Nicotine Addiction

Synonym
Tobacco Dependence
Tobacco-Use Disorder
Nicotine Addiction
Nicotine Dependence
Nicotine Use Disorder

Excerpt	Reference
"Tobacco or nicotine dependence is now established as a disease and listed by several countries and by the World Health Organization."	( Fagerström, KO, 1991)
"Nicotine addiction is the most common serious medical problem in the country."	( Orleans, CT, 1995)
"Nicotine dependence is a complex phenomenon involving behavioral, biological, and pharmacological components that influence smoking cessation rates."	( Ahijevych, K; Gillespie, J, 1997)
"Nicotine addiction is more prevalent and more severe in people with a history of major depression, schizophrenia, or alcohol or other drug abuse problems."	( Benowitz, NL, 1999)
"Nicotine dependence is characterized by periods of relapse and remission."	( Dale, LC; Ebbert, JO; Hays, JT; Hurt, RD, 2000)
"Nicotine addiction is an extremely complex process that involves biological, psychological, behavioral, and cultural factors."	( Heishman, SJ, 1999)
"Nicotine addiction is a complex behavioral phenomenon comprising effects on several neural systems."	( Corrigall, WA; Picciotto, MR, 2002)
"Nicotine addiction is a chronic relapsing condition that can be difficult to treat."	( Jorenby, D, 2002)
"Nicotine addiction is a chronic disease characterized by frequent relapse."	( Aubin, HJ; Lagrue, G; Le Foll, B, 2002)
"Nicotine dependence is the major obstacle for smokers who want to quit."	( Cornuz, J; Gilbert, A; Paccaud, F; Pinget, C, 2003)
"The development of nicotine dependence is related to stimulation of the dopamine projections to the nucleus accumbens."	( Balfour, DJ, 2002)
"The consequences of tobacco dependence are both health related and economic."	( Fernandes, LC; Sellers, EM; Tyndale, RF, 2003)
"Tobacco dependence is prevalent among alcohol dependent patients, and causes increased morbidity and mortality."	( Joseph, AM; Nelson, DB; Nugent, SM; Willenbring, ML, 2003)
"Alcohol and nicotine dependence are commonly occurring disorders that together represent the most important preventable causes of morbidity and mortality in the United States."	( Johnson, BA, 2004)
"Tobacco dependence is recognised as a life-threatening disorder with serious oral health consequences which responds to treatment in the form of behavioural support and medication."	( Scully, C; Sutherland, G; Warnakulasuriya, S, 2005)
"Tobacco dependence is a chronic, relapsing disease causing an enormous burden of deaths."	( Gołecki, M; Jankowska, R; Kasibowska-Kuźniar, K; Porebska, I; Weryńska, B, 2004)
"Measures of tobacco dependence are mainly used in the clinical setting, but limited information is available on tobacco dependence on a population level."	( Apolone, G; Colombo, P; Gallus, S; Garattini, S; La Vecchia, C; Pacifici, R; Zuccaro, P, 2005)
"Nicotine addiction is one of the most prevalent addictive behaviors worldwide."	( Graul, AI; Prous, JR, 2005)
"Nicotine addiction is characterized by two distinct behaviors, chronic compulsive self-administration and the induction of a withdrawal syndrome upon cessation of nicotine consumption."	( Besson, M; Cazala, P; Changeux, JP; Cormier, A; David, V; Granon, S; Suarez, S, 2006)
"Nicotine dependence is the primary motivational factor perpetuating the tobacco smoking habit that is one of the leading preventable causes of morbidity throughout the world."	( Markou, A, 2007)
"Tobacco dependence is a chronic condition requiring repeat treatment and long-term follow-up."	( An, LC; Fu, SS; Joseph, AM; Nelson, DB; Nugent, S; Partin, MR; Snyder, A; Willenbring, ML, 2006)
"Nicotine dependence is probably mediated through the activation of multiple subtypes of neuronal nicotinic acetylcholine receptor (nAChR), among which the mesolimbic alpha(4)beta(2) subtype has a pivotal role."	( Chambers, LK; Coe, JW; Hurst, RS; Rollema, H; Stahl, SM; Williams, KE, 2007)
"Nicotine dependence is common in schizophrenia patients but rare in patients with obsessive-compulsive disorder."	( Fawzi, MH; Fawzi, MM; Khedr, HH, 2007)
"Tobacco dependence is an addiction characterised by compulsive drug-seeking and drug-taking behavior and intensive craving in the absence of tobacco."	( Bachmann, MF; Maurer, P, 2007)
"Tobacco dependence is a chronic disorder that is characterized by relapse after periods of abstinence."	( Bruijnzeel, AW; Desai, TV; Prado, M; Shah, HP; Zislis, G, 2007)
"Nicotine dependence is highly heritable and appears to be influenced by genes coding for some nicotine receptor subtypes, some neurotransmitter genes, and genes involved in neural connectivity."	( Benowitz, NL, 2008)
"Because tobacco dependence is characterized by relapses and remissions, clinicians should be ready to engage smokers and reengage relapsed smokers with options for new medication strategies and additional counseling resources."	( Burke, MV; Ebbert, JO; Hays, JT, 2008)
"Nicotine dependence is more prevalent than dependence on any other substance."	( Markou, A, 2008)
"Nicotine addiction is a complex, chronic condition with physiological and psychological/behavioural aspects that make smoking cessation extremely difficult."	( Reus, VI; Smith, BJ, 2008)
"We conclude that nicotine dependence is associated with attenuated opioid modulation of the HPA."	( al'Absi, M; Hatsukami, D; Westra, R; Wittmers, LE, 2008)
"Nicotine dependence is highly heritable."	( Benowitz, NL, 2009)
"The construct of tobacco dependence is important from both scientific and public health perspectives, but it is poorly understood."	( Baker, TB; Bolt, DM; Cannon, DS; Japuntich, SJ; Kim, SY; Niederdeppe, J; Piper, ME; Smith, SS, 2008)
"The core nature of nicotine dependence is evident in wide variations in how individuals become and remain smokers."	( Hiroi, N; Scott, D, 2009)
"Tobacco dependence is highly prevalent in depressed patients."	( Busto, UE; Houle, S; Kapur, S; Mayberg, H; Redden, L; Zawertailo, LA, 2009)
"Tobacco dependence is the most preventable cause of death and is a chronic, relapsing disorder in which compulsive tobacco use persists despite known negative health consequences."	( Bardo, MT; Crooks, PA; Dwoskin, LP; Smith, AM; Wooters, TE; Zhang, Z, 2009)
"Nicotine addiction is a complex behavioural alteration, in which many neuronal pathways and neurotransmitters are involved."	( Berrendero, F; Maldonado, R, 2010)
"Nicotine addiction is a chronic disorder characterized by a relatively high rate of relapse even after long period of abstinence."	( Biala, G; Budzynska, B; Staniak, N, 2010)
"Treating tobacco dependence is effective in patients with SMI."	( Banham, L; Gilbody, S, 2010)
"Tobacco dependence is a multidimensional phenomenon."	( Frost-Pineda, K; Hayden, AD; Liang, Q; Muhammad-Kah, RS; Sarkar, M, 2011)
"Tobacco dependence is a chronic disease that often requires repeated interventions and multiple attempts to quit."	( Aubin, HJ; Karila, L; Reynaud, M, 2011)
"Measured tobacco dependence is typically only modestly related to tobacco withdrawal severity among regular smokers making a quit attempt."	( Baker, TB; Bolt, D; Cook, JW; Loh, WY; Piper, ME; Schlam, TR; Smith, SS, 2012)
"Tobacco dependence is an addiction with high rates of relapse, resulting in multiple quit attempts in individuals who are trying to stop smoking."	( Blendy, JA; Hilario, MR; Turner, JR, 2012)
"Treating tobacco dependence is one of the most cost-effective actions in health care."	( Rigotti, NA, 2012)
"Nicotine addiction is a major public health problem, resulting in primary glutamatergic dysfunction."	( Akkus, F; Ametamey, SM; Buck, A; Burger, C; Gomez Mancilla, B; Hasler, G; Johayem, A; Sovago, J; Treyer, V; Umbricht, D, 2013)
"Nicotine addiction is characterized by symptoms such as: "hunger" smoking, difficulty in controlling behavior on smoking or the number of cigarettes smoked, nicotine withdrawal, the occurrence of tolerance, neglect of interests, as well as devoting more time on activities related to smoking, follow-up smoking despite knowledge of its dangers."	( Milnerowicz, H; Sliwińska-Mossoń, M; Zieleń, I, 2012)
"Alcohol and nicotine dependence are common in schizophrenia."	( Abdul-Malak, Y; Ajagbe, TO; Batki, SL; Dimmock, JA; Meszaros, ZS; Wang, D, 2013)
"Tobacco dependence is highly prevalent among drug-dependent patients."	( Coscas, S; Karila, L; Lowenstein, W; Petit, A; Reynaud, M; Zarmdini, R, 2013)
"Nicotine addiction is a serious health problem resulting in millions of preventable deaths worldwide."	( Kanit, L; Keser, A; Nesil, T; Pogun, S, 2013)
"Tobacco dependence is a chronic condition characterized by susceptibility of relapse over years."	( Aruna, DS; Mohanty, VR; Rajesh, GR, 2013)
"Tobacco dependence is associated with the emergence of negative emotional states during withdrawal, including anxiety and nociceptive hypersensitivity."	( Cohen, A; Edwards, S; George, O; Koob, GF; Leão, RM; Schulteis, G; Treweek, J, 2015)
"Nicotine dependence is the leading cause of death in the United States."	( Berg, SA; Chambers, RA; Cooley, BS; Engleman, EA; Sentir, AM, 2014)
"Nicotine addiction is associated with the presence of drug-context and drug-cue associations that trigger drug seeking behavior and altered cognition during periods of abstinence, which contributes to relapse."	( Gould, TJ; Leach, PT, 2014)
"Treatment for tobacco dependence is not available in many low-resource settings, especially in developing countries."	( Dow, WH; Rungruanghiranya, S; White, JS, 2013)
"Vaccination against nicotine addiction is a new approach, still in study (ongoing phase III clinical trial) as new treatment of tobacco addiction."	( Fernández, PL, 2012)
"Nicotine dependence is a major cause of mortality and morbidity all over the world."	( Gupta, T; Jain, R; Majumder, P, 2013)
"Nicotine addiction is associated with the development of tolerance and the emergence of withdrawal symptoms upon cessation of chronic nicotine administration."	( Adoff, MD; Blendy, JA; Gould, TJ; Wilkinson, DS; Yildirim, E, 2014)
"Nicotine dependence is a widely prevalent and harmful chronic addictive disorder."	( D'Souza, G; Mony, PK; Rose, DP; Sreedaran, P; Srinivasan, K, 2014)
"Tobacco dependence is similar to heroin addiction in its mechanisms and level of addictiveness or treatment success."	( Kmeťová, A; Králíková, E; Zvolská, K, 2014)
"Nicotine addiction is most likely a result of a combination of factors including the rewarding effects of the drug; these effects, however, might be influenced by genetic background."	( Gould, TJ; Kutlu, MG; Ortega, LA, 2015)
"Smoking, especially nicotine dependence is associated with more severe symptoms of depression and anxiety disorders."	( Jamal, M; Penninx, BW; Van der Does, W, 2015)
"Nicotine addiction is a major public health problem and is associated with primary glutamatergic dysfunction."	( Akkus, F; Ametamey, SM; Buck, A; Hasler, G; Johayem, A; Mancilla, BG; Sovago, J; Treyer, V, 2016)
"Nicotine addiction is considered to be the main preventable cause of death worldwide."	( Bailey, A; Georgiou, P; Kitchen, I; Metaxas, A; Winsky-Sommerer, R; Zanos, P, 2015)
"Nicotine addiction is highly prevalent in current society and is often comorbid with other diseases."	( de Kloet, SF; De Vries, TJ; Mansvelder, HD, 2015)
"The high nicotine dependence is one of the contributing factors to failure of attempts to quit."	( Ben Salah, A; Ben Salem, K; Bouanene, I; Elmhamdi, S; Harizi, C; Soltani, ME; Sriha Belguith, A, 2015)
"Tobacco dependence is associated with increased risk of disease and premature death."	( Baurley, JW; Bergen, AW; Conti, DV; Edlund, CK; Pardamean, CI, 2016)
"Nicotine dependence is characterized as a neural circuit dysfunction, particularly with regard to the reward circuit."	( Huang, P; Qian, W; Shen, Z; Wang, C; Yang, Y; Yu, H; Zhang, M, 2016)
"Nicotine dependence is maintained by neurobiological adaptations in the dopaminergic brain reward pathway with the contribution of opioidergic circuits."	( Carboni, L; Romoli, B; Romualdi, P; Zoli, M, 2016)
"Nicotine addiction is a worldwide epidemic that claims millions of lives each year."	( Bergamini, MA; Chwalek, M; George, O; Grieder, TE; Maal-Bared, G; van der Kooy, D; Vargas-Perez, H; Yee, M, 2017)
"Nicotine use disorder is highly prevalent among methadone maintenance patients with its tobacco-related problems."	( Hoong, MC; Joyce, YC; Loh, HS; Yee, A, 2018)
"Our results suggest nicotine dependence is associated with a hypersensitivity to cigarette rewards but not a hyposensitivity to nondrug rewards."	( Aston, ER; Bloomfield, MAP; Curran, HV; Das, RK; East, K; Freeman, TP; Gaule, A; Lawn, W; Morgan, CJA, 2018)
"Alcohol and nicotine addiction are frequently co-morbid."	( Lee, AM; Maertens, JJ; Mason, MM; O'Rourke, KY; Touchette, JC, 2018)
"The prevalence of nicotine dependence is higher than that for any other substance abuse disorder; still, the underlying mechanisms are not fully established."	( Adermark, L; Lagström, O; Licheri, V; Lotfi, A; Mathur, B; Patton, MH; Wigström, H, 2018)
"Nicotine addiction is the proximate cause of disease and death from cigarette smoking."	( Benowitz, NL; Henningfield, JE, 2018)
"Nicotine addiction is known to modulate neurotransmission and alter the brain structure."	( Aigner, CS; Bagga, D; Cecchetto, C; Fischmeister, FPS; Schöpf, V, 2018)
"Nicotine dependence is likely to mediate the relation between delay discounting and the choice to smoke."	( Lunden, S; Malhotra, R; O'Connor, RJ; Prashad, N; Sheffer, CE, 2019)
"Tobacco dependence is a leading cause of preventable disease and death worldwide."	( Fowler, CD; Imad Damaj, M; Turner, JR, 2020)
"As alcohol and nicotine use disorders are entwined, it may be possible to develop a single medication to treat both."	( Bardo, MT; Chandler, CM; Maggio, SE; Nixon, K; Peng, H, 2020)
"While nicotine addiction is a truly global problem, the use of areca nut (betel) products is also a serious addiction associated with public health issues across most of South Asia, impacting as many as 600 million people."	( Brunzell, DH; De Biasi, M; Papke, RL, 2020)
"Nicotine dependence is partially accountable for increased risks of lung cancer (OR = 1."	( Boyd, K; Brown, MC; Carroll, JC; Chen, Z; Eng, L; Giuliani, ME; Goldstein, DP; Hung, RJ; Khodayari Moez, E; Liu, G; Mirshams, M; Patel, D; Pierre, A; Thomas, S; Xu, W, 2020)
"Nicotine dependence is one of the main reasons for the continuation of smoking among adolescents."	( Barbouni, A; Basagiannis, A; Hadjichristodoulou, C; Mouchtouri, V; Rachiotis, G; Soteriades, ES; Soteriades, S, 2020)
"Nicotine addiction is a leading avoidable brain disorder globally."	( Huang, Y; Johnson, B; Li, JX; Liu, J; Wu, R; Zhang, Y, 2022)
"Nicotine addiction is a chronic relapsing brain disorder, and cigarette smoking is the leading cause of preventable death in the United States."	( Beloate, LN; Doolittle, J; Froeliger, B; Garcia-Keller, C; Kalivas, PW; Meyerink, ME; Nall, RW; Penaloza, T, 2022)
"Persons with nicotine addiction are reluctant to attempt to stop using nicotine products-despite recognizing it to be a problem-because they are feeling discouraged by multiple past unsuccessful attempts at quitting."	( DiClemente, CC; Kolodner, G; Miller, MM, 2022)
"Nicotine addiction is a public health problem."	( Bigorre, N; Brunet, J; Cesari, B; Gomez, M; Jeudy, J; Petit, A; Rabarin, F; Raimbeau, G; Saint-Cast, Y, 2023)
"Nicotine addiction is a neuropsychiatric disorder with dysfunction in cortices as well as white matter (WM)."	( Chen, Y; Fan, C; Gou, H; Hong, W; Liu, Y; Lv, W; Pan, Y; Ren, J; Song, H; Wang, Y; Wei, Z; Zha, R; Zhang, P; Zhang, X; Zhou, Y, 2023)

Excerpt	Reference
"Nicotine dependence has a biological substratum defined as "neuroadaptation to nicotine."	( Ochoa, EL, 1994)
"The discovery that nicotine dependence has a major genetic component has stimulated much interest and many research studies."	( Lillington, GA; Sarinas, PS; Vaszar, LT, 2002)
"Nicotine addiction has been identified as the primary contributor to continued widespread tobacco use worldwide."	( Hatsukami, DK; Kotlyar, M, 2002)
"Nicotine dependence has become more frequently associated with psychiatric illness in recent decades, and patients who have schizophrenia are at highest risk and have the poorest prognosis for stopping their addiction."	( Boules, M; Fredrickson, P; Lin, SC; Richelson, E, 2005)
"Nicotine dependence has been associated with impulsivity and discounting delayed/uncertain outcomes."	( Kitamura, N; Ohmura, Y; Takahashi, T, 2005)
"Nicotine dependence has been linked to attention-deficit hyperactivity disorder (ADHD) symptoms in both clinical and general populations."	( Jepson, C; Lerman, C; Lynch, K; Patterson, F; Ray, R; Rukstalis, M; Strasser, A, 2009)
"ECIG-induced nicotine dependence has become an important concern, as some ECIGs deliver very little nicotine while some may exceed the nicotine delivery profile of a tobacco cigarette."	( Cobb, CO; Eissenberg, T; Hendricks, PS, 2015)
"Tobacco dependence has been defined as a chronic relapsing disease."	( Awan, S; Haque, AS; Irfan, M; Khan, JA; Samani, ZA; Shahzad, H, 2016)
"Animal models of nicotine addiction have helped identify a variety of interacting neural systems involved in the pathophysiology of tobacco addiction."	( DiPalma, D; Evans, J; Hall, BJ; Howard, S; Levin, ED; McMillan, C; Nangia, A; Rezvani, AH; Slade, S; Tharwani, S; Wells, C; Willette, BKA, 2019)
"Addressing nicotine addiction has been given a low priority, compared with other substance use disorders (SUDs), by the addiction treatment field."	( DiClemente, CC; Kolodner, G; Miller, MM, 2022)

