Bronchiolitis, Viral

An acute inflammatory disease of the lower RESPIRATORY TRACT, caused by paramyxoviruses, occurring primarily in infants and young children; the viruses most commonly implicated are PARAINFLUENZA VIRUS TYPE 3; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; and METAPNEUMOVIRUS.

Synonym
Bronchiolitis, Viral

Excerpt	Reference
"Viral bronchiolitis is a common disease that may result in persistent airway abnormalities."	( Castleman, WL; Clough, JJ; Lemanske, RF; McAllister, PK; Sheth, KK; Sorkness, RL, 1994)
"Viral bronchiolitis is the commonest cause of hospital admission in young infants."	( Fitzgerald, DA; Kilham, HA, 2004)
"Acute viral bronchiolitis is associated with airway obstruction and turbulent gas flow."	( Cambonie, G; Ducruet, T; Gupta, V; Liet, JM, 2010)
"Viral bronchiolitis is the leading cause of hospitalization in young infants."	( Beigelman, A; Brody, SL; Cannon, CL; Gunsten, SP; Mikols, CL; Walter, MJ, 2010)
"Viral bronchiolitis is an acute infection and inflammatory disease of the respiratory tract, with infants typically presenting with the most severe symptoms."	( Abboud, PA; Roth, PJ; Rowin, ME; Skiles, CL; Stolfi, A, 2012)
"Acute viral bronchiolitis is associated with airway obstruction and turbulent gas flow."	( Cambonie, G; Ducruet, T; Gupta, V; Liet, JM, 2015)
"Acute viral bronchiolitis is a frequent disease in infancy."	( Brevis Nuńez, F; Dohna-Schwake, C; Durand, P; Felderhoff-Müser, U; Heister, P; Hofmann, M; Jacobs, A; Mücher, K; Roll, C; Rothoeft, T; Seiffert, P; Stehling, F; Stein, A; Tissières, P; Zuzak, T, 2018)
"Viral bronchiolitis is the most common cause of admission to hospital for infants in high-income countries."	( Babl, FE; Borland, ML; Dalziel, SR; Haskell, L; O'Brien, S; Oakley, E; Plint, AC, 2022)

Excerpt	Reference
"Viral bronchiolitis affects 20%-30% of infants; because there is no known effective treatment, it is important to identify risk factors that contribute to its pathogenesis."	( Carroll, KN; Cooper, WO; Dorris, SL; Dupont, W; Gebretsadik, T; Hartert, TV; Hartman, TJ; Mitchel, EF; Tylavsky, FA; Veeranki, SP, 2014)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	95 (26.17)	23.3326
1990's	61 (16.80)	12.5806
2000's	109 (30.03)	18.1394
2010's	81 (22.31)	28.8240
2020's	17 (4.68)	9.53

