A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy.
| Member | Definition | Class |
|---|
| 1-anilino-8-naphthalenesulfonate | A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8. | 8-anilinonaphthalene-1-sulfonic acid |
| 1-palmitoyl-2-(6-(n-(7-nitrobenz)-2-oxa-1,3-diazol-4-yl)aminocaproyl)phosphatidylcholine | A 1,2-diacyl-sn-glycero-3-phosphocholine(1+) in which the acyl groups at C-1 and C-2 are hexadecanoyl and 6-[(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]hexanoyl respectively. | 1-hexadecanoyl-2-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphocholine |
| 1,5-aedans | An aminonaphthalenesulfonic acid fluorophore with a structure consisting of ethylenediamine substituted on the nitrogens with acetyl and 5-sulfonyl-1-naphthyl groups. | 5-[(2-acetamidoethyl)amino]naphthalene-1-sulfonic acid |
| 1,5-i-aedans | An aminonaphthalenesulfonic acid fluorophore with a structure consisting of ethylenediamine substituted on the nitrogens with iodoacetyl and 5-sulfonyl-1-naphthyl groups. | 5-{[2-(iodoacetamido)ethyl]amino}naphthalene-1-sulfonic acid |
| 2'(3')-o-(n-methyl)anthraniloylguanosine 5'-triphosphate | A purine ribonucleoside 5'-triphosphate that is GTP substituted at the 3' position by an N-methylanthraniloyl group. | 3'-MANT-GTP |
| 4-chloro-7-nitrobenzofurazan | A benzoxadiazole that is 2,1,3-benzoxadiazole which is substituted at position 4 by chlorine and at position 7 by a nitro group. | 4-chloro-7-nitrobenzofurazan |
| 7-hydroxycoumarin | A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7. | umbelliferone |
| filipin | A macrolide that is the major component of a mixture of four isomeric polyene macrolides isolated from Streptomyces filipinensis. | filipin III |
| lissamine rhodamine b | An organic sodium salt having 4-[3,6-bis(diethylamino)xanthenium-9-yl]benzene-1,3-disulfonate as the counterion. | lissamine rhodamine |
| n-(7-(4-nitrobenzo-2-oxa-1,3-diazole))-6-aminocaproyl sphingosine | An N-acylsphingosine that is sphingosine with the amino nitrogen converted into a 6-{[N-(7-nitrobenzo-2,1,3-oxadiazol-4-yl)amino]}hexananamido group. | N-{6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]hexanoyl}sphingosine |
| pyrene | An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system. | pyrene |
| rhodamine b | An organic chloride salt having N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium as the counterion. An amphoteric dye commonly used as a fluorochrome. | rhodamine B |
| sapintoxin d | A phorbol ester consisting of phorbol that is acylated at positions 12 and 13 by 2-(methylamino)benzoyl and acetyl groups respectively. | sapintoxin D |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 20.3866 | 1 | 2 |
| 67.9K protein | Vaccinia virus | Potency | 10.6101 | 2 | 2 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 26.2269 | 1 | 2 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 12.8920 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 2 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 35.4813 | 2 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 14.1254 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 36.9434 | 7 | 15 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 7.9433 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 80.6517 | 1 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 39.8107 | 1 | 1 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 51.4532 | 1 | 2 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 29.4548 | 2 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 50.1187 | 1 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 26.6795 | 1 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 28.1838 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 29.4548 | 2 | 3 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 50.4512 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 7.4410 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 45.6701 | 1 | 3 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 5.0119 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 27.7170 | 1 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 34.0425 | 9 | 16 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 53.2439 | 2 | 3 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 35.1907 | 8 | 19 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 28.6138 | 1 | 1 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 72.4363 | 1 | 3 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| GALC protein | Homo sapiens (human) | Potency | 1.5849 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| geminin | Homo sapiens (human) | Potency | 19.1842 | 2 | 3 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 26.5793 | 2 | 3 |
| GLS protein | Homo sapiens (human) | Potency | 10.7509 | 1 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 9.1268 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 39.9236 | 1 | 3 |
| Glycoprotein hormones alpha chain | Homo sapiens (human) | Potency | 31.6228 | 1 | 2 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 34.0620 | 1 | 2 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 22.7406 | 2 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 22.9256 | 1 | 1 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 26.9680 | 1 | 2 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 37.6214 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 47.8992 | 1 | 3 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| IDH1 | Homo sapiens (human) | Potency | 14.5810 | 1 | 1 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 59.1400 | 2 | 4 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 2.2387 | 1 | 1 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 7.9433 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 15.5920 | 2 | 3 