stage renal disease (ESRD), affecting about one-third of dialysis patients." | ( Manenti, L; Tansinda, P; Vaglio, A, 2009) |
"As pruritus is an unpleasant sensation and the associated scratching aggravates the skin eruption considerably, it is important to control this symptom when treating AD." | ( Fukiwake, N; Furue, M; Hachisuka, J; Kido, M; Takeuchi, S, 2009) |
"Pruritus is one of the frequent discomforting complications in patients with end-stage renal disease." | ( Farrokhi, F; Firouzan, A; Nasli Esfahani, E; Nasrollahi, A; Pour-Reza-Gholi, F, 2007) |
"Bathing pruritus is a common finding among young adult Nigerians in the general population." | ( Eze, KC; Irekpita, E; Momoh, MO; Oziegbe, E; Salami, TA; Samuel, SO, 2009) |
"Pruritus is one of the key symptoms in atopic dermatitis (AD)." | ( Greisenegger, EK; Kopp, T; Stingl, G; Zimprich, A; Zimprich, F, 2009) |
"The uremic pruritus is a very painful symptom suffered by chronic haemodialysis patients and is observed in 22 to 74% of the subjects." | ( Durrant-Finn, U; Mügge, C; Nenoff, P; Osten, B, 2009) |
"Pruritus is an unpleasant sensation leading to scratching." | ( Reich, A; Szepietowski, JC, 2010) |
"Pruritus is commonly associated with cholestatic disorders and shows wide interindividual variability." | ( Fábrega, E; Pons-Romero, F; Terán, A, 2010) |
"Although pruritus is common, some cats may harbour the mites without clinical signs." | ( Juuti, KH; Palojärvi, JH; Rajaniemi, RL; Saari, SA; Saijonmaa-Koulumies, LE; Väisänen, KM, 2009) |
"Fatigue and pruritus are the main symptoms but patients may also be asymptomatic." | ( den Ouden-Muller, JW; Kuiper, EM; van Buuren, HR, 2009) |
"Generalized pruritus is a significant complication in end-stage renal disease patients." | ( Jafari, P; Sagheb, MM; Samani, SM; Shilian, S; Vessal, G, 2010) |
"Pruritus is one of the common problems in patients on hemodialysis." | ( Ala, S; Bari, A; Haj-Heydari, Z; Kashi, Z; Makhlough, A, 2010) |
"Pruritus is the predominant symptom of skin disease." | ( Patel, T; Yosipovitch, G, 2010) |
"The therapy of pruritus is challenging and at present takes on an individualistic approach." | ( Patel, T; Yosipovitch, G, 2010) |
"When pruritus is untreated, the incessant scratching response by the patient can increase the inflammatory response, resulting in aggravation of disease symptoms and severity, increasing flares and worsening patient quality of life." | ( Boguniewicz, M; Fleischer, AB, 2010) |
"Chronic pruritus is a global clinical problem with a high impact on the quality of life and lack of specific therapies." | ( Herrgott, I; Luger, TA; Siepmann, D; Ständer, S; Sunderkötter, C, 2010) |
"Pruritus is a common and disabling symptom in cholestatic disorders." | ( Beuers, U; Geenes, VL; Kondrackiene, J; Kremer, AE; Kuiper, EM; Kulik, W; Martens, JJ; Moolenaar, WH; Oude Elferink, RP; Prieto, J; Ruëff, F; Rust, C; van Buuren, HR; van Erpecum, KJ; Williamson, C, 2010) |
"Pruritus is a common adverse effect of opioid treatment." | ( Sugimoto, Y; Yamamoto, A, 2010) |
"Uraemic pruritus is a common and distressing symptom in patients undergoing haemodialysis." | ( Alivanis, P; Aperis, G; Arvanitis, A; Paliouras, C; Zervos, A, 2010) |
"Pruritus is an integral part of the patient's symptoms in numerous dermatological and systemic diseases in humans and animals." | ( Grundmann, S; Metz, M; Ständer, S, 2011) |
"Pruritus is the most common side effect of naproxen." | ( Akyazi, H; Baltaci, D; Kara, IH; Mungan, S, 2011) |
"Pruritus is a frequent symptom in patients with cholestatic liver diseases." | ( Beuers, U; Kremer, AE; Oude Elferink, RP, 2011) |