Drug	Relationship Strength	Studies	Trials
ammonium hydroxide	low	1	0
carbon monoxide	low	1	0
lactic acid	low	1	0
dimethyl sulfoxide	medium	1	1
formaldehyde	low	1	0
hydrogen carbonate	low	1	0
histamine	low	10	0
racepinephrine	medium	3	2
sulfur dioxide	low	1	0
albuterol	medium	44	19
theophylline	low	6	0
bromhexine	low	1	0
chloral hydrate	low	2	0
chlorpheniramine	low	1	0
furosemide	medium	3	1
guaifenesin	low	7	0
isoetharine	low	2	0
isoproterenol	low	3	0
metaproterenol	low	3	0
apnea	low	16	0
procaine	low	1	0
propranolol	low	1	0
terbutaline	medium	2	1
prednisolone	medium	5	3
hydroxyproline	low	1	0
spironolactone	low	1	0
penicillamine	low	1	0
prednisone	medium	2	1
penicillin g	low	2	0
chloramphenicol	low	2	0
kanamycin a	low	1	0
phenylephrine	medium	1	1
cloxacillin	low	2	0
methacholine chloride	low	5	0
colchicine	low	1	0
ampicillin	medium	7	3
mannitol	low	1	0
phosgene	low	2	0
phencyclidine	low	1	0
methylprednisolone	low	3	0
diphenhydramine hydrochloride	medium	2	1
nitroblue tetrazolium	low	1	0
ephedrine	low	1	0
aminophylline	low	5	0
betamethasone	medium	2	1
acetylcysteine	medium	1	1
erythromycin	low	1	0
methylprednisolone hemisuccinate	low	1	0
dihydrostreptomycin sulfate	low	1	0
iopydone	low	1	0
technetium	low	1	0
helium	medium	9	3
galactose	low	1	0
sodium selenite	medium	1	1
trolamine salicylate	low	2	0
cephalexin	low	2	0
cromolyn sodium	medium	5	2
tetradecanoylphorbol acetate	low	1	0
phenyl acetate	medium	13	3
sisomicin	low	1	0
tobramycin	low	1	0
substance p	low	1	0
ribavirin	medium	50	8
propiconazole	low	1	0
xenon radioisotopes	low	1	0
clarithromycin	medium	2	1
vinblastine	low	1	0
heliox	medium	7	2
methotrexate	low	2	0
sulbactam	low	1	0
benzofurans	low	1	0
lanatosides	low	1	0
n-formylmethionine leucyl-phenylalanine	low	1	0
sultamicillin	low	1	0
arachidonic acid	low	1	0
retinol	medium	1	1
tacrolimus	low	1	0
zithromax	medium	8	4
prostaglandin d2	low	1	0
glycosides	low	1	0
cotinine	low	2	0
ovalbumin	low	1	0
dinoprostone	low	1	0
dinoprost	low	1	0
leukotriene b4	low	2	0
leukotriene c4	low	1	0
leukotriene e4	low	1	0
pulmicort	medium	4	3
montelukast	medium	13	3
15-keto-13,14-dihydroprostaglandin f2alpha	low	1	0
thromboxane b2	low	1	0
phenylephrine hydrochloride	medium	6	1
fluticasone	medium	3	2
cytochalasin b	low	1	0
brevetoxin t17	low	1	0
cysteine	low	5	0
selenium	low	1	0
beta-escin	low	1	0
sq-23377	low	1	0
mocetinostat	low	2	0
fenicoberan	low	1	0
pituitrin	low	1	0
phosphatidylcholines	low	1	0
sodium ethylxanthate	low	1	0
interleukin-8	medium	25	3
natriuretic peptide, brain	low	1	0
tetracycline	low	1	0
oxytetracycline, anhydrous	low	3	0
transforming growth factor beta	low	1	0
rome	low	1	0
agar	low	1	0
spironolactone, althiazide drug combination	low	1	0
t-2 toxin	low	1	0
exudates	low	1	0
acyclovir	medium	1	1
folic acid	low	1	0
ganciclovir	medium	1	1
alcian blue	low	1	0

