Any compound that is able to prevent damage to the liver.
| Member | Definition | Class |
|---|
| 1-deoxynojirimycin | An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. | duvoglustat |
| 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose | A galloyl-beta-D-glucose compound having five galloyl groups in the 1-, 2-, 3-, 4- and 6-positions. | 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose |
| 5-methoxypsoralen | A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5. | 5-methoxypsoralen |
| agathisflavone | A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-6 and C-8 of the two chromene rings. | agathisflavone |
| aurapten | A member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties. | auraptene |
| avicularin | A quercetin O-glycoside in which an alpha-L-arabinofuranosyl residue is attached at position 3 of quercetin via a glycosidic linkage. It is isolated particularly from Juglans regia and Foeniculum vulgare. | avicularin |
| azadirachtin | A member of the family of azadirachtins that is isolated from the neem tree (Azadirachta indica). | azadirachtin A |
| brazilin | A organic heterotetracyclic compound that is a red pigment obtained from the wood of Caesalpinia echinata (Brazil-wood) or Caesalpinia sappan (sappan-wood). | brazilin |
| chrysin | A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7. | chrysin |
| columbianadin | An alpha,beta-unsaturated carboxylic ester obtained by formal condensation of the carboxy group of angelic acid with the hydroxy group of 2-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h][1]benzopyran-8-yl]propan-2-ol. | columbianadin |
| corynoline | A benzophenanthridine alkaloid that is chelidonine substituted by a methyl group at position 13. Isolated from the aerial parts of Corydalis incisa, it acts as an acetylcholinesterase inhibitor and also exhibits antineoplastic and hepatoprotective activity. | corynoline |
| curcumin | A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. | curcumin |
| dieckol | A phlorotannin isolated from a brown alga Ecklonia cava which exhibits antioxidant, hepatoprotective and anticoagulant activities. | dieckol |
| dioscin | A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage. | dioscin |
| ebselen | A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase. | ebselen |
| forapin | A 26-membered polypeptide consisting of Gly, Ile, Gly, Ala, Val, Leu, Lys, Val, Leu, Thr, Thr, Gly, Leu, Pro, Ala, Leu, Ile, Ser, Trp, Ile, Lys, Arg, Lys, Arg, Gln and Gln-NH2 residues joined in sequence. It is the principal active component of bee venom. | melittin |
| fraxetin | A hydroxycoumarin that is 6-methoxycoumarin in which the hydrogens at positions 7 and 8 have been replaced by hydroxy groups. | fraxetin |
| fraxin | A beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo. | fraxin |
| gamma-tocotrienol | A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2, 7 and 8 and a farnesyl chain at position 2. A vitamin E family member that has potent anti-cancer properties against a wide-range of cancers. | gamma-tocotrienol |
| ganodermadiol | A tetracyclic triterpenoid that is lanosta-7,9(11),24-triene which is substituted by hydroxy groups at positions 3 and 27. It has been isolated from several Ganoderma species. | ganoderol B |
| germacrone | A germacrane sesquiterpenoid that has formula C15H22O. It is a natural product found in traditional medicinal plants of the family Zingiberaceae. The compound exhibits a range of pharmacological activities including anti-inflammatory, anticancer, antiviral, anti-androgenic, antioxidant, antimicrobial, antifungal, neuroprotective and insecticidal activities. | (E,E)-germacrone |
| ginsenoside m1 | A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 20 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. | ginsenoside C-K |
| ginsenoside rh2 | A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy group at position 3 has been converted to the corresponding beta-D-glucopyranoside, and in which a double bond has been introduced at the 24-25 position. | (20S)-ginsenoside Rh2 |
| glycine | The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. | glycine zwitterion; glycine |
| glycyl-histidyl-lysine | A tripeptide composed of glycine, L-histidine and L-lysine residues joined in sequence. | Gly-His-Lys |
| grazoprevir | An azamacrocyclic compound that is a hepatitis C protease inhibitor used in combination with elbasvir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults. | grazoprevir |
| hyperoside | A quercetin O-glycoside that is quercetin with a beta-D-galactosyl residue attached at position 3. Isolated from Artemisia capillaris, it exhibits hepatoprotective activity. | quercetin 3-O-beta-D-galactopyranoside |
| isobutrin | A member of the class of chalcones that is trans-chalcone substituted by beta-D-glucopyranosyloxy groups at positions 3 and 4' and hydroxy groups at positions 4 and 2' respectively. | isobutrin |
| kolaviron | A biflavonoid isolated from the seeds of Garcinia kola that has been shown to exhibit hepatoprotective activity. | kolaflavanone |
| mk-8742 | A complex organic heterotetracyclic compound that is a hepatitis C virus nonstructural protein 5A inhibitor used in combination with grazoprevir (under the brand name Zepatier) for treatment of chronic HCV genotypes 1 or 4 infection in adults. | elbasvir |
| morin | A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5. | morin |
| novobiocin | A coumarin-derived antibiotic obtained from Streptomyces niveus. | novobiocin |
| obeticholic acid | A dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis. | obeticholic acid |
| ornithine | An optically active form of ornithine having L-configuration. | L-ornithine |
| physcione | A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources. | physcion |
| polydatin | A stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue. | trans-piceid |
| protectin d1 | A dihydroxydocosahexaenoic acid that is (4Z,7Z,11E,13E,15Z,19Z)-docosahexaenoic acid in which the two hydroxy substituents are located at positions 10 and 17 (the 10R,17S-stereoisomer). Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1 | protectin D1 |
| raspberry ketone | A ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at position 4 by a hydroxy group. It is found in a variety of fruits including raspberries, blackberries and cranberries, and is used in perfumery and cosmetics. | raspberry ketone |
