Impetigo

A common superficial bacterial infection caused by STAPHYLOCOCCUS AUREUS or group A beta-hemolytic streptococci. Characteristics include pustular lesions that rupture and discharge a thin, amber-colored fluid that dries and forms a crust. This condition is commonly located on the face, especially about the mouth and nose.

Synonym
Impetigo

Excerpt	Reference
"Impetigo is common in the diaper area, particularly in the first 6 months of life and during the warmer summer season."	( Rasmussen, JE, 1987)
"Nonbullous impetigo is a common skin infection in children and is frequently caused by Staphylococcus aureus."	( Koning, S; Nouwen, J; Op 't Veld, M; Snijders, S; van Belkum, A; van der Wouden, JC; van Leeuwen, W; van Suijlekom-Smit, LW; Verbrugh, H; Verduin, C, 2003)
"Impetigo is a common clinical problem seen in general practice."	( George, A; Rubin, G, 2003)
"Impetigo is a contagious superficial pyogenic infection of the skin caused by Staphylococcus aureus and/or by group A Streptococcus."	( Arvanitis, A; Nasiopoulou, A; Rallis, E; Tsiambas, E, 2004)
"However, bullous impetigo is invariably considered to be a staphylococcal disease."	( Chiu, CH; Hsia, SH; Lin, JJ; Wu, CT, 2007)
"Impetigo is a common skin infection, primarily caused by Staphylococcus aureus and mainly occurring in children."	( Chosidow, O; Koning, S; Oranje, AP; Scangarella, N; Singh, KP; Twynholm, M; van der Wouden, JC, 2008)
"The hepetiformis impetigo is a pustulosis dermatosis."	( Abdelmaksoud, W; Amouri, H; Bouassida, S; Boudaya, S; Ghorbel, S; Guermazi, M; Masmoudi, A; Mseddi, M; Turki, H; Zahaf, A, 2008)
"Although bullous impetigo is a common diagnosis in children and it would be tempting to make that diagnosis in the presence of a positive skin swab culture, clinicians always have to be mindful of secondary impetiginization of another primary skin disease process."	( Alsharqi, A; Parslew, R; Shukla, R, 2010)
"Impetigo is a highly contagious bacterial skin infection affecting children worldwide that is caused by the Gram-positive bacteria Staphylococcus aureus, Streptococcus pyogenes, or both."	( Anderson, M; Blanco, DM; Celeri, C; Debabov, D; Fernández, JA; Iovino, SM; Khosrovi, B; Krantz, KD; Memarzadeh, B; Najafi, A; Ocampo, N, 2011)
"Impetigo is a common, superficial bacterial skin infection, which is most frequently encountered in children."	( Berger, M; Butler, CC; Koning, S; Morris, AD; van der Sande, R; van der Wouden, JC; van Suijlekom-Smit, LW; Verhagen, AP, 2012)
"Impetigo is caused by both Streptococcus pyogenes and Staphylococcus aureus; the relative contributions of each have been reported to fluctuate with time and region."	( Bowen, AC; Carapetis, JR; Chatfield, MD; Tong, SY, 2014)
"Bullous impetigo is caused by Staphylococcus aureus toxins that break down intercellular proteins."	( Boute, FJ; Loots, MA; Molenaar-Hoogendijk, M, 2016)
"Impetigo is the most common bacterial skin infection in children."	( Cantón, R; García-Castillo, M; Hebert, AA; López, Y; Tato, M; Torrelo, A; Vila, J, 2019)
"Impetigo is a contagious bacterial infection that affects the superficial skin layers."	( Andriessen, A; Hebert, AA; Hohl, D; Kircik, LH; Kwong, P; Lynde, CW; Oza, V; Schachner, LA; Torrelo, A, 2021)
"Bacterial impetigo is one of the most common skin infection in childhood."	( Fortina, AB; Galli, L; Novelli, A; Ruggiero, G; Stefani, S, 2022)

Excerpt	Reference
"Impetigo affects more than 110 million children worldwide at any one time."	( Andrews, RM; Bowen, AC; Carapetis, JR; Chatfield, MD; Currie, BJ; McDonald, MI; O'Meara, IM; Tong, SY, 2014)

Excerpt	Reference
"Among the 32 sulconazole-treated impetigo patients, bacterial cultures from 26 (69%) were negative by treatment day 4, and those from all 32 (100%) were negative by treatment day 7; among the 34 miconazole-treated impetigo patients, cultures from 17 (50%) were negative by treatment day 4, cultures from 32 (94."	( Nolting, S; Strauss, WB, 1988)
"To determine the most effective treatment for impetigo in a systemically well patient."	( George, A; Rubin, G, 2003)
"Sulfonamides can be used in the treatment of impetigo with vastly increased safety and with more effectiveness in powder rather than ointment form when combined with urea powder in a ratio of approximately three parts of sulfonamide to one of urea."	( HAMLIN, EM; McGINLEY, JP; REES, RB, 1952)
"Advertisements claim that the product "treats localised impetigo in just 5 days"; by comparison, the British National Formulary (BNF) advises a 7-day course of fusidic acid."	( , 2008)
"To assess the effects of treatments for impetigo, including non-pharmacological interventions and 'waiting for natural resolution'."	( Berger, M; Butler, CC; Koning, S; Morris, AD; van der Sande, R; van der Wouden, JC; van Suijlekom-Smit, LW; Verhagen, AP, 2012)
"Topical treatment for impetigo includes amongst other bacitracin, gentamycin, mupirocin, retapamulin, and more recently, ozenoxacin 1% cream."	( Andriessen, A; Bhatia, N; Grada, A; Patele, D; Schachner, L, 2019)
"The study aimed to improve the treatment of impetigo with naturally occurring quercetin and its copper-quercetin (Cu-Q) complex by preparing sustained-release (SR) nanoparticles of polycaprolactone (PCL)."	( Abbas, G; Ahmed, N; Aziz, M; Hanif, M; Khan, WS; Mahmood, K; Ramzan, N; Rasul, S; Sami Ullah, M; Shah, S; Usman, M; Uzair, M, 2023)
"Ozenoxacin is a new antibiotic used to treat non-bullous impetigo."	( Capossela, L; Chiaretti, A; Curatola, A; Di Sarno, L; Ferretti, S; Fiori, B; Gatto, A; Oliveti, A; Talamonti, D, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	215 (46.54)	23.3326
1990's	48 (10.39)	12.5806
2000's	89 (19.26)	18.1394
2010's	83 (17.97)	28.8240
2020's	27 (5.84)	9.53

