Page last updated: 2024-08-05 11:16:15
pivalate ester
A carboxylic ester of pivalic acid.
ChEBI ID: 50784
Members (9)
Member | Definition | Role |
---|---|---|
clocortolone pivalate | The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders. | clocortolone pivalate |
cyenopyrafen | A member of the class of pyrazoles that is ethene in which the hydrogens at position 1 have been replaced by p-tert-butylphenyl and cyano groups, while the hydrogens at position 2 have been replaced by pivaloyloxy and 1,3,4-trimethylpyrazol-5-yl groups (the E isomer). A proacaricide (by hydrolysis of the pivalate ester linkage to give the corresponding enol), it was formerly used for the control of mites in fruit, vegetables and tea. | cyenopyrafen |
deoxycortone pivalate | 11-deoxycorticosterone pivalate | |
dipivefrin | The dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. | dipivefrin |
etilefrine pivalate | etilefrine pivalate | |
flumethasone pivalate | flumethasone pivalate | |
pinoxaden | A pyrazolooxadiazepine that is 7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin which is substituted at positions 8 and 9 by 2,6-diethyl-4-methylphenyl and pivaloyloxy groups, respectively. A pro-herbicide (by hydrolysis of the pivalate ester to give the corresponding enol), it is used for control of grass weeds in cereal crops. | pinoxaden |
sivelestat | sivelestat | |
tixocortol pivalate | The pivalate thioester of tixocortol. | tixocortol pivalate |
Research
Studies (691)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 134 (19.39) | 18.7374 |
1990's | 166 (24.02) | 18.2507 |
2000's | 150 (21.71) | 29.6817 |
2010's | 186 (26.92) | 24.3611 |
2020's | 55 (7.96) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 92 (12.50%) | 5.53% |
Reviews | 30 (4.08%) | 6.00% |
Case Studies | 76 (10.33%) | 4.05% |
Observational | 1 (0.14%) | 0.25% |
Other | 537 (72.96%) | 84.16% |