Page last updated: 2024-08-05 15:15:51

molluscicide

A substance used to destroy pests of the phylum Mollusca.

ChEBI ID: 33904

Members (8)

MemberDefinitionClass
aminocarbA carbamate ester that is phenyl methylcarbamate substituted by a dimethylamino group at position 4 and a methyl group at position 3.aminocarb
chloroxylenolA member of the class of phenols that is 3,5-xylenol which is substituted at position 4 by chlorine. It is bactericidal against most Gram-positive bacteria but less effective against Staphylococci and Gram-negative bacteria, and often inactive against Pseudomonas species. It is ineffective against bacterial spores.4-chloro-3,5-dimethylphenol
cuprous chlorideAn inorganic chloride of copper in which the metal is in the +1 oxidation state.copper(I) chloride
cypermethrinA carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.cypermethrin
dioncophylline aAn isoquinoline alkaloid that is the biaryl resulting from substitution of the hydrogen at the 7-position of (1R,3R)-1,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-8-ol by a 4,5-dimethoxy-2-methylnaphthalen-1-yl group. It is a naphthylisoquinoline alkaloid isolated from the roots and stem barks of Triphyophyllum peltatum and exhibits antifungal, antimalarial, antineoplastic and molluscicidal activites.7-epi-dioncophylline A; dioncophylline A
metaldehydeA member of the class of tetroxocanes that is 1,3,5,7-tetroxocane which carries four methyl groups at positions 2,4,6 and 8. It is a potent molluscicide and the active ingredient in most slug pellets used for crop protection.metaldehyde
methiocarbA carbamate ester obtained by the formal condensation of the phenolic group of 3,5-dimethyl-4-(methylsulfanyl)phenol with the carboxy group of methylcarbamic acid.methiocarb
niclosamideA secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.niclosamide

Research

Studies (2,987)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-1990492 (16.47)18.7374
1990's310 (10.38)18.2507
2000's568 (19.02)29.6817
2010's1,115 (37.33)24.3611
2020's502 (16.81)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials59 (1.82%)5.53%
Reviews94 (2.90%)6.00%
Case Studies108 (3.33%)4.05%
Observational2 (0.06%)0.25%
Other2,981 (91.89%)84.16%