Protein Targets (921)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
IDH1	11	0	0	11
chromobox protein homolog 1	13	0	0	13
geminin	28	0	0	28
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, 2-oxoglutarate Oxygenase	8	0	0	8
Chain A, ATP-DEPENDENT DNA HELICASE Q1	5	0	0	5
acetylcholinesterase	4	0	0	4
dopamine D1 receptor	4	0	0	4
15-lipoxygenase, partial	4	0	0	4
pregnane X receptor	7	0	0	7
phosphopantetheinyl transferase	12	0	0	12
RAR-related orphan receptor gamma	17	0	0	17
USP1 protein, partial	13	0	0	13
NFKB1 protein, partial	4	0	0	4
Microtubule-associated protein tau	12	0	0	12
Thrombopoietin	4	0	0	4
AR protein	28	0	0	28
regulator of G-protein signaling 4	11	0	0	11
glucocorticoid receptor [Homo sapiens]	23	0	0	23
retinoic acid nuclear receptor alpha variant 1	20	0	0	20
retinoid X nuclear receptor alpha	21	0	0	21
farnesoid X nuclear receptor	14	0	0	14
estrogen nuclear receptor alpha	30	0	0	30
vitamin D (1,25- dihydroxyvitamin D3) receptor	15	0	0	15
arylsulfatase A	13	0	0	13
euchromatic histone-lysine N-methyltransferase 2	26	0	0	26
Bloom syndrome protein isoform 1	8	0	0	8
D(1A) dopamine receptor	5	0	0	5
thyroid hormone receptor beta isoform a	8	0	0	8
thyroid hormone receptor beta isoform 2	21	0	0	21
heat shock protein beta-1	4	0	0	4
flap endonuclease 1	9	0	0	9
peripheral myelin protein 22	14	0	0	14
survival motor neuron protein isoform d	8	0	0	8
muscarinic acetylcholine receptor M1	4	0	0	4
Histone deacetylase 3	0	3	0	3
Solute carrier family 22 member 6	0	5	0	6
Histone deacetylase 4	0	2	0	2
Guanine nucleotide-binding protein G	4	0	0	4
Histone deacetylase 1	0	3	0	3
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
Ataxin-2	14	0	0	14
Histone deacetylase 8	0	2	0	2
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
ATP-dependent phosphofructokinase	11	0	0	11
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	6	0	0	6
Chain B, HADH2 protein	6	0	0	6
Chain A, Ferritin light chain	6	0	0	6
Thymidine kinase	0	2	0	2
thioredoxin reductase	23	0	0	23
GLS protein	14	0	0	14
TDP1 protein	28	0	0	28
Smad3	5	0	0	5
thyroid stimulating hormone receptor	11	0	0	11
EWS/FLI fusion protein	11	0	0	11
activating transcription factor 6	10	0	0	10
Histone H2A.x	8	0	0	8
hemoglobin subunit beta	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
lamin isoform A-delta10	17	0	0	17
Solute carrier family 22 member 1	0	1	0	6
ATP-binding cassette sub-family C member 3	0	26	0	26
Multidrug resistance-associated protein 4	0	26	0	29
Bile salt export pump	0	8	0	8
Bile salt export pump	0	40	0	40
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	2
Cytochrome P450 2C9	0	5	0	5
Cytochrome P450 2J2	0	5	0	5
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Purine nucleoside phosphorylase	0	0	2	2
Solute carrier family 22 member 6	0	0	0	5
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	6
Canalicular multispecific organic anion transporter 1	0	25	0	25
Thymidine kinase	0	1	0	1
glp-1 receptor, partial	15	0	0	15
estrogen-related nuclear receptor alpha	28	0	0	28
NPYLR7B	0	0	3	3
thyroid stimulating hormone receptor	10	0	0	10
Beta-2 adrenergic receptor	0	8	10	19
Beta-1 adrenergic receptor	0	4	6	10
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-3 adrenergic receptor	0	5	5	10
Delta-type opioid receptor	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	4	0	4
Thiosulfate sulfurtransferase	0	4	0	4
Beta-2 adrenergic receptor	0	1	4	9
60 kDa chaperonin	0	4	0	4
10 kDa chaperonin	0	4	0	4
Beta-2 adrenergic receptor	0	2	5	8
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	13	0	0	13
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Beta-lactamase	9	0	0	9
Chain A, Cruzipain	4	0	0	4
Beta-lactamase	0	0	0	2
acid sphingomyelinase	4	0	0	4
GLI family zinc finger 3	24	0	0	24
apical membrane antigen 1, AMA1	3	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Metallo-beta-lactamase type 2	0	0	0	2
Metallo-beta-lactamase VIM-11	0	0	0	2
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	1	0	3
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
DNA polymerase beta	4	0	0	4
DNA polymerase eta isoform 1	3	0	0	3
DNA polymerase iota isoform a (long)	11	0	0	11
DNA polymerase kappa isoform 1	7	0	0	7
Carbonic anhydrase 1	0	4	0	6
Carbonic anhydrase 2	0	4	1	8
Beta-lactamase OXA-7	0	0	0	2
Solute carrier family 15 member 1	0	6	0	6
Solute carrier family 15 member 1	0	2	0	2
Spike glycoprotein	7	0	1	8
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Solute carrier family 15 member 2	0	4	0	4
Metallo-beta-lactamase VIM-13	0	0	0	2
Efflux transporter	0	1	0	3