"Itching (pruritus) is perhaps the most common symptom associated with inflammatory skin diseases and can be a lead symptom ofextracutaneous disease (e." | ( Buddenkotte, J; Maurer, M; Steinhoff, M, 2010) |
"Itch, or pruritus, is an important clinical problem whose molecular basis has yet to be understood." | ( Dong, X; Liu, Q; Meeker, S; Patel, KN; Undem, BJ, 2011) |
"Pruritus is a frequent symptom in patients with cholestatic liver diseases." | ( Beuers, UH; Kremer, AE; Martens, JJ; Oude Elferink, RP, 2011) |
"Dry skin and pruritus are common complication of end-stage renal diseases (ESRD), affecting up to 80% of dialysis patients." | ( Castello, M; Milani, M, 2011) |
"In many diseases, pruritus is not effectively treated with antihistamines, indicating the involvement of nonhistaminergic mechanisms." | ( Borzan, J; Hartke, TV; Johanek, LM; LaMotte, RH; Meyer, RA; Ringkamp, M; Schepers, RJ; Shim, B; Shimada, SG, 2011) |
"Scalp pruritus is a common complaint that is considered a diagnostically and therapeutically challenging situation." | ( Bin Saif, GA; Ericson, ME; Yosipovitch, G, 2011) |
"Pruritus is the most common chronic skin complication of SM, which adversely affects the quality of life (QoL)." | ( Amiri, M; Beiraghdar, F; Davoudi, SM; Hoseininejad, SL; Kolivand, M; Panahi, Y; Sahebkar, A, 2012) |
"Pruritus is a severe symptom in patients with cholestatic hepatobiliary disease; it can greatly reduce the quality of life." | ( Beuers, U; Kremer, AE; Maillette de Buy Wenniger, L; Oude Elferink, RP, 2011) |
"Post burn pruritus is a well recognised symptom in almost all burn patients." | ( Gupta, AK; Lamba, S; Paul, MK; Prabha, R; Rao, AL; Zachariah, JR, 2012) |
"Pruritus is a severe symptom that is difficult to treat in atopic dermatitis patients." | ( Iwao, H; Izumi, Y; Miura, K; Nakao, T; Osada-Oka, M; Samukawa, K; Shiota, M, 2012) |
"Pruritus is a common complaint in patients undergoing maintenance hemodialysis." | ( Davarpanah Jazi, AH; Emami, A; Faghihi, G; Moeenzadeh, F; Monghad, M; Najafabadi, MM; Sharif, N, 2012) |
"Pruritus is a seriously disabling symptom accompanying many cholestatic liver disorders." | ( Beuers, U; Davies, NA; Engert, A; Jalan, R; Kremer, AE; Kuiper, EM; Leckie, P; Mettang, T; Oude Elferink, RP; Raap, U; Reiners, KS; Rust, C; Schaap, FG; van Buuren, HR; van Dijk, R; van Erpecum, KJ, 2012) |
"Chronic pruritus is frequently refractory to currently available treatments." | ( Antal, A; Bernhard, JD; Lotts, T; Phan, NQ; Ständer, S, 2012) |
"Pruritus is a troublesome complication in patients with cholestatic liver disease." | ( Bunchorntavakul, C; Reddy, KR, 2012) |
"Itch, also known as pruritus, is a common, intractable symptom of several skin diseases, such as atopic dermatitis and xerosis." | ( Berta, T; Dong, X; Gao, YJ; Ji, RR; Liu, Q; Liu, T; Liu, Y; Liu, YC; Lü, N; Ma, Q; Park, CK; Xu, ZZ; Zhang, L, 2012) |
"Pruritus is a disabling complication of cholestatic liver disorders." | ( Cassiman, D; Decock, S; Fevery, J; Laleman, W; Nevens, F; Pelt, JV; Roelandts, R; Steenbergen, WV; Verslype, C, 2012) |
"Pruritus is a common symptom of hepatobiliary disorders and may considerably diminish quality of life." | ( Beuers, U; Kremer, AE; Oude Elferink, RP, 2012) |
"Brachioradial pruritus is a characteristic clinical condition with a deep intense itching, tingling or burning sensation localized to the dorsolateral part of the upper extremities." | ( Bygum, A; Uldall Pallesen, KA, 2012) |
"Uremic pruritus is common among dialysis patients." | ( Barrón, B; Lauxmann, JE; Marquez, D; Martinatto, C; Novoa, PA; Orías, M; Peixoto, AJ; Ramonda, C; Romero, CA; Vukelic, VL, 2012) |
"Pruritus is common in dialysis patients." | ( Atalay, H; Biyik, Z; Covic, A; Gaipov, A; Goldsmith, D; Guney, F; Kanbay, M; Solak, Y; Turk, S, 2012) |
