Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
| Member | Definition | Class |
|---|
| 1-deoxynojirimycin | An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. | duvoglustat |
| 1-methylhydantoin | A imidazolidine-2,4-dione that is the N-methyl-derivative of hydantoin. | N-methylhydantoin |
| 1-octanol | An octanol carrying the hydroxy group at position 1. | octan-1-ol |
| 1-phenazinecarboxylic acid | An aromatic carboxylic acid that is phenazine substituted at C-1 with a carboxy group. | phenazine-1-carboxylic acid |
| 1-tridecanol | A long-chain primary fatty alcohol that is tridecane substituted by a hydroxy group at position 1. | tridecan-1-ol |
| 1-tuberculosinyladenosine | An organic cation that is adenosine alkylated at position N1 by a tuberculosinyl group. | 1-tuberculosinyladenosine(1+) |
| 12-aminododecanoic acid | An omega-amino fatty acid that is dodecanoic acid in which one of the terminal amino hydrogens has been replaced by an amino group. | 12-aminododecanoic acid |
| 2-aminophenol | The aminophenol which has the single amino substituent located ortho to the phenolic -OH group. | 2-aminophenol |
| 2-eicosanol | A secondary fatty alcohol that is icosane substituted by a hydroxy group at position 2. | icosan-2-ol |
| 2-ethylfuran | A member of the class of furans that is furan in which the hydrogen atom at position 2 has been replaced by an ethyl group. | 2-ethylfuran |
| 2-ketogluconate | A ketoaldonic acid that is D-gluconic acid in which the hydroxy group at position 2 has been oxidised to a keto group. | 2-dehydro-D-gluconic acid |
| 2-methylbutanoic acid | A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria. | 2-methylbutyric acid |
| 2-methyltryptophan | An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of 2-methyl-L-tryptophan; major species at pH 7.3. | 2-methyl-L-tryptophan zwitterion; 2-methyl-L-tryptophan |
| 2-methyltryptophan | An L-tryptophan derivative in which the hydrogen at position 2 on the indole ring is replaced by a methyl group. | 2-methyl-L-tryptophan zwitterion; 2-methyl-L-tryptophan |
| 2-nonanol | A secondary alcohol that is nonane substituted by a hydroxy group at position 2. | nonan-2-ol |
| 2-pentylfuran | A member of the class of furans that is furan in which the hydrogen at position 2 is replaced by a pentyl group. It is found in many heat-processed foods and drinks. | 2-pentylfuran |
| 2,3,5-trimethylpyrazine | A member of the class of pyrazines that is pyrazine in which three hydrogens at positions 2, 3 and 5 have been replaced by methyl groups. | trimethylpyrazine |
| 2,4-di-tert-butylphenol | A member of the class of phenols carrying two tert-butyl substituents at positions 2 and 4. | 2,4-di-tert-butylphenol |
| 2,4-diacetylphloroglucinol | A benzenetriol that is phloroglucinol in which two of the ring hydrogens are replaced by acetyl groups. | 2,4-diacetylphloroglucinol |
| 2,4-dichlorobenzoic acid | A chlorobenzoic acid that is benzoic acid in which the ring hydrogens at positions 2 and 4 are substituted by chloro groups. | 2,4-dichlorobenzoic acid |
| 2,5-dimethylfuran | A member of the class of furans that is furan in which the hydrogens at positions 2 and 5 are replaced by methyl groups. | 2,5-dimethylfuran |
| 3-hydroxy-5-cholestenoic acid | A steroid acid resulting from the oxidation of one of the terminal methyl groups of cholesterol to the corresponding aldehyde. | 3beta-hydroxycholest-5-en-26-oic acid |
| 3-hydroxybenzoic acid | A monohydroxybenzoic acid that is benzoic acid substituted by a hydroxy group at position 3. It has been isolated from Taxus baccata. It is used as an intermediate in the synthesis of plasticisers, resins, pharmaceuticals, etc. | 3-hydroxybenzoic acid |
| 3-hydroxyproline | A D-proline derivative that is D-proline monohydroxylated at position 3 (the cis-3-hydroxy-diastereomer). | cis-3-hydroxy-D-proline zwitterion; cis-3-hydroxy-D-proline |
| 3,7-dihydroxytropolone | A cyclic ketone that is tropolone in which the hydrogens at positions 3 and 7 are substituted by hydroxy groups. It is isolated from the soil bacterium Streptomyces tropolofaciens strain K611-97. | 3,7-dihydroxytropolone |
| 3'-hydroxyechinenone | A member of the class of carotenone that is echinenone carrying an additional hydroxy substituent at position 3'. Found in cyanobacteria. | 3'-hydroxyechinenone |
| 32,33,34,35-bacteriohopanetetrol | A hopanoid that is bacteriohopane carrying four hydroxy substituents at positions 32, 33, 34 and 35. | bacteriohopane-32,33,34,35-tetrol |
| 4-anisaldehyde | A member of the class of benzaldehydes consisting of benzaldehyde itself carrying a methoxy substituent at position 4. | p-methoxybenzaldehyde |
| 4-hydroxyphenylglycine | A glycine molecule carrying a 4-hydroxyphenyl substituent. | 4-hydroxyphenylglycine |
| 4-hydroxyphenyllactic acid | A 2-hydroxy carboxylic acid that is lactic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. | 3-(4-hydroxyphenyl)lactic acid |
| 4-methyl-3-hydroxyanthranilic acid | An aminobenzoic acid that is anthranilic acid substituted by a hydroxy group at position 3 and a methyl group at position 4. | 3-hydroxy-4-methylanthranilic acid |
| 5-hydroxybenzimidazole | A member of the class of benzimidazoles that is 1H-benzimidazole carrying a single hydroxy substituent at position 5. | 5-hydroxybenzimidazole |
| 5-methoxysalicylic acid | A methoxysalicylic acid that is salicylic acid which is carrying a methoxy group at position 5. | 5-methoxysalicylic acid |
| 6-oxopiperidine-2-carboxylate | A delta-lactam that is piperidine-2-carboxylic acid substituted at position 6 by an oxo group. | 6-ketopiperidine-2-carboxylic acid |
| 8-hydroxyadenine | A nucleobase analogue that is adenine bearing a single hydroxy substituent at position 8. | 8-hydroxyadenine; 8-oxoadenine |
| acarbose | A chondramide that is chondramide A in which the hydrogen at position 2 of the indole moiety has been replaced by a chlorine. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide B |
| acetopyrrothine | A dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 4,5 and 6 have been replaced by methyl, oxo and acetamido groups, respectively. It is a potent inhibitor of RNA polymerases, inhibits the angiogenesis of human umbilical vein endothelial cells, and also inhibits JAMM metalloproteases. | thiolutin |
| acetylglucosamine | The D isomer of N-acetylglucosamine. | N-acetyl-D-glucosamine |
| acetylpyruvic acid | A dioxo monocarboxylic acid that is pentanoic acid carrying two oxo groups at positions 2 and 4. | acetylpyruvic acid |
| acetylspiramycin | A macrolide antibiotic produced by various Streptomyces species. | spiramycin II |
| aclarubicin | An anthracycline antibiotic that is produced by Streptomyces galilaeus and also has potent antineoplastic activity. | aclacinomycin A zwitterion; aclacinomycin A |
| adonixanthin | A carotenone that consists of beta,beta-caroten-4-one bearing two hydroxy substituents at positions 3 and 3' (the 3S,3'R diastereomer). | adonixanthin |
| albaflavenone | A carbotricyclic compound that is (+)-epi-isozizaene in which the hydrogens at position 5 have been replaced by an oxo group. | albaflavenone |
| alpha-aminopimelic acid | An amino dicarboxylic acid that is heptanedioic acid in which a hydrogen at position 2 is replaced by an amino group. It is a component of the cell wall peptidoglycan of bacteria. | 2-aminopimelic acid |
| althiomycin | A peptide antibiotic isolated from soil and enteric bacteria. It is a protein synthesis inhibitor which exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria. | althiomycin |
| aminoimidazole ribotide | A 1-(phosphoribosyl)imidazole that is 5-aminoimidazole in which the proton at position 1 has been replaced by a 5-phospho-beta-D-ribofuranosyl group. | 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole |
| amphotericin b | A macrolide antibiotic used to treat potentially life-threatening fungal infections. | amphotericin B |
| anisomycin | An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. | (-)-anisomycin |
| anticapsin | An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of anticapsin; major species at pH 7.3. | anticapsin zwitterion; anticapsin |
| anticapsin | An alanine derivative that is L-alanine bearing a 5-oxo-7-oxabicyclo[4.1.0]hept-2-yl substituent at position 3. | anticapsin zwitterion; anticapsin |
| arenaemycin e | A sesquiterpene lactone that is isolated from several Streptomyces species and exhibits antibiotic activity. | pentalenolactone |
| asukamycin | A polyketide that is a member of the manumycin family of antibiotics and exhibits strong antibacterial, antifungal, and antineoplastic activities. Isolated from from the actinomycete bacterium Streptomyces nodosus subsp. asukaensis. | asukamycin |
| aurachin a | An A-type aurichin that is 1,2-dihydrofuro[2,3-c]quinoline 5-oxide which is substituted at position 2 by a (6E)-10-hydroxy-2,6-dimethylundeca-2,6-dien-10-yl group and at position 4 by a methyl group (relative configuration shown). Found in the myxobacterium Stigmatella aurantiaca strain Sg a15. | aurachin A |
| aurachin b | An A-type aurachin that is quinoline N-oxide which is substituted by a methyl group at position 2, a hydroxy group at position 3, and a triprenyl group at position 4. | aurachin B |
| aurachin c | A C-type aurachin that is quinolin-4-one which is substituted by a hydroxy group at positions 1, a methyl group at position 2, and a triprenyl group at position 3. | aurachin C |
| aureothin | A C-nitro compound that is (3Z)-3-[(2E)-2-methyl-3-(4-nitrophenyl)prop-2-en-1-ylidene]tetrahydrofuran which is substituted by a 6-methoxy-3,5-dimethyl-4-oxo-4H-pyran-2-yl group at position 5. It is isolated from the soil bacterium, Streptomyces thioluteus and exhibits antitumor, antifungal, and insecticidal activities. | aureothin |
| aureothricin | A dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 4,5 and 6 have been replaced by methyl, oxo and propanoylamino groups, respectively. It is a moderate antimicrobial by-product of the thiolutin fermentation in various Streptomyces species. | aureothricin |
| avilamycin a | An oligosaccharide derivative that is produced by Streptomyces viridochromogenes and exhibits antibiotic properties. | avilamycin A |
| ay 25545 | A C-glycosylated naphthoisochromene derivative obtained from Streptomyces ravidus; exhibits antibiotic and anticancer properties. | ravidomycin |
| bacillaene | A polyene antibiotic obtained from Bacillus subtilis 168 that is active against a broad spectrum of bacteria. It is notoriously unstable. | bacillaene |
| bacillithiol | A thiol that is the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. | bacillithiol |
| bacterioruberin | A C50 carotenoid that is a red-coloured pigment found in several Halobacterium and Haloarcula species. | bacterioruberin |
| bafilomycin a1 | The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. | bafilomycin A1 |
| benzamidoxime | A member of the class of amidoximes obtained by formal condensation of the carbonyl group of benzamide with hydroxylamine. | benzamidoxime |
| benzylideneacetone | The trans-isomer of benzylideneacetone. It acts as an inhibitor of the enzyme phospholipase A2 (EC 3.1.1.4) of insects like diamond back moth. | trans-benzylideneacetone |
| beta-cyclocitral | A monoterpenoid formally derived from citral by cyclisation. It is a volatile compound produced by a cyanobacteria. | beta-cyclocitral |
| beta-hydroxymyristic acid | A 3-hydroxy fatty acid that is tetradecanoic (myristic) acid substituted at position 3 by a hydroxy group | 3-hydroxytetradecanoic acid |
| beta-lipotropin, gln(9)- | A crown compound that is enterobactin in which the pro-R hydrogens at positions 2, 6 and 10 of the trilactone backbone are replaced by methyl groups, and in which a glycine spacer separates the trilactone backbone from each of the catecholamide arms. It is the endogenous siderophore of Bacillus subtilis, used for the acquisition of iron. | corynebactin |
| beta-n-methylamino-l-alanine | A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens is replaced by a methylamino group. A non-proteinogenic amino acid produced by cyanobacteria, it is a neurotoxin that has been postulated as a possible cause of neurodegenerative disorders of aging such as Alzheimer's disease, amyotrophic lateral sclerosis, and the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS-PDC) syndrome of Guam. | L-BMAA |
| bialaphos | A tripeptide comprising one L-phosphinothricyl and two L-alanyl units joined in sequence. | bilanafos |
| bongkrekic acid | A tricarboxylic acid that is docosa-2,4,8,10,14,18,20-heptaenedioic acid substituted at positions 2 ,5 and 17 by methyl groups, at positions 6 by a methoxy group and at position 20 by a carboxymethyl group. It is produced by the bacterium Burkholderia gladioli and implicated in outbreaks of food-borne illness involving coconut and corn-based products in Indonesia and China. | bongkrekic acid |
| boromycin | A boron-containing macrolide antibiotic that is isolated from Streptomyces antibioticus. | boromycin |
| borrelidin | A macrolide that is isolated from several Streptomyces species and displays antibiotic, antineoplastic and antimalarial properties. | borrelidin |
| brasilicardin a | A diterpenoid antibiotic isolated from the culture broth of Nocardia brasiliensis IFM0406. It exhibits antitumour and strong immunosuppressive activity. | brasilicardin A |
| candicidin | A 38-membered ring lactone containing seven (E)-double bonds between positions 22 and 35 and substituted by hydroxy groups at positions 9, 11, 13, 17 and 19, oxo groups at positions 3, 7 and 15, a carboxy group at position 18, a 3-amino-3,6-dideoxymannopyranosyloxy group at position 21, a methyl group at position 36 and a 7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl group at position 37. It is the major component of candicidin, a mixture of antifungal heptaene macrolides obtained from a strain of Streptomyces griseus. | candicidin D |
| cembrene a | A fourteen-membered macrocyclic diterpene consisting of 1,5,9-trimethyl-12-(prop-1-en-2-yl)cyclotetradecane having three endocyclic double bonds located at positions 1, 5 and 9. | (R)-cembrene A |
| cerulomycin | A pyridine alkaloid that is 2,2'-bipyridine substituted by a methoxy group at position 4 and a (E)-(hydroxyimino)methyl group at position 6. Isolated from the marine-derived actinomycete Actinoalloteichus cyanogriseus, it exhibits antineoplastic activity. | caerulomycin A |
| chlorobactene | A carotenoid that is 1,2,4-trimethylmenzene in which the hydrogen at position 3 has been replaced by an all-trans-3,7,12,16,20,24-hexamethylpentacosa-1,3,5,7,9,11,13,15,17,19,23-undecaen-1-yl group. Found in photosynthetic green bacteria. | chlorobactene |
| chloroorienticin b | A glycopeptide that is isolated from Amycolatopsis orientalis. | chloroorienticin B |
| chondramide a | A chondramide that is chondramide C in which the pro-S hydrogen at position 2 of the beta-tyrosine residue is replaced by a methoxy group. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide A |
| chondramide c | A chondramide formally obtained from N-[(2S,4E,6R,7R)-7-hydroxy-2,4,6-trimethyloct-4-enoyl]-L-alanyl-Nalpha-methyl-D-tryptophanyl-beta-R-beta-tyrosine by intramolecular condensation of the alcoholic hydroxy group with the carboxy group of the beta-tyrosine residue. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide C |
| chondramide d | A chondramide that is chondramide C in which the hydrogen at position 2 of the indole moiety is replaced by a chlorine. It is produced by strains of the myxobacterium, Chondromyces crocatus. | chondramide D |
| chromopyrrolic acid | A pyrroledicarboxylic acid that is pyrrole-2,5-dicarboxylic acid in which the hydrogens at positions 3 and 4 have been replaced by indol-3-yl groups. | chromopyrrolic acid |
| chrysobactin | A catechol-type siderophore with a structure of D-lysyl-L-serine substituted on N(2) of the lysyl residue by a 2,3-dihydroxybenzoyl group. It is produced by the Gram-negative bacillus Dickeya dadantii (previously known as Erwinia chrysanthem). Only the catecholate hydroxyl groups participate in metal coordination, so chrysobactin cannot provide full 1:1 coordination of Fe(III); at neutral pH and concentrations of about 0.1 mM, ferric chrysobactin exists as a mixture of bis and tris complexes. | chrysobactin |
| chuangxinmycin | A thiinoindole that is 3,5-dihydro-2H-thiino[4,3,2-cd]indole which is substituted at positions 2 and 3 by carboxy and methyl groups, respectively (the 2R,3S diastereoisomer). | (-)-chuangxinmycin |
| ci 940 | A leptomycin having a (2E,10E,12E,16Z,18E)-double bond configuration as well as an ethyl substituent at position 17. | leptomycin B |
| clavulanic acid | Antibiotic isolated from Streptomyces clavuligerus. It acts as a suicide inhibitor of bacterial beta-lactamase enzymes. | clavulanic acid |
| coelichelin | A tetrapeptide hydroxamate siderophore that is isolated from Streptomyces coelicolor. | coelichelin |
| coumermycin | A hydroxycoumarin antibiotic that is obtained from Streptomyces rishiriensis and exhibits potent antibacterial and anticancer activity. | coumermycin A1 |
| cyanoginosin lr | A microcystin consisting of D-alanyl, L-leucyl, (3S)-3-methyl-D-beta-aspartyl,L-arginyl, 2S,3S,4E,6E,8S,9S)-3-amino-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyldecanoyl, D-gamma-glutamyl, and 2,3-didehydro-N-methylalanyl residues joined into a 25-membered macrocycle. Produced by the cyanobacterium Microcystis aeruginosa, it is the most studied of the microcystins. | microcystin-LR |
| cyclic 3',5'-uridine monophosphate | A 3',5'-cyclic pyrimidine nucleotide having uridine as the nucleobase. | 3',5'-cyclic UMP |
| cyclo(leucyl-prolyl) | A homodetic cyclic peptide composed from leucyl and prolyl residues. | cyclo(L-Leu-L-Pro) |
| cycloheximide | A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. | cycloheximide |
| cyclooctatin | A diterpenoid characterized by a 5-8-5 dodecahydrodicyclopenta[a,d]cyclooctene fused-ring system, with a single double bond and one isopropyl, two hydroxy, one hydroxymethyl and two methyl substituents. | cyclooctatin |
| cystothiazole a | An organonitrogen heterocyclic antibiotic that is 2,4'-bi-1,3-thiazole substituted by an isopropyl group at position 2' and a 3,5,7-trimethoxy-4-methyl-7-oxohepta-1,5-dien-1-yl group at position 4 (the 2E,4R,5S,6E stereoisomer). It is isolated from the culture broth of myxobacterium, Cystobacter fuscus, and exhibits antifungal and cytotoxic activity. | cystothiazole A |
| D-leucine | The D-enantiomer of leucine. | D-leucine zwitterion; D-leucine |
| D-tryptophan | The D-enantiomer of tryptophan. | D-tryptophan zwitterion; D-tryptophan |
| daunorubicin | A natural product found in Actinomadura roseola. | daunorubicin |
| decarbamylsaxitoxin | A pyrrolopurine that is 2,6-diiminodecahydropyrrolo[1,2-c]purine carrying an additional hydroxymethyl substituent at position 4 as well as two hydroxy substituents at position 10. A toxin that is isolated from marine dinoflagellates and cyanobacteria and is known to cause paralytic shellfish poisoning. | decarbamoylsaxitoxin |
| deferoxamine | An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator. | desferrioxamine B |
| deferrioxamine e | A cyclic hydroxamic acid siderophore that is produced by several bacterial species and exhibits antitumour activity. | desferrioxamine E |
| demycarosylturimycin h | A macrolide antibiotic produced by various Streptomyces species that is used to treat toxoplasmosis and various other infections of soft tissues. | spiramycin I |
| diazooxonorleucine | A non-proteinogenic L-alpha-amino acid that is L-norleucine which is substituted at position 5 by an oxo group and at position 6 by a diazo group. It is as inhibitor of various glutamine-utilising enzymes. | 6-diazo-5-oxo-L-norleucine zwitterion; 6-diazo-5-oxo-L-norleucine |
| dimethyldiselenide | An organoselenium compound that is diselane covalently bound to two methyl groups. It has been detected in onion-family vegetables and soft-necked garlics. It induces ER stress and toxic protein aggregation in the budding yeast, S. cerevisiae and used as a reagent to identify distonic radical cations. | dimethyl diselenide |
| dipicolinic acid | A pyridinedicarboxylic acid carrying two carboxy groups at positions 2 and 6. | dipicolinic acid |
| dodecanol | A primary alcohol that is dodecane in which a hydrogen from one of the methyl groups is replaced by a hydroxy group. It is registered for use in apple and pear orchards as a Lepidopteran pheromone/sex attractant, used to disrupt the mating behaviour of certain moths whose larvae destroy crops. | dodecan-1-ol |
| duramycin | A 19-membered heterodetic cyclic peptide that is isolated from Streptoverticillium cinnamoneus. It exhibits antiproliferative properties and induces apoptosis in tumour cells and has been used for treatment of cystic fibrosis. | lancovutide |
| echinenone | A carotenone that is beta-carotene in which the 4 position has undergone formal oxidation to afford the corresponding ketone. Isolated as orange-red crystals, it is widely distributed in marine invertebrates. | echinenone |
| elaiophylin | A macrodiolide that is isolated from several bacteria including Streptomyces violaceoniger and other soil actinomycetes. | elaiophylin |
| elloramycin | A member of the class of tetracenomycins that is 8-demethyltetracenomycin C in which the hydroxyl hydrogens at position 8 and 10 a are replaced by a 2,3,4-tri-O-methyl-alpha-L-rhamnosyl and methyl groups respectively. | elloramycin A |
| enterobactin | A macrotriolide produced by certain members of Enterobacteriaceae, e.g. Escherichia coli and Salmonella. | enterobactin |
