Tongue, Hairy

A benign condition of the tongue characterized by hypertrophy of the filiform papillae that give the dorsum of the tongue a furry appearance. The color of the elongated papillae varies from yellowish white to brown or black, depending upon staining by substances such as tobacco, food, or drugs. (Dorland, 27th ed)

Synonym
Tongue, Hairy

Excerpt	Reference
"Black hairy tongue is the name given to the appearance of an abnormal coating of the tongue and occurs only in adults."	( Carr, MM; Ive, FA; Langtry, JA; Steele, MC, 1992)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	17 (32.69)	23.3326
1990's	5 (9.62)	12.5806
2000's	4 (7.69)	18.1394
2010's	19 (36.54)	28.8240
2020's	7 (13.46)	9.53

Drug	Relationship Strength	Studies
acetone	low	1
nicotine 1-n-oxide	low	1
niacin	low	4
dequalinium	low	1
fluconazole	low	3
fluoxetine	low	1
lansoprazole	low	1
lorazepam	low	1
metronidazole	low	2
triclosan	low	1
prednisone	low	1
methionine	low	1
triamcinolone acetonide	low	1
penicillanic acid	low	1
n-vinyl-2-pyrrolidinone	low	1
phenothiazine	low	1
podophyllotoxin	low	1
triamcinolone	low	1
zidovudine	low	1
piperacillin	low	1
cephalosporin c	low	1
clarithromycin	low	1
nicotine	low	2
hydroxycotinine	low	1
cotinine-n-oxide	low	1
levofloxacin	low	1
moxifloxacin	low	1
cotinine n-glucuronide	low	1
povidone-iodine	low	1
linezolid	low	6
tretinoin	low	4
sodium bicarbonate	low	1
bromochloroacetic acid	low	1
flavin-adenine dinucleotide	low	1
cotinine	low	1
ranitidine	low	1
nicotine n-glucuronide	low	1
clavulanic acid	low	1
bismuth	low	2
amoxicillin-potassium clavulanate combination	low	1
nystatin a1	low	1
podophyllin	low	1
bismuth subsalicylate	low	1
cilastatin, imipenem drug combination	low	1
piperacillin, tazobactam drug combination	low	1
tetracycline	low	1
chlortetracycline	low	2
minocycline	low	3
salicylates	low	2
bismuth salicylate	low	1
exudates	low	1
olanzapine	low	1