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	1	0	3
Class D beta-lactamase	0	1	0	3
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	4	0	5
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	2
Metallo-b-lactamase	0	0	0	4
Carbapenem-hydrolyzing beta-lactamase KPC	0	1	0	3
Histamine H3 receptor	0	1	0	2
Beta-lactamase class B VIM-2	0	0	0	4
Beta-lactamase VIM-1	0	0	0	2
ATAD5 protein, partial	4	0	0	4
neuropeptide S receptor isoform A	2	0	0	2
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	7	0	0	7
thioredoxin glutathione reductase	5	0	0	5
aldehyde dehydrogenase 1 family, member A1	16	0	0	16
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
cellular tumor antigen p53 isoform a	4	0	0	4
vitamin D3 receptor isoform VDRA	15	0	0	15
nuclear receptor ROR-gamma isoform 1	9	0	0	9
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
cytochrome P450 3A4 isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	4	0	0	4
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	2	0	0	2
caspase-1 isoform alpha precursor	3	0	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	7	1	1	9
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Prostaglandin G/H synthase 1	0	1	0	2
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
Aromatase	0	1	0	1
Tissue factor	0	1	0	1
Fatty acid-binding protein, adipocyte	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	7	1	1	9
Gamma-aminobutyric acid receptor subunit delta	7	1	1	9
Gamma-aminobutyric acid receptor subunit gamma-2	7	1	1	9
Gamma-aminobutyric acid receptor subunit alpha-5	7	1	1	9
Gamma-aminobutyric acid receptor subunit alpha-3	7	1	1	9
Gamma-aminobutyric acid receptor subunit gamma-1	7	1	1	9
Gamma-aminobutyric acid receptor subunit alpha-2	7	1	1	9
Gamma-aminobutyric acid receptor subunit alpha-4	7	1	1	9
Gamma-aminobutyric acid receptor subunit gamma-3	7	1	1	9
Gamma-aminobutyric acid receptor subunit alpha-6	7	1	1	9
Prostaglandin G/H synthase 2	0	2	1	4
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Histamine H2 receptor	3	0	2	5
Calmodulin	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	7	1	1	9
Gamma-aminobutyric acid receptor subunit beta-3	7	1	1	9
Gamma-aminobutyric acid receptor subunit beta-2	7	1	1	9
Prostaglandin G/H synthase 2	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	3	0	7
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Lanosterol 14-alpha demethylase	0	2	0	2
GABA theta subunit	7	1	1	9
Gamma-aminobutyric acid receptor subunit epsilon	7	1	1	9
Solute carrier organic anion transporter family member 1B3	0	3	0	4
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	4	0	4
progesterone receptor	11	0	0	11
cytochrome P450 family 3 subfamily A polypeptide 4	14	0	0	14
pregnane X nuclear receptor	16	0	0	16
aryl hydrocarbon receptor	8	0	0	8
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	12	0	0	12
nuclear receptor subfamily 1, group I, member 2	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
galanin receptor type 3	0	2	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	22	0	0	22
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Glucocorticoid receptor	0	12	4	21
Glycine receptor subunit alpha-1	0	12	0	12
Glutamate receptor 2	8	0	0	8
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Cytochrome P450 2D6	0	3	0	3
Sodium-dependent serotonin transporter	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	5	0	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
mitogen-activated protein kinase 1	6	0	0	6
Interferon beta	9	0	0	9
B2 metallo-beta-lactamase	0	0	0	2
Solute carrier family 22 member 8	0	2	0	3
peroxisome proliferator-activated receptor delta	11	0	0	11
interleukin 8	5	0	0	5
G	5	0	0	5
cytochrome P450 2D6	8	0	0	8
peroxisome proliferator activated receptor gamma	13	0	0	13
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
streptokinase A precursor	0	0	5	5
lethal factor (plasmid)	4	0	0	4
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
30S ribosomal protein S6	0	4	1	5
30S ribosomal protein S7	0	4	1	5
50S ribosomal protein L15	0	4	1	5
Cellular tumor antigen p53	17	0	0	17
Cytochrome P450 3A4	0	10	1	11
50S ribosomal protein L10	0	4	1	5
50S ribosomal protein L11	0	4	1	5
50S ribosomal protein L7/L12	0	4	1	5
50S ribosomal protein L19	0	4	1	5
50S ribosomal protein L1	0	4	1	5
50S ribosomal protein L20	0	4	1	5
50S ribosomal protein L27	0	4	1	5
50S ribosomal protein L28	0	4	1	5
50S ribosomal protein L29	0	4	1	5
50S ribosomal protein L31	0	4	1	5
50S ribosomal protein L31 type B	0	4	1	5
50S ribosomal protein L32	0	4	1	5
50S ribosomal protein L33	0	4	1	5