| rubiadin | A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 3 and a methyl group at position 2. It has been isolated from Rubia yunnanensis. | rubiadin |
| salvianolic acid B | A member of the class of 1-benzofurans that is an antioxidant and free radical scavenging compound extracted from S. miltiorrhiza | salvianolic acid B |
| schizandrin b | An organic heterotetracyclic compound that is found in Fructus Schisandrae and Schisandra chinensis. | (+)-schisandrin B; Deoxygomisin A |
| silybin | A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities. | silibinin |
| syringin | A monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. | syringin |
| tempol | A member of the class of aminoxyls that is TEMPO carrying a hydroxy substituent at position 4. It is a radical scavenger which exhibits anti-inflammatory and analgesic properties. | 4-hydroxy-TEMPO |
| theasinensin a | A biflavonoid that is obtained by coupling of two molecules of (-)-epigallocatechin 3-gallate resulting in a bond between positions C-2 of the hydroxyphenyl ring. It is a natural product found in oolong tea. | theasinensin A |
| thiazolidine-4-carboxylic acid | A sulfur-containing amino acid that is proline in which the methylene group at position 4 is replaced by a sulfur atom. | thioproline zwitterion; thioproline |
| tranilast | An amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. | tranilast |
| wedelolactone | A member of the class of coumestans that is coumestan with hydroxy substituents as positions 1, 8 and 9 and a methoxy substituent at position 3. | wedelolactone |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 20.0394 | 1 | 16 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 11.8807 | 1 | 8 |
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Leishmania major strain Friedlin | Potency | 7.5686 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 14.2513 | 2 | 4 |
| acetylcholinesterase | Homo sapiens (human) | Potency | 54.3797 | 4 | 6 |
| acid sphingomyelinase | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 35.6534 | 2 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 20.6453 | 1 | 23 |
| alpha-galactosidase | Homo sapiens (human) | Potency | 31.6380 | 3 | 6 |
| Alpha-synuclein | Homo sapiens (human) | Potency | 10.2284 | 1 | 5 |
| Amyloid-beta precursor protein | Homo sapiens (human) | Potency | 16.3601 | 1 | 1 |
| apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 10.1505 | 1 | 4 |
| AR protein | Homo sapiens (human) | Potency | 17.9432 | 10 | 53 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 21.0712 | 3 | 19 |
| arylsulfatase A | Homo sapiens (human) | Potency | 6.7456 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 11.7079 | 4 | 6 |
| Ataxin-2 | Homo sapiens (human) | Potency | 23.0784 | 2 | 4 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 16.0381 | 3 | 10 |
| ATPase family AAA domain-containing protein 5 | Homo sapiens (human) | Potency | 32.6018 | 2 | 6 |
| atrial natriuretic peptide receptor 1 precursor | Homo sapiens (human) | Potency | 8.1369 | 1 | 2 |
| atrial natriuretic peptide receptor 2 precursor | Homo sapiens (human) | Potency | 14.9057 | 1 | 2 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 17.5693 | 2 | 4 |
| BRCA1 | Homo sapiens (human) | Potency | 11.2202 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | Homo sapiens (human) | Potency | 57.8941 | 1 | 7 |
| C-terminal-binding protein 1 | Homo sapiens (human) | Potency | 16.9469 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | Homo sapiens (human) | Potency | 27.4727 | 1 | 1 |
| caspase-1 isoform alpha precursor | Homo sapiens (human) | Potency | 26.9508 | 1 | 5 |
| caspase-3 | Homo sapiens (human) | Potency | 27.4727 | 1 | 1 |
| Caspase-7 | Homo sapiens (human) | Potency | 16.0599 | 1 | 4 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 20.9433 | 3 | 9 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 21.7773 | 2 | 9 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 25.4353 | 1 | 22 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 13.5864 | 3 | 9 |
| Chain A, Beta-lactamase | Escherichia coli K-12 | Potency | 67.7897 | 2 | 3 |
| Chain A, Breast cancer type 1 susceptibility protein | Homo sapiens (human) | Potency | 5.0119 | 1 | 3 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 29.1371 | 2 | 4 |
| Chain A, Ferritin light chain | Equus caballus (horse) | Potency | 20.5942 | 1 | 4 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 13.1417 | 2 | 18 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | Homo sapiens (human) | Potency | 41.4246 | 1 | 5 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 10.7501 | 3 | 17 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 20.3863 | 3 | 10 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 9.9398 | 1 | 16 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 13.1417 | 2 | 18 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 41.7485 | 2 | 7 |
| core-binding factor subunit beta isoform 2 | Homo sapiens (human) | Potency | 23.4221 | 3 | 3 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 9.0956 | 1 | 5 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 7.7037 | 1 | 6 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 16.3138 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 6.3962 | 1 | 4 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 14.3824 | 2 | 24 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 9.7717 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 25.9712 | 1 | 9 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 11.2452 | 2 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | Homo sapiens (human) | Potency | 28.9342 | 1 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | Potency | 27.2454 | 2 | 3 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 12.9707 | 1 | 6 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 48.5342 | 1 | 2 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 11.8160 | 1 | 2 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 41.7251 | 1 | 8 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 21.6964 | 1 | 12 |
| dopamine D1 receptor | Homo sapiens (human) | Potency | 29.0929 | 1 | 1 |