"Opioid-induced pruritus is not usually considered a frequently occurring complication, but may be easily misinterpreted as being dysphoria in recovery." | ( Bauquier, SH, 2012) |
"Pruritus is the most common presenting symptom." | ( Gunning, K; Kiraly, B; Pippitt, K; Sayler, M, 2012) |
"Pruritus is a common adverse effect of opioids, particularly after spinal and epidural administration." | ( Frost, J; Spigset, O, 2012) |
"Pruritus is one of the most common cutaneous complications in hemodialysis patients." | ( Bicmohamadi, AR; Emadi, N; Khademloo, M; Makhlough, A; Sedighi, O, 2013) |
"PONV and pruritus are frequent side-effects of neuraxial morphine." | ( Dominguez, JE; Habib, AS, 2013) |
"Uremic pruritus is a common and distressing symptom occurring in 42% to 75% of end-stage renal dialysis (ESRD) patients, even in patients who are adequately dialyzed." | ( Chan, KY; Chan, ML; Cheng, HW; Li, CW; Sham, MK; Wong, H; Yip, T, 2013) |
"Pruritus is a frequent adverse event after administration of morphine." | ( Du, BX; Shi, XY; Song, ZM; Wang, K; Xu, FY; Zhang, H; Zou, Z, 2013) |
"Pruritus is a common adverse event in patients being treated with chloroquine for P." | ( Alecrim, MG; Alexandre, MA; Ballut, PC; Lacerda, MV; Orlando, AC; Siqueira, AM, 2013) |
"Pruritus is a common and bothersome problem among uremic patients which negatively affects life quality and prognosis of the patient." | ( Abbasi, M; Gatmiri, SM; Lessan-Pezeshki, M; Mahdavi-Mazdeh, M, 2013) |
"Uremic pruritus is a common complication in patients undergoing dialysis." | ( Dwornicki, M; Gawlik, R; Grabiec, P; Grzeszczak, W; Kuźniewicz, R; Owczarek, A; Snit, M; Walaszczyk, M; Łącka-Gaździk, B, 2013) |
"Severe persistent pruritus is a common, but incompletely characterized, complication of hydroxyethyl starch (HES) infusion." | ( Metze, D; Osada, N; Richter, L; Ständer, S, 2014) |
"Pruritus is a common problem among hemodialyzed patients." | ( Fishbane, S; Hazzan, A; Kline, M; Moledina, D; Patel, C; Sakhiya, V; Schanler, M; Shirazian, S, 2013) |
"Chronic itch, or pruritus, is associated with a wide range of skin abnormalities." | ( Barry, DM; Battey, JF; Chen, ZF; Cornelius, LA; Demehri, S; Hampton, L; Huo, FQ; Jeffry, J; Kim, S; Kopan, R; Li, H; Liu, XY; Liu, ZC; Ma, K; Turkoz, A; Wan, L; Zhao, ZQ; Zhong, J, 2013) |
"Pruritus is a common symptom of skin diseases, and is associated with impaired sleep quality and a considerable reduction in the patient's quality of life." | ( Suwa, E; Tomono, A; Ueno, K; Yamaura, K, 2014) |
"Post-burn pruritus is a common distressing consequence of burn wounds." | ( Cho, SI; Choi, MG; Choi, YH; Kim, HO; Kwak, IS; Park, CW; Yang, YS, 2015) |
"Pruritus is an unpleasant sensation of the skin, which triggers a desire to scratch or rub." | ( Lotts, T; Ständer, S, 2014) |
"Neurogenic pain and pruritus are the common chief complaints at dermatology office visits." | ( Boyd, K; Patterson, JW; Shea, SM, 2014) |
"Pruritus is usually managed using resins; further steps are needed in resistant cases with the use of rifampicin, naltrexone, sertraline, or invasive procedures such as albumin dialysis." | ( Parés, A, 2014) |
"Pruritus is common among patients with end-stage renal disease undergoing dialysis, and the pathogenesis can be explained by several mechanisms." | ( Jiao, S; Meng, J; Ren, W; Xiao, Y; Yue, J; Zhao, T, 2015) |
"Paraneoplastic pruritus is defined as pruritus that occurs before or during the natural evolution of a hematologic disease." | ( Casanova, M; Domínguez, AR; Goitia, BT; Siles, MG; Villafranca, JJ, 2014) |
"Pruritus is the main symptom of dermatitides, such as atopic dermatitis, and is very difficult to control." | ( Andoh, T; Kuraishi, Y, 2014) |
