tetracycline and Pelvic-Inflammatory-Disease

Nongonococcal urethritis is a venereal disease whose incidence is almost double that of gonorrhea. Despite this, the diagnosis, origin, treatment, and complications of nongonococcal urethritis remain unclear. Although some cases are undoubtedly caused by infection with Chlamydia trachomatis, the origin of many cases is uncertain. Treatment is recommended to shorten symptoms and prevent complications. This review presents the current status of this confusing disease.

Topics: Adolescent; Adult; Epididymitis; Female; Gonorrhea; Humans; Infant; Male; Mycoplasma Infections; Neisseria gonorrhoeae; Pelvic Inflammatory Disease; Pneumonia; Sexually Transmitted Diseases; Tetracycline; Trachoma; Urethritis

Topics: Abortion, Septic; Anticoagulants; Bacterial Infections; Bacteroides Infections; Chloramphenicol; Clindamycin; Clostridium Infections; Cross Infection; Drug Resistance, Microbial; Female; Genital Diseases, Female; Humans; Lincomycin; Pelvic Inflammatory Disease; Pregnancy; Pregnancy Complications, Infectious; Tetracycline; Thrombophlebitis

Topics: Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Colistin; Drug Hypersensitivity; Enterobacteriaceae Infections; Erythromycin; Female; Gonorrhea; Humans; Kidney Diseases; Mycoplasma Infections; Pelvic Inflammatory Disease; Salpingitis; Staphylococcal Infections; Streptococcal Infections; Streptomycin; Tetracycline; Thrombophlebitis; Tuberculosis, Female Genital; Wound Infection

The significance of C-reactive protein (CRP) in assessing the treatment of pelvic inflammatory disease (PID) was established and compared with body temperature (BT), erythrocyte sedimentation rate (ESR) and serum leukocyte concentration (L).. In 51 patients with PID, 20 (39%) of them with tubo-ovarial abscess (TOA), measurement of BT and laboratory investigations were carried out on admission and during treatment on days 3-4, 6-8 and 18-21. The changes in these values were compared with the changes in clinical condition.. Prior to treatment, the majority--49 patients or 96.1%--had increased CRP values. In successful treatment, the CRP values decreased significantly in PID patients without TOA on day 3-4, in patients with TOA on day 6-8 and reached normal values in both groups on day 18-21. Changes in clinical condition were most concurrent with changes in CRP.. In assessing PID treatment, the determination of CRP has precedence over L, ESR and BT as the percentage of patients with increased CRP is higher and because the changes in value follow the changes in clinical condition more reliably.

Topics: Abscess; Adult; Blood Sedimentation; Body Temperature; C-Reactive Protein; Ceftriaxone; Clindamycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Gentamicins; Humans; Oophoritis; Pelvic Inflammatory Disease; Prognosis; Prospective Studies; Salpingitis; Sensitivity and Specificity; Severity of Illness Index; Tetracycline

110 patients suffering from laparoscopical verified salpingitis and desire for a baby, were treated with tetracycline (oxytetracycline or doxycycline; TC)/metronidazole (n = 67), augmentan (n = 22) or cipropfloxacin/metronidazole (n = 21). After an average period of 11.6 weeks, all patients underwent second-look laparoscopy with dye insufflation. In 34 patients treated with TC/metronidazole, the effects of additional physio-therapeutical measures were examined under conditions as they prevail in a Spa. 33 patients without balneotherapy served as controls. All the 4 groups were comparable (p greater than 0.05) in respect of mean age, percentage, share of nulliparous women, salpingitis gonorrhoica, contraceptive behaviour and also of the stage of salpingitis. All antibiotic regimens used resulted in a prompt decrease of inflammatory clinical signs after five days (temperature, blood sedimentation rate, leukocytes). Only 2 of 34 patients treated by additional cure at a Spa reported complaints, whereas complaints were reported by 14 of 33 control patients (p less than 0.01), 7 of 22 (p less than 0.01) treated with augmentan and to 7 of 21 (p less than 0.01) treated with ciprofloxacin/metronidazole. The tubal occlusion rates amounted to 33.3% (TC/metronidazole), 32.3% (TC/metronidazole and balneotherapy), 22.7% (augmentan) and 23.8% ciprofloxacin/metronidazole. The differences did not attain statistical significance (p greater than 0.05). With regard to adhesions, there were, likewise, no significant differences between findings at first laparoscopy and second look-laparoscopy, respectively. It is concluded, that additional physiotherapeutic measures, after antibiotic therapy of acute salpingitis, reduce the frequency of lower abdominal pain, but do not result in an improvement of tubal occlusion and reduction of adhesions.(ABSTRACT TRUNCATED AT 250 WORDS)

