Page last updated: 2024-09-27

Osteogenesis Imperfecta

COLLAGEN DISEASES characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. Most types are autosomal dominant and are associated with mutations in COLLAGEN TYPE I.

Synonyms(1)

Synonym
Osteogenesis Imperfecta

Research Excerpts

Overview

ExcerptReference
"Bovine osteogenesis imperfecta is a congenital disease in Holstein cattle having several characteristics in common with human osteogenesis imperfecta syndromes."( Conn, KM; Cruz, JB; Drum, MA; Fisher, LW; Hawkins, GR; Robey, PG; Shimokawa, H; Termine, JD; Thompson, KG, 1984)
"Osteogenesis imperfecta is a clinically and genetically heterogeneous group of inherited connective tissue disorders in which bone fragility is the predominant feature."( Barsh, GS; Byers, PH, 1981)
"Osteogenesis imperfecta is a rare, inherited, connective-tissue disorder."( Chan, CC; de la Cruz, ZC; Green, WR; Hillis, A, 1982)
"In general, osteogenesis imperfecta is caused by heterozygous mutations in either of the genes encoding the alpha 1 or alpha 2 chains of type I collagen (COL1A1 and COL1A2, respectively)."( Dalgleish, R; De Paepe, A; Mackay, K; Punnett, HH; Rose, NJ; Steinmann, B, 1994)
"The mild form of osteogenesis imperfecta is caused by quantitative anomalies of Type I collagen."( Cole, WG, 1997)
"Severe osteogenesis imperfecta is a disorder characterized by osteopenia, frequent fractures, progressive deformity, loss of mobility, and chronic bone pain."( Bishop, NJ; Chabot, G; Glorieux, FH; Lanoue, G; Plotkin, H; Travers, R, 1998)
"Perinatal lethal osteogenesis imperfecta is the result of heterozygous mutations of the COL1A1 and COL1A2 genes."( Freising, P; Gomez Lira, M; Lisi, V; Mottes, M; Valli, M; Zolezzi, F, 1998)
"Osteogenesis imperfecta is a hereditary disease of the connective tissue, associated with bone fragility, bluish colouring of the sclerae, loss of hearing and dental anomalies."( Crivellari, R; Dottori, V; Parodi, E; Passerone, G; Podestà, A, 2000)
"Osteogenesis imperfecta is an inherited disorder of the connective tissue whose primary manifestation is an increased susceptibility to fractures."( Stynowick, GA; Tobias, JD, 2007)
"Osteogenesis Imperfecta is a heritable disorder characterized by bone fragility and low bone mass, with a wide spectrum of clinical expression."( Glorieux, FH, 2008)
"Moderate to severe osteogenesis imperfecta is associated with multiple fractures in childhood."( Ahmed, F; Bishop, N; Campbell, M; Chapman, S; Eastell, R; Hall, C; Harrison, R; Hill, C; Knowles, E; Rigby, A; Shaw, N; Sprigg, A, 2010)
"Osteogenesis imperfecta is characterised by bone fragility leading to fracture and bone deformity, chronic bone pain and reduced mobility."( Bishop, N, 2010)
"Osteogenesis imperfecta is a bone disorder in which three factors that influence bone strength (quality, mass, and geometry of osseous tissue) are affected."( Jain, E; Kumar, S; Natrajan, M; Valiathan, A, 2013)
"Children with osteogenesis imperfecta are often treated with intravenous bisphosphonates."( Adami, S; Ahmed, SF; Antón, J; Arundel, P; Bishop, N; Burren, CP; Devogelaer, JP; Hangartner, T; Hosszú, E; Lane, JM; Lorenc, R; Mäkitie, O; Munns, CF; Paredes, A; Pavlov, H; Plotkin, H; Raggio, CL; Reyes, ML; Schoenau, E; Semler, O; Sillence, DO; Steiner, RD, 2013)
"Osteogenesis imperfecta is a heritable group of collagen-related disorders that affects up to 50,000 people in the United States."( Cepela, DJ; Lozman, J; Roberts, TT; Uhl, RL, 2016)
"Osteogenesis imperfecta is a heritable disorder of bone connective tissue."( Henderson, BD; Isaac, N; Khiba, S; Mabele, O; Mokoena, T; Nkayi, A, 2016)
"Osteogenesis imperfecta is caused by qualitative or quantitative defects in type I collagen."( Cruz, AI; Daniels, AH; DeFroda, SF; Gil, JA; Sindhu, K, 2017)
"Osteogenesis imperfecta is a genetic disorder of connective tissue causing mostly left-sided heart valves and aortic root pathologies, but a coronary artery involvement reflecting an increased sensitivity to cardiovascular risk factors is also suspected in this patient population."( Dincq, AS; Hanet, C; Melly, L; Rondelet, B, 2017)
"Osteogenesis imperfecta is a genetically and phenotypically heterogeneous disorder related to a defect or deficiency in the production of type I collagen."( Franzone, JM; Kruse, RW; Shah, SA; Wallace, MJ, 2019)
"BACKGROUND Osteogenesis imperfecta is a rare inherited connective tissue disorder that is mainly characterized by long bone deformities and increased susceptibility to bone fractures."( Delniotis, I; Leidinger, B, 2019)
"Osteogenesis imperfecta is characterised by low bone mineral density, bone fragility, fractures and deformity."( Goel, A; Johari, A; Shah, I; Shetty, NS, 2021)

Treatment

ExcerptReference
"Calcitonin has been helpful in the treatment of osteogenesis imperfecta tarda inhibiting bone mineral resorption."( Lanes, R; Obregon, O; Toledo, T, 1983)
"To find an effective symptomatic treatment for osteogenesis imperfecta (OI)."( Aström, E; Söderhäll, S, 2002)
"Pamidronate seems useful in the treatment of osteogenesis imperfecta in children, since it increases BMD and reduces the fracture rate, in keeping with the findings from the larger series studied by Glorieux."( Giraud, F; Meunier, PJ, 2002)
"The complex treatment of Osteogenesis imperfecta should include alendronate and calcitriol to decrease fractures and improve bone mineral density."( Haviko, T; Maasalu, K; Märtson, A, 2003)
"Bisphosphonates are now widely used to treat children with osteogenesis imperfecta (OI)."( Arikoski, P; Bishop, NJ; Silverwood, B; Tillmann, V, 2004)
"Classic treatments of osteogenesis imperfecta for children and adults include rehabilitation therapy and orthopedic surgery."( Chevrel, G; Cimaz, R, 2006)
"Bisphosphonates are used in the treatment of osteogenesis imperfecta (OI), an inherited disorder characterized by bone fragility and low bone mass."( Celli, M; D'Eufemia, P; Finocchiaro, R; Mari, E; Persiani, P; Tetti, M; Villani, C; Zambrano, A; Zicari, A, 2008)
"neridronate in the treatment of osteogenesis imperfecta (OI)."( Adami, G; Bertoldo, F; Fassio, A; Gatti, D; Idolazzi, L; Orsolini, G; Rossini, M; Viapiana, O, 2017)
"He was treated for osteogenesis imperfecta (OI; zolendronate, calcium and vitamin D) and showed clinical improvement."( Ekbote, V; Karguppikar, MB; Khadilkar, A; Khadilkar, V, 2020)