| endonuclease IV | Escherichia coli | Potency | 4.5858 | 2 | 2 |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | Potency | 22.3872 | 1 | 1 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 29.8295 | 12 | 54 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 22.5350 | 2 | 8 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 20.8722 | 9 | 21 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 11.4999 | 1 | 13 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 16.2949 | 4 | 7 |
| eyes absent homolog 2 isoform a | Homo sapiens (human) | Potency | 8.4936 | 1 | 1 |
| farnesoid X nuclear receptor | Homo sapiens (human) | Potency | 37.5569 | 4 | 8 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 45.6395 | 2 | 9 |
| fructose-bisphosphate aldolase A | Oryctolagus cuniculus (rabbit) | Potency | 22.3872 | 1 | 1 |
| G | Vesicular stomatitis virus | Potency | 16.3138 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 14.3824 | 1 | 12 |
| geminin | Homo sapiens (human) | Potency | 16.7733 | 4 | 19 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 28.2413 | 3 | 11 |
| glp-1 receptor, partial | Homo sapiens (human) | Potency | 16.3127 | 1 | 4 |
| GLS protein | Homo sapiens (human) | Potency | 13.6757 | 2 | 8 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 28.5621 | 1 | 9 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 30.0871 | 3 | 9 |
| glucokinase regulatory protein | Homo sapiens (human) | Potency | 12.0627 | 2 | 2 |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | Potency | 4.4668 | 1 | 1 |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | Potency | 33.0414 | 2 | 3 |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | Potency | 4.4668 | 1 | 1 |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | Potency | 4.4668 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | Homo sapiens (human) | Potency | 27.6962 | 1 | 4 |
| Guanine nucleotide-binding protein G | Homo sapiens (human) | Potency | 35.3940 | 2 | 5 |
| guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 13.1386 | 2 | 7 |
| heat shock protein beta-1 | Homo sapiens (human) | Potency | 27.0822 | 2 | 5 |
| hemoglobin subunit beta | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| hexokinase-4 isoform 1 | Homo sapiens (human) | Potency | 12.0627 | 2 | 2 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 6.6425 | 2 | 26 |
| histone acetyltransferase KAT2A isoform 1 | Homo sapiens (human) | Potency | 9.7455 | 1 | 7 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 8.8648 | 2 | 2 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 107.0600 | 1 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 29.1656 | 1 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 16.3138 | 1 | 2 |
| huntingtin isoform 2 | Homo sapiens (human) | Potency | 19.5147 | 1 | 2 |
| hypothetical protein, conserved | Trypanosoma brucei | Potency | 19.3602 | 4 | 8 |
| hypoxia-inducible factor 1 alpha subunit | Homo sapiens (human) | Potency | 53.1784 | 2 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 11.1363 | 2 | 10 |
| IDH1 | Homo sapiens (human) | Potency | 19.7347 | 1 | 2 |
| importin subunit beta-1 isoform 1 | Homo sapiens (human) | Potency | 28.5504 | 2 | 6 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 16.3138 | 1 | 4 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 16.3095 | 2 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 26.6381 | 1 | 4 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 26.6381 | 1 | 4 |
| Interferon beta | Homo sapiens (human) | Potency | 19.7979 | 2 | 8 |
| interleukin 8 | Homo sapiens (human) | Potency | 75.4754 | 1 | 2 |
| isocitrate dehydrogenase 1, partial | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 14.6417 | 1 | 6 |
| lethal factor (plasmid) | Bacillus anthracis str. A2012 | Potency | 15.8807 | 1 | 6 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 15.8033 | 4 | 16 |
| luciferase | Photuris pensylvanica (Pennsylania firefly) | Potency | 18.0789 | 3 | 5 |
| lysosomal alpha-glucosidase preproprotein | Homo sapiens (human) | Potency | 12.0231 | 6 | 10 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 13.8416 | 1 | 5 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 13.0030 | 2 | 25 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 26.2881 | 2 | 10 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0730 | 1 | 2 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 22.4067 | 1 | 7 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 7.6352 | 1 | 3 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 16.9244 | 2 | 6 |
| nonstructural protein 1 | Influenza A virus (A/WSN/1933(H1N1)) | Potency | 7.9075 | 1 | 4 |
| NPC intracellular cholesterol transporter 1 precursor | Homo sapiens (human) | Potency | 0.5349 | 1 | 3 |
| Nrf2 | Homo sapiens (human) | Potency | 23.7758 | 2 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 33.8816 | 4 | 12 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | Homo sapiens (human) | Potency | 14.5810 | 1 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | Homo sapiens (human) | Potency | 3.4895 | 1 | 1 |
| Nuclear receptor ROR-gamma | Homo sapiens (human) | Potency | 26.1626 | 1 | 2 |
| nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 16.5221 | 2 | 29 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 29.8247 | 3 | 15 |
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | Potency | 14.9763 | 1 | 2 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | Homo sapiens (human) | Potency | 69.1320 | 1 | 7 |
| Parkin | Homo sapiens (human) | Potency | 23.3047 | 3 | 4 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 11.8730 | 2 | 2 |
| peripheral myelin protein 22 | Rattus norvegicus (Norway rat) | Potency | 23.1083 | 1 | 3 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 20.6882 | 1 | 2 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 27.9838 | 5 | 15 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 31.5793 | 5 | 11 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 23.9341 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 21.0689 | 1 | 10 |
| PINK1 | Homo sapiens (human) | Potency | 33.5278 | 1 | 2 |
| plasminogen precursor | Mus musculus (house mouse) | Potency | 7.8833 | 1 | 3 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 8.1766 | 1 | 4 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 4.2547 | 1 | 4 |
| potassium voltage-gated channel subfamily H member 2 isoform d | Homo sapiens (human) | Potency | 11.5682 | 1 | 4 |