Topics: Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Balneology; Clavulanic Acids; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Laparoscopy; Metronidazole; Pelvic Inflammatory Disease; Prospective Studies; Recurrence; Reoperation; Salpingitis; Tetracycline

We evaluated the effect of treatment of gonorrhea on simultaneous Chlamydia trachomatis infection by randomly assigning 293 heterosexual men and 246 heterosexual women with gonorrhea to receive one of the following treatment regimens: (1) 4.8 million units of aqueous procaine penicillin plus 1 g of probenecid, (2) nine tablets of trimethoprim-sulfamethoxazole daily for three days, or (3) 500 mg of tetracycline four times a day for five days. Among the men, gonococcal infection was cured in 99 per cent given penicillin plus probenecid, 96 per cent given trimethoprim-sulfamethoxazole, and 98 per cent given tetracycline. Among the women, only 90 per cent given tetracycline were cured, in contrast to 97 per cent given penicillin plus probenecid and 99 per cent given trimethoprim-sulfamethoxazole. Chlamydial infection, present in 15 per cent of the men and 26 per cent of the women, was cured in 30 of 32 patients given trimethoprim-sulfamethoxazole and 27 of 29 given tetracycline, but in only 10 of 23 given penicillin plus probenecid. Among chlamydia-positive patients, postgonococcal urethritis in men and cervicitis in women occurred more often in patients given penicillin plus probenecid. Salpingitis developed in 6 of 20 women given penicillin plus probenecid, but in only 1 of 26 given trimethoprim-sulfamethoxazole and in none of 24 given tetracycline. We conclude that the use of penicillin plus probenecid alone for gonorrhea in heterosexual patients carries an unacceptably high risk of postgonococcal chlamydial morbidity. Trimethoprim-sulfamethoxazole and tetracycline were highly effective against both pathogens and were well tolerated in men, but both drugs caused frequent side effects in women. The failure of tetracycline to cure gonorrhea in 10 per cent of women argues against its use alone; treatment with penicillin followed by tetracycline has been recommended for further trial.

Topics: Adolescent; Clinical Trials as Topic; Drug Administration Schedule; Drug Combinations; Female; Gonorrhea; Humans; Lymphogranuloma Venereum; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Probenecid; Random Allocation; Sex Factors; Sulfamethoxazole; Tetracycline; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Urethritis; Uterine Cervicitis

Topics: Female; Follow-Up Studies; Gonorrhea; Humans; Kenya; Length of Stay; Male; Neisseria gonorrhoeae; Oxyphenbutazone; Pain; Pelvic Inflammatory Disease; Placebos; Tetracycline; Urethra; Uterine Cervical Diseases

Topics: Adult; Chymotrypsin; Clinical Trials as Topic; Female; Humans; Middle Aged; Pelvic Inflammatory Disease; Ribonucleases; Tetracycline; Trypsin

54 patients presented by history, physical examination and laboratory tests with suspected pelvic inflammatory disease (PID). The use of laparoscopy as a diagnostic tool proved in 13 cases (24%) that the presumptive diagnosis was incorrect. Bacteriological studies revealed chlamydial infection in 21 of 41 cases, in 6 cases only at laparoscopy in the pelvic cavity, gonococcal in 9 of 41 cases; mycoplasmas were identified in 15 cases, being the only pathogen in 7. In 9 cases, no recognized pathogens were isolated. Polymicrobism was frequent. Follow-up studies identified 5 cases of treatment failure; 2 of Gonococcus and 3 of Chlamydia, and detected 3 cases of Chlamydia which had not been identified initially. We discuss the use of laparoscopy in the diagnosis and for follow-up and treatment of PIDs.