| ephedrine | A phenethylamine alkaloid that is 2-phenylethanamine substituted by a methyl group at the amino nitrogen and a methyl and a hydroxy group at position 2 and 1 respectively. | (-)-ephedrine |
| filipin | A macrolide that is the major component of a mixture of four isomeric polyene macrolides isolated from Streptomyces filipinensis. | filipin III |
| flavin mononucleotide | A flavin mononucleotide that is riboflavin (vitamin B2) in which the primary hydroxy group has been converted to its dihydrogen phosphate ester. | FMN |
| fosmidomycin | Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. | fosmidomycin |
| fostriecin | A structurally unique, naturally-occurring phosphate monoester isolated from the soil bacterium Streptomyces pulveraceus. It inhibits DNA topoisomerase II as well as several protein phosphatase including PP2A and PPA4, and exhibits potent antitumor activity against several cancer cell lines. | fostriecin |
| fr 900848 | A polyketide that is 5'-amino-5'-deoxy-3,4,5,6-tetrahydrouridine in which one of the hydrogens of the amino group is substituted by a (1E,3E)-1-[(1R,1'R,1''R,1'''R,2S,2'R,2''R,2'''S)-2'''-{(E)-2-[(1R,2R)-2-methylcyclopropyl]ethenyl}[1,1':2',1'':2'',1'''-quater(cyclopropan)]-2-yl]-5-oxopenta-1,3-dien-5-yl group. It is a metabolite isolated from the bacterium, Streptoverticillium fervens and targets the catalytic subunit of the fungal UDP-glycosyltransferase, the first step in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors. It exhibits broad spectrum antifungal activity against several pathogenic fungi including Mucorales. | jawsamycin |
| fr 901464 | A spiro-epoxide with potent anticancer activity that lowers the mRNA levels of oncogenes and tumour supressor genes. It is isolated from Pseudomonas sp. no.2663. | FR901464 |
| furanomycin | A non-proteinogenic L-alpha-amino acid that is L-alanine in which the methyl group is replaced by a (2R,5S)-5-methyl-2,5-dihydrofuran-2-yl moiety. | furanomycin |
| gabaculine | The (S)-enantiomer of gabaculine. | (S)-gabaculine |
| gamma-dodecalactone | A gamma-lactone that is oxolan-2-one substituted by an octyl group at position 5. | gamma-dodecalactone |
| glucosaminic acid | Hexanoic acid with four hydroxy groups at C-3, C-4, C-5, C-6, and an amino group at C-2. | 2-amino-2-deoxy-D-gluconic acid zwitterion; 2-amino-2-deoxy-D-gluconic acid |
| glycocyamine | The N-amidino derivative of glycine. | guanidinoacetic acid zwitterion; guanidinoacetic acid |
| holomycin | A dithiolopyrrolone antibiotic that is 4,5-dihydro[1,2]dithiolo[4,3-b]pyrrole in which the hydrogens at positions 5 and 6 have been replaced by oxo and acetamido groups, respectively. It is an inhibitor of DNA-dependent RNA polymerase, and exhibits antibacterial and antitumour properties. | holomycin |
| indole-3-acetaldehyde | An indoleacetaldehyde that is acetaldehyde in which one of the methyl hydrogens are replaced by a indol-3-yl group. It is an intermediate metabolite in the metabolism of tryptophan. | indol-3-ylacetaldehyde |
| indole-3-carbaldehyde | A heteroarenecarbaldehyde that is indole in which the hydrogen at position 3 has been replaced by a formyl group. | indole-3-carbaldehyde |
| indole-3-carboxylic acid | An indole-3-carboxylic acid carrying a carboxy group at position 3. | indole-3-carboxylic acid |
| indoleacetamide | A member of the class of indoles that is acetamide substituted by a 1H-indol-3-yl group at position 2. It is an intermediate in the production of plant hormone indole acetic acid (IAA). | indole-3-acetamide |
| indolmycin | A member of the class of 1,3-oxazoles that is 1,3-oxazol-4(5H)-one which is substituted at the 2 and 5-pro-S positions by methylamino and [(1R)-1-(1H-indol-3-yl)ethyl] groups, respectively. | indolmycin |
| isoamylamine | A primary aliphatic amine that is butan-1-amine carrying a methyl substituent at position 3. | isopentylamine |
| jadomycin b | A jadomycin that is jadomycin A in which the phenolic hydroxy group at position 12 has been converted to the corresponding 2,6-dideoxy-alpha-L-ribo-hexopyranoside, isolated from Streptomyces venezuelae. It exists as a diastereoisomeric mixture consisting of both 3aS and 3aR isomers. | jadomycin B |
| kalimantacin a | A fatty acid derivative isolated from the fermentation broth of Alcaligenes sp. YL-02632S. It is an antibiotic with antibacterial activity. | kalimantacin B |
| kanamycin a | | kanamycin A |
| l 683590 | A macrolide that is produced by the fermentation of Streptomyces hygroscopicus and exhibits strong immunosuppressant properties. | ascomycin |
| lanosterol | A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. | lanosterol |
| lanthionine | An alanine derivative in which two alanine residues are linked on their beta-carbons by a thioether linkage. | lanthionine |
| lasalocid | A polyether antibiotic used for prevention and treatment of coccidiosis in poultry. | lasalocid |
| leupeptin | A tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death. | leupeptin |
| levodione | A member of the class of cyclohexanones that is cyclohexane-1,4-dionecarrying a gem-dimethyl group at position 2 and an additional methyl substituent at position 6 (the R-enantiomer). | levodione |
| lincomycin | A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis. | lincomycin |
| ly-146032 | A polypeptide comprising N-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, D-alanine, aspartic acid, glycine, D-serine, threo-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine with the alcohol group of the threonine residue. | daptomycin |
| mannostatin a | An amino cyclitol that is cyclopentane substituted by hydroxy groups at positions 1, 2 and 3, by an amino group at positon 4, and by a methylsulfanediyl group at position 5 (the 1R,2R,3R,4S,5R-stereoisomer). It is isolated from the soil bacterium Streptoverticillium verticillium. | mannostatin A |
| manumycin | A polyketide with formula C31H38N2O7 initially isolated from Streptomyces parvulus as a result of a random screening program for farnesyl transferase (FTase) inhibitors. It is a natural product that exhibits anticancer and antibiotic properties. | manumycin A |
| marinopyrrole a | A member of the class of pyrroles that is 1'H-1,3'-bipyrrole substituted by four chloro groups at positions 4, 4', 5 and 5' and two 2-hydroxybenzoyl moieties at positions 2 and 2'. It is isolated from Streptomyces sp.CNQ-418 and exhibits cytotoxic and antibacterial activities. | (-)-marinopyrrole A |
| marinoquinoline a | A pyrroloquinoline that is 3H-pyrrolo[2,3-c]quinoline substituted by a methyl group at position 4. It is a natural product found in Ohtaekwangia kribbensis and Rapidithrix thailandica. | marinoquinoline A |
| methane | A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC). | methane |
| methylethyl ketone | A dialkyl ketone that is a four-carbon ketone carrying a single keto- group at position C-2. | butan-2-one |
| methymycin | A twelve-membered macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. | methymycin |
| microcystin rr | | microcystin RR |
| microcystin-lf | A microcystin consisting of D-alanyl, L-leucyl, (3S)-3-methyl-D-beta-aspartyl, L-phenylalanyl, (2S,3S,4E,6E,8S,9S)-3-amino-4,5,6,7-tetradehydro-9-methoxy-2,6,8-trimethyl-10-phenyldecanoyl, D-gamma-glutamyl, and 2,3-didehydro-N-methylalanyl residues joined into a 25-membered macrocycle. | microcystin LF |
| mupirocin | An alpha,beta-unsaturated ester resulting from the formal condensation of the alcoholic hydroxy group of 9-hydroxynonanoic acid with the carboxy group of (2E)-4-[(2S)-tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoic acid in which the tetrahydropyranyl ring is substituted at positions 3 and 4 by hydroxy groups and at position 5 by a {(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl group. Originally isolated from the Gram-negative bacterium Pseudomonas fluorescens, it is used as a topical antibiotic for the treatment of Gram-positive bacterial infections. | mupirocin |
| myxochelin b | A member of the class of benzamides obtained by formal condensation of the 1- and 6-amino groups of hexane-1,2,6-triamine with the carboxy groups from two molecules of 2,3-dihydroxybenzoic acid followed by reduction of the amide carbonyl at position 5 to a hydroxy group. | myxochelin B |
| n-(3-oxododecanoyl)homoserine lactone | An N-acyl-L-homoserine lactone having 3-oxododecanoyl as the acyl substituent. | N-(3-oxododecanoyl)-L-homoserine lactone |
| n-acetylneuraminic acid | An N-acylneuraminic acid where the N-acyl group is specified as acetyl. | N-acetylneuraminic acid |
| n-acetyltyramine | A member of the class of tyramines that is tyramine in which one of the hydrogens of the amino group is replaced by an acetyl group. | N-acetyltyramine |
| nanaomycin a | A pyranonaphthoquinone antibiotic from strain OS-3966 of Streptomyces rosa var. notoensis. | nanaomycin A |
| narbomycin | A macrolide antibiotic that is narbonolide having a 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residue attached at position 6. It is biosynthesised by Streptomyces venezuelae. | narbomycin |
| natamycin | A macrolide antibiotic that has formula C33H47NO13, produced by several Streptomyces species including Streptomyces natalensis. It exhibits broad spectrum antifungal activity and used in eye drops, and as a food preservative, and also as a postharvest biofungicide for citrus and other fruit crops. | natamycin |
| neomethymycin | A twelve-membered macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. | neomethymycin |
| nigericin | A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. | nigericin |
| nitrous oxide | A nitrogen oxide consisting of linear unsymmetrical molecules with formula N2O. While it is the most used gaseous anaesthetic in the world, its major commercial use, due to its solubility under pressure in vegetable fats combined with its non-toxicity in low concentrations, is as an aerosol spray propellant and aerating agent for canisters of 'whipped' cream. | dinitrogen oxide |
| norvaline | A 2-aminopentanoic acid that has S-configuration. | L-2-aminopentanoic acid zwitterion; L-2-aminopentanoic acid |
| norvaline | An L-alpha-amino acid zwitterion obtained from L-2-aminopentanoic acid by transfer of a proton from the carboxy group to the amino group. It is the major species at pH 7.3. | L-2-aminopentanoic acid zwitterion; L-2-aminopentanoic acid |
| nucleocidin | A nucleoside antibiotic that is 5'-O-sulfamoyladenosine in which the hydrogen atom at position 4' is replaced by a fluorine atom. It is a natural product synthesized by several Streptomyces species. It exhibits broad spectrum antibacterial activity, and also has a strong effect against Trypanosoma brucei, the protozoan parasite responsible for the African sleeping sickness. | nucleocidin |
| octadecane | A straight-chain alkane carrying 18 carbon atoms. | octadecane |
| opt 80 | An 18-membered macrolide that is a fermentation product obtained from the Actinomycete Dactylosporangium aurantiacum. A narrow spectrum antibiotic used for treatment of Clostridium difficile-related infections. | fidaxomicin |
| orlistat | A carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug. | orlistat |
| orotidine | A nucleoside formed by attaching orotic acid to a ribose ring via a beta-N(1)-glycosidic bond. | orotidine |
| ossamycin | A macrolide antibiotic that was originally isolated from the culture broths of Streptomyces hygroscopicus var. ossamyceticus. | ossamycin |
| oxetanocin a | A nucleoside analogue found in Bacillus megaterium in which an adenine moiety is attached to position 2 of a of an oxetane ring which is substituted at positions 3 and 4 by hydroxymethyl groups. | oxetanocin A |
| pederin | A polyketide and carboxamide produced by a (Pseudomonas) bacterial endosymbiont of certain rove beetles (genus Paederus). Pederin is the agent responsible for the vesicant effects (linear or Paederus dermatitis) when the beetle is crushed against the skin. It is a powerful inhibitor of protein biosynthesis and mitosis and a potent antitumour agent. | pederin |
| pentalenolactone f | A tetracyclic sesquiterpene lactone obtained by formal epoxidation of the 4-methylene group of pentalenolactone E. | pentalenolactone F |
| pentostatin | A member of the class of coformycins that is coformycin in which the hydroxy group at position 2' is replaced with a hydrogen. It is a drug used for the treatment of hairy cell leukaemia. | pentostatin |
| pepstatin | A pentapeptide isolated from Streptomyces testaceus. It is a potent inhibitor of aspartyl proteases. | pepstatin A |
| phevalin | A member of the class of pyrazinones that is pyrazin-2(1H)-one substituted by an isopropyl and benzyl groups at position 3 and 6, respectively. It is a natural product found in Staphylococcus aureus that inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 muM), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression. | phevalin |
| phleomycin d1 | A glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. | phleomycin D1 |
| phosphoramidon | A dipeptide isolated from the cultures of Streptomyces tanashiensis. | phosphoramidon |
| picromycin | A macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. | pikromycin |
| piericidin a | A member of the class of monohydroxypyridines that acts as an irreversible mitochondrial Complex I inhibitor that strongly associates with ubiquinone binding sites in both mitochondrial and bacterial forms of NADH:ubiquinone oxidoreductase | piericidin A |
| platencin | A monocarboxylic acid amide obtained by the formal condensation of the amino group of 3-amino-2,4-dihydroxybenzoic acid with the carboxy group of the polycyclic cage component. It is an antibiotic isolated from Streptomyces platensis and exhibits inhibitory activity against fatty acid synthase. | platencin |
| platensimycin | A monocarboxylic acid amide obtained by the formal condensation of the amino group of 3-amino-2,4-dihydroxybenzoic acid with the carboxy group of the oxatetracyclic cage component. It is an antibiotic isolated from Streptomyces platensis and exhibits inhibitory activity against fatty acid synthase. | platensimycin |
| poly-o-acetylserine | An acetyl-L-serine where the acetyl group is attached to the side-chain oxygen. It is an intermediate in the biosynthesis of the amino acid cysteine in bacteria. | O-acetyl-L-serine zwitterion; O-acetyl-L-serine |
| pyocyanine | An iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group. An antibiotic pigment produced by Pseudomonas aeruginosa. | pyocyanine |
| pyoluteorin | A member of the class of resorcinols that is resorcinol in which the hydrogen at position 2 is replaced by a 4,5-dichloro-1H-pyrrole-2-carbonyl group. It is a natural product found in Pseudomonas fluorescens which exhibits antibacterial properties and is a strong inducer of caspase-3-dependent apoptosis. | pyoluteorin |
| pyrrolnitrin | A member of the class of pyrroles carrying chloro and 3-chloro-2-nitrophenyl substituents at positions 3 and 4 respectively. | pyrrolnitrin |
| pyrrolomycin a | A member of the class of pyrroles that is 1H-pyrrole which is substituted by chloro groups at positions 2 and 3 and by a nitro group position 4. It is the simplest member of the pyrrolomycins, a family of natural products found in several species of the Streptomyces genus. The compound is active against Gram-positive and Gram-negative bacteria and some genera of fungi. | pyrrolomycin A |
| quinolobactin | A quinolinemonocarboxylic acid that is xanthurenic acid in which the hydroxy group at position 4 is replaced by a methoxy group. It is a siderophore isolated from Pseudomonas fluorescens ATCC 17400. | quinolobactin |
| reumycin | A pyrimidotriazine that is 6-methyl-5,6,7,8-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 6. | reumycin |
| rhodopin | A carotenol having the structure of 1,2-dihydro-psi,psi-carotene with a hydroxy function at C-1. | rhodopin |
| rifamycin sv | A member of the class of rifamycins that exhibits antibiotic and antitubercular properties. | rifamycin SV |
| ristocetin | A heterodetic cyclic peptide that is produced by species of Amycolatopsis and Nocardia. | ristocetin |
| rosaramicin | A macrolide antibiotic with activity against Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis. | rosaramicin |
| roseoflavin | A benzopteridine that is riboflavin in which the methyl group at position 8 is substituted by a dimethylamino group. | roseoflavin |
| schizokinen | A hydroxamic acid resulting from the formal condensation of the primary amino group of N-(3-aminopropyl)-N-hydroxyacetamide (2 mol eq.) with the carboxy groups at positions 1 and 3 of citric acid. It is a siderophore produced by Bacillus megaterium and Anabaena species. | schizokinen |
| scytonemin | A ring assembly obtained by 1,1'-coupling of two molecules of (3E)-3-[(4-hydroxyphenyl)methylidene]cyclopenta[b]indol-2(3H)-one. A UV-screening molecule produced by many strains of cyanobacteria. | scytonemin |
| sf 2370 | A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a | K-252a |
| sibiromycin | An aminoglycoside antibiotic produced by Streptosporangium sibiricum that also exhibits antitumour properties. | sibiromycin |
| sirolimus | A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent. | sirolimus |
| soraphen a | A macrolide and an agent highly effective against plant-pathogenic fungi. It was extensively researched for agricultural use until it was discovered to be a teratogen. | soraphen A |
| spectinomycin | A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis. | spectinomycin |
| spheroidenone | The carotenone that is the 2-oxo derivative of (3E)-1-methoxy-3,4-didehydro-1,2,7',8'-tetrahydro-psi,psi-carotene. | spheroiden-2-one |
| spirilloxanthin | A carotenoid ether that is (3E,3'E)-1,1'-dihydroxy-3,3',4,4'-tetradehydro-1,1',2,2'-tetrahydro-psi,psi-carotene in which both hydroxyl hydrogens are replaced by methyl groups. | spirilloxanthin |
| spiruchostatin b | A spiruchostatin with molecular formula C21H33N3O6S2 originally isolated from a Pseudomonas culture broth. | spiruchostatin B |
| staphyloferrin a | A D-ornithine derivative obtained by formal condensation of the terminal carboxy groups of two citric acid units with the two amino groups of D-ornithine. | staphyloferrin A |
| staphyloferrin b | A siderophore composed from L-2,3-diaminopropionic acid, citric acid, 1,2-diaminoethane and alpha-ketoglutaric acid units. | staphyloferrin B |
| staurosporine | | staurosporine |
| stigmatellin | A member of the class of chromones that is isolated from Stigmatella aurantiaca Sg a15. | stigmatellin A |
| streptogramin b | A cyclodepsipeptide that is (together with pristinamycin IIA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus. | pristinamycin IA |
| streptolydigin | A monocarboxylic acid amide that is a broad-spectrum antibiotic produced by Streptomyces lydicus. | streptolydigin |
| streptomycin | A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class | streptomycin |
| sulfur | A homomonocyclic compound composed of eight sulfur atoms. It has been isolated from Ganoderma lucidum, a mushroom commonly used in Chinese medicine. | cyclooctasulfur |
| t-muurolol | A cadinane sesquiterpenoid that consists of 4-isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene having a hydroxy substituent at position 1 and (1S,4S,4aR,8aS)-configuration. | (-)-Tau-muurolol |
| tabtoxin | A monobactam phytotoxic dipeptide produced by Pseudomonas syringae, that causes wildfire disease in tobacco. | tabtoxin |
| tabtoxinine beta-lactam | | tabtoxinine beta-lactam |
| tacrolimus | A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. | tacrolimus (anhydrous) |
| tetradecanal | A long-chain fatty aldehyde that is tetradecane in which two hydrogens attached to a terminal carbon are replaced by an oxo group. It is found in coriander. | tetradecanal |
| tetramethylpyrazine | A member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii). | tetramethylpyrazine |
| tetrangulol | A member of the class of tetraphenes that is tetraphene-7,12-dione substituted by hydroxy groups at positions 1 and 8 and a methyl group at position 3. | tetrangulol |
| tetrodotoxin | A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels. | tetrodotoxin |
| thiazomycin | A heterodetic cyclic peptide isolated from Amycolatopsis fastidiosa. | thiazomycin |
| tilimycin | A pyrrolobenzodiazepine that is (11aS)-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine which is substituted by an oxo group at position 5 and by hydroxy groups at positions 9 and 11. It is an enterotoxic natural product synthesized via a non-ribosomal peptide synthase in Klebsiella oxytoca. | tilimycin |
| tilivalline | A pyrrolobenzodiazepine that is (11aS)-2,3,5,10,11,11a-hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine substituted by an oxo group at position 5, by a hydroxy group at position 9, and by a 1H-indol-3-yl group at position 11S. It is a natural product discovered in Klebsiella oxytoca which is the causative toxin in antibiotic associated hemorrhagic colitis. It exhibits a microtubule-stabilizing activity that leads to mitotic arrest in the host cells. | tilivalline |
| tmc-95a | A 17-membered macrocyclic lactam that incorporates a phenol and a substituted indole moiety. It includes a R-hydroxy group at position 11 and a (3-methyl-2-oxopentanoyl)amino group at position at position 18 with a S-methyl group. It acts as a proteasome inhibitor and is obtained from Apiospora montagnei Sacc. TC 1093, isolated from a soil sample. | TMC-95A |
| toxoflavin | A pyrimidotriazine that is 1,6-dimethyl-1,5,6,7-tetrahydropyrimido[5,4-e][1,2,4]triazine with oxo groups at positions 5 and 7. | toxoflavin |