| PPM1D protein | Homo sapiens (human) | Potency | 20.9593 | 1 | 4 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 47.8016 | 2 | 8 |
| pregnane X receptor | Rattus norvegicus (Norway rat) | Potency | 57.5382 | 1 | 3 |
| progesterone receptor | Homo sapiens (human) | Potency | 37.0513 | 2 | 7 |
| pyruvate kinase | Leishmania mexicana mexicana | Potency | 15.8711 | 5 | 9 |
| pyruvate kinase PKM isoform a | Homo sapiens (human) | Potency | 12.8072 | 4 | 6 |
| pyruvate kinase PKM isoform b | Homo sapiens (human) | Potency | 14.9763 | 2 | 4 |
| Rap guanine nucleotide exchange factor 4 | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 31.4080 | 2 | 8 |
| ras-related protein Rab-9A | Homo sapiens (human) | Potency | 0.3611 | 1 | 3 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 19.5963 | 1 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 22.8386 | 3 | 14 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 26.9587 | 4 | 12 |
| RGS12 | Homo sapiens (human) | Potency | 12.5893 | 1 | 1 |
| runt-related transcription factor 1 isoform AML1b | Homo sapiens (human) | Potency | 23.4221 | 3 | 3 |
| serine-protein kinase ATM isoform a | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | Homo sapiens (human) | Potency | 20.4054 | 2 | 2 |
| serine/threonine-protein kinase PLK1 | Homo sapiens (human) | Potency | 2.9935 | 1 | 1 |
| shiga toxin 1 B subunit | Escherichia coli O157:H7 | Potency | 7.9805 | 1 | 1 |
| shiga toxin 1 variant A subunit | Escherichia coli O157:H7 | Potency | 25.7220 | 3 | 3 |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | Potency | 5.7988 | 1 | 1 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 31.8781 | 2 | 6 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 31.8781 | 2 | 6 |
| Smad3 | Homo sapiens (human) | Potency | 23.9742 | 1 | 9 |
| snurportin-1 | Homo sapiens (human) | Potency | 28.5504 | 2 | 6 |
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | Potency | 5.7988 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | Potency | 21.8959 | 1 | 2 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 10.2336 | 1 | 6 |
| TAR DNA-binding protein 43 | Homo sapiens (human) | Potency | 21.8180 | 1 | 4 |
| TDP1 protein | Homo sapiens (human) | Potency | 16.7411 | 2 | 35 |
| thioredoxin glutathione reductase | Schistosoma mansoni | Potency | 42.2395 | 1 | 2 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 45.8871 | 2 | 10 |
| Thrombopoietin | Homo sapiens (human) | Potency | 5.4415 | 2 | 6 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 27.3374 | 2 | 15 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 58.2425 | 4 | 7 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 26.1890 | 5 | 10 |
| thyrotropin-releasing hormone receptor | Homo sapiens (human) | Potency | 27.7247 | 1 | 1 |
| transcriptional regulator ERG isoform 3 | Homo sapiens (human) | Potency | 15.8489 | 1 | 1 |
| transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| tumor susceptibility gene 101 protein | Homo sapiens (human) | Potency | 19.9526 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 18.4927 | 1 | 1 |
| urokinase plasminogen activator surface receptor precursor | Mus musculus (house mouse) | Potency | 7.8833 | 1 | 3 |
| urokinase-type plasminogen activator precursor | Mus musculus (house mouse) | Potency | 7.8833 | 1 | 3 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 44.4539 | 2 | 9 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 13.9228 | 2 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | Homo sapiens (human) | Potency | 35.5874 | 5 | 12 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 28.9519 | 1 | 8 |
| Voltage-dependent calcium channel gamma-2 subunit | Mus musculus (house mouse) | Potency | 47.3288 | 1 | 2 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | Homo sapiens (human) | IC50 | 5.9775 | 2 | 4 |
| 10 kDa chaperonin | Escherichia coli | IC50 | 4.9250 | 2 | 4 |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 9.6500 | 1 | 2 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 1.7300 | 1 | 1 |
| 2-5A-dependent ribonuclease | Homo sapiens (human) | IC50 | 1.4325 | 4 | 4 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 6.1500 | 1 | 2 |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | Ki | 3.9000 | 1 | 1 |
| 5'-nucleotidase | Homo sapiens (human) | IC50 | 10.5400 | 1 | 1 |
| 5'-nucleotidase | Mus musculus (house mouse) | IC50 | 100.0000 | 1 | 1 |
| 60 kDa chaperonin | Escherichia coli K-12 | IC50 | 250.0000 | 1 | 2 |
| 60 kDa chaperonin | Escherichia coli | IC50 | 4.9250 | 2 | 4 |
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | IC50 | 9.6500 | 1 | 2 |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | IC50 | 80.0675 | 4 | 4 |
| Acetylcholinesterase | Homo sapiens (human) | IC50 | 15.5933 | 3 | 3 |
| Acyl carrier protein, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 34.0000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | IC50 | 7.7900 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 64.2717 | 4 | 6 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, germ cell type preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, intestinal | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.3500 | 2 | 2 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.3500 | 2 | 2 |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 3.3500 | 2 | 2 |
| Alpha-amylase | Geobacillus stearothermophilus | IC50 | 1.6700 | 1 | 1 |
| Alpha-amylase 1A | Homo sapiens (human) | IC50 | 2.3500 | 1 | 1 |
| Alpha-amylase 1A | Homo sapiens (human) | Ki | 2.6000 | 1 | 1 |
| Alpha-galactosidase A | Homo sapiens (human) | Ki | 18.0000 | 1 | 1 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | IC50 | 278.0000 | 1 | 1 |
| Alpha-glucosidase MAL12 | Saccharomyces cerevisiae S288C | Ki | 18.0000 | 1 | 1 |
| Alpha-glucosidase MAL32 | Saccharomyces cerevisiae S288C | IC50 | 175.0000 | 1 | 2 |
| Alpha-glucosidase MAL62 | Saccharomyces cerevisiae (brewer's yeast) | IC50 | 212,855.0000 | 2 | 2 |
| Alpha-mannosidase | Canavalia ensiformis (jack bean) | Ki | 270.0000 | 1 | 1 |
| Alpha-mannosidase 2 | Rattus norvegicus (Norway rat) | Ki | 50.0000 | 1 | 1 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 81.0100 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 7.6500 | 6 | 6 |
| Amine oxidase [flavin-containing] A | Mus musculus (house mouse) | IC50 | 0.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | Ki | 0.7100 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 5.8640 | 5 | 5 |