Topics: Acute Disease; Adult; Ampicillin; Chlamydia Infections; Drug Therapy, Combination; Female; Gonorrhea; Humans; Laparoscopy; Metronidazole; Mycoplasma Infections; Netilmicin; Pelvic Inflammatory Disease; Penicillin G Procaine; Tetracycline; Tobramycin

Clinical criteria and treatment protocols are outlined for 663 cases of mild, moderate and severe pelvic inflammatory disease (PID). Data on 176 patients requiring admission to hospital and who were treated conservatively with antibiotics are analysed. Criteria for operative intervention are outlined; only 1 patient required surgical intervention. The study suggests that, provided strict criteria are adhered to, conservative management of PID is both safe and effective and offers outlying hospitals and rural practitioners a plan of management that can be safely followed before resorting to referral to major centres.

Topics: Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Metronidazole; Oxytetracycline; Pelvic Inflammatory Disease; Penicillin G; Prospective Studies; Tetracycline; Tobramycin

Three treatment regimens are currently recommended for penicillin-susceptible Neisseria gonorrhoeae infection of the cervix: ampicillin, tetracycline, and a combination of ampicillin and tetracycline. To evaluate the cost-effectiveness of these options, we developed a decision analysis model and analyzed the efficacy of each treatment in curing gonorrhea, as well as coexisting Chlamydia trachomatis infection, and in preventing subsequent pelvic inflammatory disease, ectopic pregnancy, and infertility. We included direct costs of medication and expenditures for management of unresolved infections and associated complications. Combination treatment is more than twice as cost-effective as tetracycline and seven times as cost-effective as ampicillin when the medical cost of managing pelvic inflammatory disease is considered. When the costs of ectopic pregnancies and infertility are included, the cost-effectiveness of combination treatment increases further.

Topics: Ampicillin; Chlamydia Infections; Chlamydia trachomatis; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Gonorrhea; Humans; Infertility, Female; Pelvic Inflammatory Disease; Pregnancy; Pregnancy, Ectopic; Tetracycline; Uterine Cervicitis

Topics: beta-Lactamases; Ceftriaxone; Doxycycline; Drug Resistance, Microbial; Endophthalmitis; Female; Gonorrhea; Humans; Infant, Newborn; Information Systems; Neisseria gonorrhoeae; Pelvic Inflammatory Disease; Population Surveillance; Tetracycline; United States

A total of 40 patients with acute pelvic inflammatory disease (APID) were studied over a period of 7 months; one aim was to evaluate the use of different antibiotics in treatment. The most important findings were: (i) most patients had a polymicrobial aetiology for their APID; (ii) Chlamydia trachomatis and the anaerobic bacteria were the most common organisms encountered; and (iii) tetracycline plus metronidazole is probably the best combination therapy for APID.

Topics: Ampicillin; Anti-Bacterial Agents; Doxycycline; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Metronidazole; Oxytetracycline; Pelvic Inflammatory Disease; Random Allocation; Tetracycline

Four cases of the Curtis-Fitz-Hugh syndrome diagnosed laparoscopically and with microbiological or serological evidence of chlamydial pelvic infection are reviewed. The case histories emphasize the part played by renal angle and left upper quadrant symptoms. In one patient the surface of the spleen was affected by the same classical inflammation normally seen on the surface of the liver. In 3 patients bilateral or left-sided renal angle pain and tenderness constituted the presenting features, or a major manifestation, and in all patients renal tract investigations were entirely normal. The patient with laparoscopic perisplenitis also had perihepatitis and pelvic inflammation, the latter being florid in all cases. Perisplenitis and perinephritis are proposed as possible additional manifestations of this syndrome.

Topics: Adolescent; Adult; Chlamydia Infections; Chlamydia trachomatis; Female; Hepatitis; Humans; Pelvic Inflammatory Disease; Perinephritis; Peritonitis; Splenic Diseases; Syndrome; Tetracycline

Recent guidelines issued by the Centers for Disease Control discuss prevention and control of Chlamydia trachomatis infection. Chlamydia trachomatis is the commonest sexually transmitted infection in the United States. The rate of infection has increased in the past 10 years. The guidelines do not discuss control of trachoma and only briefly discuss lymphogranuloma venereum. Education of health care professionals and the public about C. trachomatis is recommended, along with the establishment of a nationwide surveillance system.