Drug	Relationship Strength	Studies	Trials
acetic acid	low	1	0
hydrochloric acid	low	1	0
salicylic acid	low	2	0
dimethyl sulfoxide	low	1	0
formaldehyde	low	3	0
glycerol	low	1	0
iodine	low	1	0
endolysin	low	1	0
croton oil	low	1	0
nickel	low	1	0
niacinamide	low	1	0
taurine	medium	1	1
toluene	low	2	0
uracil	low	1	0
urea	low	3	0
1-anilino-8-naphthalenesulfonate	low	4	0
phenytoin	low	1	0
ethacridine	low	1	0
albendazole	low	1	0
aspirin	low	1	0
azathioprine	low	2	0
benzocaine	low	1	0
chloroquine	low	1	0
ciprofloxacin	low	1	0
clioquinol	low	2	0
clotrimazole	low	1	0
dapsone	low	2	0
diethylcarbamazine	low	1	0
econazole	low	2	0
etilefrine	low	1	0
gentamicin	medium	9	1
hexachlorophene	medium	12	2
hydrochlorothiazide	low	1	0
lidocaine	low	1	0
khellin	low	1	0
methoxsalen	low	1	0
metoprolol	low	1	0
metronidazole	low	1	0
miconazole	medium	2	2
ofloxacin	low	2	0
oxolinic acid	low	1	0
procaine	low	1	0
sulfadiazine	low	1	0
sulconazole	medium	1	1
sulfamethoxazole	medium	2	1
sulfanilamide	low	3	0
sulfathiazole	low	1	0
gatifloxacin	low	1	0
triclosan	low	2	0
trimethoprim	medium	2	1
prednisolone	medium	10	1
thyroxine	low	1	0
penicillamine	low	1	0
prednisone	low	7	0
fluprednisolone	medium	1	1
penicillin g	medium	10	2
chloramphenicol	low	11	0
sucrose	low	1	0
ethinyl estradiol	low	1	0
aminopyrine	low	2	0
cephalothin	medium	3	1
kanamycin a	low	4	0
carbostyril	medium	18	5
methicillin	low	6	0
cloxacillin	medium	8	1
methylene blue	low	1	0
lactose	medium	1	1
oxacillin	low	5	0
fluocinolone acetonide	low	2	0
ampicillin	medium	12	1
mestranol	low	1	0
tryptophan	low	1	0
isoleucine	low	1	0
trichloroacetic acid	low	1	0
triamcinolone acetonide	low	2	0
methylprednisolone	low	1	0
lawsone	low	1	0
penicillin v	medium	6	3
n-vinyl-2-pyrrolidinone	low	2	0
propylparaben	low	1	0
methylparaben	low	1	0
framycetin	medium	9	1
nafcillin	low	1	0
acridines	low	1	0
thiazoles	low	1	0
ethynodiol diacetate	low	1	0
betamethasone	low	3	0
alpha-aminopyridine	medium	17	5
gentian violet	low	3	0
erythromycin	medium	44	13
levonorgestrel	low	1	0
potassium hydroxide	low	2	0
zinc oxide	low	1	0
monolaurin	low	1	0
vancomycin	low	2	0
flumethasone	medium	2	1
didecyldimethylammonium	medium	1	1
dicloxacillin	medium	8	4
fluorescein-5-isothiocyanate	low	1	0
floxacillin	low	8	0
mercury	low	3	0
gold	low	1	0
silver nitrate	low	1	0
fluorine	low	1	0
ozone	low	1	0
trolamine salicylate	low	4	0
cephalexin	medium	14	4
phenyl acetate	low	1	0
triamcinolone	low	2	0
du-21220	low	1	0
amoxicillin	medium	7	2
amikacin	low	1	0
cephradine	medium	2	2
denotivir	low	1	0
permethrin	medium	5	1
propiconazole	low	1	0
cefotiam	medium	1	1
cefadroxil anhydrous	medium	4	1
cefaclor anhydrous	low	3	0
octenidine	low	1	0
itraconazole	low	2	0
imiquimod	low	1	0
cephalosporin c	medium	12	4
arbekacin	low	1	0
oxazolidin-2-one	low	1	0
bisecurin i	low	1	0
clarithromycin	low	5	0
fibrinogen	low	2	0
fluocinolone	low	1	0
glycidyl nitrate	low	1	0
imipenem, anhydrous	low	1	0
methotrexate	low	6	0
sulbactam	low	1	0
carbapenems	medium	2	2
levofloxacin	low	2	0
paromomycin	low	1	0
depsidomycin	low	1	0
troleandomycin	low	1	0
cortisone	low	5	0
rosoxacin	low	1	0
trimethoprim, sulfamethoxazole drug combination	medium	3	2
povidone-iodine	medium	2	1
fibrin	low	2	0
inositol 3-phosphate	low	1	0
griseofulvin	low	2	0
erythromycin estolate	low	1	0
linezolid	medium	3	1
sultamicillin	low	1	0
tretinoin	low	1	0
retinol	low	2	0
oleic acid	low	1	0
tacrolimus	low	2	0
clindamycin	low	9	0
zithromax	medium	7	4
dibekacin	low	1	0
potassium permanganate	low	1	0
bromochloroacetic acid	low	1	0
glycosides	low	1	0
squalene	low	1	0
terbinafine	medium	3	1
fusidic acid	medium	45	6
lincomycin	medium	2	1
zinc oxide	low	12	0
naphthoquinones	low	1	0
sphingosine	low	1	0
quercetin	low	1	0
calcitriol	low	1	0
vitamin k semiquinone radical	low	1	0
alprostadil	low	1	0
clavulanic acid	medium	3	1
cefzil	medium	1	1
miocamycin	low	1	0
rokitamycin	low	1	0
etretinate	low	3	0
isotretinoin	low	3	0
sphingosine 1-phosphate	low	1	0
phenylephrine hydrochloride	medium	15	3
acitretin	low	1	0
cefroxadine	medium	2	2
clobetasol	low	1	0
lead	low	1	0
arsenic	low	1	0
sulfur	low	6	0
nitrofurazone	low	3	0
heroin	low	2	0
cefotaxime	medium	4	1
ammonium sulfate	low	2	0
rifamycin sv	low	1	0
selenium	low	1	0
cilastatin	low	1	0
cefpodoxime proxetil	medium	1	1
hoe 777	medium	1	1
retapamulin	medium	15	5
chlorhexidine	low	1	0
amoxicillin-potassium clavulanate combination	medium	3	1
mocetinostat	low	1	0
jte 013	low	1	0
nystatin a1	low	3	0
cefdinir	low	1	0
dextrothyroxine	medium	12	6
rifamycins	low	1	0
sy 5555	medium	2	2
chiniofon	medium	1	1
calcipotriene	low	1	0
tetracycline	medium	13	2
chlortetracycline	low	7	0
oxytetracycline, anhydrous	low	4	0
minocycline	medium	4	1
salicylates	low	4	0
demeclocycline	low	1	0
adimicin	low	1	0
calca protein, human	low	1	0
agar	low	2	0
hyaluronoglucosaminidase	low	1	0
norgestrel	low	1	0
cyclosporine	low	4	0
lactoferrin	low	1	0
exudates	low	3	0
acyclovir	low	2	0
rifampin	low	2	0
concanavalin a	low	1	0