Excerpt	Reference
"Nicotine dependence affects smoking topography."	( Antosiewicz, B; Czogała, J; Goniewicz, MŁ; Koszowski, B; Sobczak, A; Szołtysek-Bołdys, I; Zielińska-Danch, W; Łabanowicz, A, 2010)

Excerpt	Reference
"Greater knowledge of the effects of nicotine addiction and employment in programs that provided nicotine addiction education or treatment increased the odds of counselors' providing nicotine counseling."	( Bobo, JK; Hoffman, AL; Slade, J, 1995)
"Tools such as the Fagerstrom Test for Nicotine Dependence can help the physician learn about the patient's smoking habit and develop an effective treatment plan."	( Danis, PG; Seaton, TL, 1997)
"The search for effective treatments for nicotine dependence has generated a wide variety of non-nicotine approaches based on the neuropharmacologic and sensory basis for tobacco use."	( Ferry, LH, 1999)
"This intensive nicotine dependence treatment in seriously dependent patients, proved to be successful, regardless of the previous psychiatric history."	( Ferrer, V; Ramos, AM; Santander, JA; Seijas, D, 1999)
"(2) Effective treatments for tobacco dependence exist and all tobacco users should be offered those treatments."	( , 2000)
"We describe the degree of nicotine addiction and readiness to quit smoking among people with a history of injection drug use, comparing those in a methadone maintenance treatment program (MMTP) with active illicit drug injectors in a needle exchange program (NEP)."	( Clarke, JG; Gogineni, A; McGarry, KA; Stein, MD, 2001)
"If effective for treating tobacco dependence in humans, vaccination will likely benefit from concurrent use of counseling (as is the case with other medications for smoking cessation) and perhaps from its combination with other medications that act via different mechanisms."	( Malin, D; Pentel, P, 2002)
"The efficacy of bupropion for the treatment of tobacco dependence is attributed to the blockage of dopamine reuptake in the mesolimbic dopaminergic system."	( Ebbert, JO; Hays, JT, 2003)
"The CE of first-line treatments for nicotine dependence varied widely with age and sex and was sensitive to the assumption for the natural quit rate."	( Cornuz, J; Gilbert, A; Paccaud, F; Pinget, C, 2003)
"We investigated whether severity of nicotine dependence was related to treatment outcome for cocaine-dependent individuals."	( Leone, FT; Murray, HW; Patkar, AA; Thornton, CC; Vergare, MJ; Weinstein, SP, 2003)
"This article reviews the biology of nicotine addiction and the most effective treatments for nicotine dependence."	( Glover, ED; Glover, PN; Payne, TJ, 2003)
"In study 1, we administered the Nicotine Dependence Syndrome Scale (NDSS) to 317 smokers in a smoking cessation study."	( Hickcox, M; Shiffman, S; Waters, A, 2004)
"Understanding nicotine dependence, its causes, consequences, and effective treatments is critical to the nation's public health agenda."	( McClure, JB; Swan, GE; Zbikowski, SM, 2004)
"Intensive treatment for nicotine dependence, environmental interventions, and innovative harm reduction strategies are recommended to address the barriers to quitting observed in this population of pregnant women."	( Diclemente, C; Haug, NA; Svikis, DS, 2004)
"High levels of nicotine dependence did not affect time to lapse but were associated with slower recovery from lapse across treatment and follow-up phases."	( Audrain-McGovern, J; Brown, RA; Epstein, LH; Hawk, LW; Lerman, C; Niaura, R; Patterson, F; Wileyto, EP, 2005)
"790 smokers treated at the Tobacco Dependence Clinic in New Jersey from 2001-2003 and contacted 4 weeks after quit-date were studied."	( Burke, MV; Foulds, J; Richardson, DL; Shah, P; Steinberg, MB, 2006)
"In multivariate analyses, lower nicotine dependence, prior use of smoking cessation pharmacotherapy, and lower methadone dose were associated with being in the preparation stage."	( Arnsten, J; Li, X; Modali, L; Nahvi, S; Richter, K, 2006)
"Evidence on how to tailor nicotine dependence treatment to specific race/ethnic groups is limited."	( Botello-Harbaum, M; Covey, LS; Fried, J; Glassman, AH; LoDuca, C; Masmela, J; Salzman, V, 2008)
"In addition, new indications for treating tobacco dependence and withdrawal show promise for reducing tobacco use and associated disease."	( Buchhalter, AR; Fant, RV; Henningfield, JE, 2008)
"Pharmacotherapy can provide effective treatment of tobacco dependence and withdrawal, and thereby facilitate efforts to achieve and sustain tobacco abstinence."	( Buchhalter, AR; Buchman, AC; Fant, RV; Henningfield, JE, 2009)
"Understanding the mechanisms underlying nicotine addiction to develop more effective treatment is a public health priority."	( Buchholz, B; Gu, H; Hong, LE; Ross, TJ; Salmeron, BJ; Stein, EA; Thaker, GK; Yang, Y, 2009)
"Correlation of nicotine addiction severity and cingulate resting-state functional connectivity, and effects of short-term nicotine administration on connectivity strength."	( Buchholz, B; Gu, H; Hong, LE; Ross, TJ; Salmeron, BJ; Stein, EA; Thaker, GK; Yang, Y, 2009)
"The severity of nicotine addiction was associated with the strength of dorsal anterior cingulate cortex (dACC)-striatal circuits, which were not modified by nicotine patch administration."	( Buchholz, B; Gu, H; Hong, LE; Ross, TJ; Salmeron, BJ; Stein, EA; Thaker, GK; Yang, Y, 2009)
"There are clear benefits from treating tobacco dependence on the rate of clinical outcomes."	( Frishman, WH, 2009)
"Even if the efficacy of treatment of tobacco dependence is proven, it is not the most cost-effective method of Tobacco Control and its efficiency is still questionable."	( Dubois, G, 2009)
"We assessed the effects of treatment for tobacco dependence on the health-related QoL in a 52-week randomized controlled trial of varenicline and bupropion sustained release (SR)."	( Baker, CL; Bushmakin, AG; Cappelleri, JC; Croghan, IT; Hays, JT, 2012)
"Varenicline may be a useful aid for treating tobacco dependence among smokers who are in stable recovery from alcohol dependence."	( Croghan, IT; Ebbert, JO; Hays, JT; Hurt, RD; Schroeder, DR, 2011)
"The Fagerström Test for Nicotine Dependence (FTND) is a widely administered six-item questionnaire used as a measure of nicotine dependence."	( Frost-Pineda, K; Hayden, AD; Liang, Q; Muhammad-Kah, RS; Sarkar, M, 2011)
"There is scant information on nicotine dependence in smokers not seeking cessation treatment."	( Agudo, A; Ariza, C; Fernández, E; Fu, M; Martínez-Sánchez, JM; Moncada, A; Pascual, JA, 2012)
"In this study, two proposed scales of nicotine dependence were compared: self-administered nicotine intake and acute heart rate sensitivity to smoking."	( Kane, CJ; Loprinzi, PD; Walker, JF, 2013)
"However, the current animal models of nicotine dependence have focused on the mechanisms that mediate the acute reinforcing effects of nicotine and failed to link increased anxiety and pain during abstinence with excessive nicotine self-administration."	( Cohen, A; Edwards, S; George, O; Koob, GF; Leão, RM; Schulteis, G; Treweek, J, 2015)
"This trial evaluated varenicline for treating smokeless tobacco dependence in India."	( Goelz, P; Gupta, T; Jain, R; Jain, V; Jhanjee, S; Mittal, S; Schnoll, RA; Wileyto, EP, 2014)
"Varenicline is safe for treating smokeless tobacco dependence in India, and further examination of this medication for this important public health problem is warranted."	( Goelz, P; Gupta, T; Jain, R; Jain, V; Jhanjee, S; Mittal, S; Schnoll, RA; Wileyto, EP, 2014)
"Despite progress made in the treatment of tobacco dependence, currently available treatments are effective for only a fraction of smokers."	( Bandrés, F; de Lucas Ramos, P; Gómez-Gallego, F; López Martín, S; Lucia, A; Rodríguez González-Moro, JM; Santiago, C; Verde, Z, 2014)
"Given that development of nicotine addiction largely depends on the effects of nicotine on the mesolimbic dopamine system these findings indicate that the GLP-1 receptor may be a potential target for the development of novel treatment strategies for nicotine cessations in humans."	( Egecioglu, E; Engel, JA; Jerlhag, E, 2013)
"Vaccination against nicotine addiction is a new approach, still in study (ongoing phase III clinical trial) as new treatment of tobacco addiction."	( Fernández, PL, 2012)
"A newer venture to nicotine dependence treatment is a nicotine vaccine which is yet to get footsteps in common practice."	( Gupta, T; Jain, R; Majumder, P, 2013)
"Thirty subjects with nicotine dependence participated in 4 weeks of treatment with either virtual CET (n=15) or CBT (n=15)."	( Choi, JS; Gwak, AR; Hwang, JY; Jung, HY; Kwon, JS; Lee, JY; Park, CB; Park, SM; Seol, JM, 2014)
"They are not used to treat nicotine addiction or other disease, but to enable continued use of nicotine."	( Farsalinos, KE; Stimson, GV, 2014)
"Understanding the underlying causes of nicotine addiction will require a multidisciplinary approach examining the key molecular, cellular and neuronal circuit functional changes that drive escalating levels of nicotine self-administration."	( Nashmi, R; Renda, A, 2014)
"In particular, primate studies on nicotine addiction and evaluation of therapies to prevent or overcome nicotine addiction are likely to be highly predictive of treatment outcomes in humans."	( Allen, DC; Ford, MM; Grant, KA; Kuryatov, A; Lindstrom, J; Shorey-Kendrick, LE; Spindel, ER; Wilhelm, L, 2015)
"Pharmacological treatments for tobacco dependence, such as nicotine replacement therapy (NRT), have been shown to be safe and effective interventions for smoking cessation."	( Aveyard, P; Farley, A; Hollands, GJ; Lindson-Hawley, N; McDermott, MS; Vogt, F, 2015)
"Delayed antibiotics treatment and nicotine addiction are the main risk factors associated with abscess formation of leg erysipelas in these countries."	( Akakpo, S; Boukari, T; Cissé, M; Diané, BF; Diatta, AB; Dicko, A; Dieng, MT; Diop, A; Faye, O; Kobengue, L; Kouassi, I; Kourouma, SH; Landoh, DE; Ly, F; Mandengue, C; Niamba, P; Pitché, PV; Saka, B; Sangaré, A; Soumah, MM; Tchangaï-Walla, K, 2015)
"In Japan a treatment of nicotine addiction with varenicline or nicotine patch has been started under health insurance coverage since 2006."	( Uruma, R, 2016)
"142 adults with nicotine dependence (ND) and PTSD were randomized to a treatment program consisting of varenicline, smoking cessation counseling, and PE (VARCC + PE) or to VARCC only."	( Asnaani, A; Foa, EB; Gariti, P; Imms, P; Rosenfield, D; Zandberg, LJ, 2017)
"We examined self-reported nicotine dependence and associated factors in a large sample of opioid-dependent patients receiving methadone maintenance treatment (MMT) in northern Vietnam."	( Do, HP; Dunne, MP; Latkin, CA; Le, GT; Le, HT; Ngo, C; Nguyen, CT; Nguyen, LH; Nguyen, LK; Phan, HTT; Thi Nguyen, HL; Thi Nguyen, NP; Tran, BX; Tran, TD; Vu, TMT, 2017)
"However, the treatment modalities for nicotine use disorder remain limited."	( Hoong, MC; Joyce, YC; Loh, HS; Yee, A, 2018)
"Baseline measures of nicotine dependence, AD severity, psychopathology, motivation to quit smoking, and smoking-related cognitions were used to predict smoking quantity (cigarettes per day) at post-treatment and follow-up."	( Anthenelli, RM; Daniel, BE; Heffner, JL; Isgro, M; Lee, SY; Worley, MJ, 2018)
"Treatment providers can use severity of nicotine dependence and AD, motivation to quit, smoking-related cognitions, and severity of depression to guide treatment and improve outcomes among AD smokers."	( Anthenelli, RM; Daniel, BE; Heffner, JL; Isgro, M; Lee, SY; Worley, MJ, 2018)
"Among cancer patients treated for tobacco dependence with varenicline, adherence is associated with smoking cessation."	( Bastian, J; Carroll, A; Crawford, G; Flitter, A; Hitsman, B; Jao, NC; Kalhan, R; Leone, F; Schnoll, R; Weisbrot, J, 2019)
"The benefits of varenicline for treating tobacco dependence among cancer patients may depend upon boosting adherence by addressing early signs of depression and reducing the reinforcing dimensions of cigarettes."	( Bastian, J; Carroll, A; Crawford, G; Flitter, A; Hitsman, B; Jao, NC; Kalhan, R; Leone, F; Schnoll, R; Weisbrot, J, 2019)
"Among those with lower baseline nicotine dependence scores, cigarette smoking was reduced in the active treatment group compared to placebo."	( Babalonis, S; Baker, NL; Ghitza, UE; Gray, KM; McClure, EA; Montgomery, L; Sonne, SC; Terry, GE; Tomko, RL, 2018)
"Patients with chronic PTSD and nicotine dependence (N = 142) received up to 12 sessions of smoking cessation counseling combined with varenicline or integrated prolonged exposure therapy and cessation counseling combined with varenicline."	( Asnaani, A; Fitzgerald, HE; Foa, EB; Jerud, A; Kaczkurkin, AN, 2020)
"Pharmacological treatments for tobacco dependence, such as nicotine replacement therapy (NRT), have been shown to be safe and effective interventions for smoking cessation."	( Aveyard, P; Farley, A; Hollands, GJ; Lindson, N; Naughton, F, 2019)
"Varied facets of nicotine dependence predicted adherence across treatment conditions 4 weeks post-quit and between 4- and 16-weeks post-quit in A-OT, with greater baseline dependence and greater smoking trigger exposure and reactivity predicting greater medication use."	( Baker, TB; Cook, JW; Kim, N; Loh, WY; McCarthy, DE; Piper, ME; Schlam, TR, 2019)
"All smokers underwent intensive treatment for tobacco dependence; 33 smokers were still abstinent at the 12-month follow-up."	( Hubacek, JA; Kralikova, E; Kurcova, I; Lanska, V; Maresova, V; Pankova, A; Stepankova, L; Zvolska, K, 2021)
"As alcohol and nicotine use disorders are entwined, it may be possible to develop a single medication to treat both."	( Bardo, MT; Chandler, CM; Maggio, SE; Nixon, K; Peng, H, 2020)
"Smokers received intensive treatment of tobacco dependence with pharmacotherapy options."	( Adamcekova, Z; Kralikova, E; Kuhn, M; Noland, D; Pankova, A; Stepankova, L; Zvolska, K, 2021)
"Quercetin reduced the risk of nicotine dependence and has a potential effect to use as a therapy for nicotine dependence, especially as a preventive agent."	( Ardianto, C; Lailis, SR; Rahmadi, M; Ratri, DMN; Suasana, D, 2021)
"To find satisfactory treatment for nicotine addiction, synaptic and cellular mechanisms should be investigated comprehensively."	( Koga, K; Toyoda, H, 2021)
"Treatment of nicotine dependence in the medical management of opioid dependence seems promising, but at what point in the course - simultaneously, shortly after, or far behind - has yet to be determined."	( Larsson, M, 2022)
"Addressing nicotine addiction has been given a low priority, compared with other substance use disorders (SUDs), by the addiction treatment field."	( DiClemente, CC; Kolodner, G; Miller, MM, 2022)
"By examining the interactions between nicotine addiction and overweight from neuroimaging and molecular perspectives, this study provides some ideas for the treatment of both co-morbidities."	( Chen, J; Cheng, J; Gao, X; Han, S; Niu, X; Wang, W; Wei, Y; Yang, Z; Zhang, M; Zhang, Y; Zhou, B, 2023)
"By examining the interactions between nicotine addiction and overweight from neuroimaging and molecular perspectives, this study provides some ideas for the treatment of both co-morbidities."	( Chen, J; Cheng, J; Gao, X; Han, S; Niu, X; Wang, W; Wei, Y; Yang, Z; Zhang, M; Zhang, Y; Zhou, B, 2023)
"Brief, valid assessment of nicotine dependence among adults who use ENDS is needed to guide treatment for nicotine dependence in this group."	( Bensch, L; Carl, E; Foulds, J; Goniewicz, ML; Hyland, A; Liskiewicz, A; Mahoney, MC; McDonough, B; Sheffer, CE; Shevorykin, A; Szeliga, A; Vantucci, D, 2023)
"Fagerström test for nicotine dependence scores were measured at baseline and biochemically verified smoking cessation was assessed at end of treatment."	( Chenoweth, MJ; Knight, J; Lerman, C; Tyndale, RF, 2023)
"Although nicotine dependence severity neither mediated nor moderated CYP2A6 associations with smoking cessation, incorporating information on dependence may optimize the choice of smoking cessation treatment aid in CYP2A6 normal and slow metabolizers."	( Chenoweth, MJ; Knight, J; Lerman, C; Tyndale, RF, 2023)
"Findings revealed that recovery from nicotine addiction was characterized by higher response thresholds when making value-based decisions about tobacco-related cues; this may serve as a novel target for treatment interventions that focus on helping people to stop smoking."	( Copeland, A; Field, M; Stafford, T, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	227 (5.61)	23.3326
1990's	238 (5.89)	12.5806
2000's	1427 (35.30)	18.1394
2010's	1743 (43.11)	28.8240
2020's	408 (10.09)	9.53