50S ribosomal protein L34	0	4	1	5
50S ribosomal protein L35	0	4	1	5
50S ribosomal protein L36	0	4	1	5
30S ribosomal protein S10	0	4	1	5
30S ribosomal protein S11	0	4	1	5
30S ribosomal protein S12	0	4	1	5
30S ribosomal protein S13	0	4	1	5
30S ribosomal protein S16	0	4	1	5
30S ribosomal protein S18	0	4	1	5
30S ribosomal protein S19	0	4	1	5
30S ribosomal protein S20	0	4	1	5
30S ribosomal protein S2	0	4	1	5
30S ribosomal protein S3	0	4	1	5
30S ribosomal protein S4	0	4	1	5
30S ribosomal protein S5	0	4	1	5
30S ribosomal protein S8	0	4	1	5
30S ribosomal protein S9	0	4	1	5
50S ribosomal protein L13	0	4	1	5
50S ribosomal protein L14	0	4	1	5
50S ribosomal protein L16	0	4	1	5
50S ribosomal protein L23	0	4	1	5
30S ribosomal protein S15	0	4	1	5
50S ribosomal protein L17	0	4	1	5
50S ribosomal protein L21	0	4	1	5
50S ribosomal protein L30	0	4	1	5
50S ribosomal protein L6	0	4	1	5
30S ribosomal protein S14	0	4	1	5
30S ribosomal protein S17	0	4	1	5
30S ribosomal protein S1	0	4	1	5
50S ribosomal protein L18	0	4	1	5
50S ribosomal protein L2	0	4	1	5
50S ribosomal protein L3	0	4	1	5
50S ribosomal protein L24	0	4	1	5
50S ribosomal protein L4	0	4	1	5
50S ribosomal protein L22	0	4	1	5
50S ribosomal protein L5	0	4	1	5
30S ribosomal protein S21	0	4	1	5
50S ribosomal protein L25	0	4	1	5
50S ribosomal protein L36 2	0	4	1	5
Inositol hexakisphosphate kinase 1	5	0	0	5
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	5	0	0	5
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Histamine H1 receptor	0	4	2	6
MBT domain-containing protein 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Solute carrier family 22 member 1	0	2	0	3
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
ATP-dependent translocase ABCB1	0	7	0	8
Beta-lactamase	0	2	0	3
Solute carrier family 22 member 8	0	2	0	3
Beta-lactamase TEM	0	4	0	5
Luciferase	3	0	0	3
endonuclease IV	3	0	0	3
PAX8	0	0	0	2
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
Fumarate hydratase	2	0	0	2
PPM1D protein	4	0	0	4
estrogen receptor 2 (ER beta)	12	0	0	12
nuclear receptor subfamily 1, group I, member 3	12	0	0	12
polyprotein	2	0	0	2
67.9K protein	6	0	0	6
glucocerebrosidase	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	11	0	0	11
cytochrome P450 2D6 isoform 1	2	0	0	2
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C19 precursor	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
ras-related protein Rab-9A	3	0	0	3
steroidogenic factor 1	0	1	0	1
muscleblind-like protein 1 isoform 1	4	0	0	4
Solute carrier family 22 member 3	0	2	0	3
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	2
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	0	1
ATP-dependent translocase ABCB1	0	3	0	3
Nuclear receptor ROR-gamma	6	0	0	6
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
ATPase family AAA domain-containing protein 5	9	0	0	9
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
GALC protein	4	0	0	4
Cytochrome P450 1A2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	2	1	1	4
Cytochrome P450 2A6	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	1	1	4
Cytochrome P450 2A5	0	1	0	1
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	1	2	3
Carbonic anhydrase 4	0	3	0	5
Carbonic anhydrase 15	0	2	0	3
PINK1	1	0	0	1
Parkin	1	0	0	1
neutrophil cytosol factor 1	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 3	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	2	0	2
Solute carrier family 22 member 2	0	1	0	4
Prostaglandin G/H synthase 2	0	1	0	1
Thromboxane A2 receptor	0	1	1	2
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	3	2	5
Prostaglandin E2 receptor EP4 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	2	0	2
Prostaglandin F2-alpha receptor	0	2	2	4
Prostaglandin E2 receptor EP3 subtype	0	3	2	5
Prostaglandin E2 receptor EP2 subtype	0	3	1	4
Prostaglandin F2-alpha receptor	0	0	1	1
Prostacyclin receptor	0	3	1	4
Prostaglandin D2 receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
Solute carrier organic anion transporter family member 2A1	0	2	0	6
Solute carrier organic anion transporter family member 2A1	0	2	0	2
Solute carrier organic anion transporter family member 2B1	0	1	0	2
Solute carrier family 22 member 11	0	0	0	4
Solute carrier family 22 member 7	0	0	0	3
SMAD family member 2	6	0	0	6
SMAD family member 3	6	0	0	6
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
eyes absent homolog 2 isoform a	1	0	0	1
Alpha-synuclein	2	2	0	4
Inositol monophosphatase 1	2	0	0	2
TAR DNA-binding protein 43	6	0	0	6
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