| toyocamycin | An N-glycosylpyrrolopyrimidine that is tubercidin in which the hydrogen at position 5 of the pyrrolopyrimidine moiety has been replaced by a cyano group. | toyocamycin |
| triacsin c | A nitroso compound that is N-undecylnitrous hydrazide carrying double bonds at positions 1,2,4, and 7. It is a long-chain fatty acyl CoA synthetase inhibitor and interferes with lipid metabolism by inhibiting the de novo synthesis of glycerolipids and cholesterol esters. | triacsin C |
| trichostatin a | | trichostatin A |
| tropodithietic acid | A monocarboxylic acid that is 8,9-dithiabicyclo[5.2.0]nona-1,3,6-triene substituted by a carboxy group at position 2 and an oxo group at position 3. It is a broad spectrum antibiotic produced by the marine bacterium Phaeobacter inhibens that also acts as a signalling molecule at lower concentrations. | tropodithietic acid |
| tropolone | A cyclic ketone that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2. It is a toxin produced by the agricultural pathogen Burkholderia plantarii. | tropolone |
| tubercidin | An N-glycosylpyrrolopyrimidine that is adenosine in which the in the 5-membered ring that is not attached to the ribose moiety is replaced by a carbon. Tubercidin is produced in the culture broth of Streptomyces tubericidus. | tubercidin |
| turimycin | A macrolide antibiotic produced by Streptomyces kitasatoensis, showing activity against a wide spectrum of pathogens. | leucomycin V |
| tylosin | A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. It is found naturally as a fermentation product of Streptomyces fradiae. | tylosin |
| tyrocidine | A homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Phe, D-Phe, L-Asn, L-Gln, L-Tyr, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail. | tyrocidine A |
| u-47929 | | ficellomycin |
| undecylprodigiosin | A member of the class of tripyrroles that is 1H-pyrrole substituted by (4'-methoxy-1H,5'H-[2,2'-bipyrrol]-5'-ylidene)methyl and undecyl groups at positions 2 and 5, respectively. It is a pigment produced by Stveptomyces coelicolor. | undecylprodigiosin |
| validoxylamine a | An amino cyclitol that is (1R,2S,3S,4S,6R)-4-amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol in which one of the hydrogens attached to the nitrogen is replaced by a (1R,4R,5R,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl group. | validoxylamine A |
| valinomycin | A twelve-membered cyclodepsipeptide composed of three repeating D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains. | valinomycin |
| vanchrobactin | A catechol-type natural product that is composed of 2,3-dihydroxybenzoic acid, D-arginine and L-serine joined in sequence by peptide linkages. It is a siderophore synthesized by the bacterial fish pathogen Vibrio anguillarum. | vanchrobactin |
| vancomycin | A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. | vancomycin |
| vidarabine | A purine nucleoside in which adenine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. | adenine arabinoside |
| virginiamycin factor s1 | A cyclodepsipeptide that is N-(3-hydroxypicolinoyl)-L-threonyl-D-alpha-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the N-(3-hydroxypicolinoyl)-L-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. | virginiamycin S1 |
| xylobiose | A glycosylxylose that is D-xylopyranose having a beta-D-xylopyranosyl residue attached at position 4 via a glycosidic bond. | xylobiose |
| yersiniabactin | A member of the class of thiazolidines that is (4S)-4-methyl-4,5-dihydro-1,3-thiazole-4-carboxylic acid which is substituted at position 2 by a (1S)-1-hydroxy-1-{(4R)-2-[(4R)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazol-4-yl]-1,3-thiazolidin-4-yl}-2-methylpropan-2-yl group. A siderophore found in the gram-negative bacterium species, Yersinia enterocolitica and Yersinia pestis. | yersiniabactin |
| ym 216391 | An azamacrocycle with formula C34H32N8O7S isolated from the cultured mycelium of Streptomyces nobilis. It exhibits potent cytotoxic activity against human cancer cell lines. | YM-216391 |
| zeaxanthin | | zeaxanthin |
| zincophorin | | griseochelin |
| zorbamycin | A glycopeptide antibiotic found in Streptomyces flavoviridis. | zorbamycin |
| zwittermicin a | The (+)-enantiomer of zwittermicin A. It is a water-soluble natural antibiotic from the fermentation of the soil-borne bacterium Bacillus cereus and shows significant activity against phytopathogenic fungi. | (+)-zwittermicin A |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 20.4054 | 1 | 2 |
| 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase | Arabidopsis thaliana (thale cress) | Potency | 1.1873 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 6.1785 | 2 | 12 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 10.7346 | 4 | 7 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 35.5825 | 2 | 12 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Potency | 1.2589 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 33.9656 | 1 | 10 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 23.4451 | 1 | 2 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 17.0160 | 1 | 5 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 3.8610 | 1 | 2 |
| AR protein | Homo sapiens (human) | Potency | 22.9831 | 12 | 88 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 24.5932 | 3 | 13 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 7.5691 | 9 | 17 |
| Ataxin-2 | Homo sapiens (human) | Potency | 7.4008 | 1 | 6 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 8.1739 | 2 | 3 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 7.6878 | 2 | 10 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 16.9563 | 2 | 5 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 79.4328 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 28.7764 | 1 | 3 |
| Caspase-1 | Homo sapiens (human) | Potency | 2.3661 | 3 | 3 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 18.1318 | 2 | 3 |
| caspase-3 | Cricetulus griseus (Chinese hamster) | Potency | 32.7804 | 1 | 3 |
| caspase-3 | Homo sapiens (human) | Potency | 28.7764 | 1 | 3 |
| Caspase-7 | Cricetulus griseus (Chinese hamster) | Potency | 32.7804 | 1 | 3 |
| Caspase-7 | Homo sapiens (human) | Potency | 3.7636 | 3 | 3 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 38.3370 | 3 | 20 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 10.7058 | 2 | 5 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 19.2258 | 1 | 5 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 27.9006 | 1 | 6 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 23.2913 | 1 | 3 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 8.8645 | 3 | 5 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 33.2280 | 1 | 7 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 33.5972 | 2 | 5 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 20.1496 | 3 | 17 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 13.4769 | 3 | 6 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 36.9091 | 1 | 7 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 33.5972 | 2 | 5 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 76.5792 | 1 | 10 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 8.0500 | 2 | 2 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 20.8279 | 1 | 2 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 26.3524 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 22.1585 | 2 | 5 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 15.6928 | 2 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 28.2311 | 1 | 15 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 45.2688 | 1 | 2 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 3.0331 | 2 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 54.4028 | 2 | 6 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 13.2262 | 1 | 5 |
| dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Potency | 0.1000 | 1 | 1 |
| epidermal growth factor receptor isoform a precursor | Homo sapiens (human) | Potency | 0.1996 | 4 | 4 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 23.9967 | 10 | 89 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 19.0468 | 3 | 10 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 30.7292 | 6 | 47 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 12.2728 | 1 | 9 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 4.4290 | 4 | 9 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 418.0369 | 2 | 4 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 28.5398 | 5 | 10 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 4.4668 | 1 | 1 |
| Fumarate hydratase | Homo sapiens (human) | Potency | 0.0935 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 20.8279 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| galactokinase | Homo sapiens (human) | Potency | 1.1586 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 21.1069 | 1 | 3 |
| geminin | Homo sapiens (human) | Potency | 8.6543 | 2 | 24 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 22.3260 | 3 | 25 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 8.2649 | 1 | 5 |
| GLS protein | Homo sapiens (human) | Potency | 27.7170 | 1 | 2 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 15.1861 | 1 | 2 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 20.7039 | 5 | 29 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 22.9383 | 2 | 10 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 10.0000 | 1 | 1 |
| glyceraldehyde-3-phosphate dehydrogenase isoform 1 | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 28.6905 | 2 | 5 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 6.9241 | 1 | 2 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 42.8851 | 2 | 10 |
| hepatitis C virus polyprotein | | Potency | 7.0456 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 15.1861 | 1 | 4 |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | Potency | 3.9811 | 1 | 3 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 24.3095 | 1 | 6 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 48.7321 | 2 | 3 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 52.0432 | 2 | 14 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 19.0919 | 1 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 20.8279 | 1 | 2 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 12.9578 | 1 | 3 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 42.5693 | 2 | 9 |
| IDH1 | Homo sapiens (human) | Potency | 8.7038 | 1 | 10 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 20.8279 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 8.8006 | 1 | 2 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 8.3216 | 1 | 2 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 8.3216 | 1 | 2 |
| Interferon beta | Homo sapiens (human) | Potency | 2.9817 | 3 | 19 |
| interleukin 8 | Homo sapiens (human) | Potency | 62.1668 | 1 | 4 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 1.4204 | 1 | 4 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 12.9763 | 1 | 5 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 38.1689 | 2 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 0.0580 | 5 | 5 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 14.1838 | 2 | 14 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 15.8146 | 1 | 2 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 5.0119 | 1 | 1 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 6.1194 | 1 | 2 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 0.3335 | 3 | 3 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 7.8147 | 1 | 4 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 0.9296 | 1 | 2 |
| Nrf2 | Homo sapiens (human) | Potency | 3.5481 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 38.0995 | 4 | 30 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 7.7904 | 2 | 12 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 0.2951 | 1 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 39.2028 | 2 | 7 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 28.2357 | 1 | 4 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 6.2674 | 4 | 28 |
| nuclear receptor subfamily 1, group I, member 2 | Rattus norvegicus (Norway rat) | Potency | 15.8489 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 18.1517 | 3 | 19 |
| P53 | Homo sapiens (human) | Potency | 53.8083 | 1 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 44.9358 | 1 | 6 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 13.0051 | 1 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 7.6552 | 2 | 4 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 27.0563 | 5 | 17 |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 15.6596 | 4 | 11 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 1.2893 | 2 | 2 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 31.0975 | 1 | 7 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 5.4392 | 1 | 6 |
| Platelet-activating factor receptor | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| polyprotein | Zika virus | Potency | 0.0935 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 15.1861 | 1 | 2 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| PPM1D protein | Homo sapiens (human) | Potency | 0.7529 | 1 | 10 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 38.8152 | 3 | 9 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 59.6649 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 23.9649 | 3 | 12 |
| RAF proto-oncogene serine/threonine-protein kinase isoform b | Homo sapiens (human) | Potency | 0.1778 | 1 | 1 |
| Rap guanine nucleotide exchange factor 3 | Homo sapiens (human) | Potency | 54.5388 | 2 | 2 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 63.0957 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 17.3323 | 2 | 22 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 0.8534 | 1 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 18.9387 | 1 | 6 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 30.0694 | 3 | 42 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 15.2557 | 4 | 21 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 8.0500 | 2 | 2 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 0.8913 | 1 | 1 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 21.1923 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 54.7192 | 1 | 1 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 54.7192 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 7.2339 | 4 | 15 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 11.5953 | 2 | 7 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 2.6905 | 2 | 8 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 18.5283 | 1 | 7 |
| TDP1 protein | Homo sapiens (human) | Potency | 8.5395 | 2 | 43 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 56.2341 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 56.2452 | 2 | 4 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 23.0666 | 3 | 25 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 14.2071 | 4 | 10 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 15.6203 | 5 | 14 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 24.3896 | 2 | 4 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| TSHR protein | Homo sapiens (human) | Potency | 30.1313 | 1 | 1 |
| tumor necrosis factor | Homo sapiens (human) | Potency | 42.1632 | 1 | 1 |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | Potency | 0.1000 | 1 | 1 |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | Potency | 0.1000 | 1 | 1 |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | Potency | 0.1000 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 5.4392 | 1 | 6 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 5.4392 | 1 | 6 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 33.9394 | 2 | 9 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 13.2895 | 2 | 12 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 18.8259 | 4 | 9 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 51.0088 | 1 | 7 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 24.3759 | 1 | 9 |
| Vpr | Human immunodeficiency virus 1 | Potency | 3.1623 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial | Homo sapiens (human) | IC50 | 0.0005 | 2 | 2 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 231.6542 | 8 | 8 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycobacterium tuberculosis H37Rv | IC50 | 0.1650 | 6 | 6 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycolicibacterium smegmatis MC2 155 | IC50 | 0.2950 | 2 | 2 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycobacterium tuberculosis H37Rv | Ki | 0.1400 | 1 | 1 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Synechocystis sp. PCC 6803 substr. Kazusa | Ki | 0.0210 | 1 | 1 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli | IC50 | 0.4380 | 1 | 1 |
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplastic | Arabidopsis thaliana (thale cress) | IC50 | 0.1000 | 1 | 1 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 100.0000 | 2 | 4 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 2 |
| 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | Homo sapiens (human) | IC50 | 15.2000 | 1 | 1 |
| 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | Homo sapiens (human) | Ki | 15.2000 | 1 | 1 |
| 3-oxoacyl-[acyl-carrier-protein] synthase 2 | Staphylococcus aureus | IC50 | 4.5800 | 1 | 1 |
| 3-oxoacyl-[acyl-carrier-protein] synthase 3 | Escherichia coli K-12 | IC50 | 6.8000 | 1 | 2 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | IC50 | 0.0072 | 3 | 3 |
| 4-aminobutyrate aminotransferase, mitochondrial | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| 4-hydroxy-2-oxoglutarate aldolase, mitochondrial | Homo sapiens (human) | Ki | 11,000.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | IC50 | 4.0000 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | IC50 | 1.1060 | 1 | 1 |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | Ki | 0.7040 | 1 | 1 |
| 5-hydroxytryptamine receptor 3A | Cavia porcellus (domestic guinea pig) | IC50 | 7.6900 | 1 | 1 |
| 5'-AMP-activated protein kinase subunit beta-1 | Homo sapiens (human) | IC50 | 3.0363 | 1 | 5 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | IC50 | 3.0363 | 1 | 5 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 100.0000 | 2 | 4 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 100.0000 | 1 | 2 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 52.6000 | 3 | 3 |
| 90-kda heat shock protein beta HSP90 beta, partial | Homo sapiens (human) | IC50 | 1.0566 | 2 | 2 |
| Accessory gene regulator protein A | Staphylococcus aureus | IC50 | 6.0000 | 1 | 1 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 3.6000 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Actin | Saccharomyces cerevisiae S288C | IC50 | 13.9000 | 1 | 4 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | IC50 | 0.0298 | 2 | 2 |
| Activin receptor type-1 | Homo sapiens (human) | IC50 | 4.1977 | 2 | 6 |
| Activin receptor type-1B | Homo sapiens (human) | IC50 | 9.1180 | 1 | 1 |
| Acyl carrier protein, mitochondrial | Bos taurus (cattle) | IC50 | 0.0050 | 1 | 1 |
| Acyl-CoA desaturase 1 | Mus musculus (house mouse) | IC50 | 3.4000 | 1 | 1 |
| Acyl-protein thioesterase 1 | Rattus norvegicus (Norway rat) | IC50 | 110.0000 | 1 | 1 |
| Acyl-protein thioesterase 2 | Rattus norvegicus (Norway rat) | IC50 | 0.1700 | 1 | 1 |
| Adenomatous polyposis coli protein | Homo sapiens (human) | Ki | 118.0000 | 2 | 2 |
| Adenosine deaminase | Homo sapiens (human) | Ki | 0.0001 | 8 | 8 |
| Adenosine deaminase | Bos taurus (cattle) | Ki | 0.0000 | 2 | 3 |
| Adenosine deaminase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 0.0041 | 2 | 2 |
| Adenosine kinase | Homo sapiens (human) | IC50 | 1,292,888.1240 | 4 | 5 |
| Adenosine receptor A1 | Bos taurus (cattle) | IC50 | 0.1900 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | IC50 | 3,235,940.0000 | 1 | 1 |
| Adenosine receptor A1 | Sus scrofa (pig) | IC50 | 0.2000 | 1 | 1 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | IC50 | 3,235,940.0000 | 1 | 1 |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | IC50 | 3,235,940.0000 | 1 | 1 |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | IC50 | 3,235,940.0000 | 1 | 1 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 1.0800 | 1 | 1 |
| Adenosylhomocysteinase | Mus musculus (house mouse) | Ki | 30.0000 | 1 | 1 |
| Aldehyde oxidase | Homo sapiens (human) | IC50 | 0.0024 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | Sus scrofa (pig) | IC50 | 160.0000 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 0.0044 | 17 | 17 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 1.3000 | 1 | 1 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 1.0000 | 1 | 1 |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | Ki | 0.0501 | 1 | 1 |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.5629 | 2 | 2 |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.5629 | 2 | 2 |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | Ki | 0.5629 | 2 | 2 |
| Alpha-amylase | Geobacillus stearothermophilus | IC50 | 1.6700 | 1 | 1 |
| Alpha-galactosidase A | Homo sapiens (human) | Ki | 18.0000 | 1 | 1 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | IC50 | 278.0000 | 1 | 1 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | Ki | 18.0000 | 1 | 1 |
| Alpha-glucosidase MAL32 | Saccharomyces cerevisiae S288C | IC50 | 175.0000 | 1 | 2 |
| Alpha-glucosidase MAL62 | Saccharomyces cerevisiae (brewer's yeast) | IC50 | 212,855.0000 | 2 | 2 |
| Alpha-mannosidase | Canavalia ensiformis (jack bean) | Ki | 270.0000 | 1 | 1 |
| Alpha-mannosidase 2 | Drosophila melanogaster (fruit fly) | Ki | 0.0360 | 1 | 1 |
| Alpha-mannosidase 2 | Rattus norvegicus (Norway rat) | Ki | 50.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | IC50 | 0.0025 | 1 | 5 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 100.0000 | 1 | 1 |