Drug	Relationship Strength	Studies	Trials
2,3-diphosphoglycerate	low	1	0
gamma-aminobutyric acid	medium	22	3
acetaldehyde	low	5	0
acetone	low	1	0
agmatine	low	1	0
ammonium hydroxide	low	4	0
benzene	medium	2	1
butyric acid	low	1	0
carbamates	low	2	0
carbon monoxide	medium	195	82
methane	low	1	0
choline	low	3	0
coumarin	low	1	0
salicylic acid	medium	1	1
nornicotine	medium	7	1
nicotine imine	low	2	0
bupropion	medium	410	116
bw 306u	low	1	0
3,4-dihydroxyphenylacetic acid	low	2	0
creatine	low	1	0
lactic acid	low	1	0
formaldehyde	low	1	0
glycine	medium	3	1
glycerol	low	2	0
histamine	low	1	0
dihydroxyphenylalanine	low	2	0
kynurenine	low	1	0
methanol	low	1	0
inositol	low	1	0
melatonin	low	1	0
nickel	medium	2	1
nitrates	low	1	0
nitroxyl	medium	1	1
nitrites	low	2	0
nitrous oxide	low	2	0
propylene glycol	low	1	0
pyrazinamide	low	1	0
pyridine	low	1	0
pyruvic acid	low	1	0
succinic acid	medium	1	1
sulfur dioxide	low	1	0
taurine	medium	4	1
thiamine	low	1	0
toluene	medium	1	1
uric acid	medium	3	1
urea	medium	4	1
sk&f 81297	low	1	0
ibotenic acid	low	1	0
menthol	medium	72	10
1-anilino-8-naphthalenesulfonate	low	1	0
2-hydroxysaclofen	low	1	0
3,4-methylenedioxyamphetamine	low	1	0
n-methyl-3,4-methylenedioxyamphetamine	medium	6	1
3-methylcholanthrene	low	1	0
homovanillic acid	low	2	0
phenytoin	low	1	0
hydroxyindoleacetic acid	low	6	0
albendazole	medium	1	1
am 251	low	5	0
theophylline	medium	2	1
arecoline	low	3	0
aspirin	low	1	0
baclofen	medium	7	1
benzo(a)pyrene	low	2	0
bupivacaine	medium	1	1
buspirone	medium	1	1
caffeine	medium	21	1
carbamazepine	low	1	0
carvedilol	medium	1	1
chelerythrine	low	1	0
chlordiazepoxide	low	1	0
chloroquine	medium	1	1
chlorpromazine	low	2	0
eucalyptol	low	1	0
citalopram	low	3	0
clofibrate	low	1	0
clonidine	medium	26	3
desipramine	low	1	0
amphetamine	medium	8	1
diazepam	medium	3	1
dipyridamole	low	1	0
disulfiram	low	5	0
donepezil	low	1	0
doxazosin	medium	1	1
doxepin	low	2	0
ebastine	low	1	0
fenfluramine	low	2	0
fenofibrate	medium	2	1
fentanyl	low	2	0
fluphenazine	medium	2	1
flumazenil	low	1	0
fluoxetine	medium	3	1
fluphenazine depot	low	1	0
flurazepam	low	1	0
gabapentin	medium	2	1
glyburide	low	1	0
glyphosate	low	1	0
guaifenesin	low	1	0
guanfacine	low	1	0
guvacine	low	1	0
haloperidol	medium	4	1
ici 204448	low	2	0
imipramine	low	5	0
isoniazid	low	1	0
ketamine	low	3	0
ketanserin	low	1	0
kynurenic acid	low	1	0
mecamylamine	medium	74	6
memantine	medium	3	2
mescaline	low	1	0
metformin	medium	2	1
methadone	medium	41	12
methoxsalen	low	2	0
methylphenidate	medium	10	5
metyrapone	low	1	0
midazolam	low	1	0
modafinil	medium	4	1
muscimol	low	2	0
apnea	low	1	0
neostigmine	medium	1	1
nimodipine	low	2	0
nitrazepam	low	1	0
nitroglycerin	low	2	0
nortriptyline	medium	27	4
ofloxacin	medium	1	1
oxazepam	low	1	0
oxidopamine	low	1	0
oxybutynin	medium	11	6
4-(2'-methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine	low	1	0
palmidrol	low	1	0
phenacetin	low	1	0
phenobarbital	low	1	0
prazosin	low	3	0
propranolol	medium	8	2
pyrilamine	low	1	0
pyrimethamine	medium	1	1
risperidone	low	2	0
saccharin	low	1	0
sibutramine	medium	1	1
sodium fluoride	medium	2	1
temozolomide	medium	1	1
tolmetin	low	1	0
vigabatrin	low	2	0
pirinixic acid	low	1	0
zomepirac	low	1	0
corticosterone	low	7	0
lysergic acid diethylamide	low	1	0
thyroxine	low	1	0
dextroamphetamine	medium	5	2
prednisone	low	1	0
dehydroepiandrosterone	medium	2	1
serine	low	1	0
aspartic acid	low	1	0
glutamine	medium	3	1
lysine	low	1	0
physostigmine	low	1	0
sucrose	low	8	0
ethinyl estradiol	low	1	0
apomorphine	low	3	0
adenosine diphosphate	low	1	0
bromodeoxyuridine	low	1	0
carbostyril	medium	2	1
levodopa	medium	2	1
tyrosine	medium	4	2
leucine	low	1	0
methacholine chloride	low	1	0
methionine	low	9	0
phenylalanine	medium	1	1
desoxycorticosterone	low	1	0
cycloserine	medium	2	2
chlorisondamine	low	1	0
ampicillin	low	1	0
valine	low	9	0
tryptophan	medium	4	2
arginine	low	2	0
vinyl chloride	low	2	0
ethylene oxide	low	2	0
phencyclidine	medium	7	1
isoprene	low	1	0
acrylic acid	medium	1	1
rhodamine b	medium	1	1
n-vinyl-2-pyrrolidinone	medium	1	1
quinoxalines	medium	197	43
trehalose	low	2	0
ethylbenzene	medium	1	1
quinuclidines	low	1	0
acrylonitrile	medium	1	1
cyclohexanol	medium	4	2
pyrroles	medium	2	1
thiophenes	low	2	0
framycetin	medium	1	1
pregnenolone	low	1	0
yohimbine	low	4	0
quinazolines	low	1	0
indazoles	medium	1	1
benzoxazoles	low	4	0
isoxazoles	low	1	0
oxazoles	low	3	0
thiazoles	medium	2	1
pyrazines	low	1	0
hydrazine	medium	1	1
thiocyanate	medium	9	3
galantamine	medium	5	3
aminoimidazole carboxamide	low	1	0
kynuramine	low	1	0
hydantoins	medium	1	1
cytisine	medium	20	4
salsolidine	low	1	0
arecaidine	low	1	0
alpha-aminopyridine	low	1	0
mustard gas	low	1	0
methadyl acetate	low	1	0
psilocybin	medium	5	2
methoxyhydroxyphenylglycol	medium	3	1
methamphetamine	medium	18	2
malondialdehyde	medium	4	1
bis(chloromethyl) ether	low	1	0
anatabine	medium	2	1
levulinic acid	low	1	0
alpha-naphthoflavone	low	1	0
acetylcysteine	medium	16	11
dehydroepiandrosterone sulfate	low	1	0
levonorgestrel	medium	1	1
ethambutol	low	1	0
phenazocine	low	1	0
calcium peroxide	medium	1	1
durapatite	low	1	0
manganese dioxide	medium	1	1
zinc oxide	medium	1	1
d-alpha tocopherol	low	3	0
s,n,n'-tripropylthiocarbamate	medium	261	25
dronabinol	medium	6	1
flupenthixol	low	3	0
sabinene	low	1	0
tranylcypromine	low	1	0
1-hydroxypyrene	medium	2	1
n-methylaspartate	low	1	0
manganese	medium	1	1
mercury	medium	1	1
molybdenum	medium	1	1
silver	medium	1	1
titanium	medium	1	1
cadmium	low	5	0
gold	medium	1	1
galactosamine	medium	1	1
zinc sulfate	medium	1	1
tricalcium phosphate	medium	1	1
deuterium	low	1	0
ozone	low	1	0
radon	low	2	0
trolamine salicylate	low	5	0
titanium dioxide	medium	1	1
selegiline	medium	5	5
n'-nitrosonornicotine	medium	2	2
fluorides	low	1	0
lisuride	medium	1	1
bromocriptine	medium	2	1
phenyl acetate	low	1	0
cetylpyridinium chloride anhydrous	medium	18	2
pregnanolone	low	1	0
4-methoxyamphetamine	low	4	0
dihydro-beta-erythroidine	low	5	0
glutamic acid	medium	28	2
torpedo	low	1	0
substance p	low	1	0
1-methyl-4-phenylpyridinium	low	1	0
ng-nitroarginine methyl ester	low	1	0
sufentanil	medium	3	2
enkephalin, methionine	low	2	0
paroxetine	medium	5	4
ethylcholine aziridinium	low	1	0
4-(n-methyl-n-nitrosamino)-1-(3-pyridyl)-1-butanone	low	3	0
simvastatin	medium	1	1
quinpirole	low	3	0
atomoxetine hydrochloride	low	3	0
mifepristone	low	1	0
fluorodopa f 18	low	2	0
salmeterol xinafoate	medium	1	1
naxagolide	low	1	0
aripiprazole	medium	3	1
atorvastatin	medium	1	1
duloxetine hydrochloride	low	1	0
adenosine	medium	1	1
carfentanil	low	2	0
venlafaxine hydrochloride	medium	3	2
glucose, (beta-d)-isomer	medium	1	1
norharman	low	1	0
n-acetylaspartic acid	low	1	0
aica ribonucleotide	low	1	0
triazoles	low	2	0
fluorodeoxyglucose f18	medium	7	4
sertraline	medium	1	1
acamprosate	medium	4	1
rivastigmine	medium	1	1
nicotine	medium	2,543	426
fibrinogen	medium	5	1
3,4-dihydroxyphenylglycol	low	1	0
homocysteine	low	1	0
sr141716	low	20	0
4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol	medium	7	3
(3h)2-carbomethoxy-3-(4-fluorophenyl)tropane	low	1	0
4-(methylnitrosoamino)-4-(3-pyridyl)-1-butanol	low	1	0
pregnenolone sulfate	low	1	0
epibatidine	low	9	0
methyllycaconitine	low	4	0
hydroxycotinine	medium	20	6
homoorientin	medium	1	1
s-(3-hydroxypropyl)cysteine n-acetate	medium	1	1
pramipexole	medium	3	2
reboxetine	low	1	0
isoarecolone	low	2	0
cilomilast	low	1	0
borneo	low	1	0
enkephalin, pen(2,5)-4-chloro-phe(4)-	low	1	0
resiquimod	low	1	0
guvacoline	low	1	0
technetium tc 99m pentetate	low	1	0
varenicline	medium	301	75
angiotensin ii	medium	1	1
atropine	low	1	0
organophosphonates	medium	2	1
antalarmin	low	1	0
pozanicline	low	1	0
3,7-diazabicyclo(3.3.1)nonane	low	1	0
cadmium metallothionein	low	1	0
anabasine	medium	4	1
bifeprunox	low	1	0
lenalidomide	medium	1	1
beta-methyl-6-chloromelatonin	low	1	0
ibogaine	low	3	0
bortezomib	medium	1	1
fibrin	low	1	0
oxytocin	medium	2	1
theanine	medium	1	1
inositol 3-phosphate	low	1	0
tretinoin	low	1	0
retinol	low	1	0
cocaine	medium	49	3
eicosapentaenoic acid	medium	2	2
gw 6471	low	2	0
zithromax	medium	1	1
benzoylecgonine	low	1	0
enkephalin, leucine	low	6	0
bromochloroacetic acid	low	1	0
deformylflustrabromine	low	2	0
isomethyleugenol	low	1	0
cannabidiol	medium	4	1
buprenorphine	medium	13	2
arginine vasopressin	low	1	0
propylthiouracil	medium	1	1
phenylthiourea	low	2	0
cotinine	medium	274	74
flunarizine	low	2	0
curcumin	low	1	0
thiohydantoins	medium	1	1
urb 597	low	2	0
capsaicin	low	1	0
chlorogenic acid	medium	1	1
thiourea	medium	2	1
D-fructopyranose	medium	6	4
unithiol	low	1	0
tamoxifen	low	1	0
6-methyl-2-(phenylethynyl)pyridine	low	3	0
lithium	low	1	0
nitrogen dioxide	low	1	0
raclopride	medium	8	3
quinine	low	1	0
nicotine n-glucuronide	low	1	0
cystine	low	2	0
u-50488	low	4	0
sch 23390	low	3	0
bp 897	low	2	0
freedom	low	2	0
noribogaine	low	2	0
l 663536	low	1	0
am 630	low	1	0
myelin basic protein	low	1	0
quercetin	low	1	0
bilirubin	low	2	0
vitexin	low	1	0
apigenin	low	1	0
luteolin	medium	1	1
beta carotene	low	2	0
harmine	medium	3	1
kava	medium	1	1
harman	medium	2	1
humulene	medium	48	5
anandamide	low	4	0
glyceryl 2-arachidonate	low	1	0
isotretinoin	low	1	0
thromboxane b2	low	1	0
n-oleoylethanolamine	low	1	0
naloxone	medium	11	1
oxycodone	low	1	0
topiramate	medium	7	4
lobeline	low	5	0
morphine	low	13	0
a 85380	low	2	0
3-(2,4-dimethoxybenzylidene)anabaseine	low	1	0
dexmedetomidine	medium	3	2
sb 277011	low	4	0
fluticasone	medium	1	1
mdl 100907	low	1	0
su 6656	low	1	0
lead	low	2	0
rubidium	low	1	0
aluminum	low	1	0
strontium	medium	1	1
bismuth	medium	1	1
arsenic	low	1	0
naltrexone	medium	36	11
dextromethorphan	low	2	0
sulfur	medium	1	1
cysteine	medium	2	1
silicon	low	1	0
heroin	low	3	0
norbinaltorphimine	low	2	0
enkephalin, ala(2)-mephe(4)-gly(5)-	low	2	0
pregabalin	medium	1	1
naltrindole	low	1	0
tetrodotoxin	low	1	0
radium	low	1	0
oxalates	low	1	0
palonosetron	low	1	0
dizocilpine maleate	low	2	0
n-oleoylglycine	low	1	0
sb 334867-a	low	3	0
hypericum	medium	2	1
r 121919	low	1	0
pentagastrin	medium	1	1
biphenyl-indanone a	low	1	0
lipid a	low	1	0
piperacillin	low	1	0
flb 457	low	1	0
n,n'-dodecane-1,12-diyl-bis-3-picolinium dibromide	low	2	0
aluminum oxide	medium	1	1
n-((1-allyl-2-pyrrolidinyl)methyl)-5-(3-fluoropropyl)-2,3-dimethoxybenzamide	low	3	0
am 1241	low	1	0
dianicline	low	1	0
bibw 2992	low	1	0
ly 379268	low	2	0
f-a 85380	medium	2	1
18-methoxycoronaridine	low	1	0
ro 16-0154	low	1	0
oxadiazoles	low	3	0
n-(3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamide	medium	2	1
pnu-282987	low	1	0
buprenorphine, naloxone drug combination	low	1	0
8-azabicyclo(3.2.1)octane, 3-(4-chlorophenyl)-8-methyl-2-(3-(4-methylphenyl)-5-isoxazolyl)-, hydrochloride (1:1), (1r,2s,3s,5s)-	low	1	0
carfilzomib	medium	1	1
lisdexamfetamine dimesylate	medium	1	1
lorcaserin	medium	4	1
losartan potassium	low	1	0
empagliflozin	medium	1	1
scopolamine hydrobromide	low	2	0
pituitrin	low	2	0
sazetidine-a	low	2	0
clove	low	2	0
acid phosphatase	low	1	0
cytochrome c-t	low	1	0
cosyntropin	low	1	0
cholecystokinin	low	2	0
dynorphins	low	3	0
atrial natriuretic factor	low	1	0
beta-endorphin	low	3	0
neuropeptide y	low	7	0
liraglutide	low	1	0
glucagon-like peptide 1	low	1	0
incretins	low	1	0
cellulose	medium	1	1
ro13-9904	low	3	0
sodium ethylxanthate	low	1	0
niraparib	medium	1	1
jzl 184	low	1	0
quetiapine fumarate	low	1	0
cardiovascular agents	medium	2	1
neurotensin	low	2	0
cerebellin	low	1	0
plx4032	medium	1	1
ly2456302	low	2	0
piperidines	medium	28	1
interleukin-8	low	2	0
exenatide	low	1	0
ascorbic acid	low	2	0
tetracycline	low	1	0
warfarin	low	1	0
phenprocoumon	low	1	0
byl719	medium	1	1
2'-hydroxy-5,9-dimethyl-2-allyl-6,7-benzomorphan	low	1	0
transforming growth factor beta	low	1	0
am4113	low	2	0
cyclin d1	low	1	0
vitamin b 12	low	1	0
aconitine	low	4	0
peptide yy	low	1	0
asbestos, amosite	low	1	0
thromboplastin	low	1	0
muramidase	low	1	0
tc 2559	low	1	0
exudates	medium	26	5