Protein Targets (1,442)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	18	0	0	18
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	6	0	0	6
thioredoxin reductase	36	0	0	36
USP1 protein, partial	35	0	0	35
TDP1 protein	70	0	0	70
vitamin D3 receptor isoform VDRA	32	0	0	32
importin subunit beta-1 isoform 1	10	0	0	10
flap endonuclease 1	21	0	0	21
serine/threonine-protein kinase PLK1	11	0	0	11
snurportin-1	10	0	0	10
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	10	0	0	10
GTP-binding nuclear protein Ran isoform 1	4	0	0	4
DNA polymerase eta isoform 1	14	0	0	14
DNA polymerase iota isoform a (long)	31	0	0	31
urokinase-type plasminogen activator precursor	16	0	0	16
plasminogen precursor	16	0	0	16
urokinase plasminogen activator surface receptor precursor	16	0	0	16
geminin	72	0	0	72
DNA polymerase kappa isoform 1	21	0	0	21
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	0	1
Beta-lactamase	0	8	0	8
Transthyretin	0	2	2	5
Fatty acid-binding protein, intestinal	0	1	1	2
Fatty acid-binding protein, adipocyte	0	3	1	4
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	2	2	4
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	0	1
Guanine nucleotide-binding protein G	9	0	0	9
Fatty acid-binding protein 5	0	1	1	2
Fatty acid-binding protein 5	0	0	1	1
Mitogen-activated protein kinase 11	0	1	0	1
Mitogen-activated protein kinase 14	0	4	0	4
Chain A, Beta-lactamase	18	0	0	18
aldehyde dehydrogenase 1 family, member A1	41	0	0	41
IDH1	26	0	0	26
Phosphatidylinositol 4-kinase alpha	0	3	0	3
Xanthine dehydrogenase/oxidase	0	4	0	4
TAR DNA-binding protein 43	18	0	0	18
Phosphatidylinositol 4-kinase type 2-beta	0	3	0	3
Phosphatidylinositol 4-kinase type 2-alpha	0	3	0	3
Phosphatidylinositol 4-kinase beta	0	3	0	3
estrogen nuclear receptor alpha	96	0	0	96
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	2	1	3
Tyrosine-protein kinase Fyn	0	6	1	7
Fibrinogen C domain-containing protein 1	0	1	0	1
Luciferase	22	0	0	22
Microtubule-associated protein tau	31	0	0	32
AR protein	69	0	0	69
glucocorticoid receptor [Homo sapiens]	61	0	0	61
peroxisome proliferator activated receptor gamma	39	0	0	39
euchromatic histone-lysine N-methyltransferase 2	49	0	0	49
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	45	0	0	45
thyroid hormone receptor beta isoform 2	50	0	0	50
eyes absent homolog 2 isoform a	3	0	0	3
peripheral myelin protein 22	39	0	0	39
survival motor neuron protein isoform d	19	0	0	19
histone acetyltransferase KAT2A isoform 1	19	0	0	19
ATP-binding cassette sub-family C member 3	0	55	0	56
Multidrug resistance-associated protein 4	0	55	0	58
Bile salt export pump	0	20	0	20
Bile salt export pump	0	76	0	76
Rap guanine nucleotide exchange factor 3	9	0	0	9
Cellular tumor antigen p53	57	0	0	57
Rap guanine nucleotide exchange factor 4	8	0	0	8
Chain A, Ferritin light chain	20	0	0	20
Smad3	14	0	0	14
alpha-galactosidase	4	0	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	22	0	0	22
DNA topoisomerase 2-alpha	0	1	0	6
Acetylcholinesterase	0	12	0	12
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	16	0	0	16
Chain B, HADH2 protein	16	0	0	16
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Thymidine kinase	0	1	0	1
phosphopantetheinyl transferase	22	0	0	22
GLS protein	20	0	0	20
thyroid stimulating hormone receptor	24	0	0	24
EWS/FLI fusion protein	26	0	0	26
arylsulfatase A	13	0	0	13
activating transcription factor 6	30	0	0	30
Histone H2A.x	24	0	0	24
Bloom syndrome protein isoform 1	21	0	0	21
hemoglobin subunit beta	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	10	0	0	10
lamin isoform A-delta10	53	0	0	53
Solute carrier family 22 member 1	0	4	0	6
Solute carrier family 22 member 6	0	11	0	12
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	1
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	20	4	26
Cytochrome P450 2J2	0	10	0	10
Disintegrin and metalloproteinase domain-containing protein 17	7	0	0	7
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	7	0	9
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	8	0	11
Canalicular multispecific organic anion transporter 1	0	53	0	53
Thymidine kinase	0	1	0	1
glp-1 receptor, partial	18	0	0	18
hypoxia-inducible factor 1 alpha subunit	26	0	0	26
RAR-related orphan receptor gamma	54	0	0	54
ATAD5 protein, partial	20	0	0	20
Fumarate hydratase	11	0	0	11
GLI family zinc finger 3	62	0	0	62
caspase 7, apoptosis-related cysteine protease	9	0	0	9
nuclear receptor subfamily 1, group I, member 3	46	0	0	46
progesterone receptor	38	0	0	38
retinoic acid nuclear receptor alpha variant 1	58	0	0	58
retinoid X nuclear receptor alpha	51	0	0	51
estrogen-related nuclear receptor alpha	61	0	0	61
farnesoid X nuclear receptor	34	0	0	34
pregnane X nuclear receptor	55	0	0	55
polyprotein	11	0	0	11
67.9K protein	13	0	0	13
vitamin D (1,25- dihydroxyvitamin D3) receptor	36	0	0	36
caspase-3	9	0	0	9
aryl hydrocarbon receptor	37	0	0	37
v-jun sarcoma virus 17 oncogene homolog (avian)	30	0	0	30
nuclear receptor subfamily 1, group I, member 2	15	0	0	15
cellular tumor antigen p53 isoform a	10	0	0	10
chromobox protein homolog 1	36	0	0	36
nuclear factor erythroid 2-related factor 2 isoform 2	21	0	0	21
transcriptional regulator ERG isoform 3	9	0	0	9
histone deacetylase 9 isoform 3	9	0	0	9
heat shock protein beta-1	28	0	0	28
mitogen-activated protein kinase 1	20	0	0	20
Vif	0	0	0	1
muscleblind-like protein 1 isoform 1	10	0	0	10
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	3	0	0	3
neuropeptide S receptor isoform A	5	0	0	5
Voltage-dependent calcium channel gamma-2 subunit	32	0	0	32
Interferon beta	47	0	0	47
Integrin beta-3	9	1	0	10
Integrin alpha-IIb	9	1	0	10
Methionine aminopeptidase	0	1	0	1
Glutamate receptor 2	32	0	0	32
Fatty-acid amide hydrolase 1	1	3	0	4
Inositol monophosphatase 1	7	0	0	7
ATPase family AAA domain-containing protein 5	25	0	0	25
Ataxin-2	26	0	0	26
thyroid stimulating hormone receptor	31	0	0	31
Heat shock protein HSP 90-alpha	0	0	1	1
Botulinum neurotoxin type A	0	2	0	2
Neutrophil cytosol factor 1	0	2	0	2
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, brain	0	3	0	3
Nitric oxide synthase, inducible	0	1	0	1
Kappa-type opioid receptor	0	1	2	8
Mu-type opioid receptor	0	3	1	4
Tyrosine-protein kinase	0	0	1	1
Thromboxane-A synthase	0	6	0	6