| Angiopoietin-1 receptor | Homo sapiens (human) | IC50 | 9,916.7352 | 6 | 6 |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 100.0000 | 1 | 2 |
| Angiotensin-converting enzyme | Homo sapiens (human) | IC50 | 0.6150 | 2 | 2 |
| Apoptotic peptidase activating factor 1 | Homo sapiens (human) | IC50 | 57.7000 | 2 | 2 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 8 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 2.2250 | 2 | 2 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | Ki | 56.7500 | 2 | 2 |
| Aurora kinase A | Homo sapiens (human) | IC50 | 0.0084 | 23 | 23 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 8.3397 | 12 | 12 |
| Aurora kinase C | Homo sapiens (human) | IC50 | 0.0022 | 2 | 2 |
| Bcl-2-like protein 1 | Homo sapiens (human) | IC50 | 37.4167 | 4 | 6 |
| Bcl-2-like protein 11 | Homo sapiens (human) | IC50 | 13.4375 | 4 | 8 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | IC50 | 0.0004 | 3 | 3 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 49.7510 | 1 | 1 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | IC50 | 1.1595 | 2 | 2 |
| Beta-adrenergic receptor kinase 2 | Homo sapiens (human) | IC50 | 0.8560 | 2 | 2 |
| Beta-glucosidase | Agrobacterium tumefaciens | Ki | 12.0000 | 2 | 2 |
| Beta-glucosidase | Prunus avium (sweet cherry) | IC50 | 81.0000 | 1 | 1 |
| Beta-glucosidase A | Caldicellulosiruptor saccharolyticus | IC50 | 218.3333 | 3 | 3 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 118.1000 | 2 | 2 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 500.0075 | 2 | 2 |
| Beta-lactamase | Pseudomonas aeruginosa PAO1 | IC50 | 50.4000 | 2 | 2 |
| Beta-lactamase | Staphylococcus aureus | IC50 | 0.0800 | 1 | 1 |
| Beta-lactamase | Mycobacterium tuberculosis CDC1551 | Ki | 6.3000 | 1 | 1 |
| Beta-lactamase | Acinetobacter baumannii | IC50 | 1,850.0000 | 2 | 2 |
| Beta-lactamase | Acinetobacter pittii | IC50 | 1,208.6733 | 3 | 3 |
| Beta-lactamase | Citrobacter gillenii | IC50 | 0.0090 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 100.0000 | 1 | 1 |
| Beta-lactamase | Escherichia coli | IC50 | 127.1698 | 4 | 4 |
| Beta-lactamase | Klebsiella pneumoniae | IC50 | 0.8700 | 2 | 2 |
| Beta-lactamase | Pseudomonas aeruginosa | IC50 | 0.1000 | 3 | 3 |
| Beta-lactamase | Pseudomonas luteola | IC50 | 0.0360 | 1 | 1 |
| Beta-lactamase | Salmonella enterica subsp. enterica serovar Westhampton | IC50 | 0.0100 | 1 | 1 |
| Beta-lactamase | Serratia fonticola | IC50 | 72.8000 | 1 | 1 |
| Beta-lactamase | Shouchella clausii | IC50 | 0.0850 | 1 | 1 |
| Beta-lactamase class B VIM-2 | Pseudomonas aeruginosa | IC50 | 1.6600 | 1 | 1 |
| Beta-lactamase OXA-1 | Escherichia coli | IC50 | 3.2000 | 1 | 1 |
| Beta-lactamase SHV-1 | Escherichia coli | IC50 | 0.0280 | 1 | 1 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | IC50 | 0.1700 | 2 | 2 |
| Beta-lactamase SHV-1 | Klebsiella pneumoniae | Ki | 2.0000 | 1 | 1 |
| Beta-lactamase TEM | Escherichia coli | IC50 | 9.2560 | 5 | 5 |
| Beta-lactamase TEM | Escherichia coli | Ki | 0.8000 | 1 | 1 |
| Beta-lactamase VIM-1 | Pseudomonas aeruginosa | IC50 | 41.6000 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Leishmania major | IC50 | 2,000.0000 | 1 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | IC50 | 500.0000 | 1 | 1 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 237.8382 | 8 | 22 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | IC50 | 667.7000 | 1 | 3 |
| Bile salt export pump | Homo sapiens (human) | Ki | 31.0000 | 1 | 1 |
| Bile salt export pump | Rattus norvegicus (Norway rat) | Ki | 3.8000 | 1 | 1 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | IC50 | 4.2880 | 1 | 1 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | IC50 | 1.9400 | 2 | 2 |
| Breakpoint cluster region protein | Homo sapiens (human) | IC50 | 0.0945 | 4 | 4 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 44.0667 | 2 | 3 |
| Cadherin-1 | Homo sapiens (human) | Ki | 16.5000 | 2 | 2 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum K1 | IC50 | 0.2400 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | IC50 | 0.0359 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | IC50 | 0.0246 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1B | Homo sapiens (human) | IC50 | 0.0044 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | IC50 | 0.0046 | 2 | 2 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | IC50 | 0.0022 | 6 | 6 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 0.0590 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | IC50 | 0.0018 | 7 | 7 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | IC50 | 0.0024 | 5 | 5 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | IC50 | 0.0026 | 5 | 5 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | IC50 | 0.1475 | 2 | 2 |
| Calpain-1 catalytic subunit | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Calpain-1 catalytic subunit | Sus scrofa (pig) | IC50 | 0.0800 | 1 | 1 |
| cAMP-dependent protein kinase | Oryctolagus cuniculus (rabbit) | IC50 | 0.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit alpha | Bos taurus (cattle) | IC50 | 0.0887 | 5 | 17 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | IC50 | 0.0115 | 13 | 13 |
| cAMP-dependent protein kinase catalytic subunit alpha | Rattus norvegicus (Norway rat) | IC50 | 0.0550 | 3 | 3 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | IC50 | 0.0148 | 12 | 12 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | IC50 | 0.0137 | 11 | 11 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | IC50 | 0.0014 | 2 | 2 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 108.4250 | 1 | 8 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | Ki | 49.4000 | 1 | 1 |
| Candidapepsin-2 | Candida albicans | IC50 | 0.0900 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Cannabinoid receptor 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0100 | 1 | 1 |
| Cannabinoid receptor 1 | Homo sapiens (human) | Ki | 2.5000 | 1 | 1 |
| Cannabinoid receptor 2 | Homo sapiens (human) | Ki | 10.0000 | 1 | 1 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | IC50 | 10.5000 | 1 | 1 |
| Carbapenem-hydrolyzing beta-lactamase KPC | Klebsiella pneumoniae | Ki | 11.0000 | 1 | 1 |
| Carbonic anhydrase | Dicentrarchus labrax (European seabass) | Ki | 98.3000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 2.3700 | 1 | 1 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 3.5300 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 0.6000 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 3.1700 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 4.5300 | 1 | 1 |
| Carboxypeptidase A1 | Bos taurus (cattle) | IC50 | 2.7300 | 1 | 1 |
| Casein kinase I isoform alpha | Homo sapiens (human) | IC50 | 3.4120 | 4 | 4 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | IC50 | 1.8400 | 2 | 2 |
| Casein kinase I isoform delta | Homo sapiens (human) | IC50 | 1.4000 | 1 | 1 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | IC50 | 1.4000 | 1 | 1 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | IC50 | 5.3367 | 3 | 3 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | IC50 | 1.9467 | 3 | 3 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | IC50 | 2.6750 | 2 | 2 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 27.6042 | 4 | 4 |
| Casein kinase II subunit alpha | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 21.6172 | 5 | 5 |
| Casein kinase II subunit alpha' | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit alpha'-interacting protein | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 35.6000 | 3 | 3 |
| Casein kinase II subunit beta | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| caspase recruitment domain family, member 15 | Homo sapiens (human) | IC50 | 49.7510 | 1 | 1 |
| caspase-3 isoform a preproprotein | Homo sapiens (human) | IC50 | 11.4000 | 1 | 1 |
| caspase-9 isoform alpha precursor | Homo sapiens (human) | IC50 | 11.4000 | 1 | 1 |
| Catenin beta-1 | Homo sapiens (human) | IC50 | 82.9600 | 5 | 5 |
| Catenin beta-1 | Homo sapiens (human) | Ki | 4.7750 | 4 | 4 |
| Cathepsin B | Bos taurus (cattle) | IC50 | 0.3100 | 1 | 1 |
| Cathepsin B | Homo sapiens (human) | IC50 | 0.8820 | 5 | 5 |
| Cathepsin B | Homo sapiens (human) | Ki | 0.0063 | 3 | 3 |
| Cathepsin B | Capra hircus (goat) | Ki | 0.0063 | 2 | 2 |
| Cathepsin D | Homo sapiens (human) | IC50 | 5.8953 | 18 | 18 |
| Cathepsin D | Homo sapiens (human) | Ki | 0.0000 | 1 | 1 |
| Cathepsin D | Bos taurus (cattle) | IC50 | 0.0235 | 4 | 4 |
| Cathepsin D | Bos taurus (cattle) | Ki | 0.0005 | 1 | 1 |
| Cathepsin E | Homo sapiens (human) | IC50 | 0.5558 | 11 | 11 |
| Cathepsin K | Homo sapiens (human) | Ki | 0.0240 | 1 | 1 |
| cathepsin S isoform 1 preproprotein | Homo sapiens (human) | IC50 | 0.1765 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 8.1000 | 1 | 1 |
| CDK-activating kinase assembly factor MAT1 | Homo sapiens (human) | IC50 | 0.1216 | 4 | 4 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | IC50 | 0.0548 | 2 | 2 |
| Ceramide glucosyltransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | IC50 | 0.0027 | 5 | 5 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | IC50 | 0.0161 | 2 | 2 |
| Chain A, alpha-mannosidase II | Drosophila melanogaster (fruit fly) | Ki | 0.0360 | 1 | 2 |
| Chain A, CATHEPSIN D | Homo sapiens (human) | Ki | 0.0000 | 1 | 1 |
| Chain A, Cytochrome B | Paracoccus denitrificans PD1222 | IC50 | 0.1300 | 1 | 1 |
| Chain A, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | IC50 | 0.0150 | 1 | 2 |
| Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | Aquifex aeolicus | IC50 | 0.4000 | 1 | 1 |
| Chain A, Histone deacetylase 7a | Homo sapiens (human) | IC50 | 0.3000 | 1 | 2 |
| Chain A, Isoleucyl-tRNA synthetase | Thermus thermophilus | Ki | 0.2500 | 1 | 1 |
| Chain A, PLASMEPSIN II | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 0.0000 | 1 | 1 |
| Chain A, Protein kinase C, theta type | Homo sapiens (human) | Ki | 0.0003 | 1 | 1 |
| Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1 | Homo sapiens (human) | IC50 | 0.0100 | 1 | 2 |
| Chain A, PROTOCATECHUATE 3,4-DIOXYGENASE | Pseudomonas putida | Ki | 4,000.0000 | 1 | 6 |
| Chain A, Purine nucleoside phosphorylase | Escherichia coli | Ki | 120.0000 | 1 | 1 |
| Chain A, Purine nucleoside phosphorylase DeoD-type | Escherichia coli O157:H7 | Ki | 120.0000 | 1 | 1 |
| Chain A, Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Ki | 0.0078 | 1 | 3 |
| Chain A, Serine/threonine-protein kinase pknB | Mycobacterium tuberculosis | IC50 | 1.0000 | 1 | 1 |
| Chain A, Serine/threonine-protein kinase TAO2 | Rattus norvegicus (Norway rat) | IC50 | 3.0000 | 1 | 1 |
| Chain A, Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 0.0120 | 1 | 1 |
| Chain A, Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 0.0558 | 1 | 1 |
| Chain B, CATHEPSIN D | Homo sapiens (human) | Ki | 0.0000 | 1 | 1 |
| Chain B, Glycogen Synthase Kinase-3 Beta | Homo sapiens (human) | IC50 | 0.0150 | 1 | 1 |
| Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN) | Aquifex aeolicus | IC50 | 0.4000 | 1 | 1 |
| Chain C, DNA-directed RNA polymerase beta chain | Thermus thermophilus | Ki | 1.8000 | 1 | 1 |
| Chain D, DNA-directed RNA polymerase subunit beta' chain | Thermus thermophilus | Ki | 1.8000 | 1 | 1 |
| Chain E, Camp-dependent Protein Kinase | Bos taurus (cattle) | Ki | 0.0080 | 1 | 1 |
| Chain E, ENDOTHIAPEPSIN | Cryphonectria parasitica (chestnut blight fungus) | Ki | 0.0005 | 1 | 3 |
| Chain E, RHIZOPUSPEPSIN | Rhizopus microsporus var. chinensis | Ki | 0.0170 | 1 | 3 |
| Chain E, THERMOLYSIN | Bacillus thermoproteolyticus | Ki | 0.0280 | 1 | 2 |
| Chain F, Ubiquinol-cytochrome C Reductase Iron-sulfur Subunit | Paracoccus denitrificans PD1222 | IC50 | 0.1300 | 1 | 1 |
| Chain M, PROTOCATECHUATE 3,4-DIOXYGENASE | Pseudomonas putida | Ki | 4,000.0000 | 1 | 6 |
| Chain X, Proto-oncogene tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 0.0048 | 1 | 1 |
| Chymotrypsin-C | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Chymotrypsinogen A | Bos taurus (cattle) | Ki | 5,250.0000 | 1 | 4 |
| Citron Rho-interacting kinase | Homo sapiens (human) | IC50 | 0.7490 | 2 | 2 |
| Class D beta-lactamase | Brachyspira pilosicoli | IC50 | 2.0000 | 1 | 1 |
| Coagulation factor VII | Homo sapiens (human) | IC50 | 0.0340 | 1 | 1 |
| Coiled-coil domain-containing protein 6 | Homo sapiens (human) | IC50 | 0.0022 | 1 | 1 |
| Collagenase ColG | Hathewaya histolytica | IC50 | 46.8000 | 1 | 1 |
| COUP transcription factor 2 isoform a | Homo sapiens (human) | IC50 | 1.3150 | 1 | 1 |
| Cyclin-A1 | Homo sapiens (human) | IC50 | 0.0013 | 4 | 4 |
| Cyclin-A1 | Homo sapiens (human) | Ki | 0.0040 | 1 | 1 |
| Cyclin-A2 | Homo sapiens (human) | IC50 | 4.1749 | 12 | 12 |
| Cyclin-A2 | Homo sapiens (human) | Ki | 0.0026 | 2 | 3 |
| Cyclin-C | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 0.0075 | 23 | 23 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Ki | 0.0020 | 1 | 2 |
| Cyclin-dependent kinase 1 | Mus musculus (house mouse) | IC50 | 0.0080 | 1 | 1 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | IC50 | 0.0530 | 1 | 1 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | IC50 | 0.0570 | 1 | 1 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | IC50 | 0.1145 | 2 | 2 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | IC50 | 0.0206 | 2 | 2 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | IC50 | 0.0135 | 2 | 2 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | IC50 | 0.0587 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 1.5306 | 32 | 33 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Ki | 0.0026 | 2 | 3 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | IC50 | 0.0118 | 6 | 6 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 0.0575 | 13 | 14 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Ki | 0.0410 | 1 | 1 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 0.0141 | 9 | 9 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | IC50 | 0.0395 | 7 | 7 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | IC50 | 0.2793 | 5 | 5 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | IC50 | 0.0474 | 9 | 9 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Ki | 0.0070 | 1 | 1 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | IC50 | 1.1000 | 1 | 1 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 0.0141 | 9 | 9 |
| Cyclin-G-associated kinase | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Cyclin-H | Homo sapiens (human) | IC50 | 0.2793 | 5 | 5 |
| Cyclin-K | Homo sapiens (human) | IC50 | 0.0948 | 5 | 5 |
| Cyclin-O | Homo sapiens (human) | IC50 | 0.0015 | 4 | 4 |
| Cyclin-T1 | Homo sapiens (human) | IC50 | 0.0118 | 5 | 5 |
| Cyclin-T1 | Homo sapiens (human) | Ki | 0.0070 | 1 | 1 |
| Cyclin-T2 | Homo sapiens (human) | IC50 | 0.0038 | 1 | 1 |
| Cyclin-Y | Homo sapiens (human) | IC50 | 0.0518 | 8 | 8 |
| Cysteine protease | Leishmania donovani | IC50 | 0.0850 | 2 | 2 |
| Cysteine protease falcipain-3 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0925 | 2 | 2 |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0636 | 3 | 3 |
| Cytochrome P450 11B2, mitochondrial | Homo sapiens (human) | IC50 | 0.0110 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 85.6080 | 4 | 5 |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | IC50 | 5.2300 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | IC50 | 42.0750 | 2 | 2 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Ki | 11.0000 | 1 | 1 |
| Cytochrome P450 2B6 | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 25.1062 | 4 | 4 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 34.0093 | 3 | 3 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 33.3351 | 3 | 3 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 17.3600 | 5 | 6 |
| Cytochrome P450 3A5 | Homo sapiens (human) | IC50 | 0.3850 | 2 | 2 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | IC50 | 0.0046 | 2 | 2 |
| Cytosol aminopeptidase | Homo sapiens (human) | Ki | 50,000.0000 | 1 | 1 |
| Cytosolic beta-glucosidase | Homo sapiens (human) | IC50 | 160.0000 | 2 | 2 |
| D-alanyl-D-alanine dipeptidase | Enterococcus faecium | Ki | 62.0000 | 1 | 1 |
| D(1A) dopamine receptor | Sus scrofa (pig) | IC50 | 0.0010 | 1 | 1 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 0.0101 | 6 | 6 |
| Death-associated protein kinase 2 | Homo sapiens (human) | IC50 | 0.0064 | 2 | 2 |
| Death-associated protein kinase 3 | Homo sapiens (human) | IC50 | 0.0026 | 2 | 2 |
| Delta-type opioid receptor | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Deoxyhypusine hydroxylase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Diacylglycerol lipase-alpha | Homo sapiens (human) | IC50 | 0.2678 | 4 | 4 |
| Diacylglycerol lipase-alpha | Mus musculus (house mouse) | IC50 | 0.0200 | 1 | 1 |
| Diacylglycerol lipase-beta | Homo sapiens (human) | IC50 | 0.2400 | 2 | 2 |
| Dihydrofolate reductase | Homo sapiens (human) | IC50 | 325.0000 | 1 | 1 |
| Dihydrofolate reductase | Homo sapiens (human) | Ki | 880.0000 | 1 | 1 |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 0.0620 | 1 | 1 |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | IC50 | 0.0030 | 1 | 1 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | IC50 | 0.0008 | 2 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 9 | Homo sapiens (human) | IC50 | 0.0563 | 1 | 1 |
| DNA (cytosine-5)-methyltransferase 3B | Homo sapiens (human) | IC50 | 0.8075 | 4 | 4 |
| DNA-directed RNA polymerase subunit beta | Escherichia coli K-12 | IC50 | 50.0100 | 1 | 5 |
| DNA-directed RNA polymerase subunit beta | Shigella sonnei Ss046 | IC50 | 50.0100 | 1 | 5 |
| Dopamine beta-hydroxylase | Homo sapiens (human) | IC50 | 2.5000 | 1 | 2 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | IC50 | 0.0552 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 0.2314 | 12 | 12 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | IC50 | 0.0260 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | IC50 | 0.0099 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | IC50 | 0.8630 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | IC50 | 0.0252 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | IC50 | 0.0036 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | IC50 | 0.9255 | 2 | 2 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | IC50 | 0.0108 | 2 | 2 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | IC50 | 1.8994 | 4 | 8 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | IC50 | 0.9200 | 2 | 2 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | IC50 | 0.0723 | 2 | 2 |
| dual specificity protein phosphatase 3 | Homo sapiens (human) | IC50 | 1.1700 | 2 | 2 |
| dual specificity protein phosphatase 6 | Rattus norvegicus (Norway rat) | IC50 | 2.3200 | 1 | 1 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | IC50 | 0.1995 | 2 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | IC50 | 0.0095 | 4 | 4 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Rattus norvegicus (Norway rat) | IC50 | 0.0120 | 1 | 1 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | IC50 | 0.0017 | 3 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | IC50 | 0.1800 | 2 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 3 | Homo sapiens (human) | IC50 | 0.0231 | 2 | 2 |
| EEF1AKMT4-ECE2 readthrough transcript protein | Homo sapiens (human) | Ki | 0.0012 | 1 | 1 |
| Endothelial lipase | Homo sapiens (human) | IC50 | 0.0060 | 1 | 1 |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | IC50 | 0.0360 | 1 | 1 |
| Endothelin-converting enzyme 1 | Homo sapiens (human) | IC50 | 1.0695 | 6 | 6 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | IC50 | 0.0947 | 3 | 3 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | IC50 | 0.1257 | 3 | 3 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | IC50 | 0.0347 | 4 | 4 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | IC50 | 0.0159 | 2 | 2 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | IC50 | 0.0160 | 2 | 2 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | IC50 | 0.0478 | 2 | 2 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | IC50 | 0.1061 | 2 | 2 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | IC50 | 0.0694 | 3 | 3 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | IC50 | 0.1191 | 3 | 3 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | IC50 | 1.2855 | 2 | 2 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | IC50 | 0.1869 | 4 | 4 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 5.4744 | 33 | 33 |
| Epidermal growth factor receptor | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| epidermal growth factor receptor isoform a precursor | Homo sapiens (human) | IC50 | 0.4467 | 1 | 1 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | IC50 | 0.9655 | 3 | 3 |
| Eukaryotic initiation factor 4A-I | Homo sapiens (human) | IC50 | 0.1390 | 4 | 4 |
| exodeoxyribonuclease V subunit RecB | Escherichia coli str. K-12 substr. MG1655 | IC50 | 118.5750 | 1 | 1 |
| exodeoxyribonuclease V subunit RecC | Escherichia coli str. K-12 substr. MG1655 | IC50 | 118.5750 | 1 | 1 |
| exodeoxyribonuclease V subunit RecD | Escherichia coli str. K-12 substr. MG1655 | IC50 | 118.5750 | 1 | 1 |
| Exportin-1 | Homo sapiens (human) | IC50 | 0.0760 | 2 | 2 |
| Fatty acid synthase | Homo sapiens (human) | IC50 | 69.6600 | 3 | 3 |
| Fatty acid synthase | Homo sapiens (human) | Ki | 0.2800 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | IC50 | 0.0100 | 1 | 1 |
| Fibrinogen C domain-containing protein 1 | Homo sapiens (human) | IC50 | 4,000.0000 | 1 | 1 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | IC50 | 0.0699 | 7 | 7 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | IC50 | 0.0504 | 10 | 10 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | IC50 | 0.0554 | 10 | 10 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | IC50 | 13,900.1457 | 7 | 7 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 0.0780 | 10 | 10 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | IC50 | 0.0914 | 2 | 2 |