| Amine oxidase [flavin-containing] B | Mus musculus (house mouse) | IC50 | 0.3000 | 2 | 2 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | Ki | 21.5000 | 1 | 1 |
| Aminopeptidase N | Homo sapiens (human) | IC50 | 15.5000 | 1 | 1 |
| Aminopeptidase N | Sus scrofa (pig) | IC50 | 15.5000 | 1 | 1 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 11.0522 | 33 | 33 |
| Androgen receptor | Homo sapiens (human) | IC50 | 251.5945 | 1 | 2 |
| Angiotensin-converting enzyme | Homo sapiens (human) | Ki | 167.0000 | 1 | 1 |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Anthrax toxin receptor 2 | Homo sapiens (human) | IC50 | 0.4535 | 2 | 2 |
| Arachidonate 5-lipoxygenase | Sus scrofa (pig) | IC50 | 2,500.0000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 0.6670 | 3 | 3 |
| Aromatase | Homo sapiens (human) | Ki | 2.6000 | 1 | 1 |
| Arrestin, beta 1 | Homo sapiens (human) | IC50 | 1.5240 | 1 | 1 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 4.7100 | 1 | 1 |
| Beta lactamase (plasmid) | Pseudomonas aeruginosa | IC50 | 7.7510 | 1 | 1 |
| Beta-glucosidase | Agrobacterium tumefaciens | Ki | 12.0000 | 2 | 2 |
| Beta-glucosidase | Prunus avium (sweet cherry) | IC50 | 81.0000 | 1 | 1 |
| Beta-glucosidase A | Caldicellulosiruptor saccharolyticus | IC50 | 218.3333 | 3 | 3 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 8.0000 | 1 | 1 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 201.0617 | 5 | 6 |
| Beta-secretase 1 | Homo sapiens (human) | Ki | 3.3150 | 2 | 2 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 4.9580 | 5 | 5 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 350.5000 | 2 | 3 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 38.2699 | 8 | 10 |
| Calmodulin-1 | Homo sapiens (human) | IC50 | 33.4300 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 9.4456 | 5 | 9 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 6.6429 | 4 | 5 |
| Carbonic anhydrase 13 | Homo sapiens (human) | Ki | 9.7650 | 1 | 2 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 29.6878 | 5 | 9 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 13.5500 | 1 | 4 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 10.9476 | 2 | 5 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 2.7871 | 2 | 3 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 1.5850 | 3 | 4 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | IC50 | 2.2250 | 1 | 2 |
| Carbonyl reductase [NADPH] 1 | Homo sapiens (human) | Ki | 0.3550 | 1 | 2 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 9.6667 | 2 | 3 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 9.5000 | 1 | 2 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 9.6667 | 2 | 3 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 9.6667 | 2 | 3 |
| Caspase-1 | Homo sapiens (human) | IC50 | 4.0400 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 110.8000 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | IC50 | 2.3600 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | Homo sapiens (human) | Ki | 0.1010 | 1 | 1 |
| Ceramide glucosyltransferase | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Chain A, ARGINASE 1 | Rattus norvegicus (Norway rat) | Ki | 1,000.0000 | 1 | 3 |
| Chain A, Glycogen phosphorylase, muscle form | Oryctolagus cuniculus (rabbit) | Ki | 19.0100 | 1 | 2 |
| Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE | Homo sapiens (human) | Ki | 253.0000 | 1 | 1 |
| Cholinesterase | Equus caballus (horse) | IC50 | 106.9827 | 3 | 3 |
| Cholinesterase | Homo sapiens (human) | IC50 | 102.5000 | 2 | 2 |
| Class A sortase SrtA | Staphylococcus aureus | IC50 | 31.2600 | 3 | 3 |
| Coagulation factor X | Homo sapiens (human) | IC50 | 0.1700 | 1 | 1 |
| Coagulation factor X | Homo sapiens (human) | Ki | 0.5700 | 1 | 1 |
| Complex I intermediate-associated protein 30, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| CREB-binding protein | Homo sapiens (human) | IC50 | 25.0000 | 4 | 4 |
| Cyclin homolog | Herpesvirus saimiri (strain 11) | IC50 | 5.8500 | 1 | 4 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 7.1000 | 1 | 1 |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | IC50 | 5.8500 | 1 | 4 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 6.1300 | 3 | 6 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | IC50 | 5.8800 | 2 | 5 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 6.1300 | 3 | 6 |
| Cystathionine beta-synthase | Homo sapiens (human) | IC50 | 17.1000 | 1 | 1 |
| Cystathionine gamma-lyase | Homo sapiens (human) | IC50 | 400.0000 | 1 | 1 |
| Cysteine protease | Trypanosoma brucei rhodesiense | IC50 | 7.7500 | 1 | 1 |
| Cytochrome c oxidase subunit NDUFA4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 0.5077 | 3 | 3 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.0510 | 2 | 2 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 0.1995 | 4 | 4 |
| Cytochrome P450 1A2 | Homo sapiens (human) | Ki | 0.2800 | 2 | 2 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 5.2013 | 3 | 3 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.0160 | 2 | 2 |
| Cytochrome P450 2A6 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Cytochrome P450 2A6 | Homo sapiens (human) | Ki | 12.0000 | 1 | 1 |
| Cytochrome P450 2B6 | Homo sapiens (human) | IC50 | 25.0000 | 1 | 1 |
| Cytochrome P450 2C19 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Cytochrome P450 2C9 | Homo sapiens (human) | IC50 | 7.6125 | 2 | 2 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 20.4000 | 3 | 3 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 30.0000 | 2 | 2 |
| Cytosolic beta-glucosidase | Homo sapiens (human) | IC50 | 160.0000 | 2 | 2 |
| D-amino-acid oxidase | Sus scrofa (pig) | IC50 | 1.0700 | 2 | 2 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 104.2000 | 2 | 3 |
| Dipeptidyl peptidase 3 | Homo sapiens (human) | IC50 | 104.0500 | 1 | 2 |
| DNA gyrase subunit A | Escherichia coli K-12 | IC50 | 0.1441 | 10 | 10 |
| DNA gyrase subunit A | Mycobacterium tuberculosis H37Rv | IC50 | 3.9538 | 12 | 12 |
| DNA gyrase subunit A | Staphylococcus aureus | IC50 | 0.0383 | 13 | 13 |
| DNA gyrase subunit A | Escherichia coli K-12 | Ki | 0.0447 | 1 | 3 |
| DNA gyrase subunit A | Staphylococcus aureus | Ki | 0.0360 | 2 | 4 |
| DNA gyrase subunit B | Escherichia coli K-12 | IC50 | 0.1537 | 15 | 15 |