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	3	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Aminoglycoside 3'-phosphotransferase	0	0	0	2
ATP-dependent phosphofructokinase	15	0	0	15
interleukin 8	13	0	0	13
15-lipoxygenase, partial	10	0	0	10
estrogen receptor 2 (ER beta)	34	0	0	34
cytochrome P450 family 3 subfamily A polypeptide 4	40	0	0	40
G	37	0	0	37
peroxisome proliferator-activated receptor delta	37	0	0	37
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	22	0	0	22
thyroid hormone receptor beta isoform a	25	0	0	25
nuclear factor erythroid 2-related factor 2 isoform 1	56	0	0	56
HLA class I histocompatibility antigen, B alpha chain	37	0	0	37
Nicotinate phosphoribosyltransferase	0	3	0	3
Inositol hexakisphosphate kinase 1	37	0	0	37
cytochrome P450 2C9, partial	37	0	0	37
ORF73	0	0	2	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	27	0	0	27
Chain A, 2-oxoglutarate Oxygenase	25	0	0	25
Beta-lactamase	0	1	0	4
Beta-lactamase	0	1	0	6
Beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	7
apical membrane antigen 1, AMA1	9	0	0	9
Beta-lactamase	0	0	0	3
Beta-lactamase SHV-1	0	1	0	5
Beta-lactamase SHV-1	0	3	0	8
Beta-lactamase	0	2	0	7
Solute carrier family 15 member 1	0	19	0	19
Solute carrier family 15 member 1	0	5	0	6
B2 metallo-beta-lactamase	0	0	0	6
Solute carrier family 15 member 2	0	12	0	12
Beta-lactamase	0	1	0	5
Beta-lactamase	0	1	0	5
Solute carrier family 15 member 2	0	12	0	13
Beta-lactamase	0	1	0	5
Beta-lactamase	0	0	0	5
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Chain A, Cruzipain	17	0	0	17
Beta-lactamase	0	1	0	5
Beta-lactamase	0	2	0	6
Beta-lactamase	0	0	0	5
Metallo-beta-lactamase type 2	0	0	0	5
Metallo-beta-lactamase VIM-11	0	0	0	5
Metallo-beta-lactamase VIM-2	0	0	0	5
Beta-lactamase	0	1	0	6
Metallo-beta-lactamase	0	0	0	5
Beta-lactamase	0	2	0	6
DNA polymerase beta	11	0	0	11
Carbonic anhydrase 1	0	13	0	16
Carbonic anhydrase 2	0	16	3	22
60 kDa heat shock protein, mitochondrial	0	8	0	8
Beta-lactamase OXA-7	0	0	0	5
Spike glycoprotein	28	1	3	32
10 kDa heat shock protein, mitochondrial	0	8	0	8
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	2	0	6
Beta-lactamase	0	2	0	6
Beta-lactamase	0	2	0	6
Thiosulfate sulfurtransferase	0	8	0	8
Metallo-beta-lactamase VIM-13	0	0	0	5
Efflux transporter	0	1	0	4
Beta-lactamase	0	0	0	4
Beta-lactamase Toho-1	0	0	0	4
Beta-lactamase	0	1	0	4
Class D beta-lactamase	0	2	0	5
60 kDa chaperonin	0	8	0	8
Metallo-beta-lactamase	0	0	0	4
Beta-lactamase	0	2	0	6
Beta-lactamase	0	0	0	3
10 kDa chaperonin	0	8	0	8
Metallo-b-lactamase	0	0	0	8
Carbapenem-hydrolyzing beta-lactamase KPC	0	3	0	8
Histamine H3 receptor	0	0	0	4
Beta-lactamase class B VIM-2	0	0	0	8
Beta-lactamase VIM-1	0	0	0	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	19	0	0	19
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	3	0	0	3
cytochrome P450 2D6	24	0	0	24
glucocerebrosidase	8	0	0	8
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
muscarinic acetylcholine receptor M1	10	0	0	10
lethal factor (plasmid)	9	0	0	9
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	7	0	7
Fatty acid-binding protein, liver	0	3	0	3
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	3	0	5
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Adenosine receptor A1	1	2	0	3
Adenosine receptor A2a	0	2	0	2
Substance-P receptor	0	3	0	3
Prostaglandin G/H synthase 2	0	8	0	8
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	16	1	1	18
Ras-related protein Rab-2A	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	23	4	1	29
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	6	1	7
Sigma non-opioid intracellular receptor 1	0	0	1	1
acetylcholinesterase	19	0	0	19
SMAD family member 2	21	0	0	21
SMAD family member 3	21	0	0	21
thioredoxin glutathione reductase	13	0	0	13
P53	2	0	0	2
peripheral myelin protein 22 isoform 1	10	0	0	10
cytochrome P450 3A4 isoform 1	23	0	0	23
M-phase phosphoprotein 8	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	23	3	1	28
Gamma-aminobutyric acid receptor subunit beta-1	23	3	1	28
Gamma-aminobutyric acid receptor subunit delta	23	3	1	28
Gamma-aminobutyric acid receptor subunit gamma-2	23	3	1	28
Gamma-aminobutyric acid receptor subunit alpha-5	23	3	1	28
Gamma-aminobutyric acid receptor subunit alpha-3	23	3	1	28
Gamma-aminobutyric acid receptor subunit gamma-1	23	3	1	28
Gamma-aminobutyric acid receptor subunit alpha-2	23	3	1	28
Gamma-aminobutyric acid receptor subunit alpha-4	23	3	1	28
Gamma-aminobutyric acid receptor subunit gamma-3	23	3	1	28
Gamma-aminobutyric acid receptor subunit alpha-6	23	3	1	28
Gamma-aminobutyric acid receptor subunit beta-3	23	3	1	28
Gamma-aminobutyric acid receptor subunit beta-2	23	3	1	28
GABA theta subunit	23	3	1	28
Gamma-aminobutyric acid receptor subunit epsilon	23	3	1	28
Protein-arginine deiminase type-4	0	11	0	11
nuclear receptor ROR-gamma isoform 1	26	0	0	26
pregnane X receptor	13	0	0	13
galanin receptor type 3	0	2	0	2
Glucocorticoid receptor	0	20	2	27
Glycine receptor subunit alpha-1	0	20	0	20
Glycine receptor subunit beta	0	20	0	20
Glycine receptor subunit alpha-2	0	20	0	20
Glycine receptor subunit alpha-3	0	20	0	20
relaxin receptor 1 isoform 1	1	0	0	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Vitamin D3 receptor	0	0	1	1
PPM1D protein	10	0	0	10
Vitamin D-binding protein	0	0	1	1
Cytochrome P450 1A2	0	10	1	13
Cytochrome P450 3A4	0	21	1	25
Androgen receptor	0	3	0	3
Cytochrome P450 2D6	0	12	1	14
Vitamin D3 receptor	0	1	2	5
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	2	5	7
Cytochrome P450 2C19	0	10	1	12
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Chain A, Putative fructose-1,6-bisphosphate aldolase	11	0	0	11
Chain A, serum paraoxonase	0	1	0	1
Carbonic anhydrase 12	0	6	0	8
Carbonic anhydrase 3	0	5	0	7
Carbonic anhydrase 4	0	6	0	8
Carbonic anhydrase 6	0	8	0	10
Carbonic anhydrase 5A, mitochondrial	0	7	0	10
Carbonic anhydrase 7	0	7	0	9
Carbonic anhydrase 9	0	9	1	12
Carbonic anhydrase 13	0	2	0	2
Poly [ADP-ribose] polymerase tankyrase-2	0	1	0	1
Carbonic anhydrase 14	0	6	0	8
Carbonic anhydrase 5B, mitochondrial	0	6	0	8
bromodomain adjacent to zinc finger domain 2B	13	0	0	13
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1	0	2	0	2
streptokinase A precursor	0	0	17	17
Estrogen receptor	0	0	8	8
Estrogen receptor beta	0	0	8	8
GALC protein	5	0	0	5