| G protein-coupled receptor kinase 5 | Homo sapiens (human) | IC50 | 0.0490 | 2 | 2 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | IC50 | 11.3649 | 3 | 3 |
| G-protein coupled receptor 84 | Homo sapiens (human) | Ki | 0.5110 | 1 | 1 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | IC50 | 0.0501 | 14 | 15 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | Ki | 0.0410 | 1 | 1 |
| G1/S-specific cyclin-D3 | Homo sapiens (human) | IC50 | 0.0550 | 6 | 6 |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | IC50 | 0.0249 | 18 | 19 |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | IC50 | 0.0110 | 3 | 3 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 0.0088 | 14 | 14 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | IC50 | 0.0107 | 5 | 5 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | IC50 | 0.0107 | 5 | 5 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | Ki | 3.1000 | 1 | 1 |
| Gag-Pro polyprotein | Human T-cell lymphotrophic virus type 1 (strain ATK) | Ki | 25.5500 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 2.1000 | 1 | 1 |
| Gap junction alpha-1 protein | Homo sapiens (human) | IC50 | 48.0000 | 1 | 1 |
| Gap junction beta-2 protein | Homo sapiens (human) | IC50 | 10.4500 | 2 | 2 |
| Glucose transporter | Leishmania mexicana | IC50 | 0.2335 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 0.0480 | 1 | 1 |
| Glycogen debranching enzyme | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Glycogen debranching enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 0.1900 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 0.0103 | 5 | 5 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 0.0435 | 40 | 40 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Ki | 0.0220 | 1 | 1 |
| green fluorescent protein, partial | Aequorea victoria | IC50 | 67.5490 | 1 | 2 |
| GTPase KRas | Homo sapiens (human) | IC50 | 3.5800 | 1 | 1 |
| HD2 type histone deacetylase HDA106 | Zea mays | IC50 | 0.0060 | 11 | 11 |
| HD2 type histone deacetylase HDA106 | Zea mays | Ki | 0.0044 | 2 | 2 |
| heat shock protein HSP 90-alpha isoform 2 | Homo sapiens (human) | IC50 | 1.0566 | 2 | 2 |
| Hepatic triacylglycerol lipase | Homo sapiens (human) | IC50 | 0.0030 | 1 | 1 |
| Hepatocyte growth factor activator | Homo sapiens (human) | Ki | 0.1880 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 0.1917 | 17 | 17 |
| Hexokinase-4 | Homo sapiens (human) | IC50 | 0.0006 | 2 | 2 |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.3180 | 1 | 2 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | IC50 | 91.0646 | 11 | 11 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | IC50 | 0.1000 | 1 | 2 |
| Histone deacetylase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0006 | 1 | 1 |
| Histone deacetylase | Rattus norvegicus (Norway rat) | IC50 | 0.1854 | 8 | 18 |
| Histone deacetylase | Zea mays | IC50 | 0.0004 | 2 | 2 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 0.4164 | 115 | 135 |
| Histone deacetylase 1 | Mus musculus (house mouse) | IC50 | 0.0043 | 7 | 7 |
| Histone deacetylase 1 | Rattus norvegicus (Norway rat) | IC50 | 0.1854 | 8 | 9 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 0.0723 | 7 | 7 |
| Histone deacetylase 1 | Mus musculus (house mouse) | Ki | 0.0011 | 1 | 1 |
| Histone deacetylase 11 | Mus musculus (house mouse) | IC50 | 0.0014 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 0.6989 | 42 | 53 |
| Histone deacetylase 11 | Homo sapiens (human) | Ki | 0.4525 | 2 | 2 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 0.6401 | 67 | 87 |
| Histone deacetylase 2 | Mus musculus (house mouse) | IC50 | 0.0014 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 0.0851 | 6 | 6 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 0.3388 | 60 | 80 |
| Histone deacetylase 3 | Mus musculus (house mouse) | IC50 | 0.0014 | 1 | 1 |
| Histone deacetylase 3 | Rattus norvegicus (Norway rat) | IC50 | 0.1854 | 8 | 9 |
| Histone deacetylase 3 | Homo sapiens (human) | Ki | 0.0844 | 6 | 6 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 0.8552 | 54 | 74 |
| Histone deacetylase 4 | Mus musculus (house mouse) | IC50 | 0.0014 | 1 | 1 |
| Histone deacetylase 4 | Rattus norvegicus (Norway rat) | IC50 | 0.1854 | 8 | 9 |
| Histone deacetylase 4 | Homo sapiens (human) | Ki | 3.6502 | 5 | 5 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 0.5332 | 38 | 58 |
| Histone deacetylase 5 | Mus musculus (house mouse) | IC50 | 0.0107 | 2 | 2 |
| Histone deacetylase 5 | Homo sapiens (human) | Ki | 1.2860 | 4 | 4 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 0.2540 | 101 | 121 |
| Histone deacetylase 6 | Mus musculus (house mouse) | IC50 | 0.0387 | 7 | 7 |
| Histone deacetylase 6 | Homo sapiens (human) | Ki | 0.0730 | 7 | 7 |
| Histone deacetylase 6 | Rattus norvegicus (Norway rat) | IC50 | 0.1854 | 8 | 9 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 0.5052 | 37 | 57 |
| Histone deacetylase 7 | Mus musculus (house mouse) | IC50 | 0.0014 | 1 | 1 |
| Histone deacetylase 7 | Rattus norvegicus (Norway rat) | IC50 | 0.1854 | 8 | 9 |
| Histone deacetylase 7 | Homo sapiens (human) | Ki | 0.2980 | 3 | 3 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 1.2855 | 72 | 92 |
| Histone deacetylase 8 | Mus musculus (house mouse) | IC50 | 0.0207 | 2 | 2 |
| Histone deacetylase 8 | Schistosoma mansoni | IC50 | 3.6200 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 0.1405 | 7 | 7 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 0.5704 | 37 | 57 |
| Histone deacetylase 9 | Mus musculus (house mouse) | IC50 | 0.0014 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | Ki | 0.7013 | 3 | 3 |
| Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | IC50 | 1.2000 | 1 | 1 |
| Histone deacetylase-like amidohydrolase | Alcaligenaceae bacterium FB188 | Ki | 0.7000 | 1 | 1 |
| Histone-lysine N-methyltransferase, H3 lysine-79 specific | Homo sapiens (human) | IC50 | 44.0000 | 1 | 1 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | IC50 | 2.6390 | 1 | 1 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | IC50 | 0.3655 | 2 | 2 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | IC50 | 0.4560 | 2 | 2 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | IC50 | 0.2260 | 2 | 2 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | IC50 | 0.0360 | 1 | 1 |
| Inactive tyrosine-protein kinase PEAK1 | Homo sapiens (human) | IC50 | 0.0025 | 2 | 2 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 10.7500 | 2 | 4 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 0.0101 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 homolog | Mus musculus (house mouse) | IC50 | 10.1000 | 3 | 3 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | IC50 | 0.1265 | 5 | 5 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 0.5561 | 9 | 9 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | IC50 | 22.7000 | 1 | 1 |
| Insulin receptor | Homo sapiens (human) | IC50 | 0.0706 | 6 | 6 |
| Insulin receptor | Mus musculus (house mouse) | IC50 | 0.2000 | 1 | 1 |
| Insulin receptor-related protein | Homo sapiens (human) | IC50 | 0.0113 | 2 | 2 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 0.5534 | 13 | 13 |
| Integrin alpha-IIb | Homo sapiens (human) | IC50 | 0.0263 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | IC50 | 0.0263 | 1 | 1 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | IC50 | 0.0377 | 2 | 2 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | IC50 | 0.0122 | 4 | 4 |
| Isoleucine--tRNA ligase | Escherichia coli K-12 | Ki | 0.0025 | 1 | 1 |
| Kappa-type opioid receptor | Mus musculus (house mouse) | IC50 | 0.1903 | 1 | 2 |
| Kinase suppressor of Ras 1 | Homo sapiens (human) | IC50 | 6.2650 | 2 | 2 |
| Kinase suppressor of Ras 2 | Homo sapiens (human) | IC50 | 5.4000 | 2 | 2 |
| Kinesin-1 heavy chain | Homo sapiens (human) | IC50 | 0.0015 | 1 | 1 |
| L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase | Mycobacterium tuberculosis H37Rv | IC50 | 5,000.0000 | 1 | 1 |
| Lactase-phlorizin hydrolase | Homo sapiens (human) | IC50 | 62.0000 | 1 | 1 |
| Lactase-phlorizin hydrolase | Rattus norvegicus (Norway rat) | IC50 | 36.3333 | 3 | 3 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 2 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0076 | 3 | 3 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | IC50 | 0.0173 | 3 | 3 |
| Leukotriene A-4 hydrolase | Homo sapiens (human) | IC50 | 10.0000 | 2 | 2 |
| LIM domain kinase 1 | Homo sapiens (human) | IC50 | 0.0026 | 2 | 2 |
| LIM domain kinase 2 | Homo sapiens (human) | IC50 | 0.0956 | 2 | 2 |
| Lipoprotein lipase | Homo sapiens (human) | IC50 | 0.0660 | 1 | 1 |
| Lymphokine-activated killer T-cell-originated protein kinase | Homo sapiens (human) | IC50 | 0.0691 | 2 | 2 |
| Lysine--tRNA ligase | Homo sapiens (human) | IC50 | 0.0049 | 2 | 2 |
| Lysine-specific demethylase 4A | Homo sapiens (human) | IC50 | 2.8875 | 4 | 4 |
| Lysine-specific demethylase 4C | Homo sapiens (human) | IC50 | 0.5205 | 2 | 2 |
| Lysine-specific demethylase 4E | Homo sapiens (human) | IC50 | 74.2000 | 2 | 2 |
| Lysophosphatidylserine lipase ABHD12 | Homo sapiens (human) | IC50 | 0.1682 | 3 | 5 |
| Lysosomal acid glucosylceramidase | Bos taurus (cattle) | IC50 | 210.0000 | 1 | 1 |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | IC50 | 280.3333 | 6 | 6 |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | Ki | 68.3333 | 3 | 3 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 39.2600 | 6 | 6 |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | IC50 | 0.3125 | 4 | 4 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | Ki | 12.5295 | 2 | 2 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | IC50 | 0.1269 | 7 | 9 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | IC50 | 0.2195 | 5 | 5 |
| Maltase-glucoamylase, intestinal | Homo sapiens (human) | IC50 | 34.7614 | 7 | 7 |
| Mannosyl-oligosaccharide alpha-1,2-mannosidase IA | Drosophila melanogaster (fruit fly) | IC50 | 0.1500 | 1 | 1 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | IC50 | 0.7350 | 10 | 10 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | IC50 | 2.7750 | 2 | 2 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | IC50 | 0.2120 | 2 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.0530 | 2 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0221 | 3 | 3 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | IC50 | 0.0004 | 2 | 2 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | IC50 | 0.0375 | 11 | 11 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | IC50 | 0.0006 | 2 | 2 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | IC50 | 0.4420 | 2 | 2 |
| Metallo-beta-lactamase L1 type 3 | Stenotrophomonas maltophilia | IC50 | 7.8000 | 1 | 1 |
| Metallo-beta-lactamase type 2 | Bacillus cereus | IC50 | 21.8000 | 1 | 1 |
| Metallo-beta-lactamase type 2 | Serratia marcescens | IC50 | 3.0300 | 1 | 1 |
| Metallo-beta-lactamase VIM-13 | Pseudomonas aeruginosa | IC50 | 48.0000 | 1 | 1 |
| Methylcytosine dioxygenase TET2 | Homo sapiens (human) | IC50 | 46.0000 | 1 | 1 |
| Misshapen-like kinase 1 | Homo sapiens (human) | IC50 | 0.0004 | 4 | 4 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | IC50 | 5.5321 | 11 | 11 |
| Mitogen-activated protein kinase 1 | Mus musculus (house mouse) | IC50 | 10.0000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 0.0731 | 1 | 1 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | IC50 | 0.4512 | 3 | 3 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | IC50 | 0.4137 | 3 | 3 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 0.5052 | 2 | 2 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | IC50 | 0.0081 | 3 | 3 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | IC50 | 9.0475 | 11 | 11 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | IC50 | 5.9524 | 4 | 4 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | IC50 | 1.1067 | 6 | 6 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | IC50 | 2.0555 | 4 | 4 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | IC50 | 0.4380 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | IC50 | 0.1109 | 4 | 6 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | IC50 | 0.0213 | 4 | 6 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | IC50 | 0.0992 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 14 | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | IC50 | 0.0087 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | IC50 | 0.0335 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 21 | Homo sapiens (human) | IC50 | 1.1175 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | IC50 | 0.0092 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | IC50 | 0.2150 | 5 | 5 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | IC50 | 0.2829 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | IC50 | 0.0565 | 5 | 5 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | IC50 | 0.0155 | 4 | 6 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | IC50 | 0.0005 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | IC50 | 0.0002 | 2 | 2 |
| MO15-related protein kinase Pfmrk | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 4.0000 | 2 | 2 |
| Monoacylglycerol lipase ABHD6 | Homo sapiens (human) | IC50 | 0.0300 | 5 | 6 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 0.5100 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 121.1125 | 1 | 8 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | IC50 | 0.1161 | 3 | 3 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | IC50 | 0.0147 | 2 | 2 |
| Myosin light chain kinase 3 | Homo sapiens (human) | IC50 | 0.1585 | 2 | 2 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | IC50 | 0.0537 | 2 | 2 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | IC50 | 0.0000 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | IC50 | 0.0391 | 4 | 4 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Ki | 0.0200 | 1 | 1 |
| Myosin-IIIa | Homo sapiens (human) | IC50 | 0.0425 | 2 | 2 |
| Myosin-IIIb | Homo sapiens (human) | IC50 | 0.0058 | 2 | 2 |
| Myotonin-protein kinase | Homo sapiens (human) | IC50 | 0.1735 | 2 | 2 |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | IC50 | 0.8700 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | IC50 | 14.4000 | 1 | 1 |
| NAD-dependent protein deacetylase sirtuin-6 | Homo sapiens (human) | Ki | 226.0000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | Bos taurus (cattle) | IC50 | 0.0050 | 1 | 1 |
| NADH-ubiquinone oxidoreductase chain 1 | Bos taurus (cattle) | IC50 | 0.0045 | 2 | 2 |
| NADPH oxidase 4 | Homo sapiens (human) | IC50 | 0.0708 | 1 | 1 |
| Neprilysin | Homo sapiens (human) | IC50 | 0.0405 | 4 | 4 |
| Neprilysin | Oryctolagus cuniculus (rabbit) | IC50 | 0.0028 | 3 | 3 |
| Neprilysin | Rattus norvegicus (Norway rat) | IC50 | 0.0578 | 6 | 6 |
| Neprilysin | Rattus norvegicus (Norway rat) | Ki | 0.0040 | 1 | 1 |
| Neutral alpha-glucosidase AB | Homo sapiens (human) | IC50 | 472.8250 | 3 | 4 |
| Neutral alpha-glucosidase AB | Homo sapiens (human) | Ki | 410.0000 | 1 | 1 |
| Neutral cholesterol ester hydrolase 1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Non-lysosomal glucosylceramidase | Homo sapiens (human) | IC50 | 24.9500 | 4 | 4 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | IC50 | 0.0012 | 2 | 2 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | IC50 | 0.0137 | 5 | 5 |
| NT-3 growth factor receptor | Homo sapiens (human) | IC50 | 0.0002 | 2 | 2 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 0.0030 | 4 | 4 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | IC50 | 0.0018 | 2 | 2 |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | IC50 | 0.0138 | 7 | 7 |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | Ki | 0.0006 | 2 | 2 |
| nuclear receptor corepressor 2 isoform 2 | Homo sapiens (human) | IC50 | 39.8410 | 1 | 1 |
| Oligo-1,6-glucosidase IMA1 | Saccharomyces cerevisiae S288C | IC50 | 330.0000 | 1 | 1 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | IC50 | 137.5000 | 3 | 4 |
| Oxysterols receptor LXR-beta | Homo sapiens (human) | IC50 | 150.0000 | 2 | 3 |
| P2X purinoceptor 3 | Homo sapiens (human) | IC50 | 0.7550 | 1 | 1 |
| P2Y purinoceptor 12 | Homo sapiens (human) | IC50 | 0.0170 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Homo sapiens (human) | IC50 | 0.3253 | 3 | 3 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 0.4214 | 14 | 14 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | Ki | 5.0300 | 2 | 2 |
| Papain | Carica papaya (papaya) | IC50 | 0.0022 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.0107 | 2 | 2 |
| Pepsin A | Sus scrofa (pig) | IC50 | 0.0110 | 5 | 5 |
| Pepsin A | Sus scrofa (pig) | Ki | 0.0000 | 2 | 2 |
| Pepsin A-5 | Homo sapiens (human) | IC50 | 0.0590 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP14 | Homo sapiens (human) | Ki | 76.2000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | IC50 | 3.0670 | 11 | 14 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | IC50 | 0.0010 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | Ki | 1.4670 | 5 | 6 |
| Peptidyl-prolyl cis-trans isomerase FKBP3 | Homo sapiens (human) | Ki | 124.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP4 | Homo sapiens (human) | IC50 | 8.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP4 | Homo sapiens (human) | Ki | 24.2000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP5 | Homo sapiens (human) | Ki | 0.0540 | 2 | 3 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Ki | 200.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 | Homo sapiens (human) | Ki | 187.0000 | 1 | 1 |
| peroxisome proliferator-activated receptor gamma isoform 2 | Homo sapiens (human) | IC50 | 39.8410 | 1 | 1 |
| Phenol oxidase | Plutella xylostella (diamondback moth) | IC50 | 38.3100 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 9.0000 | 1 | 1 |
| Phosphatidylserine lipase ABHD16A | Homo sapiens (human) | IC50 | 0.1000 | 2 | 2 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | IC50 | 0.0008 | 6 | 7 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | IC50 | 0.0017 | 4 | 5 |
| Phosphorylase b kinase regulatory subunit alpha, liver isoform | Homo sapiens (human) | IC50 | 0.0013 | 2 | 3 |
| Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform | Homo sapiens (human) | IC50 | 0.0013 | 2 | 3 |
| Phosphorylase b kinase regulatory subunit beta | Homo sapiens (human) | IC50 | 0.0013 | 2 | 3 |
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | IC50 | 21.5395 | 2 | 2 |
| Plasma kallikrein | Homo sapiens (human) | IC50 | 20.0170 | 2 | 2 |
| Plasmepsin 4 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0003 | 1 | 1 |
| Plasmepsin-1 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0009 | 1 | 1 |
| Plasmepsin-2 | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 0.0006 | 2 | 2 |
| Plasminogen | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| Plasminogen | Bos taurus (cattle) | IC50 | 3.7000 | 1 | 1 |
| Platelet-activating factor acetylhydrolase | Homo sapiens (human) | IC50 | 0.0500 | 1 | 1 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | IC50 | 0.0007 | 8 | 8 |
| Platelet-derived growth factor receptor alpha | Mus musculus (house mouse) | IC50 | 0.0020 | 1 | 1 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | IC50 | 1.1042 | 10 | 14 |
| Platelet-derived growth factor receptor beta | Mus musculus (house mouse) | IC50 | 0.0020 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 0.3266 | 47 | 67 |
| Polyamine deacetylase HDAC10 | Mus musculus (house mouse) | IC50 | 0.0014 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | Ki | 0.1719 | 3 | 3 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 0.4000 | 5 | 5 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 1.4000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | Ki | 24.2000 | 1 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | IC50 | 95.2000 | 2 | 2 |
| Pro-cathepsin H | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Pro-cathepsin H | Homo sapiens (human) | Ki | 9.2000 | 2 | 2 |
| Probable maltase-glucoamylase 2 | Homo sapiens (human) | IC50 | 115.7500 | 2 | 2 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.2697 | 3 | 3 |
| procathepsin L isoform 1 preproprotein | Homo sapiens (human) | IC50 | 25.1129 | 2 | 2 |
| Programmed cell death protein 4 | Homo sapiens (human) | IC50 | 0.8800 | 1 | 1 |
| Prolyl 4-hydroxylase subunit alpha-1 | Gallus gallus (chicken) | Ki | 20,000.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 0.0560 | 1 | 1 |
| Protease | Human immunodeficiency virus 1 | IC50 | 0.9470 | 3 | 3 |
| Protease | Human immunodeficiency virus 1 | Ki | 0.5172 | 12 | 12 |
| Proteasome subunit beta type-1 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Proteasome subunit beta type-2 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | IC50 | 137.0000 | 1 | 1 |
| Protein cereblon | Homo sapiens (human) | Ki | 67.8000 | 1 | 1 |
| Protein DBF4 homolog A | Homo sapiens (human) | IC50 | 0.0548 | 2 | 2 |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | IC50 | 11.9000 | 1 | 1 |
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | IC50 | 11.9000 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | IC50 | 0.0743 | 21 | 21 |
| Protein kinase C alpha type | Rattus norvegicus (Norway rat) | IC50 | 0.2184 | 14 | 15 |
| Protein kinase C beta type | Homo sapiens (human) | IC50 | 0.0760 | 23 | 24 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | IC50 | 0.1937 | 16 | 17 |
| Protein kinase C beta type | Rattus norvegicus (Norway rat) | Ki | 0.0190 | 1 | 1 |