| DNA gyrase subunit B | Mycobacterium tuberculosis H37Rv | IC50 | 4.2224 | 11 | 11 |
| DNA gyrase subunit B | Mycolicibacterium smegmatis | IC50 | 25.8523 | 7 | 7 |
| DNA gyrase subunit B | Mycolicibacterium smegmatis MC2 155 | IC50 | 0.0460 | 1 | 1 |
| DNA gyrase subunit B | Staphylococcus aureus | IC50 | 0.0474 | 19 | 19 |
| DNA gyrase subunit B | Streptococcus pneumoniae TIGR4 | IC50 | 0.0370 | 1 | 1 |
| DNA gyrase subunit B | Escherichia coli K-12 | Ki | 0.0353 | 2 | 4 |
| DNA gyrase subunit B | Staphylococcus aureus | Ki | 0.0360 | 2 | 4 |
| DNA topoisomerase | Streptococcus pneumoniae | IC50 | 2.0300 | 1 | 1 |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | IC50 | 256.0000 | 1 | 1 |
| DNA topoisomerase 4 subunit A | Staphylococcus aureus | IC50 | 25.6000 | 5 | 5 |
| DNA topoisomerase 4 subunit A | Escherichia coli K-12 | Ki | 0.0447 | 1 | 3 |
| DNA topoisomerase 4 subunit B | Staphylococcus aureus | IC50 | 22.6500 | 6 | 6 |
| DNA topoisomerase 4 subunit B | Escherichia coli K-12 | Ki | 0.0447 | 1 | 3 |
| DNA-3-methyladenine glycosylase | Homo sapiens (human) | IC50 | 2.6000 | 1 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | Mus musculus (house mouse) | IC50 | 1.5600 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 5.0000 | 1 | 1 |
| estrogen receptor beta isoform 1 | Homo sapiens (human) | IC50 | 2.9272 | 1 | 2 |
| eukaryotic translation initiation factor 4 gamma 1 isoform 4 | Homo sapiens (human) | IC50 | 1.1500 | 1 | 1 |
| eukaryotic translation initiation factor 4E isoform 1 | Mus musculus (house mouse) | IC50 | 1.1500 | 1 | 1 |
| Fatty acid synthase | Gallus gallus (chicken) | IC50 | 6.1500 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 1.6000 | 1 | 1 |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | IC50 | 5.8500 | 1 | 4 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 7.1000 | 1 | 1 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | IC50 | 7.1000 | 1 | 1 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | IC50 | 7.1000 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | IC50 | 2.5000 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Ki | 0.9200 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | Homo sapiens (human) | Ki | 3.0200 | 1 | 1 |
| Gamma-butyrobetaine dioxygenase | Homo sapiens (human) | IC50 | 0.7420 | 5 | 5 |
| Genome polyprotein | Coxsackievirus B3 (strain Nancy) | IC50 | 1.1000 | 1 | 1 |
| Genome polyprotein | Hepatitis C virus (isolate BK) | IC50 | 36.0000 | 1 | 1 |
| Genome polyprotein | | IC50 | 0.4005 | 4 | 4 |
| Genome polyprotein | Human rhinovirus sp. | IC50 | 150.0000 | 1 | 1 |
| Genome polyprotein | Zika virus | IC50 | 14.2000 | 1 | 1 |
| Genome polyprotein | | Ki | 0.0032 | 21 | 21 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | IC50 | 39.8550 | 1 | 2 |
| Glucose-6-phosphate 1-dehydrogenase | Homo sapiens (human) | Ki | 4.8655 | 4 | 4 |
| glucose-6-phosphate 1-dehydrogenase isoform b | Homo sapiens (human) | IC50 | 13.2000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | IC50 | 15.0867 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | IC50 | 1.4852 | 5 | 5 |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | IC50 | 0.3253 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | IC50 | 0.3253 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | IC50 | 0.3253 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | IC50 | 0.3253 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | IC50 | 0.3253 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | IC50 | 0.3253 | 3 | 3 |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | Ki | 0.1700 | 1 | 1 |
| Glutathione S-transferase P | Homo sapiens (human) | IC50 | 69.0000 | 1 | 1 |
| Glycogen debranching enzyme | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Glycogen debranching enzyme | Oryctolagus cuniculus (rabbit) | IC50 | 0.1900 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 7.2000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 8.4077 | 3 | 3 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 4.6932 | 2 | 5 |
| Heat shock protein HSP 90 | Oryctolagus cuniculus (rabbit) | IC50 | 382.0000 | 2 | 2 |
| Heat shock protein HSP 90-beta | Homo sapiens (human) | IC50 | 231.0000 | 1 | 1 |
| Hematopoietic prostaglandin D synthase | Homo sapiens (human) | IC50 | 11.6000 | 2 | 2 |
| Heme oxygenase 1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Heme oxygenase 2 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 0.9009 | 1 | 1 |
| Histone acetyltransferase p300 | Homo sapiens (human) | IC50 | 21.9167 | 6 | 6 |
| Histone deacetylase 1 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 1 | Homo sapiens (human) | Ki | 50.7900 | 1 | 1 |
| Histone deacetylase 11 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 2 | Homo sapiens (human) | Ki | 97.6700 | 1 | 1 |
| Histone deacetylase 3 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 4 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 5 | Homo sapiens (human) | IC50 | 95.2000 | 2 | 2 |
| Histone deacetylase 6 | Homo sapiens (human) | IC50 | 51.6500 | 4 | 4 |
| Histone deacetylase 7 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Histone deacetylase 8 | Homo sapiens (human) | Ki | 64.9800 | 1 | 1 |
| Histone deacetylase 9 | Homo sapiens (human) | IC50 | 95.3500 | 2 | 2 |
| Histone-lysine N-methyltransferase EHMT1 | Homo sapiens (human) | IC50 | 0.7300 | 1 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | Homo sapiens (human) | IC50 | 0.4000 | 1 | 1 |
| Histone-lysine N-methyltransferase SETD7 | Homo sapiens (human) | IC50 | 6.0200 | 1 | 1 |
| hypothetical protein SA1422 | Staphylococcus aureus subsp. aureus N315 | IC50 | 42.9000 | 2 | 2 |
| Indoleamine 2,3-dioxygenase 1 | Homo sapiens (human) | Ki | 0.0940 | 3 | 3 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | IC50 | 32.1000 | 1 | 1 |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | Ki | 5.5100 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit alpha | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Inhibitor of nuclear factor kappa-B kinase subunit beta | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Insulin-degrading enzyme | Homo sapiens (human) | IC50 | 33.3520 | 3 | 3 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 29.9200 | 5 | 5 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 4.8500 | 1 | 1 |