"Pruritus is a debilitating symptom that can be associated with cutaneous involvement by an underlying malignancy." | ( Carlberg, VM; Girouard, SD; Lee, JJ; Mostaghimi, A, 2016) |
"Pruritus is an important symptom in psoriasis with no targeted treatment." | ( Anand, P; Anand, U; Boyce, B; Mainero, V; Robinson, J; Roblin, D; Sandy, J; Wickramasinghe, R; Yosipovitch, G, 2015) |
"Pruritus is a manifestation of chronic liver disease." | ( Agrawal, S; Aoun, E; Babich, M; O'Connor, R, 2015) |
"Pruritus is one of the cardinal symptoms found in patients with leukemic cutaneous T cell lymphoma (CTCL)." | ( Benoit, BM; Cedeno-Laurent, F; Kim, EJ; Rook, AH; Singer, EM; Vittorio, CC; Wysocka, M; Yosipovitch, G, 2015) |
"Uremic pruritus is a common and deleterious condition among hemodialysis (HD) patients." | ( Alcorn, H; Berg, J; Hait, H; Hawi, A; Hines, C; Sciascia, T, 2015) |
"Uremic pruritus is a common complication in patients with chronic kidney disease." | ( Morshedi, J; Nakhaee, S; Nasiri, A; Waghei, Y, 2015) |
"Diarrhoea, rash and pruritus are rather common side effects of clopidogrel." | ( Nazzaro, G; Vaira, F; Veraldi, S, 2015) |
"Pruritus is a common side effect of intrathecal fentanyl or sufentanil that decreases patient satisfaction and may delay hospital discharge." | ( Guglielminotti, J; Li, G; Moitra, V; Prin, M, 2016) |
"Dose-dependent pruritus is a common adverse effect, but may be overcome through dose-titration." | ( Gershwin, ME; Hirschfield, GM; Trivedi, PJ, 2016) |
"Pruritus is a common and often times difficult to treat symptom in many dermatologic and systemic diseases." | ( Kwatra, SG; Sharma, D, 2016) |
"Opioid-induced pruritus is a common side effect of opioid treatment in patients with acute pain associated with surgery or childbirth." | ( Jannuzzi, RG, 2016) |
"Pruritus is a characteristic clinical sign of allergic skin conditions including atopic dermatitis (AD) in the dog." | ( Aleo, MM; Fleck, TJ; Galvan, BA; Gonzales, AJ; Greenwood, KG; Humphrey, WR; Mahabir, SP; McCall, RB; Tena, JK, 2016) |
"Scar pruritus is frequently encountered in clinical practice (particularly in burn patients) owing to its poorly known pathogenesis and difficult treatment." | ( Alonso, PE; Rioja, LF, 2016) |
"Chronic itch (pruritus) is an important clinical problem." | ( Chen, M; Gegen, T; Guo, CJ; He, Q; Hu, D; Li, F; Liu, Q; Shi, H; Tang, M; Tang, Z; Wang, C; Wang, Z; Yang, N; Yang, Y; Yu, G; Zhu, C, 2016) |
"Pruritus is a common and distressing symptom that affects patients with chronic kidney disease (CKD)." | ( Chen, SC; Chung, FM; Houng, JY; Hsu, CC; Hung, WC; Lee, YJ; Lu, YC; Tang, WH; Tsai, IT; Wang, CP; Yu, TH, 2016) |
"Chronic pruritus is a distressing symptom that is often refractory to treatment." | ( Kwatra, SG; Matsuda, KM; Schonfeld, AR; Sharma, D, 2016) |
"Pruritus is one of the frustrating skin manifestations of advanced renal failure." | ( Etminan, A; Foroutan, N; Nikvarz, N; Shojai Shahrokh Abadi, M, 2017) |
"Pruritus is a severe symptom accompanying chronic cholestasis." | ( Cohen, J; Debray, D; Gonzales, E; Gottrand, F; Habes, D; Jacquemin, E; Rivet, C; Thébaut, A, 2017) |
"Chronic pruritus is a common problem in patients with inflammatory skin diseases as well as in subjects with dry or sensitive skin." | ( Metz, M; Staubach, P, 2016) |
"Pruritus is a symptom arising from a plethora of dermatological, neurological, and systemic conditions." | ( Pereira, MP; Ständer, S, 2016) |
"Pruritus is common in pregnancy." | ( Lambert, J, 2016) |
"Itch (pruritus) is one of the most disabling syndromes in patients suffering from skin, liver, or kidney diseases." | ( Chen, LH; Cheng, RX; Gao, YJ; Huang, Y; Liu, T; Liu, TT; Wang, S; Wang, XL; Zhou, FM; Zhou, Y, 2017) |