Research

Studies (886)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990291 (32.84)23.3326
1990's144 (16.25)12.5806
2000's206 (23.25)18.1394
2010's192 (21.67)28.8240
2020's53 (5.98)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
acetone0low10
adenine0low10
ammonium hydroxide0low10
chlorine0low20
salicylic acid0low10
2-aminoadipic acid0low10
creatine0medium11
lactic acid0low10
glycine0low1060
glycerol0low10
histamine0low10
hydrogen0low10
iodine0low20
phosphorylethanolamine0low10
taurine0low10
thiamine0low10
uric acid0low20
urea0low10
2,2'-dipyridyl0low20
aminopropionitrile0low10
acetaminophen0low20
acetazolamide0low10
alendronate0medium3911
amitriptyline0low10
aspirin0low10
baclofen0low10
bupivacaine0low20
carbamazepine0low20
clonidine0medium21
dantrolene0low10
erythrosine0low10
etidronate0medium74
fentanyl0low20
fluorouracil0low20
furosemide0low20
gabapentin0low10
haloperidol0low10
ethidium0low10
ibuprofen0low10
ifosfamide0low10
2-propanol0low30
ketamine0low20
mefenamic acid0low10
midazolam0low10
minoxidil0low10
mitoxantrone0low10
activins0low10
pamidronate0medium16337
4-phenylbutyric acid0low30
propofol0low30
sevoflurane0low20
sodium fluoride0medium61
risedronic acid0medium64
succinylcholine0low20
ticlopidine0low10
prednisolone0low20
hydroxyproline0medium521
thyroxine0low20
penicillamine0low10
androsterone0low10
alanine0low70
serine0low190
aspartic acid0low100
lysine0low220
ethinyl estradiol0low10
adenosine diphosphate0low40
galactose0low20
levodopa0low10
edetic acid0low20
tyrosine0low20
adenosine monophosphate0low20
leucine0low10
methionine0low20
ampicillin0low10
cytarabine0low10
ornithine0low10
asparagine0low10
histidine0low30
valine0low110
tryptophan0low20
arginine0low180
perflutren0low10
thiophenes0low30
framycetin0low10
iodohippuric acid0low10
copper phthalocyanine0low10
catechin0low50
cyclopentane0low10
pyrazines0low10
hydrazine0low10
azacitidine0low10
methysergide0low10
nandrolone0low10
cyanogen bromide0low250
c.i. 425100low10
ethylnitrosourea0low10
calcium lactate0low10
durapatite0low40
sodium hydroxide0low10
fucose0low10
mannose0low20
carbonates0low20
enbucrilate0low10
titanium0low10
gadolinium0low10
galactosamine0low10
tricalcium phosphate0low50
silver nitrate0low10
chlorine0low10
galactose0low10
trolamine salicylate0low100
clodronic acid0low10
levamisole0low10
fluorides0low210
4-methoxyamphetamine0low10
glutamic acid0low20
tramadol0low10
vecuronium bromide0low10
1-carboxyglutamic acid0low10
epirubicin0low10
propiconazole0low10
captopril0low20
colforsin0low10
fomesafen0low10
clopidogrel0low10
remifentanil0low20
ibandronic acid0medium21
potassium phosphate0low10
fluorexon0low10
delphinidin0low10
6-amino-1-hydroxyhexane-1,1-diphosphonate0medium176
c.i. direct red 800low10
2-nitro-5-thiocyanobenzoic acid0low10
3,4-dehydroproline0low10
foxes0low10
pyridinoline0medium101
deoxypyridinoline0medium92
pentosidine0low10
technetium tc 99m hydroxymethylene diphosphonate0low10
5,5'-dihydroxylysylnorleucine0low10
methotrexate0low20
proline0low260
carbodiimides0low10
biotin0low10
olpadronic acid0medium32
cortisone0low20
taurochenodeoxycholic acid0low10
bortezomib0low10
glycogen0low20
n-acetylneuraminic acid0low10
glucosamine0low20
elastin0low30
tartaric acid0low20
retinol0low30
tacrolimus0low10
cerivastatin0low10
keratan sulfate0low10
melphalan0low10
bromochloroacetic acid0low20
glycosides0low20
pyrophosphate0low90
enclomiphene0low10
thiourea0low10
digoxin0low10
dermatan sulfate0low10
hydroxylysine0low220
3-aminolevamisole0low10
nitinol0low10
alpha-chymotrypsin0low40
17-ketosteroids0low10
osteoprotegerin0low40
dinoprostone0low20
calcitriol0low50
vitamin k semiquinone radical0low10
cholecalciferol0medium31
phenylephrine hydrochloride0low40
sirolimus0low20
brefeldin a0low10
morphine0low20
deamino arginine vasopressin0low10
dexmedetomidine0low20
strontium0low50
cysteine0low360
phosphorus0medium312
strontium radioisotopes0low20
25-hydroxyvitamin d 20low20
salubrinal0low10
oxalates0low30
24,25-dihydroxyvitamin d 30low10
24,25-dihydroxyvitamin d20low10
ursodoxicoltaurine0low10
3-hydroxyproline0low20
losartan potassium0low10
dihydrotachysterol0low10
acid phosphatase0low170
jaw0low20
calcitonin0low10
(prolyl-hydroxylprolyl-glycine)100low20
oligonucleotides0low20
c-peptide0low10
natriuretic peptide, c-type0low20
glycolipids0low10
piperidines0low20
lp5334010low10
chondroitin0low30
heparitin sulfate0low20
ascorbic acid0medium141
tetracycline0low40
chlortetracycline0low10
demeclocycline0low10
transforming growth factor beta0medium151
araldite0low10
hyaluronoglucosaminidase0low10
vitamin b 120low10
bmn 1110low10
technetium tc 99m medronate0low20
thromboplastin0low20
chondroitin sulfates0low30
exudates0low10
guanine0low10
sildenafil citrate0low10
cytidylyl-3'-5'-guanosine0low20
alcian blue0low10
eye0low60
phosphorus radioisotopes0low20
leptin0low10

Protein Targets (1,842)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit100010
RAR-related orphan receptor gamma400040
GLI family zinc finger 3370037
AR protein540054
aldehyde dehydrogenase 1 family, member A1240024
retinoic acid nuclear receptor alpha variant 1430043
retinoid X nuclear receptor alpha290029
estrogen nuclear receptor alpha580058
peroxisome proliferator-activated receptor delta210021
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a230023
activating transcription factor 6130013
v-jun sarcoma virus 17 oncogene homolog (avian)210021
Histone H2A.x170017
thyroid hormone receptor beta isoform a160016
heat shock protein beta-1110011
nuclear factor erythroid 2-related factor 2 isoform 1370037
lamin isoform A-delta10400040
Voltage-dependent calcium channel gamma-2 subunit210021
Glutamate receptor 2212124
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, JmjC domain-containing histone demethylation protein 3A100010
Chain A, 2-oxoglutarate Oxygenase110011
thioredoxin reductase320032
Fumarate hydratase110011
apical membrane antigen 1, AMA18008
nuclear receptor subfamily 1, group I, member 3270027
progesterone receptor270027
glucocorticoid receptor [Homo sapiens]410041
estrogen-related nuclear receptor alpha460046
farnesoid X nuclear receptor220022
pregnane X nuclear receptor320032
polyprotein110011
bromodomain adjacent to zinc finger domain 2B6006
peroxisome proliferator activated receptor gamma260026