Protein Targets (743)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
TDP1 protein	18	0	0	18
glucocorticoid receptor [Homo sapiens]	12	0	0	12
estrogen-related nuclear receptor alpha	15	0	0	15
thyroid hormone receptor beta isoform 2	13	0	0	13
lamin isoform A-delta10	17	0	0	17
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	6	0	0	6
Luciferase	5	0	0	5
euchromatic histone-lysine N-methyltransferase 2	14	0	0	14
Spike glycoprotein	8	0	0	8
RAR-related orphan receptor gamma	13	0	0	13
AR protein	15	0	0	15
aldehyde dehydrogenase 1 family, member A1	9	0	0	9
nuclear receptor subfamily 1, group I, member 3	10	0	0	10
retinoic acid nuclear receptor alpha variant 1	14	0	0	14
thyroid stimulating hormone receptor	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	12	0	0	12
Cellular tumor antigen p53	12	0	0	12
Nuclear receptor ROR-gamma	3	1	1	5
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	4	0	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
acetylcholinesterase	5	0	0	5
phosphopantetheinyl transferase	5	0	0	5
estrogen receptor 2 (ER beta)	8	0	0	8
G	8	0	0	8
cytochrome P450 2D6	7	0	0	7
vitamin D3 receptor isoform VDRA	7	0	0	7
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
DNA polymerase kappa isoform 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	4	0	0	4
Interferon beta	10	0	0	10
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
Inositol hexakisphosphate kinase 1	8	0	0	8
cytochrome P450 2C9, partial	8	0	0	8
ATP-dependent phosphofructokinase	7	0	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
P2Y purinoceptor 12	0	2	0	2
Protein-arginine deiminase type-4	0	5	0	5
GLI family zinc finger 3	17	0	0	17
cytochrome P450 family 3 subfamily A polypeptide 4	12	0	0	12
estrogen nuclear receptor alpha	21	0	0	21
importin subunit beta-1 isoform 1	1	0	0	1
mitogen-activated protein kinase 1	3	0	0	3
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
geminin	15	0	0	15
streptokinase A precursor	0	0	3	3
ATP-binding cassette sub-family C member 3	0	14	0	14
Multidrug resistance-associated protein 4	0	14	0	14
Bile salt export pump	0	18	0	18
ATP-dependent translocase ABCB1	0	4	0	6
Cytochrome P450 3A4	0	9	1	11
Potassium voltage-gated channel subfamily H member 2	0	9	0	10
Canalicular multispecific organic anion transporter 1	0	14	0	14
Solute carrier organic anion transporter family member 1B3	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Bile salt export pump	0	2	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	2	0	2
Beta-lactamase	0	1	0	1
Neutrophil elastase	0	1	0	1
Beta-lactamase SHV-1	0	1	0	2
Beta-lactamase SHV-1	0	2	0	3
Beta-lactamase OXA-1	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase TEM	0	2	0	3
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	2
Class D beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	2
Metallo-b-lactamase	0	0	0	2
Beta-lactamase	0	1	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	2	0	3
Beta-lactamase class B VIM-2	0	0	0	2
ATAD5 protein, partial	6	0	0	6
GALC protein	1	0	0	1
regulator of G-protein signaling 4	6	0	0	6
flap endonuclease 1	2	0	0	2
Cytochrome P450 1A2	0	4	1	6
Neuronal acetylcholine receptor subunit alpha-4	2	3	3	9
Cytochrome P450 2A6	0	3	1	4
Neuronal acetylcholine receptor subunit beta-2	2	3	3	9
Cytochrome P450 2A5	0	2	0	2
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Cruzipain	2	0	0	2
thioredoxin reductase	8	0	0	8
15-lipoxygenase, partial	3	0	0	3
Fumarate hydratase	2	0	0	2
USP1 protein, partial	7	0	0	7
Microtubule-associated protein tau	7	0	0	7
Thrombopoietin	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
thyroid stimulating hormone receptor	4	0	0	4
polyprotein	2	0	0	2
arylsulfatase A	3	0	0	3
cytochrome P450 2D6 isoform 1	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	4	0	0	4
cellular tumor antigen p53 isoform a	1	0	0	1
D(1A) dopamine receptor	3	0	0	3
chromobox protein homolog 1	12	0	0	12
huntingtin isoform 2	2	0	0	2
ras-related protein Rab-9A	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
nuclear receptor ROR-gamma isoform 1	7	0	0	7
peripheral myelin protein 22	7	0	0	7
survival motor neuron protein isoform d	3	0	0	3
cytochrome P450 3A4 isoform 1	7	0	0	7
M-phase phosphoprotein 8	3	0	0	3
muscarinic acetylcholine receptor M1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	7	0	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
Amyloid-beta precursor protein	2	2	0	4
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Gamma-aminobutyric acid receptor subunit beta-1	7	0	0	7
Gamma-aminobutyric acid receptor subunit delta	7	0	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-5	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	7	0	0	7
Gamma-aminobutyric acid receptor subunit gamma-1	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-4	7	0	0	7