Multidrug resistance-associated protein 1	0	1	0	3
Solute carrier family 22 member 8	0	6	0	7
Beta-lactamase	0	3	0	6
Beta-lactamase	0	3	0	6
Metallo-beta-lactamase VIM-19	0	0	0	3
Beta-lactamase	0	2	0	5
Albumin	0	2	8	10
Beta-lactamase	0	0	0	2
Beta-lactamase	0	2	0	5
Metallo-beta-lactamase VIM-2	0	0	0	4
Solute carrier family 22 member 7	0	2	0	3
BlaVIM-1	0	0	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	1	0	4
Solute carrier family 22 member 11	0	2	0	4
Solute carrier family 22 member 7	0	2	0	3
endonuclease IV	8	0	0	8
WRN	2	0	0	2
DNA (cytosine-5)-methyltransferase 1 isoform b	0	1	0	1
Solute carrier family 22 member 8	0	8	0	9
Beta-lactamase	0	2	0	4
Beta-lactamase	0	3	0	6
Beta-lactamase OXA-1	0	2	0	3
Beta-lactamase TEM	0	7	0	11
Beta-lactamase	0	1	0	3
phosphoglycerate kinase	5	0	0	5
Dihydroxyacetone phosphate acyltransferase	0	0	0	2
30S ribosomal protein S6	0	7	1	8
30S ribosomal protein S7	0	7	1	8
50S ribosomal protein L15	0	7	1	8
50S ribosomal protein L10	0	7	1	8
50S ribosomal protein L11	0	7	1	8
50S ribosomal protein L7/L12	0	7	1	8
50S ribosomal protein L19	0	7	1	8
50S ribosomal protein L1	0	7	1	8
50S ribosomal protein L20	0	7	1	8
50S ribosomal protein L27	0	7	1	8
50S ribosomal protein L28	0	7	1	8
50S ribosomal protein L29	0	7	1	8
50S ribosomal protein L31	0	7	1	8
50S ribosomal protein L31 type B	0	7	1	8
50S ribosomal protein L32	0	7	1	8
50S ribosomal protein L33	0	7	1	8
50S ribosomal protein L34	0	7	1	8
50S ribosomal protein L35	0	7	1	8
50S ribosomal protein L36	0	7	1	8
30S ribosomal protein S10	0	7	1	8
30S ribosomal protein S11	0	7	1	8
30S ribosomal protein S12	0	7	1	8
30S ribosomal protein S13	0	7	1	8
30S ribosomal protein S16	0	7	1	8
30S ribosomal protein S18	0	7	1	8
30S ribosomal protein S19	0	7	1	8
30S ribosomal protein S20	0	7	1	8
30S ribosomal protein S2	0	7	1	8
30S ribosomal protein S3	0	7	1	8
30S ribosomal protein S4	0	7	1	8
30S ribosomal protein S5	0	7	1	8
30S ribosomal protein S8	0	7	1	8
30S ribosomal protein S9	0	7	1	8
50S ribosomal protein L13	0	7	1	8
50S ribosomal protein L14	0	7	1	8
50S ribosomal protein L16	0	7	1	8
50S ribosomal protein L23	0	7	1	8
30S ribosomal protein S15	0	7	1	8
50S ribosomal protein L17	0	7	1	8
50S ribosomal protein L21	0	7	1	8
50S ribosomal protein L30	0	7	1	8
50S ribosomal protein L6	0	7	1	8
30S ribosomal protein S14	0	7	1	8
30S ribosomal protein S17	0	7	1	8
30S ribosomal protein S1	0	7	1	8
50S ribosomal protein L18	0	7	1	8
50S ribosomal protein L2	0	7	1	8
50S ribosomal protein L3	0	7	1	8
50S ribosomal protein L24	0	7	1	8
50S ribosomal protein L4	0	7	1	8
50S ribosomal protein L22	0	7	1	8
50S ribosomal protein L5	0	7	1	8
30S ribosomal protein S21	0	7	1	8
50S ribosomal protein L25	0	7	1	8
50S ribosomal protein L36 2	0	7	1	8
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	2	2
PAX8	0	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	17	0	0	17
PINK1	4	0	0	4
Parkin	7	0	0	7
heat shock protein 90	0	0	4	4
calcineurin A1, putative	0	0	2	2
cytochrome P450 2D6 isoform 1	9	0	0	9
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
cytochrome P450 2C19 precursor	9	0	0	9
cytochrome P450 2C9 precursor	9	0	0	9
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	16	0	0	16
huntingtin isoform 2	8	0	0	8
ubiquitin-conjugating enzyme E2 N	0	2	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	4	0	0	4
protein AF-9 isoform a	0	0	0	2
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	2
bcl-2-related protein A1	0	2	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
bcl-2-like protein 11 isoform 1	0	0	2	2
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	1	0	10
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Glutathione reductase, mitochondrial	0	3	0	5
72 kDa type IV collagenase	0	3	0	3
Matrix metalloproteinase-9	0	4	0	4
Trypanothione reductase	0	1	0	1
Alpha-synuclein	7	5	0	12
Histamine H2 receptor	14	0	0	14
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Multidrug and toxin extrusion protein 1	0	6	0	6
Spermine oxidase	0	1	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	2	3	5
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
Transmembrane protease serine 2	0	1	3	4
Dihydrofolate reductase	0	4	0	4
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Major prion protein	0	0	1	1
Amyloid-beta precursor protein	0	6	0	6
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	1	3	4
Muscarinic acetylcholine receptor M2	0	12	0	12
Muscarinic acetylcholine receptor M4	0	12	0	12
Muscarinic acetylcholine receptor M5	0	6	0	6
Alpha-2A adrenergic receptor	0	17	0	17
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	6	3	9
Spike glycoprotein	0	2	1	3
Replicase polyprotein 1ab	0	8	4	12
Muscarinic acetylcholine receptor M1	0	12	0	12
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	0	1
Alpha-2B adrenergic receptor	0	14	0	14
Alpha-2C adrenergic receptor	0	8	0	8
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	12	0	12
Serine/threonine-protein kinase mTOR	0	2	0	2
Beta-secretase 1	0	4	0	4
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	1	0	1
DNA ligase A	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	16	0	17
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	1	3	4
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
P2Y purinoceptor 12	0	2	0	2
Beta-2 adrenergic receptor	0	2	0	2
Beta-1 adrenergic receptor	0	2	1	3
Dipeptidase 1	0	1	0	1
Beta-3 adrenergic receptor	0	1	1	2
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	3
DNA gyrase subunit A	0	5	0	8
DNA gyrase subunit B	0	5	0	8
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	3
DNA topoisomerase 4 subunit A	0	2	0	4
DNA gyrase subunit A	0	1	0	3
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	3	0	4
DNA gyrase subunit A	0	5	0	6
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	3	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
Integrase	0	4	0	4
ATP-dependent translocase ABCB1	0	13	1	17
Solute carrier organic anion transporter family member 1B3	0	6	0	8
Solute carrier organic anion transporter family member 1B1	0	8	0	10
Beta-lactamase	0	2	0	2
Neutrophil elastase	0	3	0	3
Cytochrome P450 2B6	0	2	1	3
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
mu opioid receptor, partial	0	0	1	1
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
regulator of G-protein signaling 4	11	0	0	11