arylsulfatase A180018
euchromatic histone-lysine N-methyltransferase 2550055
Caspase-74004
Bloom syndrome protein isoform 1190019
runt-related transcription factor 1 isoform AML1b1001
chromobox protein homolog 1330033
caspase-34004
core-binding factor subunit beta isoform 21001
importin subunit beta-1 isoform 18008
DNA polymerase beta4004
snurportin-18008
geminin420042
C-C chemokine receptor type 10112
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha0101
Protein farnesyltransferase subunit beta0101
C-C chemokine receptor type 50112
C-C chemokine receptor type 80011
Methionine aminopeptidase 10011
Deoxyhypusine hydroxylase0101
Transmembrane prolyl 4-hydroxylase0101
ATP-dependent phosphofructokinase220022
Glutamate receptor ionotropic, NMDA 1 011319
5-hydroxytryptamine receptor 2C0618
5-hydroxytryptamine receptor 2A0718
5-hydroxytryptamine receptor 1A010111
5-hydroxytryptamine receptor 1B0819
5-hydroxytryptamine receptor 1D0314
5-hydroxytryptamine receptor 1F0314
5-hydroxytryptamine receptor 2B0516
5-hydroxytryptamine receptor 60112
Sodium-dependent serotonin transporter010111
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 7 0213
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0112
5-hydroxytryptamine receptor 4 0112
5-hydroxytryptamine receptor 3B0112
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE280028
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
mitogen-activated protein kinase 16006
survival motor neuron protein isoform d130013
Histone deacetylase 30404
Histone deacetylase 40303
Histone deacetylase 10404
Histone deacetylase 70303
Histone deacetylase 20404
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80404
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60404
Histone deacetylase 90303
Histone deacetylase 50303
Geranylgeranyl pyrophosphate synthase0809
Farnesyl pyrophosphate synthase012012
ATAD5 protein, partial150015
GLS protein190019
Microtubule-associated protein tau140014
Smad3110011
thyroid stimulating hormone receptor180018
EWS/FLI fusion protein220022
aryl hydrocarbon receptor160016
thyroid hormone receptor beta isoform 2340034
peripheral myelin protein 22250025
cytochrome P450 3A4 isoform 1160016
Gamma-aminobutyric acid receptor subunit pi166123
ATP-binding cassette sub-family C member 3030030
Multidrug resistance-associated protein 4031033
Solute carrier family 22 member 60606
Carbonic anhydrase 1207117
UDP-glucuronosyltransferase 1A90104
Bile salt export pump08010
Bile salt export pump048050
Cytochrome P450 2B10203
Cytochrome P450 1A10001
Carbonic anhydrase 1019136
Carbonic anhydrase 2019237
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20103
Prostaglandin G/H synthase 10415
Carbonic anhydrase 306115
Cytochrome P450 3A4013218
Cytochrome P450 2D60606
Cytochrome P450 2C9 013014
Polyunsaturated fatty acid lipoxygenase ALOX150505
Gamma-aminobutyric acid receptor subunit beta-1166123
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta166123
Gamma-aminobutyric acid receptor subunit gamma-2166325
UDP-glucuronosyltransferase 1-60102
Gamma-aminobutyric acid receptor subunit alpha-5166123
Gamma-aminobutyric acid receptor subunit alpha-3166123
Arachidonate 5-lipoxygenase-activating protein0202
UDP-glucuronosyltransferase 1A1 0305
Carbonic anhydrase 4010119
Prostaglandin G/H synthase 1010010
Carbonic anhydrase 608117
Gamma-aminobutyric acid receptor subunit gamma-1166123
Gamma-aminobutyric acid receptor subunit alpha-2166123
Gamma-aminobutyric acid receptor subunit alpha-4166123
Gamma-aminobutyric acid receptor subunit gamma-3166123
Gamma-aminobutyric acid receptor subunit alpha-6166123
Carbonic anhydrase 5A, mitochondrial06116
Prostaglandin G/H synthase 209010
Carbonic anhydrase 706115
Nuclear receptor ROR-gamma101112
Cytochrome P450 2J20808
Gamma-aminobutyric acid receptor subunit alpha-1167326
Gamma-aminobutyric acid receptor subunit beta-3166123
Gamma-aminobutyric acid receptor subunit beta-2166325
Carbonic anhydrase 907117
GABA theta subunit166123
Canalicular multispecific organic anion transporter 1029029
Carbonic anhydrase 1507013
Carbonic anhydrase 1305012
Gamma-aminobutyric acid receptor subunit epsilon166123
Carbonic anhydrase 1407117
Carbonic anhydrase 5B, mitochondrial06116
toxin B0001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE140014
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase130013
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0202
GALC protein6006
cytochrome P450 family 3 subfamily A polypeptide 4280028
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
muscleblind-like protein 1 isoform 15005
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Glycogen phosphorylase, muscle form0101
Renin0303
Carbonic anhydrase 20202
Cathepsin B0101
Steryl-sulfatase0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80303
Cytochrome P450 2A60101
Androgen receptor0707
Translocator protein0213
Cannabinoid receptor 10101
Cytochrome P450 2B60617
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10509
Serum paraoxonase/arylesterase 10303
Dipeptidyl peptidase 40001
Endochitinase0101
Adenosine receptor A2a0419
Delta-type opioid receptor0506
Cytochrome P450 2C190606
Delta-type opioid receptor0719
Mu-type opioid receptor09214
Carbonic anhydrase06011
Kappa-type opioid receptor0617
Carbonic anhydrase0101
D(1A) dopamine receptor4206
Corticosteroid 11-beta-dehydrogenase isozyme 10202
Carbonic anhydrase0107
D(2) dopamine receptor0404
Cholinesterase0303
Carbonic anhydrase 0101
Mu-type opioid receptor0718
Fatty-acid amide hydrolase 10404
Beta-carbonic anhydrase 10202
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B09317
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0107
Carbonic anhydrase 30202
Carbonic anhydrase0108
Carbonic anhydrase0108
Carbonic anhydrase 0101
Sigma intracellular receptor 20202
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10516
Renin0101
Carbonic anhydrase 0107
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130317
Carbonic anhydrase 40206
Acidic mammalian chitinase0101
Carbonic anhydrase 70101
Carbonic anhydrase 0202
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
TDP1 protein380038
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
nuclear factor erythroid 2-related factor 2 isoform 2110011
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 12002