"Pruritus is the major symptom of ocular allergy but currently available treatments are often ineffective." | ( Chen, N; Huang, Y; Li, C; Liu, F; Ma, C; Xie, Y; Xu, L; Yang, Q; Zhou, M, 2017) |
"Chronic pruritus is difficult to treat." | ( Agelopoulos, K; Loser, K; Lotts, T; Luger, TA; Phan, NQ; Schmaus, G; Ständer, S, 2017) |
"Uremic pruritus is one of the most common disabling symptoms in patients with end-stage renal disease." | ( Ezzat Zadegan, S; Mahmudpour, M; Pakfetrat, M; Raiss Jalali, GA; Roozbeh, J; Sagheb, MM, 2017) |
"Pruritus is frequently associated with the development of chronic liver diseases such as cholestasis and chronic viral infection, and the accumulation of bile acids in patients' sera and tissues as a consequence of liver damage is considered the main cause of pruritus." | ( Alhmada, Y; Haikel, Y; Hannig, M; Hassan, M; Hassan, SL; Megahed, M; Murad, F; Selimovic, D, 2017) |
"Uremic pruritus is an undesirable complication of end stage renal disease (ESRD)." | ( Hashemi, N; Malekmakan, L; Pakfetrat, M; Tadayon, T, 2018) |
"Pruritus is difficult to prevent; however, pentazocine has been shown to be an effective treatment." | ( Doi, K; Hirabayashi, M; Imamachi, N; Kishimoto, T; Saito, Y, 2017) |
"Pruritus is one of the most common adverse effects associated with neuraxial morphine." | ( Sun, L; Wang, W; Zhou, L, 2017) |
"Itch, or pruritus, is a hallmark feature of atopic dermatitis (AD)." | ( Elmariah, SB, 2017) |
"Pruritus is a disabling symptom accompanying chronic cholestasis." | ( Debray, D; Gonzales, E; Thébaut, A, 2017) |
"Pruritus is a major symptom of several dermatological diseases but has limited therapeutic options available." | ( Carcasona, C; Eichhorn, P; Gavaldà, A; Godessart, N; Pérez, B; Tarrasón, G, 2017) |
"Uremic pruritus is an unpleasant symptom in patients undergoing hemodialysis, and the underlying mechanisms remain unclear." | ( Andoh, T; Li, S; Maki, T; Uta, D, 2017) |
"Uremic pruritus is a common and burdensome symptom afflicting patients with advanced chronic kidney disease (CKD) and has been declared a priority for CKD research by patients." | ( Askin, N; Bohm, C; Komenda, P; Lerner, B; Rigatto, C; Shaw, J; Simonsen, E; Tangri, N, 2017) |
"Pruritus is often indistinguishable from neuropathic pain." | ( Amin, A; Kaul, I; Meyer, WJ; Rosenberg, L; Rosenberg, M, 2018) |
"Pruritus is a distressing symptom seen in palliative care." | ( Kraut, RY, 2017) |
"Pruritus is an unpleasant irritation symptom that can be related to various systemic and dermatological conditions." | ( Al-Shathir, M; Baumrucker, SJ; Moulton, M; Rashid, S; Trivedi, DD, 2018) |
"Chronic pruritus is a difficult condition to treat and is associated with several comorbidities, including insomnia, depression, and decreased quality of life." | ( Alhariri, JM; He, A; Kwatra, MM; Kwatra, SG; Sweren, RJ, 2017) |
"Post-burn pruritus is a common and distressing sequela of burn scars." | ( Choi, YW; Chung, BY; Kim, HJ; Kim, HO; Park, CW; Song, DK; Woo, SY, 2017) |
"Pruritus is a distressing hallmark of the uremic condition, affecting approximately 60% of hemodialysis patients." | ( Crawford, PW; Hait, H; Kumar, J; Mathur, VS; Sciascia, T, 2017) |
"Aquagenic pruritus is one of the main clinical features of polycythemia vera." | ( Lelonek, E; Matusiak, Ł; Szepietowski, JC; Wróbel, T, 2018) |
"Pruritus is the most common side effect of intrathecal morphine, especially in parturients." | ( Abdelsalam, K; Aly, M; Farrag, W; Ibrahim, A; Mohamed, H; Tawfik, A, 2018) |
"Chronic itch or pruritus is a debilitating disorder that is refractory to conventional anti-histamine treatment." | ( Bardoni, R; Barry, DM; Bruchas, MR; Chen, ZF; Huo, FQ; Jeffry, J; Jin, H; Kim, S; Li, H; Li, YQ; Liu, XY; Meng, QT; Mo, P; Munanairi, A; Peng, JH; Wan, L; Wu, ZY; Yang, Q; Yin, J; Yin, JB; Zhou, XY, 2018) |