nonstructural protein 1	7	0	0	7
LAP4	0	0	1	1
MEP2	0	0	1	1
polyunsaturated fatty acid lipoxygenase ALOX12	6	0	0	6
delta-type opioid receptor	0	1	1	2
kappa-type opioid receptor isoform 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	11	0	0	11
heat shock protein HSP 90-alpha isoform 2	0	2	0	8
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Histone deacetylase 3	0	3	0	3
Alpha-1B adrenergic receptor	0	22	1	23
Catechol O-methyltransferase	0	1	0	1
Alpha-1D adrenergic receptor	0	4	1	5
Alpha-1A adrenergic receptor	0	21	1	22
Histone deacetylase 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Histone deacetylase 1	0	3	0	3
Beta-galactosidase	0	0	1	1
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	3	0	3
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	2	0	2
Carbonic anhydrase 15	0	3	0	4
Histone deacetylase 8	0	2	0	2
Carbonic anhydrase 13	0	5	0	7
Histone deacetylase 6	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	6
mitogen-activated protein kinase kinase kinase kinase 2 isoform 1	0	0	1	1
mitogen-activated protein kinase kinase kinase 3 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 1A	0	12	2	14
Cruzipain	0	2	0	2
C-terminal-binding protein 1	1	0	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	1	7
NFKB1 protein, partial	4	0	0	4
Thrombopoietin	1	0	0	1
isocitrate dehydrogenase 1, partial	2	0	0	2
pyruvate kinase	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
thyrotropin-releasing hormone receptor	6	0	0	6
Caspase-7	7	0	0	7
beta-2 adrenergic receptor	1	0	1	2
caspase-3	7	0	0	7
ras-related protein Rab-9A	2	0	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Intermediate conductance calcium-activated potassium channel protein 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
5-hydroxytryptamine receptor 4	0	10	0	10
Transient receptor potential cation channel subfamily M member 2	0	2	0	2
Chymotrypsinogen A	0	5	0	5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	4	0	4
Steroid 17-alpha-hydroxylase/17,20 lyase	0	4	0	4
Heme oxygenase 1	0	5	0	5
ATP-dependent translocase ABCB1	0	7	0	7
Epoxide hydrolase 1	0	0	0	2
Aldo-keto reductase family 1 member B1	0	15	0	15
Beta-1 adrenergic receptor	0	8	1	9
Adenosine receptor A3	0	19	0	19
Aromatase	0	4	0	4
Beta-3 adrenergic receptor	0	6	1	7
D(2) dopamine receptor	0	8	0	8
Androgen receptor	0	21	0	21
Potassium-transporting ATPase subunit beta	0	1	0	1
Potassium-transporting ATPase alpha chain 1	0	1	0	1
ATP-dependent translocase ABCB1	0	7	0	7
Substance-K receptor	0	12	0	12
D(1A) dopamine receptor	0	8	0	8
D(4) dopamine receptor	0	7	0	7
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Heme oxygenase 2	0	5	0	5
Sodium-dependent noradrenaline transporter	0	14	2	16
Histamine H2 receptor	0	10	0	10
C-X-C chemokine receptor type 1	0	2	0	2
Alpha-1D adrenergic receptor	0	12	0	12
Substance-P receptor	0	6	0	6
Platelet-activating factor receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	10	0	10
5-hydroxytryptamine receptor 2C	0	10	0	10
5-hydroxytryptamine receptor 1B	0	6	0	6
Indoleamine 2,3-dioxygenase 1	0	5	0	5
Adenosine receptor A2a	0	14	0	14
Vasopressin V2 receptor	0	2	0	2
Adenosine receptor A1	0	6	0	6
Sodium-dependent serotonin transporter	0	15	1	16
Histamine H1 receptor	0	2	0	2
Mu-type opioid receptor	0	10	0	10
D(3) dopamine receptor	0	10	0	10
Malate dehydrogenase, cytoplasmic	0	4	0	4
Delta-type opioid receptor	0	6	0	6
Kappa-type opioid receptor	0	10	0	10
5-hydroxytryptamine receptor 2B	0	14	0	14
5-hydroxytryptamine receptor 6	0	7	0	7
C-C chemokine receptor type 4	0	2	0	2
Transitional endoplasmic reticulum ATPase	0	1	0	1
Cytochrome P450 144	0	0	4	4
Steroid C26-monooxygenase	0	0	4	4
Cytochrome P450 130	0	0	2	2
Cytochrome P450 130	0	0	2	2
Steroid C26-monooxygenase	0	0	4	4
Mycocyclosin synthase	0	0	3	3
Lanosterol 14-alpha demethylase	0	0	3	3
Sodium-dependent dopamine transporter	0	12	0	12
Voltage-dependent L-type calcium channel subunit alpha-1C	0	5	0	5
Nuclear receptor subfamily 1 group I member 3	0	3	0	3
Lanosterol 14-alpha demethylase	0	7	0	7
Sterol 14-alpha demethylase	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	5	0	5
Bile acid receptor	0	3	0	3
14-alpha sterol demethylase	0	0	1	1
Cysteinyl leukotriene receptor 1	0	2	0	2
dopamine D1 receptor	4	0	0	4
Sex hormone-binding globulin	0	0	2	2
Corticosteroid-binding globulin	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Dihydrofolate reductase	0	6	0	7
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	4	0	4
Acetylcholinesterase	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	5	0	6
Cannabinoid receptor 1	0	6	0	6
Melanocortin receptor 5	0	4	0	4
Melanocortin receptor 3	0	4	0	4
Neuropeptide Y receptor type 2	0	2	0	2
Cholinesterase	0	2	0	2
Calcium release-activated calcium channel protein 1	0	2	0	2
Motilin receptor	0	0	1	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
Motilin receptor	0	1	1	2
60 kDa chaperonin	0	5	0	5
Chitinase B	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Cytochrome P450 1B1	0	4	1	5
NPYLR7B	0	0	1	1
Telomerase reverse transcriptase	0	1	0	1
Coagulation factor XII	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Vpr	7	0	0	7
Cytochrome P450 2B1	0	1	0	1
Estrogen receptor	0	6	1	7
Neuronal acetylcholine receptor subunit alpha-4	3	0	0	3
Neuronal acetylcholine receptor subunit beta-2	3	0	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
UDP-glucuronosyltransferase 1A1	0	2	0	3
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Sulfotransferase 1A1	0	2	1	4
Aldehyde oxidase	0	1	0	1
Estrogen receptor beta	0	3	1	4
Amine oxidase [flavin-containing] A	0	6	0	6
D(3) dopamine receptor isoform e	1	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
Lethal factor	0	1	0	1
Protein Rev	0	0	1	1
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Chain A, Type Iii Chloramphenicol Acetyltransferase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	3
large T antigen	0	2	0	2
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]	1	0	0	1
alpha synuclein, partial	1	0	0	1
luciferase	2	0	0	2
tumor necrosis factor	2	0	0	2
Glutamate receptor ionotropic, kainate 1	1	0	0	1
Glutamate receptor ionotropic, kainate 2	1	0	0	1
Glutamate receptor ionotropic, kainate 3	1	0	0	1
Glutamate receptor ionotropic, kainate 4	1	0	0	1
Leukotriene B4 receptor 1	1	0	0	1