| intestinal alkaline phosphatase precursor | Mus musculus (house mouse) | IC50 | 18.7000 | 1 | 1 |
| Islet amyloid polypeptide | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Lactase-phlorizin hydrolase | Homo sapiens (human) | IC50 | 62.0000 | 1 | 1 |
| Lactase-phlorizin hydrolase | Rattus norvegicus (Norway rat) | IC50 | 36.3333 | 3 | 3 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 37.7936 | 2 | 3 |
| Large neutral amino acids transporter small subunit 1 | Homo sapiens (human) | IC50 | 200.0000 | 1 | 1 |
| large T antigen | Betapolyomavirus macacae | IC50 | 12.5450 | 1 | 2 |
| Low molecular weight phosphotyrosine protein phosphatase | Bos taurus (cattle) | IC50 | 10.0000 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 3.2733 | 3 | 3 |
| Lysosomal acid glucosylceramidase | Bos taurus (cattle) | IC50 | 210.0000 | 1 | 1 |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | IC50 | 280.3333 | 6 | 6 |
| Lysosomal acid glucosylceramidase | Homo sapiens (human) | Ki | 68.3333 | 3 | 3 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 39.2600 | 6 | 6 |
| Lysosomal alpha-glucosidase | Rattus norvegicus (Norway rat) | IC50 | 80.2500 | 5 | 5 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | Ki | 12.5295 | 2 | 2 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | IC50 | 2.4000 | 1 | 1 |
| Macrophage migration inhibitory factor | Homo sapiens (human) | Ki | 0.5700 | 2 | 2 |
| Maltase-glucoamylase, intestinal | Homo sapiens (human) | IC50 | 34.7614 | 7 | 7 |
| Mcl-1 | Homo sapiens (human) | IC50 | 2.9883 | 1 | 1 |
| Melatonin receptor type 1A | Homo sapiens (human) | Ki | 1.9000 | 1 | 1 |
| Methionine aminopeptidase 2 | Homo sapiens (human) | IC50 | 2.4300 | 1 | 1 |
| microphthalmia-associated transcription factor isoform 9 | Homo sapiens (human) | IC50 | 6.3810 | 3 | 3 |
| Microtubule-associated protein tau | Homo sapiens (human) | IC50 | 54.8750 | 4 | 4 |
| Microtubule-associated proteins 1A/1B light chain 3A | Homo sapiens (human) | IC50 | 42.9000 | 1 | 1 |
| Microtubule-associated proteins 1A/1B light chain 3A | Homo sapiens (human) | Ki | 8.8000 | 1 | 1 |
| Microtubule-associated proteins 1A/1B light chain 3B | Homo sapiens (human) | IC50 | 172.0000 | 1 | 1 |
| Microtubule-associated proteins 1A/1B light chain 3B | Homo sapiens (human) | Ki | 19.3000 | 1 | 1 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 22.4750 | 1 | 4 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 22.4750 | 1 | 4 |
| MPI protein | Homo sapiens (human) | IC50 | 0.2905 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Homo sapiens (human) | IC50 | 24.2000 | 1 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | Mus musculus (house mouse) | IC50 | 25.0000 | 1 | 1 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] 1 subunit C2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 1 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 2 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 3 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 4 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 4L | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 5 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| NADH-ubiquinone oxidoreductase chain 6 | Homo sapiens (human) | IC50 | 14.5000 | 2 | 2 |
| Neuraminidase | Influenza A virus (A/USSR/90/1977(H1N1)) | IC50 | 74.0000 | 2 | 2 |
| Neuraminidase | Influenza A virus (A/RI/5+/1957(H2N2)) | IC50 | 11.9000 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 43.9867 | 3 | 3 |
| Neuronal proto-oncogene tyrosine-protein kinase Src | Mus musculus (house mouse) | IC50 | 2.2000 | 1 | 1 |
| Neutral alpha-glucosidase AB | Homo sapiens (human) | IC50 | 472.8250 | 3 | 4 |
| Neutral alpha-glucosidase AB | Homo sapiens (human) | Ki | 410.0000 | 1 | 1 |
| neutrophil cytosol factor 1 | Homo sapiens (human) | IC50 | 0.3900 | 1 | 1 |
| Neutrophil cytosol factor 1 | Homo sapiens (human) | Ki | 125.0000 | 3 | 3 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 6.2000 | 1 | 1 |
| Non-lysosomal glucosylceramidase | Homo sapiens (human) | IC50 | 24.9500 | 4 | 4 |
| Non-structural protein 4A | | IC50 | 0.0007 | 3 | 3 |
| Non-structural protein 4A | | Ki | 0.0101 | 3 | 3 |
| NS3 protease | Hepatitis C virus subtype 1b | IC50 | 0.0044 | 4 | 4 |
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | IC50 | 67.6350 | 1 | 1 |
| Oligo-1,6-glucosidase IMA1 | Saccharomyces cerevisiae S288C | IC50 | 330.0000 | 1 | 1 |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | IC50 | 137.5000 | 3 | 4 |
| Oxysterols receptor LXR-beta | Homo sapiens (human) | IC50 | 150.0000 | 2 | 3 |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | IC50 | 25.5000 | 1 | 1 |
| P2Y purinoceptor 12 | Homo sapiens (human) | Ki | 23.2000 | 2 | 2 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 100.0000 | 1 | 1 |
| perilipin-1 | Homo sapiens (human) | IC50 | 6.2885 | 1 | 2 |
| perilipin-5 | Homo sapiens (human) | IC50 | 5.6665 | 1 | 2 |
| phosphoethanolamine/phosphocholine phosphatase isoform 1 | Homo sapiens (human) | IC50 | 0.1110 | 1 | 1 |
| Phospholipase A2 | Homo sapiens (human) | IC50 | 11.1000 | 1 | 1 |
| phosphomannomutase 2 | Homo sapiens (human) | IC50 | 0.6720 | 1 | 1 |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | IC50 | 187.0000 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 20.0000 | 1 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 16.2500 | 2 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 23.9000 | 1 | 1 |
| Potassium voltage-gated channel subfamily A member 3 | Homo sapiens (human) | IC50 | 101.0000 | 1 | 1 |
| Probable maltase-glucoamylase 2 | Homo sapiens (human) | IC50 | 115.7500 | 2 | 2 |
| Procathepsin L | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Prostaglandin E synthase | Homo sapiens (human) | IC50 | 1.8000 | 3 | 3 |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | IC50 | 280.0000 | 1 | 2 |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | IC50 | 55.6567 | 2 | 3 |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | IC50 | 2.1000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 51.0567 | 2 | 3 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 7.7500 | 4 | 4 |
| Protein E6 | Human papillomavirus 16 | IC50 | 4.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | IC50 | 1.0000 | 1 | 1 |
| Protein-lysine 6-oxidase | Homo sapiens (human) | Ki | 79.0000 | 1 | 1 |
| Prothrombin | Bos taurus (cattle) | IC50 | 0.0800 | 2 | 2 |