Cyclin-dependent kinase 10112
Heat shock protein HSP 90-beta0214
Xanthine dehydrogenase/oxidase0202
TAR DNA-binding protein 43121013
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 5140014
Ataxin-2170017
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
regulator of G-protein signaling 4170017
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70022
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
2-dehydropantoate 2-reductase0224
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0202
Mu-type opioid receptor09516
Delta-type opioid receptor0529
Kappa-type opioid receptor07211
Endoplasmin0112
P2Y purinoceptor 20022
Phosphatidylinositol 4-kinase alpha0202
P2X purinoceptor 10011
P2Y purinoceptor 10022
P2Y purinoceptor 10022
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 14004
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
Phosphatidylinositol 4-kinase type 2-beta0202
P2Y purinoceptor 110022
Phosphatidylinositol 4-kinase type 2-alpha0202
P2Y purinoceptor 120011
Sensor protein kinase WalK0101
Phosphatidylinositol 4-kinase beta0202
P2X purinoceptor 20011
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20012
Transient receptor potential cation channel subfamily M member 20202
Alcohol dehydrogenase E chain0202
Alcohol dehydrogenase S chain0202
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0405
Fructose-1,6-bisphosphatase 10101
Inosine-5'-monophosphate dehydrogenase0101
Proto-oncogene tyrosine-protein kinase Src0112
Amine oxidase [flavin-containing] B0101
5'-nucleotidase0001
Choline O-acetyltransferase0101
Adenylate kinase 2, mitochondrial0102
GTP:AMP phosphotransferase AK3, mitochondrial0001
Adenosine receptor A10112
Adenylate kinase isoenzyme 1 0102
5'-AMP-activated protein kinase subunit gamma-10034
5'-AMP-activated protein kinase catalytic subunit alpha-20012
Adenylate kinase 2, mitochondrial0012
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10034
Adenosine deaminase-like protein0001
Protease 0314
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30012
5'-AMP-activated protein kinase subunit gamma-20023
5'-AMP-activated protein kinase subunit beta-10023
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0004
Proton-coupled amino acid transporter 109010
Adenosine deaminase0001
Chain A, farnesyl pyrophosphate synthase0101
Acetylcholinesterase0303
Hypoxanthine-guanine phosphoribosyltransferase0303
Farnesyl pyrophosphate synthase 0606
Farnesyl pyrophosphate synthase 0303
Lysyl oxidase homolog 20101
Protein-lysine 6-oxidase0101
Protein-lysine 6-oxidase0101
Lysyl oxidase homolog 20101
Lysyl oxidase homolog 30101
Lysyl oxidase homolog 40101
Lysyl oxidase homolog 20101
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
USP1 protein, partial220022
NFKB1 protein, partial7007
cytochrome P450 2D6140014
cytochrome P450 2D6 isoform 16006
D(1A) dopamine receptor7007
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase mTOR isoform 16006
muscarinic acetylcholine receptor M1120012
Solute carrier family 22 member 1 011015
Polyunsaturated fatty acid lipoxygenase ALOX15B6006
Voltage-dependent L-type calcium channel subunit alpha-1F0303
5-hydroxytryptamine receptor 4012012
Albumin0044
High affinity nerve growth factor receptor0134
Aldo-keto reductase family 1 member B1013013
Muscarinic acetylcholine receptor M20808
Muscarinic acetylcholine receptor M40707
Muscarinic acetylcholine receptor M10404
Muscarinic acetylcholine receptor M30404
Muscarinic acetylcholine receptor M40404
Muscarinic acetylcholine receptor M50404
Muscarinic acetylcholine receptor M50606
Alpha-2A adrenergic receptor013316
Muscarinic acetylcholine receptor M20404
Muscarinic acetylcholine receptor M10808
Angiotensin-converting enzyme0708
D(2) dopamine receptor07110
Alpha-2B adrenergic receptor012214
Alpha-2C adrenergic receptor011213
Muscarinic acetylcholine receptor M30505
D(1A) dopamine receptor0607
D(1B) dopamine receptor0304
UDP-glucuronosyltransferase 1A40104
Sodium-dependent noradrenaline transporter 012012
Histamine H2 receptor0527
Alpha-1D adrenergic receptor0718
5-hydroxytryptamine receptor 2A0808
5-hydroxytryptamine receptor 2C012012
Histamine H1 receptor0516
Histamine H1 receptor0729
D(3) dopamine receptor09112
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 4 subunit alpha0405
UDP-glucuronosyltransferase 1A30003
5-hydroxytryptamine receptor 2B010010
Alpha-1A adrenergic receptor010111
Histamine H2 receptor91113
5-hydroxytryptamine receptor 60707
5-hydroxytryptamine receptor 70505
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Sodium-dependent dopamine transporter 0606
Potassium voltage-gated channel subfamily H member 20909
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0404
Nuclear receptor subfamily 3 group C member 3 0404
Sodium channel protein type 2 subunit alpha0202
Sigma non-opioid intracellular receptor 1011112
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0202
Sodium channel protein type 8 subunit alpha0202
Histamine H3 receptor0224
Sodium channel protein type 10 subunit alpha0202
Chain A, Mutant Al2 6e7p9g0011
Chain A, ATP-DEPENDENT DNA HELICASE Q18008
Chain A, Cruzipain8008
Beta-lactamase 0001
acid sphingomyelinase3003
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20113
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 19009
DNA polymerase eta isoform 16006
DNA polymerase iota isoform a (long)200020
DNA polymerase kappa isoform 1200020
60 kDa heat shock protein, mitochondrial0303
Beta-lactamase OXA-70001
Solute carrier family 15 member 10303
Solute carrier family 15 member 10202
Spike glycoprotein150015
10 kDa heat shock protein, mitochondrial0303
Angiopoietin-1 receptor0011
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Thiosulfate sulfurtransferase0303
Metallo-beta-lactamase VIM-130102
Efflux transporter 0001
Beta-lactamase 0001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0001
60 kDa chaperonin 0303
Metallo-beta-lactamase0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
10 kDa chaperonin 0303
Metallo-b-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Histamine H3 receptor0102
Beta-lactamase class B VIM-2 0113
Beta-lactamase VIM-1 0102
Chain A, retinol dehydratase0101
acetylcholinesterase150015
estrogen receptor 2 (ER beta)160016
histone acetyltransferase KAT2A isoform 1160016
Sex hormone-binding globulin0044