Protein Targets (2,721)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Sodium-dependent serotonin transporter	0	72	10	83
Sodium-dependent dopamine transporter	0	60	5	65
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	21	0	0	21
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	6	0	0	6
thioredoxin reductase	75	0	0	75
USP1 protein, partial	55	0	0	55
TDP1 protein	121	0	0	121
vitamin D3 receptor isoform VDRA	36	0	0	36
importin subunit beta-1 isoform 1	11	0	0	11
flap endonuclease 1	31	0	0	31
serine/threonine-protein kinase PLK1	7	0	0	7
snurportin-1	11	0	0	11
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	21	0	0	21
GTP-binding nuclear protein Ran isoform 1	8	0	0	8
DNA polymerase eta isoform 1	10	0	0	10
DNA polymerase iota isoform a (long)	34	0	0	34
urokinase-type plasminogen activator precursor	17	0	0	17
plasminogen precursor	17	0	0	17
urokinase plasminogen activator surface receptor precursor	17	0	0	17
geminin	88	0	0	88
DNA polymerase kappa isoform 1	34	0	0	34
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	2	2	4
Beta-lactamase	0	3	0	3
Transthyretin	0	2	3	6
Fatty acid-binding protein, intestinal	0	2	2	4
Fatty acid-binding protein, adipocyte	0	1	1	2
Cyclin-A2	0	3	0	3
Cannabinoid receptor 1	0	11	5	16
Cyclin-dependent kinase 2	0	6	5	11
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	2	2	4
Guanine nucleotide-binding protein G	9	0	0	9
Fatty acid-binding protein 5	0	0	1	1
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	2	3	5
Mitogen-activated protein kinase 14	0	9	4	13
Luciferase	32	0	0	32
RAR-related orphan receptor gamma	86	0	0	86
GLI family zinc finger 3	94	0	0	94
AR protein	110	0	0	110
nuclear receptor subfamily 1, group I, member 3	76	0	0	76
progesterone receptor	54	0	0	54
glucocorticoid receptor [Homo sapiens]	88	0	0	88
retinoic acid nuclear receptor alpha variant 1	87	0	0	87
retinoid X nuclear receptor alpha	68	0	0	68
farnesoid X nuclear receptor	48	0	0	48
pregnane X nuclear receptor	83	0	0	83
estrogen nuclear receptor alpha	125	0	0	125
peroxisome proliferator-activated receptor delta	61	0	0	61
peroxisome proliferator activated receptor gamma	61	0	0	61
vitamin D (1,25- dihydroxyvitamin D3) receptor	64	0	0	64
aryl hydrocarbon receptor	44	0	0	44
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	54	0	0	54
activating transcription factor 6	36	0	0	36
v-jun sarcoma virus 17 oncogene homolog (avian)	46	0	0	46
Histone H2A.x	32	0	0	32
thyroid hormone receptor beta isoform 2	96	0	0	96
heat shock protein beta-1	34	0	0	34
nuclear factor erythroid 2-related factor 2 isoform 1	84	0	0	84
Cellular tumor antigen p53	72	1	0	73
Solute carrier family 22 member 1	0	3	0	5
Solute carrier family 22 member 2	0	13	0	20
Solute carrier family 22 member 1	0	37	0	44
Solute carrier family 22 member 2	0	2	0	3
Solute carrier family 22 member 3	0	8	0	11
Solute carrier family 22 member 3	0	5	0	7
POU domain, class 2, transcription factor 2	0	0	0	1
Solute carrier family 22 member 1	0	14	0	20
Solute carrier family 22 member 2	0	12	0	17
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	38	0	0	38
Microtubule-associated protein tau	55	0	0	55
euchromatic histone-lysine N-methyltransferase 2	126	0	0	126
Bloom syndrome protein isoform 1	37	0	0	37
chromobox protein homolog 1	72	0	0	72
M-phase phosphoprotein 8	25	0	0	25
Chain A, SOLUBLE ACETYLCHOLINE RECEPTOR	0	0	1	1
Chain E, SOLUBLE ACETYLCHOLINE RECEPTOR	0	0	1	1
Chain A, Soluble acetylcholine receptor	0	0	1	1
Chain E, Soluble acetylcholine receptor	0	0	1	1
Chain A, SOLUBLE ACETYLCHOLINE RECEPTOR	0	0	1	1
Chain E, SOLUBLE ACETYLCHOLINE RECEPTOR	0	0	1	1
Chain F, SOLUBLE ACETYLCHOLINE RECEPTOR	0	0	1	1
Chain J, SOLUBLE ACETYLCHOLINE RECEPTOR	0	0	1	1
Acetylcholine receptor subunit alpha	0	9	4	13
Acetylcholine receptor subunit gamma	0	9	4	13
Neuronal acetylcholine receptor subunit alpha-4	4	25	10	41
Acetylcholine receptor subunit beta	0	9	4	13
Neuronal acetylcholine receptor subunit beta-2	4	25	10	41
Neuronal acetylcholine receptor subunit beta-2	0	18	8	29
Neuronal acetylcholine receptor subunit beta-4	0	10	5	17
Neuronal acetylcholine receptor subunit alpha-3	0	10	6	17
Neuronal acetylcholine receptor subunit alpha-7	0	12	8	20
Neuronal acetylcholine receptor subunit alpha-4	0	18	8	28
Acetylcholine-binding protein	0	1	2	3
Neuronal acetylcholine receptor subunit alpha-7	0	16	8	25
Acetylcholine receptor subunit delta	0	9	4	13
pregnane X receptor	17	0	0	17
phosphopantetheinyl transferase	48	0	0	48
SMAD family member 2	25	0	0	25
SMAD family member 3	25	0	0	25
caspase 7, apoptosis-related cysteine protease	22	0	0	22
aldehyde dehydrogenase 1 family, member A1	69	0	0	69
estrogen-related nuclear receptor alpha	101	0	0	101
caspase-3	22	0	0	22
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	37	0	0	37
thyroid hormone receptor beta isoform a	33	0	0	33
Voltage-dependent calcium channel gamma-2 subunit	40	0	0	40
Cytochrome P450 1A2	0	21	3	26
Tyrosine-protein kinase Lck	0	6	4	10
Tyrosine-protein kinase Fyn	0	10	4	14
Aldo-keto reductase family 1 member B1	0	47	0	47
Adenosine receptor A3	0	29	3	33
Alpha-1B adrenergic receptor	0	55	6	61
Glutamate receptor 2	42	6	3	52
Acetylcholinesterase	0	29	3	34
Sodium-dependent noradrenaline transporter	0	69	10	79
Aryl hydrocarbon receptor	0	0	3	3
Alpha-1A adrenergic receptor	0	62	8	70
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	54	0	0	54
Chain A, HADH2 protein	35	0	0	35
Chain B, HADH2 protein	35	0	0	35
Chain A, 2-oxoglutarate Oxygenase	41	0	0	41
Chain A, Protocatechuate 3,4-dioxygenase	0	0	1	1
Chain M, Protocatechuate 3,4-dioxygenase	0	0	1	1
Olfactory receptor class A-like protein 1	0	0	1	1
endonuclease IV	10	0	0	10
RGS12	4	0	0	4
NFKB1 protein, partial	24	0	0	24
GLS protein	57	0	0	57
Thrombopoietin	15	0	0	15
alkaline phosphatase, intestinal	0	1	1	2
thioredoxin glutathione reductase	10	0	0	10
apical membrane antigen 1, AMA1	13	0	0	13
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	23	0	0	23
thyroid stimulating hormone receptor	63	0	0	63
hypothetical protein, conserved	6	0	0	6
regulator of G-protein signaling 4	56	0	0	56
lysosomal alpha-glucosidase preproprotein	13	0	0	13
peripheral myelin protein 22 isoform 1	21	0	0	21
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	2	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	32	0	0	32
intestinal alkaline phosphatase precursor	0	2	0	2
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	4	0	0	4
DNA polymerase beta	13	0	0	13
alkaline phosphatase, germ cell type preproprotein	0	1	1	2
POsterior Segregation	0	0	3	3
muscarinic acetylcholine receptor M1	50	0	0	50
lamin isoform A-delta10	87	0	0	87
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Zinc finger protein mex-5	0	0	3	3
ATP-dependent phosphofructokinase	50	0	0	50
5-hydroxytryptamine receptor 2C	0	33	7	40
5-hydroxytryptamine receptor 2A	0	38	9	47
5-hydroxytryptamine receptor 1A	0	61	7	69
Sodium-dependent dopamine transporter	0	29	5	34
5-hydroxytryptamine receptor 1B	0	43	5	48
5-hydroxytryptamine receptor 1D	0	14	5	19
5-hydroxytryptamine receptor 1F	0	14	5	19
5-hydroxytryptamine receptor 2B	0	30	7	37
5-hydroxytryptamine receptor 6	0	7	5	12
Sodium-dependent serotonin transporter	0	26	6	33
5-hydroxytryptamine receptor 7	0	15	5	20
5-hydroxytryptamine receptor 5A	0	7	5	12
5-hydroxytryptamine receptor 5B	0	7	5	12
5-hydroxytryptamine receptor 3A	0	10	5	15
5-hydroxytryptamine receptor 4	0	7	5	12
5-hydroxytryptamine receptor 3B	0	10	5	15
ATAD5 protein, partial	44	0	0	44
cytochrome P450 2D6 isoform 1	44	0	0	44
cytochrome P450 2C19 precursor	38	0	0	38
D(1A) dopamine receptor	45	0	0	45
atrial natriuretic peptide receptor 1 precursor	10	0	0	10
atrial natriuretic peptide receptor 2 precursor	14	0	0	14
ras-related protein Rab-9A	14	0	0	14
serine/threonine-protein kinase mTOR isoform 1	29	0	0	29
histone acetyltransferase KAT2A isoform 1	33	0	0	33
D(1A) dopamine receptor	18	3	0	21
Nrf2	4	0	0	4
15-lipoxygenase, partial	22	0	0	22
EWS/FLI fusion protein	55	0	0	56
luciferase	1	0	0	1
Parkin	12	0	0	12
pyruvate kinase	4	0	0	4
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	14	0	0	14
beta-2 adrenergic receptor	5	0	1	6
NPC intracellular cholesterol transporter 1 precursor	12	0	0	12
cellular tumor antigen p53 isoform a	29	0	0	29
cytochrome P450 2C9 precursor	28	0	0	28
nuclear receptor ROR-gamma isoform 1	37	0	0	37
survival motor neuron protein isoform d	34	0	0	34
cytochrome P450 3A4 isoform 1	56	0	0	56
pyruvate kinase PKM isoform b	3	0	0	3
Metabotropic glutamate receptor 8	0	4	1	6
Gamma-aminobutyric acid receptor subunit pi	56	22	2	80
Metabotropic glutamate receptor 6	0	3	3	8
Integrin beta-3	26	1	1	28
Integrin alpha-IIb	26	1	1	28
Luciferin 4-monooxygenase	0	1	0	1
Cytochrome P450 3A4	0	41	6	52
Ornithine decarboxylase	3	0	0	4
Cytochrome P450 2D6	0	30	3	37
Gamma-aminobutyric acid receptor subunit beta-1	56	22	2	80
Gamma-aminobutyric acid receptor subunit delta	56	22	2	80
Gamma-aminobutyric acid receptor subunit gamma-2	56	22	4	82
Gamma-aminobutyric acid receptor subunit alpha-5	56	22	2	80
Gamma-aminobutyric acid receptor subunit alpha-3	56	22	2	80
Metabotropic glutamate receptor 1	0	4	2	6
Gamma-aminobutyric acid receptor subunit gamma-1	56	22	2	80
Gamma-aminobutyric acid receptor subunit alpha-2	56	22	2	80
Gamma-aminobutyric acid receptor subunit alpha-4	56	22	2	80
Gamma-aminobutyric acid receptor subunit gamma-3	56	22	2	80
Gamma-aminobutyric acid receptor subunit alpha-6	56	22	2	80
Metabotropic glutamate receptor 5	0	4	2	6
Metabotropic glutamate receptor 5	0	5	3	10
Histamine H2 receptor	42	4	1	54
Gamma-aminobutyric acid receptor subunit alpha-1	56	24	4	84
Gamma-aminobutyric acid receptor subunit beta-3	56	22	2	80
Gamma-aminobutyric acid receptor subunit beta-2	56	22	4	82
Glutamate receptor ionotropic, NMDA 2B	0	11	1	12
Metabotropic glutamate receptor 1	0	5	3	10
Metabotropic glutamate receptor 2	0	5	6	13
Metabotropic glutamate receptor 7	0	3	2	7
Metabotropic glutamate receptor 3	0	3	2	7
Metabotropic glutamate receptor 4	0	4	3	9
Amine oxidase [flavin-containing] A	0	1	0	2
GABA theta subunit	56	22	2	80
Ataxin-2	50	0	0	50
Gamma-aminobutyric acid receptor subunit epsilon	56	22	2	80
phosphoglycerate kinase	4	0	0	4
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	3	0	0	3
Chain A, Avidin	0	0	2	2
Chain A, Avidin	0	0	2	2
Chain B, Avidin	0	0	2	2
cytochrome P450 2D6	60	0	0	60
Acetylcholine receptor subunit alpha	0	5	1	6
Neuronal acetylcholine receptor subunit alpha-3	0	16	7	25
Neuronal acetylcholine receptor subunit alpha-2	0	10	4	15
Neuronal acetylcholine receptor subunit beta-3	0	8	5	14
Neuronal acetylcholine receptor subunit beta-4	0	16	7	25
Neuronal acetylcholine receptor subunit alpha-5	0	7	4	12
Neuronal acetylcholine receptor subunit alpha-6	0	9	5	15
Neuronal acetylcholine receptor subunit alpha-9	0	7	4	12
Neuronal acetylcholine receptor subunit alpha-10	0	7	4	12
acetylcholinesterase	36	0	0	36
hypoxia-inducible factor 1 alpha subunit	30	0	0	30
estrogen receptor 2 (ER beta)	49	0	0	49
thyroid stimulating hormone receptor	43	0	0	43
thyrotropin-releasing hormone receptor	11	0	0	11
Caspase-7	15	0	0	15
caspase-3	15	0	0	15
ATPase family AAA domain-containing protein 5	30	0	0	30
Chain A, ATP-DEPENDENT DNA HELICASE Q1	11	0	0	11
dopamine D1 receptor	11	0	0	11
arylsulfatase A	48	0	0	48
peripheral myelin protein 22	52	0	0	52
Histone deacetylase 3	0	10	0	10
Solute carrier family 22 member 6	0	5	0	5
Histone deacetylase 4	0	9	0	9
Histone deacetylase 1	0	12	0	12
Histone deacetylase 7	0	9	0	9
Histone deacetylase 2	0	12	0	12
Polyamine deacetylase HDAC10	0	8	0	8
Histone deacetylase 11	0	8	0	8
Histone deacetylase 8	0	11	0	11
Histone deacetylase 6	0	11	0	11
Histone deacetylase 9	0	9	0	9
Histone deacetylase 5	0	9	0	9
Choline O-acetyltransferase	0	3	0	4
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
signal transducer and activator of transcription 6, interleukin-4 induced	3	0	0	3
NPYLR7B	0	0	2	2
IDH1	32	0	0	32
glycogen synthase kinase-3 beta isoform 1	0	0	3	3
mitogen-activated protein kinase 1	35	0	0	35
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	4	4
Sodium/nucleoside cotransporter 2	0	2	0	2
Rap guanine nucleotide exchange factor 3	11	0	0	11
Purine nucleoside phosphorylase	0	1	0	1
Epidermal growth factor receptor	0	13	5	18
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	4	0	4
Receptor tyrosine-protein kinase erbB-2	0	8	3	11
Insulin receptor	0	1	4	6
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	2	4	7
Platelet-derived growth factor receptor beta	0	2	4	7
Heat shock 70 kDa protein 1A	0	2	1	3
Heat shock cognate 71 kDa protein	0	0	2	2
Fibroblast growth factor receptor 1	0	2	4	7
Inosine-5'-monophosphate dehydrogenase 2	0	1	4	5
Endoplasmin	0	1	1	3
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	2	3
Fibroblast growth factor receptor 4	0	0	2	3
Fibroblast growth factor receptor 3	0	0	2	3
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenosine receptor A1	0	12	2	20
Adenosine receptor A3	0	3	0	3
Adenosine receptor A2a	0	11	7	21
Adenosine receptor A2b	0	2	1	6
Adenosine receptor A2b	0	4	2	8
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenosine receptor A1	0	10	4	19
Adenosine receptor A2a	0	10	4	22
Adenylate kinase isoenzyme 1	0	1	0	1
Phosphatidylinositol 4-kinase alpha	0	5	0	6
Adenosine receptor A1	0	2	1	3
Adenosine kinase	0	0	4	5
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Phosphatidylinositol 4-kinase type 2-beta	0	5	0	6
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	4	0	4
Phosphatidylinositol 4-kinase type 2-alpha	0	5	0	6
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
Phosphatidylinositol 4-kinase beta	0	5	2	8
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	3	0	3
Mu-type opioid receptor	0	38	16	63
Delta-type opioid receptor	0	28	11	48
Kappa-type opioid receptor	0	34	11	56
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	1	1	2
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Inositol monophosphatase 1	27	0	0	27
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 11	0	0	1	1
P2Y purinoceptor 12	0	1	1	2
Sensor protein kinase WalK	0	1	0	1
P2X purinoceptor 2	0	0	1	1
Chain A, Cruzipain	24	0	0	24
lethal factor (plasmid)	37	0	0	37
Polyamine oxidase 1	0	1	0	1
Alpha-2B adrenergic receptor	0	24	4	28
Alpha-2C adrenergic receptor	0	24	4	28
Alpha-2A adrenergic receptor	0	25	4	29
Nischarin	0	3	0	3
Deoxyhypusine synthase	0	1	0	1
Fructose-1,6-bisphosphatase 1	0	2	0	3
Bifunctional purine biosynthesis protein ATIC	0	1	0	2
Histidine triad nucleotide-binding protein 1	0	0	1	1
Chain A, Beta-lactamase	23	0	0	23
glp-1 receptor, partial	24	0	0	24
Fumarate hydratase	31	0	0	31
polyprotein	31	0	0	31
67.9K protein	30	0	0	30
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	25	0	0	26
transcriptional regulator ERG isoform 3	10	0	0	10
histone deacetylase 9 isoform 3	7	0	0	7
Vif	0	0	0	1
muscleblind-like protein 1 isoform 1	9	0	0	9
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	0	0	4
neuropeptide S receptor isoform A	17	0	0	17
ATP-binding cassette sub-family C member 3	0	81	0	81
Multidrug resistance-associated protein 4	0	83	0	86
Bile salt export pump	0	114	0	114
Interferon beta	61	0	0	61
Methionine aminopeptidase	0	1	0	1
Fatty-acid amide hydrolase 1	0	11	0	12
Canalicular multispecific organic anion transporter 1	0	77	0	77
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	2	0	2
Nitric oxide synthase, endothelial	0	2	0	2
Nitric oxide synthase, brain	0	3	0	4
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	2	1	5
Kappa-type opioid receptor	0	22	2	28
Mu-type opioid receptor	0	23	6	32
Tyrosine-protein kinase	0	0	1	1
glucocerebrosidase	18	0	0	18
alpha-galactosidase	9	0	0	9
Carboxylic ester hydrolase	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	5	0	5
Cytochrome P450 1A1	0	11	2	13
ATP-dependent translocase ABCB1	0	32	4	51
Cytochrome P450 2A6	0	11	2	14
Aromatase	0	8	0	8
Cytochrome P450 3A6	0	1	0	1
Cytochrome P450 2C9	0	27	1	29
UDP-glucuronosyltransferase 2B7	0	6	0	8
UDP-glucuronosyltransferase 1-6	0	5	0	5
Cytochrome P450 2B6	0	7	2	11
Substance-K receptor	0	12	0	12
UDP-glucuronosyltransferase 1A1	0	8	0	10
UDP-glucuronosyltransferase 1A4	0	5	0	11
Thromboxane-A synthase	0	2	0	2
Aryl hydrocarbon receptor	0	1	0	1
Cytochrome P450 2C19	0	16	1	19
Multidrug resistance-associated protein 1	0	6	1	9
UDP-glucuronosyltransferase 2B10	0	5	0	5
DNA-dependent protein kinase catalytic subunit	0	4	0	4
Xanthine dehydrogenase/oxidase	0	7	0	9
Cytochrome P450 1B1	0	14	2	17
Histamine H3 receptor	0	2	0	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	17	2	20
Cannabinoid receptor 1	0	21	7	35
Cannabinoid receptor 2	0	17	6	29
Cannabinoid receptor 2	0	4	1	5
bromodomain adjacent to zinc finger domain 2B	21	0	0	21
Androgen receptor	0	12	0	12
PPM1D protein	23	0	0	23
Polyunsaturated fatty acid lipoxygenase ALOX15B	23	1	0	24
Cannabinoid receptor 2	0	2	5	7
aryl hydrocarbon receptor nuclear translocator	0	0	0	2
transforming acidic coiled-coil-containing protein 3	0	0	0	2
TAR DNA-binding protein 43	17	0	0	17
Glutaminyl-peptide cyclotransferase	0	3	0	3
Guanine deaminase	0	3	0	3
Phenylethanolamine N-methyltransferase	0	3	0	3
Substance-P receptor	0	3	0	3
Cytochrome P450 2A5	0	3	0	4
Sigma non-opioid intracellular receptor 1	0	15	0	15
Beta-2 adrenergic receptor	0	6	1	8
Sigma non-opioid intracellular receptor 1	0	13	3	16