"Neuropathic pruritus is a challenging condition that can be caused by injury or dysfunction in any part of the nervous system." | ( Fostini, AC; Rosen, JD; Yosipovitch, G, 2018) |
"Pruritus is a common symptom in cutaneous T-cell lymphoma (CTCL) and critically affects the quality of life of patients." | ( Guitart, J; Martinez-Escala, ME; Serrano, L; Zhou, XA, 2018) |
"Pruritus is the most common complication of intrathecal morphine; however, its exact molecular mechanism is unclear, and treatment is challenging." | ( Huang, Y; Li, S; Qin, J; Shen, L; Wang, W, 2018) |
"Uremic pruritus is a common symptom in chronic renal failure patients with undefined pathophysiology." | ( Abbade, LP; Gobo-Oliveira, M; Miot, HA; Ogata, MS; Pigari, VG; Ponce, D, 2018) |
"Pruritus is associated with various skin diseases, dry skin, and with it an impaired skin barrier function." | ( Barysch, M; Borelli, S; Gasser, UE; Hasan-Ali, O; Kunz, M; Nägeli, M; Nobbe, S; Simon, D; Wildi, E, 2018) |
"Pruritus is a common symptom with primary biliary cholangitis." | ( Carrion, AF; Levy, C; Rosen, JD, 2018) |
"Pruritus is a common symptom in patients with primary biliary cholangitis (PBC) for which ileal bile acid transporter (IBAT) inhibition is emerging as a potential therapy." | ( Corrigan, M; Hegade, VS; Hirschfield, GM; Holmes, E; Jones, DE; Kendrick, S; Marchesi, JR; McDonald, JAK; Pechlivanis, A; Rees, D; Taylor-Robinson, SD, 2019) |
"Scalp pruritus is a frequent problem encountered in dermatological practice." | ( Rattanakaemakorn, P; Suchonwanit, P, 2019) |
"Pruritus is one of the common side effects of intrathecal or epidural injection of opioids." | ( Kang, MR; Pan, AZ; Ye, YS; Yi, WM; Zhang, B; Zhen, Y, 2019) |
"Pruritus is one of the most common and disabling symptoms of liver disease such as Primary Sclerosing Cholangitis and Primary Biliary Cholangitis." | ( Ataei, S; Hasanzarrini, M; Kord, L; Larki, A; Mehrpooya, M; Seyedtabib, M; Yasrebifar, F, 2019) |
"Itch or pruritus is an unpleasant sensation that brings about a negative impact on quality of life, and serious itch may lead to dose reduction and even discontinuation." | ( Li, TT; Yang, R; Yao, RS; Yao, S; Yu, MJ, 2019) |
"Nocturnal pruritus is a hallmark symptom of bullous scabies." | ( Holland, V; Salame, N, 2019) |
"Chronic pruritus is a distressing symptom associated with various dermatological conditions and systemic diseases." | ( Ständer, S; Yosipovitch, G, 2019) |
"Pruritus is a leading cause of reduced health-related quality of life (QoL) in atopic dermatitis (AD)." | ( Bushmakin, AG; Cappelleri, JC; Gerber, RA; Luger, T; Ports, WC; Ständer, S; Tallman, AM; Tan, H; Tom, WL; Yosipovitch, G; Zielinski, MA, 2019) |
"CKD-associated pruritus is one of the common symptoms in patients undergoing dialysis, thus contributing to the diminished and compromised quality of life." | ( Chan, KG; Khan, TM; Kun, LS; Lai, PS; Lee, LH; Rehman, IU, 2020) |
"Aquagenic pruritus is classically associated to PV." | ( Carré, JL; Chauveau, A; Couturier, MA; Ianotto, JC; Le Calloch, R; Le Gall-Ianotto, C; Lippert, E; Misery, L, 2019) |
"Pruritus is an unexpected symptom observed in cholestasis and its mechanism is still unclear." | ( Maeng, HJ; Sanjel, B; Shim, WS, 2019) |
"Pruritus is a major symptom of many inflammatory diseases and impacts greatly the quality of life in patients." | ( André, F; Church, MK; Fluhr, JW; Hawro, T; Maurer, M; Metz, M, 2020) |
"Opioid-induced pruritus is prevalent after neuraxial administration of opioid." | ( Buszta, K; Harenberg, JL; Hestand, JD; Tubog, TD, 2019) |
