A substance to which an electron may be transferred.
ChEBI ID: 17654
| Member | Definition | Class |
|---|---|---|
| acetaldehyde | The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke. | acetaldehyde |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 2,263 (39.24) | 18.7374 |
| 1990's | 942 (16.33) | 18.2507 |
| 2000's | 1,185 (20.55) | 29.6817 |
| 2010's | 1,036 (17.96) | 24.3611 |
| 2020's | 341 (5.91) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 77 (1.24%) | 5.53% |
| Reviews | 434 (6.97%) | 6.00% |
| Case Studies | 49 (0.79%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5,666 (91.01%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 47.4771 | 3 | 3 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 7.2412 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 0.8820 | 7 | 7 |
| Ataxin-2 | Homo sapiens (human) | Potency | 0.6394 | 1 | 1 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 0.6394 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 71.7403 | 1 | 1 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 71.7403 | 1 | 1 |
| caspase-3 | Homo sapiens (human) | Potency | 71.7403 | 1 | 1 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 71.7403 | 1 | 1 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 63.0124 | 2 | 2 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 5.0788 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 4.0238 | 9 | 9 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 80.4940 | 1 | 1 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 2.4352 | 6 | 6 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 62.1976 | 3 | 3 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 0.1305 | 2 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 44.8970 | 3 | 3 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 0.4034 | 1 | 1 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 57.5187 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 118.2580 | 1 | 1 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 48.0366 | 2 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 36.8811 | 2 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 64.5370 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 33.3970 | 2 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 27.8622 | 4 | 4 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 49.4845 | 3 | 3 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 4.5265 | 1 | 1 |
| progesterone receptor | Homo sapiens (human) | Potency | 28.5603 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 2.1896 | 2 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 21.4215 | 3 | 3 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 29.2422 | 2 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 21.9408 | 2 | 2 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 21.9408 | 2 | 2 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 1.3510 | 3 | 3 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 48.1090 | 4 | 4 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 42.6993 | 2 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 64.5370 | 1 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 30.7460 | 2 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 0.4034 | 1 | 1 |