| Prothrombin | Bos taurus (cattle) | Ki | 3.9000 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | Homo sapiens (human) | Ki | 5,100.0000 | 1 | 1 |
| Putative alpha-glucosidase | Oryza sativa Japonica Group (Japanese rice) | IC50 | 0.0400 | 2 | 2 |
| Pyruvate kinase PKM | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Receptor-type tyrosine-protein phosphatase S | Homo sapiens (human) | IC50 | 4.3000 | 1 | 1 |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | IC50 | 21.6850 | 2 | 2 |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | IC50 | 20.3900 | 3 | 3 |
| Replicase polyprotein 1ab | Human coronavirus 229E | IC50 | 21.6850 | 2 | 2 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 8.4928 | 14 | 18 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 25.7130 | 6 | 10 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 2.4000 | 1 | 1 |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | IC50 | 100.0000 | 1 | 1 |
| Ribonuclease HI | Escherichia coli K-12 | IC50 | 20.0000 | 1 | 1 |
| RNA polymerase beta subunit (EC 2.7.7.6), partial | Escherichia coli | IC50 | 11.6872 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 3.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Homo sapiens (human) | Ki | 53.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | Rattus norvegicus (Norway rat) | Ki | 5.8000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Homo sapiens (human) | Ki | 8.6000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | Ki | 19.4000 | 1 | 1 |
| Serine racemase | Homo sapiens (human) | Ki | 366.0000 | 1 | 1 |
| Serine/threonine-protein kinase PAK 1 | Homo sapiens (human) | IC50 | 16.0000 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 8.8500 | 1 | 2 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 12.6000 | 1 | 1 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 890.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Mus musculus (house mouse) | IC50 | 2,238.7200 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Mus musculus (house mouse) | IC50 | 1,348.9600 | 1 | 1 |
| Sodium- and chloride-dependent glycine transporter 1 | Homo sapiens (human) | IC50 | 68.8000 | 2 | 2 |
| Sodium- and chloride-dependent glycine transporter 2 | Homo sapiens (human) | IC50 | 128.0000 | 1 | 1 |
| Solute carrier family 15 member 2 | Homo sapiens (human) | Ki | 3,095.1500 | 1 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 4 | Mus musculus (house mouse) | Ki | 60.0000 | 1 | 1 |
| Solute carrier family 22 member 12 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Solute carrier family 22 member 12 | Rattus norvegicus (Norway rat) | IC50 | 18.0000 | 1 | 1 |
| Solute carrier family 22 member 12 | Homo sapiens (human) | Ki | 5.7400 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | IC50 | 9.7000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | IC50 | 2.7000 | 1 | 1 |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | Ki | 3.8250 | 4 | 4 |
| Solute carrier organic anion transporter family member 2B1 | Homo sapiens (human) | IC50 | 4.5000 | 1 | 1 |
| Sortase A | Streptococcus mutans | IC50 | 18.7000 | 1 | 2 |
| Spike glycoprotein | Betacoronavirus England 1 | IC50 | 0.6700 | 1 | 1 |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | IC50 | 0.6700 | 1 | 1 |
| Squalene monooxygenase | Rattus norvegicus (Norway rat) | IC50 | 0.3000 | 2 | 2 |
| steroidogenic factor 1 | Homo sapiens (human) | IC50 | 67.6350 | 1 | 1 |
| Structural capsid protein | Human immunodeficiency virus 1 | IC50 | 0.0467 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 45.7000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 45.7000 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 77.8333 | 3 | 3 |
| Sucrase-isomaltase, intestinal | Rattus norvegicus (Norway rat) | IC50 | 26.9913 | 15 | 15 |
| Sulfhydryl oxidase 1 | Homo sapiens (human) | IC50 | 5.4000 | 1 | 1 |
| Telomere resolvase ResT | Borreliella burgdorferi B31 | IC50 | 8.6700 | 1 | 1 |
| Thioredoxin reductase 1, cytoplasmic | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 1, cytoplasmic | Rattus norvegicus (Norway rat) | IC50 | 185.0000 | 1 | 1 |
| Thioredoxin reductase 2, mitochondrial | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thioredoxin reductase 2, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 132.0000 | 1 | 1 |
| Thioredoxin reductase 3 | Homo sapiens (human) | IC50 | 40.4667 | 3 | 3 |
| Thiosulfate sulfurtransferase | Homo sapiens (human) | IC50 | 56.5000 | 1 | 2 |
| Tissue alpha-L-fucosidase | Bos taurus (cattle) | IC50 | 32.0000 | 1 | 1 |
| Tissue factor | Homo sapiens (human) | IC50 | 0.0132 | 1 | 1 |
| toll-like receptor 9 | Homo sapiens (human) | IC50 | 8.3620 | 1 | 1 |
| Toxin B | Clostridioides difficile | IC50 | 0.0172 | 1 | 1 |
| TPA: protein transporter TIM10 | Saccharomyces cerevisiae S288C | IC50 | 10.0933 | 2 | 3 |
| TPA: protein transporter TIM23 | Saccharomyces cerevisiae S288C | IC50 | 0.8800 | 1 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | IC50 | 125.9465 | 1 | 2 |
| Transient receptor potential cation channel subfamily V member 2 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| Transmembrane protease serine 2 | Homo sapiens (human) | IC50 | 0.6700 | 1 | 1 |
| Transthyretin | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Trehalase | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Trehalase | Rattus norvegicus (Norway rat) | IC50 | 41.6667 | 3 | 3 |
| Trehalase | Sus scrofa (pig) | IC50 | 41.0000 | 2 | 2 |
| Trehalose synthase/amylase TreS | Mycobacterium tuberculosis CDC1551 | Ki | 0.2500 | 1 | 1 |
| Triosephosphate isomerase | Oryctolagus cuniculus (rabbit) | Ki | 2.6000 | 1 | 1 |
| Tyrosinase | Homo sapiens (human) | IC50 | 5.0000 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 28.0000 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Ki | 7.9000 | 1 | 1 |
| UDP-glucose 4-epimerase | Homo sapiens (human) | IC50 | 0.0140 | 1 | 1 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 84.7780 | 5 | 5 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 84.7780 | 5 | 5 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 0.2260 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | Rattus norvegicus (Norway rat) | IC50 | 100.0000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 2.2300 | 2 | 2 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 5.4700 | 1 | 2 |