Corticosteroid-binding globulin0404
Glucose-6-phosphate 1-dehydrogenase0303
Solute carrier organic anion transporter family member 1A10204
G-protein coupled bile acid receptor 10033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
phosphopantetheinyl transferase200020
alpha-galactosidase4004
cytochrome P450 2C19 precursor6006
flap endonuclease 1130013
lethal factor (plasmid)130013
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase110011
vitamin D (1,25- dihydroxyvitamin D3) receptor210021
IDH1180018
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Polyphenol oxidase 20205
Pancreatic alpha-amylase0202
Albumin0202
Urease0304
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0202
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Neutral amino acid transporter A0404
Neutral amino acid transporter B(0)0404
Carbonic anhydrase-like protein, putative0008
Amino acid transporter0404
Chain A, Ferritin light chain130013
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor ionotropic, NMDA 2A 08316
Glutamate receptor ionotropic, NMDA 2C08316
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Glutamate receptor ionotropic, NMDA 2D08316
Glutamate receptor ionotropic, NMDA 3B08316
Glutamate receptor ionotropic, NMDA 3A08316
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 88008
hypothetical protein, conserved3003
glucocerebrosidase6006
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0303
Prostaglandin G/H synthase 2 0202
Epidermal growth factor receptor0718
Fatty acid-binding protein, liver0303
Integrin beta-36118
Myeloperoxidase0303
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb6118
Glutathione hydrolase 1 proenzyme0101
Substance-P receptor0303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0202
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20404
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0303
Solute carrier family 22 member 200505
Solute carrier family 22 member 60505
Sigma non-opioid intracellular receptor 10314
glp-1 receptor, partial140014
pregnane X receptor100010
PPM1D protein7007
Thrombopoietin5005
67.9K protein120012
Parkin2002
thyroid stimulating hormone receptor150015
peripheral myelin protein 22 isoform 18008
hemoglobin subunit beta3003
cellular tumor antigen p53 isoform a7007
huntingtin isoform 24004
ras-related protein Rab-9A4004
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
Interferon beta210021
Cellular tumor antigen p53290029
Adenosine receptor A30505
DNA (cytosine-5)-methyltransferase 10101
Adenosine receptor A2a0303
Multidrug and toxin extrusion protein 10707
Histone-lysine N-methyltransferase EHMT20101
Gamma-aminobutyric acid type B receptor subunit 20224
Gamma-aminobutyric acid type B receptor subunit 20303
Gamma-aminobutyric acid type B receptor subunit 10224
Gamma-aminobutyric acid type B receptor subunit 10202
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
nonstructural protein 10202
green fluorescent protein, partial0101
vitamin D3 receptor isoform VDRA160016
insulin-degrading enzyme isoform 10011
Streptavidin0011
Receptor-type tyrosine-protein phosphatase beta0001
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110101
caspase 7, apoptosis-related cysteine protease7007
caspase-37007
nuclear receptor subfamily 1, group I, member 25005
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70101
26S proteasome non-ATPase regulatory subunit 30101
Prothrombin0325
Chymotrypsinogen A0202
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10102
Chymase0101
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
Proteasome subunit beta type-80101
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50203
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100101
26S proteasome regulatory subunit 6B0112
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20102
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60101
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20101
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
ATP-dependent Clp protease proteolytic subunit0112
NACHT, LRR and PYD domains-containing protein 3 0202
Proteasome subunit alpha-type 80101
Proteasome subunit beta type-70101
26S proteasome non-ATPase regulatory subunit 10101
26S proteasome non-ATPase regulatory subunit 130101
PAX80002
NPC intracellular cholesterol transporter 1 precursor3003
major prion protein preproprotein Prp precursor0101
nuclear receptor subfamily 0 group B member 10202
steroidogenic factor 10202
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Potassium channel subfamily K member 90101
Chain A, Vitamin D Nuclear Receptor0011
Vitamin D3 receptor0011
nuclear receptor ROR-gamma isoform 1120012
Vitamin D-binding protein0011
Androgen receptor0303
Vitamin D3 receptor0239
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0033
Vitamin D3 receptor0022
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0202
Vitamin D3 receptor A0022
Chain A, angiotensin converting enzyme0101
Chain A, angiotensin converting enzyme0101
15-lipoxygenase, partial9009
M-phase phosphoprotein 88008
transient receptor potential cation channel subfamily V member 12002
Neprilysin0101
Neprilysin0101
Leukotriene A-4 hydrolase0213
EEF1AKMT4-ECE2 readthrough transcript protein0101
Angiotensin-converting enzyme 0415
Leukotriene A-4 hydrolase0101
Thymidine phosphorylase0011
Endothelin-converting enzyme 10101
Succinyl-diaminopimelate desuccinylase0303
Angiotensin-converting enzyme0202
Beta-lactamase TEM0101
Beta-lactamase 0304
Beta-lactamase 0303
Angiotensin-converting enzyme 2 0101
Vpr5005
Major prion protein0022
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
UDP-glucuronosyltransferase 2B70207
Frizzled-80011
P2X purinoceptor 40101
neuropeptide S receptor isoform A3003
Arginase 0202
Pancreatic triacylglycerol lipase0101
Sucrase-isomaltase, intestinal0101
Melatonin receptor type 1A0011
Melatonin receptor type 1B0011
Death-associated protein kinase 10101
Beta-secretase 10101
Dihydroorotate dehydrogenase 0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Insulin receptor 0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
P2Y purinoceptor 120404
Protein-arginine deiminase type-40404
Luciferase150015
60 kDa chaperonin0202
Glycine receptor subunit alpha-10022
Type IV secretion-like conjugative transfer relaxase protein TraI 0202
