Page last updated: 2024-08-05 11:20:54

1,2,4-triazines

Any compound with a 1,2,4-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 2 and 4 of the core benzene ring structure.

ChEBI ID: 39410

Members (15)

MemberDefinitionRole
1,2,4-triazine1,2,4-triazine
3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine
3-(2,5-dimethyl-3-furanyl)-5,6-diphenyl-1,2,4-triazine3-(2,5-dimethyl-3-furanyl)-5,6-diphenyl-1,2,4-triazine
3-(3,5-dimethyl-1-pyrazolyl)-5-phenyl-1,2,4-triazine3-(3,5-dimethyl-1-pyrazolyl)-5-phenyl-1,2,4-triazine
5,6-diphenyl-3-pyridin-4-yl-1,2,4-triazine5,6-diphenyl-3-pyridin-4-yl-1,2,4-triazine
6-azathymineA nucleobase analogue that is thymine in which the CH group at position 6 is replaced by nitrogen.6-azathymine
6-methyl-3-sulfanylidene-1,2-dihydro-[1,2,4]triazolo[4,3-b][1,2,4]triazin-7-one6-methyl-3-sulfanylidene-1,2-dihydro-[1,2,4]triazolo[4,3-b][1,2,4]triazin-7-one
azauracilA 1,2,4-triazine compound having oxo-substituents at the 3- and 5-positions.6-azauracil
Benzo[E]pyrazolo[5,1-c][1,2,4]triazin-8-yl N,N-dimethylcarbamateBenzo[E]pyrazolo[5,1-c][1,2,4]triazin-8-yl N,N-dimethylcarbamate
ceftriaxoneA third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups.ceftriaxone
lamotrigineA member of the class of 1,2,4-triazines in which the triazene skeleton is substituted by amino groups at positions 3 and 5, and by a 2,3-dichlorophenyl group at position 6.lamotrigine
metamitronA member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, a methyl group at position 3 and a phenyl group at position 6.metamitron
metribuzinA member of the class of 1,2,4-triazines that is 1,2,4-triazin-5(4H)-one substituted by an amino group at position 4, tert-butyl group at position 6 and a methylsulfanyl group at position 3.metribuzin
ml228 probeA member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway.ML228
pymetrozineA member of the class of 1,2,4-triazines that is 4,5-dihydro-1,2,4-triazin-3(2H)-one substituted by a methyl group at position 6 and a (pyridin-3-ylmethylidene)amino group at position 4.pymetrozine

Research

Studies (4,066)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-1990122 (3.00)18.7374
1990's615 (15.13)18.2507
2000's1,524 (37.48)29.6817
2010's1,339 (32.93)24.3611
2020's466 (11.46)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials504 (11.57%)5.53%
Reviews620 (14.24%)6.00%
Case Studies692 (15.89%)4.05%
Observational42 (0.96%)0.25%
Other2,497 (57.34%)84.16%