Topics: Adolescent; Adult; Anti-Bacterial Agents; Centers for Disease Control and Prevention, U.S.; Chlamydia Infections; Chlamydia trachomatis; Doxycycline; Female; Humans; Infant; Infant, Newborn; Male; Pelvic Inflammatory Disease; Pregnancy; Sexually Transmitted Diseases; Tetracycline; United States

A retrospective chart review was conducted of all patients with pelvic inflammatory disease (PID) during 1980 at an inner-city neighborhood health center. The presenting clinical features, laboratory results, management, and recurrences within a 6-18 month follow-up were analyzed. PID was diagnosed in 264 patients, 60 (23%) of whom were less than 21 years old. Pelvic organ tenderness was present in all patients. Three percent had an elevated white blood cell count and/or erythrocyte sedimentation rate. Four percent were hospitalized. Ten percent had positive endocervical cultures for N. gonorrhoeae. Six percent of the records included treatment plans for the male contact. Twenty-seven percent had a recurrence of PID. The lack of criteria for diagnosing PID and the inconsistencies in its management are discussed. Recommendations for the management of cervicitis and male contacts are presented.

Topics: Adolescent; Adult; Age Factors; Ambulatory Care; Ampicillin; Erythromycin; Female; Follow-Up Studies; Gonorrhea; Humans; Neisseria gonorrhoeae; New York; Pelvic Inflammatory Disease; Recurrence; Tetracycline

Topics: Actinomycosis; Female; Intrauterine Devices; Pelvic Inflammatory Disease; Penicillins; Tetracycline; Vaginal Smears

The records of 1,381 patients with gonorrhea were examined by the Massachusetts Department of Public Health to determine the efficacy of their treatment schedules. Urethritis, cervicitis and pharyngitis were treated with 4.8 million u. of aqueous procaine penicillin G intramuscularly, without probenecid. Cure rates were 98 percent in urethritis, 97 percent in pharyngitis and 98 percent in cervicitis. Patients allergic to penicillin were treated with tetracycline orally or spectinomycin intramuscularly. In patients with proctitis, a 98 percent cure rate was achieved with one intramuscular injection of procaine penicillin G, followed by ampicillin orally for four days.

Topics: Adult; Ampicillin; Drug Administration Schedule; Female; Gonorrhea; Humans; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Penicillin Resistance; Pharyngitis; Proctitis; Spectinomycin; Tetracycline; Urethritis; Uterine Cervicitis

Chlamydiae are obligate intracellular parasites, bacteria with a peculiar biology. They belong to the genus Chlamydia which includes two species: C. psittaci and C. trachomatis. A wide range of hosts, including birds, mammals and man can be infected by chlamydiae. The diseases chlamydiae can produce include psittacosis, lymphogranuloma venereum, trachoma, inclusion conjunctivitis, urethritis, cervicitis, pelvic inflammatory disease, and neonatal pneumonia. The diagnosis of chlamydial infection may be made by visualization of the organism in direct smears, isolation of the agent in cell culture, or by demonstrating a significant rise in antibody titer. Chlamydial infection may be treated with tetracycline, erythromycin, or sulfonamides.

Topics: Adult; Arthritis, Reactive; Child; Chlamydia Infections; Conjunctivitis, Inclusion; Epididymitis; Erythromycin; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lymphogranuloma Venereum; Male; Pelvic Inflammatory Disease; Pneumonia; Sexually Transmitted Diseases; Tetracycline; Trachoma; Urethritis; Uterine Cervicitis

Topics: Adolescent; Adult; Amphotericin B; Bacterial Infections; Candidiasis, Vulvovaginal; Drug Combinations; Female; Genital Diseases, Female; Humans; Middle Aged; Pelvic Inflammatory Disease; Suppositories; Tetracycline; Vaginitis