Gamma-aminobutyric acid receptor subunit gamma-3	7	0	0	7
Gamma-aminobutyric acid receptor subunit alpha-6	7	0	0	7
Alpha-synuclein	3	4	0	7
Histamine H2 receptor	3	0	0	3
D(1A) dopamine receptor	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	7	0	0	7
Gamma-aminobutyric acid receptor subunit beta-3	7	0	0	7
Gamma-aminobutyric acid receptor subunit beta-2	7	0	0	7
Inositol monophosphatase 1	3	0	0	3
GABA theta subunit	7	0	0	7
Ataxin-2	9	0	0	9
Gamma-aminobutyric acid receptor subunit epsilon	7	0	0	7
Single-stranded DNA cytosine deaminase	1	0	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
apical membrane antigen 1, AMA1	3	0	0	3
retinoid X nuclear receptor alpha	10	0	0	10
pregnane X nuclear receptor	14	0	0	14
unnamed protein product	0	1	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	3
DNA polymerase iota isoform a (long)	6	0	0	6
bcl-2-like protein 11 isoform 1	0	0	1	1
Histone deacetylase 3	0	1	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Chymotrypsinogen A	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Heme oxygenase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	1	2
Aromatase	0	1	0	1
Cytochrome P450 2C9	0	9	2	12
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Heme oxygenase 2	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Histone deacetylase 4	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
TAR DNA-binding protein 43	5	0	0	5
Histone deacetylase 1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	1	3
Sterol 14-alpha demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	1	2
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
14-alpha sterol demethylase	0	0	1	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
heat shock protein 90, putative	0	0	0	2
likely tRNA 2'-phosphotransferase	0	1	0	1
caspase 7, apoptosis-related cysteine protease	3	0	0	3
progesterone receptor	9	0	0	9
peroxisome proliferator-activated receptor delta	7	0	0	7
peroxisome proliferator activated receptor gamma	6	0	0	6
caspase-3	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	8	0	0	8
Histone H2A.x	5	0	0	5
Caspase-7	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
caspase-3	4	0	0	4
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	6	0	6
Voltage-dependent calcium channel gamma-2 subunit	6	0	0	6
Potassium channel subfamily K member 2	0	1	0	1
Albumin	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Aldo-keto reductase family 1 member B1	0	4	0	4
5-hydroxytryptamine receptor 2C	0	4	0	4
Muscarinic acetylcholine receptor M5	0	4	0	4
Alpha-2A adrenergic receptor	0	3	0	3
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2D6	0	3	1	5
Muscarinic acetylcholine receptor M1	0	3	1	4
Angiotensin-converting enzyme	0	3	0	3
Dipeptidyl peptidase 4	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Alpha-1B adrenergic receptor	0	8	0	8
Alpha-2B adrenergic receptor	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Glutamate receptor 2	6	0	0	6
Muscarinic acetylcholine receptor M3	0	4	0	4
Acetylcholinesterase	0	1	0	1
Alpha-2C adrenergic receptor	0	2	0	2
Acetylcholinesterase	0	1	0	1
Alpha-2A adrenergic receptor	0	2	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Alpha-1D adrenergic receptor	0	5	0	5
Sodium-dependent noradrenaline transporter	0	5	1	6
Sodium-dependent dopamine transporter	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	0	4
5-hydroxytryptamine receptor 2C	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Sodium-dependent serotonin transporter	0	4	2	6
Sodium-dependent serotonin transporter	0	2	0	2
Cytochrome P450 2C19	0	4	1	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Alpha-1A adrenergic receptor	0	8	0	8
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
5-hydroxytryptamine receptor 6	0	4	0	4
Cytochrome P450 2J2	0	5	0	5
D(2) dopamine receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Sodium-dependent dopamine transporter	0	4	1	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Sodium-dependent serotonin transporter	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Transporter	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	3	0	3
Beta-2 adrenergic receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	3	1	5
Histamine H3 receptor	0	1	0	1
Chain A, Beta-lactamase	5	0	0	5
Chain A, JmjC domain-containing histone demethylation protein 3A	4	0	0	4
GLS protein	6	0	0	6
EWS/FLI fusion protein	7	0	0	7
Parkin	3	0	0	3
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
alpha-galactosidase	2	0	0	2
aryl hydrocarbon receptor	10	0	0	10
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
Replicase polyprotein 1ab	0	2	0	2
lysosomal alpha-glucosidase preproprotein	4	0	0	4
peripheral myelin protein 22 isoform 1	2	0	0	2
