A proteinogenic amino acid derivative resulting from reaction of L-methionine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-methionine by a heteroatom.
ChEBI ID: 84121
| Member | Definition | Role |
|---|---|---|
| methionine ethyl ester | An L-methionine derivative that is the ester obtained by formal condensation of the carboxy group of L-methionine with ethanol. | ethyl L-methioninate |
| methionine sulfone | An L-methionine derivative in which the sulfur has been oxidised to the corresponding sulfone. | L-methionine sulfone; methionine sulfone zwitterion |
| methionine sulfoximine | A methionine sulfoximine in which the amino group has S-stereochemistry. | L-methionine sulfoximine zwitterion; L-methionine sulfoximine |
| n-acetylmethionine | An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group. | N-acetyl-L-methionine |
| n-formylmethionine | A L-methionine derivative in which one of the hydrogens attached to the nitrogen is replaced by a formyl group. | N-formyl-L-methionine |
| trifluoromethionine | An L-alpha-amino acid, methionine, with the S-methyl group trifluoro-substituted. | trifluoro-L-methionine |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 489 (74.43) | 18.7374 |
| 1990's | 48 (7.31) | 18.2507 |
| 2000's | 57 (8.68) | 29.6817 |
| 2010's | 46 (7.00) | 24.3611 |
| 2020's | 17 (2.59) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 4 (0.59%) | 5.53% |
| Reviews | 21 (3.12%) | 6.00% |
| Case Studies | 2 (0.30%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 646 (95.99%) | 84.16% |