Although previous large series have reported that from 0.3% to 1.3% of patients undergoing hysterosalpingography (HSG) develop infectious morbidity, our impression was that the incidence was higher among our patients. Therefore the records of 448 consecutive healthy women who underwent HSG were examined. Within 24 hours after the HSG, 14 of these 448 patients (3.1%) developed fever and pelvic peritonitis requiring hospitalization and treatment with parenteral antibiotics, a significantly greater frequency than reported elsewhere (P less than 0.01). Traditional laboratory tests failed to predict patients at risk, and prophylactic antibiotics effective against aerobic organisms could not protect against this complication. However, it was possible to design a scoring system based on specific findings in the history and previous physical examinations that was capable of identifying patients who would subsequently become infected. The clinical sensitivity of this scoring technique is 57%, clinical specificity 99%, and test efficiency 97%. It is suggested that in view of the major risk of post-HSG infection in certain identifiable women and because of the impact of this complication on their future fertility, hysterosalpingography should not be performed in those patients determined to be at high risk. In women at lowest risk, the procedure is safe. Finally, in patients assigned an intermediate risk-score, the risk-benefit ratio must be carefully weighed and discussed with the patient, and prophylactic antibiotics with anaerobic coverage should be considered.

Topics: Adolescent; Adult; Aminoglycosides; Ampicillin; Blood Sedimentation; Cephalosporins; Female; Fever; Humans; Hysterosalpingography; Leukocyte Count; Middle Aged; Pelvic Inflammatory Disease; Penicillins; Risk; Tetracycline

Topics: Chronic Disease; Female; Follow-Up Studies; Humans; Iontophoresis; Pelvic Inflammatory Disease; Procaine; Sulfonamides; Tetracycline

We have briefly presented practical approaches to the management of the most common disorders caused by sexually transmitted pathogens, including pelvic inflammatory disease, urethritis in men, genital lesions, vaginal discharge, and syphilis. Guidelines for the management of gonorrhea may change if penicillin-resistant strains become more prevalent. Areas which require further research include the treatment of genital herpes and the prevention of recurrences, the treatment of nonspecific vaginitis, and definition of the importance of metronidazole toxicity.

Topics: Anti-Bacterial Agents; Candidiasis, Vulvovaginal; Female; Genital Diseases, Female; Genital Diseases, Male; Gonorrhea; Herpesviridae Infections; Humans; Male; Pelvic Inflammatory Disease; Penicillin G; Pharyngeal Diseases; Pregnancy; Sexually Transmitted Diseases; Syphilis; Tetracycline; Urethritis; Vaginitis

To evaluate guidelines for outpatient treatment of acute pelvic inflammatory disease recommended by the Center for Disease Control we studied 197 afflicted women. The women were treated either with tetracycline or with procaine penicillin and ampicillin, and 92% were subsequently seen at least once to assess efficacy of clinical and microbiologic treatment. Neisseria gonorrhoeae was isolated from the lower genital tract in 68% of these women, and although they had a quicker symptomatic response than those with nongonococcal infection (P less than 0.01), the two regimens were equally effective in producing clinical cure. However, subsequent identification of a pelvic abscess was 10 times more common in women from whom N. gonorrhoeae was not isolated. Therapy for pelvic inflammatory disease must be empirical since it is impossible to distinguish clinically between gonococcal and nongonococcal infection, and our data indicate that both regimens recommended by the Center for Disease Control are effective.

Topics: Acute Disease; Adult; Ampicillin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Injections, Intramuscular; Neisseria gonorrhoeae; Pelvic Inflammatory Disease; Penicillin G Procaine; Probenecid; Tetracycline

Topics: Ambulatory Care; Ampicillin; Bacterial Infections; Bacteroides fragilis; Female; Gram-Negative Anaerobic Bacteria; Humans; Pelvic Inflammatory Disease; Tetracycline

One hundred emergency department charts on cases of suspected pelvic inflammatory disease (PID) were reviewed to determine method of diagnosis and treatment. Seventy-three gonococcus smears, 60 gonococcus cultures, and 53 VDRL tests for syphilis were done. Of these, 20 smears, 19 cultures, and 1 VDRL were positive. All 100 patients were treated for gonorrhea with either spectinomycin, tetracycline, ampicillin or penicillin. The author concludes there is no need to procure VDRL tests on all patients with suspected gonorrhea, nor do gonococcus cultures on all patients with suspected PID. Also, since only 39% of patients had a positive gonococcus smear or culture, penicillin may not always be the appropriate treatment.