Motilin receptor	0	1	1	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Albumin	0	1	2	3
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Multidrug and toxin extrusion protein 1	0	4	0	4
Chain A, Dihydrofolate reductase	0	0	1	1
alpha-galactosidase	3	0	0	3
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
thyrotropin-releasing hormone receptor	2	0	0	2
Carbonic anhydrase 12	0	1	0	3
Carbonic anhydrase 3	0	1	0	2
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Carbonic anhydrase 6	0	1	0	3
Serum paraoxonase/arylesterase 1	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	3
Carbonic anhydrase 7	0	1	0	3
Adenosine receptor A1	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	2	0	2
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Sodium/bile acid cotransporter	0	2	0	2
Carbonic anhydrase 9	0	1	0	3
Carbonic anhydrase 13	0	1	0	3
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
Carbonic anhydrase 14	0	1	0	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	3
Carbonic anhydrase 5B, mitochondrial	0	1	0	3
ClpP	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
Transitional endoplasmic reticulum ATPase	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	1	2	3
Adenosine receptor A1	0	2	0	4
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	1	0	4
Histamine H1 receptor	0	1	3	4
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Glutamate receptor ionotropic, NMDA 1	0	2	1	4
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	0	0	2
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	2	1	4
Glutamate receptor ionotropic, NMDA 2B	0	2	1	4
Glutamate receptor ionotropic, NMDA 2C	0	2	1	5
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	2	1	4
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	1	4
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	1	4
Histamine H3 receptor	0	1	2	3
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Amino acid transporter	0	1	0	1
beta-2 adrenergic receptor	6	0	0	6
hexokinase-4 isoform 1	3	0	0	3
glucokinase regulatory protein	3	0	0	3
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	2	0	0	2
Beta-1 adrenergic receptor	0	1	2	5
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Beta-2 adrenergic receptor	0	4	1	6
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
D(2) dopamine receptor	0	2	1	3
Alpha-1B adrenergic receptor	0	7	1	8
Beta-1 adrenergic receptor	0	6	2	10
Beta-2 adrenergic receptor	0	0	1	1
Alpha-2B adrenergic receptor	0	3	1	4
D(1A) dopamine receptor	0	2	1	3
D(4) dopamine receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	3	1	4
Alpha-2A adrenergic receptor	0	3	1	4
Alpha-1D adrenergic receptor	0	5	1	6
Beta-adrenergic receptor kinase 1	0	0	4	4
Alpha-1D adrenergic receptor	0	0	2	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	3	1	4
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	2	1	3
Alpha-1A adrenergic receptor	0	2	4	7
Alpha-1B adrenergic receptor	0	1	3	5
D(3) dopamine receptor	0	3	0	3
Alpha-1A adrenergic receptor	0	7	1	8
D(1A) dopamine receptor	1	0	0	1
Beta-2 adrenergic receptor	0	2	0	2
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Integrin beta-3	2	0	0	2
Integrin alpha-IIb	2	0	0	2
Leukotriene B4 receptor 1	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Cysteinyl leukotriene receptor 2	0	1	2	3
Cysteinyl leukotriene receptor 1	0	2	3	5
Canalicular multispecific organic anion transporter 1	0	2	0	3
P2Y purinoceptor 12	0	1	1	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
transcriptional regulator ERG isoform 3	3	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
M-phase phosphoprotein 8	1	0	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	0	0	1
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Protein-arginine deiminase type-4	0	5	0	5
nonstructural protein 1	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Androgen receptor	0	7	0	8
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Cytochrome P450 2C19	0	3	0	3
Nuclear receptor corepressor 2	0	1	0	1
Epidermal growth factor receptor	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Alpha-2A adrenergic receptor	0	4	3	8
Adenosine receptor A3	0	5	1	6
Cytochrome P450 2C8	0	2	0	2
Muscarinic acetylcholine receptor M1	0	3	1	4
Alpha-2C adrenergic receptor	0	4	3	8
Muscarinic acetylcholine receptor M3	0	3	1	4
Substance-K receptor	0	4	0	4
Sodium-dependent noradrenaline transporter	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Delta-type opioid receptor	0	3	1	4
5-hydroxytryptamine receptor 2B	0	4	1	5
