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1,2,4-triazines
Any compound with a 1,2,4-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 2 and 4 of the core benzene ring structure.
ChEBI ID: 39410
Members (15)
| Member | Definition | Role |
|---|---|---|
| 1,2,4-triazine | 1,2,4-triazine | |
| 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine | 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine | |
| 3-(2,5-dimethyl-3-furanyl)-5,6-diphenyl-1,2,4-triazine | 3-(2,5-dimethyl-3-furanyl)-5,6-diphenyl-1,2,4-triazine | |
| 3-(3,5-dimethyl-1-pyrazolyl)-5-phenyl-1,2,4-triazine | 3-(3,5-dimethyl-1-pyrazolyl)-5-phenyl-1,2,4-triazine | |
| 5,6-diphenyl-3-pyridin-4-yl-1,2,4-triazine | 5,6-diphenyl-3-pyridin-4-yl-1,2,4-triazine | |
| 6-azathymine | A nucleobase analogue that is thymine in which the CH group at position 6 is replaced by nitrogen. | 6-azathymine |
| 6-methyl-3-sulfanylidene-1,2-dihydro-[1,2,4]triazolo[4,3-b][1,2,4]triazin-7-one | 6-methyl-3-sulfanylidene-1,2-dihydro-[1,2,4]triazolo[4,3-b][1,2,4]triazin-7-one | |
| azauracil | A 1,2,4-triazine compound having oxo-substituents at the 3- and 5-positions. | 6-azauracil |
| Benzo[E]pyrazolo[5,1-c][1,2,4]triazin-8-yl N,N-dimethylcarbamate | Benzo[E]pyrazolo[5,1-c][1,2,4]triazin-8-yl N,N-dimethylcarbamate | |
| ceftriaxone | A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups. | ceftriaxone |
| lamotrigine | A member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6. | lamotrigine |
| metamitron | A member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, a methyl group at position 3 and a phenyl group at position 6. | metamitron |
| metribuzin | A member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, tert-butyl group at position 6 and a methylsulfanyl group at position 3. | metribuzin |
| ml228 probe | A member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. | ML228 |
| pymetrozine | A member of the class of 1,2,4-triazines that is 4,5-dihydro-1,2,4-triazin-3(2H)-one substituted by a methyl group at position 6 and a (pyridin-3-ylmethylidene)amino group at position 4. | pymetrozine |
Research
Studies (4,066)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 122 (3.00) | 18.7374 |
| 1990's | 615 (15.13) | 18.2507 |
| 2000's | 1,524 (37.48) | 29.6817 |
| 2010's | 1,339 (32.93) | 24.3611 |
| 2020's | 466 (11.46) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 504 (11.57%) | 5.53% |
| Reviews | 620 (14.24%) | 6.00% |
| Case Studies | 692 (15.89%) | 4.05% |
| Observational | 42 (0.96%) | 0.25% |
| Other | 2,497 (57.34%) | 84.16% |