cytochrome P450 2C19 precursor	2	0	0	2
cytochrome P450 2C9 precursor	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
phosphoethanolamine/phosphocholine phosphatase isoform 1	0	1	0	1
heat shock protein beta-1	5	0	0	5
serine/threonine-protein kinase PLK1	2	0	0	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Replicase polyprotein 1ab	0	3	0	3
Microtubule-associated protein tau	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	1	0	0	1
Fatty acid synthase	0	3	0	3
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
CAAX prenyl protease 2 isoform 2	0	0	0	1
DNA polymerase beta	2	0	0	2
Tubulin beta-4A chain	0	2	1	4
Tubulin beta chain	0	2	1	4
Tubulin alpha-3C chain	0	2	1	4
Tubulin alpha-1B chain	0	2	1	4
Tubulin alpha-4A chain	0	2	1	4
Tubulin beta-4B chain	0	2	1	4
Fatty-acid amide hydrolase 1	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA primase	0	1	0	1
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	2	1	4
Tubulin beta-8 chain	0	2	1	4
Tubulin alpha-3E chain	0	2	1	4
Tubulin alpha-1A chain	0	2	1	4
Multidrug and toxin extrusion protein 1	0	2	0	2
Tubulin alpha-1C chain	0	2	1	4
Tubulin beta-6 chain	0	2	1	4
Tubulin beta-2B chain	0	2	1	4
Tubulin beta-1 chain	0	2	1	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
30S ribosomal protein S6	0	2	0	2
30S ribosomal protein S7	0	2	0	2
50S ribosomal protein L15	0	2	0	2
Estrogen receptor	0	0	1	1
50S ribosomal protein L10	0	2	0	2
50S ribosomal protein L11	0	2	0	2
50S ribosomal protein L7/L12	0	2	0	2
50S ribosomal protein L19	0	2	0	2
50S ribosomal protein L1	0	2	0	2
50S ribosomal protein L20	0	2	0	2
50S ribosomal protein L27	0	2	0	2
50S ribosomal protein L28	0	2	0	2
50S ribosomal protein L29	0	2	0	2
50S ribosomal protein L31	0	2	0	2
50S ribosomal protein L31 type B	0	2	0	2
50S ribosomal protein L32	0	2	0	2
50S ribosomal protein L33	0	2	0	2
50S ribosomal protein L34	0	2	0	2
50S ribosomal protein L35	0	2	0	2
50S ribosomal protein L36	0	2	0	2
30S ribosomal protein S10	0	2	0	2
30S ribosomal protein S11	0	2	0	2
30S ribosomal protein S12	0	2	0	2
30S ribosomal protein S13	0	2	0	2
30S ribosomal protein S16	0	2	0	2
30S ribosomal protein S18	0	2	0	2
30S ribosomal protein S19	0	2	0	2
30S ribosomal protein S20	0	2	0	2
30S ribosomal protein S2	0	2	0	2
30S ribosomal protein S3	0	2	0	2
30S ribosomal protein S4	0	2	0	2
30S ribosomal protein S5	0	2	0	2
30S ribosomal protein S8	0	2	0	2
30S ribosomal protein S9	0	2	0	2
50S ribosomal protein L13	0	2	0	2
50S ribosomal protein L14	0	2	0	2
50S ribosomal protein L16	0	2	0	2
50S ribosomal protein L23	0	2	0	2
30S ribosomal protein S15	0	2	0	2
DNA gyrase subunit A	0	3	0	4
DNA gyrase subunit B	0	3	0	4
50S ribosomal protein L17	0	2	0	2
50S ribosomal protein L21	0	2	0	2
50S ribosomal protein L30	0	2	0	2
50S ribosomal protein L6	0	2	0	2
30S ribosomal protein S14	0	2	0	2
30S ribosomal protein S17	0	2	0	2
30S ribosomal protein S1	0	2	0	2
50S ribosomal protein L18	0	2	0	2
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	3	0	3
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
50S ribosomal protein L2	0	2	0	2
50S ribosomal protein L3	0	2	0	2
50S ribosomal protein L24	0	2	0	2
50S ribosomal protein L4	0	2	0	2
50S ribosomal protein L22	0	2	0	2
50S ribosomal protein L5	0	2	0	2
30S ribosomal protein S21	0	2	0	2
50S ribosomal protein L25	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
50S ribosomal protein L36 2	0	2	0	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Estrogen receptor beta	0	0	1	1
Renin	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Translocator protein	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Thioredoxin reductase	0	1	0	1
thyroid hormone receptor beta isoform a	3	0	0	3
muscleblind-like protein 1 isoform 1	3	0	0	3
Flavodoxin	0	0	0	1
Albumin	0	0	2	2
Stromelysin-1	0	2	0	2
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Replicase polyprotein 1ab	0	2	0	2
DNA topoisomerase 2-alpha	0	0	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
DNA gyrase subunit B	0	1	0	2
Sodium channel protein type 5 subunit alpha	0	1	0	1
activating transcription factor 6	5	0	0	5
glp-1 receptor, partial	3	0	0	3
thyrotropin-releasing hormone receptor	3	0	0	3
Polyphenol oxidase 2	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
5-hydroxytryptamine receptor 3E	0	2	0	2
interleukin 8	2	0	0	2
hypoxia-inducible factor 1 alpha subunit	6	0	0	6
Smad3	3	0	0	3
Solute carrier family 22 member 1	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	2	5
Acetylcholine receptor subunit gamma	0	2	1	3
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	2	2	5
Neuronal acetylcholine receptor subunit beta-3	0	2	2	5
Neuronal acetylcholine receptor subunit beta-4	0	2	2	5
Translocator protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-5	0	2	2	5