Sodium-dependent dopamine transporter	0	2	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Mitogen-activated protein kinase 14	0	1	0	1
Leukotriene C4 synthase	0	1	0	1
Cysteinyl leukotriene receptor 1	0	1	0	1
Formyl peptide receptor-related sequence 1	0	0	1	1
fMet-Leu-Phe receptor	0	2	2	4
N-formyl peptide receptor 2	0	0	2	2
FML2_HUMAN	0	0	1	1
Atrial natriuretic peptide receptor 1	0	1	0	1
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase 1	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	1	0	2
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Kappa-type opioid receptor	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Muscarinic acetylcholine receptor M1	0	0	1	1
Muscarinic acetylcholine receptor M3	0	0	1	1
Muscarinic acetylcholine receptor M4	0	0	1	1
Muscarinic acetylcholine receptor M5	0	0	1	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	2
Cytochrome P450 2B6	0	1	0	1
Sodium-dependent serotonin transporter	0	3	0	3
Muscarinic acetylcholine receptor M4	0	0	1	2
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	0	0	1
Cholinesterase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Alpha-1B adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-2B adrenergic receptor	0	1	1	3
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	2	0	0	2
5-hydroxytryptamine receptor 2A	0	0	1	1
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	5	1	6
Progesterone receptor	0	5	1	7
Glucocorticoid receptor	0	2	1	3
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	5	2	8
Androgen receptor	0	4	1	5
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	4	1	5
heat shock protein HSP 90-alpha isoform 2	0	1	0	2
heat shock protein 90, putative	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Muscarinic acetylcholine receptor M2	0	2	1	3
5-hydroxytryptamine receptor 1A	0	2	0	2
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	1	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Endothelin-1 receptor	0	1	1	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 2A	0	2	1	3
5-hydroxytryptamine receptor 2C	0	2	1	3
5-hydroxytryptamine receptor 1B	0	2	0	2
Adenosine receptor A2a	0	4	3	8
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
Cholecystokinin receptor type A	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Mu-type opioid receptor	0	1	1	2
Vasopressin V1a receptor	0	1	1	2
Kappa-type opioid receptor	0	1	1	2
5-hydroxytryptamine receptor 6	0	2	1	3
5-hydroxytryptamine receptor 7	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium channel protein type 5 subunit alpha	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Interleukin-5	0	1	0	1
Interleukin-5	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Interleukin-5 receptor subunit alpha	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Amyloid-beta precursor protein	0	1	0	1
NS5	0	0	1	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Procathepsin L	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	2	1	3
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	3	1	6
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Angiotensin-converting enzyme 2	0	0	1	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Chain A, Mineralocorticoid receptor	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-P receptor	0	1	0	1
Substance-K receptor	0	1	0	1
D(2) dopamine receptor	0	0	1	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase OXA-1	0	1	0	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Cytochrome P450 3A5	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Stromelysin-1	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
Serine/threonine-protein kinase D3	0	0	1	1
Protein kinase C gamma type	0	1	1	2
Protein kinase C beta type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Protein kinase C alpha type	0	1	1	2
Protein kinase C eta type	0	0	1	1
Protein kinase C iota type	0	0	1	1
Protein kinase C epsilon type	0	1	1	2
Protein kinase C theta type	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	1	1	2
Serine/threonine-protein kinase D1	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Potassium channel subfamily K member 2	0	0	1	1
Renin	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A1	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	1	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Protein Rev	0	0	1	1
Endolysin	0	0	1	1
Acetylcholinesterase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Studies (363)

Protein Targets (921)

Bronchiolitis, Viral

Synonyms(1)

Research Excerpts

Overview

Actions

Research

Studies (363)

Drugs Studied (135)

Protein Targets (921)