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	0	1
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Carbonic anhydrase 1	0	26	0	36
Carbonic anhydrase 2	0	27	2	40
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-lactamase OXA-7	0	0	0	1
Solute carrier family 15 member 1	0	3	0	3
Solute carrier family 15 member 1	0	2	0	2
Spike glycoprotein	39	4	6	49
10 kDa heat shock protein, mitochondrial	0	4	0	4
Angiopoietin-1 receptor	0	1	3	4
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Thiosulfate sulfurtransferase	0	4	0	4
Metallo-beta-lactamase VIM-13	0	0	0	1
Efflux transporter	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase Toho-1	0	0	0	1
Beta-lactamase	0	0	0	1
Class D beta-lactamase	0	0	0	1
60 kDa chaperonin	0	4	0	4
Metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
10 kDa chaperonin	0	4	0	4
Metallo-b-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Beta-lactamase class B VIM-2	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
Chain A, Ferritin light chain	30	0	0	30
Fatty-acid amide hydrolase 1	0	7	0	7
Fatty-acid amide hydrolase 1	0	1	0	2
Potassium channel subfamily K member 3	0	2	0	2
Fatty acid-binding protein, liver	0	6	0	6
Glutamate receptor 1	2	6	3	12
Glutamate receptor 3	2	6	3	12
Glutamate receptor 4	2	6	3	12
Cannabinoid receptor 1	0	5	3	8
Corticotropin-releasing factor receptor 2	0	4	0	4
Lanosterol 14-alpha demethylase	0	3	0	3
Potassium channel subfamily K member 2	0	2	0	2
Transient receptor potential cation channel subfamily V member 1	0	3	5	10
Transient receptor potential cation channel subfamily V member 2	0	5	2	7
Atrial natriuretic peptide receptor 3	0	1	0	1
Type-1A angiotensin II receptor	0	3	1	4
Type-1 angiotensin II receptor	0	0	1	1
Type-1B angiotensin II receptor	0	4	0	4
Type-1 angiotensin II receptor	0	3	3	6
Type-2 angiotensin II receptor	0	3	0	3
Type-2 angiotensin II receptor	0	2	0	2
Corticotropin-releasing factor receptor 1	0	4	1	5
Corticotropin-releasing factor receptor 1	0	2	0	3
Corticotropin-releasing factor receptor 2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	20	0	0	20
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	2	0	2
Chain A, Transthyretin	0	0	2	2
Chain A, Transthyretin	0	0	2	2
Chain A, Transthyretin	0	0	2	2
Chain A, Transthyretin	0	0	2	2
Chain B, Transthyretin	0	0	2	2
Chain A, Transthyretin	0	0	2	2
Chain B, Transthyretin	0	0	2	2
Chain A, Casein kinase II subunit alpha	0	2	0	2
Chain A, Casein kinase II subunit alpha	0	2	0	2
Chain A, Casein Kinase Ii Subunit Alpha	0	2	0	2
interleukin 8	13	0	0	13
BRCA1	2	0	0	2
Smad3	23	0	0	23
cytochrome P450 family 3 subfamily A polypeptide 4	72	0	0	72
G	40	0	0	40
Neuraminidase	0	7	0	7
Replicase polyprotein 1ab	0	5	6	11
hemoglobin subunit beta	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	11	0	0	11
ubiquitin carboxyl-terminal hydrolase 2 isoform a	11	0	0	11
Gamma-aminobutyric acid receptor subunit pi	0	13	0	13
Gamma-aminobutyric acid receptor subunit delta	0	13	0	13
Polyphenol oxidase 2	0	7	1	12
Aldo-keto reductase family 1 member B10	0	4	0	4
G2/mitotic-specific cyclin-B2	0	4	0	4
Poly [ADP-ribose] polymerase tankyrase-1	0	3	0	3
Lysozyme C-1	0	1	0	1
Cationic trypsin	0	3	0	3
HLA class I histocompatibility antigen, B alpha chain	40	0	0	40
Estrogen receptor	1	7	3	12
Glucocorticoid receptor	1	6	3	14
Amyloid-beta precursor protein	2	13	0	16
Myeloperoxidase	0	8	0	8
Cyclin-dependent kinase 1	0	5	4	9
Beta-glucuronidase	0	1	0	1
Seed linoleate 13S-lipoxygenase-1	0	6	0	12
Neutrophil elastase	0	8	0	8
Poly [ADP-ribose] polymerase 1	0	5	2	9
Replicase polyprotein 1a	0	5	6	11
Replicase polyprotein 1ab	0	5	6	11
Replicase polyprotein 1ab	0	14	7	21
Replicase polyprotein 1ab	0	15	8	23
Androgen receptor	1	3	1	7
Sialidase	0	3	0	3
Serine/threonine-protein kinase pim-1	0	4	5	10
Angiotensin-converting enzyme	0	36	0	36
Cystic fibrosis transmembrane conductance regulator	0	2	2	4
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Pyruvate kinase PKM	0	1	1	2
G2/mitotic-specific cyclin-B1	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	15	5	20
Urease subunit alpha	0	6	0	6
Aldo-keto reductase family 1 member B1	0	8	0	8
G2/mitotic-specific cyclin-B	0	3	0	3
Mucin-1	0	1	0	1
Glycogen synthase kinase-3 beta	0	4	0	4
Gamma-aminobutyric acid receptor subunit beta-1	0	14	2	16
Gamma-aminobutyric acid receptor subunit gamma-2	0	14	4	18
Casein kinase II subunit alpha'	0	5	4	9
Amine oxidase [flavin-containing] A	0	22	0	24
Carbonic anhydrase 4	0	15	0	21
Amine oxidase [flavin-containing] B	0	18	1	20
Dipeptidyl peptidase 4	0	5	1	6
Proteasome subunit beta type-5	0	7	0	9
Gamma-aminobutyric acid receptor subunit beta-3	0	15	4	19
Substance-P receptor	0	8	0	9
Gamma-aminobutyric acid receptor subunit alpha-5	0	15	5	20
Gamma-aminobutyric acid receptor subunit alpha-3	0	15	4	19
Prostaglandin G/H synthase 2	0	14	3	18
Receptor-type tyrosine-protein kinase FLT3	0	6	4	10
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
17-beta-hydroxysteroid dehydrogenase type 2	0	3	0	3
Acetylcholinesterase	0	5	0	5
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Homeobox protein Nkx-2.5	0	2	0	2
Tyrosine-protein kinase SYK	0	4	7	11
Gamma-aminobutyric acid receptor subunit alpha-2	0	15	3	18
Gamma-aminobutyric acid receptor subunit beta-2	0	14	3	17
Xanthine dehydrogenase/oxidase	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	0	14	2	16
Glycogen synthase kinase-3 alpha	0	5	4	9
Glycogen synthase kinase-3 beta	0	10	5	15
Estrogen receptor	0	0	1	1
Nuclear receptor ROR-gamma	21	1	1	23
Death-associated protein kinase 1	0	3	2	5
Mitogen-activated protein kinase 10	0	3	6	9
Beta-secretase 1	0	9	0	10
Casein kinase II subunit beta	0	5	0	5
Casein kinase II subunit alpha	0	6	2	8
Urease subunit beta	0	6	0	6
Gamma-aminobutyric acid receptor subunit epsilon	0	13	0	13
Disintegrin and metalloproteinase domain-containing protein 17	9	0	0	9
Lactoperoxidase	0	2	0	3
MO15-related protein kinase Pfmrk	0	2	0	2
Cyclin-dependent kinase 6	0	4	4	8
Cyclin-dependent-like kinase 5	0	4	4	8
Cyclin homolog	0	3	0	3
Transcription factor GATA-4	0	2	0	2
Cyclin-dependent kinase 5 activator 1	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	14	2	16
Carbonic anhydrase 3	0	3	0	3
Substance-K receptor	0	4	0	4
Reverse transcriptase/RNaseH	0	1	0	2
Integrase	0	5	0	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	13	0	13
Casein kinase II subunit alpha 3	0	4	0	4
Inositol polyphosphate multikinase	0	3	0	3
G2/mitotic-specific cyclin-B3	0	4	0	4
Inositol hexakisphosphate kinase 1	40	0	0	40
Estrogen receptor beta	1	6	3	10
Enoyl-acyl-carrier protein reductase	0	5	0	5
Aurora kinase B	0	4	4	8
NACHT, LRR and PYD domains-containing protein 3	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	13	0	13
Myocilin	0	0	1	1
Cyclin-dependent kinase 1	0	3	0	3
Prenyltransferase homolog	0	0	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	4	2	6
MAP kinase-interacting serine/threonine-protein kinase 2	0	3	2	5
Carboxylic ester hydrolase	0	4	0	5
NADPH oxidase 4	0	3	0	3
Dipeptidyl peptidase 3	0	3	0	3
Estrogen receptor beta	0	0	1	1
Inositol hexakisphosphate kinase 2	0	3	0	3
Short transient receptor potential channel 5	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	13	0	13
Sialidase-2	0	3	0	3
cytochrome P450 2C9, partial	40	0	0	40
potassium voltage-gated channel subfamily H member 2 isoform d	44	0	0	44
5-hydroxytryptamine receptor 1A	0	27	13	40
Tryptophan 5-hydroxylase 1	0	4	0	4
D(2) dopamine receptor	0	59	10	78
D	0	24	0	27
D(3) dopamine receptor	0	26	2	30
D(2) dopamine receptor	0	9	0	9
D(1A) dopamine receptor	0	44	5	54
D(4) dopamine receptor	0	33	5	45
D(1B) dopamine receptor	0	13	1	18
Alpha-1D adrenergic receptor	0	33	6	39
D(1B) dopamine receptor	0	13	0	13
5-hydroxytryptamine receptor 2A	0	60	9	73
D(4) dopamine receptor	0	15	1	16
D(3) dopamine receptor	0	56	9	73
5-hydroxytryptamine receptor 7	0	17	0	17
D(2) dopamine receptor	0	43	9	56
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	4	0	4
D	0	10	0	10
Sigma non-opioid intracellular receptor 1	0	49	1	50
Glutamate receptor ionotropic, NMDA 1	0	25	4	36
Muscarinic acetylcholine receptor M2	0	33	5	42
Muscarinic acetylcholine receptor M4	0	34	3	39
Muscarinic acetylcholine receptor M1	0	17	5	26
Muscarinic acetylcholine receptor M3	0	15	5	24
Muscarinic acetylcholine receptor M4	0	16	5	25
Muscarinic acetylcholine receptor M5	0	15	5	24
Muscarinic acetylcholine receptor M5	0	34	2	38
Muscarinic acetylcholine receptor M2	0	18	6	29
Muscarinic acetylcholine receptor M1	0	38	5	47
Muscarinic acetylcholine receptor M1	0	1	2	5
Muscarinic acetylcholine receptor M3	0	37	4	43
Muscarinic acetylcholine receptor	0	2	2	5
Muscarinic acetylcholine receptor M3	0	0	2	4
Muscarinic acetylcholine receptor M2	0	0	1	4
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Nitric oxide synthase, endothelial	0	1	0	3
Nitric oxide synthase, inducible	0	2	0	3
Cationic amino acid transporter 3	0	2	0	2
Translocator protein	0	6	3	10
Vasopressin V2 receptor	0	4	2	7
Oxytocin receptor	0	3	3	6
Vasopressin V1a receptor	0	1	2	3
Vasopressin V1a receptor	0	4	3	7
Vasopressin V1b receptor	0	2	2	4
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	2	1	4
Translocator protein	0	1	0	2
Oxytocin receptor	0	2	0	2
Vasopressin V2 receptor	0	2	1	3
5-hydroxytryptamine receptor 3E	0	6	0	6
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
5-hydroxytryptamine receptor 3A	0	2	1	3
5-hydroxytryptamine receptor 3B	0	7	1	8
Alpha-2C adrenergic receptor	0	45	4	51
Alpha-1D adrenergic receptor	0	46	3	53
5-hydroxytryptamine receptor 2C	0	63	6	70
Histamine H1 receptor	0	9	2	12
5-hydroxytryptamine receptor 7	0	14	1	15
Alpha-1A adrenergic receptor	0	17	4	27
Histamine H1 receptor	0	39	7	49
Alpha-1B adrenergic receptor	0	13	3	20
5-hydroxytryptamine receptor 2B	0	66	4	71
5-hydroxytryptamine receptor 3A	0	11	1	12
5-hydroxytryptamine receptor 6	0	40	1	42
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	6	0	6
Potassium voltage-gated channel subfamily H member 2	0	65	0	65
5-hydroxytryptamine receptor 3D	0	6	0	6
Multidrug and toxin extrusion protein 2	0	7	0	7
5-hydroxytryptamine receptor 3C	0	6	0	6
Multidrug and toxin extrusion protein 1	0	11	0	11
Histamine H3 receptor	0	11	2	13
Chain A, Hyaluronidase, phage associated	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	3	0	4
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	7	0	7
Alpha-2B adrenergic receptor	0	58	3	63
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	1	1	3
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	2
Solute carrier family 23 member 1	0	1	0	1
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	2	0	2
5-hydroxytryptamine receptor 1D	0	5	0	7
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	23	4	34
Glutamate receptor ionotropic, NMDA 2B	0	25	4	36
Glutamate receptor ionotropic, NMDA 2C	0	23	4	35
Carbonic anhydrase-like protein, putative	0	0	0	8
Glutamate receptor ionotropic, NMDA 2D	0	23	4	34
Glutamate receptor ionotropic, NMDA 3B	0	23	4	34
Carbonic anhydrase 4	0	4	0	6
Glutamate receptor ionotropic, NMDA 3A	0	23	4	34
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Prostaglandin G/H synthase 2	0	3	0	3
Fatty acid-binding protein, liver	0	4	2	6
Prostaglandin G/H synthase 1	0	10	0	10
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	9	0	10
Urotensin-2 receptor	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	2	0	2
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	4	0	4
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Solute carrier organic anion transporter family member 2B1	0	2	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	4	0	4
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	6	0	10
Solute carrier organic anion transporter family member 1B1	0	11	0	16
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	3	3
5-hydroxytryptamine receptor 4	0	48	2	50
Muscarinic acetylcholine receptor M4	0	3	1	5
Gamma-aminobutyric acid type B receptor subunit 2	0	3	2	5
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	3	2	5
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Chain A, Integrase	0	1	0	1
Chain A, Integrase	0	1	0	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, GCN4P1	0	0	1	1
Chain B, GCN4P1	0	0	1	1
Chain C, GCN4P1	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, T4 LYSOZYME	0	0	1	1
Chain A, Replicase polyprotein 1ab	0	1	0	1
Chain A, 3C-like proteinase	0	1	0	1
Endolysin	0	0	3	3
DNA dC->dU-editing enzyme APOBEC-3F isoform a	4	0	0	4
core protein, partial	0	1	0	1
Leukotriene C4 synthase	0	0	2	2
Bone morphogenetic protein receptor type-1B	0	0	4	4
Membrane-associated progesterone receptor component 1	0	0	4	4
Cell division cycle 7-related protein kinase	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	2	2	4
Serine/threonine-protein kinase PLK4	0	1	4	5
Serine/threonine-protein kinase 25	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Pyridoxal kinase	0	0	4	4
Citron Rho-interacting kinase	0	0	4	4
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	4	4
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	2	3
Peripheral plasma membrane protein CASK	0	0	2	2
Aurora kinase A	0	1	4	5
Cyclin-G-associated kinase	0	0	4	4
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	2	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 3	0	0	4	4
3-phosphoinositide-dependent protein kinase 1	0	1	2	3
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	1	4	5
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	3	3
NUAK family SNF1-like kinase 1	0	1	2	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Tyrosine-protein kinase JAK2	0	0	3	3
Rho-associated protein kinase 2	0	0	4	4
Serine/threonine-protein kinase ULK1	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	4	4
Ribosomal protein S6 kinase alpha-5	0	0	4	4
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	4	4
Ribosomal protein S6 kinase alpha-4	0	0	4	4
Serine/threonine-protein kinase 16	0	0	4	4
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	4	4
Serine/threonine-protein kinase D3	0	3	4	7
Cyclin-dependent kinase 14	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 6	0	0	4	4
Serine/threonine-protein kinase OSR1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	4	4
Serine/threonine-protein kinase LATS1	0	0	4	4
Serine/threonine-protein kinase PAK 4	0	0	4	4
Serine/threonine-protein kinase Chk2	0	0	2	2
Tyrosine-protein kinase ABL1	0	5	4	10
RAF proto-oncogene serine/threonine-protein kinase	0	3	3	7
High affinity nerve growth factor receptor	0	0	3	3
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	3	3
ADP/ATP translocase 2	0	0	4	4
Cytochrome P450 2E1	0	2	0	2
Protein kinase C beta type	0	3	4	7
Glycogen phosphorylase, liver form	0	2	4	6
Tyrosine-protein kinase Fes/Fps	0	0	4	4
Macrophage colony-stimulating factor 1 receptor	0	1	2	3
Adenine phosphoribosyltransferase	0	0	4	4
Tyrosine-protein kinase Yes	0	3	4	7
Tyrosine-protein kinase Lyn	0	2	4	6
Proto-oncogene tyrosine-protein kinase receptor Ret	0	5	4	9
Insulin-like growth factor 1 receptor	0	2	4	6
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	4	4
Hepatocyte growth factor receptor	0	2	4	6
Tyrosine-protein kinase HCK	0	1	4	5
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Tyrosine-protein kinase Fgr	0	0	3	3
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Serine/threonine-protein kinase A-Raf	0	2	4	6
Cytochrome P450 2C8	0	11	2	13
Mast/stem cell growth factor receptor Kit	0	2	2	4
Glycogen phosphorylase, brain form	0	0	4	4
Breakpoint cluster region protein	0	1	4	6
DNA topoisomerase 2-alpha	0	0	4	4
Cyclin-dependent kinase 4	0	2	4	6
ADP/ATP translocase 3	0	0	4	4
Proto-oncogene tyrosine-protein kinase Src	0	5	4	9
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	4	4
Insulin receptor-related protein	0	0	2	2
Serine/threonine-protein kinase B-raf	0	5	6	12
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	4	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	4	4	8
Platelet-derived growth factor receptor alpha	0	2	2	4
Tyrosine-protein kinase Fer	0	0	4	4
Protein kinase C alpha type	0	3	4	7
cAMP-dependent protein kinase catalytic subunit alpha	0	1	4	5
Vascular endothelial growth factor receptor 1	0	3	2	5
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	4	4
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Ras-related protein Rab-6A	0	0	4	4
Serine/threonine-protein kinase MAK	0	0	2	2
Cyclin-dependent kinase 11B	0	0	2	2
Ephrin type-A receptor 1	0	0	4	4
Receptor tyrosine-protein kinase erbB-3	0	1	2	3
Multifunctional protein ADE2	0	0	4	4
cAMP-dependent protein kinase catalytic subunit gamma	0	1	3	4
cAMP-dependent protein kinase catalytic subunit beta	0	1	4	5
Ferrochelatase, mitochondrial	0	0	5	5
Ribosomal protein S6 kinase beta-1	0	0	4	4
Tyrosine-protein kinase JAK1	0	0	4	4
Protein kinase C eta type	0	3	2	5
Beta-adrenergic receptor kinase 1	0	1	5	6
Probable ATP-dependent RNA helicase DDX6	0	0	4	4
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	2	4	6
MAP/microtubule affinity-regulating kinase 3	0	0	4	4
Deoxycytidine kinase	0	0	4	5
Mitogen-activated protein kinase 1	0	3	4	7
Ephrin type-A receptor 2	0	1	4	5
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	0	4	4
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	4	4
Phosphatidylethanolamine-binding protein 1	0	0	3	3
Wee1-like protein kinase	0	0	4	4
Heme oxygenase 2	0	0	4	4
Tyrosine-protein kinase receptor UFO	0	1	2	3