Protein Targets (175)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
15-lipoxygenase, partialHomo sapiens (human)Potency39.810711
67.9K proteinVaccinia virusPotency1.595422
acetylcholinesteraseHomo sapiens (human)Potency10.610848
activating transcription factor 6Homo sapiens (human)Potency25.931313
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency24.165414
Alpha-synucleinHomo sapiens (human)Potency1.413713
AR proteinHomo sapiens (human)Potency20.75241021
aryl hydrocarbon receptorHomo sapiens (human)Potency11.789236
arylsulfatase AHomo sapiens (human)Potency37.933011
ATAD5 protein, partialHomo sapiens (human)Potency0.879233
Ataxin-2Homo sapiens (human)Potency5.472812
ATPase family AAA domain-containing protein 5Homo sapiens (human)Potency5.472812
atrial natriuretic peptide receptor 1 precursorHomo sapiens (human)Potency0.952811
atrial natriuretic peptide receptor 2 precursorHomo sapiens (human)Potency1.309211
Bloom syndrome protein isoform 1Homo sapiens (human)Potency19.952622
Cellular tumor antigen p53Homo sapiens (human)Potency6.412938
cellular tumor antigen p53 isoform aHomo sapiens (human)Potency2.622426
Chain A, Beta-lactamaseEscherichia coli K-12Potency5.623411
Chain A, CruzipainTrypanosoma cruziPotency5.623411
Chain A, Ferritin light chainEquus caballus (horse)Potency22.983322
Chain A, JmjC domain-containing histone demethylation protein 3AHomo sapiens (human)Potency70.794611
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency15.811411
Chain A, TYROSYL-DNA PHOSPHODIESTERASEHomo sapiens (human)Potency6.314612
chromobox protein homolog 1Homo sapiens (human)Potency39.810711
cytochrome P450 2C19 precursorHomo sapiens (human)Potency0.398111
cytochrome P450 2C9 precursorHomo sapiens (human)Potency1.571412
cytochrome P450 2C9, partialHomo sapiens (human)Potency10.537514
cytochrome P450 2D6Homo sapiens (human)Potency13.450411
cytochrome P450 2D6 isoform 1Homo sapiens (human)Potency31.622811
cytochrome P450 3A4 isoform 1Homo sapiens (human)Potency15.333428
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency16.013013
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency0.975012
D(1A) dopamine receptorHomo sapiens (human)Potency0.344522
D(1A) dopamine receptorSus scrofa (pig)Potency2.074911
DNA polymerase eta isoform 1Homo sapiens (human)Potency89.125111
DNA polymerase iota isoform a (long)Homo sapiens (human)Potency69.621912
DNA polymerase kappa isoform 1Homo sapiens (human)Potency59.976312
endonuclease IVEscherichia coliPotency11.220211
estrogen nuclear receptor alphaHomo sapiens (human)Potency16.42231022
estrogen receptor 2 (ER beta)Homo sapiens (human)Potency15.011523
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency14.11471025
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency15.529013
EWS/FLI fusion proteinHomo sapiens (human)Potency8.973444
farnesoid X nuclear receptorHomo sapiens (human)Potency11.308746
flap endonuclease 1Homo sapiens (human)Potency4.228411
Fumarate hydrataseHomo sapiens (human)Potency3.246812
GVesicular stomatitis virusPotency10.537514
GABA theta subunitRattus norvegicus (Norway rat)Potency15.333414
GALC proteinHomo sapiens (human)Potency0.316211
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)Potency15.333414
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)Potency15.333414
gemininHomo sapiens (human)Potency1.031548
GLI family zinc finger 3Homo sapiens (human)Potency8.4720210
glp-1 receptor, partialHomo sapiens (human)Potency1.584911
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency6.826445
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency35.139815
Guanine nucleotide-binding protein GHomo sapiens (human)Potency1.995311
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)Homo sapiens (human)Potency1.849311
heat shock protein beta-1Homo sapiens (human)Potency30.642125
Histamine H2 receptorCavia porcellus (domestic guinea pig)Potency1.218228
histone deacetylase 9 isoform 3Homo sapiens (human)Potency0.736024
Histone H2A.xCricetulus griseus (Chinese hamster)Potency70.268022
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency10.537514
huntingtin isoform 2Homo sapiens (human)Potency0.794311
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency61.644811
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)Homo sapiens (human)Potency2.253624
IDH1Homo sapiens (human)Potency14.729612
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency10.537518
Integrin alpha-IIbHomo sapiens (human)Potency3.417313
Integrin beta-3Homo sapiens (human)Potency3.417313
Interferon betaHomo sapiens (human)Potency10.537514
lamin isoform A-delta10Homo sapiens (human)Potency2.117825
lethal factor (plasmid)Bacillus anthracis str. A2012Potency0.376212
LuciferasePhotinus pyralis (common eastern firefly)Potency15.111446
M-phase phosphoprotein 8Homo sapiens (human)Potency79.432811
Microtubule-associated protein tauHomo sapiens (human)Potency5.120912
mitogen-activated protein kinase 1Homo sapiens (human)Potency0.501211
muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)Potency3.540622
nonstructural protein 1Influenza A virus (A/WSN/1933(H1N1))Potency3.548111
NPC intracellular cholesterol transporter 1 precursorHomo sapiens (human)Potency0.052412
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency23.2235310
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency29.092911
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency61.614611
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency7.498926
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency25.0267313
Ornithine decarboxylaseRattus norvegicus (Norway rat)Potency3.162311
parathyroid hormone/parathyroid hormone-related peptide receptor precursorHomo sapiens (human)Potency50.383412
ParkinHomo sapiens (human)Potency1.632612
peripheral myelin protein 22Rattus norvegicus (Norway rat)Potency9.323322
peripheral myelin protein 22 isoform 1Homo sapiens (human)Potency0.379311
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency1.188423
peroxisome proliferator-activated receptor deltaHomo sapiens (human)Potency3.497446
PINK1Homo sapiens (human)Potency1.632612
plasminogen precursorMus musculus (house mouse)Potency3.548111
polyproteinZika virusPotency3.246812
Polyunsaturated fatty acid lipoxygenase ALOX15BHomo sapiens (human)Potency0.158511
pregnane X nuclear receptorHomo sapiens (human)Potency30.297428
pregnane X receptorRattus norvegicus (Norway rat)Potency49.489212
progesterone receptorHomo sapiens (human)Potency21.604915
pyruvate kinaseLeishmania mexicana mexicanaPotency2.511922
pyruvate kinase PKM isoform bHomo sapiens (human)Potency3.162322
Rap guanine nucleotide exchange factor 4Homo sapiens (human)Potency79.432811
RAR-related orphan receptor gammaMus musculus (house mouse)Potency24.677826
ras-related protein Rab-9AHomo sapiens (human)Potency0.089712
regulator of G-protein signaling 4Homo sapiens (human)Potency16.833611
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency0.056636
retinoid X nuclear receptor alphaHomo sapiens (human)Potency14.816247
serine/threonine-protein kinase mTOR isoform 1Homo sapiens (human)Potency1.620822
SMAD family member 2Homo sapiens (human)Potency1.497224
SMAD family member 3Homo sapiens (human)Potency1.497224
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusPotency0.520922
survival motor neuron protein isoform dHomo sapiens (human)Potency10.774813
TAR DNA-binding protein 43Homo sapiens (human)Potency0.891311
TDP1 proteinHomo sapiens (human)Potency3.330928
thioredoxin reductaseRattus norvegicus (Norway rat)Potency0.005311
ThrombopoietinHomo sapiens (human)Potency0.100022
thyroid hormone receptor beta isoform 2Rattus norvegicus (Norway rat)Potency20.738827
thyroid hormone receptor beta isoform aHomo sapiens (human)Potency1.412511
thyroid stimulating hormone receptorHomo sapiens (human)Potency25.422846
TSHR proteinHomo sapiens (human)Potency92.537423
urokinase plasminogen activator surface receptor precursorMus musculus (house mouse)Potency3.548111
urokinase-type plasminogen activator precursorMus musculus (house mouse)Potency3.548111
USP1 protein, partialHomo sapiens (human)Potency59.664912
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency50.799224
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency5.044247
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency35.139815