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Muscarinic acetylcholine receptor M4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-6	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-9	0	2	2	5
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Mu-type opioid receptor	0	1	0	1
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	5
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Solute carrier family 22 member 1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-10	0	2	2	5
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
5-hydroxytryptamine receptor 1A	0	1	1	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
D	0	1	0	1
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Adenosine receptor A1	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
D(4) dopamine receptor	0	1	0	1
Histamine H1 receptor	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Histamine H1 receptor	0	2	1	3
Alpha-1B adrenergic receptor	0	1	0	1
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 2B	0	4	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Vpr	2	0	0	2
Rap guanine nucleotide exchange factor 4	1	0	0	1
NADPH oxidase 1	0	1	0	1
farnesoid X nuclear receptor	5	0	0	5
Snq2p	0	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
rac GTPase-activating protein 1 isoform a	0	1	0	1
lethal factor (plasmid)	2	0	0	2
Adenosine receptor A3	0	4	0	4
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Pleiotropic ABC efflux transporter of multiple drugs	0	1	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase OXA-7	0	0	0	1
Kappa-type opioid receptor	0	0	0	1
Solute carrier family 15 member 1	0	1	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
PAX8	0	0	0	1
SMAD family member 2	5	0	0	5
PPM1D protein	1	0	0	1
SMAD family member 3	5	0	0	5
67.9K protein	1	0	0	1
IDH1	3	0	0	3
nuclear receptor subfamily 0 group B member 1	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	6	0	0	6
steroidogenic factor 1	0	1	0	1
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Regulatory protein E2	0	0	1	1
Regulatory protein E2	0	0	1	1
Regulatory protein E2	0	0	1	1
Glucocorticoid receptor	0	9	2	16
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Calcium-activated potassium channel subunit alpha-1	0	1	0	1
Tubulin beta-2B chain	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
ATPase family AAA domain-containing protein 5	6	0	0	6
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	8	0	8
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
pregnane X receptor	2	0	0	2
thioredoxin glutathione reductase	3	0	0	3
NFKB1 protein, partial	2	0	0	2
Carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Histamine H4 receptor	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
72 kDa type IV collagenase	0	1	0	1
Neutrophil collagenase	0	1	0	1
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Integrase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	2
Solute carrier family 22 member 11	0	0	0	2
Solute carrier family 22 member 7	0	0	0	2
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Chain A, Ferritin light chain	2	0	0	2
nonstructural protein 1	1	0	0	1
Bloom syndrome protein isoform 1	2	0	0	2
Ornithine decarboxylase	0	0	0	1
Ornithine decarboxylase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
60 kDa heat shock protein, mitochondrial	0	1	0	1
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
10 kDa heat shock protein, mitochondrial	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, Repressor	0	0	1	1
PINK1	1	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Transthyretin	0	1	1	2
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Endoplasmic reticulum chaperone BiP	0	1	0	1
Carbonyl reductase [NADPH] 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	0	2	0	2
Enoyl-acyl carrier reductase	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
Enoyl-ACP reductase II	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
Ectonucleoside triphosphate diphosphohydrolase 1	0	0	0	1
Solute carrier family 22 member 6	0	0	0	1
Thymidine kinase, cytosolic	0	2	0	3
Protein kinase C beta type	0	1	0	1
DNA polymerase beta	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Thymidine kinase, cytosolic	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Thymidylate kinase	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Thymidine kinase	0	1	0	2
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Reverse transcriptase/RNaseH	0	1	2	6
Protease	0	1	1	2
Thymidine kinase	0	1	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Research

Studies (52)

Protein Targets (743)

Tongue, Hairy

Synonyms(1)

Research Excerpts

Overview

Research

Studies (52)

Drugs Studied (59)

Protein Targets (743)