Mitogen-activated protein kinase 4	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	4	4
DnaJ homolog subfamily A member 1	0	0	4	4
RAC-alpha serine/threonine-protein kinase	0	2	4	6
RAC-beta serine/threonine-protein kinase	0	0	4	4
G protein-coupled receptor kinase 4	0	0	2	2
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	4	4
Myosin-10	0	0	3	3
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	2	2	4
Vascular endothelial growth factor receptor 2	0	6	3	10
Dual specificity mitogen-activated protein kinase kinase 2	0	1	4	5
Bone morphogenetic protein receptor type-1A	0	0	4	4
Activin receptor type-1B	0	0	4	4
TGF-beta receptor type-1	0	0	4	4
Serine/threonine-protein kinase receptor R3	0	0	2	2
TGF-beta receptor type-2	0	0	3	3
Electron transfer flavoprotein subunit beta	0	0	4	4
Tyrosine-protein kinase CSK	0	0	4	4
Glycine--tRNA ligase	0	0	4	4
Protein kinase C iota type	0	3	4	7
Exosome RNA helicase MTR4	0	0	4	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	2	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	2	2	4
Serine/threonine-protein kinase mTOR	0	5	2	7
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase Tec	0	0	4	4
Tyrosine-protein kinase TXK	0	0	2	2
Tyrosine-protein kinase ABL2	0	1	4	5
Tyrosine-protein kinase FRK	0	0	4	4
Tyrosine-protein kinase ZAP-70	0	0	2	2
26S proteasome regulatory subunit 6B	0	2	4	6
Mitogen-activated protein kinase 8	0	0	6	6
Mitogen-activated protein kinase 9	0	0	6	6
Dual specificity mitogen-activated protein kinase kinase 4	0	0	4	4
Dual specificity mitogen-activated protein kinase kinase 3	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	3	3
Casein kinase I isoform alpha	0	1	4	5
Casein kinase I isoform delta	0	1	4	5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	5	2	7
MAP kinase-activated protein kinase 2	0	0	4	4
Cyclin-dependent kinase 8	0	1	2	3
Elongation factor Tu, mitochondrial	0	0	4	4
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	4	4
Casein kinase I isoform epsilon	0	1	4	5
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	4	4
Dual specificity protein kinase CLK1	0	1	4	5
Dual specificity protein kinase CLK2	0	0	4	4
Dual specificity protein kinase CLK3	0	0	2	2
Cyclin-dependent kinase 7	0	1	4	5
Cyclin-dependent kinase 9	0	1	4	5
Ras-related protein Rab-27A	0	0	3	3
Tyrosine-protein kinase Blk	0	0	2	2
Interleukin-1 receptor-associated kinase 1	0	0	4	4
Ribosomal protein S6 kinase alpha-3	0	0	4	4
Cytoplasmic tyrosine-protein kinase BMX	0	0	2	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek2	0	1	4	5
Serine/threonine-protein kinase Nek3	0	0	4	4
Serine/threonine-protein kinase Nek4	0	0	2	2
Tyrosine-protein kinase JAK3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	4	4
Serine/threonine-protein kinase PLK1	0	2	3	5
Dipeptidyl peptidase 1	0	1	0	1
LIM domain kinase 1	0	0	4	4
LIM domain kinase 2	0	0	4	4
Tyrosine--tRNA ligase, cytoplasmic	0	0	4	4
5'-AMP-activated protein kinase subunit gamma-1	0	0	4	5
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	3
Ephrin type-B receptor 3	0	0	4	4
Ephrin type-A receptor 5	0	0	4	4
Ephrin type-B receptor 4	0	1	4	5
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	4	4
Adenylate kinase 2, mitochondrial	0	0	4	4
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Ras-related protein Rab-10	0	0	4	4
Cell division control protein 2 homolog	0	0	2	2
Actin-related protein 3	0	0	4	4
Actin-related protein 2	0	0	4	4
Calcium-dependent protein kinase 1	0	0	2	2
GTP-binding nuclear protein Ran	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase-like 1	0	0	2	2
Cyclin-dependent kinase 16	0	0	4	4
Cyclin-dependent kinase 17	0	0	3	3
Protein kinase C epsilon type	0	3	2	5
Dual specificity mitogen-activated protein kinase kinase 1	0	3	4	7
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
DNA topoisomerase 2-beta	0	0	4	4
Protein kinase C theta type	0	3	4	7
Activin receptor type-1	0	0	4	4
Macrophage-stimulating protein receptor	0	0	4	4
Focal adhesion kinase 1	0	1	4	5
Protein kinase C zeta type	0	3	2	5
Protein kinase C delta type	0	3	4	7
Tyrosine-protein kinase BTK	0	0	4	4
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	2
Activated CDC42 kinase 1	0	0	4	4
Epithelial discoidin domain-containing receptor 1	0	0	4	4
Tyrosine-protein kinase ITK/TSK	0	0	2	2
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	4	4
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	1	3	4
Serine/threonine-protein kinase 4	0	0	4	4
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	4	5
Serine/threonine-protein kinase PAK 1	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 5	0	0	4	4
Mitogen-activated protein kinase 7	0	0	4	4
Serine/threonine-protein kinase PAK 2	0	0	4	4
Serine/threonine-protein kinase 3	0	1	4	5
Mitogen-activated protein kinase kinase kinase 1	0	0	4	4
cGMP-dependent protein kinase 2	0	0	2	2
Integrin-linked protein kinase	0	0	3	3
Rho-associated protein kinase 1	0	0	4	4
Non-receptor tyrosine-protein kinase TNK1	0	0	4	4
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	4	4
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	2	4	6
Activin receptor type-2B	0	0	3	3
Bone morphogenetic protein receptor type-2	0	0	4	4
Protein-tyrosine kinase 6	0	0	4	4
cGMP-dependent protein kinase 1	0	0	4	4
Cyclin-dependent kinase 13	0	0	4	4
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	4	4
Protein-tyrosine kinase 2-beta	0	0	4	4
Maternal embryonic leucine zipper kinase	0	0	4	4
Chromodomain-helicase-DNA-binding protein 4	0	0	4	4
Peroxisomal acyl-coenzyme A oxidase 1	0	0	4	4
Serine/threonine-protein kinase D1	0	3	2	5
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	1	2	3
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	3	3
Delta(24)-sterol reductase	0	0	4	4
Ribosomal protein S6 kinase alpha-1	0	0	4	4
Dual specificity testis-specific protein kinase 1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	4	4
Serine/threonine-protein kinase STK11	0	0	4	4
Rhodopsin kinase GRK1	0	1	2	3
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	1	4	5
Serine/threonine-protein kinase N2	0	0	4	4
Calcium/calmodulin-dependent protein kinase type IV	0	0	3	3
Mitogen-activated protein kinase kinase kinase 11	0	0	4	4
BDNF/NT-3 growth factors receptor	0	0	2	2
MAP kinase-activated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Discoidin domain-containing receptor 2	0	1	4	5
AP2-associated protein kinase 1	0	0	4	4
Myosin light chain kinase 3	0	0	4	4
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	4	4
Serine/threonine-protein kinase TNNI3K	0	1	2	3
Rab-like protein 3	0	0	3	3
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	4	4
Serine/threonine-protein kinase MRCK gamma	0	0	4	4
Acyl-CoA dehydrogenase family member 10	0	0	4	4
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	4	4
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Uncharacterized protein FLJ45252	0	0	4	4
Acyl-CoA dehydrogenase family member 11	0	0	4	4
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	3	3
Serine/threonine-protein kinase MARK2	0	0	4	4
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	4	4
STE20-related kinase adapter protein alpha	0	0	4	4
Myosin-14	0	0	4	4
AarF domain-containing protein kinase 1	0	0	4	4
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	1	2	3
ATP-dependent RNA helicase DDX42	0	0	2	2
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	1	2	3
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	4	4
Cyclin-dependent kinase-like 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	4	4
Serine/threonine-protein kinase BRSK2	0	1	2	3
Serine/threonine-protein kinase NIM1	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Serine/threonine-protein kinase ULK2	0	0	2	2
Misshapen-like kinase 1	0	0	3	3
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	1	2	3
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	3	3
Mitogen-activated protein kinase 15	0	0	4	4
Serine/threonine-protein kinase Nek9	0	0	4	4
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	3	3
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	1	2	3
Cyclin-dependent kinase-like 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	3	3
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
MAP/microtubule affinity-regulating kinase 4	0	0	3	3
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	4	4
Cyclin-dependent kinase 15	0	0	2	2
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	4	4
EKC/KEOPS complex subunit TP53RK	0	0	4	4
SRSF protein kinase 1	0	0	2	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	4	4
Mitogen-activated protein kinase kinase kinase 5	0	0	4	4
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	4	4
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	4	4
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	1	2	3
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	1	2	3
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase 33	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	4	4
Serine/threonine-protein kinase D2	0	0	4	4
Serine/threonine-protein kinase DCLK3	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	4	4
Serine/threonine-protein kinase SIK2	0	0	4	4
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase TAO3	0	0	4	4
Homeodomain-interacting protein kinase 2	0	1	2	3
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	1	2	3
Serine/threonine-protein kinase PLK3	0	1	2	3
dCTP pyrophosphatase 1	0	0	4	4
Dual specificity protein kinase CLK4	0	0	4	4
Serine/threonine-protein kinase Nek6	0	1	2	3
Casein kinase I isoform gamma-1	0	0	4	4
Serine/threonine-protein kinase PAK 6	0	0	2	2
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	4	4
BMP-2-inducible protein kinase	0	0	4	4
Obg-like ATPase 1	0	0	4	4
Midasin	0	0	4	4
Interleukin-1 receptor-associated kinase 4	0	0	4	4
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	1	4	5
Cyclin-dependent kinase 12	0	0	4	4
Serine/threonine-protein kinase PLK2	0	1	2	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	3	3
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase PAK 5	0	0	2	2
Serine/threonine-protein kinase 26	0	0	4	4
eIF-2-alpha kinase GCN2	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	3	3
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	4	5
Serine/threonine-protein kinase TBK1	0	0	4	4
Septin-9	0	0	4	4
Death-associated protein kinase 2	0	0	2	2
Ribosomal protein S6 kinase alpha-6	0	0	4	4
TRAF2 and NCK-interacting protein kinase	0	0	4	4
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	4	4
Long-chain-fatty-acid--CoA ligase 5	0	0	3	3
ALK tyrosine kinase receptor	0	2	2	4
SRSF protein kinase 3	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	4	4
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	1	2	3
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	4	4
Serine/threonine-protein kinase 38-like	0	0	3	3
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 2	0	0	4	4
Thyroid hormone receptor-associated protein 3	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	2	3	5
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	4	4
Receptor-interacting serine/threonine-protein kinase 3	0	1	4	5
Serine/threonine-protein kinase MRCK beta	0	0	4	4
Interleukin-1 receptor-associated kinase 3	0	0	4	4
Serine/threonine-protein kinase 24	0	0	2	2
Casein kinase I isoform gamma-3	0	0	4	4
Mitogen-activated protein kinase kinase kinase 4	0	0	4	4
Transporter	0	7	0	7
caspase-1 isoform alpha precursor	3	0	0	3
Caspase-7	4	0	0	4
Metabotropic glutamate receptor 2	0	1	2	3
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	2	0	3
26S proteasome non-ATPase regulatory subunit 11	0	2	0	2
26S proteasome non-ATPase regulatory subunit 12	0	2	0	2
26S proteasome non-ATPase regulatory subunit 14	0	2	0	2
Proteasome subunit alpha type-7	0	2	0	3
26S proteasome non-ATPase regulatory subunit 3	0	2	0	2
Carbonic anhydrase 12	0	10	0	17
Prothrombin	0	2	2	4
Chymotrypsinogen A	0	3	0	3
Carbonic anhydrase 3	0	8	0	13
Cathepsin B	0	2	0	2
Cathepsin G	0	3	0	3
Lysosomal protective protein	0	2	0	2
Chymotrypsinogen B	0	2	0	2
26S proteasome regulatory subunit 6A	0	2	0	2
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	2	0	4
Carbonic anhydrase 6	0	9	0	15
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	2	0	3
Proteasome subunit alpha type-2	0	2	0	3
Proteasome subunit alpha type-3	0	2	0	3
Proteasome subunit alpha type-4	0	2	0	3
Proteasome subunit beta type-8	0	2	0	3
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	2	0	3
Proteasome subunit alpha type-5	0	2	0	3
Proteasome subunit beta type-4	0	2	0	3
Proteasome subunit beta type-6	0	2	0	3
Carbonic anhydrase 5A, mitochondrial	0	8	1	15
26S proteasome regulatory subunit 7	0	2	0	2
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	2	0	3
Carbonic anhydrase 7	0	10	0	16
26S proteasome non-ATPase regulatory subunit 8	0	2	0	2
Proteasome subunit beta type-3	0	2	0	3
Proteasome subunit beta type-2	0	2	0	4
26S proteasome non-ATPase regulatory subunit 7	0	2	0	2
26S proteasome non-ATPase regulatory subunit 4	0	2	0	2
26S proteasome complex subunit SEM1	0	2	0	2
Proteasome subunit alpha type-6	0	2	1	4
26S proteasome regulatory subunit 4	0	2	0	2
26S proteasome regulatory subunit 8	0	2	0	2
26S proteasome regulatory subunit 10B	0	2	0	2
Beta-carbonic anhydrase 1	0	4	0	4
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	2	0	2
26S proteasome non-ATPase regulatory subunit 6	0	2	0	2
Proteasomal ubiquitin receptor ADRM1	0	2	0	2
Carbonic anhydrase 9	0	12	1	20
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	5	0	7
NACHT, LRR and PYD domains-containing protein 3	0	3	0	3
Proteasome subunit alpha-type 8	0	2	0	3
Proteasome subunit beta type-7	0	2	0	3
26S proteasome non-ATPase regulatory subunit 1	0	2	0	2
Carbonic anhydrase 15	0	10	0	15
Carbonic anhydrase 14	0	8	0	14
26S proteasome non-ATPase regulatory subunit 13	0	2	0	2
Carbonic anhydrase 5B, mitochondrial	0	8	0	14
Alpha-2A adrenergic receptor	0	55	6	63
Delta-type opioid receptor	0	28	6	42
D(3) dopamine receptor	0	2	1	3
Genome polyprotein	0	2	1	3
ATP-dependent translocase ABCB1	0	4	0	4
Beta-1 adrenergic receptor	0	12	2	14
ATP-dependent translocase ABCB1	0	4	1	6
Alpha-synuclein	9	9	1	19
Nuclear hormone receptor family member daf-12	0	0	1	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	2	0	3
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	6	6	12
Potassium channel subfamily K member 9	0	1	0	1
Integrin alpha-5	0	1	0	1
Bile salt export pump	0	16	0	16
Beta-2 adrenergic receptor	0	8	0	9
Angiotensin-converting enzyme	0	1	0	1
Beta-1 adrenergic receptor	0	7	1	9
Beta-3 adrenergic receptor	0	6	0	6
Alpha-2A adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
Lysosomal alpha-glucosidase	0	2	0	2
Chain A, Nitrile Hydratase alpha subunit	0	1	0	1
Chain B, Nitrile Hydratase beta subunit	0	1	0	1
Lysine-specific demethylase 4E	0	2	0	2
Free fatty acid receptor 3	0	0	1	1
Methyl-accepting chemotaxis protein NahY	0	0	2	2
Eukaryotic translation initiation factor 5B	0	0	1	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	2	0	2
UMP-CMP kinase	0	0	2	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	3	3
Serine-protein kinase ATM	0	3	0	3
Serine/threonine-protein kinase ATR	0	3	3	6
Structural maintenance of chromosomes protein 1A	0	0	3	3
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	3	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
Glycogen phosphorylase, muscle form	0	3	0	3
Renin	0	3	2	5
Cholinesterase	0	15	0	15
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	8	0	8
Vasopressin V2 receptor	0	0	0	2
Adenosine receptor A2a	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Adenylate cyclase type 1	0	1	0	3
Chitotriosidase-1	0	2	0	2
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	2	3	5
Endochitinase B1	0	2	0	2
Phosphodiesterase	0	2	0	2
Acetylcholinesterase	0	18	0	19
L-lactate dehydrogenase A chain	0	2	0	2
Cytochrome P450 2C11	0	2	0	2
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Cytochrome P450 3A5	0	3	0	3
Cytochrome P450 3A7	0	2	0	2
Caspase-1	0	2	1	3
Peroxisome proliferator-activated receptor gamma	0	4	8	12
Cholinesterase	0	14	1	16
N-acylethanolamine-hydrolyzing acid amidase	0	1	0	1
Heat sensitive channel TRPV3	0	1	1	2
Sigma intracellular receptor 2	0	3	0	3
Transient receptor potential cation channel subfamily A member 1	0	1	2	3
Transient receptor potential cation channel subfamily M member 8	0	1	1	2
Transient receptor potential cation channel subfamily V member 4	0	2	2	4
G-protein coupled receptor 55	0	1	3	4
Diacylglycerol lipase-alpha	0	1	0	1
transient receptor potential cation channel subfamily V member 1	4	0	0	4
Transient receptor potential cation channel subfamily V member 1	0	4	1	5
Lysine-specific histone demethylase 1A	0	5	0	6
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	8	0	8
Potassium voltage-gated channel subfamily A member 1	0	2	0	2
Vpr	4	0	0	4
Albumin	0	0	8	8
Major prion protein	0	0	5	5
Sodium channel protein type 1 subunit alpha	0	5	0	5
Sodium channel protein type 2 subunit alpha	0	7	0	7
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	7	0	9
Cytochrome P450 2J2	0	18	0	19
Sodium channel protein type 9 subunit alpha	0	8	0	8
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
Chain A, serum paraoxonase	0	1	0	1
Delta-type opioid receptor	0	25	4	33
Mu-type opioid receptor	0	29	5	38
Kappa-type opioid receptor	0	15	4	20
Proteasome subunit beta type-2	0	1	0	1