72 kDa type IV collagenase0303
Stromelysin-10314
Matrix metalloproteinase-90202
Macrophage metalloelastase0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)8008
Beta-1 adrenergic receptor 0011
Alpha-1B adrenergic receptor 0022
cytochrome P450 2C9 precursor4004
Membrane primary amine oxidase 0101
5-hydroxytryptamine receptor 3A0011
Solute carrier family 22 member 30405
5-hydroxytryptamine receptor 1A0404
Alpha-1B adrenergic receptor0909
Alpha-1A adrenergic receptor0022
D0303
D(3) dopamine receptor0404
Alpha-2B adrenergic receptor0404
Amine oxidase [flavin-containing] A0202
Alpha-2C adrenergic receptor0404
Alpha-2A adrenergic receptor0404
Alpha-1D adrenergic receptor0505
D(1B) dopamine receptor0303
Amine oxidase [flavin-containing] B0202
Adenosine receptor A2b0011
Alpha-2B adrenergic receptor0001
D(4) dopamine receptor0303
Alpha-1A adrenergic receptor0213
Alpha-1B adrenergic receptor0213
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
Alpha-2A adrenergic receptor0101
Nischarin0202
Solute carrier family 22 member 10304
Nischarin0101
nonstructural protein 17007
parathyroid hormone/parathyroid hormone-related peptide receptor precursor4004
Liver carboxylesterase 10001
Rap guanine nucleotide exchange factor 41001
G130013
histone-lysine N-methyltransferase 2A isoform 2 precursor8008
relaxin receptor 1 isoform 12002
relaxin receptor 2 isoform 11001
Nuclear receptor subfamily 1 group I member 20055
Rap guanine nucleotide exchange factor 37007
HLA class I histocompatibility antigen, B alpha chain 130013
ATP-dependent translocase ABCB109011
Solute carrier family 2, facilitated glucose transporter member 10011
Adenylate cyclase type 20112
Adenylate cyclase type 80011
Adenylate cyclase type 10112
Inositol hexakisphosphate kinase 1130013
Relaxin receptor 10011
Nuclear receptor subfamily 1 group I member 20011
cytochrome P450 2C9, partial130013
endonuclease IV5005
dopamine D1 receptor7007
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a9009
atrial natriuretic peptide receptor 1 precursor4004
Glucocorticoid receptor06112
Glycine receptor subunit alpha-10606
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Potassium voltage-gated channel subfamily A member 10011
Sodium- and chloride-dependent creatine transporter 10101
LMP1 [Human herpesvirus 4]0002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
peptidyl-prolyl cis-trans isomerase NIMA-interacting 18008
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0101
Thymidine kinase0101
Thymidylate synthase0304
Thymidine kinase0101
Deoxycytidine kinase0012
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
Deoxycytidine kinase0001
Vasopressin V2 receptor0112
Oxytocin receptor0011
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Translocator protein0101
Vasopressin V2 receptor 0112
Vascular endothelial growth factor receptor 20101
Alpha-synuclein2305
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
CREB-binding protein0101
hexokinase-4 isoform 13003
glucokinase regulatory protein3003
SMAD family member 28008
SMAD family member 38008
STAT3, partial0101
tumor necrosis factor1001
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Solute carrier organic anion transporter family member 1A40206
Sodium/potassium-transporting ATPase subunit alpha-1 0202
Sodium/potassium-transporting ATPase subunit beta-10202
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-3 0101
ATP-dependent translocase ABCB10303
Sodium/potassium-transporting ATPase subunit beta-1 0101
Replicase polyprotein 1ab0101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
ATP-dependent translocase ABCB10303
Sodium/potassium-transporting ATPase subunit alpha-20202
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10102
Solute carrier organic anion transporter family member 4C10001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1B30304
Solute carrier organic anion transporter family member 1B10304
prostaglandin E2 receptor EP2 subtype1001
Solute carrier family 22 member 20305
Solute carrier organic anion transporter family member 1A50004
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP4 subtype0101
Prostaglandin E2 receptor EP1 subtype0213
Prostaglandin E2 receptor EP1 subtype0101
Prostaglandin E2 receptor EP4 subtype0213
Prostaglandin F2-alpha receptor0011
Prostaglandin E2 receptor EP4 subtype0112
Prostaglandin E2 receptor EP3 subtype0213
Prostaglandin E2 receptor EP2 subtype0213
Prostacyclin receptor0213
Solute carrier organic anion transporter family member 2A10102
Solute carrier family 22 member 60205
Solute carrier family 22 member 70002
Prostaglandin E2 receptor EP2 subtype0101
Prostaglandin E2 receptor EP2 subtype0112
Solute carrier family 22 member 80306
Solute carrier family 22 member 70001
Solute carrier organic anion transporter family member 2A10001
Solute carrier family 22 member 110003
Solute carrier organic anion transporter family member 1B20001
Solute carrier family 22 member 70002
Eyes absent homolog 20202
Amyloid-beta precursor protein2204
chaperonin-containing TCP-1 beta subunit homolog3003
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0002
Estrogen receptor0718
Receptor tyrosine-protein kinase erbB-20202
Tyrosine-protein kinase Fyn0415
Beta-3 adrenergic receptor0202
Substance-K receptor0202
C-8 sterol isomerase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0202
Genome polyprotein 0101
Genome polyprotein 0112
thyrotropin-releasing hormone receptor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a6006
eyes absent homolog 2 isoform a2002
Flavin reductase (NADPH)0011
large T antigen0101
Reverse transcriptase/RNaseH 0101
lysosomal alpha-glucosidase preproprotein2002
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Sulfotransferase 1A10214
Aldehyde oxidase0101
Nuclear receptor subfamily 1 group I member 3 0101
Multidrug and toxin extrusion protein 20303
Estrogen receptor beta0415
potassium voltage-gated channel subfamily H member 2 isoform d9009
D(4) dopamine receptor0316
Kappa-type opioid receptor0517
Mu-type opioid receptor0316
Multidrug resistance-associated protein 1 0103
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Solute carrier family 22 member 80001
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Menin0011
Lecithin retinol acyltransferase0101
30S ribosomal protein S60202
30S ribosomal protein S70202
50S ribosomal protein L150202