| Protein kinase C delta type | Homo sapiens (human) | IC50 | 0.1359 | 16 | 16 |
| Protein kinase C delta type | Rattus norvegicus (Norway rat) | IC50 | 0.2511 | 12 | 13 |
| Protein kinase C epsilon type | Homo sapiens (human) | IC50 | 0.0869 | 17 | 17 |
| Protein kinase C epsilon type | Rattus norvegicus (Norway rat) | IC50 | 0.2511 | 12 | 13 |
| Protein kinase C eta type | Homo sapiens (human) | IC50 | 0.1286 | 11 | 11 |
| Protein kinase C eta type | Rattus norvegicus (Norway rat) | IC50 | 0.2511 | 12 | 13 |
| Protein kinase C gamma type | Homo sapiens (human) | IC50 | 0.1237 | 17 | 19 |
| Protein kinase C gamma type | Rattus norvegicus (Norway rat) | IC50 | 0.2209 | 15 | 17 |
| Protein kinase C iota type | Homo sapiens (human) | IC50 | 0.1815 | 10 | 10 |
| Protein kinase C theta type | Homo sapiens (human) | IC50 | 0.1623 | 10 | 12 |
| Protein kinase C theta type | Rattus norvegicus (Norway rat) | IC50 | 0.2511 | 12 | 13 |
| Protein kinase C zeta type | Homo sapiens (human) | IC50 | 0.9573 | 14 | 16 |
| Protein kinase C zeta type | Rattus norvegicus (Norway rat) | IC50 | 0.2511 | 12 | 13 |
| Protein odd-skipped-related 1 | Homo sapiens (human) | IC50 | 0.0402 | 2 | 2 |
| Protein phosphatase 1A | Homo sapiens (human) | IC50 | 0.0030 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | IC50 | 1,800.0000 | 1 | 1 |
| Protein-arginine deiminase type-4 | Homo sapiens (human) | Ki | 560.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | Ki | 79.0000 | 1 | 1 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | IC50 | 0.0095 | 2 | 2 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | IC50 | 0.4840 | 4 | 4 |
| Prothrombin | Bos taurus (cattle) | IC50 | 12.0000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 0.0021 | 12 | 12 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | IC50 | 0.0004 | 6 | 6 |
| Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | IC50 | 0.0063 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 0.3642 | 25 | 25 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 23,750.0000 | 1 | 2 |
| Pteridine reductase 1 | Leishmania major | IC50 | 1,100.0000 | 1 | 1 |
| Putative alpha-glucosidase | Oryza sativa Japonica Group (Japanese rice) | IC50 | 0.0400 | 2 | 2 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.1848 | 25 | 27 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.4119 | 8 | 10 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.3701 | 9 | 11 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 2.1025 | 5 | 5 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | IC50 | 0.0713 | 9 | 9 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | IC50 | 0.0106 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | IC50 | 0.1830 | 8 | 8 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.3560 | 2 | 2 |
| receptor-interacting serine/threonine-protein kinase 2 isoform 1 | Homo sapiens (human) | IC50 | 49.7510 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 0.0014 | 23 | 23 |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | IC50 | 0.2250 | 2 | 2 |
| Renin | Homo sapiens (human) | IC50 | 39.0100 | 5 | 8 |
| Renin | Homo sapiens (human) | Ki | 6.5500 | 2 | 2 |
| Retinoblastoma-associated protein | Homo sapiens (human) | IC50 | 0.0660 | 1 | 1 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 139.0000 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | IC50 | 0.0038 | 6 | 6 |
| Rho-associated protein kinase 2 | Bos taurus (cattle) | IC50 | 0.0417 | 2 | 11 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | IC50 | 0.0045 | 4 | 4 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | IC50 | 0.0680 | 2 | 2 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | IC50 | 0.0053 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | IC50 | 0.0004 | 6 | 6 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | IC50 | 0.0002 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | IC50 | 0.0002 | 3 | 3 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | IC50 | 0.0071 | 2 | 2 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | IC50 | 0.0011 | 3 | 3 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | IC50 | 0.0007 | 4 | 4 |
| Ribosomal protein S6 kinase beta-2 | Homo sapiens (human) | IC50 | 0.0015 | 2 | 2 |
| RNA-directed RNA polymerase | | IC50 | 50.0000 | 2 | 2 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 77.0000 | 1 | 1 |
| sentrin-specific protease 8 | Homo sapiens (human) | IC50 | 1.8500 | 2 | 2 |
| Serine protease hepsin | Homo sapiens (human) | Ki | 0.0610 | 1 | 1 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | IC50 | 0.0080 | 2 | 2 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | IC50 | 0.2385 | 2 | 2 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | IC50 | 0.0386 | 3 | 3 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | IC50 | 0.0258 | 1 | 1 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | IC50 | 0.0065 | 3 | 3 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | IC50 | 0.0029 | 3 | 3 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | IC50 | 0.0124 | 2 | 2 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | IC50 | 0.0034 | 4 | 4 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | IC50 | 0.0374 | 2 | 2 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | IC50 | 0.2320 | 2 | 2 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | IC50 | 0.0373 | 2 | 2 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | IC50 | 0.0037 | 2 | 2 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | IC50 | 0.0012 | 2 | 2 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | IC50 | 0.0013 | 2 | 2 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 0.0107 | 9 | 9 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | IC50 | 0.0007 | 2 | 2 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | IC50 | 0.0028 | 2 | 2 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | IC50 | 0.1772 | 12 | 12 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Ki | 0.0078 | 1 | 1 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | IC50 | 2.7191 | 10 | 10 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | IC50 | 0.1564 | 9 | 9 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | IC50 | 0.0014 | 2 | 2 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | IC50 | 0.1563 | 9 | 9 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | IC50 | 0.2670 | 2 | 2 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | IC50 | 0.0890 | 2 | 2 |
| Serine/threonine-protein kinase haspin | Homo sapiens (human) | IC50 | 0.0422 | 3 | 3 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | IC50 | 0.0443 | 3 | 3 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | IC50 | 0.0130 | 2 | 2 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | IC50 | 0.0062 | 2 | 2 |
| Serine/threonine-protein kinase LMTK3 | Homo sapiens (human) | IC50 | 0.0265 | 2 | 3 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | IC50 | 0.0257 | 2 | 2 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | IC50 | 0.0001 | 2 | 2 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | IC50 | 0.0027 | 2 | 2 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | IC50 | 0.0005 | 2 | 2 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | IC50 | 0.8385 | 12 | 13 |
| Serine/threonine-protein kinase mTOR | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | IC50 | 0.0025 | 4 | 4 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | IC50 | 0.0055 | 4 | 4 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | IC50 | 0.0105 | 2 | 2 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | IC50 | 0.0122 | 3 | 3 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | IC50 | 0.5210 | 2 | 2 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | IC50 | 1.7683 | 3 | 3 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | IC50 | 43.9500 | 2 | 2 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | IC50 | 0.0851 | 2 | 2 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | IC50 | 0.0864 | 2 | 2 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek8 | Homo sapiens (human) | IC50 | 0.0263 | 2 | 2 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | IC50 | 0.1010 | 2 | 2 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | IC50 | 0.1102 | 2 | 2 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | IC50 | 0.0666 | 2 | 2 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 0.0004 | 3 | 3 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | IC50 | 0.0021 | 4 | 4 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | IC50 | 0.0003 | 2 | 2 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | IC50 | 0.0132 | 4 | 4 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | IC50 | 0.0039 | 2 | 2 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | IC50 | 0.0328 | 2 | 2 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 0.0297 | 15 | 16 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | IC50 | 0.0813 | 5 | 5 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | IC50 | 0.0001 | 3 | 3 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 15.6478 | 10 | 10 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Ki | 0.5356 | 1 | 4 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | IC50 | 0.5460 | 6 | 6 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Ki | 0.5356 | 1 | 4 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | IC50 | 5.1015 | 4 | 4 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Ki | 0.5357 | 1 | 4 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | IC50 | 0.0083 | 2 | 2 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Ki | 0.5356 | 1 | 4 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | IC50 | 0.8500 | 1 | 1 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | IC50 | 0.1464 | 2 | 2 |
| Serine/threonine-protein kinase Sgk1 | Homo sapiens (human) | IC50 | 0.0100 | 3 | 3 |
| Serine/threonine-protein kinase Sgk2 | Homo sapiens (human) | IC50 | 0.0158 | 2 | 2 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | IC50 | 0.0730 | 2 | 2 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | IC50 | 0.0009 | 2 | 2 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | IC50 | 0.3669 | 3 | 3 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | IC50 | 0.1541 | 3 | 3 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | IC50 | 0.0598 | 2 | 2 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | IC50 | 0.0008 | 2 | 2 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | IC50 | 0.0076 | 2 | 2 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | IC50 | 0.0017 | 2 | 2 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | IC50 | 0.0030 | 2 | 2 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | IC50 | 0.0295 | 3 | 3 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | IC50 | 0.0035 | 2 | 2 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | IC50 | 0.0096 | 2 | 2 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | IC50 | 0.0032 | 2 | 2 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | IC50 | 0.0027 | 2 | 2 |
| Serine/threonine-protein kinase WNK1 | Homo sapiens (human) | IC50 | 14.8000 | 2 | 2 |
| Serine/threonine-protein kinase WNK2 | Homo sapiens (human) | IC50 | 1.4550 | 2 | 2 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | IC50 | 0.1246 | 2 | 2 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | IC50 | 0.0416 | 2 | 2 |
| Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B | Gallus gallus (chicken) | IC50 | 0.0016 | 2 | 2 |
| Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform | Homo sapiens (human) | IC50 | 0.0001 | 1 | 1 |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Homo sapiens (human) | IC50 | 0.0148 | 1 | 1 |
| Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | Homo sapiens (human) | IC50 | 0.0302 | 10 | 10 |
| Serum paraoxonase/arylesterase 1 | Homo sapiens (human) | Ki | 18,300.0000 | 1 | 1 |
| Sialidase-1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Sialidase-3 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Sialidase-4 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | IC50 | 0.0067 | 2 | 2 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.0059 | 2 | 2 |
| Sodium channel protein type 4 subunit alpha | Homo sapiens (human) | IC50 | 0.0320 | 1 | 1 |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | IC50 | 0.0843 | 2 | 2 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 0.0280 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | Ki | 0.0501 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | IC50 | 0.2745 | 1 | 2 |
| Solute carrier family 22 member 20 | Mus musculus (house mouse) | Ki | 111.3520 | 1 | 4 |
| Solute carrier family 22 member 6 | Mus musculus (house mouse) | Ki | 454.1472 | 3 | 6 |
| Solute carrier organic anion transporter family member 1A1 | Rattus norvegicus (Norway rat) | Ki | 6.6000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A2 | Homo sapiens (human) | Ki | 11.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1A4 | Rattus norvegicus (Norway rat) | Ki | 7.3000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 4.1948 | 3 | 4 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | Ki | 2.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 3.0000 | 1 | 1 |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | Ki | 3.0000 | 1 | 1 |
| Splicing factor 3B subunit 3 | Homo sapiens (human) | IC50 | 0.3034 | 2 | 4 |
| SRSF protein kinase 1 | Homo sapiens (human) | IC50 | 0.0336 | 2 | 2 |
| SRSF protein kinase 2 | Homo sapiens (human) | IC50 | 0.2060 | 2 | 2 |
| SRSF protein kinase 3 | Homo sapiens (human) | IC50 | 1.7700 | 2 | 2 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 0.0142 | 3 | 3 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | IC50 | 0.0158 | 2 | 2 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 500.0000 | 1 | 3 |
| Succinate-semialdehyde dehydrogenase, mitochondrial | Homo sapiens (human) | IC50 | 1,000.0000 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 77.8333 | 3 | 3 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 0.3479 | 14 | 14 |
| Suppressor of tumorigenicity 14 protein | Homo sapiens (human) | Ki | 1.2980 | 2 | 2 |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | IC50 | 0.2250 | 2 | 2 |
| Telomerase reverse transcriptase | Homo sapiens (human) | IC50 | 6.9517 | 6 | 6 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | IC50 | 0.0000 | 2 | 2 |
| Testis-specific serine/threonine-protein kinase 1 | Mus musculus (house mouse) | IC50 | 0.0003 | 1 | 1 |
| Testis-specific serine/threonine-protein kinase 2 | Homo sapiens (human) | IC50 | 0.0038 | 2 | 2 |
| Testis-specific serine/threonine-protein kinase 3 | Homo sapiens (human) | IC50 | 0.0051 | 2 | 2 |
| Testis-specific serine/threonine-protein kinase 6 | Homo sapiens (human) | IC50 | 0.1525 | 2 | 2 |
| TGF-beta receptor type-1 | Homo sapiens (human) | IC50 | 5.7931 | 3 | 7 |
| TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | Homo sapiens (human) | IC50 | 0.0370 | 2 | 2 |
| Thermolysin | Bacillus thermoproteolyticus | IC50 | 35.5665 | 2 | 2 |
| Thermolysin | Bacillus thermoproteolyticus | Ki | 0.0280 | 1 | 1 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 150.0108 | 4 | 4 |
| Thioredoxin reductase 1, cytoplasmic | Rattus norvegicus (Norway rat) | IC50 | 0.8100 | 3 | 3 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 200.0000 | 3 | 3 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 200.0000 | 3 | 3 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 2 |
| Thymidylate synthase | Homo sapiens (human) | IC50 | 500.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 0.0320 | 7 | 7 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | IC50 | 0.0103 | 4 | 4 |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | IC50 | 44.9910 | 2 | 2 |
| Transcription factor 4 | Homo sapiens (human) | IC50 | 0.8000 | 1 | 1 |
| Transcription factor 7-like 2 | Homo sapiens (human) | Ki | 46.4167 | 6 | 6 |
| Transcription factor HES-1 | Mus musculus (house mouse) | IC50 | 6.0000 | 1 | 1 |
| Translocator protein | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| Transmembrane protease serine 6 | Homo sapiens (human) | Ki | 3.2500 | 2 | 2 |
| Transporter | Rattus norvegicus (Norway rat) | Ki | 18.2579 | 2 | 2 |
| Transthyretin | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Trehalase | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Trehalase | Rattus norvegicus (Norway rat) | IC50 | 41.6667 | 3 | 3 |
| Trehalase | Sus scrofa (pig) | IC50 | 41.0000 | 2 | 2 |
| Trehalose synthase/amylase TreS | Mycobacterium tuberculosis CDC1551 | Ki | 0.2500 | 1 | 1 |
| Trypsin | Sus scrofa (pig) | IC50 | 0.3500 | 2 | 2 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 0.6000 | 1 | 1 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 0.6000 | 1 | 1 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 0.6000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 320.0000 | 1 | 1 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | IC50 | 0.1233 | 16 | 16 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | IC50 | 0.0504 | 4 | 4 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | IC50 | 0.0011 | 2 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | IC50 | 2.1676 | 7 | 7 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | IC50 | 0.2071 | 3 | 3 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | IC50 | 0.0008 | 3 | 3 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | IC50 | 0.0039 | 3 | 3 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | IC50 | 0.0009 | 2 | 2 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | IC50 | 0.0108 | 2 | 2 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | IC50 | 0.0929 | 10 | 10 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | IC50 | 0.0025 | 2 | 2 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | IC50 | 5.3379 | 3 | 3 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Ki | 0.0061 | 1 | 2 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | IC50 | 0.0040 | 5 | 5 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | IC50 | 0.0016 | 9 | 9 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | IC50 | 0.0084 | 15 | 15 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 0.1784 | 12 | 12 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | IC50 | 0.0012 | 12 | 12 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | IC50 | 0.0331 | 3 | 3 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | IC50 | 0.0177 | 3 | 3 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | IC50 | 0.0131 | 5 | 5 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | IC50 | 6.5000 | 2 | 2 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 0.0057 | 13 | 13 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | IC50 | 42.6892 | 3 | 3 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | IC50 | 0.0204 | 2 | 2 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | IC50 | 0.0029 | 4 | 4 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | IC50 | 0.0175 | 8 | 8 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 50.0006 | 2 | 2 |
| tyrosine-protein phosphatase non-receptor type 22 isoform 1 | Homo sapiens (human) | IC50 | 1.2950 | 2 | 2 |
| tyrosine-protein phosphatase non-receptor type 7 isoform 2 | Homo sapiens (human) | IC50 | 1.2400 | 1 | 1 |
| V-type proton ATPase subunit S1 | Homo sapiens (human) | IC50 | 0.1000 | 1 | 1 |
| Vacuolar proton pump subunit B | Gallus gallus (chicken) | IC50 | 0.0300 | 1 | 1 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | IC50 | 0.0149 | 7 | 7 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 0.9425 | 34 | 38 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Ki | 0.0017 | 1 | 1 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | IC50 | 0.0146 | 9 | 9 |
| Vitamin D3 receptor | Homo sapiens (human) | IC50 | 0.0870 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Mycobacterium tuberculosis H37Rv | Kd | 0.0400 | 1 | 1 |
| 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Burkholderia pseudomallei K96243 | Kd | 1,000.0000 | 1 | 1 |
| 26S proteasome regulatory subunit 6B | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| 3-phosphoinositide-dependent protein kinase 1 | Homo sapiens (human) | Kd | 0.0017 | 2 | 2 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-1 | Homo sapiens (human) | Kd | 6.0955 | 4 | 5 |
| 5'-AMP-activated protein kinase catalytic subunit alpha-2 | Homo sapiens (human) | Kd | 0.0120 | 2 | 2 |
| 5'-AMP-activated protein kinase subunit gamma-1 | Homo sapiens (human) | Kd | 15.1760 | 1 | 2 |
| 5'-AMP-activated protein kinase subunit gamma-2 | Homo sapiens (human) | Kd | 15.4340 | 1 | 2 |
| AarF domain-containing protein kinase 1 | Homo sapiens (human) | Kd | 18.0450 | 1 | 2 |
| Actin-related protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Actin-related protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Activated CDC42 kinase 1 | Homo sapiens (human) | Kd | 6.3532 | 4 | 5 |
| Activin receptor type-1 | Homo sapiens (human) | Kd | 15.2350 | 3 | 4 |
| Activin receptor type-1B | Homo sapiens (human) | Kd | 11.6545 | 3 | 4 |
| Activin receptor type-2A | Homo sapiens (human) | Kd | 9.4500 | 2 | 2 |
| Activin receptor type-2B | Homo sapiens (human) | Kd | 17.3000 | 3 | 4 |
| Acyl-CoA dehydrogenase family member 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Acyl-CoA dehydrogenase family member 11 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Adenine phosphoribosyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Adenosine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Adenylate kinase 2, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ADP/ATP translocase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ADP/ATP translocase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Albumin | Bos taurus (cattle) | EC50 | 6,300.0000 | 1 | 1 |
| Albumin | Homo sapiens (human) | Kd | 12.0000 | 1 | 2 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | Kd | 10.0213 | 3 | 3 |