"Pruritus is an important, prevalent but often neglected symptom in patients with advanced chronic kidney disease (CKD) or on dialysis." | ( Cupisti, A; Gallieni, M; Piccoli, GB, 2020) |
"Uremic pruritus is one of the most prevalent and bothersome dermatologic symptoms in patients with end-stage renal disease." | ( Castillo, RL; Dofitas, BL; Eusebio-Alpapara, KMV, 2020) |
"Pruritus is most commonly associated with a primary skin disorder such as atopic dermatitis (AD), psoriasis, etc." | ( Yamaura, K, 2019) |
"Uraemic pruritus is a common symptom in patients with chronic kidney disease undergoing haemodialysis (HD) treatment." | ( Kozioł-Gałczyńska, M; Krajewski, P; Szepietowski, JC; Wieczorek, A, 2020) |
"Pruritus is one of the most common problems in patients with chronic renal failure." | ( Ghorghani, M; Hoseininia, S; Mohammadi Kebar, S; Sharghi, A, 2020) |
"Post-burn pruritus is the pruritus that occurs after burn during the rehabilitation and healing process of burn wounds." | ( Chung, BY; Jung, MJ; Kang, SY; Kim, HB; Kim, HO; Kwak, IS; Park, CW, 2020) |
"Uremic pruritus is a common boring complaint in patients suffering from chronic renal failure." | ( Jahromi, SE; Karjalian, F; Momennasab, M; Yoosefinejad, AK, 2020) |
"Chronic pruritus is a cardinal symptom of the inflammatory skin disease atopic dermatitis (AD)." | ( Abels, C; Kilic, A; Soeberdt, M, 2020) |
"Pruritus is a debilitating symptom of cholestatic diseases such as primary biliary cholangitis and primary sclerosing cholangitis and often results in major reduction in quality of life for afflicted patients." | ( Golpanian, RS; Levy, C; Yosipovitch, G, 2021) |
"Senile pruritus is common, yet its etiology remains unknown." | ( Cai, M; Gao, N; Han, G; Lu, L; Ma, X; Zhao, Z, 2020) |
"Mechanisms of pruritus are implicated in the dysregulation of the metabolites in the spinal cord." | ( Chen, YL; Fan, L; He, ZG; Wang, Q; Xiang, HB; Xiong, J, 2020) |
"Pruritus is one of the leading symptoms of dermatitis herpetiformis (DH), however, studies on the pathogenesis of pruritus are scarce." | ( Chen, X; Liu, H; Liu, T; Liu, Y; Lu, X; Sun, L; Sun, Y; Wang, J; Xia, Q; Zhang, F, 2020) |
"Aquagenic pruritus is a rare debilitating condition, which can be idiopathic, iatrogenic, or associated with systemic disease." | ( Admani, S; Friedlander, MSH, 2021) |
"Pruritus is one of the most common side effects of epidural morphine administered for post-surgery analgesia, and pregnant women tend to be highly susceptible." | ( Cao, H; Gao, Y; Niu, K; Shangguan, W; Tian, X; Xu, F; Zhan, G; Zhang, Y, 2021) |
"Chronic pruritus is a symptom that commonly observed in neurological diseases." | ( Fang, Y; Ma, C; Tao, J; Wang, T, 2021) |
"Pruritus is the most frequent adverse event during treatment with OCA." | ( Cazzagon, N; Floreani, A, 2021) |
"Pruritus is known to be a common complication in hepatitis patients, but the exact frequency and degree are not fully elucidated." | ( Asabe, S; Asano, T; Fujiwara, J; Ishii, T; Kashima, H; Koito, Y; Mashima, H; Matsumoto, K; Matsumoto, S; Miura, T; Miyatani, H; Morino, M; Otake, H; Sekine, M; Takahashi, Y; Tsuboi, R; Uehara, T; Yoshikawa, S; Yuhashi, K, 2021) |
"Pruritus is a common debilitating symptom experienced by hemodialysis patients." | ( Bolanos, CG; Mair, RD; Meyer, TW; Pham, NM; Sirich, TL, 2021) |
"Pruritus is an annoying symptom with an unclear pathogenesis accompanied by chronic cholestasis." | ( Elakel, W; Elshiwy, Y; Koofy, NE; Okasha, S; William, H; Yassin, N, 2021) |
"Neuropathic pruritus is a type of chronic pruritus related to damaged small fibers." | ( Lou, K; Murphy, S; Talbot, C, 2022) |