50S ribosomal protein L100202
50S ribosomal protein L110202
50S ribosomal protein L7/L120202
50S ribosomal protein L190202
50S ribosomal protein L10202
50S ribosomal protein L200202
50S ribosomal protein L270202
50S ribosomal protein L280202
50S ribosomal protein L290202
50S ribosomal protein L310202
50S ribosomal protein L31 type B0202
50S ribosomal protein L320202
50S ribosomal protein L330202
50S ribosomal protein L340202
50S ribosomal protein L350202
50S ribosomal protein L360202
30S ribosomal protein S100202
30S ribosomal protein S110202
30S ribosomal protein S120202
30S ribosomal protein S130202
30S ribosomal protein S160202
30S ribosomal protein S180202
30S ribosomal protein S190202
30S ribosomal protein S200202
30S ribosomal protein S20202
30S ribosomal protein S30202
30S ribosomal protein S40202
30S ribosomal protein S50202
30S ribosomal protein S80202
30S ribosomal protein S90202
50S ribosomal protein L130202
50S ribosomal protein L140202
50S ribosomal protein L160202
50S ribosomal protein L230202
30S ribosomal protein S150202
50S ribosomal protein L170202
50S ribosomal protein L210202
50S ribosomal protein L300202
50S ribosomal protein L60202
30S ribosomal protein S140202
30S ribosomal protein S170202
30S ribosomal protein S10202
50S ribosomal protein L180202
Lethal factor0101
50S ribosomal protein L20202
50S ribosomal protein L30202
50S ribosomal protein L240202
50S ribosomal protein L40202
50S ribosomal protein L220202
50S ribosomal protein L50202
30S ribosomal protein S210202
50S ribosomal protein L250202
50S ribosomal protein L36 20202
Protein Rev 0011
Aminoglycoside 3'-phosphotransferase 0001
Tyrosyl-DNA phosphodiesterase 10101
Fucose-binding lectin PA-IIL0202
CD209 antigen0303
Albumin0314
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Sodium/bile acid cotransporter0101
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Broad substrate specificity ATP-binding cassette transporter ABCG20406
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
transcriptional regulator ERG isoform 35005
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-10224
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10123
Gamma-aminobutyric acid receptor subunit gamma-20224
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10202
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit beta-30224
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0202
Gamma-aminobutyric acid receptor subunit alpha-50123
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Gamma-aminobutyric acid receptor subunit alpha-30123
Gamma-aminobutyric acid receptor subunit alpha-20123
Gamma-aminobutyric acid receptor subunit beta-20123
Sodium- and chloride-dependent betaine transporter0202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40123
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Gamma-aminobutyric acid receptor subunit alpha-60123
Sterol O-acyltransferase 10011
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0011
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Gamma-aminobutyric acid receptor subunit theta0101
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor2002
Metabotropic glutamate receptor 80202
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50123
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0303
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0202
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10808
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0102
Adenylate cyclase type 1 0101
Cocaine esterase0101
Transient receptor potential cation channel subfamily V member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Vitamin D-binding protein0101
HLA class I histocompatibility antigen, A alpha chain 0022
Integrin beta-10101
Beta-2 adrenergic receptor0202
Integrin alpha-40101
Carbonyl reductase [NADPH] 10001
Beta-1 adrenergic receptor0101
D(2) dopamine receptor0202
Adenylate cyclase type 30101
Sodium-dependent dopamine transporter0101
5-hydroxytryptamine receptor 3A0101
Beta-3 adrenergic receptor0101
Adenylate cyclase type 40101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
5-hydroxytryptamine receptor 2A0101
Adenylate cyclase type 80101
5-hydroxytryptamine receptor 2A0101
D(2) dopamine receptor0101
D(3) dopamine receptor0101
Gastrin/cholecystokinin type B receptor0101
AP-2 complex subunit sigma0101
N-acetyltransferase Eis0202
5-hydroxytryptamine receptor 2B0101
Adenylate cyclase type 60101
Adenylate cyclase type 50101
5-hydroxytryptamine receptor 40101
Calcitonin gene-related peptide type 1 receptor0101
Genome polyprotein 0202
Sigma intracellular receptor 20101
Zinc finger protein 6640101
Vesicular acetylcholine transporter0101
Cholecystokinin receptor type A0101
Adenylyl cyclase 7 0101
D0101
Transient receptor potential cation channel subfamily V member 40101
Transient receptor potential cation channel subfamily V member 20101
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Protein (female-specific Histamine Binding Protein 2)0011
aryl hydrocarbon receptor nuclear translocator0001
transforming acidic coiled-coil-containing protein 30001
Plasma kallikrein0005
Macrophage migration inhibitory factor0202
Histamine H1 receptor0134
Histamine H3 receptor0101
Histamine N-methyltransferase 0101
Glutaminyl-peptide cyclotransferase0202
Equilibrative nucleoside transporter 40001
Histamine H4 receptor0123
Histamine H4 receptor0123
Histamine H4 receptor 0101
Histamine H4 receptor0123
Carboxylic ester hydrolase 0001
Solute carrier family 22 member 20203
Chain A, HISTIDINE-BINDING PROTEIN0011
Histidine-binding periplasmic protein0011
Glutamine synthetase0101
Asc-type amino acid transporter 10101
Acid-sensing ion channel 30101
Dihydrofolate reductase0607
Cholinesterase0101
Fatty acid-binding protein, intestinal0101
Polyunsaturated fatty acid 5-lipoxygenase0102
Prostaglandin G/H synthase 10101
Caspase-10101
Prostaglandin G/H synthase 2 0102
Aldo-keto reductase family 1 member C30303
Caspase-30101
Caspase-40101
Caspase-50101
Caspase-90101
Acid-sensing ion channel 10101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 1 0102
Dehydrogenase/reductase SDR family member 90101
histone deacetylase 9 isoform 31001
Peptidylglycine alpha-amidating monooxygenase0001
Acetylcholinesterase0303
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Intestinal-type alkaline phosphatase0303