| Alpha-crystallin B chain | Homo sapiens (human) | EC50 | 1.4200 | 1 | 1 |
| Angiopoietin-1 receptor | Homo sapiens (human) | Kd | 0.1733 | 3 | 3 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | EC50 | 0.1055 | 1 | 4 |
| Ankyrin repeat and protein kinase domain-containing protein 1 | Homo sapiens (human) | Kd | 0.2700 | 2 | 2 |
| AP2-associated protein kinase 1 | Homo sapiens (human) | Kd | 6.0017 | 4 | 5 |
| ATP-dependent 6-phosphofructokinase, platelet type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent RNA helicase DDX1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent RNA helicase DDX3X | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| ATP-dependent RNA helicase DDX42 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| ATP-dependent RNA helicase DHX30 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Atypical kinase COQ8A, mitochondrial | Homo sapiens (human) | Kd | 22.0000 | 3 | 5 |
| Atypical kinase COQ8B, mitochondrial | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Aurora kinase A | Homo sapiens (human) | Kd | 6.0326 | 4 | 5 |
| Aurora kinase B | Homo sapiens (human) | Kd | 7.5978 | 3 | 4 |
| Aurora kinase C | Homo sapiens (human) | Kd | 0.0190 | 3 | 3 |
| B-cell lymphoma 6 protein | Homo sapiens (human) | Kd | 1,000.0000 | 1 | 1 |
| bcl-2-like protein 11 isoform 1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| BDNF/NT-3 growth factors receptor | Homo sapiens (human) | Kd | 0.0038 | 2 | 2 |
| Beta-adrenergic receptor kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| BMP-2-inducible protein kinase | Homo sapiens (human) | Kd | 6.0210 | 4 | 5 |
| Bone morphogenetic protein receptor type-1A | Homo sapiens (human) | Kd | 16.8500 | 3 | 4 |
| Bone morphogenetic protein receptor type-1B | Homo sapiens (human) | Kd | 20.0567 | 2 | 3 |
| Bone morphogenetic protein receptor type-2 | Homo sapiens (human) | Kd | 18.0750 | 3 | 4 |
| Breakpoint cluster region protein | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Calcium-dependent protein kinase 1 | Plasmodium falciparum 3D7 | Kd | 0.0002 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase kinase 1 | Homo sapiens (human) | Kd | 0.0000 | 3 | 3 |
| Calcium/calmodulin-dependent protein kinase kinase 2 | Homo sapiens (human) | Kd | 6.4555 | 4 | 5 |
| Calcium/calmodulin-dependent protein kinase type 1 | Homo sapiens (human) | Kd | 0.0280 | 3 | 3 |
| Calcium/calmodulin-dependent protein kinase type 1D | Homo sapiens (human) | Kd | 0.0014 | 3 | 3 |
| Calcium/calmodulin-dependent protein kinase type 1G | Homo sapiens (human) | Kd | 7.5248 | 4 | 4 |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | Kd | 0.0001 | 3 | 3 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | Kd | 0.0019 | 3 | 3 |
| Calcium/calmodulin-dependent protein kinase type II subunit delta | Homo sapiens (human) | Kd | 6.0382 | 4 | 5 |
| Calcium/calmodulin-dependent protein kinase type II subunit gamma | Homo sapiens (human) | Kd | 6.0349 | 4 | 5 |
| Calcium/calmodulin-dependent protein kinase type IV | Homo sapiens (human) | Kd | 15.0205 | 3 | 4 |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | Kd | 15.0095 | 3 | 4 |
| cAMP-dependent protein kinase catalytic subunit beta | Homo sapiens (human) | Kd | 15.0145 | 3 | 4 |
| cAMP-dependent protein kinase catalytic subunit gamma | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cAMP-dependent protein kinase catalytic subunit PRKX | Homo sapiens (human) | Kd | 0.0130 | 2 | 2 |
| cAMP-dependent protein kinase type II-alpha regulatory subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Casein kinase I isoform alpha | Homo sapiens (human) | Kd | 20.3233 | 2 | 3 |
| Casein kinase I isoform alpha-like | Homo sapiens (human) | Kd | 0.2500 | 2 | 2 |
| Casein kinase I isoform delta | Homo sapiens (human) | Kd | 16.2000 | 3 | 4 |
| Casein kinase I isoform epsilon | Homo sapiens (human) | Kd | 12.1672 | 4 | 5 |
| Casein kinase I isoform gamma-1 | Homo sapiens (human) | Kd | 18.3750 | 3 | 4 |
| Casein kinase I isoform gamma-2 | Homo sapiens (human) | Kd | 12.5920 | 4 | 5 |
| Casein kinase I isoform gamma-3 | Homo sapiens (human) | Kd | 20.0000 | 3 | 4 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Kd | 0.4880 | 2 | 2 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Kd | 15.0591 | 3 | 4 |
| Cell division control protein 2 homolog | Plasmodium falciparum 3D7 | Kd | 0.8000 | 1 | 1 |
| Cell division cycle 7-related protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| cGMP-dependent protein kinase 1 | Homo sapiens (human) | Kd | 15.0160 | 3 | 4 |
| cGMP-dependent protein kinase 2 | Homo sapiens (human) | Kd | 0.0160 | 2 | 2 |
| Chain A, Acetyl-CoA carboxylase 2 | Homo sapiens (human) | Kd | 0.0010 | 1 | 1 |
| Chain A, BCL-2-RELATED PROTEIN A1 | Homo sapiens (human) | EC50 | 350.0000 | 1 | 1 |
| Chain A, FLAVODOXIN | Nitratidesulfovibrio vulgaris | Kd | 0.0018 | 1 | 11 |
| Chain A, Flavodoxin | Nitratidesulfovibrio vulgaris str. Hildenborough | Kd | 0.0023 | 1 | 8 |
| Chain A, FLAVODOXIN | Synechococcus elongatus PCC 7942 = FACHB-805 | Kd | 0.0011 | 1 | 15 |
| Chain A, Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 0.0100 | 1 | 1 |
| Chain A, Nadh Oxidase | Thermus thermophilus HB8 | Kd | 0.0900 | 1 | 1 |
| Chain A, Protein (fmn-binding Protein) | Nitratidesulfovibrio vulgaris str. 'Miyazaki F' | Kd | 0.0004 | 1 | 1 |
| Chain A, Recoverin | Bos taurus (cattle) | Kd | 100.0000 | 1 | 1 |
| Chain A, RIO-type serine/threonine-protein kinase Rio1 | Archaeoglobus fulgidus | Kd | 0.0400 | 1 | 1 |
| Chain B, Protein (fmn-binding Protein) | Nitratidesulfovibrio vulgaris str. 'Miyazaki F' | Kd | 0.0004 | 1 | 1 |
| Choline-phosphate cytidylyltransferase A | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Chromodomain-helicase-DNA-binding protein 4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Citron Rho-interacting kinase | Homo sapiens (human) | Kd | 15.1700 | 3 | 4 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cyclin-dependent kinase 11A | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 11B | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cyclin-dependent kinase 13 | Homo sapiens (human) | Kd | 20.0233 | 2 | 3 |
| Cyclin-dependent kinase 14 | Homo sapiens (human) | Kd | 0.1600 | 2 | 2 |
| Cyclin-dependent kinase 15 | Homo sapiens (human) | Kd | 0.2600 | 1 | 1 |
| Cyclin-dependent kinase 16 | Homo sapiens (human) | Kd | 12.0146 | 4 | 5 |
| Cyclin-dependent kinase 17 | Homo sapiens (human) | Kd | 15.0480 | 3 | 4 |
| Cyclin-dependent kinase 18 | Homo sapiens (human) | Kd | 10.1800 | 3 | 3 |
| Cyclin-dependent kinase 19 | Homo sapiens (human) | Kd | 0.1900 | 2 | 2 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | Kd | 6.0246 | 4 | 5 |
| Cyclin-dependent kinase 3 | Homo sapiens (human) | Kd | 0.0307 | 3 | 3 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | Kd | 7.5210 | 3 | 4 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | Kd | 15.1995 | 1 | 2 |
| Cyclin-dependent kinase 7 | Homo sapiens (human) | Kd | 15.0225 | 3 | 4 |
| Cyclin-dependent kinase 8 | Homo sapiens (human) | Kd | 0.5100 | 2 | 2 |
| Cyclin-dependent kinase 9 | Homo sapiens (human) | Kd | 15.0500 | 3 | 4 |
| Cyclin-dependent kinase-like 1 | Homo sapiens (human) | Kd | 0.3300 | 1 | 1 |
| Cyclin-dependent kinase-like 2 | Homo sapiens (human) | Kd | 0.5100 | 1 | 1 |
| Cyclin-dependent kinase-like 3 | Homo sapiens (human) | Kd | 5.1000 | 1 | 1 |
| Cyclin-dependent kinase-like 5 | Homo sapiens (human) | Kd | 20.1133 | 2 | 3 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | Kd | 6.2336 | 4 | 5 |
| Cyclin-G-associated kinase | Homo sapiens (human) | Kd | 6.2742 | 4 | 5 |
| Cysteine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Cytochrome c1, heme protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Cytoplasmic tyrosine-protein kinase BMX | Homo sapiens (human) | Kd | 0.2500 | 3 | 3 |
| dCTP pyrophosphatase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Death-associated protein kinase 1 | Homo sapiens (human) | Kd | 0.0014 | 2 | 2 |
| Death-associated protein kinase 2 | Homo sapiens (human) | Kd | 0.0021 | 3 | 3 |
| Death-associated protein kinase 3 | Homo sapiens (human) | Kd | 0.3757 | 4 | 4 |
| Delta(24)-sterol reductase | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Deoxycytidine kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Discoidin domain-containing receptor 2 | Homo sapiens (human) | Kd | 15.0210 | 3 | 4 |
| DNA replication licensing factor MCM4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| DNA topoisomerase 2-beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| DnaJ homolog subfamily A member 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual serine/threonine and tyrosine protein kinase | Homo sapiens (human) | Kd | 0.0110 | 1 | 1 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | Kd | 7.9472 | 3 | 4 |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | Kd | 7.6325 | 3 | 4 |
| Dual specificity mitogen-activated protein kinase kinase 3 | Homo sapiens (human) | Kd | 15.0025 | 3 | 4 |
| Dual specificity mitogen-activated protein kinase kinase 4 | Homo sapiens (human) | Kd | 10.0467 | 3 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 5 | Homo sapiens (human) | Kd | 10.6786 | 2 | 3 |
| Dual specificity mitogen-activated protein kinase kinase 6 | Homo sapiens (human) | Kd | 7.5237 | 3 | 4 |
| Dual specificity mitogen-activated protein kinase kinase 7 | Homo sapiens (human) | Kd | 0.0300 | 1 | 1 |
| Dual specificity protein kinase CLK1 | Homo sapiens (human) | Kd | 6.0202 | 4 | 5 |
| Dual specificity protein kinase CLK2 | Homo sapiens (human) | Kd | 6.7675 | 4 | 5 |
| Dual specificity protein kinase CLK3 | Homo sapiens (human) | Kd | 8.8300 | 4 | 4 |
| Dual specificity protein kinase CLK4 | Homo sapiens (human) | Kd | 6.0098 | 4 | 5 |
| Dual specificity protein kinase TTK | Homo sapiens (human) | Kd | 10.0420 | 4 | 6 |
| Dual specificity testis-specific protein kinase 1 | Homo sapiens (human) | Kd | 15.1600 | 3 | 4 |
| Dual specificity testis-specific protein kinase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1A | Homo sapiens (human) | Kd | 11.6187 | 2 | 3 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Homo sapiens (human) | Kd | 15.0140 | 3 | 4 |
| Dual specificity tyrosine-phosphorylation-regulated kinase 2 | Homo sapiens (human) | Kd | 0.2500 | 1 | 1 |
| Dynamin-like 120 kDa protein, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| eIF-2-alpha kinase GCN2 | Homo sapiens (human) | Kd | 0.0160 | 2 | 2 |
| EKC/KEOPS complex subunit TP53RK | Homo sapiens (human) | Kd | 21.2800 | 1 | 3 |
| Electron transfer flavoprotein subunit beta | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Elongation factor Tu, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Ephrin type-A receptor 1 | Homo sapiens (human) | Kd | 15.1500 | 3 | 4 |
| Ephrin type-A receptor 2 | Homo sapiens (human) | Kd | 12.6540 | 4 | 5 |
| Ephrin type-A receptor 3 | Homo sapiens (human) | Kd | 0.0363 | 3 | 3 |
| Ephrin type-A receptor 4 | Homo sapiens (human) | Kd | 12.2580 | 4 | 5 |
| Ephrin type-A receptor 5 | Homo sapiens (human) | Kd | 12.0680 | 4 | 5 |
| Ephrin type-A receptor 6 | Homo sapiens (human) | Kd | 0.2733 | 3 | 3 |
| Ephrin type-A receptor 7 | Homo sapiens (human) | Kd | 7.9875 | 4 | 4 |
| Ephrin type-A receptor 8 | Homo sapiens (human) | Kd | 0.2267 | 3 | 3 |
| Ephrin type-B receptor 1 | Homo sapiens (human) | Kd | 0.3567 | 3 | 3 |
| Ephrin type-B receptor 2 | Homo sapiens (human) | Kd | 16.0500 | 3 | 4 |
| Ephrin type-B receptor 3 | Homo sapiens (human) | Kd | 20.0000 | 3 | 4 |
| Ephrin type-B receptor 4 | Homo sapiens (human) | Kd | 20.4400 | 3 | 5 |
| Ephrin type-B receptor 6 | Homo sapiens (human) | Kd | 20.0700 | 2 | 3 |
| Epidermal growth factor receptor | Homo sapiens (human) | Kd | 2.7593 | 24 | 25 |
| Epithelial discoidin domain-containing receptor 1 | Homo sapiens (human) | Kd | 18.0076 | 3 | 5 |
| Estrogen receptor | Rattus norvegicus (Norway rat) | EC50 | 0.4230 | 1 | 2 |
| Estrogen receptor beta | Rattus norvegicus (Norway rat) | EC50 | 0.4230 | 1 | 2 |
| Eukaryotic translation initiation factor 2-alpha kinase 1 | Homo sapiens (human) | Kd | 23.3333 | 2 | 3 |
| Eukaryotic translation initiation factor 4E | Homo sapiens (human) | Kd | 0.0005 | 1 | 1 |
| Eukaryotic translation initiation factor 5B | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Exosome RNA helicase MTR4 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ferrochelatase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Fibroblast growth factor receptor 1 | Homo sapiens (human) | Kd | 15.0400 | 4 | 6 |
| Fibroblast growth factor receptor 2 | Homo sapiens (human) | Kd | 0.1200 | 3 | 3 |
| Fibroblast growth factor receptor 3 | Homo sapiens (human) | Kd | 0.1812 | 5 | 5 |
| Fibroblast growth factor receptor 4 | Homo sapiens (human) | Kd | 0.2500 | 2 | 2 |
| Focal adhesion kinase 1 | Homo sapiens (human) | Kd | 12.0392 | 4 | 5 |
| G protein-coupled receptor kinase 4 | Homo sapiens (human) | Kd | 0.0370 | 1 | 1 |
| G protein-coupled receptor kinase 6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| G-protein coupled receptor 84 | Homo sapiens (human) | EC50 | 1.0010 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | EC50 | 100,000.0000 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | EC50 | 100,000.0000 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | EC50 | 100,000.0000 | 2 | 2 |
| General transcription and DNA repair factor IIH helicase subunit XPD | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycine--tRNA ligase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycogen phosphorylase, brain form | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | Kd | 15.0700 | 3 | 4 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | Kd | 15.0345 | 3 | 4 |
| glycogen synthase kinase-3 beta isoform 1 | Homo sapiens (human) | EC50 | 220.9133 | 1 | 3 |
| GTP-binding nuclear protein Ran | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Heat shock cognate 71 kDa protein | Homo sapiens (human) | Kd | 59.3462 | 1 | 4 |
| heat shock protein 90 | Candida albicans | EC50 | 75.7405 | 1 | 2 |
| Heme oxygenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | Kd | 10.1083 | 5 | 6 |
| High affinity nerve growth factor receptor | Homo sapiens (human) | Kd | 6.3498 | 4 | 5 |
| Histamine H1 receptor | Cavia porcellus (domestic guinea pig) | EC50 | 50.0000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | EC50 | 3.5000 | 2 | 2 |
| Histone deacetylase 1 | Homo sapiens (human) | Kd | 0.0137 | 1 | 2 |
| Histone deacetylase 2 | Homo sapiens (human) | Kd | 0.0137 | 1 | 2 |
| Histone deacetylase 4 | Homo sapiens (human) | EC50 | 2.5000 | 1 | 2 |
| Histone deacetylase 6 | Homo sapiens (human) | EC50 | 0.0052 | 1 | 1 |
| Homeodomain-interacting protein kinase 1 | Homo sapiens (human) | Kd | 2.7000 | 1 | 1 |
| Homeodomain-interacting protein kinase 2 | Homo sapiens (human) | Kd | 0.1900 | 1 | 1 |
| Homeodomain-interacting protein kinase 3 | Homo sapiens (human) | Kd | 0.0750 | 1 | 1 |
| Homeodomain-interacting protein kinase 4 | Homo sapiens (human) | Kd | 0.3900 | 1 | 1 |
| Hormonally up-regulated neu tumor-associated kinase | Homo sapiens (human) | Kd | 0.6200 | 1 | 1 |
| Hsf1 protein | Mus musculus (house mouse) | EC50 | 1.6500 | 1 | 2 |
| Hydroxycarboxylic acid receptor 1 | Homo sapiens (human) | EC50 | 184.0000 | 1 | 1 |
| Hydroxycarboxylic acid receptor 2 | Homo sapiens (human) | EC50 | 215.0000 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | EC50 | 17.8000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | Kd | 0.0058 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | Kd | 0.0310 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit epsilon | Homo sapiens (human) | Kd | 7.6260 | 3 | 4 |
| Inosine-5'-monophosphate dehydrogenase 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Insulin receptor | Homo sapiens (human) | Kd | 12.0586 | 4 | 5 |
| Insulin receptor-related protein | Homo sapiens (human) | Kd | 0.0810 | 2 | 2 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | Kd | 18.0840 | 3 | 5 |
| Integrin-linked protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Interferon-induced, double-stranded RNA-activated protein kinase | Homo sapiens (human) | Kd | 0.3600 | 2 | 2 |
| Interleukin-1 receptor-associated kinase 1 | Homo sapiens (human) | Kd | 20.0133 | 2 | 3 |
| Interleukin-1 receptor-associated kinase 3 | Homo sapiens (human) | Kd | 7.5700 | 3 | 4 |
| Interleukin-1 receptor-associated kinase 4 | Homo sapiens (human) | Kd | 10.0036 | 2 | 3 |
| Isoleucine--tRNA ligase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 0.0017 | 2 | 2 |
| Leukocyte tyrosine kinase receptor | Homo sapiens (human) | Kd | 0.0370 | 2 | 2 |
| Leukotriene C4 synthase | Cavia porcellus (domestic guinea pig) | Kd | 3.5000 | 1 | 1 |
| LIM domain kinase 1 | Homo sapiens (human) | Kd | 12.3300 | 4 | 5 |
| LIM domain kinase 2 | Homo sapiens (human) | Kd | 19.6000 | 3 | 4 |
| Long-chain-fatty-acid--CoA ligase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| LuxR family transcriptional regulator | Pseudomonas aeruginosa | EC50 | 0.0184 | 2 | 2 |
| Macrophage colony-stimulating factor 1 receptor | Homo sapiens (human) | Kd | 0.0120 | 2 | 2 |
| Macrophage-stimulating protein receptor | Homo sapiens (human) | Kd | 20.1333 | 2 | 3 |
| MAP kinase-activated protein kinase 2 | Homo sapiens (human) | Kd | 15.4400 | 3 | 4 |
| MAP kinase-activated protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| MAP kinase-activated protein kinase 5 | Homo sapiens (human) | Kd | 17.5675 | 3 | 4 |
| MAP kinase-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 0.1700 | 2 | 2 |
| MAP kinase-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 0.0187 | 3 | 3 |
| MAP/microtubule affinity-regulating kinase 3 | Homo sapiens (human) | Kd | 7.5975 | 3 | 4 |
| MAP/microtubule affinity-regulating kinase 4 | Homo sapiens (human) | Kd | 7.5097 | 3 | 4 |
| Mast/stem cell growth factor receptor Kit | Homo sapiens (human) | Kd | 0.0192 | 16 | 16 |
| Maternal embryonic leucine zipper kinase | Homo sapiens (human) | Kd | 7.5372 | 3 | 4 |
| Megakaryocyte-associated tyrosine-protein kinase | Homo sapiens (human) | Kd | 0.2600 | 1 | 1 |
| Membrane-associated progesterone receptor component 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase | Homo sapiens (human) | Kd | 20.0000 | 3 | 4 |
| Metabotropic glutamate receptor 1 | Homo sapiens (human) | EC50 | 1,000.0000 | 1 | 1 |
| Metabotropic glutamate receptor 2 | Homo sapiens (human) | EC50 | 1,000.0000 | 1 | 1 |
| Metabotropic glutamate receptor 6 | Homo sapiens (human) | EC50 | 1,000.0000 | 1 | 1 |
| Microtubule-associated serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 0.1500 | 1 | 1 |
| Midasin | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Misshapen-like kinase 1 | Homo sapiens (human) | Kd | 20.0003 | 2 | 3 |
| Mitogen-activated protein kinase 1 | Homo sapiens (human) | Kd | 18.6500 | 3 | 4 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | Kd | 12.1120 | 4 | 5 |
| Mitogen-activated protein kinase 11 | Homo sapiens (human) | Kd | 20.0000 | 3 | 4 |
| Mitogen-activated protein kinase 12 | Homo sapiens (human) | Kd | 0.0587 | 3 | 3 |
| Mitogen-activated protein kinase 13 | Homo sapiens (human) | Kd | 0.2400 | 1 | 1 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | Kd | 20.0000 | 3 | 4 |
| Mitogen-activated protein kinase 15 | Homo sapiens (human) | Kd | 7.5592 | 3 | 4 |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | Kd | 19.2000 | 3 | 4 |
| Mitogen-activated protein kinase 4 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Mitogen-activated protein kinase 6 | Homo sapiens (human) | Kd | 6.5500 | 2 | 2 |
| Mitogen-activated protein kinase 7 | Homo sapiens (human) | Kd | 15.8000 | 3 | 4 |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | Kd | 6.3022 | 4 | 5 |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | Kd | 8.5992 | 4 | 5 |
| Mitogen-activated protein kinase kinase kinase 1 | Homo sapiens (human) | Kd | 20.1167 | 2 | 3 |
| Mitogen-activated protein kinase kinase kinase 10 | Homo sapiens (human) | Kd | 0.0520 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase 11 | Homo sapiens (human) | Kd | 6.1264 | 4 | 5 |
| Mitogen-activated protein kinase kinase kinase 12 | Homo sapiens (human) | Kd | 1.5000 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 13 | Homo sapiens (human) | Kd | 0.2100 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 15 | Homo sapiens (human) | Kd | 0.0025 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 19 | Homo sapiens (human) | Kd | 0.0009 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 2 | Homo sapiens (human) | Kd | 11.3735 | 2 | 3 |
| Mitogen-activated protein kinase kinase kinase 20 | Homo sapiens (human) | Kd | 22.0000 | 3 | 5 |
| Mitogen-activated protein kinase kinase kinase 3 | Homo sapiens (human) | Kd | 20.9333 | 2 | 3 |
| Mitogen-activated protein kinase kinase kinase 4 | Homo sapiens (human) | Kd | 12.9200 | 4 | 5 |
| Mitogen-activated protein kinase kinase kinase 5 | Homo sapiens (human) | Kd | 5.1053 | 5 | 6 |
| Mitogen-activated protein kinase kinase kinase 6 | Homo sapiens (human) | Kd | 10.1983 | 2 | 3 |
| Mitogen-activated protein kinase kinase kinase 7 | Homo sapiens (human) | Kd | 0.0670 | 1 | 1 |
| Mitogen-activated protein kinase kinase kinase 9 | Homo sapiens (human) | Kd | 0.0100 | 2 | 2 |
| Mitogen-activated protein kinase kinase kinase kinase 1 | Homo sapiens (human) | Kd | 7.6152 | 3 | 4 |
| Mitogen-activated protein kinase kinase kinase kinase 2 | Homo sapiens (human) | Kd | 10.0466 | 2 | 3 |
| Mitogen-activated protein kinase kinase kinase kinase 3 | Homo sapiens (human) | Kd | 8.0976 | 3 | 4 |
| Mitogen-activated protein kinase kinase kinase kinase 4 | Homo sapiens (human) | Kd | 7.5168 | 3 | 4 |