Proteasome subunit beta type-1	0	1	0	1
Glutathione S-transferase omega-1	0	2	0	2
histone-lysine N-methyltransferase 2A isoform 2 precursor	15	0	0	15
Toll-like receptor 4	0	1	0	1
Beta-2 adrenergic receptor	0	12	2	14
Beta-3 adrenergic receptor	0	15	2	17
Potassium channel subfamily K member 10	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	33	0	33
Chain A, Carbonic anhydrase II	0	1	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	4	0	4
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
Carbonic anhydrase	0	3	0	3
interferon gamma precursor	0	0	0	5
prostaglandin E2 receptor EP2 subtype	0	0	0	1
Prostaglandin E synthase	0	3	0	3
Cytochrome c oxidase subunit 1	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Procathepsin L	0	5	6	11
Quinolone resistance protein NorA	0	2	0	2
Calpain-2 catalytic subunit	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cruzipain	0	3	0	3
Sodium/hydrogen exchanger 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Bifunctional epoxide hydrolase 2	0	4	0	4
Prostaglandin G/H synthase 2	0	2	0	2
Carbonic anhydrase	0	8	0	13
Carbonic anhydrase	0	3	0	9
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 2	0	3	0	3
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase, alpha family	0	3	0	3
Carbonic anhydrase	0	2	0	8
Carbonic anhydrase	0	2	0	8
Carbonic anhydrase	0	3	0	9
Carbonic anhydrase	0	3	0	3
Sigma intracellular receptor 2	0	8	0	8
Delta carbonic anhydrase	0	3	0	3
Prostaglandin G/H synthase 1	0	2	0	2
Carbonic anhydrase	0	2	0	8
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Rap guanine nucleotide exchange factor 4	8	0	0	8
Caspase-2	0	0	1	1
DNA polymerase III, partial	5	0	0	5
hexokinase-4 isoform 1	4	0	0	4
polyunsaturated fatty acid lipoxygenase ALOX12	7	0	0	7
glucokinase regulatory protein	4	0	0	4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	6	0	6
Aromatic-L-amino-acid decarboxylase	0	1	0	1
Bcl-2-like protein 1	0	1	0	1
Single-stranded DNA cytosine deaminase	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	6	0	7
Gamma-aminobutyric acid receptor subunit beta-1	0	6	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	0	6	0	7
Gamma-aminobutyric acid receptor subunit alpha-3	0	6	0	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	6	0	7
Gamma-aminobutyric acid receptor subunit gamma-2	0	6	0	7
Cholecystokinin receptor type A	1	3	0	4
Gastrin/cholecystokinin type B receptor	1	2	1	4
1,3-beta-D-glucan synthase catalytic subunit	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 2	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	4	1	7
large T antigen	0	3	1	4
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	2	0	2
Spike glycoprotein	0	4	6	10
glucose-6-phosphate 1-dehydrogenase isoform b	0	2	0	2
Transmembrane protease serine 2	0	4	6	10
Dihydrofolate reductase	0	3	0	3
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	2	0	3
Spike glycoprotein	0	1	0	1
DNA ligase 1	0	1	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	2	2
Calcium-dependent protein kinase 1	0	0	1	1
DNA ligase A	0	1	0	1
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	4	6	10
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
NADPH oxidase 1	0	2	0	2
Snq2p	0	0	0	3
Adenylate cyclase type 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 2D	0	8	1	9
Glutamate receptor ionotropic, NMDA 3B	0	7	0	7
Voltage-dependent L-type calcium channel subunit alpha-1F	0	13	0	13
Albumin	0	3	10	14
Major prion protein	0	0	1	1
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	4	1	5
Polyunsaturated fatty acid lipoxygenase ALOX15	0	9	0	9
Sphingomyelin phosphodiesterase	0	2	0	2
Adenylate cyclase type 3	0	4	0	4
Histamine H2 receptor	0	24	4	28
Adenylate cyclase type 2	0	4	0	4
Adenylate cyclase type 4	0	4	0	4
Trypanothione reductase	0	4	0	4
Melanocortin receptor 4	0	4	0	4
Melanocortin receptor 5	0	8	0	8
Pleiotropic ABC efflux transporter of multiple drugs	0	3	0	6
Sodium channel protein type 1 subunit alpha	0	6	0	6
Adenylate cyclase type 8	0	4	0	4
Melanocortin receptor 3	0	4	0	4
Gastrin/cholecystokinin type B receptor	0	3	0	3
Calmodulin	0	1	2	3
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	13	0	13
Adenylate cyclase type 6	0	4	0	4
Adenylate cyclase type 5	0	4	0	4
Glutamate receptor ionotropic, NMDA 1	0	10	0	10
Aldehyde oxidase	0	4	0	4
Glutamate receptor ionotropic, NMDA 2A	0	10	1	11
Voltage-dependent L-type calcium channel subunit alpha-1S	0	13	0	13
Voltage-dependent L-type calcium channel subunit alpha-1C	0	15	0	15
Sodium channel protein type 5 subunit alpha	0	10	0	10
Glutamate receptor ionotropic, NMDA 2C	0	8	1	9
Adenylyl cyclase 7	0	4	0	4
Glutamate receptor ionotropic, NMDA 3A	0	7	0	7
Sodium channel protein type 2 subunit alpha	0	6	0	6
Sodium channel protein type 3 subunit alpha	0	6	0	6
Sodium channel protein type 11 subunit alpha	0	4	0	4
Sodium channel protein type 8 subunit alpha	0	4	0	4
Sodium channel protein type 10 subunit alpha	0	4	0	4
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
High affinity choline transporter 1	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain B, cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	4	0	4
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	7	0	7
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	9	0	9
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	5	0	5
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	5	0	5
Phosphodiesterase	0	1	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	2	0	2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Sodium-dependent noradrenaline transporter	0	4	0	4
Aldo-keto reductase family 1 member B1	0	6	0	6
Aromatase	0	1	0	1
Sodium-dependent serotonin transporter	0	4	0	4
Sodium-dependent dopamine transporter	0	6	0	6
Transporter	0	20	1	22
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	3	0	3
perilipin-1	0	3	0	3
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	3	0	3
Beta-lactamase	0	1	0	1
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	1	0	2
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	4	0	4
Alpha-ketoglutarate-dependent dioxygenase FTO	0	3	0	3
GALC protein	12	0	0	12
Peroxisome proliferator-activated receptor alpha	0	1	3	4
Peroxisome proliferator-activated receptor alpha	0	4	5	9
Beta-1 adrenergic receptor	0	2	2	5
Alpha-1B adrenergic receptor	0	0	2	2
Membrane primary amine oxidase	0	1	0	1
Alpha-1A adrenergic receptor	0	4	2	6
Alpha-2B adrenergic receptor	0	3	0	4
Alpha-2C adrenergic receptor	0	3	0	4
Alpha-2A adrenergic receptor	0	3	0	4
Nischarin	0	3	0	3
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
Endothelin receptor type B	0	1	0	1
Histamine H1 receptor	0	12	1	13
5-hydroxytryptamine receptor 2C	0	4	0	4
5-hydroxytryptamine receptor 2A	0	3	0	3
5-hydroxytryptamine receptor 5A	0	6	0	6
D(2) dopamine receptor	0	2	0	2
D(2) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 4	0	3	1	4
Cholecystokinin receptor type A	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	0	3
Histamine H4 receptor	0	5	4	9
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	1	2
Liver carboxylesterase 1	0	1	0	3
Lysosomal Pro-X carboxypeptidase	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
nonstructural protein 1	13	0	0	13
Sex hormone-binding globulin	0	0	5	5
Corticosteroid-binding globulin	0	4	0	4
Mineralocorticoid receptor	1	2	2	6
C-8 sterol isomerase	0	3	0	3
Solute carrier organic anion transporter family member 1A1	0	3	0	4
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	4	1	5
glycogen synthase kinase-3 alpha	0	0	0	1
Exportin-1	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	2	0	4
Amine oxidase [flavin-containing] B	0	8	0	9
Amine oxidase [flavin-containing] A	0	6	0	7
Acetylcholinesterase	0	7	0	7
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	2	0	2
Quinone oxidoreductase	0	0	0	1
Sorbitol dehydrogenase	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Zn finger protein	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Carbonic anhydrase 13	0	4	0	9
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	7	0	8
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
PINK1	3	0	0	3
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	1	0	1
huntingtin isoform 2	10	0	0	10
pyruvate kinase PKM isoform a	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
tumor susceptibility gene 101 protein	4	0	0	4
hypothetical protein SA1422	0	1	0	1
D-amino-acid oxidase	0	2	0	2
Phospholipase A2	0	2	0	2
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	1	0	1
Glutathione S-transferase P	0	2	0	2
60 kDa chaperonin	0	2	0	2
Microtubule-associated protein tau	0	1	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	4	0	4
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Heme oxygenase 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Lactoylglutathione lyase	0	6	0	6
Histone acetyltransferase p300	0	1	0	1
Sodium/bile acid cotransporter	0	1	1	2
Nuclear factor erythroid 2-related factor 2	0	0	1	2
Thioredoxin reductase 1, cytoplasmic	0	1	0	1
Thioredoxin reductase 3	0	1	0	1
Sortase A	0	1	0	1
CREB-binding protein	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	1	0	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	1	0	2
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
D-alanine--D-alanine ligase	0	1	0	1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	0	1	0	1
Acetylcholine receptor subunit beta	0	4	1	5
Acetylcholine receptor subunit gamma	0	4	1	5
Acetylcholine receptor subunit delta	0	4	3	7
Alpha-tocopherol transfer protein	0	0	1	1
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Glucose-6-phosphate 1-dehydrogenase	0	4	0	4
G-protein coupled bile acid receptor 1	0	1	2	3
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Solute carrier organic anion transporter family member 1A4	0	2	0	4
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Steryl-sulfatase	0	0	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	3
Solute carrier organic anion transporter family member 1A3	0	1	0	3
ATP-binding cassette sub-family C member 11	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
AAA family ATPase	0	0	0	1
Sterol O-acyltransferase 1	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	5	0	5
Histamine H3 receptor	0	1	1	2
Solute carrier family 22 member 4	0	1	0	1
Amine oxidase [flavin-containing] B	0	5	0	6
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	2	2
Trace amine-associated receptor 1	0	0	3	3
Trace amine-associated receptor 1	0	0	3	3
Cytochrome P450 2D1	0	3	0	3
Cytochrome P450 2D26	0	3	0	3
Cytochrome P450 2D3	0	3	0	3
Taste receptor type 2 member 46	0	0	1	1
Cytochrome P450 2D4	0	3	0	3
Gamma-aminobutyric acid	0	2	2	4
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit delta	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	2	4
Translocator protein	0	1	0	1
Translocator protein	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	2	5
Gamma-aminobutyric acid receptor subunit beta-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	2	4
Gamma-aminobutyric acid receptor subunit pi	0	2	2	4
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	2	4
Gamma-aminobutyric acid receptor subunit theta	0	2	2	4
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-5	0	1	2	3
Neuronal acetylcholine receptor subunit beta-4	0	3	0	3
Neuronal acetylcholine receptor subunit beta-2	0	3	1	4
runt-related transcription factor 1 isoform AML1b	3	0	0	3
core-binding factor subunit beta isoform 2	3	0	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	7	0	7
90-kda heat shock protein beta HSP90 beta, partial	0	2	0	2
isocitrate dehydrogenase 1, partial	2	0	0	2
LANA	0	0	0	1
serine-protein kinase ATM isoform a	3	0	0	3
eyes absent homolog 2 isoform a	2	0	0	2
heat shock protein HSP 90-alpha isoform 2	0	2	0	4
kelch-like ECH-associated protein 1	0	0	0	2
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	0	1	0	1
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	0	1	0	1
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	2	0	2
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma	0	1	0	1
Exopolyphosphatase PRUNE1	0	1	0	1
Phosphodiesterase	0	1	0	1
LacZ protein (plasmid)	0	0	1	1
type-1 angiotensin II receptor	0	1	0	1
polypyrimidine tract-binding protein 1 isoform a	1	0	0	1
apelin receptor	0	1	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	4	5
Carbamate kinase	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
C-X-C chemokine receptor type 2	0	2	0	2
Protein-lysine 6-oxidase	0	1	0	1
Lysine-specific demethylase 5A	0	1	0	1
C-C chemokine receptor type 2	0	2	0	2
C-C chemokine receptor type 4	0	3	0	3
C-C chemokine receptor type 5	0	2	0	2
Gasdermin-D	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	1	0	1
Monoglyceride lipase	0	3	0	3
Gasdermin-D	0	1	0	1
Histone-lysine N-methyltransferase EHMT1	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
heat shock protein 90, putative	0	0	0	2
hypothetical protein CAALFM_CR05890CA	0	0	0	1
H3 histone acetyltransferase	0	0	0	1
Acetylcholinesterase	0	5	0	5
Amine oxidase [flavin-containing] A	0	4	0	4
Acetylcholinesterase	0	6	0	6
Cholinesterase	0	4	0	4
Acetylcholine receptor subunit epsilon	0	1	2	3
Acyl-CoA:cholesterol acyltransferase	0	2	0	2
Carboxylic ester hydrolase	0	7	0	7
Alpha-1A adrenergic receptor	0	2	1	3
Interstitial collagenase	0	4	1	5
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Glycine receptor subunit alpha-1	0	0	3	3
N-arachidonyl glycine receptor	0	1	1	2
Lysophosphatidylserine lipase ABHD12	0	1	0	1
Monoacylglycerol lipase ABHD6	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	4	4
Chain A, Protein (peroxisome Proliferator Activated Receptor (ppar-delta))	0	1	0	1
Trypsin	0	1	0	2
Coagulation factor VII	0	3	0	3
Retinoic acid receptor RXR-alpha	0	3	6	9
Oxoeicosanoid receptor 1	0	1	0	1
Sodium/glucose cotransporter 1	0	0	1	1
Sodium/glucose cotransporter 2	0	1	1	2
Opioid receptor, delta 1b	0	2	0	2
Opioid receptor homologue	0	2	0	2
Proenkephalin-B	0	0	1	1
Kappa-type opioid receptor	0	10	4	18
Mu-type opioid receptor	0	10	3	19
Mu-type opioid receptor	0	2	0	2
Nociceptin receptor	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	5
Pantothenate synthetase	0	2	0	2
Cytochrome P450 2B1	0	2	0	2
Glycine receptor subunit alpha-1	0	6	0	6
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Glycine receptor subunit alpha-3	0	6	0	6
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
streptokinase A precursor	0	0	6	6
Estrogen receptor	0	0	4	5
Estrogen receptor beta	0	0	4	5
Transient receptor potential cation channel subfamily M member 8	0	1	2	5
Ubiquitin carboxyl-terminal hydrolase isozyme L3	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase isozyme L1	0	1	0	1
Fatty acid-binding protein, liver	0	1	0	1
Peroxisome proliferator-activated receptor alpha	0	0	2	2
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	1	2
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	1	2
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	1	2
Prostaglandin D2 receptor 2	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	5
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	3	0	3
30S ribosomal protein S7	0	3	0	3
50S ribosomal protein L15	0	3	0	3
50S ribosomal protein L10	0	3	0	3
50S ribosomal protein L11	0	3	0	3
50S ribosomal protein L7/L12	0	3	0	3
50S ribosomal protein L19	0	3	0	3
50S ribosomal protein L1	0	3	0	3
50S ribosomal protein L20	0	3	0	3
50S ribosomal protein L27	0	3	0	3
50S ribosomal protein L28	0	3	0	3
50S ribosomal protein L29	0	3	0	3
50S ribosomal protein L31	0	3	0	3
50S ribosomal protein L31 type B	0	3	0	3
50S ribosomal protein L32	0	3	0	3
50S ribosomal protein L33	0	3	0	3
50S ribosomal protein L34	0	3	0	3
50S ribosomal protein L35	0	3	0	3
50S ribosomal protein L36	0	3	0	3
30S ribosomal protein S10	0	3	0	3
30S ribosomal protein S11	0	3	0	3
30S ribosomal protein S12	0	3	0	3
30S ribosomal protein S13	0	3	0	3
30S ribosomal protein S16	0	3	0	3
30S ribosomal protein S18	0	3	0	3
30S ribosomal protein S19	0	3	0	3
30S ribosomal protein S20	0	3	0	3
30S ribosomal protein S2	0	3	0	3
30S ribosomal protein S3	0	3	0	3
30S ribosomal protein S4	0	3	0	3
30S ribosomal protein S5	0	3	0	3
30S ribosomal protein S8	0	3	0	3
30S ribosomal protein S9	0	3	0	3
50S ribosomal protein L13	0	3	0	3
50S ribosomal protein L14	0	3	0	3
50S ribosomal protein L16	0	3	0	3
50S ribosomal protein L23	0	3	0	3
30S ribosomal protein S15	0	3	0	3
50S ribosomal protein L17	0	3	0	3
50S ribosomal protein L21	0	3	0	3
50S ribosomal protein L30	0	3	0	3
50S ribosomal protein L6	0	3	0	3
30S ribosomal protein S14	0	3	0	3
30S ribosomal protein S17	0	3	0	3
30S ribosomal protein S1	0	3	0	3
50S ribosomal protein L18	0	3	0	3
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	3	0	3
50S ribosomal protein L3	0	3	0	3
50S ribosomal protein L24	0	3	0	3
50S ribosomal protein L4	0	3	0	3
50S ribosomal protein L22	0	3	0	3
50S ribosomal protein L5	0	3	0	3
30S ribosomal protein S21	0	3	0	3
50S ribosomal protein L25	0	3	0	3
50S ribosomal protein L36 2	0	3	0	3
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	2	0	2
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
Prolyl endopeptidase	0	2	0	2
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	5	0	5
Gamma-aminobutyric acid receptor subunit rho-1	0	0	4	4
Gamma-aminobutyric acid receptor subunit rho-2	0	0	2	2
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	5	0	5