Glutamate receptor ionotropic, kainate 5	1	0	0	1
Leukotriene B4 receptor 2	1	0	0	1
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
calpain II, partial	0	1	0	1
SUMO-1	0	1	0	1
Mcl-1	0	1	0	1
Valosin-containing protein	0	2	0	2
TSHR protein	2	0	0	2
Estrogen receptor 1	0	1	0	1
envelope glycoprotein	0	1	0	1
heat shock 70kDa protein 1A	0	1	0	1
galactokinase	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
neuropeptide Y receptor type 1	0	0	1	1
neuropeptide Y receptor type 2	0	0	1	1
small ubiquitin-related modifier 2 isoform b precursor	0	1	0	1
estrogen receptor beta isoform 1	0	2	0	2
enteropeptidase precursor	1	0	0	1
fatty acid synthase	0	1	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	2	0	2
heat shock cognate 71 kDa protein isoform 1	0	1	0	1
eukaryotic translation initiation factor 4E isoform 1	0	2	0	2
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase	1	0	0	1
replicative DNA helicase	0	0	0	2
recombinase A	0	0	2	2
exodeoxyribonuclease V subunit RecD	0	3	0	3
exodeoxyribonuclease V subunit RecB	0	3	0	3
exodeoxyribonuclease V subunit RecC	0	3	0	3
POsterior Segregation	0	0	2	2
heat shock cognate 71 kDa protein isoform 2	0	1	0	1
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Endoplasmic reticulum chaperone BiP	0	2	0	2
Macrophage migration inhibitory factor	0	2	0	2
Mitogen-activated protein kinase 3	0	1	0	1
Mitogen-activated protein kinase 1	0	3	0	3
Caspase-7	2	0	0	2
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
M1-family alanyl aminopeptidase	0	1	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
BZLF2	0	1	0	1
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase, alpha family	0	3	0	3
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase	0	2	0	2
Hsf1 protein	0	0	1	1
Carbonic anhydrase	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	3	0	3
Carbonic anhydrase	0	2	0	2
Delta carbonic anhydrase	0	2	0	2
Genome polyprotein	0	1	0	1
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	1	2
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	2
Beta-lactamase	0	0	0	2
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Proton-coupled amino acid transporter 1	0	2	0	2
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
Olfactory receptor 51E2	0	1	1	2
Sphingosine 1-phosphate receptor 2	0	2	2	5
Sphingosine 1-phosphate receptor 4	0	2	1	3
Sphingosine 1-phosphate receptor 1	0	2	1	3
Sphingosine 1-phosphate receptor 2	0	1	0	1
Sphingosine 1-phosphate receptor 3	0	2	1	3
Sphingosine 1-phosphate receptor 5	0	2	1	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Cytochrome P450 1A1	0	4	1	5
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, Lectin	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, ERYTHRINA CRISTA-GALLI LECTIN	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, cellulase	0	0	1	1
Chain A, Galectin-3	0	0	1	1
Chain A, Anti-tumor lectin	0	1	0	1
Galectin-3	0	1	0	1
Galectin-9	0	0	1	1
Galectin-8	0	0	1	1
Beta-galactoside-binding lectin	0	1	0	1
Galectin-1	0	1	1	3
Galectin-3	0	1	1	2
Galectin-3	0	1	1	3
Galectin-7	0	0	1	1
Alpha 1,4 galactosyltransferase	0	0	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Genome polyprotein	0	1	0	1
Protease	0	2	1	3
Histone-lysine N-methyltransferase SETD7	0	1	0	1
Cysteine protease	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 22	0	1	0	1
P2X purinoceptor 7	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
Tubulin beta-4A chain	0	1	0	1
Tubulin beta chain	0	1	0	1
Tubulin alpha-3C chain	0	1	0	1
Tubulin alpha-1B chain	0	1	0	1
Tubulin alpha-4A chain	0	1	0	1
Tubulin beta-4B chain	0	1	0	1
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	1	0	1
Tubulin beta-2A chain	0	1	0	1
Tubulin beta-8 chain	0	1	0	1
Tubulin alpha-3E chain	0	1	0	1
Tubulin alpha-1A chain	0	1	0	1
Tubulin alpha-1C chain	0	1	0	1
Tubulin beta-6 chain	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Tubulin beta-1 chain	0	1	0	1
Progesterone receptor	0	2	1	4
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	3
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Serum paraoxonase/arylesterase 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Renin	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
caspase-1 isoform alpha precursor	1	0	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	6	0	7
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	4	0	5
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Thymidylate synthase	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	3
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	3	0	3
Thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	4	2	6
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	5	0	5
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Dihydrofolate reductase	0	2	0	2
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Dihydrofolate reductase	0	2	0	3
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Polyphenol oxidase 2	0	2	1	5
Cytochrome P450 2A6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
integrase, partial	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
lens epithelium-derived growth factor p75	0	1	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
serine-protein kinase ATM isoform a	3	0	0	3
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	2	0	0	2
Albumin	0	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	1	1	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Beta-1 adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Metabotropic glutamate receptor 6	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Aromatase	0	0	1	1
Melanocortin receptor 4	0	2	0	2
Type-2 angiotensin II receptor	0	2	0	2
methionyl-tRNA synthetase, putative	0	1	0	1
Stromelysin-1	0	4	1	5
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Isoleucyl-tRNA synthetase	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	3
Isoleucine--tRNA ligase	0	1	0	1
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	2	0	2
Poly [ADP-ribose] polymerase 1	0	1	0	1
Tissue factor	0	2	0	2
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
NAD(+) hydrolase SARM1	0	3	0	3
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Metabotropic glutamate receptor 5	0	2	0	2
Snake venom metalloproteinase BaP1	0	1	0	1
STE24	0	0	0	1
Trypsin	0	1	0	2