Topics: Ampicillin; Emergency Service, Hospital; Female; Gonorrhea; Humans; Pelvic Inflammatory Disease; Penicillins; Spectinomycin; Tetracycline

Topics: Ampicillin; Child; Female; Gonorrhea; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Pharyngitis; Probenecid; Spectinomycin; Syphilis; Tetracycline; United States; United States Public Health Service; Urethritis

Topics: Adolescent; Adult; Chronic Disease; Drug Combinations; Drug Therapy, Combination; Female; Gonorrhea; Humans; Immunotherapy; Middle Aged; Oleandomycin; Pelvic Inflammatory Disease; Prodigiosin; Tetracycline; Trichomonas Infections; Urethritis; Uterine Cervicitis

Topics: Candidiasis, Vulvovaginal; Female; Gonorrhea; Humans; Male; Pelvic Inflammatory Disease; Penicillin G Procaine; Pharyngitis; Proctitis; Syphilis; Tetracycline; Urogenital System; Vulvovaginitis

Topics: Acute Disease; Adolescent; Adult; Bromelains; Chronic Disease; Drug Combinations; Female; Genital Diseases, Female; Humans; Middle Aged; Parametritis; Pelvic Inflammatory Disease; Peritonitis; Salpingitis; Tetracycline

Topics: Chronic Disease; Endometritis; Female; Genital Diseases, Female; Humans; Inflammation; Oophoritis; Pelvic Inflammatory Disease; Pyrazoles; Salpingitis; Tetracycline

Topics: Adult; Escherichia coli; Female; Genital Diseases, Female; Humans; Microbial Sensitivity Tests; Middle Aged; Pelvic Inflammatory Disease; Peritonitis; Pregnancy; Pregnancy Complications, Infectious; Tetracycline; Urinary Tract Infections

Topics: Adult; Amniotic Fluid; Cystitis; Escherichia coli; Female; Genital Diseases, Female; Genitalia, Female; Humans; Microbial Sensitivity Tests; Middle Aged; Milk, Human; Pelvic Inflammatory Disease; Peritonitis; Pyelonephritis; Surgical Wound Infection; Tetracycline; Umbilical Cord; Uterine Diseases; Vulvitis

Topics: Adult; Fallopian Tubes; Female; Genital Diseases, Female; Humans; Middle Aged; Milk, Human; Ovary; Pelvic Inflammatory Disease; Postpartum Period; Pregnancy; Tetracycline; Uterus

Topics: Adolescent; Adult; Anti-Inflammatory Agents; Bronchitis; Child; Enteritis; Female; Humans; Inflammation; Male; Middle Aged; Nephritis; Otitis; Pelvic Inflammatory Disease; Phlebitis; Pyelitis; Pyrazoles; Sinusitis; Tetracycline; Tonsillitis

Topics: Adolescent; Adult; Chymotrypsin; Female; Guaifenesin; Humans; Male; Middle Aged; Pelvic Inflammatory Disease; Respiratory Tract Infections; Tetracycline; Trypsin; Uterine Cervicitis

Topics: Adolescent; Adult; Aged; Chymotrypsin; Female; Guaifenesin; Humans; Male; Middle Aged; Pelvic Inflammatory Disease; Peritonitis; Respiratory Tract Infections; Tetracycline; Trypsin

Topics: Amines; Anti-Inflammatory Agents; Drug Synergism; Female; Genital Diseases, Female; Humans; Mastitis; Oxazines; Pelvic Inflammatory Disease; Peritonitis; Pregnancy; Puerperal Infection; Tetracycline; Vulvitis

Topics: Chloramphenicol; Female; Humans; Muramidase; Pelvic Inflammatory Disease; Tetracycline

Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Female; Fertility; Humans; Infertility; Infertility, Male; Male; Pelvic Inflammatory Disease; Penicillins; Protein Synthesis Inhibitors; Spermatozoa; Streptomycin; Tetracycline; Uterine Cervicitis

Topics: Anti-Bacterial Agents; Cortisone; Disease; Female; Humans; Pelvic Inflammatory Disease; Pelvis; Tetracycline

Topics: Anti-Bacterial Agents; Chronic Disease; Cortisone; Disease; Female; Humans; Pelvic Inflammatory Disease; Pelvis; Tetracycline