Phospholipase A-2-activating protein0303
Alkaline phosphatase, placental type0101
Alkaline phosphatase, tissue-nonspecific isozyme 0202
Intestinal-type alkaline phosphatase0101
WRN2002
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase2002
Tyrosine-protein kinase Lck0112
SLC16A10 protein0003
Monocarboxylate transporter 100003
phosphoglycerate kinase2002
Type-1A angiotensin II receptor 0101
Type-1B angiotensin II receptor0202
Type-2 angiotensin II receptor0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
5-hydroxytryptamine receptor 1A0101
Type-1 angiotensin II receptor0101
Tryptophan 5-hydroxylase 10101
Tryptophan 5-hydroxylase 10101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Alpha-mannosidase 2C10101
glycogen synthase kinase-3 beta isoform 10011
Aldo-keto reductase family 1 member B100101
Transient receptor potential cation channel subfamily A member 10011
Beta-lactamase0101
Myc proto-oncogene protein0101
Aldo-keto reductase family 1 member B10202
Aldo-keto reductase family 1 member C40101
Malate dehydrogenase, cytoplasmic0101
Aldo-keto reductase family 1 member C2 0202
Aldo-keto reductase family 1 member C10202
Peroxisome proliferator-activated receptor alpha1001
Large neutral amino acids transporter small subunit 1 0101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
caspase-1 isoform alpha precursor1001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10022
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0112
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20022
Bifunctional purine biosynthesis protein ATIC0202
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
Caspase-71001
Solute carrier organic anion transporter family member 1A30002
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
DNA polymerase III, partial2002
UDP-glucuronosyltransferase 2B10 0101
Chain A, Probable serine/threonine-protein kinase pknB0101
LANA0001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
phospholipase A2, group III0101
interferon gamma precursor0001
histone-lysine N-methyltransferase NSD2 isoform 10001
tyrosine-protein kinase Yes1001
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
DNA repair protein RAD52 homolog isoform a0001
pyruvate kinase PKM isoform b1001
Glycoprotein hormones alpha chain1001
Proto-oncogene tyrosine-protein kinase ROS0101
Ornithine decarboxylase1001
DNA topoisomerase 2-alpha0113
DNA topoisomerase 20001
Casein kinase II subunit alpha'0112
Guanine nucleotide-binding protein G2002
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
DNA topoisomerase 2-beta0012
Tyrosine-protein kinase BTK0112
NEDD8-activating enzyme E1 regulatory subunit0011
Integrase 0202
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
Single-stranded DNA cytosine deaminase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Proteinase-activated receptor 10112
Kappa-type opioid receptor0214
Nociceptin receptor0101
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0101
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sialidase-20101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial0101
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial0101
Chain A, ARGINASE 10101
Chain A, Arginase 10101
Chain A, ARGINASE 10101
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE0101
Cystathionine gamma-lyase0202
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Chain A, NUCLEOSIDE DIPHOSPHATE KINASE0011
luciferase0001
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Nociceptin receptor0011
Glutamate 5-kinase0001
heat shock protein HSP 90-alpha isoform 20102
heat shock protein 90, putative0001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
UDP-glucuronosyltransferase 1A80001
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Prolyl 4-hydroxylase, beta polypeptide0001
nuclear factor NF-kappa-B p105 subunit isoform 11001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
Estrogen receptor0101
Gastric inhibitory polypeptide receptor0101
Estrogen receptor beta0101
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
Retinol-binding protein 40011
Beta-lactoglobulin0011
Disintegrin and metalloproteinase domain-containing protein 172002
Butyrophilin subfamily 3 member A10023
4-hydroxy-3-methylbut-2-enyl diphosphate reductase0101
Farnesyl diphosphate synthase0101
H0202
Phosphotransferase 0101
Farnesyl diphosphate synthase0101
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polymerase acidic protein0011
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Xanthine dehydrogenase/oxidase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Pyruvate kinase PKM0011
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0213
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0426
Peptidyl-prolyl cis-trans isomerase FKBP1B0022
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50202
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Acetylcholinesterase0101
Cytochrome P450 3A50101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Splicing factor 3B subunit 30101
Chain A, Prostatic Acid Phosphatase0101
Sodium/bile acid cotransporter0002
Ileal sodium/bile acid cotransporter0202
Bile acid receptor0112
Bile salt export pump0001
90-kda heat shock protein beta HSP90 beta, partial0101
estrogen receptor beta isoform 10101
tyrosine-protein phosphatase non-receptor type 7 isoform 20101
Dihydroxyacetone phosphate acyltransferase0001
Tetracycline resistance protein, class B0001
Multidrug transporter MdfA0101
Neutrophil collagenase0202
Collagenase 30101
Cannabinoid receptor 10101
Chain A, ykoF0011
Chain B, ykoF0011
Chain A, ThiT0011
Thiamine transporter ThiT0011
Transketolase0011
Thiamine-binding periplasmic protein0011
serine/threonine-protein kinase PLK12002
isocitrate dehydrogenase 1, partial1001
serine-protein kinase ATM isoform a1001
Urease subunit alpha0202
Urease subunit alpha0101
Urease subunit beta0202
Urease subunit beta 0101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Thymidine phosphorylase0101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Phospholipase A20011
Ectonucleotide pyrophosphatase/phosphodiesterase family member 20101
Chain A, Arginase 10101
Farnesyl diphosphate synthase0101
Matrix metalloproteinase-140101
Geranylgeranyl pyrophosphate synthase0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]