| Mitogen-activated protein kinase kinase kinase kinase 5 | Homo sapiens (human) | Kd | 10.0425 | 4 | 6 |
| Mitotic checkpoint serine/threonine-protein kinase BUB1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Multifunctional protein ADE2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Muscle, skeletal receptor tyrosine-protein kinase | Homo sapiens (human) | Kd | 0.0860 | 2 | 2 |
| Myosin light chain kinase 2, skeletal/cardiac muscle | Homo sapiens (human) | Kd | 0.0773 | 3 | 3 |
| Myosin light chain kinase 3 | Homo sapiens (human) | Kd | 10.0793 | 2 | 3 |
| Myosin light chain kinase family member 4 | Homo sapiens (human) | Kd | 0.4700 | 2 | 2 |
| Myosin light chain kinase, smooth muscle | Gallus gallus (chicken) | Kd | 0.1400 | 1 | 1 |
| Myosin light chain kinase, smooth muscle | Homo sapiens (human) | Kd | 18.0060 | 3 | 5 |
| Myosin-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Myosin-14 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Myosin-IIIa | Homo sapiens (human) | Kd | 0.5000 | 2 | 2 |
| Myosin-IIIb | Homo sapiens (human) | Kd | 0.3000 | 2 | 2 |
| Myotonin-protein kinase | Homo sapiens (human) | Kd | 0.0035 | 2 | 2 |
| NAD-dependent protein deacetylase sirtuin-6 | Homo sapiens (human) | Kd | 183.5000 | 4 | 4 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Non-receptor tyrosine-protein kinase TNK1 | Homo sapiens (human) | Kd | 7.5730 | 3 | 4 |
| Non-receptor tyrosine-protein kinase TYK2 | Homo sapiens (human) | Kd | 12.6424 | 4 | 5 |
| NS5 | Zika virus | EC50 | 1.3000 | 4 | 4 |
| NT-3 growth factor receptor | Homo sapiens (human) | Kd | 0.0170 | 2 | 2 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | Kd | 0.0044 | 2 | 2 |
| NUAK family SNF1-like kinase 2 | Homo sapiens (human) | Kd | 10.0001 | 3 | 3 |
| Nuclear receptor subfamily 1 group I member 2 | Homo sapiens (human) | EC50 | 9.1380 | 2 | 5 |
| Nucleolar GTP-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Obg-like ATPase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | Kd | 3.2400 | 1 | 1 |
| PAS domain-containing serine/threonine-protein kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | EC50 | 0.0101 | 4 | 4 |
| Peptidyl-prolyl cis-trans isomerase FKBP1B | Homo sapiens (human) | Kd | 0.0003 | 1 | 2 |
| Peripheral plasma membrane protein CASK | Homo sapiens (human) | Kd | 0.0190 | 1 | 1 |
| Peroxiredoxin-1 | Homo sapiens (human) | Kd | 2.6100 | 1 | 1 |
| Peroxisomal acyl-coenzyme A oxidase 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Peroxisomal acyl-coenzyme A oxidase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Phenylalanine--tRNA ligase beta subunit | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Phosphatidylethanolamine-binding protein 1 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| Phosphatidylinositol 4-kinase beta | Homo sapiens (human) | Kd | 0.4600 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma | Homo sapiens (human) | Kd | 0.4300 | 1 | 1 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha | Homo sapiens (human) | Kd | 0.0430 | 2 | 2 |
| Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma | Homo sapiens (human) | Kd | 2.7000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Homo sapiens (human) | Kd | 9.2000 | 12 | 12 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | Kd | 1.8000 | 1 | 1 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | Homo sapiens (human) | Kd | 0.0770 | 2 | 2 |
| Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | Homo sapiens (human) | Kd | 23.3333 | 2 | 3 |
| Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Homo sapiens (human) | Kd | 6.6529 | 4 | 5 |
| Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Homo sapiens (human) | Kd | 0.0006 | 3 | 3 |
| Platelet-derived growth factor receptor alpha | Homo sapiens (human) | Kd | 0.0100 | 2 | 2 |
| Platelet-derived growth factor receptor beta | Homo sapiens (human) | Kd | 6.2025 | 4 | 5 |
| Probable ATP-dependent RNA helicase DDX6 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Procathepsin L | Homo sapiens (human) | EC50 | 0.1055 | 1 | 4 |
| Programmed cell death protein 4 | Homo sapiens (human) | EC50 | 0.0500 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | Kd | 0.1300 | 1 | 1 |
| Protein kinase C alpha type | Homo sapiens (human) | Kd | 10.7767 | 2 | 3 |
| Protein kinase C beta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein kinase C delta type | Homo sapiens (human) | Kd | 18.0006 | 3 | 5 |
| Protein kinase C epsilon type | Homo sapiens (human) | Kd | 0.0002 | 2 | 2 |
| Protein kinase C eta type | Homo sapiens (human) | Kd | 0.0048 | 2 | 2 |
| Protein kinase C iota type | Homo sapiens (human) | Kd | 20.0087 | 2 | 3 |
| Protein kinase C theta type | Homo sapiens (human) | Kd | 15.0042 | 3 | 4 |
| Protein kinase C zeta type | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Protein-tyrosine kinase 2-beta | Homo sapiens (human) | Kd | 7.8418 | 3 | 4 |
| Protein-tyrosine kinase 6 | Homo sapiens (human) | Kd | 16.1500 | 3 | 4 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | Kd | 3.8478 | 7 | 8 |
| Proto-oncogene tyrosine-protein kinase ROS | Homo sapiens (human) | Kd | 0.0300 | 2 | 2 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | Kd | 10.0467 | 5 | 6 |
| Putative heat shock protein HSP 90-beta 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Pyridoxal kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Rab-like protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | EC50 | 0.4600 | 2 | 2 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | Kd | 15.0100 | 3 | 4 |
| RAC-beta serine/threonine-protein kinase | Homo sapiens (human) | Kd | 15.0220 | 3 | 4 |
| RAC-gamma serine/threonine-protein kinase | Homo sapiens (human) | Kd | 15.0850 | 3 | 4 |
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Ras-related protein Rab-10 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-27A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Ras-related protein Rab-6A | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Receptor tyrosine-protein kinase erbB-2 | Homo sapiens (human) | Kd | 5.0950 | 2 | 2 |
| Receptor tyrosine-protein kinase erbB-3 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Receptor tyrosine-protein kinase erbB-4 | Homo sapiens (human) | Kd | 0.7700 | 1 | 1 |
| Receptor-interacting serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | Kd | 9.2052 | 4 | 5 |
| Receptor-interacting serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Receptor-interacting serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 0.1100 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | Kd | 1.8912 | 15 | 16 |
| recombinase A | Mycobacterium tuberculosis H37Rv | EC50 | 0.0541 | 2 | 2 |
| regulator of G-protein signaling 16 | Homo sapiens (human) | EC50 | 2.2400 | 1 | 1 |
| regulator of G-protein signaling 19 | Homo sapiens (human) | EC50 | 2.0600 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | EC50 | 2.5900 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | EC50 | 0.1055 | 1 | 4 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | EC50 | 0.1055 | 1 | 4 |
| Replicase polyprotein 1ab | Human coronavirus 229E | EC50 | 0.1055 | 1 | 4 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | EC50 | 0.1055 | 1 | 4 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | EC50 | 0.1055 | 1 | 4 |
| RGS7, partial | Homo sapiens (human) | EC50 | 2.3600 | 1 | 1 |
| Rho-associated protein kinase 1 | Homo sapiens (human) | Kd | 20.0001 | 2 | 3 |
| Rho-associated protein kinase 2 | Homo sapiens (human) | Kd | 22.5001 | 2 | 4 |
| Rhodopsin kinase GRK1 | Homo sapiens (human) | Kd | 0.0010 | 1 | 1 |
| Rhodopsin kinase GRK7 | Homo sapiens (human) | Kd | 0.0009 | 1 | 1 |
| Ribosomal protein S6 kinase alpha-1 | Homo sapiens (human) | Kd | 5.9133 | 5 | 6 |
| Ribosomal protein S6 kinase alpha-2 | Homo sapiens (human) | Kd | 0.0816 | 5 | 5 |
| Ribosomal protein S6 kinase alpha-3 | Homo sapiens (human) | Kd | 6.6376 | 4 | 5 |
| Ribosomal protein S6 kinase alpha-4 | Homo sapiens (human) | Kd | 5.8453 | 5 | 6 |
| Ribosomal protein S6 kinase alpha-5 | Homo sapiens (human) | Kd | 6.6490 | 6 | 7 |
| Ribosomal protein S6 kinase alpha-6 | Homo sapiens (human) | Kd | 6.4695 | 5 | 6 |
| Ribosomal protein S6 kinase beta-1 | Homo sapiens (human) | Kd | 20.0004 | 2 | 3 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Kd | 17.0155 | 1 | 2 |
| RNA cytidine acetyltransferase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| RNA-directed RNA polymerase | | EC50 | 50.0000 | 1 | 1 |
| RPL19A | Saccharomyces cerevisiae (brewer's yeast) | EC50 | 0.7570 | 2 | 2 |
| S-adenosylmethionine synthase isoform type-2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Septin-9 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase 10 | Homo sapiens (human) | Kd | 6.0962 | 4 | 5 |
| Serine/threonine-protein kinase 16 | Homo sapiens (human) | Kd | 12.1480 | 4 | 5 |
| Serine/threonine-protein kinase 17A | Homo sapiens (human) | Kd | 0.0170 | 3 | 3 |
| Serine/threonine-protein kinase 17B | Homo sapiens (human) | Kd | 0.0227 | 3 | 3 |
| Serine/threonine-protein kinase 24 | Homo sapiens (human) | Kd | 15.0600 | 3 | 4 |
| Serine/threonine-protein kinase 25 | Homo sapiens (human) | Kd | 0.1100 | 2 | 2 |
| Serine/threonine-protein kinase 26 | Homo sapiens (human) | Kd | 15.0700 | 3 | 4 |
| Serine/threonine-protein kinase 3 | Homo sapiens (human) | Kd | 7.5108 | 3 | 4 |
| Serine/threonine-protein kinase 3 | Mus musculus (house mouse) | Kd | 0.0001 | 1 | 1 |
| Serine/threonine-protein kinase 32A | Homo sapiens (human) | Kd | 0.0130 | 1 | 1 |
| Serine/threonine-protein kinase 32B | Homo sapiens (human) | Kd | 0.0980 | 2 | 2 |
| Serine/threonine-protein kinase 32C | Homo sapiens (human) | Kd | 0.3100 | 2 | 2 |
| Serine/threonine-protein kinase 33 | Homo sapiens (human) | Kd | 0.0018 | 2 | 2 |
| Serine/threonine-protein kinase 35 | Homo sapiens (human) | Kd | 0.1400 | 1 | 1 |
| Serine/threonine-protein kinase 36 | Homo sapiens (human) | Kd | 5.4333 | 3 | 3 |
| Serine/threonine-protein kinase 38 | Homo sapiens (human) | Kd | 15.0280 | 2 | 2 |
| Serine/threonine-protein kinase 38-like | Homo sapiens (human) | Kd | 0.5675 | 4 | 4 |
| Serine/threonine-protein kinase 4 | Homo sapiens (human) | Kd | 6.0059 | 4 | 5 |
| Serine/threonine-protein kinase A-Raf | Homo sapiens (human) | Kd | 30.0000 | 1 | 3 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | Kd | 16.6667 | 5 | 6 |
| Serine/threonine-protein kinase BRSK1 | Homo sapiens (human) | Kd | 0.0260 | 2 | 2 |
| Serine/threonine-protein kinase BRSK2 | Homo sapiens (human) | Kd | 0.0035 | 2 | 2 |
| Serine/threonine-protein kinase Chk1 | Homo sapiens (human) | Kd | 7.5321 | 3 | 4 |
| Serine/threonine-protein kinase Chk2 | Homo sapiens (human) | Kd | 0.0740 | 1 | 1 |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | Kd | 0.0270 | 2 | 2 |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | Kd | 7.5435 | 3 | 4 |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | Kd | 7.5185 | 3 | 4 |
| Serine/threonine-protein kinase DCLK1 | Homo sapiens (human) | Kd | 0.1100 | 2 | 2 |
| Serine/threonine-protein kinase DCLK2 | Homo sapiens (human) | Kd | 0.0730 | 2 | 2 |
| Serine/threonine-protein kinase DCLK3 | Homo sapiens (human) | Kd | 0.0170 | 2 | 2 |
| Serine/threonine-protein kinase ICK | Homo sapiens (human) | Kd | 20.0053 | 2 | 3 |
| Serine/threonine-protein kinase LATS1 | Homo sapiens (human) | Kd | 7.5378 | 3 | 4 |
| Serine/threonine-protein kinase LATS2 | Homo sapiens (human) | Kd | 0.0170 | 2 | 2 |
| Serine/threonine-protein kinase MAK | Homo sapiens (human) | Kd | 2.6000 | 1 | 1 |
| Serine/threonine-protein kinase MARK1 | Homo sapiens (human) | Kd | 0.0040 | 2 | 2 |
| Serine/threonine-protein kinase MARK2 | Homo sapiens (human) | Kd | 6.1411 | 4 | 5 |
| Serine/threonine-protein kinase MRCK alpha | Homo sapiens (human) | Kd | 15.0285 | 3 | 4 |
| Serine/threonine-protein kinase MRCK beta | Homo sapiens (human) | Kd | 15.0210 | 3 | 4 |
| Serine/threonine-protein kinase MRCK gamma | Homo sapiens (human) | Kd | 15.0185 | 3 | 4 |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | Kd | 5.0003 | 2 | 2 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | Kd | 7.5666 | 3 | 4 |
| Serine/threonine-protein kinase N2 | Homo sapiens (human) | Kd | 7.5915 | 3 | 4 |
| Serine/threonine-protein kinase N3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Serine/threonine-protein kinase Nek1 | Homo sapiens (human) | Kd | 15.4300 | 3 | 4 |
| Serine/threonine-protein kinase Nek11 | Homo sapiens (human) | Kd | 3.1000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | Kd | 12.4480 | 4 | 5 |
| Serine/threonine-protein kinase Nek3 | Homo sapiens (human) | Kd | 23.3333 | 2 | 3 |
| Serine/threonine-protein kinase Nek4 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase Nek5 | Homo sapiens (human) | Kd | 0.8100 | 2 | 2 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | Kd | 10.0000 | 2 | 2 |
| Serine/threonine-protein kinase Nek7 | Homo sapiens (human) | Kd | 3.0010 | 3 | 3 |
| Serine/threonine-protein kinase Nek9 | Homo sapiens (human) | Kd | 14.5800 | 4 | 5 |
| Serine/threonine-protein kinase NIM1 | Homo sapiens (human) | Kd | 0.1400 | 1 | 1 |
| Serine/threonine-protein kinase NLK | Homo sapiens (human) | Kd | 15.1100 | 3 | 4 |
| Serine/threonine-protein kinase OSR1 | Homo sapiens (human) | Kd | 0.4400 | 1 | 1 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | Kd | 0.0010 | 3 | 3 |
| Serine/threonine-protein kinase PAK 2 | Homo sapiens (human) | Kd | 15.0016 | 3 | 4 |
| Serine/threonine-protein kinase PAK 3 | Homo sapiens (human) | Kd | 0.0049 | 3 | 3 |
| Serine/threonine-protein kinase PAK 4 | Homo sapiens (human) | Kd | 6.0729 | 4 | 5 |
| Serine/threonine-protein kinase PAK 5 | Homo sapiens (human) | Kd | 0.0018 | 3 | 3 |
| Serine/threonine-protein kinase PAK 6 | Homo sapiens (human) | Kd | 7.5004 | 4 | 4 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | Kd | 10.0038 | 5 | 6 |
| Serine/threonine-protein kinase pim-2 | Homo sapiens (human) | Kd | 7.5020 | 4 | 4 |
| Serine/threonine-protein kinase pim-3 | Homo sapiens (human) | Kd | 0.0005 | 2 | 2 |
| Serine/threonine-protein kinase PknB | Mycobacterium tuberculosis H37Rv | Kd | 0.0880 | 1 | 1 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Kd | 10.1267 | 3 | 3 |
| Serine/threonine-protein kinase PLK2 | Homo sapiens (human) | Kd | 0.2000 | 1 | 1 |
| Serine/threonine-protein kinase PLK3 | Homo sapiens (human) | Kd | 0.9100 | 2 | 2 |
| Serine/threonine-protein kinase PLK4 | Homo sapiens (human) | Kd | 6.0151 | 4 | 5 |
| Serine/threonine-protein kinase PRP4 homolog | Homo sapiens (human) | Kd | 0.2200 | 1 | 1 |
| Serine/threonine-protein kinase receptor R3 | Homo sapiens (human) | Kd | 16.6667 | 3 | 3 |
| Serine/threonine-protein kinase RIO1 | Homo sapiens (human) | Kd | 0.1300 | 2 | 2 |
| Serine/threonine-protein kinase RIO2 | Homo sapiens (human) | Kd | 0.3900 | 1 | 1 |
| Serine/threonine-protein kinase RIO3 | Homo sapiens (human) | Kd | 0.0769 | 3 | 4 |
| Serine/threonine-protein kinase SBK1 | Homo sapiens (human) | Kd | 0.0032 | 1 | 1 |
| Serine/threonine-protein kinase Sgk3 | Homo sapiens (human) | Kd | 0.0034 | 1 | 1 |
| Serine/threonine-protein kinase SIK1 | Homo sapiens (human) | Kd | 0.0022 | 2 | 2 |
| Serine/threonine-protein kinase SIK2 | Homo sapiens (human) | Kd | 7.5150 | 3 | 4 |
| Serine/threonine-protein kinase SIK3 | Homo sapiens (human) | Kd | 11.3425 | 2 | 3 |
| Serine/threonine-protein kinase STK11 | Homo sapiens (human) | Kd | 15.0305 | 3 | 4 |
| Serine/threonine-protein kinase TAO1 | Homo sapiens (human) | Kd | 16.2525 | 2 | 3 |
| Serine/threonine-protein kinase TAO2 | Homo sapiens (human) | Kd | 20.0040 | 2 | 3 |
| Serine/threonine-protein kinase TAO3 | Homo sapiens (human) | Kd | 20.0001 | 2 | 3 |
| Serine/threonine-protein kinase TBK1 | Homo sapiens (human) | Kd | 10.3860 | 2 | 3 |
| Serine/threonine-protein kinase TNNI3K | Homo sapiens (human) | Kd | 1.0000 | 2 | 2 |
| Serine/threonine-protein kinase tousled-like 1 | Homo sapiens (human) | Kd | 0.0270 | 2 | 2 |
| Serine/threonine-protein kinase tousled-like 2 | Homo sapiens (human) | Kd | 0.0160 | 2 | 2 |
| Serine/threonine-protein kinase ULK1 | Homo sapiens (human) | Kd | 20.0033 | 2 | 3 |
| Serine/threonine-protein kinase ULK2 | Homo sapiens (human) | Kd | 0.0008 | 1 | 1 |
| Serine/threonine-protein kinase ULK3 | Homo sapiens (human) | Kd | 15.0270 | 2 | 4 |
| Serine/threonine-protein kinase ULK3 | Mus musculus (house mouse) | Kd | 0.0030 | 1 | 1 |
| Serine/threonine-protein kinase VRK2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Serine/threonine-protein kinase/endoribonuclease IRE1 | Homo sapiens (human) | Kd | 10.0133 | 2 | 3 |
| Serine/threonine-protein kinase/endoribonuclease IRE2 | Homo sapiens (human) | Kd | 15.4540 | 1 | 2 |
| Signal recognition particle receptor subunit alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 1 |
| SNF-related serine/threonine-protein kinase | Homo sapiens (human) | Kd | 0.0900 | 1 | 1 |
| Spike glycoprotein | Betacoronavirus England 1 | EC50 | 0.1055 | 1 | 4 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | EC50 | 0.1055 | 1 | 4 |
| SRSF protein kinase 1 | Homo sapiens (human) | Kd | 0.0055 | 2 | 2 |
| SRSF protein kinase 2 | Homo sapiens (human) | Kd | 0.0670 | 2 | 2 |
| SRSF protein kinase 3 | Homo sapiens (human) | Kd | 0.0730 | 1 | 1 |
| STE20-like serine/threonine-protein kinase | Homo sapiens (human) | Kd | 6.6610 | 4 | 5 |
| STE20-related kinase adapter protein alpha | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| STE20/SPS1-related proline-alanine-rich protein kinase | Homo sapiens (human) | Kd | 0.1300 | 1 | 1 |
| streptokinase A precursor | Streptococcus pyogenes M1 GAS | EC50 | 1.0393 | 2 | 3 |
| Structural maintenance of chromosomes protein 1A | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Structural maintenance of chromosomes protein 2 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Testis-specific serine/threonine-protein kinase 1 | Homo sapiens (human) | Kd | 0.0240 | 2 | 2 |
| TGF-beta receptor type-1 | Homo sapiens (human) | Kd | 9.0448 | 3 | 4 |
| TGF-beta receptor type-2 | Homo sapiens (human) | Kd | 20.0000 | 3 | 4 |
| Thyroid hormone receptor-associated protein 3 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| TRAF2 and NCK-interacting protein kinase | Homo sapiens (human) | Kd | 6.0051 | 4 | 5 |
| Transcriptional activator protein LasR | Pseudomonas aeruginosa PAO1 | EC50 | 0.0446 | 4 | 4 |
| Transient receptor potential cation channel subfamily M member 6 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | EC50 | 0.1055 | 1 | 4 |
| Tubulin alpha-1A chain | Rattus norvegicus (Norway rat) | Kd | 0.7700 | 1 | 1 |
| Tyrosine--tRNA ligase, cytoplasmic | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | Kd | 2.1908 | 30 | 31 |
| Tyrosine-protein kinase ABL2 | Homo sapiens (human) | Kd | 12.0760 | 4 | 5 |
| Tyrosine-protein kinase Blk | Homo sapiens (human) | Kd | 0.0150 | 2 | 2 |
| Tyrosine-protein kinase BTK | Homo sapiens (human) | Kd | 6.5394 | 4 | 5 |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | Kd | 12.2200 | 4 | 5 |
| Tyrosine-protein kinase Fer | Homo sapiens (human) | Kd | 6.1066 | 4 | 5 |
| Tyrosine-protein kinase Fes/Fps | Homo sapiens (human) | Kd | 15.0115 | 3 | 4 |
| Tyrosine-protein kinase Fgr | Homo sapiens (human) | Kd | 7.5160 | 4 | 4 |
| Tyrosine-protein kinase FRK | Homo sapiens (human) | Kd | 12.0700 | 4 | 5 |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | Kd | 12.0234 | 4 | 5 |
| Tyrosine-protein kinase HCK | Homo sapiens (human) | Kd | 12.0104 | 4 | 5 |
| Tyrosine-protein kinase ITK/TSK | Homo sapiens (human) | Kd | 0.0190 | 2 | 2 |
| Tyrosine-protein kinase JAK1 | Homo sapiens (human) | Kd | 16.0012 | 4 | 5 |
| Tyrosine-protein kinase JAK2 | Homo sapiens (human) | Kd | 7.5080 | 4 | 4 |
| Tyrosine-protein kinase JAK3 | Homo sapiens (human) | Kd | 0.0110 | 2 | 2 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | Kd | 12.0160 | 4 | 5 |
| Tyrosine-protein kinase Lyn | Homo sapiens (human) | Kd | 12.0580 | 4 | 5 |
| Tyrosine-protein kinase Mer | Homo sapiens (human) | Kd | 7.5134 | 3 | 4 |
| Tyrosine-protein kinase receptor Tie-1 | Homo sapiens (human) | Kd | 0.0650 | 2 | 2 |
| Tyrosine-protein kinase receptor TYRO3 | Homo sapiens (human) | Kd | 0.2800 | 2 | 2 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | Kd | 0.0068 | 2 | 2 |
| Tyrosine-protein kinase Srms | Homo sapiens (human) | Kd | 0.7400 | 2 | 2 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | Kd | 6.1160 | 4 | 5 |
| Tyrosine-protein kinase Tec | Homo sapiens (human) | Kd | 15.6500 | 3 | 4 |
| Tyrosine-protein kinase TXK | Homo sapiens (human) | Kd | 0.2300 | 2 | 2 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Kd | 12.0306 | 4 | 5 |
| Tyrosine-protein kinase ZAP-70 | Homo sapiens (human) | Kd | 0.0440 | 2 | 2 |
| U5 small nuclear ribonucleoprotein 200 kDa helicase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| UMP-CMP kinase | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Uncharacterized aarF domain-containing protein kinase 5 | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Uncharacterized protein FLJ45252 | Homo sapiens (human) | Kd | 15.0105 | 1 | 2 |
| Uncharacterized serine/threonine-protein kinase SBK3 | Homo sapiens (human) | Kd | 0.0250 | 1 | 1 |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | Kd | 0.1500 | 2 | 2 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | Kd | 0.2367 | 3 | 3 |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | Kd | 0.0290 | 3 | 3 |
| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial | Homo sapiens (human) | Kd | 30.0000 | 1 | 2 |
| Wee1-like protein kinase | Homo sapiens (human) | Kd | 15.8000 | 3 | 4 |
| Wee1-like protein kinase 2 | Homo sapiens (human) | Kd | 10.0000 | 1 | 1 |