Page last updated: 2024-08-05 11:32:33

11-oxo steroid

Any oxo steroid that has an oxo substituent at position 11.

ChEBI ID: 47787

Members (11)

MemberDefinitionRole
11-dehydrocorticosteroneAn 11-oxo steroid that is corticosterone in which the hydroxy substituent at the 11beta position has been oxidised to give the corresponding ketone.11-dehydrocorticosterone
11-ketotestosteroneA 3-oxo Delta(4)-steroid that is testosterone carrying an additional oxo substituent at position 11.11-oxotestosterone
3alpha-hydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a hydroxy group at position 3, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic, anticholinergic and antiserotonergic activities.zhankuic acid B
3alpha,12alpha-dihydroxy-4alpha-methylergosta-8,24(28)-dien-7,11-dione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by hydroxy groups at positions 3 and 12, a methyl group at position 4 and oxo groups at positions 7 and 11 (the 3alpha,4alpha,5alpha,12alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits antineoplastic activity.zhankuic acid C
4alpha-methylergosta-8,24(28)-dien-3,7,11-trione-26-oic acidA steroid acid that is ergosta-8,24(28)-dien-26-oic acid substituted by a methyl group at position 4 and oxo groups at positions 3, 7 and 11 (the 4alpha,5alpha stereoisomer). Isolated from Antrodia cinnamomea and Antrodia camphorata, it exhibits cytotoxic and anti-inflammatory activity.zhankuic acid A
adrenosteroneA 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17.adrenosterone
alphaxaloneRU 5135
cortisoneA C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20.cortisone
cucurbitacinsCucurbitacin S
nisonecortancyl
prednisoneA synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.prednisone

Research

Studies (55,857)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199031,271 (55.98)18.7374
1990's6,985 (12.51)18.2507
2000's7,354 (13.17)29.6817
2010's7,998 (14.32)24.3611
2020's2,249 (4.03)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials5,451 (8.81%)5.53%
Reviews3,608 (5.83%)6.00%
Case Studies13,788 (22.28%)4.05%
Observational179 (0.29%)0.25%
Other38,854 (62.79%)84.16%