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)IC5083.900011
5-hydroxytryptamine receptor 2BHomo sapiens (human)IC501.856011
5-hydroxytryptamine receptor 2BHomo sapiens (human)Ki1.181011
Amine oxidase [flavin-containing] AHomo sapiens (human)IC501.829011
Angiopoietin-1 receptorHomo sapiens (human)IC5067.800011
Angiotensin-converting enzyme 2 Homo sapiens (human)IC5050.000011
Anoctamin-1Homo sapiens (human)IC500.028011
Aurora kinase AHomo sapiens (human)IC5054.100011
Bile salt export pumpHomo sapiens (human)IC50129.900011
Epidermal growth factor receptorHomo sapiens (human)IC5010.500011
Fibroblast growth factor receptor 1Homo sapiens (human)IC5013.100011
glucose-6-phosphate 1-dehydrogenase isoform bHomo sapiens (human)IC5080.000011
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium bergheiIC5057.900033
Glycogen synthase kinase-3 betaHomo sapiens (human)IC5077.500011
Mast/stem cell growth factor receptor KitHomo sapiens (human)IC5027.800011
Mitogen-activated protein kinase 1Homo sapiens (human)IC50100.000011
Mitogen-activated protein kinase 8Homo sapiens (human)IC50100.000011
Platelet-derived growth factor receptor betaHomo sapiens (human)IC50100.000011
Procathepsin LHomo sapiens (human)IC5050.000011
Protein kinase C alpha typeHomo sapiens (human)IC50100.000011
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)IC5010.250022
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)IC5059.400011
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)IC50100.000011
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirusIC5050.000022
Replicase polyprotein 1abBetacoronavirus England 1IC5050.000011
Replicase polyprotein 1abHuman coronavirus 229EIC5050.000022
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 2IC5030.093333
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirusIC5046.000055
Serine/threonine-protein kinase B-rafHomo sapiens (human)IC50100.000022
Signal transducer and activator of transcription 3Homo sapiens (human)IC500.230022
Spike glycoproteinBetacoronavirus England 1IC5050.000011
Spike glycoproteinSevere acute respiratory syndrome-related coronavirusIC5050.000011
Transmembrane protease serine 2Homo sapiens (human)IC5050.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)IC50100.000011
Tyrosine-protein kinase JAK2Homo sapiens (human)IC5055.000022
Tyrosine-protein kinase LynHomo sapiens (human)IC5023.800011
Vascular endothelial growth factor receptor 2Homo sapiens (human)IC5023.100011