"The symptom of pruritus is frequently overlooked by dermatologists, and treatments are often primarily focused on the gross appearance of the scar." | ( Hawash, AA; Ingrasci, G; Nouri, K; Yosipovitch, G, 2021) |
"Pruritus is one of the major symptoms of sensitive skin." | ( Gong, Q; Hua, W; Jiang, P; Li, L; Wan, R; Zuo, Y, 2021) |
"Uremic pruritus is a distressful complication of chronic kidney disease and results in impaired quality of life and higher mortality rates." | ( Chuo, HE; Kuo, KL; Liao, JF; Lu, PH, 2021) |
"Pruritus is the sensation of itching; it can be caused by dermatologic and systemic conditions." | ( Honeycutt, JD; Rupert, J, 2022) |
"Pruritus is a common symptom in patients with systemic sclerosis and has a tremendous effect on the quality of life." | ( Berookhim, J; Levy, Y; Meridor, K, 2022) |
"Chronic pruritus is one of the most common conditions in dermatology and a common manifestation in many systemic diseases." | ( Handjani, F; Jaladat, AM; Javaheri, R; Moini Jazani, A; Parvizi, MM; Salami, MH, 2022) |
"Pruritus is the main contributor of decreased quality of life in patients with AD." | ( Feldman, SR; Mohney, LA; Singh, R, 2023) |
"Scalp pruritus is a common skin problem that remains therapeutic challenge." | ( Chang, X; Li, X; Shi, Y; Yan, H; Yang, F; Zhang, M; Zhang, Y, 2022) |
"Localized senile pruritus is a continued health problem for the elderly." | ( Fei, JB; He, HQ; Pei, Q; Qin, HH; Shen, WT; Wang, GJ; Yu, Y, 2022) |
"Pruritus is a symptom that adversely affects the quality of life of patients with epidermolysis bullosa (EB)." | ( Ahramiyanpour, N; Hosseini, SA; Parvizi, MM; Saki, N; Shafie'ei, M; Vahedi, S, 2022) |
"Pruritus is one of the most common and challenging side effects of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) and has impaired patients' quality of life and treatment compliance." | ( Feng, W; Huang, L; Huang, Y; Liu, J; Ma, W; Ma, Y; Wu, X; Yang, Y; Zhang, L; Zhang, Y; Zhao, H; Zhou, H; Zhou, T, 2022) |
"Chronic pruritus is a classic symptom in patients with primary biliary cholangitis." | ( Düll, MM; Kremer, AE, 2022) |
"Pruritus is a common symptom of PBC, and evidence regarding the most effective antipruritic agents available is lacking." | ( Barba Bernal, R; Bonder, A; Ferrigno, B; Gerger, H; Goyes, D; Medina-Morales, E; Patwardhan, V; Trivedi, HD, 2023) |
"Pruritus is a frequent symptom experienced by patients with myeloproliferative neoplasms (MPN)." | ( Ficheux, AS; Herbreteau, L; Ianotto, JC; Le Gall-Ianotto, C; Lippert, E; Misery, L; Pan-Petesch, B; Rio, L, 2023) |
"Pruritus is the most common skin symptom in patients with CKD, especially in end-stage renal disease." | ( Dong, X; Jing, T; Jun, S; Shen, X; Sheng, M; Sun, J; Sun, Y; Tang, Z; Wang, C; Yang, Y; Yu, G; Zhu, C, 2023) |
"Chronic pruritus is burdensome for patients with chronic kidney disease (CKD)." | ( Awad, A; Menzaghi, F; Munera, C; Spencer, RH; Yosipovitch, G, 2023) |
"Pruritus is identified as an adverse drug reaction to arsenic trioxide, but the association of arsenic exposure with pruritus has not been investigated." | ( Chen, M; Chen, X; Duan, Y; He, M; Huang, X; Huang, Y; Huang, Z; Jing, D; Shen, M; Su, J; Xiao, Y; Yang, G; Yang, S, 2023) |
"Itch (pruritus) is a common unpleasant feeling, often accompanied by the urge of scratching the skin." | ( Chu, YX; Du, LX; Maoying, QL; Mi, WL; Qiao, Z; Wang, YQ; Yang, YC; Yang, YY; Yi, T; Zhu, JY, 2023) |
"Chronic pruritus is frequently seen in daily dermatological practice and is associated with marked impact on quality of life." | ( Kamsteeg, M; Kouwenhoven, TA; van de Kerkhof, PCM, 2023) |
"Keloid-associated pruritus is a common manifestation and has negative impacts on quality of life." | ( Biazus Soares, G; Mahmoud, O; Yosipovitch, G, 2023) |