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
putative potassium channel subunit	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Fatty acid-binding protein, liver	0	0	1	1
DNA topoisomerase 1	0	1	0	1
Protein kinase C alpha type	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	3	0	5
Sterol O-acyltransferase 1	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	0	0	1
Peroxisome proliferator-activated receptor alpha	1	0	1	2
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
MecA	0	1	0	1
microphthalmia-associated transcription factor isoform 9	0	1	0	1
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
luciferase	0	0	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
Nrf2	1	0	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
DNA polymerase III, partial	1	0	0	1
Neuraminidase	0	2	0	2
hexokinase	0	1	0	1
interferon gamma precursor	0	0	0	1
D(1A) dopamine receptor	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
NUAK family SNF1-like kinase 1	0	1	0	1
Lysine-specific histone demethylase 1A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
G2/mitotic-specific cyclin-B2	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	1	2
Prothrombin	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Interstitial collagenase	0	1	1	2
Phospholipase A2	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Tyrosine-protein kinase Yes	0	1	0	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	0	1
Insulin-like growth factor 1 receptor	0	1	0	1
Hepatocyte growth factor receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	0	1	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	2	0	2
Calmodulin-1	0	1	0	1
Alpha-amylase 1A	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sialidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	1	2
Cyclin-dependent kinase 4	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Sucrase-isomaltase, intestinal	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Tyrosinase	0	1	0	1
Urease subunit alpha	0	3	0	3
Serine/threonine-protein kinase B-raf	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	0	1
5'-nucleotidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
G1/S-specific cyclin-D1	0	1	0	1
Dipeptidyl peptidase 4	0	2	0	2
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Proteasome subunit beta type-5	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Bifunctional epoxide hydrolase 2	0	2	0	2
Trypsin-3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	1	0	1
Macrophage metalloelastase	0	1	0	1
Glutathione reductase	0	1	0	1
Tyrosine-protein kinase SYK	0	1	1	2
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	1
Glycogen synthase kinase-3 alpha	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Serine/threonine-protein kinase PLK1	0	1	0	1
Death-associated protein kinase 1	0	1	0	1
Mitogen-activated protein kinase 10	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	0	2
Urease subunit beta	0	3	0	3
Lactoperoxidase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	0	4
Cyclin-dependent kinase 6	0	1	0	1
Cyclin-dependent-like kinase 5	0	1	0	1
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Focal adhesion kinase 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	0	1
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Substance-K receptor	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Enoyl-acyl-carrier protein reductase	0	4	0	4
3-oxoacyl-acyl-carrier protein reductase	0	1	0	1
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	1	0	1
Aurora kinase B	0	1	0	1
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
G-protein coupled receptor 35	0	1	1	2
Serine/threonine-protein kinase Nek6	0	1	0	1
NADPH oxidase 4	0	1	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	1
Dipeptidyl peptidase 3	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	0	1
Sialidase-2	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Solute carrier organic anion transporter family member 2B1	0	3	0	3
NH(3)-dependent NAD(+) synthetase	0	2	0	2
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	2
Solute carrier organic anion transporter family member 1A2	0	2	0	3
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
B-cell lymphoma 6 protein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Protein kinase C eta type	0	1	0	1
Sphingosine kinase 2	0	1	0	1
Sphingosine kinase 1	0	1	0	1
Protein kinase C theta type	0	1	0	1
Squalene monooxygenase	0	1	0	2
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Metallo-beta-lactamase type 2	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Aurora kinase A	0	1	0	1
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	2	0	2
Endothelin-1 receptor	0	2	0	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2	0	1	1	2
Cholinesterase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 4	0	1	0	1
Protein argonaute-2	0	0	1	1
Transcriptional activator protein LasR	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Protein arginine N-methyltransferase 6	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
C-8 sterol isomerase	0	1	0	1
Squalene monooxygenase	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
Neutrophil collagenase	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	2	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Cysteine protease ATG4A	0	1	0	1
Cysteine protease ATG4B	0	1	0	1
Endolysin	0	0	1	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	2	4
Nuclear receptor ROR-alpha	0	1	0	1
Retinoic acid receptor RXR-gamma	0	2	2	4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
NLRP3 protein	0	1	0	1
Epoxide hydrolase B	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, Repressor	0	0	1	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Carbonyl reductase [NADPH] 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	0	2	0	2
Enoyl-acyl carrier reductase	0	1	0	1
Enoyl-ACP reductase II	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Plasma kallikrein	0	0	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Tryprostatin B synthase	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Studies (462)

Protein Targets (1,442)

Impetigo

Synonyms(1)

Research Excerpts

Overview

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Treatment

Research

Studies (462)

Drugs Studied (245)

Protein Targets (1,442)