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 0.2512 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 37.3457 | 3 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 18.3564 | 1 | 1 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 17.7828 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 37.9932 | 3 | 8 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 25.7953 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 37.3299 | 2 | 2 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 36.8396 | 2 | 3 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 11.2202 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 89.1251 | 1 | 1 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 2.5119 | 1 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 24.9204 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 62.5972 | 2 | 2 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.8489 | 2 | 2 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 81.5478 | 2 | 2 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 100.6636 | 2 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 40.9440 | 2 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| relaxin receptor 1 isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 38.2547 | 3 | 5 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 33.4345 | 2 | 4 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 10.8523 | 1 | 2 |
| Smad3 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| snurportin-1 | Homo sapiens (human) | Potency | 59.1400 | 2 | 4 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 11.7373 | 2 | 3 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 68.8205 | 2 | 3 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 28.6401 | 2 | 5 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 0.6310 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 22.3733 | 7 | 11 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 34.6713 | 1 | 1 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 20.6062 | 3 | 3 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 2.5119 | 1 | 1 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 2.5119 | 1 | 1 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 21.4911 | 2 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 38.6585 | 3 | 3 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 37.6460 | 1 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 39.9236 | 1 | 3 |
| Vpr | Human immunodeficiency virus 1 | Potency | 12.5893 | 1 | 1 |
| WRN | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 140.0000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 14,550.0000 | 2 | 2 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 22.9000 | 1 | 1 |
| B1 bradykinin receptor | Homo sapiens (human) | IC50 | 59.6400 | 1 | 1 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 59.6400 | 1 | 1 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 1,600.0000 | 4 | 4 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 46.3000 | 4 | 4 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 0.5164 | 3 | 3 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 77.5000 | 4 | 4 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 0.3662 | 4 | 4 |
| Chain A, Adenylate cyclase, type V | Canis lupus familiaris (dog) | Ki | 0.0610 | 1 | 4 |
| Chain A, RNA-directed RNA polymerase NS5 | Dengue virus 2 16681-PDK53 | IC50 | 100.0000 | 1 | 1 |
| Chain B, Adenylate cyclase, type II | Rattus norvegicus (Norway rat) | Ki | 0.0610 | 1 | 4 |
| Choline O-acetyltransferase | Homo sapiens (human) | Ki | 200.0000 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 500.0000 | 1 | 1 |
| core protein, partial | | IC50 | 49.7510 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 91.0000 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 91.0000 | 2 | 2 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 0.0410 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 0.0070 | 1 | 1 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 0.0020 | 2 | 2 |
| Dihydroorotate dehydrogenase | Leishmania major | IC50 | 484.0935 | 1 | 2 |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | Ki | 1.0000 | 1 | 1 |
| Fatty acid-binding protein, intestinal | Homo sapiens (human) | Ki | 31.1000 | 1 | 1 |
| Genome polyprotein | Hepatitis C virus (isolate BK) | IC50 | 36.6000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase | Homo sapiens (human) | IC50 | 616.5950 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | Trypanosoma cruzi | IC50 | 616.5800 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 21.0400 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 3.8100 | 1 | 1 |
| metallo beta-lactamase | Pseudomonas aeruginosa | IC50 | 59.6400 | 1 | 1 |
| metallo-beta-lactamase IMP-1 | Pseudomonas aeruginosa | IC50 | 59.6400 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | Ki | 1,000.0000 | 1 | 1 |
| nuclear receptor corepressor 2 isoform 2 | Homo sapiens (human) | IC50 | 1.0250 | 1 | 1 |
| peroxisome proliferator-activated receptor gamma isoform 2 | Homo sapiens (human) | IC50 | 1.0250 | 1 | 1 |
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | IC50 | 39.8410 | 1 | 2 |
| Polypeptide N-acetylgalactosaminyltransferase 2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 420.0000 | 1 | 1 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 141.0000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | IC50 | 43.0000 | 1 | 1 |
| Small conductance calcium-activated potassium channel protein 3 | Rattus norvegicus (Norway rat) | IC50 | 500.0000 | 1 | 1 |
| Sorbitol dehydrogenase | Homo sapiens (human) | IC50 | 120.0000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 420.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 236.0000 | 1 | 1 |
| Zn finger protein | Nicotiana tabacum (common tobacco) | Ki | 0.7540 | 1 | 1 |