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Sodium- and chloride-dependent GABA transporter 2	0	4	0	4
Sodium- and chloride-dependent GABA transporter 3	0	4	0	4
Sodium- and chloride-dependent betaine transporter	0	4	0	4
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
Sterol O-acyltransferase 1	0	0	1	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Glucagon-like peptide 1 receptor	0	0	1	1
Glucagon-like peptide 1 receptor	0	3	3	6
Glucagon receptor	0	0	1	1
Glucagon receptor	0	0	1	1
Asialoglycoprotein receptor 1	0	1	1	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
Glutathione reductase, mitochondrial	0	5	0	5
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	6	1	8
Metabotropic glutamate receptor 3	0	1	1	2
Metabotropic glutamate receptor 4	0	2	1	3
Metabotropic glutamate receptor 6	0	1	1	2
Metabotropic glutamate receptor 7	0	1	1	2
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Glutamate receptor ionotropic, kainate 2	0	6	1	8
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	6	0	7
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	2	1	3
Glutamate receptor ionotropic, kainate 4	0	6	0	7
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	6	0	7
Glutamate racemase	0	0	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
ATP-binding cassette sub-family C member 9	0	1	0	1
ATP synthase subunit beta, mitochondrial	0	1	0	1
ATP synthase subunit delta, mitochondrial	0	1	0	1
ATP synthase subunit gamma, mitochondrial	0	1	0	1
ATP synthase subunit epsilon, mitochondrial	0	1	0	1
Cholesteryl ester transfer protein	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
ATP-binding cassette sub-family C member 8	0	1	0	1
ATP-sensitive inward rectifier potassium channel 11	0	1	0	1
Solute carrier family 22 member 7	0	1	0	2
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Sodium- and chloride-dependent glycine transporter 1	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	8	0	9
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	1	2	3
Sodium- and chloride-dependent glycine transporter 2	0	2	0	2
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Chain A, 3-phosphoshikimate 1-carboxyvinyltransferase	0	1	0	1
Glutamine synthetase	0	1	0	1
Cytochrome P450 71B1	0	1	0	2
Glutamine synthetase	0	1	0	1
2-dehydro-3-deoxyphosphooctonate aldolase	0	1	0	1
POU domain, class 2, transcription factor 1	0	0	0	1
Chain A, Probable hydrogenase nickel incorporation protein hypB	0	0	1	1
Chain B, Probable hydrogenase nickel incorporation protein hypB	0	0	1	1
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Chain A, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR	0	1	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	1	0	2
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	0	1	1
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
5-hydroxytryptamine receptor 2A	0	2	1	3
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	2	0	2
Protease	0	5	0	5
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
DNA repair and recombination protein RAD54-like isoform 1	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Tryptophan 2,3-dioxygenase	0	3	0	4
Chain A, Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Glycogen synthase kinase-3 beta	0	1	0	1
CDC-like kinase 1, isoform CRA_c	0	0	0	1
[Tau protein] kinase	0	1	0	1
dual specificity protein kinase CLK4	1	0	0	1
Dual specificity protein kinase CLK2	0	1	0	1
Dual specificity protein kinase CLK3	0	1	0	1
Dual specificity protein kinase CLK4	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 3	0	1	0	1
Cyclin-T1	0	1	0	1
Protein kinase C gamma type	0	3	0	3
Dual specificity protein kinase CLK1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
5-hydroxytryptamine receptor 1B	0	6	1	7
Neuromedin-B receptor	0	1	0	1
Cyclin-H	0	1	0	1
Mitogen-activated protein kinase 1	0	1	0	1
Cyclin-A1	0	2	0	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Serine/threonine-protein kinase haspin	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 4	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
Plasma kallikrein	0	0	0	5
Macrophage migration inhibitory factor	0	3	0	3
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
ClpP	3	0	0	3
Solute carrier family 22 member 8	0	0	0	1
Protein cereblon	0	6	1	9
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	2
Envelope glycoprotein	0	0	3	3
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Indoleamine 2,3-dioxygenase 1	0	3	1	5
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	2	0	3
DNA gyrase subunit B	0	2	0	3
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	3	0	4
DNA gyrase subunit A	0	3	0	4
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Endonuclease 8-like 1	0	1	0	1
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
tyrosine-protein kinase Yes	6	0	0	6
Monoglyceride lipase	0	1	0	1
Monoglyceride lipase	0	1	0	1
Synaptic vesicular amine transporter	0	2	0	2
G protein-coupled receptor GPR35	0	0	1	1
Vesicular glutamate transporter 3	0	1	0	1
G-protein coupled receptor 35	0	4	3	7
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	3
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
Leukotriene C4 synthase	0	1	0	1
Macrophage-expressed gene 1 protein	0	1	0	1
Leukotriene C4 synthase	0	0	0	1
Prostaglandin E synthase 2	0	1	0	1
Cereblon isoform 4	0	1	0	1
Bromodomain-containing protein 4	0	1	0	1
DNA-binding protein Ikaros	0	0	1	3
DNA damage-binding protein 1	0	1	0	1
Zinc finger protein Aiolos	0	0	1	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	5	0	5
Intestinal-type alkaline phosphatase	0	4	0	4
Phospholipase A-2-activating protein	0	4	0	4
WRN	3	0	0	3
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
SLC16A10 protein	0	0	0	4
Monocarboxylate transporter 10	0	0	0	4
Progesterone receptor	0	3	2	7
Delta-aminolevulinic acid dehydratase	0	2	0	2
inositol monophosphatase 1	1	0	0	1
5-hydroxytryptamine receptor 2C	0	0	1	1
Type-1 angiotensin II receptor	0	1	0	1
histidine kinase	0	1	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	2
P53	1	0	0	1
galactokinase	2	0	0	2
Chemotaxis protein CheA	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Stromelysin-1	0	4	1	5
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	2	0	2
Alpha-amylase 1A	0	2	0	2
Fatty acid synthase	0	1	0	1
Matrix metalloproteinase-9	0	3	0	3
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Cytosol aminopeptidase	0	2	0	2
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Macrophage metalloelastase	0	2	0	2
Collagenase 3	0	4	0	4
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	2	0	2
Fatty acid synthase	0	2	0	2
Protein polybromo-1	0	0	1	1
Histone-lysine N-methyltransferase SETD7	0	1	0	1
3-oxoacyl-acyl-carrier protein reductase	0	3	0	3
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	3	0	3
DNA topoisomerase 1	0	1	0	1
M1-family alanyl aminopeptidase	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
5-hydroxytryptamine receptor 1E	0	2	0	2
Sodium-dependent dopamine transporter	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Cysteinyl leukotriene receptor 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Cytochrome P450 1A2	0	1	1	5
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1A	0	2	1	3
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1B	0	2	1	3
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Secreted chorismate mutase	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	3	3
Dihydrofolate reductase	0	5	0	5
galanin receptor type 3	0	2	0	2
Aldehyde oxidase 1	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	1	0	2
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Cytochrome P450 2A13	0	3	2	5
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Chain A, PROGESTERONE RECEPTOR	0	1	0	1
Glucocorticoid receptor	0	1	0	1
Tegument protein VP16	0	0	1	1
Glucocorticoid receptor	0	1	1	3
Glucocorticoid receptor	0	1	0	1
Thyroid hormone receptor alpha	0	1	1	2
Thyroid hormone receptor beta	0	1	1	2
Progesterone receptor	0	0	1	1
Glucocorticoid receptor	0	1	0	1
Acyl-CoA desaturase 1	0	2	0	2
Histidine decarboxylase	0	0	3	3
Proteinase-activated receptor 1	0	1	1	2
Mu-type opioid receptor	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0	0	0	1
Peroxisome proliferator-activated receptor delta	0	0	2	2
Acid ceramidase	0	2	0	2
Glucose-dependent insulinotropic receptor	0	0	1	1
Glucose-dependent insulinotropic receptor	0	0	1	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Nociceptin receptor	0	2	1	3
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Neurotensin receptor type 1	0	0	1	1
Neurotensin receptor type 2	0	1	1	3
Myelin basic protein	0	0	1	1
Neurotensin receptor type 1	0	1	1	2
Neurotensin receptor type 1	0	2	2	5
Neurotensin receptor type 2	0	2	1	3
Sortilin	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	2	0	2
NAD-dependent protein deacetylase sirtuin-1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	3	0	4
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	2	0	2
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	3	0	3
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP14	0	1	1	2
Protein mono-ADP-ribosyltransferase PARP10	0	1	1	2
Protein mono-ADP-ribosyltransferase PARP16	0	0	1	1
Protein mono-ADP-ribosyltransferase PARP12	0	1	1	2
Protein mono-ADP-ribosyltransferase PARP11	0	0	1	1
Poly [ADP-ribose] polymerase 2	0	2	2	6
Protein mono-ADP-ribosyltransferase PARP4	0	1	1	2
Protein mono-ADP-ribosyltransferase PARP3	0	1	1	4
Sodium/iodide cotransporter	0	1	0	1
Lysine-specific demethylase 4C	0	2	0	2
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
STE24	0	0	0	1
CAAX prenyl protease	0	0	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
DNA repair protein RAD52 homolog	0	1	0	1
MBT domain-containing protein 1	0	1	0	1
Lethal(3)malignant brain tumor-like protein 4	0	1	0	1
Lethal(3)malignant brain tumor-like protein 3	0	1	0	1
Lethal(3)malignant brain tumor-like protein 1	0	1	0	1
Oxytocin receptor	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	2	0	2
Substance-P receptor	0	5	1	6
Rhodopsin kinase GRK1	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
G protein-coupled receptor kinase 5	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	0	1
Gastrin/cholecystokinin type B receptor	0	1	1	2
Arylacetamide deacetylase	0	1	0	3
Solute carrier family 22 member 6	0	2	0	3
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Chain A, PROTEIN (CATECHOL OXIDASE)	0	1	0	1
Tyrosinase	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Taste receptor type 2 member 38	0	0	2	4
Acetylcholinesterase	0	1	0	1
Retinoic acid receptor RXR-beta	0	2	3	5
Retinoic acid receptor RXR-gamma	0	2	3	5
Chloride channel isoform 1	0	0	1	1
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
Pirin	0	1	0	1
GTPase KRas	0	1	0	1
Serine/threonine-protein kinase B-raf	0	2	0	2
G protein-coupled receptor kinase 6	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Heat shock factor protein 1	0	2	0	2
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Cyclin-dependent kinase 10	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	2	2
Beta-casein	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	2	0	2
Alpha-mannosidase 2C1	0	0	1	1
Bromodomain-containing protein 2	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
Type-1 angiotensin II receptor	0	1	0	1
Cholesterol 24-hydroxylase	0	1	0	1
Endothelin-1 receptor	0	1	1	2
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Thyroid peroxidase	0	1	0	1
dual specificity protein phosphatase 3	0	1	0	1
low molecular weight phosphotyrosine protein phosphatase isoform c	0	1	0	1
tyrosine-protein phosphatase non-receptor type 22 isoform 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Beta-hexosaminidase subunit alpha	0	1	0	2
Beta-hexosaminidase subunit beta	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Substance-K receptor	0	2	1	3
Dihydrofolate reductase	0	1	0	1
Low molecular weight phosphotyrosine protein phosphatase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Multidrug and toxin extrusion protein 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	1	0	2
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	2	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
hexokinase	0	1	0	1
Maltase-glucoamylase, intestinal	0	1	0	1
B2 bradykinin receptor	0	1	0	1
Arginase	0	1	0	1
Pancreatic triacylglycerol lipase	0	1	0	1
Prothrombin	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Protein E6	0	1	0	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	1	0	1
Epoxide hydrolase 1	0	1	0	1
Trypsin-1	0	1	0	1
Trypsin-2	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Lysosomal alpha-glucosidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
G1/S-specific cyclin-D1	0	2	0	2
C-X-C chemokine receptor type 1	0	1	0	1
Trypsin-3	0	1	0	1
Glutathione reductase	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Oligo-1,6-glucosidase IMA1	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
ELAV-like protein 3	0	1	0	1
ELAV-like protein 1	0	1	0	1
Probable maltase-glucoamylase 2	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Chymotrypsin-C	0	1	0	1
Dipeptidyl peptidase 4	0	0	1	1
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	3
Toll-like receptor 7	0	0	1	3
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Acetylcholine receptor subunit epsilon	0	1	0	1
Cholinesterase	0	1	0	1
Sphingosine kinase 2	0	2	0	2
Sphingosine kinase 1	0	1	0	1
Taste receptor type 2 member 31	0	0	1	1
RmtA	0	1	0	1
Protein arginine N-methyltransferase 1	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Estrogen receptor	0	1	0	2
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	3
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
LMP1 [Human herpesvirus 4]	0	0	0	1
Orexin receptor type 1	0	2	0	4
Orexin receptor type 2	0	2	0	3
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 3	0	1	0	1
Adenylate cyclase type 9	0	1	0	1
D(1) dopamine receptor	0	1	0	1
Adenylate cyclase type 8	0	1	0	1
Adenylate cyclase type 7	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
C-X-C chemokine receptor type 3	0	2	0	2
Amine oxidase [flavin-containing] B	0	0	0	1
Transcriptional activator protein LuxR	0	2	0	2
photoreceptor-specific nuclear receptor	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Eyes absent homolog 2	0	1	0	1
Carbonic anhydrase	0	1	0	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
melanocortin receptor 4	0	1	1	2
Tyrosine-protein kinase ABL1	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-C	0	1	1	2
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
Tubulin alpha-1A chain	0	0	1	1
Protein delta homolog 1	0	0	1	1
Vascular endothelial growth factor receptor 2	0	1	0	1
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
Cathepsin B	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Proto-oncogene tyrosine-protein kinase LCK	0	1	0	1
Neuromedin-K receptor	0	0	1	1
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Chain A, Protein (aspartate Aminotransferase)	0	0	1	1
Chain A, Aspartate Aminotransferase	0	0	1	1
NADP-dependent malic enzyme, mitochondrial	0	0	0	1
Solute carrier family 13 member 3	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Chain A, CES1 protein	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
Lysosomal acid glucosylceramidase	0	0	1	1
Protein kinase C alpha type	0	1	0	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Steroid hormone receptor ERR1	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
Protein kinase C eta type	0	1	0	1
Emopamil-binding protein-like	0	1	0	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
polyadenylate-binding protein 1	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Tetracycline resistance protein, class B	0	0	0	1
Multidrug transporter MdfA	0	1	0	1
Neutrophil collagenase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Protein-arginine deiminase type-4	0	2	0	2
Solute carrier family 22 member 7	0	0	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Interleukin-8	0	1	0	1
Chain A, Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	0	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Cytochrome P450 4B1	0	1	0	1
Cytochrome P450 2A7	0	1	0	1
Cytochrome P450 2F1	0	1	0	1
Cytochrome P450 2C18	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
Cytochrome P450 4F8	0	1	0	1
Cytochrome P450 4A11	0	1	0	1
Cytochrome P450 4F3	0	1	0	1
Cytochrome P450 4A22	0	1	0	1
Vitamin D 25-hydroxylase	0	1	0	1
Cytochrome P450 2U1	0	1	0	1
Cytochrome P450 2W1	0	1	0	1
Cytochrome P450 2S1	0	1	0	1
Cytochrome P450 3A43	0	1	0	1
REST corepressor 3	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose	0	1	0	1
Trehalose-phosphatase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor gamma	0	2	2	7
Nuclear receptor ROR-alpha	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Coagulation factor XIII A chain	0	1	0	1
Fatty-acid amide hydrolase 2	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Chain A, Arginase 1	0	1	0	1
Glycoprotein	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
2-5A-dependent ribonuclease	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
DNA topoisomerase 1	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(5)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (4,043)

Protein Targets (2,721)

Nicotine Addiction

Synonyms(5)

Research Excerpts

Overview

Context

Actions

Treatment

Research

Studies (4,043)

Drugs Studied (562)

Protein Targets (2,721)